340 results on '"Favier, M."'
Search Results
2. Demonstration of Ramsey-Comb Precision Spectroscopy in Xenon at Vacuum Ultraviolet Wavelengths Produced with High-Harmonic Generation
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Dreissen, L. S., Roth, C., Gründeman, E. L., Krauth, J. J., Favier, M. G. J., and Eikema, K. S. E.
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Physics - Atomic Physics - Abstract
The remarkable progress in the field of laser spectroscopy induced by the invention of the frequency-comb laser has enabled many new high-precision tests of fundamental theory and searches for new physics. Extending frequency-comb based spectroscopy techniques to the vacuum (VUV) and extreme ultraviolet (XUV) spectral range would enable measurements in e.g. heavier hydrogen-like systems and open up new possibilities for tests of quantum electrodynamics and measurements of fundamental constants. The main approaches rely on high-harmonic generation (HHG), which is known to induce spurious phase shifts from plasma formation. After our initial report (Physical Review Letters 123, 143001 (2019)), we give a detailed account of how the Ramsey-comb technique is used to probe the plasma dynamics with high precision, and enables accurate spectroscopy in the VUV. A series of Ramsey fringes is recorded to track the phase evolution of a superposition state in xenon atoms, excited by two up-converted frequency-comb pulses. Phase shifts of up to 1 rad induced by HHG were observed at ns timescales and with mrad-level accuracy at $110$ nm. Such phase shifts could be reduced to a negligible level, enabling us to measure the $5p^6 \rightarrow 5p^5 8s~^2[3/2]_1$ transition frequency in $^{132}Xe$ at 110 nm (seventh harmonic) with sub-MHz accuracy. The obtained value is $10^4$ times more precise than the previous determination and the fractional accuracy of $2.3 \times 10^{-10}$ is $3.6$ times better than the previous best spectroscopic measurement using HHG. The isotope shifts between $^{132}Xe$ and two other isotopes were determined with an accuracy of $420$ kHz. The method can be readily extended to achieve kHz-level accuracy, e.g. to measure the $1S-2S$ transition in $He^+$. Therefore, the Ramsey-comb method shows great promise for high-precision spectroscopy of targets requiring VUV and XUV wavelengths.
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- 2021
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3. Accurate laser frequency locking to optical frequency combs under low-signal-to-noise-ratio conditions
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Guo, C., Favier, M., Galland, N., Cambier, V., Álvarez-Martínez, H., Lours, M., De Sarlo, L., Andia, M., Targat, R. Le, and Bize, S.
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Physics - Optics ,Physics - Atomic Physics - Abstract
We demonstrate a method for accurately locking the frequency of a continuous-wave laser to an optical frequency comb in conditions where the signal-to-noise ratio is low, too low to accommodate other methods. Our method is typically orders of magnitude more accurate than conventional wavemeters and can considerably extend the usable wavelength range of a given optical frequency comb. We illustrate our method by applying it to the frequency control of a dipole lattice trap for an optical lattice clock, a representative case where our method provides significantly better accuracy than other methods., Comment: 13 pages, 7 figures, 24 references
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- 2020
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4. High-Precision Ramsey-Comb Spectroscopy Based on High-Harmonic Generation
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Dreissen, L. S., Roth, C., Gründeman, E. L., Krauth, J. J., Favier, M., and Eikema, K. S. E.
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Physics - Atomic Physics - Abstract
High-harmonic generation (HHG) is widely used for up-conversion of amplified (near) infrared ultrafast laser pulses to short wavelengths. We demonstrate that Ramsey-comb spectroscopy, based on two such pulses derived from a frequency-comb laser, enables us to observe phase effects in this process with a few mrad precision. As a result, we could perform the most accurate spectroscopic measurement based on light from HHG, illustrated with a determination of the $5p^6 \rightarrow 5p^5 8s~^2[3/2]_1$ transition at 110 nm in $^{132}$Xe. We improve its relative accuracy $10^4$ times to a value of $2.3\times10^{-10}$. This is 3.6 times better than shown before involving HHG, and promising to enable $1S-2S$ spectroscopy of He$^+$ for fundamental tests.
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- 2019
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5. Laser Trapping of Circular Rydberg Atoms
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Cortiñas, R. G., Favier, M., Ravon, B., Méhaignerie, P., Machu, Y., Raimond, J. M., Sayrin, C., and Brune, M.
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Physics - Atomic Physics ,Quantum Physics - Abstract
Rydberg atoms are remarkable tools for quantum simulation and computation. They are the focus of an intense experimental activity mainly based on low-angular-momentum Rydberg states. Unfortunately, atomic motion and levels lifetime limit the experimental time-scale to about 100$\mu$s. Here, we demonstrate laser trapping of long-lived circular Rydberg states for up to 10ms. Our method is very general and opens many opportunities for quantum simulation. The 10ms trapping time corresponds to thousands of interaction cycles in a circular-state-based quantum simulator. It is also promising for quantum metrology and quantum information with Rydberg atoms.
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- 2019
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6. Paving the way for fundamental physics tests with singly-ionized helium
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Krauth, J. J., Dreissen, L. S., Roth, C., Gründeman, E. L., Collombon, M., Favier, M., and Eikema, K. S. E.
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Physics - Atomic Physics - Abstract
High-precision laser spectroscopy of atomic hydrogen has led to an impressive accuracy in tests of bound-state quantum electrodynamics (QED). At the current level of accuracy many systematics have to be studied very carefully and only independent measurements provide the ultimate cross-check. This has been proven recently by measurements in muonic hydrogen, eventually leading to a significant shift of the CODATA recommended values of the proton charge radius and the Rydberg constant. We aim to contribute to tests of fundamental physics by measuring the 1S-2S transition in the He$^+$ ion for the first time. Combined with measurements in muonic helium ions this can probe the value of the Rydberg constant, test higher-order QED terms, or set benchmarks for ab initio nuclear polarizability calculations. We extend the Ramsey-comb spectroscopy method to the XUV using high-harmonic generation in order to excite a single, trapped He$^+$ ion., Comment: 10 pages, 4 figures, FFK2019
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- 2019
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7. Search for transient variations of the fine structure constant and dark matter using fiber-linked optical atomic clocks
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Roberts, B. M., Delva, P., Al-Masoudi, A., Amy-Klein, A., Bærentsen, C., Baynham, C. F. A., Benkler, E., Bilicki, S., Bize, S., Bowden, W., Calvert, J., Cambier, V., Cantin, E., Curtis, E. A., Dörscher, S., Favier, M., Frank, F., Gill, P., Godun, R. M., Grosche, G., Guo, C., Hees, A., Hill, I. R., Hobson, R., Huntemann, N., Kronjäger, J., Koke, S., Kuhl, A., Lange, R., Legero, T., Lipphardt, B., Lisdat, C., Lodewyck, J., Lopez, O., Margolis, H. S., Álvarez-Martínez, H., Meynadier, F., Ozimek, F., Peik, E., Pottie, P. -E., Quintin, N., Sanner, C., De Sarlo, L., Schioppo, M., Schwarz, R., Silva, A., Sterr, U., Tamm, Chr., Targat, R. Le, Tuckey, P., Vallet, G., Waterholter, T., Xu, D., and Wolf, P.
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Astrophysics - Cosmology and Nongalactic Astrophysics ,High Energy Physics - Phenomenology ,Physics - Atomic Physics - Abstract
We search for transient variations of the fine structure constant using data from a European network of fiber-linked optical atomic clocks. By searching for coherent variations in the recorded clock frequency comparisons across the network, we significantly improve the constraints on transient variations of the fine structure constant. For example, we constrain the variation in alpha to <5*10^-17 for transients of duration 10^3 s. This analysis also presents a possibility to search for dark matter, the mysterious substance hypothesised to explain galaxy dynamics and other astrophysical phenomena that is thought to dominate the matter density of the universe. At the current sensitivity level, we find no evidence for dark matter in the form of topological defects (or, more generally, any macroscopic objects), and we thus place constraints on certain potential couplings between the dark matter and standard model particles, substantially improving upon the existing constraints, particularly for large (>~10^4 km) objects.
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- 2019
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8. From the original SARS-CoV-2 strain to the Omicron variant: Predictors of COVID-19 in ambulatory symptomatic children
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Cohen, R., Rybak, A., Ouldali, N., Angoulvant, F., Béchet, S., Gajdos, V, Hau, I., Sellam, A., El Aouane El Ghomari, I., Elmerich, F., Batard, C., Auvrignon, A., Grimprel, E., Favier, M., Jung, C., and Levy, C.
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- 2022
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9. Factors associated with hospital admission and adverse outcome for COVID-19: Role of social factors and medical care
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Beaumont, A.-L., Vignes, D., Sterpu, R., Bussone, G., Kansau, I., Pignon, C., Ben Ismail, R., Favier, M., Molitor, J.-L., Braham, D., Fior, R., Roy, S., Mion, M., Meyer, L., Andronikof, M., Damoisel, C., Chagué, P., Aurégan, J.-C., Bourgeois-Nicolaos, N., Guillet-Caruba, C., Téglas, J.-P., and Abgrall, S.
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- 2022
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10. Evaluation des performances du test antigénique combiné VRS / Grippe / SARS-CoV-2 AAZ All In Triplex® aux urgences pédiatriques
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Zemali, N., primary, Mazarguil, L., additional, Favier, M., additional, Bailhache, M., additional, Poisvert, S., additional, Neau, M., additional, Lafon, M., additional, and Beauvieux, M., additional
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- 2024
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11. Comparing a mercury optical lattice clock with microwave and optical frequency standards
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Tyumenev, R, Favier, M, Bilicki, S, Bookjans, E, Targat, R Le, Lodewyck, J, Nicolodi, D, Coq, Y Le, Abgrall, M, Guéna, J, De Sarlo, L, and Bize, S
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Physics - Atomic Physics ,Physics - Optics ,Quantum Physics - Abstract
In this paper we report the evaluation of an optical lattice clock based on neutral mercury down to a relative uncertainty of $1.7\times 10^{-16}$. Comparing this characterized frequency standard to a Cs atomic fountain we determine the absolute frequency of the $^1S_0 \rightarrow \phantom{}^3P_0$ transition of $^{199}$Hg as $\nu_{\mathrm{Hg}} = 1 128\,575\,290\,808\,154.62\,$Hz $\pm\,0.19\,$Hz (statistical) $\pm\,0.38\,$Hz (systematic), limited solely by the realization of the SI second. Furthermore, by comparing the mercury optical lattice clock to a Rb atomic fountain, we determine for the first time to our knowledge the ratio between the $^{199}$Hg clock transition and the $^{87}$Rb ground state hyperfine transition. Finally we present a direct optical to optical measurement of the $^{199}$Hg/$^{87}$Sr frequency ratio. The obtained value of $\nu_{\mathrm{Hg}}/\nu_{\mathrm{Sr}}=2.629\,314\,209\,898\,909\,15$ with a fractional uncertainty of $1.8\times10^{-16}$ is in excellent agreement with the same measurement obtained by Yamanaka et al. (arXiv:1503.07941). This makes this frequency ratio one of the few physical quantities agreed upon by different laboratories to this level of uncertainty. Frequency ratio measurements of the kind of those reported in this paper have a strong impact for frequency metrology but also for fundamental physics as they can be used to monitor putative variations of fundamental constants., Comment: 23 pages, 12 figures, updated version including journal reference
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- 2016
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12. ESTRATEGIA DIDÁCTICA PARA LA ASIGNATURA SALUD ANIMAL CONSIDERADO LOS ESTILOS DE APRENDIZAJE DE LOS ESTUDIANTES
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LEYVA, J. P., primary, FAVIER, M. L., additional, SILVA, A. T. B., additional, and MENEZES, E. P., additional
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- 2022
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13. LA MOTIVACIÓN DEL APRENDIZAJE CON EL USO DEL ENTORNO VIRTUAL DE APRENDIZAJE
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LEYVA, J. P., primary, FAVIER, M. L., additional, SILVA, A. T. B., additional, and MENEZES, E. P., additional
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- 2022
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14. LOS ENTORNOS VIRTUALES DE APRENDIZAJE EN LA ASIGNATURA SALUD ANIMAL DE LA ESPECIALIDAD ZOOTECNIA – VETERINARIA
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LEYVA, J. P., primary, FAVIER, M. L., additional, SILVA, A. T. B., additional, and MENEZES, E. P., additional
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- 2022
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15. REVISIÓN BIBLIOGRÁFICA DE LOS ESTILOS DE APRENDIZAJE EN ENTORNOS VIRTUALES
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LEYVA, J. P., primary, FAVIER, M. L., additional, SILVA, A. T. B., additional, and MENEZES, E. P., additional
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- 2022
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16. ESTILOS DE APRENDIZAJE DE LOS ESTUDIANTES DE LA ESPECIALIDAD ZOOTECNIA - VETERINARIA
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LEYVA, J. P., primary, FAVIER, M. L., additional, SILVA, A. T. B., additional, and MENEZES, E. P., additional
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- 2022
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17. IMPLANTACIÓN DE UN ENTORNO VIRTUAL DE APRENDIZAJE EN EL INSTITUTO POLITÉCNICO AGROPECUARIO “MANUEL SIMÓN TAMEZ GUERRA”
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LEYVA, J. P., primary, FAVIER, M. L., additional, SILVA, A. T. B., additional, and MENEZES, E. P., additional
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- 2022
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18. Influence of pH on Oenococcus oeni metabolism: Can the slowdown of citrate consumption improve its acid tolerance?
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Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Eicher C; Tran T; Munier E; Coulon J; Favier M; Alexandre H; Reguant C; Grandvalet C, Bioquímica i Biotecnologia, Universitat Rovira i Virgili, and Eicher C; Tran T; Munier E; Coulon J; Favier M; Alexandre H; Reguant C; Grandvalet C
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Oenococcus oeni is the lactic acid bacteria most suited to carry out malolactic fermentation in wine, converting L-malic acid into L-lactic acid and carbon dioxide, thereby deacidifying wines. Indeed, wine is a harsh environment for microbial growth, partly because of its low pH. By metabolizing citrate, O. oeni maintains its homeostasis under acid conditions. Indeed, citrate consumption activates the proton motive force, helps to maintain intracellular pH, and enhances bacterial growth when it is co-metabolized with sugars. In addition, citrate metabolism is responsible for diacetyl production, an aromatic compound which bestows a buttery character to wine. However, an inhibitory effect of citrate on O. oeni growth at low pH has been highlighted in recent years. In order to understand how citrate metabolism can be linked to the acid tolerance of this bacterium, consumption of citrate was investigated in eleven O. oeni strains. In addition, malate and sugar consumptions were also monitored, as they can be impacted by citrate metabolism. This experiment highlighted the huge diversity of metabolisms between strains depending on their origin. It also showed the capacity of O. oeni to de novo metabolize certain end-products such as L-lactate and mannitol, a phenomenon never before demonstrated. It also enabled drawing hypotheses concerning the two positive effects that the slowing down of citrate metabolism could have on biomass production and malolactic fermentation occurring under low pH conditions.
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- 2024
19. Citrate metabolism in lactic acid bacteria: is there a beneficial effect for Oenococcus oeni in wine?
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Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Eicher, C; Coulon, J; Favier, M; Alexandre, H; Reguant, C; Grandvalet, C, Bioquímica i Biotecnologia, Universitat Rovira i Virgili, and Eicher, C; Coulon, J; Favier, M; Alexandre, H; Reguant, C; Grandvalet, C
- Abstract
Lactic acid bacteria (LAB) are Gram positive bacteria frequently used in the food industry for fermentation, mainly transformation of carbohydrates into lactic acid. In addition, these bacteria also have the capacity to metabolize citrate, an organic acid commonly found in food products. Its fermentation leads to the production of 4-carbon compounds such as diacetyl, resulting in a buttery flavor desired in dairy products. Citrate metabolism is known to have several beneficial effects on LAB physiology. Nevertheless, a controversial effect of citrate has been described on the acid tolerance of the wine bacterium Oenococcus oeni. This observation raises questions about the effect of citrate on the capacity of O. oeni to conduct malolactic fermentation in highly acidic wines. This review aims to summarize the current understanding of citrate metabolism in LAB, with a focus on the wine bacterium O. oeni. Metabolism with the related enzymes is detailed, as are the involved genes organized in cit loci. The known systems of cit locus expression regulation are also described. Finally, the beneficial effects of citrate catabolism on LAB physiology are reported and the negative impact observed in O. oeni is discussed.
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- 2024
20. High level software for 4.8 GHz LHC Schottky system
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Cai, J., McCrory, E., Pasquinelli, R., Favier, M., Jones, O. R., Lahey, T., and Jansson, A.
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Physics - Accelerator Physics - Abstract
The performance of the LHC depends critically on the accurate measurements of the betatron tunes. The betatron tune values of each LHC beam may be measured without excitation using a newly installed transverse Schottky monitor. A high-level software package written in Java has been developed for the Schottky system. The software allows end users to monitor and control the Schottky system, and provides them with non-destructive and continuous bunch-by-bunch measurements for the tunes, momentum spreads, chromaticities and emittances of the LHC beams. It has been tested with both proton and lead ion beams at the LHC with very successful results., Comment: 3 pp. Particle Accelerator, 24th Conference (PAC'11) 2011. 28 Mar - 1 Apr 2011. New York, USA
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- 2012
21. Array of Individual Circular Rydberg Atoms Trapped in Optical Tweezers
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Ravon, B., primary, Méhaignerie, P., additional, Machu, Y., additional, Hernández, A. Durán, additional, Favier, M., additional, Raimond, J. M., additional, Brune, M., additional, and Sayrin, C., additional
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- 2023
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22. ‘Still travelling’: Access to abortion post-12 weeks gestation in Ireland
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Grimes, L., Mishtal, J., Reeves, K., Chakravarty, D., Stifani, B., Chavkin, W., Duffy, D., Horgan, T., Favier, M., Murphy, M., Lavelanet, A.F., Grimes, L., Mishtal, J., Reeves, K., Chakravarty, D., Stifani, B., Chavkin, W., Duffy, D., Horgan, T., Favier, M., Murphy, M., and Lavelanet, A.F.
- Abstract
This article focuses on access to abortion in Ireland post-12 weeks gestational age. It critically examines abortion access under the legislative sections 9, 10 and 11 of the Health (Regulation of Termination of Pregnancy) Act 2018, the Multi-Disciplinary Team (MDT) process, as well as the appeals process in place. We highlight existing ambiguities in diagnosing and certifying cases of risk to health during pregnancy, particularly mental health, as well as the challenges in diagnosing and certifying cases of fatal fetal abnormality (FFA). The article incorporates service users' experiences in obtaining abortion in Ireland post-12 weeks, particularly in cases of FFA, and includes recommendations for policy and legislative change.
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- 2023
23. Experimental evolution forcing Oenococcus oeni acid tolerance highlights critical role of the citrate locus
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Universitat Rovira i Virgili, Julliat, F; Eicher, C; Tourti, N; Glaser, P; Cabanel, N; Coulon, J; Favier, M; Alexandre, H; Reguant, C; Guyot, S; Grandvalet, C, Universitat Rovira i Virgili, and Julliat, F; Eicher, C; Tourti, N; Glaser, P; Cabanel, N; Coulon, J; Favier, M; Alexandre, H; Reguant, C; Guyot, S; Grandvalet, C
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Oenococcus oeni is the main lactic acid bacterium associated with malolactic fermentation (MLF) of wines. MLF plays an important role in determining the final quality of wines. Nevertheless, due to the stressful conditions inherent to wine and especially acidity, MLF may be delayed. This study aimed to explore by adaptive evolution improvements in the acid tolerance of starters but also to gain a better understanding of the mechanisms involved in adaptation toward acidity. Four independent populations of the O. oeni ATCC BAA-1163 strain were propagated (approximately 560 generations) in a temporally varying environment, consisting in a gradual pH decrease from pH 5.3 to pH 2.9. Whole genome sequence comparison of these populations revealed that more than 45% of the substituted mutations occurred in only five loci for the evolved populations. One of these five fixed mutations affects mae, the first gene of the citrate operon. When grown in an acidic medium supplemented with citrate, a significantly higher bacterial biomass was produced with the evolved populations compared to the parental strain. Furthermore, the evolved populations slowed down their citrate consumption at low pH without impacting malolactic performance.
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- 2023
24. Post‐HCV cure self‐reported changes in physical activity, eating behaviours, and fatigue in people living with HIV (ANRS CO13 HEPAVIH)
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Marcellin, Fabienne, Di Beo, Vincent, Esterle, Laure, Abgrall, Sophie, Pialoux, Gilles, Barré, Tangui, Wittkop, Linda, Salmon‐ceron, Dominique, Sogni, Philippe, Carrieri, Patrizia, Roustant, F, Platterier, P, Kmiec, I, Traore, L, Lepuil, S, Parlier, S, Sicart‐payssan, V, Bedel, E, Anriamiandrisoa, S, Pomes, C, Mole, M, Bolliot, C, Catalan, P, Mebarki, M, Adda‐lievin, A, Thilbaut, P, Ousidhoum, Y, Makhoukhi, F.Z, Braik, O, Bayoud, R, Gatey, C, Pietri, M.P, Le Baut, V, Ben Rayana, R, Bornarel, D, Chesnel, C, Beniken, D, Pauchard, M, Akel, S, Lions, C, Ivanova, A, Ritleg, A‐s, Debreux, C, Chalal, L, Zelie, J, Hue, H, Soria, A, Cavellec, M, Breau, S, Joulie, A, Fisher, P, Gohier, S, Croisier‐bertin, D, Ogoudjobi, S, Brochier, C, Thoirain‐galvan, V, Le Cam, M, Chalouni, M, Conte, V, Dequae‐merchadou, L, Desvallees, M, Gilbert, C, Gillet, S, Knight, R, Lemboub, T, Michel, L, Mora, M, Protopopescu, C, Roux, P, Tezkratt, S, Ramier, C, Sow, A, Bureau, M, Trimoulet, P, Izopet, J, Serfaty, L, Paradis, V, Spire, B, Valantin, V., Chas, J, Zaegel‐faucher, O, Barange, K, Naqvi, A, Rosenthal, E, Bicart‐see, A, Bouchaud, O, Gervais, A, Lascoux‐combe, C, Goujard, C, Lacombe, K, Duvivier, C, Neau, D, Morlat, P, Bani‐sadr, F, Meyer, L, Boufassa, F, Autran, B, Roque, A.M, Solas, C, Fontaine, H, Costagliola, D, Piroth, L, Simon, A, Zucman, D, Boué, F, Miailhes, P, Billaud, E, Aumaître, H, Rey, D, Peytavin, G, Petrov‐sanchez, V, Levier, A, Usubillaga, R., Terris, B, Tremeaux, P, Katlama, C, Stitou, H, Cacoub, P, Nafissa, S, Benhamou, Y, Charlotte, F, Fourati, S, Poizot‐martin, I, Zaegel, O, Laroche, H, Tamalet, C, Callard, P, Bendjaballah, F, Amiel, C, Le Pendeven, C, Marchou, B, Alric, L, Metivier, S, Selves, J, Larroquette, F, Rio, V, Haudebourg, J, Saint‐paul, M.C, de Monte, A, Giordanengo, V, Partouche, C, Martin, A, Ziol, M, Baazia, Y, Iwaka‐bande, V, Gerber, A, Uzan, M, Garipuy, D, Ferro‐collados, M.J, Nicot, F, Yazdanpanah, Y, Adle‐biassette, H, Alexandre, G, Molina, J.M, Bertheau, P, Chaix, M.L, Delaugerre, C, Maylin, S, Bottero, J, Krause, J, Girard, P.M, Wendum, D, Cervera, P, Adam, J, Viala, C, Vittecocq, D, Quertainmont, Y, Teicher, E, Pallier, C, Lortholary, O, Rouzaud, C, Lourenco, J, Touam, F, Louisin, C, Avettand‐fenoel, V, Gardiennet, E, Mélard, A, Ochoa, A, Blanchard, E, Castet‐lafarie, S, Cazanave, C, Malvy, D, Dupon, M, Dutronc, H, Dauchy, F, Lacaze‐buzy, L, Desclaux, A, Bioulac‐sage, P, Reigadas, S, Lacoste, D, Bonnet, F, Bernard, N, Hessamfar, M, Paccalin, J.F, Martell, C, Pertusa, M.C, Vandenhende, M, Mercié, P, Pistone, T, Receveur, M.C, Méchain, M, Duffau, P, Rivoisy, C, Faure, I, Caldato, S, Bellecave, P, Tumiotto, C, Pellegrin, J.L, Viallard, J.F, Lazzaro, E, Greib, C, Majerholc, C, Brollo, M, Farfour, E, Polo Devoto, J, Kansau, I, Chambrin, V, Pignon, C, Berroukeche, L, Fior, R, Martinez, V, Favier, M, Deback, C, Lévy, Y, Dominguez, S, Lelièvre, J.D, Lascaux, A.S, Melica, G, Raffi, F, Allavena, C, Reliquet, V, Boutoille, D, Biron, C, Lefebvre, M, Hall, N, Bouchez, S, Rodallec, A, Le Guen, L, Hemon, C, Peyramond, D, Chidiac, C, Ader, F, Biron, F, Boibieux, A, Cotte, L, Ferry, T, Perpoint, T, Koffi, J, Zoulim, F, Bailly, F, Lack, P, Maynard, M, Radenne, S, Amiri, M, Valour, F, Augustin‐normand, C, Scholtes, C, Le‐thi, T.T, Chavanet, P, Duong van Huyen, M, Buisson, M, Waldner‐combernoux, A, Mahy, S, Salmon Rousseau, A, Martins, C, Galim, S, Lambert, D, Nguyen, Y, Berger, J.L, Hentzien, M, Brodard, V, Partisani, M, Batard, M.L, Cheneau, C, Priester, M, Bernard‐henry, C, de Mautort, E, Fischer, P, Gantner, P, Fafi‐kremer, S, Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut des sciences de la santé publique [Marseille] (ISSPAM), Team MORPH3EUS (INSERM U1219 - UB - ISPED), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), CIC Bordeaux, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, AP-HP - Hôpital Antoine Béclère [Clamart], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Bordeaux [Bordeaux], Hôpital Cochin [AP-HP], Université Paris Descartes - Paris 5 (UPD5), Physiopathologie du système immunitaire (Inserm U1223), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), ANRS CO13 HEPAVIH Study Group: F Roustant, P Platterier, I Kmiec, L Traore, S Lepuil, S Parlier, V Sicart-Payssan, E Bedel, S Anriamiandrisoa, C Pomes, M Mole, C Bolliot, P Catalan, M Mebarki, A Adda-Lievin, P Thilbaut, Y Ousidhoum, F Z Makhoukhi, O Braik, R Bayoud, C Gatey, M P Pietri, V Le Baut, R Ben Rayana, D Bornarel, C Chesnel, D Beniken, M Pauchard, S Akel, C Lions, A Ivanova, A-S Ritleg, C Debreux, L Chalal, J Zelie, H Hue, A Soria, M Cavellec, S Breau, A Joulie, P Fisher, S Gohier, D Croisier-Bertin, S Ogoudjobi, C Brochier, V Thoirain-Galvan, M Le Cam, M Chalouni, V Conte, L Dequae-Merchadou, M Desvallees, C Gilbert, S Gillet, R Knight, T Lemboub, L Michel, M Mora, C Protopopescu, P Roux, S Tezkratt, C Ramier, A Sow, M Bureau, P Trimoulet, J Izopet, L Serfaty, V Paradis, B Spire, Valantin, J Chas, O Zaegel-Faucher, K Barange, A Naqvi, E Rosenthal, A Bicart-See, O Bouchaud, A Gervais, C Lascoux-Combe, C Goujard, K Lacombe, C Duvivier, D Neau, P Morlat, F Bani-Sadr, L Meyer, F Boufassa, B Autran, A M Roque, C Solas, H Fontaine, D Costagliola, L Piroth, A Simon, D Zucman, F Boué, P Miailhes, E Billaud, H Aumaître, D Rey, G Peytavin, V Petrov-Sanchez, A Levier, R Usubillaga, B Terris, P Tremeaux, C Katlama, H Stitou, P Cacoub, S Nafissa, Y Benhamou, F Charlotte, S Fourati, I Poizot-Martin, O Zaegel, H Laroche, C Tamalet, P Callard, F Bendjaballah, C Amiel, C Le Pendeven, B Marchou, L Alric, S Metivier, J Selves, F Larroquette, V Rio, J Haudebourg, M C Saint-Paul, A De Monte, V Giordanengo, C Partouche, A Martin, M Ziol, Y Baazia, V Iwaka-Bande, A Gerber, M Uzan, D Garipuy, M J Ferro-Collados, J Selves, F Nicot, Y Yazdanpanah, H Adle-Biassette, G Alexandre, J M Molina, P Bertheau, M L Chaix, C Delaugerre, S Maylin, J Bottero, J Krause, P M Girard, D Wendum, P Cervera, J Adam, C Viala, D Vittecocq, Y Quertainmont, E Teicher, C Pallier, O Lortholary, C Rouzaud, J Lourenco, F Touam, C Louisin, V Avettand-Fenoel, E Gardiennet, A Mélard, A Ochoa, E Blanchard, S Castet-Lafarie, C Cazanave, D Malvy, M Dupon, H Dutronc, F Dauchy, L Lacaze-Buzy, A Desclaux, P Bioulac-Sage, S Reigadas, D Lacoste, F Bonnet, N Bernard, M Hessamfar, J F Paccalin, C Martell, M C Pertusa, M Vandenhende, P Mercié, D Malvy, T Pistone, M C Receveur, M Méchain, P Duffau, C Rivoisy, I Faure, S Caldato, P Bioulac-Sage, S Reigadas, P Bellecave, C Tumiotto, J L Pellegrin, J F Viallard, E Lazzaro, C Greib, P Bioulac-Sage, S Reigadas, C Majerholc, M Brollo, E Farfour, J Polo Devoto, I Kansau, V Chambrin, C Pignon, L Berroukeche, R Fior, V Martinez, M Favier, C Deback, Y Lévy, S Dominguez, J D Lelièvre, A S Lascaux, G Melica, F Raffi, C Allavena, V Reliquet, D Boutoille, C Biron, M Lefebvre, N Hall, S Bouchez, A Rodallec, L Le Guen, C Hemon, D Peyramond, C Chidiac, F Ader, F Biron, A Boibieux, L Cotte, T Ferry, T Perpoint, J Koffi, F Zoulim, F Bailly, P Lack, M Maynard, S Radenne, M Amiri, F Valour, J Koffi, F Zoulim, F Bailly, P Lack, M Maynard, S Radenne, C Augustin-Normand, C Scholtes, T T Le-Thi, P Chavanet, M Duong Van Huyen, M Buisson, A Waldner-Combernoux, S Mahy, A Salmon Rousseau, C Martins, S Galim, D Lambert, Y Nguyen, J L Berger, M Hentzien, V Brodard, M Partisani, M L Batard, C Cheneau, M Priester, C Bernard-Henry, E de Mautort, P Fischer, P Gantner, S Fafi-Kremer, Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris], Statistics In System biology and Translational Medicine (SISTM), Inria Bordeaux - Sud-Ouest, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)- Bordeaux population health (BPH), and Malbec, Odile
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0303 health sciences ,Hepatology ,business.industry ,[SDV]Life Sciences [q-bio] ,Human immunodeficiency virus (HIV) ,MEDLINE ,Physical activity ,medicine.disease_cause ,3. Good health ,[SDV] Life Sciences [q-bio] ,03 medical and health sciences ,0302 clinical medicine ,Infectious Diseases ,Virology ,Medicine ,030211 gastroenterology & hepatology ,business ,Eating behaviour ,ComputingMilieux_MISCELLANEOUS ,030304 developmental biology ,Clinical psychology - Abstract
International audience; No abstract available
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- 2021
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25. Nutrición de la mujer embarazada
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Ayoubi, J.-M., Hirt, R., Badiou, W., Hininger-Favier, I., Favier, M., Zraik-Ayoubi, F., Berrebi, A., and Pons, J.-C.
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- 2012
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26. Double-Blind Supplementation with Trace Elements, Magnesium and Vitamins during Pregnancy in a Randomly Selected Population
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Faure, H., Favier, M., Thauvin, E., Arnaud, J., Fusselier, M., Favier, A., Nève, Jean, editor, Chappuis, Philippe, editor, and Lamand, Michel, editor
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- 1996
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27. Modellierung und Simulation leitungsgebundener Landmaschinen
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Favier, M., primary, Auclaire, C., additional, Feick, S., additional, Fischer, T., additional, Hruszczak, M., additional, Michael, V., additional, Su, Y., additional, and Seewig, J., additional
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- 2016
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28. Loss of dopaminergic nigrostriatal neurons accounts for the motivational and affective deficits in Parkinson’s disease
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Drui, G, Carnicella, S, Carcenac, C, Favier, M, Bertrand, A, Boulet, S, and Savasta, M
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- 2014
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29. POSTER ABSTRACTS
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Stifani, BM, primary, Favier, M, additional, Horgan, TM, additional, Murphy, M, additional, Benfield, NC, additional, and Chavkin, W, additional
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- 2021
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30. Patient-reported symptoms during direct-acting antiviral treatment: A real-life study in HIV-HCV coinfected patients (ANRS CO13 HEPAVIH)
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Salmon, D., Wittkop, L., Sogni, P., Esterle, L., Trimoulet, P., Izopet, J., Serfaty, L., Paradis, V., Spire, B., Carrieri, P., Valantin, M.A., Pialoux, G., Chas, J., Poizot-Martin, I., Barange, K., Naqvi, A., Rosenthal, E., Bicart-See, A., Bouchaud, O., Gervais, A., Lascoux-Combe, C., Goujard, C., Lacombe, K., Duvivier, C., Neau, D., Morlat, P., Bani-Sadr, F., Meyer, L., Boufassa, F., Autran, B., Roque, A.M., Solas, C., Fontaine, H., Costagliola, D., Piroth, L., Simon, A., Zucman, D., Boué, F., Miailhes, P., Billaud, E., Aumaître, H., Rey, D., Peytavin, G., Petrov-Sanchez, V., Lebrasseur-Longuet, D., Usubillaga, R., Terris, B., Tremeaux, P., Katlama, C., Stitou, H., Cacoub, P., Nafissa, S., Benhamou, Y., Charlotte, F., Fourati, S., Zaegel, O., Laroche, H., Tamalet, C., Callard, P., Bendjaballah, F., Amiel, C., Le Pendeven, C., Marchou, B., Alric, L., Metivier, S., Selves, J., Larroquette, F., Rio, V., Haudebourg, J., Saint-Paul, M.C., De Monte, A., Giordanengo, V., Partouche, C., Martin, A., Ziol, M., Baazia, Y., Iwaka-Bande, V., Gerber, A., Uzan, M., Garipuy, D., Ferro-Collados, M.J., Nicot, F., Yazdanpanah, Y., Adle-Biassette, H., Alexandre, G., Molina, J.M., Bertheau, P., Chaix, M.L., Delaugerre, C., Maylin, S., Bottero, J., Krause, J., Girard, P.M., Wendum, D., Cervera, P., Adam, J., Viala, C., Vittecocq, D., Quertainmont, Y., Teicher, E., Pallier, C., Lortholary, O., Rouzaud, C., Lourenco, J., Touam, F., Louisin, C., Avettand-Fenoel, V., Gardiennet, E., Mélard, A., Ochoa, A., Blanchard, E., Castet-Lafarie, S., Cazanave, C., Malvy, D., Dupon, M., Dutronc, H., Dauchy, F., Lacaze-Buzy, L., Desclaux, A., Bioulac-Sage, P., Reigadas, S., Lacoste, D., Bonnet, F., Bernard, N., Hessamfar, J, M., Paccalin, F., Martell, C., Pertusa, M.C., Vandenhende, M., Mercié, P., Pistone, T., Receveur, M.C., Méchain, M., Duau, P., Rivoisy, C., Faure, I., Caldato, S., Bellecave, P., Tumiotto, C., Pellegrin, J.L., Viallard, J.F., Lazzaro, E., Greib, C., Majerholc, C., Brollo, M., Farfour, E., Polo Devoto, J., Kansau, I., Chambrin, V., Pignon, C., Berroukeche, L., Fior, R., Martinez, V., Abgrall, S., Favier, M., Deback, C., Lévy, Y., Dominguez, S., Lelièvre, J.D., Lascaux, A.S., Melica, G., Raffi, F., Allavena, C., Reliquet, V., Boutoille, D., Biron, C., Lefebvre, M., Hall, N., Bouchez, S., Rodallec, A., Le Guen, L., Hemon, C., Peyramond, D., Chidiac, C., Ader, F., Biron, F., Boibieux, A., Cotte, L., Ferry, T., Perpoint, T., Koffi, J., Zoulim, F., Bailly, F., Lack, P., Maynard, M., Radenne, S., Amiri, M., Valour, F., Augustin-Normand, C., Scholtes, C., Le-Thi, T.T., Chavanet, P., Duong Van Huyen, M., Buisson, M., Waldner-Combernoux, A., Mahy, S., Binois, R., Simonet-Lann, A.L., Croisier-Bertin, D., Salmon Rousseau, A., Martins, C., Galim, S., Lambert, D., Nguyen, Y., Berger, J.L., Hentzien, M., Brodard, V., Partisani, M., Batard, M.L., Cheneau, C., Priester, M., Bernard-Henry, C., de Mautort, E., Gantner et S Fafi-Kremer, P., Roustant, F., Platterier, P., Kmiec, I., Traore, L., Lepuil, S., Parlier, S., Sicart-Payssan, V., Bedel, E., Anriamiandrisoa, S., Pomes, C., Mole, M., Bolliot, C., Catalan, P., Mebarki, M., Adda-Lievin, A., Thilbaut, P., Ousidhoum, Y., Makhoukhi, F.Z., Braik, O., Bayoud, R., Gatey, C., Pietri, M.P., Le Baut, V., Ben Rayana, R., Bornarel, D., Chesnel, C., Beniken, D., Pauchard, M., Akel, S., Lions, C., Ivanova, A., Ritleg, A.-S., Debreux, C., Chalal, L., Zelie, J., Hue, H., Soria, A., Cavellec, M., Breau, S., Joulie, A., Fisher, P., Gohier, S., Ogoudjobi, S., Brochier, C., Thoirain-Galvan, V., Le Cam, M., Chalouni, M., Conte, V., Dequae-Merchadou, L., Desvallees, M., Gilbert, C., Gillet, S., Knight, R., Lemboub, T., Marcellin, F., Michel, L., Mora, M., Protopopescu, C., Roux, P., Tezkratt, S., Barré, T., Baudoin, M., Santos, M., Di Beo, V., Nishimwe, M., Marcellin, Fabienne, Di Beo, Vincent, Aumaitre, Hugues, Mora, Marion, Wittkop, Linda, Duvivier, Claudine, Protopopescu, Camelia, Lacombe, Karine, Esterle, Laure, Berenger, Cyril, Gilbert, Camille, Bouchaud, Olivier, Poizot-Martin, Isabelle, Sogni, Philippe, Salmon-Ceron, Dominique, and Carrieri, Patrizia
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- 2020
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31. Ramsey-comb precision spectroscopy in xenon at vacuum ultraviolet wavelengths produced with high-order harmonic generation
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Dreissen, L. S., Roth, C., Gründeman, E. L., Krauth, J. J., Favier, M. G. J., Eikema, K. S. E., Atoms, Molecules, Lasers, and LaserLaB - Physics of Light
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Physics ,Phase (waves) ,chemistry.chemical_element ,Laser ,7. Clean energy ,01 natural sciences ,010305 fluids & plasmas ,law.invention ,Wavelength ,Xenon ,chemistry ,law ,Extreme ultraviolet ,0103 physical sciences ,Harmonic ,High harmonic generation ,SDG 7 - Affordable and Clean Energy ,Atomic physics ,010306 general physics ,Spectroscopy - Abstract
The remarkable progress in the field of laser spectroscopy induced by the invention of the frequency-comb laser has enabled many high-precision tests of fundamental theory and searches for new physics. Extending frequency-comb-based spectroscopy techniques to the vacuum and extreme ultraviolet spectral range would enable frequency measurements of transitions in, e.g., heavier hydrogen-like systems and open up new possibilities for tests of quantum electrodynamics and measurements of fundamental constants. The two main approaches, full-repetition rate up-conversion in a resonator and two-pulse amplification and up-conversion for the Ramsey-comb technique, rely on high-order harmonic generation (HHG), which is known to induce spurious phase shifts from plasma formation. After our initial report [Phys. Rev. Lett. 123, 143001 (2019)PRLTAO0031-900710.1103/PhysRevLett.123.143001], in this article we give a detailed account of how the Ramsey-comb spectroscopy technique is used to probe the dynamics of this plasma with high precision and enables accurate spectroscopy in the vacuum ultraviolet. It is based on recording Ramsey fringes that track the phase evolution of a superposition state in xenon atoms excited by two up-converted frequency-comb laser pulses. In this manner, phase shifts up to 1 rad induced by the HHG process could be observed at nanosecond timescales with mrad-level accuracy at 110 nm. We also show that such phase shifts can be reduced to a negligible level of a few mrad. As a result, we were able to measure the 5p6→5p58s2[3/2]1 transition in Xe132 at 110 nm (the seventh harmonic of 770 nm) with sub-MHz accuracy, leading to a transition frequency of 2726086012471(630)kHz. This value is 104 times more precise than the previous determination and the fractional accuracy of 2.3×10-10 is 3.6 times better than the previous best spectroscopic measurement using high-order harmonic generation. Additionally, the isotope shifts between Xe132 and two other isotopes (Xe134 and Xe136) were determined with an accuracy of 420 kHz. The method can be readily extended to achieve kHz-level accuracy by increasing the pulse delay, e.g., to measure the 1S-2S transition in He+. Therefore, the Ramsey-comb method shows great promise for high-precision spectroscopy of targets requiring vacuum ultraviolet and extreme ultraviolet wavelengths.
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- 2020
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32. Effects of a combined micronutrient supplementation on maternal biological status and newborn anthropometrics measurements: a randomized double-blind, placebo-controlled trial in apparently healthy pregnant women
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Hininger, I, Favier, M, Arnaud, J, Faure, H, Thoulon, J M, Hariveau, E, Favier, A, and Roussel, A M
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- 2004
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33. Trace Element and Vitamin Deficiencies in French Pregnant Women
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Hininger, I., Favier, M., Faure, H., Arnaud, J., Khatir, F., Thoulon, J., Hariveau, E., Favier, A., Roussel, A. M., Roussel, A. M., editor, Anderson, R. A., editor, and Favier, A. E., editor
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- 2002
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34. Preparation and Laser Trapping of Cold Circular Rydberg Atoms for Quantum Simulation
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Méhaignerie, P., primary, Cortinas, R., additional, Favier, M., additional, Ravon, B., additional, Machu, Y., additional, Raimond, J.M., additional, Sayrin, C., additional, and Brune, M., additional
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- 2021
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35. Search for transient variations of the fine structure constant and dark matter using fiber-linked optical atomic clocks
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Roberts, B M, primary, Delva, P, additional, Al-Masoudi, A, additional, Amy-Klein, A, additional, Bærentsen, C, additional, Baynham, C F A, additional, Benkler, E, additional, Bilicki, S, additional, Bize, S, additional, Bowden, W, additional, Calvert, J, additional, Cambier, V, additional, Cantin, E, additional, Curtis, E A, additional, Dörscher, S, additional, Favier, M, additional, Frank, F, additional, Gill, P, additional, Godun, R M, additional, Grosche, G, additional, Guo, C, additional, Hees, A, additional, Hill, I R, additional, Hobson, R, additional, Huntemann, N, additional, Kronjäger, J, additional, Koke, S, additional, Kuhl, A, additional, Lange, R, additional, Legero, T, additional, Lipphardt, B, additional, Lisdat, C, additional, Lodewyck, J, additional, Lopez, O, additional, Margolis, H S, additional, Álvarez-Martínez, H, additional, Meynadier, F, additional, Ozimek, F, additional, Peik, E, additional, Pottie, P-E, additional, Quintin, N, additional, Sanner, C, additional, De Sarlo, L, additional, Schioppo, M, additional, Schwarz, R, additional, Silva, A, additional, Sterr, U, additional, Tamm, Chr, additional, Le Targat, R, additional, Tuckey, P, additional, Vallet, G, additional, Waterholter, T, additional, Xu, D, additional, and Wolf, P, additional
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- 2020
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36. Long-lived circular Rydberg states of laser-cooled rubidium atoms in a cryostat
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Cantat-Moltrecht, T., primary, Cortiñas, R., additional, Ravon, B., additional, Méhaignerie, P., additional, Haroche, S., additional, Raimond, J. M., additional, Favier, M., additional, Brune, M., additional, and Sayrin, C., additional
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- 2020
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37. Laser Trapping of Circular Rydberg Atoms
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Cortiñas, R. G., primary, Favier, M., additional, Ravon, B., additional, Méhaignerie, P., additional, Machu, Y., additional, Raimond, J. M., additional, Sayrin, C., additional, and Brune, M., additional
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- 2020
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38. Accurate laser frequency locking to optical frequency combs under low-signal-to-noise-ratio conditions
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Guo, C., primary, Favier, M., additional, Galland, N., additional, Cambier, V., additional, Álvarez-Martínez, H., additional, Lours, M., additional, De Sarlo, L., additional, Andia, M., additional, Le Targat, R., additional, and Bize, S., additional
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- 2020
- Full Text
- View/download PDF
39. Patient-reported symptoms during direct-acting antiviral treatment: A real-life study in HIV-HCV coinfected patients (ANRS CO13 HEPAVIH)
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Marcellin, Fabienne, primary, Di Beo, Vincent, additional, Aumaitre, Hugues, additional, Mora, Marion, additional, Wittkop, Linda, additional, Duvivier, Claudine, additional, Protopopescu, Camelia, additional, Lacombe, Karine, additional, Esterle, Laure, additional, Berenger, Cyril, additional, Gilbert, Camille, additional, Bouchaud, Olivier, additional, Poizot-Martin, Isabelle, additional, Sogni, Philippe, additional, Salmon-Ceron, Dominique, additional, Carrieri, Patrizia, additional, Salmon, D., additional, Wittkop, L., additional, Sogni, P., additional, Esterle, L., additional, Trimoulet, P., additional, Izopet, J., additional, Serfaty, L., additional, Paradis, V., additional, Spire, B., additional, Carrieri, P., additional, Valantin, M.A., additional, Pialoux, G., additional, Chas, J., additional, Poizot-Martin, I., additional, Barange, K., additional, Naqvi, A., additional, Rosenthal, E., additional, Bicart-See, A., additional, Bouchaud, O., additional, Gervais, A., additional, Lascoux-Combe, C., additional, Goujard, C., additional, Lacombe, K., additional, Duvivier, C., additional, Neau, D., additional, Morlat, P., additional, Bani-Sadr, F., additional, Meyer, L., additional, Boufassa, F., additional, Autran, B., additional, Roque, A.M., additional, Solas, C., additional, Fontaine, H., additional, Costagliola, D., additional, Piroth, L., additional, Simon, A., additional, Zucman, D., additional, Boué, F., additional, Miailhes, P., additional, Billaud, E., additional, Aumaître, H., additional, Rey, D., additional, Peytavin, G., additional, Petrov-Sanchez, V., additional, Lebrasseur-Longuet, D., additional, Usubillaga, R., additional, Terris, B., additional, Tremeaux, P., additional, Katlama, C., additional, Stitou, H., additional, Cacoub, P., additional, Nafissa, S., additional, Benhamou, Y., additional, Charlotte, F., additional, Fourati, S., additional, Zaegel, O., additional, Laroche, H., additional, Tamalet, C., additional, Callard, P., additional, Bendjaballah, F., additional, Amiel, C., additional, Le Pendeven, C., additional, Marchou, B., additional, Alric, L., additional, Metivier, S., additional, Selves, J., additional, Larroquette, F., additional, Rio, V., additional, Haudebourg, J., additional, Saint-Paul, M.C., additional, De Monte, A., additional, Giordanengo, V., additional, Partouche, C., additional, Martin, A., additional, Ziol, M., additional, Baazia, Y., additional, Iwaka-Bande, V., additional, Gerber, A., additional, Uzan, M., additional, Garipuy, D., additional, Ferro-Collados, M.J., additional, Nicot, F., additional, Yazdanpanah, Y., additional, Adle-Biassette, H., additional, Alexandre, G., additional, Molina, J.M., additional, Bertheau, P., additional, Chaix, M.L., additional, Delaugerre, C., additional, Maylin, S., additional, Bottero, J., additional, Krause, J., additional, Girard, P.M., additional, Wendum, D., additional, Cervera, P., additional, Adam, J., additional, Viala, C., additional, Vittecocq, D., additional, Quertainmont, Y., additional, Teicher, E., additional, Pallier, C., additional, Lortholary, O., additional, Rouzaud, C., additional, Lourenco, J., additional, Touam, F., additional, Louisin, C., additional, Avettand-Fenoel, V., additional, Gardiennet, E., additional, Mélard, A., additional, Ochoa, A., additional, Blanchard, E., additional, Castet-Lafarie, S., additional, Cazanave, C., additional, Malvy, D., additional, Dupon, M., additional, Dutronc, H., additional, Dauchy, F., additional, Lacaze-Buzy, L., additional, Desclaux, A., additional, Bioulac-Sage, P., additional, Reigadas, S., additional, Lacoste, D., additional, Bonnet, F., additional, Bernard, N., additional, Hessamfar, J, M., additional, Paccalin, F., additional, Martell, C., additional, Pertusa, M.C., additional, Vandenhende, M., additional, Mercié, P., additional, Pistone, T., additional, Receveur, M.C., additional, Méchain, M., additional, Duau, P., additional, Rivoisy, C., additional, Faure, I., additional, Caldato, S., additional, Bellecave, P., additional, Tumiotto, C., additional, Pellegrin, J.L., additional, Viallard, J.F., additional, Lazzaro, E., additional, Greib, C., additional, Majerholc, C., additional, Brollo, M., additional, Farfour, E., additional, Polo Devoto, J., additional, Kansau, I., additional, Chambrin, V., additional, Pignon, C., additional, Berroukeche, L., additional, Fior, R., additional, Martinez, V., additional, Abgrall, S., additional, Favier, M., additional, Deback, C., additional, Lévy, Y., additional, Dominguez, S., additional, Lelièvre, J.D., additional, Lascaux, A.S., additional, Melica, G., additional, Raffi, F., additional, Allavena, C., additional, Reliquet, V., additional, Boutoille, D., additional, Biron, C., additional, Lefebvre, M., additional, Hall, N., additional, Bouchez, S., additional, Rodallec, A., additional, Le Guen, L., additional, Hemon, C., additional, Peyramond, D., additional, Chidiac, C., additional, Ader, F., additional, Biron, F., additional, Boibieux, A., additional, Cotte, L., additional, Ferry, T., additional, Perpoint, T., additional, Koffi, J., additional, Zoulim, F., additional, Bailly, F., additional, Lack, P., additional, Maynard, M., additional, Radenne, S., additional, Amiri, M., additional, Valour, F., additional, Augustin-Normand, C., additional, Scholtes, C., additional, Le-Thi, T.T., additional, Chavanet, P., additional, Duong Van Huyen, M., additional, Buisson, M., additional, Waldner-Combernoux, A., additional, Mahy, S., additional, Binois, R., additional, Simonet-Lann, A.L., additional, Croisier-Bertin, D., additional, Salmon Rousseau, A., additional, Martins, C., additional, Galim, S., additional, Lambert, D., additional, Nguyen, Y., additional, Berger, J.L., additional, Hentzien, M., additional, Brodard, V., additional, Partisani, M., additional, Batard, M.L., additional, Cheneau, C., additional, Priester, M., additional, Bernard-Henry, C., additional, de Mautort, E., additional, Gantner et S Fafi-Kremer, P., additional, Roustant, F., additional, Platterier, P., additional, Kmiec, I., additional, Traore, L., additional, Lepuil, S., additional, Parlier, S., additional, Sicart-Payssan, V., additional, Bedel, E., additional, Anriamiandrisoa, S., additional, Pomes, C., additional, Mole, M., additional, Bolliot, C., additional, Catalan, P., additional, Mebarki, M., additional, Adda-Lievin, A., additional, Thilbaut, P., additional, Ousidhoum, Y., additional, Makhoukhi, F.Z., additional, Braik, O., additional, Bayoud, R., additional, Gatey, C., additional, Pietri, M.P., additional, Le Baut, V., additional, Ben Rayana, R., additional, Bornarel, D., additional, Chesnel, C., additional, Beniken, D., additional, Pauchard, M., additional, Akel, S., additional, Lions, C., additional, Ivanova, A., additional, Ritleg, A.-S., additional, Debreux, C., additional, Chalal, L., additional, Zelie, J., additional, Hue, H., additional, Soria, A., additional, Cavellec, M., additional, Breau, S., additional, Joulie, A., additional, Fisher, P., additional, Gohier, S., additional, Ogoudjobi, S., additional, Brochier, C., additional, Thoirain-Galvan, V., additional, Le Cam, M., additional, Chalouni, M., additional, Conte, V., additional, Dequae-Merchadou, L., additional, Desvallees, M., additional, Gilbert, C., additional, Gillet, S., additional, Knight, R., additional, Lemboub, T., additional, Marcellin, F., additional, Michel, L., additional, Mora, M., additional, Protopopescu, C., additional, Roux, P., additional, Tezkratt, S., additional, Barré, T., additional, Baudoin, M., additional, Santos, M., additional, Di Beo, V., additional, and Nishimwe, M., additional
- Published
- 2020
- Full Text
- View/download PDF
40. Zinc et grossesse
- Author
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Favier, M. and Hininger-Favier, I.
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- 2005
- Full Text
- View/download PDF
41. High resolution LC tandem for MS for the identification of unknown polar oxidation products of pyralozone pharmaceuticals, their metabolites and biotransformation products : Hoge-resolutie LS tandem MS voor de identificatie van onbekende polaire oxidatieproducten van pyralozone geneesmiddelen, hun metaboliten en biotransformatie producten
- Author
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Favier, M, Van Schepdael, A, and Cabooter, D
- Abstract
In this thesis, the issue of the contamination of the aquatic environment by pyrazolone type pharmaceuticals and metabolites and two oxidative processes of remediation was studied. Several pyrazolone type compounds were studied. Dipyrone - also named metamizole - is one of the most widely used analgesic pharmaceuticals. Completely metabolized in the human body, it produces 4-acetamidoantipyrine (AAA) and 4-formylaminoantipyrine (FAA) that can be found in water streams in levels in the ng/L to μg/L range. Next to those, phenazone and propyphenazone, also analgesics, were selected to bring the total of studied compounds to four. An analytical method for the determination of these four compounds was developed and validated. It was applied on environmental water samples from Germany and Brazil, where dipyrone is available on prescription and over the counter, respectively. The difference in concentration measured showed an impact of the over the counter availability, although this difference was not considered to be large. The samples from Brazil demonstrated that the contamination of the aquatic environment by these molecules is large with levels of AAA exiting WWTP in the μg/L range and further detection in surface waters, water reservoirs and drinking water. Closed-loop bottle tests were used to mimic microbial degradation and study the formed by-products. Degradation of AAA was only observed when AAA was solely present in the solution. As soon as another carbon source was available, the level of AAA remained stable. Our study unveiled four degradation products being formed, the major one being 4-aminoantipyrine (AA) by a deacetylation mechanism. The other observed degradation mechanism was a combination of oxidation of a C=C double-bond and denitrification. A grab sample study at a wastewater plant revealed levels of all degradation products at different stages of the wastewater process. Contrary to AAA, FAA has been shown in literature, to be resilient to biological treatment. Additionally, phenazone, propyphenazone, AAA and FAA were treated with ozone under laboratory conditions and 17 degradation products were identified by an elucidation approach based on high-resolution mass spectrometry (LTQ Orbitrap). Typical oxidation of carbon-carbon double bonds by ozone was observed among other mechanisms of ring opening. It was demonstrated that the reactivity of these compounds with ozone is high (rate constants kO3 ranging from 6.5×104 to 2.4×106 M-1s-1). The degradation of phenazone, propyphenazone, acetamido antipyrine and formyl aminoantipyrine by UV radiation was investigated as well under laboratory conditions. An elucidation approach based on high-resolution mass spectrometry resulted in the identification of 11 degradation products. A mechanism of ring opening via the oxidation of the N-N bond of the pyrazolone ring was observed as well as the more typical oxidation of carbon-carbon double bonds. Aside from the degradation products, the capacity of formyl aminoantipyrine to produce trimers and dimers was demonstrated. The dimers were shown to be persistent despite continuous UV radiation. The toxicity of the formed degradation products was estimated by quantitative structure-activity relationships (QSAR). It was shown that, when the carbon-carbon double bond is partially oxidized to an epoxy, the toxicity towards fish and daphnids is higher than that of the parent compound. By further oxidizing the molecules, a common degradation product - 1-acetyl-1-methyl-2-phenylhydrazide (AMPH) - was also found to be more toxic than its parent compounds, which is of concern since this compound has previously been reported in environmental waters. Overall, this class of compounds is present in high levels in wastewater and is prone to transformation during the oxidative processes used as tertiary treatment steps. It is considered that removal should not only be assessed for the parent compounds but also for their degradation products. The task at hand is still large on this side given the number of different possible pharmaceutical compounds present in WWTP effluents. However, improvements in analytical techniques, as well as their combination with in-silico methods, could provide the knowledge needed to optimize oxidative treatment processes. status: published
- Published
- 2019
42. Faut-il supplémenter en fer les femmes enceintes ?
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Favier, M and Hininger-Favier, I
- Published
- 2004
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43. L’atlas transcriptome single-cell des cancers de la surrénale identifie des « écotypes » tumoraux associés à la survie
- Author
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Jouinot, A., Martin, Y., Foulonneau, T., Bendjelal, Y., Violon, F., Calvet, P., Izac, B., Letourneur, F., Bertholle, C., Andrieu, M., Onifarasoaniaina, R., Favier, M., De Guitaut, C., Fraikin, A., De Murat, D., Armignacco, R., Benanteur, N., Sibony, M., Perlemoine, K., Vaduva, P., Bouys, L., Bonnet Serrano, F., Dousset, B., Gaillard, M., Pasmant, E., Barat, M., Dohan, A., Haissaguerre, M., Tabarin, A., Libe, R., Guignat, L., Groussin, L., Berthon, A., Ragazzon, B., Bertherat, J., and Assie, G.
- Abstract
La classification transcriptome sépare les tumeurs bénignes (cluster « C2 ») des corticosurrénalomes et identifie deux groupes de corticosurrénalomes, « C1A » (signature stéroïde et prolifération), de mauvais pronostic, et « C1B » (signature immune), de pronostic bien meilleur. Ces signatures étant définies à l’échelle du tissu (« bulk »), la composition et le rôle du microenvironnement tumoral restent peu connus. L’objectif de cette étude est de réaliser l’atlas cellulaire des corticosurrénalomes.
- Published
- 2024
- Full Text
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44. High-Precision Ramsey-Comb Spectroscopy Based on High-Harmonic Generation
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Dreissen, L. S., primary, Roth, C., additional, Gründeman, E. L., additional, Krauth, J. J., additional, Favier, M., additional, and Eikema, K. S. E., additional
- Published
- 2019
- Full Text
- View/download PDF
45. First Demonstration of VUV Ramsey-Comb Excitation Based on HHG; Towards 1S-2S He+ Excitation
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Grundeman, E. L., primary, Dreissen, L. S., additional, Roth, C., additional, Krauth, J. J., additional, Favier, M., additional, and Eikema, K. S. E., additional
- Published
- 2019
- Full Text
- View/download PDF
46. POSTER ABSTRACTS: P19 A NEW ABORTION SERVICE IN THE MIDST OF A PANDEMIC: GENERAL PRACTITIONERS’ PERSPECTIVES ON COVID-19 AND COMMUNITY-BASED PROVISION OF EARLY MEDICAL ABORTION IN IRELAND
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Stifani, BM, Favier, M, Horgan, TM, Murphy, M, Benfield, NC, and Chavkin, W
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- 2021
- Full Text
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47. Impact à un an d’un dépistage élargi des infections sexuellement transmissibles (IST) au sein d’un centre gratuit d’information, de dépistage et de diagnostic (CeGIDD) des infections par le VIH, les hépatites virales et les IST de banlieue parisienne
- Author
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Gatey, C., primary, Bourgeois-Nicolaos, N., additional, Rouard, C., additional, Pallier, C., additional, Richard, C., additional, Favier, M., additional, Abgrall, S., additional, Boue, F., additional, and Kansau, I., additional
- Published
- 2018
- Full Text
- View/download PDF
48. The role of the glucose-sensing transcription factor carbohydrate-responsive element-binding protein pathway in termite queen fertility [plus Correction]
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Sillam-Dussès, David, Hanus, R., Poulsen, M., Roy, V., Favier, M., and Vasseur-Cognet, M.
- Published
- 2016
49. Single-beam interference from plain Gaussian and OAM wavefronts
- Author
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Popov, S., Favier, M., Popov, S., and Favier, M.
- Abstract
We implement an SLM to generate laser beams of variable orbital angular momentum, also referred as Laguerre- Gaussian beams. Input beam polarization takes into account a local birefringence of each pixel of the SLM. We identify the beam polarization eigenstates allowing generate L-G beams of different order via matching variable birefringence of every separate pixels. Zero-order beam passing through the SLM can interact with a generated OAM beam to create an interference pattern. Experimental results demonstrate good agreement with simulations., QC 20240110
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- 2016
- Full Text
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50. Genetic and Physiological Characterisation of Oenococcus oeni Strains to Perform Malolactic Fermentation in Wines
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Renouf, V., primary and Favier, M., additional
- Published
- 2016
- Full Text
- View/download PDF
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