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150 results on '"Favilla, S."'

1. A retrospective, multicenter study on the management of macular holes without residual internal limiting membrane: the refractory macular hole (ReMaHo) study

Author

Lorenzi, U., Mehech, J., Caporossi, T., Romano, M. R., De Fazio, R., Parrat, E., Matonti, F., Mora, P., Sborgia, G., Forlini, M., Ventre, L., Soler, V., Sampo, M., Fiore, T., Van Overdam, K., Guigou, S., Rouhette, H., Rapizzi, E., Denion, E., Rebollo, O., Meyer, F., Uzzan, J., Mafrici, M., Bacherini, D., Favilla, S., Ricciotti, G., Tedesco, S. A., Gandolfi, S., and Muraine, M.

Subjects
Visual Acuity, Retinal Perforations, Sensory Systems, Basement Membrane, Retina, Cellular and Molecular Neuroscience, Ophthalmology, No internal limiting membrane, Vitrectomy, Reconstructive surgery, Humans, Full thickness macular hole, Prognostic variables, Tomography, Optical Coherence, Retrospective Studies
Abstract

Purpose To evaluate the surgical management, outcomes and prognostic factors of full thickness macular holes without residual internal limiting membrane (NO-ILM FTMHs). Methods We performed a multicenter, retrospective study of 116 NO-ILM FTMHs. Human amniotic membrane (hAM) plug, autologous ILM free flap transplantation (AILMT), and autologous retinal graft transplantation (ART) were performed in 58, 48, and 10 patients, respectively. Data were collected before and up to 12 months after surgery. The primary outcomes were hole closure and final best-corrected visual acuity (BCVA). Results The final BCVA (0.78 ± 0.51 logMAR) was significantly better than and correlated with the initial BCVA (p 680 μm had a higher closure rate with hAM than with AILMT (p = 0.02). Conclusions AILMT and hAM were the most frequently performed surgeries with both high closure rate and significant functional improvement. Preoperative BCVA was correlated with final BCVA. The minimum FTMH diameter may guide the treatment choice.

Published
2022

8. Touch screen collaborative music: designing NIME for older people with dementia

Author

Swinburne University of Technology. Faculty of Health, Arts and Design, Favilla, S., Pedell, S., Swinburne University of Technology. Faculty of Health, Arts and Design, Favilla, S., and Pedell, S.

Abstract

This paper presents new touch-screen collaborative music interaction for people with dementia. The authors argue that dementia technology has yet to focus on collaborative multi-user group musical interactions. The project aims to contribute to dementia care while addressing a significant gap in current literature. Two trials explore contrasting musical scenarios: the performance of abstract electronic music and the distributed performance of J.S. Bach's Goldberg Variations. Findings presented in this paper; demonstrate that people with dementia can successfully perform and engage in collaborative music performance activities with little or no scaffolded instruction. Further findings suggest that people with dementia can develop and retain musical performance skill over time. This paper proposes a number of guidelines and design solutions.

Published
2014

38. Endothelial dysfunction and oxidative stress in chronic renal failure

Author

Ghiadoni, L., ADAMASCO CUPISTI, Huang, Y., Mattei, P., Cardinal, H., Favilla, S., Rindi, P., Barsotti, G., Taddei, S., and Salvetti, A.

Subjects
Adult, Male, Brachial Artery, Ascorbic Acid, Kidney Function Tests, Risk Assessment, Severity of Illness Index, Sampling Studies, Reference Values, Renal Dialysis, Humans, Erythropoietin, Antihypertensive Agents, Aged, Middle Aged, Recombinant Proteins, Epoetin Alfa, Vasodilation, Oxidative Stress, Treatment Outcome, Case-Control Studies, Disease Progression, Kidney Failure, Chronic, Female, Endothelium, Vascular, Follow-Up Studies
Abstract

Uremic patients have an increased incidence of cardiovascular disease (CVD), endothelial dysfunction and oxidative stress that can contribute to cardiovascular (CV) events. To assess the relationship between endothelial dysfunction, oxidative stress and renal failure severity, we studied 40 patients (age 57 +/- 7 yrs, 24 males) affected by chronic kidney disease (CKD) K/DOQI stage 3-5 (serum creatinine (Cr) 5.6 +/- 2.2 mg/dL) on conservative treatment, 20 uremic patients (age 57 +/- 12 yrs, 13 males) on hemodialysis (HD) and 30 healthy controls (56 +/- 12 yrs, 20 males). Before and 2 hr after oral vitamin C (2 g) administration, we measured brachial artery endothelium-dependent vasodilation (flow mediated dilation (FMD)) to reactive hyperemia following 5 min of forearm ischemia and the response to sublingual glyceril trinitrate (GTN). Measurements were made by high-resolution ultrasound and computerized analysis. FMD was lower in CKD patients than in controls (5.3 +/- 2.2 vs. 6.9 +/- 2.8%; p0.01) and was further reduced in HD patients (3.6 +/- 2.7; p0.01 vs. CKD patients). Response to GTN was similar in all groups. FMD was related to Cr clearance (r=0.42; p0.01) in CKD patients, while it related inversely to Kt/V(urea) (r=-0.52; p0.05) in HD patients. After vitamin C administration, FMD was significantly enhanced in HD (4.7 +/- 2.4%; p0.01 vs. baseline), but not in CKD patients. Response to GTN was unaffected. However, vitamin C load reduced oxidative stress markers, and increased plasma antioxidant capability in both groups. In conclusion, the reduced endothelium-dependent dilation in the brachial artery of CKD patients is related to renal failure severity. HD patients showed a more marked alteration, which seems to be related, at least in part, to increased oxidative stress.

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