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Objective: Prostate cancer is one of the most common malignant neoplasms in elderly males, with radical prostatectomy being the established therapeutic approach for localized disease. Patients undergoing this surgical procedure frequently experience increased negative emotions and symptomatology during the perioperative period, likely due to concerns about the illness and its treatment. The present study aims to investigate the effects of a novel educational approach involving a whole-process visualization and collaborative nursing discussions on perioperative symptoms and emotional well-being in radical prostatectomy patients. Methods: Data were prospectively collected from 310 patients admitted to the hospital between June 2021 and December 2023, all of whom were scheduled to undergo radical prostatectomy. These patients were randomly assigned to either the intervention group (receiving new model education) or the control group (receiving conventional education), with 155 patients in each group. The study compared basic demographic information, anxiety and depression scores, fear of disease progression scores, quality-of-life scores, main symptom scores, and changes in perioperative vital signs between the two groups. Results: No statistically significant differences were observed between the two groups in terms of age, comorbidities, insurance type, education level, income, and tumor history (P > 0.05). Similarly, there were no significant differences in anxiety and depression scores, proportion of patients with anxiety and depression, vital signs, and fear of disease progression scores between the two groups at Time 1 stage (P > 0.05). During stages Time 2 and Time 3, the intervention group exhibited lower anxiety and depression scores, a lower proportion of anxious and depressed patients, as well as significantly reduced blood pressure and heart rate fluctuations compared to the control group (P < 0.05). Following radical prostatectomy, the main symptoms of patients, such as pain, nausea, and fatigue, were assessed using the MADIS Symptom Assessment Scale on days 1–3 post-surgery. The intervention group exhibited significantly lower scores for three symptoms compared to the control group (P < 0.05); at Time 4 stage, the patients in the intervention group also demonstrated significantly improved quality-of-life scores compared to the control group (P < 0.05). Additionally, blood pressure and heart rate of patients returned to baseline levels at Time 4 stage, with no significant difference between the two groups (P > 0.05). Nevertheless, the anxiety and depression scores in the intervention group at the Time 4 stage remained significantly lower than those in the control group (P < 0.05). Additionally, the fear of disease progression scores in both groups were lower than those at the Time 1 stage, with a more pronounced improvement observed in the intervention group compared to the control group (P < 0.05). Conclusion: Patients diagnosed with malignant tumors often experience fear and anxiety regarding the progression of their disease and upcoming surgery, as well as uncertainty surrounding their treatment and prognosis. This heightened emotional distress can contribute to a greater symptom burden during the perioperative period. Utilizing a whole-process visualization and collaborative nursing discussion approach, as compared to traditional communication methods, has been shown to alleviate patients' fears, reduce anxiety and depression, and ultimately lessen the symptom burden experienced during the perioperative phase. Ultimately, this approach can enhance the overall quality of life for patients facing malignant tumors. [ABSTRACT FROM AUTHOR]

Abstract Background One of the most prevalent unmet needs among cancer patients is the fear of disease progression (FoP). This cross-sectional study aimed to identify the relationships among uncertainty in illness (UI), intolerance of uncertainty (IU), and FoP among newly diagnosed cancer patients and to verify the mediating role of IU in the relationship between UI and FoP. Methods A total of 202 newly diagnosed cancer patients (male: 105, 51.98%; mean age: 47.45 ± 14.8 years; lung cancer: 49, 24.26%) were recruited by convenience sampling. The patients completed a homemade questionnaire that assessed demographic characteristics, the Fear of Progression Questionnaire-Short Form, the Mishel Uncertainty in Illness Scale, and the Intolerance of Uncertainty Scale. Results The prevalence of FoP among newly diagnosed cancer patients was 87.62%, and the prevalences of high, medium, and low levels of UI were 15.84%, 73.27%, and 10.89%, respectively. The mean score on the Intolerance of Uncertainty Scale was 41.19 ± 10.11. FoP among newly diagnosed cancer patients was positively correlated with UI (r = 0.656, P

Abstract Objective This study aims to assess the levels of social support, fear of disease progression (FOP) and health promotion behaviors in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS), and to examine the associations between FOP, social support, and health promotion behaviors in OSAHS patients, with a focus on exploring the mediating role of social support. The findings aim to provide insights for enhancing health promotion behaviors among OSAHS patients in China and to offer a theoretical foundation for healthcare professionals in devising intervention strategies to promote health behaviors in individuals with OSAHS. Methods This cross-sectional study included 307 patients diagnosed with OSAHS in Jinzhou City, Liaoning province. The survey instruments utilized included the Demographic Characteristics Questionnaire, Social Support Rating Scale (SSRS), Fear of Disease Progression Scale (Fop-Q-SF), and Health-Promoting Lifestyle Scale (HPLP II). Pearson correlation analysis was employed to assess correlations, while multiple linear regression and structural equation modeling were utilized to explore potential mediation effects. Results In the OSAHS patient population, FOP (r=-0.55, p

Abstract The study aims to explore the relationship among metacognition (MC), fear of disease of progression (FoP), psychological distress (PD), and quality of life (QoL), and verify whether FoP and PD have a chain mediating effect between MC and QoL. 231 hematologic tumor patients in a large tertiary hospital were investigated by using Meta-Cognitions Questionnaire-30, Fear of Progression Questionnaire-Short Form, Hospital Anxiety and Depression Scale, and Functional Assessment of Cancer Therapy scale. Data analyses were performed using IBM SPSS (version 25.0) and the PROCESS macro (version 4.1). The results showed that the direct impact of MC on QoL was not statistically significant. However, the indirect influence of MC on QoL manifest through the independent influences of PD and FoP, as well as the chain mediating effect of “PD → FoP.” In addition, all four dimensions of QoL (physical, social and family, emotional, and functional) satisfy the chain mediation model, except for the social and family domain. These insights advance our comprehension of the intricate interplay between MC and QoL, underscoring the importance of improving MC to alleviate patients' PD, mitigate FoP, and ultimately improve the QoL of hematologic tumor patients.

BackgroundType 2 diabetes mellitus is one of the most prevalent diseases， which imposes a heavy burden on patients' families and the society. Sleep disorders are recognized as risk factors for the development of diabetes， which may affect the onset and development of diabetes through neuro-endocrino-metabolic pathways， so identifying the factors responsible for the sleep quality of diabetic patients is of great importance in improving their sleep quality.ObjectiveTo investigate the relationship among fear of disease progression， executive function and sleep quality in patients with type 2 diabetes mellitus， so as to provide references for improvement of sleep quality in patients with type 2 diabetes mellitus.MethodsA sample of 197 patients with type 2 diabetes mellitus who were admitted to the Endocrinology Department of the Second Affiliated Hospital of the Air Force Military Medical University from January to May 2023 and met the criteria defined in the Guideline for the Prevention and Treatment of Type 2 Diabetes Mellitus in China （2020 edition） were consecutively selected. All subjects were assessed using Fear of Progression Questionnaire-Short Form （FoP-Q-SF）， Behavior Rating Inventory of Executive Function-Adult version （BRIEF-A） and Pittsburgh Sleep Quality Index （PSQI）. Then the Process macro for SPSS （Model 4） and Bootstrap technique were applied to examine the mediating effect of executive function on the relationship between fear of disease progression and sleep quality in patients with type 2 diabetes mellitus.Results①75 patients （38.07%） with type 2 diabetes mellitus were found to have sleep problems. ②PSQI score in patients with type 2 diabetes mellitus was positively correlated with FoP-Q-SF score and BRIEF-A score （r=0.159， 0.287， P

The study aims to explore the relationship among metacognition (MC), fear of disease of progression (FoP), psychological distress (PD), and quality of life (QoL), and verify whether FoP and PD have a chain mediating effect between MC and QoL. 231 hematologic tumor patients in a large tertiary hospital were investigated by using Meta-Cognitions Questionnaire-30, Fear of Progression Questionnaire-Short Form, Hospital Anxiety and Depression Scale, and Functional Assessment of Cancer Therapy scale. Data analyses were performed using IBM SPSS (version 25.0) and the PROCESS macro (version 4.1). The results showed that the direct impact of MC on QoL was not statistically significant. However, the indirect influence of MC on QoL manifest through the independent influences of PD and FoP, as well as the chain mediating effect of "PD → FoP." In addition, all four dimensions of QoL (physical, social and family, emotional, and functional) satisfy the chain mediation model, except for the social and family domain. These insights advance our comprehension of the intricate interplay between MC and QoL, underscoring the importance of improving MC to alleviate patients' PD, mitigate FoP, and ultimately improve the QoL of hematologic tumor patients. [ABSTRACT FROM AUTHOR]

We examined the mediating role of depression and anxiety on the relationship between fear of disease progression (FoP) and antiretroviral therapy (ART) adherence and the moderating role of social support in the FoP-depression/anxiety-ART adherence relationship in persons with HIV/AIDS (PWHA). 202 PWHA completed self-report measures. Simple mediation and moderated mediation analyses were performed. FoP was directly and negatively associated with ART adherence, and the mediating role of depression in this relationship was significant. Indirect effect of FoP mediated by anxiety on ART adherence was not significant. The moderating effect of social support was significant in the FoP-depression pathway, while the indirect effect of FoP on ART adherence mediated by depression was greatest at a higher level of social support and lower level of FoP. The results suggest the relevance of high FoP and depression-mediated FoP in ART adherence and social support may attenuate the negative impact of FoP. [ABSTRACT FROM AUTHOR]

Aims Design Methods Results Conclusions Implications for the Profession and Patient Care Impact Reporting Method Patient or Public Contribution To explore the effect of post‐stroke fatigue (PSF) on post‐stroke depression (PSD) and examine the mediating effects of fear of disease progression (FOP) and resilience between PSF and PSD.A cross‐sectional study.A total of 315 stroke patients participated in the questionnaire survey between November 2022 and June 2023. Data were collected using the General Information Questionnaire, Fatigue Severity Scale, Fear of Disease Progression Questionnaire‐Short Form, Connor–Davidson Resilience Scale‐10 Item and Hospital Anxiety and Depression Scale‐Depression Subscale. Data were analysed by descriptive analysis, Mann–Whitney U‐test, Kruskal–Wallis H‐test, Pearson or Spearman correlation, hierarchical regression analysis and mediation analysis.PSF had a significant positive total effect on PSD (β = .354, 95% CI: .251, .454). Additionally, FOP and resilience played a partial parallel‐mediating role in the relationship between PSF and PSD (β = .202, 95% CI: .140, .265), and the total indirect effect accounted for 57.06% of the total effect.FOP and resilience parallelly mediated the effect of PSF on PSD, which may provide a novel perspective for healthcare professionals in preventing PSD. Targeted interventions aiming at reducing PSF, lowering FOP levels and enhancing resilience may be possible ways to alleviate PSD.Interventions that tail to reducing PSF, lowering FOP levels and enhancing resilience may be considered as possible ways to alleviate PSD.This study enriched the literature by exploring the effect of PSF on PSD and further examining the mediating effects of FOP and resilience between PSF and PSD. Findings emphasized the important effects of PSF, FOP and resilience on PSD.The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for cross‐sectional studies was used to guide reporting.One tertiary hospital assisted participants recruitment. [ABSTRACT FROM AUTHOR]

Objective To investigate the influencing factors of fear of disease progression (FoP) in patients with cervical squamous intraepithelial lesions (SIL). Methods A total of 80 SIL patients admitted to the hospital from January 2021 to December 2022 were selected to evaluate the FoP levels of all patients, compare the Fear of Disease Progression Simplified Scale (Fop-Q-SF) scores of SIL patients with different characteristics, and focus on analyzing the influencing factors of the FoP levels of SIL patients. Results In 80 patients, the average Fop-Q-SF score was (34. 65±5. 11); the difference was statistically significant when comparing the Fop-Q-SF scores of patients with different levels of hope, literacy level, age, and social support (P＜0. 05); and low social support, old age, low literacy level, and low level of hope were the influencing factors for the FoP level of patients with SIL (P＜0. 05). Conclusion The level of FoP in SIL patients is higher, which may be related to social support, age, hope level and education level. [ABSTRACT FROM AUTHOR]

Objective: To explore the mediating effect of shame in patients with malignant haematological diseases between fear of disease progression and social alienation.Methods: Recruiting 310 patients with haematological malignancies as the research population, the convenience sampling method was used to investigate the general information questionnaire, the fear of disease progression scale, the social influence scale and the general alienation scale.Results: The patients with haematological malignancies scored (36.02 ± 9.74) points for fear of disease progression, (58.02 ± 9.52) points for stigma and (31.31 ± 5.85) points for social alienation. Social alienation in patients with haematologic malignancies was positively correlated with stigma (r = 0.500, P

Background Type 2 diabetes mellitus is one of the most prevalent diseases, which imposes a heavy burden on patients' families and the society. Sleep disorders are recognized as risk factors for the development of diabetes, which may affect the onset and development of diabetes through neuro-endocrino-metabolic pathways, so identifying the factors responsible for the sleep quality of diabetic patients is of great importance in improving their sleep quality. Objective To investigate the relationship among fear of disease progression, executive function and sleep quality in patients with type 2 diabetes mellitus, so as to provide references for improvement of sleep quality in patients with type 2 diabetes mellitus. Methods A sample of 197 patients with type 2 diabetes mellitus who were admitted to the Endocrinology Department of the Second Affiliated Hospital of the Air Force Military Medical University from January to May 2023 and met the criteria defined in the Guideline for the Prevention and Treatment of Type 2 Diabetes Mellitus in China (2020 edition) were consecutively selected. All subjects were assessed using Fear of Progression Questionnaire- Short Form (FoP-Q-SF), Behavior Rating Inventory of Executive Function-Adult version (BRIEF-A) and Pittsburgh Sleep Quality Index (PSQI) . Then the Process macro for SPSS (Model 4) and Bootstrap technique were applied to examine the mediating effect of executive function on the relationship between fear of disease progression and sleep quality in patients with type 2 diabetes mellitus. Results ①75 patients (38. 07%) with type 2 diabetes mellitus were found to have sleep problems. ②PSQI score in patients with type 2 diabetes mellitus was positively correlated with FoP-Q-SF score and BRIEF-A score (r=0. 159, 0. 287, P<0. 01). ③ Executive function mediated the relationship between fear of disease progression and sleep quality, the indirect value was 0. 076 (95% CI： 0. 022~0. 146), accounting for 39. 58% of the total effect. Conclusion Sleep disorders are common in patients with type 2 diabetes mellitus, and executive function may play a medicating role in the relationship between fear of disease progression and sleep quality. [ABSTRACT FROM AUTHOR]

Objective: To investigate the level of fear of progression (FoP) in patients with H-type hypertension combined with acute ischemic stroke (AIS), and to analyze the influencing factors of FoP in patients with H-type hypertension combine with AIS. Methods: 159 patients with H-type hypertension combine with AIS admitted to the The First Affiliated Hospital of the Chinese People's Liberation Army Air Force Medical University from July 2020 to March 2023 were selected. Patient's FoP were evaluated by chinese version of the fear of disease progression simplified scale (FoP-Q-SF), patients were divided into FoP group and non-FoP group according to whether FoP occurred. The factors affecting FoP in patients with H-type hypertension combine with AIS were analyzed by multivariate Logistic regression analysis. Results: 159 questionnaires were distributed, and 154 were recovered, with a recovery rate of 96.86%. 69 cases (44.81%) of patients had FoP. The age, proportion of women, family economic income<5000 yuan/month, proportion of hemiplegia, National Institutes of Health Stroke Scale (NHISS) score and proportion of poor social support in FoP group were higher than those in non-FoP group(P<0.05), and self-care ability in daily life (ADL) score and general self-efficacy scale (GSES) score were lower than those in non-FoP group(P<0.05). Multivariate logistic regression analysis showed that Older age, female and family economic income<5000 yuan/month were risk factors for FoP in patients with H-type hypertension combine with AIS(P<0.05), and high ADL score, high GSES score and high social support were protective factors(P<0.05). Conclusion: The incidence of FoP in patients with H-type hypertension combined with AIS is higher, age, gender, economic status, self-care ability, self-efficacy and social support are the influencing factors of FoP in patients with H-type hypertension combine with AIS. [ABSTRACT FROM AUTHOR]

Abstract Background To explore the correlation between the current status of discharge preparation, quality of discharge teaching, and fear of disease progression among patients with lung cancer undergoing chemotherapy to provide a basis for improving patients' level of preparation. Methods In this cross‐sectional study, convenience sampling was used to select 452 patients with lung cancer who received chemotherapy and were admitted to the Department of Medical Oncology of the Cancer Hospital, between February 2023 and April 2023. A general information questionnaire, discharge preparation scale, quality of discharge teaching scale, and fear of disease progression scale were used to conduct surveys 2 h before the patients were discharged. Results The score for discharge preparation among lung cancer patients with chemotherapy was 99.11 ± 14.79 and the item score was 8.26 ± 1.23. The score for quality of discharge teaching was 193.23 ± 37.69, and that for fear of disease progression was 25.47 ± 8.92. Multiple linear regression analysis showed that sex, marital status, treatment period, quality of discharge teaching, and fear of disease progression influenced discharge readiness among patients with lung cancer receiving chemotherapy. Pearson's correlation analysis showed that the total quality of the discharge guidance score was positively correlated with the discharge readiness score (r = 0.288, p

BackgroundQuality of life， as a major criterion for judging the clinical outcome of ovarian cancer patients， can be affected by adverse psychological symptoms of patients. Meanwhile， fear of disease progression， as a frequent psychological symptom among cancer survivors， is significantly influenced by metacognition， while there is a paucity of research into the specific correlation among the three in patients with ovarian cancer.ObjectiveTo explore the correlation among fear of disease progression， metacognition and quality of life in patients with ovarian cancer， and to test the role of fear of disease progression in the relationship between metacognition and quality of life， so as to provide references for improving the quality of life in patients with ovarian cancer.MethodsA total of 135 patients with ovarian cancer hospitalized in Cangzhou People's Hospital of Hebei Province from January 2019 to December 2022 were selected. All subjects were requested to complete the Functional Assessment of Cancer Therapy-Ovarian Cancer （FACT-O）， Fear of Progression Questionnaire-Short Form （FoP-Q-SF） and Metacognition Questionnaire （MCQ） to assess their quality of life， fear of disease progression and metacognitive level. Pearson correlation analysis was adopted to examine the correlation among the above scales. Process v3.5 macro program was utilized to determine the mediating effect of fear of disease progression on the relationship between metacognition and quality of life， and nonparametric Bootstrap with bias-correction was used to test the mediating effect.ResultsA total of 122 patients （90.37%） with ovarian cancer completed the effective questionnaire survey. Patients scored （90.52±17.13） on FACT-O， （68.52±16.31） on MCQ， and （37.72±8.91） on FoP-Q-SF. Pearson correlation analysis denoted that FoP-Q-SF score was negatively correlated with FACT-O score （r=-0.412， P

Background: Endometriosis is a widespread problem in women of reproductive age, causing cyclical and non-cyclical pain in the pelvis and elsewhere, and associated with fatigue, fertility problems, and other symptoms. As a chronic pain problem, psychological variables are important in adjustment and quality of life, but have not been systematically studied. Methods: A systematic search of multiple databases was conducted to obtain surveys and qualitative studies of women’s experience of pain from endometriosis. Surveys were combined narratively; qualitative studies were combined by thematic synthesis, and the latter rated for methodological quality. Results: Over 2000 records were screened on title and abstract, and provided 22 surveys and 33 qualitative studies from which accounts could be extracted of the psychological components of pain in endometriosis. Surveys mostly addressed quality of life in endometriosis, with poorer quality of life associated with higher levels of pain and of distress, but few referred to coherent psychological models. Qualitative studies focused rather on women’s experience of living with endometriosis, including trajectories of diagnosis and treatment, with a few addressing meaning and identity. Thematic synthesis provided 10 themes, under the groupings of internal experience of endometriosis (impact on body, emotions, and life); interface with the external world (through self-regulation and social regulation); effects on interpersonal and social life, and encounters with medical care. Conclusions: The psychological components of pain from endometriosis only partly corresponded with standard psychological models of pain, derived from musculoskeletal pain studies, with fewer fears about physical integrity and more about difficulties of managing pain and other symptoms in social settings, including work. Better understanding of the particular psychological threats of endometriosis, and integration of this understanding into medical care with opportunities for psychologically-based pain management, would substantially improve the experience and quality of life of women with painful endometriosis. [ABSTRACT FROM AUTHOR]

Background: To explore the correlation between the current status of discharge preparation, quality of discharge teaching, and fear of disease progression among patients with lung cancer undergoing chemotherapy to provide a basis for improving patients' level of preparation. Methods: In this cross‐sectional study, convenience sampling was used to select 452 patients with lung cancer who received chemotherapy and were admitted to the Department of Medical Oncology of the Cancer Hospital, between February 2023 and April 2023. A general information questionnaire, discharge preparation scale, quality of discharge teaching scale, and fear of disease progression scale were used to conduct surveys 2 h before the patients were discharged. Results: The score for discharge preparation among lung cancer patients with chemotherapy was 99.11 ± 14.79 and the item score was 8.26 ± 1.23. The score for quality of discharge teaching was 193.23 ± 37.69, and that for fear of disease progression was 25.47 ± 8.92. Multiple linear regression analysis showed that sex, marital status, treatment period, quality of discharge teaching, and fear of disease progression influenced discharge readiness among patients with lung cancer receiving chemotherapy. Pearson's correlation analysis showed that the total quality of the discharge guidance score was positively correlated with the discharge readiness score (r = 0.288, p < 0.001). In contrast, the total fear of disease progression score was negatively correlated with the discharge preparation score (r = −0.252, p < 0.001). Conclusion: Discharge readiness among patients with lung cancer receiving chemotherapy was relatively at the good level, and there was a significant correlation between readiness for discharge, discharge teaching and fear of disease progression in these patients. Therefore, it is necessary to provide effective discharge guidance and implement targeted intervention measures to further improve patient preparation, reduce the fear of disease progression, and promote patient ability of coping with the disease and overall satisfaction. [ABSTRACT FROM AUTHOR]

The aim of this study was to forecast the mental well-being of individuals with multiple sclerosis (MS) by considering the quality of their family relationships, early maladaptive schemas, and their fear of disease progression. The research employed a descriptive-correlational design. The research subjects encompassed MS patients in the Kermanshah and Alborz provinces (Iran) during the year 2020. The sampling technique used was convenience sampling, leading to the selection of a total of 83 patients who actively participated in the research by completing questionnaires. The research tools utilized included the Mental Health Questionnaire (SCL-25), a shortened version of the Young Schema Questionnaire (YSQ – SF), the Quality of Relationships Questionnaire (QRI), and the brief form of the Fear of Disease Progression Questionnaire (FOP-Q-SF). Data analysis was carried out using SPSS version 24. The findings of the data analysis revealed a significant and positive association between all aspects of early maladaptive schemas and the mental well-being of MS patients. Conversely, none of the elements of the quality of relationships displayed a substantial connection with the mental health of MS patients. Furthermore, there was a significant and positive correlation between the fear of disease progression and the mental well-being of MS patients. Regression analysis results demonstrated that the variables of early maladaptive schemas and fear of disease progression collectively accounted for 52% and 35% variance of the mental health of MS patients, respectively. Given the unique attributes of MS, it is vital to focus on the mental well-being of these individuals. Exploring and examining other psychological variables can contribute to a deeper comprehension of the mental health of this particular group.

Abstract Background Health literacy (HL), self-efficacy (SE), social support (SS) and fear of disease progression (FOP) are all important factors affecting health-related quality of life (HRQoL) in cancer patients. However, their synergistic effects and underlying mechanisms on HRQoL in cancer patients remain unclear. Therefore, the purpose of this study was to construct a structural equation model (SEM) to explore the underlying mechanism of factors affecting HRQoL. It is hoped that this study will provide a theoretical basis for future interventions. Methods A cross-sectional design and convenience sampling method were used to investigate cancer inpatients in two general hospitals in Chongqing and Chengdu. Data were collected using structured scales, including HL, SE, SS, FOP and HRQoL. Finally, the SEM was constructed, and P ≤ 0.05 was considered significant. Results There were 1749 participants included in this study. Correlation analysis showed that all variables were significantly correlated with one another except for symptoms, physical health (PD) and social family (SF) (p

Background Quality of life， as a major criterion for judging the clinical outcome of ovarian cancer patients， can be affected by adverse psychological symptoms of patients. Meanwhile， fear of disease progression， as a frequent psychological symptom among cancer survivors， is significantly influenced by metacognition， while there is a paucity of research into the specific correlation among the three in patients with ovarian cancer. Objective To explore the correlation among fear of disease progression， metacognition and quality of life in patients with ovarian cancer， and to test the role of fear of disease progression in the relationship between metacognition and quality of life， so as to provide references for improving the quality of life in patients with ovarian cancer. Methods A total of 135 patients with ovarian cancer hospitalized in Cangzhou People's Hospital of Hebei Province from January 2019 to December 2022 were selected. All subjects were requested to complete the Functional Assessment of Cancer Therapy-Ovarian Cancer （FACT-O）， Fear of Progression Questionnaire-Short Form （FoP-Q-SF） and Metacognition Questionnaire （MCQ） to assess their quality of life， fear of disease progression and metacognitive level. Pearson correlation analysis was adopted to examine the correlation among the above scales. Process v3.5 macro program was utilized to determine the mediating effect of fear of disease progression on the relationship between metacognition and quality of life， and nonparametric Bootstrap with bias-correction was used to test the mediating effect.Results A total of 122 patients （90.37%） with ovarian cancer completed the effective questionnaire survey. Patients scored （90.52±17.13） on FACT-O， （68.52±16.31） on MCQ， and （37.72±8.91） on FoP-Q-SF. Pearson correlation analysis denoted that FoP-Q-SF score was negatively correlated with FACT-O score （r=-0.412， P<0.05） and positively correlated with MCQ score （r=0.241， P<0.05）， and MCQ score was negatively correlated with FACT-O score （r=-0.453， P<0.05）. Analysis demonstrated that the total effect of metacognition on quality of life was -0.298 （95% CI： -0.402~-0.186）. The direct effect of metacognition on quality of life was -0.219 （95% CI： -0.504~-0.277）， accounting for 73.49% of the total effect， and the indirect effect of metacognition on quality of life via fear of disease progression was -0.079 （95% CI： -0.162~-0.037）， accounting for 26.51% of the total effect. Conclusion Quality of life is reduced in patients with ovarian cancer， and fear of disease progression plays a partial mediating role in the relationship between metacognition and quality of life. [ABSTRACT FROM AUTHOR]

A poor quality of life (QoL) in patients with pulmonary hypertension (PH) is often associated with emotional disturbances and the ability to cope. Little is known, however, about the intrinsic links among the QoL, fear of disease progression (FoP), and coping styles in patients with PH. The purpose of this study was to elucidate the relationships among QoL, FoP, and coping styles in patients with PH. We conducted a cross‐sectional survey of 247 patients from a tertiary hospital in Jinan, China and analyzed the relationships using network analysis. Participants completed the World Health Organization's Quality of Life Questionnaire, Fear of Disease Progression Questionnaire and Simple Coping Style Questionnaire during the survey period. The total QoL, positive coping, and negative coping scores were 46.55 ± 10.46, 31.75 ± 6.85, and 18.75 ± 4.66, respectively. The QoL psychological domain had the strongest centrality, deserving more attention than other domains. The coping styles were bridge nodes that connected the whole network, where negative coping and social family FoP, and positive coping and both social and psychological QoL had the strongest positive correlations. There were no significant sex‐based or age‐based differences in the networks. To improve QoL and psychological well‐being in people with PH, healthcare professionals must focus on issues beyond the patient's physical health. Specifically, they should focus on positive coping styles, while developing interventions to promote positive coping and reduce negative coping styles. [ABSTRACT FROM AUTHOR]

Background: Fear of disease progression (FoP) is among the most prevalent and major psychological burdens breast cancer patients encounter. Excessive FoP may result in serious adverse effects for patients. FoP in breast cancer patients has gained attention recently; however, its prevalence in China is unknown. Objectives: This meta-analysis and systematic review aimed to assess the overall FoP among Chinese breast cancer patients to make recommendations for treatment and care. Methods: Systematic search databases included PubMed, EMbase, The Cohrane Library, Web of Science, CINAHL, PsycINFO and 4 Chinese databases (Wan Fang Data, CBM, VIP and CNKI). The retrieval time ranged from the database's establishment to March 20, 2023. After two researchers independently evaluated the literature, retrieved information, and assessed the risk of bias for the included literature, Stata 15.1 software was used to conduct a meta-analysis. Results: A total of 37 moderate or high-quality studies involving 9,689 breast cancer patients were included. Meta-analysis showed that the pooled mean score of FoP for Chinese breast cancer patients was 33.84 [95% CI (31.91, 35.77)], prediction interval (21.57 ~ 46.11). The subgroup study found that FoP levels varied among breast cancer patients of different regions, ages, educational levels, marital statuses, residences, illness stages, and disease statuses. Conclusion: Breast cancer patients have higher FoP scores. Healthcare workers should be concerned. We expect that more relevant research will be undertaken and more effective interventions will be developed. Patients can manage their illness and improve their quality of life by reducing their fears. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier: PROSPERO CRD42023408914. [ABSTRACT FROM AUTHOR]

The aim of this study was to forecast the mental well -being of individuals with multiple sclerosis (MS) by considering the quality of their family relationships, early maladaptive schemas, and their fear of disease progression. The research employed a descriptive -correlational design. The research subjects encompassed MS patients in the Kermanshah and Alborz provinces (Iran) during the year 2020. The sampling technique used was convenience sampling, leading to the selection of a total of 83 patients who actively participated in the research by completing questionnaires. The research tools utilized included the Mental Health Questionnaire (SCL -25), a shortened version of the Young Schema Questionnaire (YSQ – SF), the Quality of Relationships Questionnaire (QRI), and the brief form of the Fear of Disease Progression Questionnaire (FOP - Q -SF). Data analysis was carried out using SPSS version 24. The findings of the data analysis revealed a significant and positive association between all aspects of early maladaptive schemas and the mental well -being of MS patients. Conversely, none of the elements of the quality of relationships displayed a substantial connection with the mental health of MS patients. Furthermore, there was a significant and positive correlation between the fear of disease progression and the mental well-being of MS patients. Regression analysis results demonstrated that the variables of early maladaptive schemas and fear of disease progression collectively accounted for 52% and 35% variance of the mental health of MS patients, respectively. Given the unique attributes of MS, it is vital to focus on the mental well -being of these individuals. Exploring and examining other psychological variables can contribute to a deeper comprehension of the mental health of this particular group. [ABSTRACT FROM AUTHOR]

Background: Health literacy (HL), self-efficacy (SE), social support (SS) and fear of disease progression (FOP) are all important factors affecting health-related quality of life (HRQoL) in cancer patients. However, their synergistic effects and underlying mechanisms on HRQoL in cancer patients remain unclear. Therefore, the purpose of this study was to construct a structural equation model (SEM) to explore the underlying mechanism of factors affecting HRQoL. It is hoped that this study will provide a theoretical basis for future interventions. Methods: A cross-sectional design and convenience sampling method were used to investigate cancer inpatients in two general hospitals in Chongqing and Chengdu. Data were collected using structured scales, including HL, SE, SS, FOP and HRQoL. Finally, the SEM was constructed, and P ≤ 0.05 was considered significant. Results: There were 1749 participants included in this study. Correlation analysis showed that all variables were significantly correlated with one another except for symptoms, physical health (PD) and social family (SF) (p < 0.01). The SEM of the HRQoL had a good overall fit (GFI = 0.943, AGFI = 0.917, NFI = 0.950, RFI = 0.936, CFI = 0.955, IFI = 0.955, RMSEA = 0.072). The model indicated that HL had the strongest correlation with HRQoL (β = 0.398, p < 0.01), followed by FOP (β = -0.364, p < 0.01), SE (β = 0.347, p < 0.01) and SS (β = 0.184, p < 0.01). Conclusions: The HRQoL of cancer patients is correlated with HL, SS, SE and FOP. HL can directly affect HRQoL and mediate HRQoL through SS and SE. Future programs should consider HL promotion, SE improvement and SS expansion as the breakthrough point when designing targeted intervention strategies. At the same time, the importance of the impact of FOP on the HRQoL of patients with cancer should not be ignored. [ABSTRACT FROM AUTHOR]

To evaluate the adaptability of female teachers with breast cancer who returned to work after surgery in Xinjiang and to analyze the influencing factors so as to provide a scientific basis for female teachers with cancer to better return to work. Methods A convenience sampling method was used to investigate the female teachers who had returned to work after breast cancer surgery from 2019 to 2021, with the questionnaires including the general information questionnaire, the adaptation scale for returning to work for cancer patients, the simplified scale for fear of disease progression for cancer patients, and the social support scale. Multiple linear regression was used to explore the influencing factors of patients' adaptability to return to work. Results Totally 200 female teachers with breast cancer after surgery were investigated. The scores of adaptability to return-to-work and fear of disease progression were (60.19 ± 10.98) and (32.18 ± 6.19), respectively, while the score of social support was(37.08 ± 8.14). The results of multiple linear regression analysis showed that the scores of adaptability to return -to -work of patients with undergraduate and master's degree education increased by 1.063 and 1.156, respectively, compared with patients with junior college degrees and/or below. Compared with patients who underwent mastectomy, the score of adaptability to return -to -work of patients undergoing breast-conserving surgery increased by 2.136 points, and that of front-line teachers decreased by 2.001 points compared with administrative patients. Compared with patients in public education institutions, the scores of adaptability to return-towork of patients in private education institutions decreased by 2.249 points. When the scores of FoP -Q -SF and SSRS increased by 1 point, the scores of adaptability to return-to-work increased by -1.241 and 1.456 points, respectively. All differences were statistically significant (P < 0.01). Conclusions The female teachers' level of adaptability to return-to - work after breast cancer surgery in Xinjiang needs to be improved, and the relevant departments should pay attention to the care and social support for female teachers with low educational levels, with mastectomy, in front-line teaching posts, or in private educational institutions, so as to improve their adaptability to return to work. [ABSTRACT FROM AUTHOR]

ObjectiveTo explore the prevalence and main influencing factors of fear of disease progression (FoP) in Chinese cancer survivors and to provide references for the prevention and control of mental health problems in cancer patients. MethodsWe searched Chinese National Knowledge Infrastructure (CNKI), China Biomedical Database (CBM), Wanfang Database, Weipu Chinese Science Database and Technology Periodical Database (VIP), PubMed, Cochrane Library Database, Web of Science Database, Embase Database, PsycINFO Database, and CINAHL Database to retrieve literatures on the prevalence and influencing factors of FoP in Chinese cancer survivors published up to August 31, 2021. Stata MP 16.0 software was used to perform a meta-analysis. ResultsFinally, 22 literatures (19 in Chinese and 3 in English) were included in the analysis, with a total of 6 461 participants. The meta-analysis results showed that the prevalence of FoP in Chinese cancer survivors was 51.0% (95% confidence interval [95% CI ]: 42.0% – 61.0%). The results of subgroup analysis revealed that the prevalence of FoP differed significantly among cancer survivors in different regions (χ2 = 843.3, P < 0.05 ), with the prevalence rates of 56.0%, 54.0% and 42.0% for cancer survivors in South, Central and East China; the prevalence also varied among the survivors suffering from cancer of various systems (χ2 = 843.3, P < 0.05 ) and the prevalence rate was 40.0%, 56.0%, 58.0% and 54.0% for the survivors with digestive tract, gynecological, hematological and respiratory malignancies, respectively. The meta-analysis revealed that age, average monthly income, clinical stage of the malignancy, educational level, marital status, employment, disease course, family history of cancer, and anxiety were influencing factors for FoP among the survivors. The results of meta-regression analysis demonstrated that the sources of heterogeneity of the included studies were associated with following characteristics of the survivors: aged < 40 years ( β = 4.29, P = 0.018 ), monthly income of 1 000 – 2 999 (RMB yuan, β = – 3.80, P = 0.032 ), monthly income of 3 000 – 4 999 ( β = – 4.56, P = 0.011 ), monthly income of ≥ 5 000 ( β = – 8.70, P = 0.000 ), and with the malignancy of clinical stage I ( β = – 5.55,P = 0.020 ). Sensitivity analysis indicated that the results of the meta-analysis were stable; the results of Egger′ test and funnel plot demonstrated that the publication bias was less likely to present for the studied indicators, except for family history. ConclusionThe prevalence of FoP is relatively high among Chinese cancer survivors and the prevalence varies among survivors living in different regions and with different clinical stage of the malignancy; the FoP prevalence is mainly influenced by survivors′ age, monthly income, clinical stage of the malignancy, education, marital status, employment, disease course, family history of malignancy, and anxiety symptom.

Objective To explore the relationship between mental health level and chronic disease in patients with COVID-19.Methods A total of 359 COVID-19 infected persons aged 18 years old and above from December 15,2022 to December 31,2022 in Chongqing were selected as study subjects by convenience sampling method. Basic information questionnaire, SCL-90 Symptom Checklist and Simplified Fear Disease Progression Scale were used to conduct a questionnaire survey. The subjects were divided into the chronic disease group and the non-chronic disease group, and the mental health level of the two groups was compared. Results There were significant differences in age and gender between the two groups（P＜0.05）.There was no significant difference in the score of fear disease progression（P＞0.05）.There were significant differences in SCL-90 scores and scores of each dimension（P＜0.05）.Conclusion The mental health level of COVID-19 patients with chronic diseases is worse than that of those without chronic diseases. Medical staff can pay more attention to strengthen psychological counseling for people with chronic diseases to reduce the level of fear of disease progression. [ABSTRACT FROM AUTHOR]

Objective To investigate the mediating role of self⁃representation in alexithymia and fear of disease progression in patients with nasopharyngeal carcinoma. Methods A total of 241 patients with nasopharyngeal carcinoma, who attended the Department of Medical Oncology of the First Affiliated Hospital of Guangxi Medical University from December 2020 to June 2021, were selected as the research objects. The distress disclosure index (DDI), the Toronto alexithymia scale (TAS) and the fear of progression questionnaire⁃ short form (FoP⁃Q⁃SF) were used to analyze the correlation between the alexithymia, self⁃representation and the fear of disease progression in patients with nasopharyngeal carcinoma, and to analyze the mediating role of self ⁃ representation in alexithymia and fear of disease progression. Result The total scores of self ⁃ representation, fear of disease progression and alexithymia were (29.39 ± 8.26) points, (34.51±5.68) points and (54.67±8.91) points, respectively, in patients with nasopharyngeal carcinoma. The results of Pearson correlation analysis showed that the total scores of alexithymia was negatively correlated with self⁃representation (P<0.001), and positively correlated with fear of disease progression (P<0.001). Self⁃representation was negatively correlated with fear of disease progression (P<0.001). The results of mediation analysis showed that there was a partial mediating effect of self⁃representation between alexithymia and fear of disease progression (the mediating effect accounted for 21.6%). Conclusions Patients with nasopharyngeal carcinoma are less willing to self⁃representation, and alexithymia and fear of disease progression need to be improved. Alexithymia can have an impact on patients' fear of disease progression through the mediation of self⁃representation. [ABSTRACT FROM AUTHOR]

To characterize patterns of psychological resilience in gastric cancer survivors using latent profile analyses and to explore the factors influencing these latent profiles based on Kumpfer's resilience framework. Five hundred eighty-six gastric cancer survivors were recruited between July 30, 2021, and May 1, 2023. A demographic and clinical characteristics questionnaire, Connor and Davidson's Resilience Scale (CD-RISC), Fear of Progression Questionnaire Short Form (FoP-Q-SF), General Self-efficacy Scale (GSES), Medical Coping Modes Questionnaire (MCMQ), and Social Support Rating Scale (SSRS) were used for the investigation. Latent profile analysis of the resilience of gastric cancer survivors was conducted, and the factors influencing the latent profiles were explored by multivariate logistic regression analysis. A total of 586 questionnaires were collected, and 572 were valid, with an effective recovery rate of 97.61%. The results of latent profile analysis showed that the resilience of gastric cancer survivors was divided into four subgroups, namely, the low-resilience group (18.4%), moderate-resilience group (43.2%), medium-high-resilience group (30.2%), and high-resilience group (8.2%). Multivariate logistic regression analysis showed that fear of disease progression, self-efficacy, medical coping mode and social support were influencing factors of subgroups. Psychological resilience in gastric cancer survivors is individualized. Nurses should assess risk and protective factors for survivor resilience based on Kumpfer's resilience framework, identify unique needs, and develop new approaches and interventions. • Resilience in gastric cancer survivors has individual characteristics. • Four latent profiles of resilience are identified in gastric cancer survivors. • High fear of progression and low self-efficacy are present in the low-resilience group of patients. • Patients in the high-resilience group have high social support and tend to choose confrontational coping. • Psychological interventions should be tailored according to the resilience characteristics of different subgroups. [ABSTRACT FROM AUTHOR]

Objective: To explore the mediating effect of shame in patients with malignant haematological diseases between fear of disease progression and social alienation., Methods: Recruiting 310 patients with haematological malignancies as the research population, the convenience sampling method was used to investigate the general information questionnaire, the fear of disease progression scale, the social influence scale and the general alienation scale., Results: The patients with haematological malignancies scored (36.02 ± 9.74) points for fear of disease progression, (58.02 ± 9.52) points for stigma and (31.31 ± 5.85) points for social alienation. Social alienation in patients with haematologic malignancies was positively correlated with stigma (r = 0.500, P  < 0.01) and fear of disease progression (r = 0.424, P  < 0.01), and fear of disease progression was also positively correlated with stigma (r = 0.405, P  < 0.01). Bootstrap test results showed that the mediating effect of stigma on the relationship between fear of disease progression and social alienation in patients with haematological malignancies was 0.159, accounting for 37.5% of the total effect., Conclusion: The sense of shame plays an intermediary role between fear of disease progression and social alienation in patients with malignant haematological diseases. Clinical nurses should pay attention to the current situation of fear and shame in patients with such diseases and take appropriate intervention measures to reduce the occurrence of negative emotions such as social alienation.

Background & Aim: Feeling of low self-efficacy in management of pain and fear of disease progression are some of the problems that necessitates the need for psychological services for people with migraine headaches. Therefore, this study aimed to determine the effect of metacognitive therapy on the self-efficacy of pain and fear of disease progression in nurses with migraine headaches. Materials and Methods: This quasi-experimental research had a pretest-posttest design and a control group and was carried out all nurses with migraine in Tabriz, Iran during 2018-2019. In total, 30 individuals who were diagnosed with the disease based on ICHD-3 criteria and by receiving a score higher than standard deviation in the migraine headache symptom questionnaire were selected by purposive sampling and randomly assigned to experimental and control groups of 15 participants. The groups completed the pain self-efficacy questionnaire by Nicholas (1989) and fear of progression questionnaire by Herschbach (2011) as a pre-test and post-test. Group metacognitive therapy was performed in 10 sessions of 60 minutes (two sessions weekly for five weeks) in the experimental group while the control group received no intervention. Data analysis was performed in SPSS version 23 using multivariate and univariate covariance analysis. Results: According to the results of covariance analysis, the metacognitive therapy had a significant effect on the increase of self-efficacy of pain and reduce of fear of disease progression in nurses with migraine headaches. Conclusion: Considering that metacognitive therapy was effective in increasing the self-efficacy of pain and reducing the fear of progression in nurses with migraine headache, it is recommended that this therapeutic approach be considered as an effective interventional method at the hospital level.

Objective: To investigate the status quo of fear of disease progression in postoperative patients' spouse of bladder cancer and analyze its influencing factors. Methods: Postoperative patients' spouse of bladder cancer of a cancer hospital in Tianjin were selected as the research objects by the convenience sampling method. The general data questionnaire, spouse fear of disease progression scale and self-efficacy scale were used to investigate. Multiple linear regression was used to analyze the influencing factors of the fear of the disease progression in the postoperative patients' spouse of bladder cancer. Results: The score of fear of disease progression was (35.75 ± 9.86). The results of multiple linear regression analysis showed that the spouse's age, medical payment method, occupational status and self-efficacy were the main influencing factors for the spouse's fear of disease progression after bladder cancer (P < 0.05), which accounted for 55% of the total variation. Conclusion: The spouse's fear of disease progression in patients with bladder cancer is at a moderate level, and age, medical payment method, occupational status and self-efficacy are the main influencing factors. It is suggested that clinical medical staff focus on young, rural cooperative medical care, self-financed, in-service, and unemployed, low self-efficacy of postoperative bladder cancer patients' spouses. A series of psychological counseling and health education should be given to help the patient spouse correctly understand and deal with diseases, reduce the patients' spouses of negative emotions, improve the patients' spouses of self-efficacy, and reduce the spouse fear level of disease progression. [ABSTRACT FROM AUTHOR]

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Objective: Prior to hematopoietic stem cell transplantation (HSCT), and despite the high objective risks associated with HSCT, fear of progression (FoP) has only sparsely been studied in patients with acute leukemia until now. The aim of this study was the assessment of the prevalence of FoP, and any relevant correlates and typical concerns.Methods: We included 59 adult patients with acute leukemia who were tested prior to their first HSCT during an in-patient stay. Patients completed self-report measures assessing FoP (Fear of Progression Questionnaire-Short Form, FoP-Q-SF) and relevant correlates of FoP (eg, patients' physical state, depression, psychosocial distress, or social support).Results: About one third of the patients (35.6%; n = 21) had high FoP. Higher FoP was associated with previous cancer diagnosis, as well as depression, anxiety, reduced physical functioning, lower mental health-related quality of life, and lower positive social support. The greatest fears reported by these patients reflected common fears of cancer patients (eg, fear about leaving their families behind), but also specific fears related to the current situation (eg, fear of severe medical treatments during the course of the illness).Conclusions: This was the first study providing an extensive analysis of FoP in leukemia patients prior to the extreme situation of HSCT. FoP is frequent and of major clinical importance for these patients. Hence, we recommend that patients undergo routine screening for FoP, to identify highly distressed patients at an early stage, and to offer targeted support. [ABSTRACT FROM AUTHOR]

BACKGROUND AND OBJECTIVE: Fear of disease progression and rejection of what happened and not being able to distinguish oneself from mental processes cause confusion in mental health. Since acceptance and commitment therapy emphasizes on modification of dysfunctional processes such as avoidance and fusion and their change to acceptance and commitment, the present study was conducted to examine the effectiveness of acceptance and commitment therapy on self-differentiation and fear of disease progression in patients with breast cancer. METHODS: This clinical trial was performed on 30 patients referred to the Touba Oncology Center in Sari, who were randomly divided into two groups of experiment and control (n=15). The treatment was performed in eight 90-minute sessions in the experimental group. Participants were assessed and compared based on questionnaire of selfdifferentiation and fear of disease progression before the experiment and two months after that. FINDINGS: The results showed that fear of disease progression in the pre-test compared to the post-test decreased in the experimental group (135.11±4.27 versus 126.05±3.12) and in the follow-up period, this decease continued in the experimental group (125.32±3.05) (p<0.05). In addition, the mean score of self-differentiation in pre-test compared to post-test increased (67.12±12.5 versus 77.17±4.51) and this increase continued in the follow-up period (75.4±3.34) (p<0.05). CONCLUSION: The results of the study showed that acceptance and commitment therapy management could be effective in increasing self-differentiation and reducing the fear of disease progression in breast cancer patients. [ABSTRACT FROM AUTHOR]

Fear of disease progression is one of the most common sources of psychological distress in patients suffering from chronic diseases. Fear of disease progression is a situationspecific and fully discernible (reportable) emotion based on personal experience of a life-threatening disease. This article presents the results of a study of cancer patients’ coping behavior according to the levels of fear of disease progression experienced. The presence of pronounced fear of disease progression reflects a negative cognitive-affective response to one’s expectations for one’s own future; this response is related to a decrease in adaptive capacity. To determine the particular characteristics of coping strategies and coping resources in women with reproductive-system cancers according to the level of fear of disease progression. A total of 177 women with reproductive-system cancers were examined, among them 59 with breast cancer and 118 with gynecological cancers. Women with reproductive-system cancers have varying sets of coping strategies and coping resources according to their level of fear of disease progression. For each of the differentiated groups, specific characteristics of the strategies of coping with difficult life situations are described, along with cognitive self-regulation strategies specific to the illness and to coping resources. The women exhibiting moderate fear of disease progression significantly more often adhered to problem-oriented strategies of coping with difficult life situations and illness and had an internal locus of control regarding treatment. Patients with a low level of fear of disease progression tended to use strategies of positive reinterpretation of difficult life situations and illness; an external locus of control regarding treatment prevailed in this group. Patients found to have a dysfunctional level of fear of disease progression displayed significantly higher rates of using cognitive-regulation strategies focused on negative aspects of illness, as well as strategies for avoiding difficult life situations. Fear of disease progression is a psychological problem in women with reproductive-system cancers. Higher levels of fear of disease progression are associated with a decrease in the psychosocial adaptation of women suffering from reproductivesystem cancers.

Objective: Fear of progression (FOP) is a prevalent concern among breast cancer patients that affect their adjustment to disease. This study examined whether self-efficacy moderates the effect of illness perception (IP) on FOP and whether the moderating effect of self-efficacy depends on the level of depressive symptoms.Methods: A cross-sectional survey including brief illness perception questionnaire (BIPQ), FOP short form, general self-efficacy scale, and the center for epidemiologic studies depression scale were administered to 245 patients with breast cancer in Korea.Results: Self-efficacy moderated the negative impact of the patients' perception of chronic timeline and a greater emotional impact of the illness on FOP. However, the moderating effect of self-efficacy of the BIPQ timeline and emotions on FOP depended on level of depressive symptoms.Conclusions: The findings underscore the importance of considering the IP as determinants of FOP, as well as of self-efficacy and depression as the moderating factors in the relationship between IP and FOP, suggesting the need to enhance self-efficacy and depressive symptoms in order to compensate the negative impact of IP on FOP in breast cancer patients. [ABSTRACT FROM AUTHOR]

Purpose: Most patients with well-differentiated thyroid cancer (WDTC) have favorable prognosis and survive for many years. We investigated the effect of thyroid cancer surgery on subsequent psychological aspects. Methods: Demographic parameters, clinical characteristics, and other data were obtained from self-administered questionnaires administered to WDTC patients at various times after thyroid cancer surgery. The questionnaires assessed psychological aspects based on three scales: a performance of everyday activities questionnaire developed for this study, the Hospital Anxiety and Depression Scale (HADS), and the Fear of Progression Questionnaire (FoP-Q). Results: The mean time since thyroid surgery and the survey was 3.5 years. More than half of the patients (60.7%) were able to perform all activities without limitations. The HADS scores indicated no anxiety or depression in most patients, and the FoP-Q scores indicated little fear of cancer progression. The time since surgery, type of surgery, use of postoperative radioiodine ablative therapy, and recurrence or metastasis had no significant effect on the psychological scores. Conclusions: Our study indicates that most WDTC patients are psychologically stable after the thyroid cancer surgery. [ABSTRACT FROM AUTHOR]

Background: Lung cancer has the highest incidence rate and mortality rate of all malignancies. In recent years, the therapeutic effect of lung cancer has been greatly improved, but the fear of disease progression still directly affects the quality of life (QOL) of patients. The aim of this study was to evaluate the factors affecting the progression of fear of disease and its impact on the quality of life in patients with lung cancer., Methods: From December 2019 to February 2020, 102 patients with lung cancer in the Department of Thoracic Oncology of a top three hospital were investigated by using the simplified fear of disease progression scale (FoP-Q-SF) and the quality-of-life scale for cancer patients (FACT-G). Data were collected and statistically analyzed by SPSS25.0 software., Results: A total of 110 questionnaires were distributed and 102 valid questionnaires were recovered, indicating a recovery rate of 92.7%. The results of multiple stepwise regression analyses showed that blood group, monthly income, and mood state were the influencing factors for the progression of phobic diseases in cancer patients (P<0.05), and the score of progression of phobic disease was negatively correlated with the quality-of-life score (r=-0.382)., Conclusions: The progress of phobic diseases in patients with lung cancer seriously affects their QOL, and further attention by medical staff in providing health education, psychological counseling, social support, and other measures is required.