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21. Evaluation of the Effect of Nano-Hydroxyapatite Versus Nano-Hydroxyapatite 3D Scaffold Membrane on Osseointegration's Quality of Dental Implants (Radiographic and Histopathological Experimental Study).

Author

Fayed, Heba Mohamed, Eid, Sherif, Yassin, Hala, Fathy, Shereen, El-din, Yasmine Alaa, Elkamary, Yasser Mohamed Helmy, and Ahmed, Waheed Abdelhamid

Subjects
DENTAL implants, OSSEOINTEGRATION, BONE substitutes, BONE grafting, OSSEOINTEGRATED dental implants, COMPACT bone, BONE density
Abstract

Innovation in biomaterials is always of interest in the medical field; with emergence of nano technology which enhanced biocompatibility and bioactivity of such materials are of great benefit. Nano technology treatment with biomaterials, bone graft substitutes and 3D scaffold membrane could be further utilized to enhance osseointegration, success, and survival of dental implants. Evaluation of new bone formation around implants in rabbit's tibias supplemented by 3D scaffold membranes and nano-hydroxyapatite (nHA) radiographically and histopathologically. A total of 24 dental implants were placed in 12 rabbit's tibiae which was assigned to Groups 1, 2 and 3. G1=implant as control group, G2=implant +bone Graft, G3=G2+membrane according to the material. Animals were euthanized after zero and 2 months. Radiographs were obtained at time of implant surgery and after 2 months. Bone quality was evaluated between the three groups radiographically, & histopathologically. Results revealed preferences of G3 formed bone quality than G2 and G1. Radiographic results of G3 revealed best bone osteointegration over the other groups. In addition, the histopathological results revealed better osteointegration with formation of thick lamellar compact bone when using combination of nHA bone graft and 3D scaffoled membrane than other groups. Within the limitations of this study, results demonstrated that nHA with 3D scaffold membrane has a high potential in application as an adjunctive bone substitute, improving the osteointegration and may influence bone density and quality around dental implants. [ABSTRACT FROM AUTHOR]

Published
2023

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