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147 results on '"Fauth-Bühler, Mira"'

1. Substance Use Initiation, Particularly Alcohol, in Drug-Naive Adolescents: Possible Predictors and Consequences From a Large Cohort Naturalistic Study

Author

Rapp, Michael, Artiges, Eric, Schneider, Sophia, Paus, Tomas, Barbot, Alexis, Barker, Gareth, Bokde, Arun, Vetter, Nora, Büchel, Christian, Cattrell, Anna, Constant, Patrick, Gowland, Penny, Crombag, Hans, Dalley, Jeffrey, Decideur, Benjamin, Spranger, Tade, Ripley, Tamzin, Heym, Nadja, Flor, Herta, Sommer, Wolfgang, Fuchs, Birgit, Gallinat, Jürgen, Garavan, Hugh, Spanagel, Rainer, Kaviani, Mehri, Heinrichs, Bert, Andreas Heinz, Subramaniam, Naresh, Jia, Tianye, Ihlenfeld, Albrecht, Ireland, James, Ittermann, Bernd, Conrod, Patricia, Banaschewski, Tobias, Jones, Jennifer, Klaassen, Arno, Lalanne, Christophe, Lanzerath, Dirk, Lawrence, Claire, Lemaitre, Hervé, Desrivieres, Sylvane, Mallik, Catherine, Mann, Karl, Mar, Adam, Martinez-Medina, Lourdes, Martinot, Jean-Luc, Mennigen, Eva, Mesquita de Carvahlo, Fabiana, Schwartz, Yannick, Bruehl, Ruediger, Müller, Kathrin, Nees, Frauke, Nymberg, Charlotte, Lathrop, Mark, Robbins, Trevor, Pausova, Zdenka, Pentilla, Jani, Biondo, Francesca, Poline, Jean-Baptiste, Poustka, Luise, Millenet, Sabina, Smolka, Michael, Fröhner, Juliane, Struve, Maren, Williams, Steve, Hübner, Thomas, Bromberg, Uli, Aydin, Semiha, Rogers, John, Romanowski, Alexander, Schmäl, Christine, Schmidt, Dirk, Ripke, Stephan, Arroyo, Mercedes, Schubert, Florian, Pena-Oliver, Yolanda, Fauth-Bühler, Mira, Mignon, Xavier, Whelan, Robert, Speiser, Claudia, Fadai, Tahmine, Stephens, Dai, Ströhle, Andreas, Paillere, Marie-Laure, Strache, Nicole, Theobald, David, Jurk, Sarah, Vulser, Helene, Miranda, Ruben, Yacubilin, Juliana, Frouin, Vincent, Genauck, Alexander, Parchetka, Caroline, Gemmeke, Isabel, Kruschwitz, Johann, WeiB, Katharina, Walter, Henrik, Feng, Jianfeng, Papadopoulos, Dimitri, Filippi, Irina, Ing, Alex, Ruggeri, Barbara, Xu, Bing, Macare, Christine, Chu, Congying, Hanratty, Eanna, Burke Quinlan, Erin, Robert, Gabriel, Schumann, Gunter, Yu, Tao, Ziesch, Veronika, Stedman, Alicia, Ivanov, Iliyan, Parvaz, Muhammad A., Velthorst, Eva, Shaik, Riaz B., Sandin, Sven, Gan, Gabriela, Spechler, Philip, Albaugh, Matthew D., Chaarani, Bader, Mackey, Scott, Bokde, Arun L.W., Quinlan, Erin Burke, Desrivières, Sylvane, Grigis, Antoine, Heinz, Andreas, Paillère Martinot, Marie-Laure, Lemaitre, Herve, Orfanos, Dimitri Papadopoulos, Paus, Tomáš, Hohmann, Sarah, Fröhner, Juliane H., and Smolka, Michael N.

Published
2021
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2. Neural Correlates of Adolescent Irritability and Its Comorbidity With Psychiatric Disorders

Author

Rapp, Dr. Michael, Artiges, Dr. Eric, Schneider, Sophia, Bach, Christine, Paus, Dr. Tomas, Barbot, Alexis, Barker, Dr. Gareth, Bokde, Dr. Arun, Vetter, Dr. Nora, Büchel, Dr. Christian, Cattrell, Dr. Anna, Constant, Patrick, Gowland, Penny, Crombag, Dr. Hans, Czech, Katharina, Dalley, Dr. Jeffrey, Decideur, Benjamin, Spranger, Tade, Ripley, Dr. Tamzin, Heym, Dr. Nadja, Flor, Herta, Sommer, Dr. Wolfgang, Fuchs, Birgit, Gallinat, Dr. Jürgen, Garavan, Dr. Hugh, Spanagel, Dr. Rainer, Kaviani, Mehri, Heinrichs, Dr. Bert, Heinz, Dr. Andreas, Subramaniam, Naresh, Jia, Dr. Tianye, Ihlenfeld, Albrecht, Ireland, James, Ittermann, Dr. Bernd, Conrod, Dr. Patricia, Banaschewski, Dr. Tobias, Jones, Jennifer, Klaassen, Dr. Arno, Lalanne, Christophe, Lanzerath, Dr. Dirk, Lawrence, Dr. Claire, Lemaitre, Dr. Hervé, Desrivieres, Dr. Sylvane, Mallik, Catherine, Mann, Dr. Karl, Mar, Dr. Adam, Martinez-Medina, Lourdes, Martinot, Dr. Jean-Luc, Mennigen, Eva, Mesquita de Carvahlo, Dr. Fabiana, Schwartz, Yannick, Bruehl, Dr. Ruediger, Müller, Kathrin, Nees, Frauke, Nymberg, Charlotte, Lathrop, Dr. Mark, Robbins, Dr. Trevor, Pausova, Dr. Zdenka, Pentilla, Dr. Jani, Biondo, Dr. Francesca, Poline, Dr. Jean-Baptiste, Poustka, Dr. Luise, Millenet, Sabina, Smolka, Dr. Michael, Fröhner, Juliane, Struve, Dr. Maren, Williams, Dr. Steve, Hübner, Dr. Thomas, Bromberg, Uli, Aydin, Semiha, Rogers, John, Romanowski, Alexander, Schmäl, Dr. Christine, Schmidt, Dirk, Ripke, Stephan, Arroyo, Dr. Mercedes, Schubert, Dr. Florian, Pena-Oliver, Dr. Yolanda, Fauth-Bühler, Mira, Mignon, Xavier, Whelan, Dr. Robert, Speiser, Dr. Claudia, Fadai, Tahmine, Stephens, Dr. Dai, Ströhle, Dr. Andreas, Paillere, Dr. Marie-Laure, Strache, Nicole, Theobald, David, Jurk, Sarah, Vulser, Dr. Helene, Miranda, Ruben, Yacubilin, Dr. Juliana, Frouin, Vincent, Genauck, Alexander, Parchetka, Caroline, Gemmeke, Isabel, Kruschwitz, Johann, Weiss, Katharina, Walter, Dr. Henrik, Feng, Jianfeng, Papadopoulos, Dimitri, Filippi, Irina, Ing, Alex, Ruggeri, Dr. Barbara, Xu, Bing, Macare, Christine, Chu, Dr. Congying, Hanratty, Eanna, Burke Quinlan, Dr. Erin, Robert, Dr. Gabriel, Schumann, Dr. Gunter, Yu, Dr. Tao, Ziesch, Veronika, Stedman, Alicia, Chaarani, Bader, Kan, Kees-Jan, Mackey, Scott, Spechler, Philip A., Potter, Alexandra, Banaschewski, Tobias, Bokde, Arun L.W., Büchel, Christian, Cattrell, Anna, Conrod, Patricia J., Desrivières, Sylvane, Gallinat, Jürgen, Heinz, Andreas, Ittermann, Bernd, Martinot, Jean-Luc, Paus, Tomáš, Poustka, Luise, Smolka, Michael N., Walter, Henrik, Whelan, Robert, Stringaris, Argyris, Higgins, Stephen T., Schumann, Gunter, Garavan, Hugh, and Althoff, Robert R.

Published
2020
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3. Das Smartphone als ständiger Begleiter: Die Rolle von Maximierungstendenz und Belohnungsaufschub.

Author

Kohler, Sebastian A. and Fauth-Bühler, Mira

Subjects
*DELAY of gratification, *PERSONALITY, *FREEWARE (Computer software), *SMARTPHONES, *SOCIAL media, *SOCIAL impact
Abstract

Abstract: Aims: Smartphones are an integral part of our lives. Therefore, it is essential to identify risk factors for problematic usage. This study explores the relationship between two personality traits, namely the ability to delay gratification and the tendency to maximize, and problematic smartphone usage (PSN). The actual smartphone usage behavior, including social media usage, is considered. Method: Participants answered the scale assessing individual maximization tendency, the German translation of the Delaying Gratification Inventory, and the Smartphone Addiction Scale. Data from a total of 370 individuals were included in the analysis. A subsample of 128 participants additionally provided smartphone usage data over seven days. Statistical analyses were conducted using the free software jamovi. Results: In the overall sample, it is evident that the ability to delay gratification (β = –.33) and individual tendency to maximize (β =.45) each serve as predictors for PSN. Usage data from the subsample indicate that both the ability to delay gratification (β = –.24) and the tendency to maximize (β =.21) have a significant impact on the proportion of social media usage but not on the overall duration of smartphone usage. Conclusions: These findings provide starting points for measures to promote healthy smartphone usage. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Cannabis-Associated Psychotic-like Experiences Are Mediated by Developmental Changes in the Parahippocampal Gyrus

Author

Rapp, Michael, Artiges, Eric, Schneider, Sophia, Bach, Christine, Paus, Tomas, Barbot, Alexis, Barker, Gareth, Bokde, Arun, Vetter, Nora, Büchel, Christian, Cattrell, Anna, Constant, Patrick, Gowland, Penny, Crombag, Hans, Czech, Katharina, Dalley, Jeffrey, Decideur, Benjamin, Spranger, Tade, Ripley, Tamzin, Heym, Nadja, Flor, Herta, Sommer, Wolfgang, Fuchs, Birgit, Gallinat, Jürgen, Garavan, Hugh, Spanagel, Rainer, Kaviani, Mehri, Heinrichs, Bert, Heinz, Andreas, Subramaniam, Naresh, Jia, Tianye, Ihlenfeld, Albrecht, Delosis, James Ireland, Ittermann, Bernd, Conrod, Patricia, Banaschewski, Tobias, Jones, Jennifer, Klaassen, Arno, Lalanne, Christophe, Lanzerath, Dirk, Lawrence, Claire, Lemaitre, Hervé, Desrivieres, Sylvane, Mallik, Catherine, Mann, Karl, Mar, Adam, Martinez-Medina, Lourdes, Martinot, Jean-Luc, Mennigen, Eva, de Carvahlo, Fabiana Mesquita, Schwartz, Yannick, Bruehl, Ruediger, Müller, Kathrin, Nees, Frauke, Nymberg, Charlotte, Lathrop, Mark, Robbins, Trevor, Pausova, Zdenka, Pentilla, Jani, Biondo, Francesca, Poline, Jean-Baptiste, Hohmann, Sarah, Poustka, Luise, Millenet, Sabina, Smolka, Michael, Fröhner, Juliane, Struve, Maren, Williams, Steve, Hübner, Thomas, Bromberg, Uli, Aydin, Semiha, Rogers, John, Romanowski, Alexander, Schmäl, Christine, Schmidt, Dirk, Ripke, Stephan, Arroyo, Mercedes, Schubert, Florian, Pena-Oliver, Yolanda, Fauth-Bühler, Mira, Mignon, Xavier, Whelan, Robert, Speiser, Claudia, Fadai, Tahmine, Stephens, Dai, Ströhle, Andreas, Paillere, Marie-Laure, Strache, Nicole, Theobald, David, Jurk, Sarah, Vulser, Helene, Miranda, Ruben, Yacubilin, Juliana, Frouin, Vincent, Genauck, Alexander, Parchetka, Caroline, Gemmeke, Isabel, Kruschwitz, Johann, WeiB, Katharina, Walter, Henrik, Feng, Jianfeng, Papadopoulos, Dimitri, Filippi, Irina, Ing, Alex, Ruggeri, Barbara, Xu, Bing, Macare, Christine, Chu, Congying, Hanratty, Eanna, Quinlan, Erin Burke, Robert, Gabriel, Schumann, Gunter, Yu, Tao, Ziesch, Veronika, Stedman, Alicia, Zhu, Liping, Desrivières, Sylvane, Bi, Yan, Bokde, Arun L.W., Liu, ChuanXin, Ji, Lei, Ren, Decheng, Du, Li, Hou, Binyin, Paillère Martinot, Marie-Laure, Orfanos, Dimitri Papadopoulos, Luo, Qiang, Smolka, Michael N., Vetter, Nora C., Lei, Cai, Fröhner, Juliane H., He, Guang, and He, Lin

Published
2020
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7. Low Smoking Exposure, the Adolescent Brain, and the Modulating Role of CHRNA5 Polymorphisms

Author

Mann, Karl, Struve, Maren, Rietschel, Marcella, Spanagel, Rainer, Fauth-Bühler, Mira, Millenet, Sabina, Grimmer, Yvonne, Ivanov, Nikolay, Strache, Nicole, Rapp, Michael, Ströhle, Andreas, Reuter, Jan, Barbot, Alexis, Thyreau, Benjamin, Schwartz, Yannick, Lalanne, Christophe, Bricaud, Zuleima, Briand, Fanny Gollier, Lemaitre, Hervé, Massicotte, Jessica, Vulser, Helene, Pentillä, Jani, Galinowski, André, Jia, Tianye, Werts, Helen, Topper, Lauren, Reed, Laurence, Andrew, Chris, Mallik, Catherine, Ruggeri, Barbara, Nymberg, Charlotte, Smith, Lindsay, Loth, Eva, Havatzias, Stephanie, Stueber, Kerstin, Stringaris, Argyris, Constant, Patrick, Brühl, Ruediger, Ihlenfeld, Albrecht, Walaszek, Bernadeta, Hübner, Thomas, Müller, Kathrin, Ripke, Stephan, Rodehacke, Sarah, Mennigen, Eva, Schmidt, Dirk, Vetter, Nora, Ziesch, Veronika, Jones, Jennifer, Poline, Jean-Baptiste, Fadai, Tahmine, Yacubian, Juliana, Schneider, Sophia, Lawrence, Claire, Newman, Craig, Head, Kay, Heym, Nadja, Pausova, Zdenka, Tahmasebi, Amir, Chaarani, Bader, Kan, Kees-Jan, Mackey, Scott, Spechler, Philip A., Potter, Alexandra, Orr, Catherine, D’Alberto, Nicholas, Hudson, Kelsey E., Banaschewski, Tobias, Bokde, Arun L.W., Bromberg, Uli, Büchel, Christian, Cattrell, Anna, Conrod, Patricia J., Desrivières, Sylvane, Flor, Herta, Frouin, Vincent, Gallinat, Jürgen, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Martinot, Jean-Luc, Nees, Frauke, Papadopoulos-Orfanos, Dimitri, Paus, Tomáš, Poustka, Luise, Smolka, Michael N., Walter, Henrik, Whelan, Robert, Higgins, Stephen T., Schumann, Gunter, Althoff, Robert R., Stein, Elliot A., and Garavan, Hugh

Published
2019
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8. Neural Correlates of Failed Inhibitory Control as an Early Marker of Disordered Eating in Adolescents

Author

Rapp, Michael, Artiges, Eric, Schneider, Sophia, Bach, Christine, Paus, Tomas, Barbot, Alexis, Gareth Barker, Bokde, Arun, Vetter, Nora, Büchel, Christian, Cattrell, Anna, Constant, Patrick, Gowland, Penny, Crombag, Hans, Czech, Katharina, Dalley, Jeffrey, Decideur, Benjamin, Spranger, Tade, Ripley, Tamzin, Heym, Nadja, Flor, Herta, Sommer, Wolfgang, Fuchs, Birgit, Gallinat, Jürgen, Spanagel, Rainer, Kaviani, Mehri, Heinrichs, Bert, Andreas Heinz, Subramaniam, Naresh, Jia, Tianye, Ihlenfeld, Albrecht, Ireland, James, Ittermann, Bernd, Conrod, Patricia, Banaschewski, Tobias, Jones, Jennifer, Klaassen, Arno, Lalanne, Christophe, Lanzerath, Dirk, Lawrence, Claire, Lemaitre, Hervé, Desrivieres, Sylvane, Mallik, Catherine, Karl Mann, Mar, Adam, Martinez-Medina, Lourdes, Jean-Luc Martinot, Mennigen, Eva, Mesquita de Carvahlo, Fabiana, Schwartz, Yannick, Bruehl, Ruediger, Müller, Kathrin, Nees, Frauke, Nymberg, Charlotte, Lathrop, Mark, Trevor Robbins, Pausova, Zdenka, Jani Pentilla, Biondo, Francesca, Jean-Baptiste Poline, Hohmann, Sarah, Poustka, Luise, Millenet, Sabina, Michael Smolka, Fröhner, Juliane, Struve, Maren, Steve Williams, Hübner, Thomas, Bromberg, Uli, Aydin, Semiha, Rogers, John, Romanowski, Alexander, Schmäl, Christine, Schmidt, Dirk, Ripke, Stephan, Arroyo, Mercedes, Schubert, Florian, Pena-Oliver, Yolanda, Fauth-Bühler, Mira, Mignon, Xavier, Whelan, Robert, Speiser, Claudia, Fadai, Tahmine, Dai Stephens, Ströhle, Andreas, Paillere, Marie-Laure, Strache, Nicole, Theobald, David, Jurk, Sarah, Vulser, Helene, Miranda, Ruben, Yacubian, Juliana, Frouin, Vincent, Genauck, Alexander, Parchetka, Caroline, Gemmeke, Isabel, Kruschwitz, Johann, Weiß, Katharina, Walter, Henrik, Feng, Jianfeng, Papadopoulos, Dimitri, Filippi, Irina, Ing, Alex, Ruggeri, Barbara, Xu, Bing, Macare, Christine, Chu, Congying, Hanratty, Eanna, Burke Quinlan, Erin, Robert, Gabriel, Schumann, Gunter, Yu, Tao, Ziesch, Veronika, Stedman, Alicia, Bartholdy, Savani, O’Daly, Owen G., Campbell, Iain C., Barker, Gareth, Bokde, Arun L.W., Quinlan, Erin Burke, Desrivières, Sylvane, Garavan, Hugh, Heinz, Andreas, Martinot, Jean-Luc, Paillère Martinot, Marie-Laure, Orfanos, Dimitri Papadopoulos, Fröhner, Juliane H., Smolka, Michael N., and Schmidt, Ulrike

Published
2019
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11. Prediction of alcohol drinking in adolescents: Personality-traits, behavior, brain responses, and genetic variations in the context of reward sensitivity

Author

Heinrich, Angela, Müller, Kathrin U., Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L.W., Bromberg, Uli, Büchel, Christian, Conrod, Patricia, Fauth-Bühler, Mira, Papadopoulos, Dimitri, Gallinat, Jürgen, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Mann, Karl, Martinot, Jean-Luc, Paus, Tomáš, Pausova, Zdenka, Smolka, Michael, Ströhle, Andreas, Rietschel, Marcella, Flor, Herta, Schumann, Gunter, and Nees, Frauke

Published
2016
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12. Dimensions of Manic Symptoms in Youth: Psychosocial Impairment and Cognitive Performance in the IMAGEN Sample

Author

Stringaris, Argyris, Castellanos-Ryan, Natalie, Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L., Bromberg, Uli, Büchel, Christian, Fauth-Bühler, Mira, Flor, Herta, Frouin, Vincent, Gallinat, Juergen, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Itterman, Bernd, Lawrence, Claire, Nees, Frauke, Paillere-Martinot, Marie-Laure, Paus, Tomas, Pausova, Zdenka, Rietschel, Marcella, Smolka, Michael N., Schumann, Gunter, Goodman, Robert, and Conrod, Patricia

Abstract

Background: It has been reported that mania may be associated with superior cognitive performance. In this study, we test the hypothesis that manic symptoms in youth separate along two correlated dimensions and that a symptom constellation of high energy and cheerfulness is associated with superior cognitive performance. Method: We studied 1755 participants of the IMAGEN study, of average age 14.4 years (SD = 0.43), 50.7% girls. Manic symptoms were assessed using the Development and Wellbeing Assessment by interviewing parents and young people. Cognition was assessed using the Wechsler Intelligence Scale For Children (WISC-IV) and a response inhibition task. Results: Manic symptoms in youth formed two correlated dimensions: one termed "exuberance," characterized by high energy and cheerfulness and one of "undercontrol" with distractibility, irritability and risk-taking behavior. Only the undercontrol, but not the exuberant dimension, was independently associated with measures of psychosocial impairment. In multivariate regression models, the exuberant, but not the undercontrolled, dimension was positively and significantly associated with verbal IQ by both parent- and self-report; conversely, the undercontrolled, but not the exuberant, dimension was associated with poor performance in a response inhibition task. Conclusions: Our findings suggest that manic symptoms in youth may form dimensions with distinct correlates. The results are in keeping with previous findings about superior performance associated with mania. Further research is required to study etiological differences between these symptom dimensions and their implications for clinical practice.

Published
2014
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15. Correlated gene expression supports synchronous activity in brain networks

Author

IMAGEN consortium, Richiardi, Jonas, Altmann, Andre, Milazzo, Anna-Clare, Chang, Catie, Chakravarty, M. Mallar, Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L.W., Bromberg, Uli, Büchel, Christian, Conrod, Patricia, Fauth-Bühler, Mira, Flor, Herta, Frouin, Vincent, Gallinat, Jürgen, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Lemaître, Hervé, Mann, Karl F., Martinot, Jean-Luc, Nees, Frauke, Paus, Tomáš, Pausova, Zdenka, Rietschel, Marcella, Robbins, Trevor W., Smolka, Michael N., Spanagel, Rainer, Ströhle, Andreas, Schumann, Gunter, Hawrylycz, Mike, Poline, Jean-Baptiste, and Greicius, Michael D.

Published
2015

17. RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release

Author

Stacey, David, Bilbao, Ainhoa, Maroteaux, Matthieu, Jia, Tianye, Easton, Alanna C., Longueville, Sophie, Nymberg, Charlotte, Banaschewski, Tobias, Barker, Gareth J., Büchel, Christian, Carvalho, Fabiana, Conrod, Patricia J., Desrivières, Sylvane, Fauth-Bühler, Mira, Fernandez-Medarde, Alberto, Flor, Herta, Gallinat, Jürgen, Garavan, Hugh, Bokde, Arun L. W., Heinz, Andreas, Ittermann, Bernd, Lathrop, Mark, Lawrence, Claire, Loth, Eva, Lourdusamy, Anbarasu, Mann, Karl F., Martinot, Jean-Luc, Nees, Frauke, Palkovits, Miklós, Paus, Tomas, Pausova, Zdenka, Rietschel, Marcella, Ruggeri, Barbara, Santos, Eugenio, Smolka, Michael N., Staehlin, Oliver, Jarvelin, Marjo-Riitta, Elliott, Paul, Sommer, Wolfgang H., Mameli, Manuel, Müller, Christian P., Spanagel, Rainer, Girault, Jean-Antoine, and Schumann, Gunter

Published
2012

18. Personality and Substance Use: Psychometric Evaluation and Validation of the Substance Use Risk Profile Scale (SURPS) in English, Irish, French, and German Adolescents

Author

Jurk, Sarah, Kuitunen-Paul, Sören, Kroemer, Nils B., Artiges, Eric, Banaschewski, Tobias, Bokde, Arun L. W., Büchel, Christian, Conrod, Patricia, Fauth-Bühler, Mira, Flor, Herta, Frouin, Vincent, Gallinat, Jürgen, Garavan, Hugh, Heinz, Andreas, Mann, Karl F., Nees, Frauke, Paus, Tomáš, Pausova, Zdenka, Poustka, Luise, Rietschel, Marcella, Schumann, Gunter, Struve, Maren, and Smolka, Michael N.

Published
2015
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19. BRAIN NETWORKS: Correlated gene expression supports synchronous activity in brain networks

Author

Richiardi, Jonas, Altmann, Andre, Milazzo, Anna-Clare, Chang, Catie, Chakravarty, Mallar M., Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L.W., Bromberg, Uli, Biichel, Christian, Conrod, Patricia, Fauth-Bühler, Mira, Flor, Herta, Frouin, Vincent, Gallinat, Jürgen, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Lemaitre, Hervé, Mann, Karl F., Martinot, Jean-Luc, Nees, Frauke, Paus, Tomáš, Pausova, Zdenka, Rietschel, Marcella, Robbins, Trevor W., Smolka, Michael N., Spanagel, Rainer, Ströhle, Andreas, Schumann, Gunter, Hawrylycz, Mike, Poline, Jean-Baptiste, Greicius, Michael D., and consortium, IMAGEN

Published
2015
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20. No differences in ventral striatum responsivity between adolescents with a positive family history of alcoholism and controls

Author

Müller, Kathrin U., Gan, Gabriela, Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L. W., Büchel, Christian, Conrod, Patricia, Fauth-Bühler, Mira, Flor, Herta, Gallinat, Jürgen, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Lawrence, Claire, Loth, Eva, Mann, Karl, Martinot, Jean-Luc, Nees, Frauke, Paus, Tomáš, Pausova, Zdenka, Rietschel, Marcella, Ströhle, Andreas, Struve, Maren, Schumann, Gunter, and Smolka, Michael N.

Published
2015
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21. Differential predictors for alcohol use in adolescents as a function of familial risk

Author

Tschorn, Mira, Lorenz, Robert C., O’Reilly, Paul F., Reichenberg, Abraham, Quinlan, Erin B., Flor, Herta, Grigis, Antoine, Garavan, Hugh, Ittermann, Bernd, Papadopoulos Orfanos, Dimitri, Poustka, Luise, Millenet, Sabina, Smolka, Michael N., Whelan, Robert, Schumann, Gunter, Rapp, Michael A., Robbins, Trevor, Dalley, Jeffrey, Subramaniam, Naresh, Theobald, David, Mann, Karl, Bach, Christiane, Struve, Maren, Banaschewski, Tobias, Rietschel, Marcella, Spanagel, Rainer, Nees, Frauke, Fauth-Bühler, Mira, Grimmer, Yvonne, Lathrop, Mark, Heinz, Andreas, Albrecht, Lisa, Ivanov, Nikolay, Strache, Nicole, Rapp, Michael, Ströhle, Andreas, Reuter, Jan, Gallinat, Jürgen, Walter, Henrik, Gemmeke, Isabel, Genauck, Alexander, Parchetka, Caroline, Weiß, Katharina, Kruschwitz, Johann, Raffaelli, Bianca, Isci, Alev, Daedelow, Laura, Barbot, Alexis, Thyreau, Benjamin, Schwartz, Yannick, Lalanne, Christophe, Frouin, Vincent, Orfanos, Dimitri Papadopoulos, Rogers, John, Ireland, James, Lanzerath, Dirk, Feng, Jianfeng, Martinot, Jean-Luc, Bricaud, Zuleima, Briand, Fanny Gollier, LemaÎtre, Hervé, Miranda, Ruben, Artiges, Eric, Massicotte, Jessica, Martinot, Marie-Laure Paillère, Vulser, Helene, Pentillä, Jani, Filippi, Irina, Galinowski, André, Bezivin, Pauline, Cattrell, Anna, Jia, Tianye, Desrivières, Sylvane, Werts, Helen, Topper, Lauren, Reed, Laurence, Andrew, Chris, Mallik, Catherine, Ruggeri, Barbara, Nymberg, Charlotte, Barker, Gareth, Conrod, Patricia J., Smith, Lindsay, Loth, Eva, Havatzias, Stephanie, Shekarrizi, Sheyda, Kitson, Emily, Robinson, Alice, Hall, Deborah, Rubino, Chiara, Wright, Hannah, Stueber, Kerstin, Hanratty, Eanna, Kennedy, Eleanor, De Carvahlo, Fabiana Mesquita, Stringaris, Argyris, Robert, Gabriel, Ing, Alex, Macare, Christine, Xu, Bing, Yu, Tao, Quinlan, Erin Burke, Constant, Patrick, Aydin, Semiha, Brühl, Ruediger, Ihlenfeld, Albrecht, Walaszek, Bernadeta, Smolka, Michael, Hübner, Thomas, Müller, Kathrin, Ripke, Stephan, Jurk, Sarah, Mennigen, Eva, Schmidt, Dirk, Vetter, Nora, Ziesch, Veronika, Fröhner, Juliane H., Bokde, Arun L. W., Carter, Daniel, Walsh, Emily, O’Driscoll, Susanne, Agan, Maria Leonora Fatimah, McMorrow, Mairead, Nugent, Sinead, Connolly, Colm, Dooley, Eoin, Cremen, Clodagh, Jones, Jennifer, O’Keefe, John, O’Connor, Martin, Poline, Jean-Baptiste, Büchel, Christian, Bromberg, Uli, Fadai, Tahmine, Yacubian, Juliana, Schneider, Sophia, Lobatchewa, Maria, Lawrence, Claire, Newman, Craig, Head, Kay, Heym, Nadja, Gowland, Penny, Stedman, Alicia, Kaviani, Mehri, Taplin, Susannah, Stephens, Dai, Paus, Tomáš, Pausova, Zdenka, Tahmasebi, Amir, Banaschewski, Tobias [0000-0003-4595-1144], Bokde, Arun L. W. [0000-0003-0114-4914], Quinlan, Erin B. [0000-0003-2927-1632], Desrivières, Sylvane [0000-0002-9120-7060], Gowland, Penny [0000-0002-4900-4817], Martinot, Jean-Luc [0000-0002-0136-0388], Artiges, Eric [0000-0003-4461-7646], Nees, Frauke [0000-0002-7796-8234], Papadopoulos Orfanos, Dimitri [0000-0002-1242-8990], Fröhner, Juliane H. [0000-0002-8493-6396], Smolka, Michael N. [0000-0001-5398-5569], Walter, Henrik [0000-0002-9403-6121], Heinz, Andreas [0000-0001-5405-9065], Rapp, Michael A. [0000-0003-0106-966X], and Apollo - University of Cambridge Repository

Subjects
631/208, article, 59/36, 45/23, 631/378, 631/477, 692/699/476/5
Abstract

Traditional models of future alcohol use in adolescents have used variable-centered approaches, predicting alcohol use from a set of variables across entire samples or populations. Following the proposition that predictive factors may vary in adolescents as a function of family history, we used a two-pronged approach by first defining clusters of familial risk, followed by prediction analyses within each cluster. Thus, for the first time in adolescents, we tested whether adolescents with a family history of drug abuse exhibit a set of predictors different from adolescents without a family history. We apply this approach to a genetic risk score and individual differences in personality, cognition, behavior (risk-taking and discounting) substance use behavior at age 14, life events, and functional brain imaging, to predict scores on the alcohol use disorders identification test (AUDIT) at age 14 and 16 in a sample of adolescents (N = 1659 at baseline, N = 1327 at follow-up) from the IMAGEN cohort, a longitudinal community-based cohort of adolescents. In the absence of familial risk (n = 616), individual differences in baseline drinking, personality measures (extraversion, negative thinking), discounting behaviors, life events, and ventral striatal activation during reward anticipation were significantly associated with future AUDIT scores, while the overall model explained 22% of the variance in future AUDIT. In the presence of familial risk (n = 711), drinking behavior at age 14, personality measures (extraversion, impulsivity), behavioral risk-taking, and life events were significantly associated with future AUDIT scores, explaining 20.1% of the overall variance. Results suggest that individual differences in personality, cognition, life events, brain function, and drinking behavior contribute differentially to the prediction of future alcohol misuse. This approach may inform more individualized preventive interventions.

Published
2021
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23. A target sample of adolescents and reward processing: same neural and behavioral correlates engaged in common paradigms?

Author

Nees, Frauke, Vollstädt-Klein, Sabine, Fauth-Bühler, Mira, Steiner, Sabina, Mann, Karl, Poustka, Luise, Banaschewski, Tobias, Büchel, Christian, Conrod, Patricia J., Garavan, Hugh, Heinz, Andreas, Ittermann, Bernd, Artiges, Eric, Paus, Tomas, Pausova, Zdenka, Rietschel, Marcella, Smolka, Michael N., Struve, Maren, Loth, Eva, Schumann, Gunter, Flor, Herta, and The IMAGEN Consortium

Published
2012
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25. Neuropsychosocial profiles of current and future adolescent alcohol misusers

Author

Whelan, Robert, Watts, Richard, Orr, Catherine A., Althoff, Robert R., Artiges, Eric, Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L. W., Büchel, Christian, Carvalho, Fabiana M., Conrod, Patricia J., Flor, Herta, Fauth-Bühler, Mira, Frouin, Vincent, Gallinat, Juergen, Gan, Gabriela, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Lawrence, Claire, Mann, Karl, Martinot, Jean-Luc, Nees, Frauke, Ortiz, Nick, Paillère-Martinot, Marie-Laure, Paus, Tomas, Pausova, Zdenka, Rietschel, Marcella, Robbins, Trevor W., Smolka, Michael N., Ströhle, Andreas, Schumann, Gunter, Garavan, Hugh, Albrecht, Lisa, Arroyo, Mercedes, Aydin, Semiha, Bach, Christine, Barbot, Alexis, Bricaud, Zuleima, Bromberg, Uli, Bruehl, Ruediger, Cattrell, Anna, Czech, Katharina, Dalley, Jeffrey, Desrivieres, Sylvane, Fadai, Tahmine, Fuchs, Birgit, Briand, Fanny Gollier, Head, Kay, Heinrichs, Bert, Heym, Nadja, Hübner, Thomas, Ihlenfeld, Albrecht, Ireland, James, Ivanov, Nikolay, Jia, Tianye, Jones, Jennifer, Kepa, Agnes, Lanzerath, Dirk, Lathrop, Mark, Lemaitre, Hervé, Lüdemann, Katharina, Martinez-Medina, Lourdes, Mignon, Xavier, Miranda, Ruben, Müller, Kathrin, Nymberg, Charlotte, Pentilla, Jani, Poline, Jean-Baptiste, Poustka, Luise, Rapp, Michael, Ripke, Stephan, Rodehacke, Sarah, Rogers, John, Romanowski, Alexander, Ruggeri, Barbara, Schmäl, Christine, Schmidt, Dirk, Schneider, Sophia, Schroeder, Markus, Schubert, Florian, Sommer, Wolfgang, Spanagel, Rainer, Stacey, David, Steiner, Sabina, Stephens, Dai, Strache, Nicole, Struve, Maren, Tahmasebi, Amir, Topper, Lauren, Vulser, Helene, Walaszek, Bernadeta, Werts, Helen, Williams, Steve, Wong, Peng C., Yacubian, Juliana, and Ziesch., Veronika

Published
2014
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26. Do You See What I See? Sex Differences in the Discrimination of Facial Emotions During Adolescence

Author

Lee, Nikki C., Krabbendam, Lydia, White, Thomas P., Meeter, Martijn, Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L. W., Büchel, Christian, Conrod, Patricia, Flor, Herta, Frouin, Vincent, Heinz, Andreas, Garavan, Hugh, Gowland, Penny, Ittermann, Bernd, Mann, Karl, Martinot, Marie-Laure Paillère, Nees, Frauke, Paus, Tomas, Pausova, Zdenka, Rietschel, Marcella, Robbins, Trevor, Fauth-Bühler, Mira, Smolka, Michael N., Gallinat, Juergen, Schumann, Gunther, and Shergill, Sukhi S.

Published
2013
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27. Neural Correlates of Adolescent Irritability and Its Comorbidity With Psychiatric Disorders

Author

Chaarani, Bader, primary, Kan, Kees-Jan, additional, Mackey, Scott, additional, Spechler, Philip A., additional, Potter, Alexandra, additional, Banaschewski, Tobias, additional, Millenet, Sabina, additional, Bokde, Arun L.W., additional, Bromberg, Uli, additional, Büchel, Christian, additional, Cattrell, Anna, additional, Conrod, Patricia J., additional, Desrivières, Sylvane, additional, Flor, Herta, additional, Frouin, Vincent, additional, Gallinat, Jürgen, additional, Gowland, Penny, additional, Heinz, Andreas, additional, Ittermann, Bernd, additional, Martinot, Jean-Luc, additional, Nees, Frauke, additional, Paus, Tomáš, additional, Poustka, Luise, additional, Smolka, Michael N., additional, Walter, Henrik, additional, Whelan, Robert, additional, Stringaris, Argyris, additional, Higgins, Stephen T., additional, Schumann, Gunter, additional, Garavan, Hugh, additional, Althoff, Robert R., additional, Rapp, Dr. Michael, additional, Artiges, Dr. Eric, additional, Schneider, Sophia, additional, Bach, Christine, additional, Paus, Dr. Tomas, additional, Barbot, Alexis, additional, Barker, Dr. Gareth, additional, Bokde, Dr. Arun, additional, Vetter, Dr. Nora, additional, Büchel, Dr. Christian, additional, Cattrell, Dr. Anna, additional, Constant, Patrick, additional, Crombag, Dr. Hans, additional, Czech, Katharina, additional, Dalley, Dr. Jeffrey, additional, Decideur, Benjamin, additional, Spranger, Tade, additional, Ripley, Dr. Tamzin, additional, Heym, Dr. Nadja, additional, Sommer, Dr. Wolfgang, additional, Fuchs, Birgit, additional, Gallinat, Dr. Jürgen, additional, Garavan, Dr. Hugh, additional, Spanagel, Dr. Rainer, additional, Kaviani, Mehri, additional, Heinrichs, Dr. Bert, additional, Heinz, Dr. Andreas, additional, Subramaniam, Naresh, additional, Jia, Dr. Tianye, additional, Ihlenfeld, Albrecht, additional, Ireland, James, additional, Ittermann, Dr. Bernd, additional, Conrod, Dr. Patricia, additional, Banaschewski, Dr. Tobias, additional, Jones, Jennifer, additional, Klaassen, Dr. Arno, additional, Lalanne, Christophe, additional, Lanzerath, Dr. Dirk, additional, Lawrence, Dr. Claire, additional, Lemaitre, Dr. Hervé, additional, Desrivieres, Dr. Sylvane, additional, Mallik, Catherine, additional, Mann, Dr. Karl, additional, Mar, Dr. Adam, additional, Martinez-Medina, Lourdes, additional, Martinot, Dr. Jean-Luc, additional, Mennigen, Eva, additional, Mesquita de Carvahlo, Dr. Fabiana, additional, Schwartz, Yannick, additional, Bruehl, Dr. Ruediger, additional, Müller, Kathrin, additional, Nymberg, Charlotte, additional, Lathrop, Dr. Mark, additional, Robbins, Dr. Trevor, additional, Pausova, Dr. Zdenka, additional, Pentilla, Dr. Jani, additional, Biondo, Dr. Francesca, additional, Poline, Dr. Jean-Baptiste, additional, Poustka, Dr. Luise, additional, Smolka, Dr. Michael, additional, Fröhner, Juliane, additional, Struve, Dr. Maren, additional, Williams, Dr. Steve, additional, Hübner, Dr. Thomas, additional, Aydin, Semiha, additional, Rogers, John, additional, Romanowski, Alexander, additional, Schmäl, Dr. Christine, additional, Schmidt, Dirk, additional, Ripke, Stephan, additional, Arroyo, Dr. Mercedes, additional, Schubert, Dr. Florian, additional, Pena-Oliver, Dr. Yolanda, additional, Fauth-Bühler, Mira, additional, Mignon, Xavier, additional, Whelan, Dr. Robert, additional, Speiser, Dr. Claudia, additional, Fadai, Tahmine, additional, Stephens, Dr. Dai, additional, Ströhle, Dr. Andreas, additional, Paillere, Dr. Marie-Laure, additional, Strache, Nicole, additional, Theobald, David, additional, Jurk, Sarah, additional, Vulser, Dr. Helene, additional, Miranda, Ruben, additional, Yacubilin, Dr. Juliana, additional, Genauck, Alexander, additional, Parchetka, Caroline, additional, Gemmeke, Isabel, additional, Kruschwitz, Johann, additional, Weiss, Katharina, additional, Walter, Dr. Henrik, additional, Feng, Jianfeng, additional, Papadopoulos, Dimitri, additional, Filippi, Irina, additional, Ing, Alex, additional, Ruggeri, Dr. Barbara, additional, Xu, Bing, additional, Macare, Christine, additional, Chu, Dr. Congying, additional, Hanratty, Eanna, additional, Burke Quinlan, Dr. Erin, additional, Robert, Dr. Gabriel, additional, Schumann, Dr. Gunter, additional, Yu, Dr. Tao, additional, Ziesch, Veronika, additional, and Stedman, Alicia, additional

Published
2020
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28. From gene to brain to behavior: schizophrenia-associated variation in AMBRA1 alters impulsivity-related traits

Author

Heinrich, Angela, Nees, Frauke, Lourdusamy, Anbarasu, Tzschoppe, Jelka, Meier, Sandra, Vollstädt-Klein, Sabine, Fauth-Bühler, Mira, Steiner, Sabina, Bach, Christiane, Poustka, Luise, Banaschewski, Tobias, Barker, Gareth J., Büchel, Christian, Conrod, Patricia J., Garavan, Hugh, Gallinat, Jürgen, Heinz, Andreas, Ittermann, Bernd, Loth, Eva, Mann, Karl, Artiges, Eric, Paus, Tomáš, Lawrence, Claire, Pausova, Zdenka, Smolka, Michael N., Ströhle, Andreas, Struve, Maren, Witt, Stephanie H., Schumann, Gunter, Flor, Herta, and Rietschel, Marcella

Published
2013
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29. Altered Reward Processing in Adolescents With Prenatal Exposure to Maternal Cigarette Smoking

Author

Müller, Kathrin U., Mennigen, Eva, Ripke, Stephan, Banaschewski, Tobias, Barker, Gareth J., Büchel, Christian, Conrod, Patricia, Fauth-Bühler, Mira, Flor, Herta, Garavan, Hugh, Heinz, Andreas, Lawrence, Claire, Loth, Eva, Mann, Karl, Martinot, Jean-Luc, Pausova, Zdenka, Rietschel, Marcella, Ströhle, Andreas, Struve, Maren, Walaszek, Bernadeta, Schumann, Gunter, Paus, Tomáš, and Smolka, Michael N.

Published
2013
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31. Cannabis-Associated Psychotic-like Experiences Are Mediated by Developmental Changes in the Parahippocampal Gyrus

Author

Yu, Tao, primary, Jia, Tianye, additional, Zhu, Liping, additional, Desrivières, Sylvane, additional, Macare, Christine, additional, Bi, Yan, additional, Bokde, Arun L.W., additional, Quinlan, Erin Burke, additional, Heinz, Andreas, additional, Ittermann, Bernd, additional, Liu, ChuanXin, additional, Ji, Lei, additional, Banaschewski, Tobias, additional, Ren, Decheng, additional, Du, Li, additional, Hou, Binyin, additional, Flor, Herta, additional, Frouin, Vincent, additional, Garavan, Hugh, additional, Gowland, Penny, additional, Martinot, Jean-Luc, additional, Paillère Martinot, Marie-Laure, additional, Nees, Frauke, additional, Orfanos, Dimitri Papadopoulos, additional, Luo, Qiang, additional, Chu, Congying, additional, Paus, Tomas, additional, Poustka, Luise, additional, Hohmann, Sarah, additional, Millenet, Sabina, additional, Smolka, Michael N., additional, Vetter, Nora C., additional, Mennigen, Eva, additional, Lei, Cai, additional, Walter, Henrik, additional, Fröhner, Juliane H., additional, Whelan, Robert, additional, He, Guang, additional, He, Lin, additional, Schumann, Gunter, additional, Robert, Gabriel, additional, Rapp, Michael, additional, Artiges, Eric, additional, Schneider, Sophia, additional, Bach, Christine, additional, Barbot, Alexis, additional, Barker, Gareth, additional, Bokde, Arun, additional, Vetter, Nora, additional, Büchel, Christian, additional, Cattrell, Anna, additional, Constant, Patrick, additional, Crombag, Hans, additional, Czech, Katharina, additional, Dalley, Jeffrey, additional, Decideur, Benjamin, additional, Spranger, Tade, additional, Ripley, Tamzin, additional, Heym, Nadja, additional, Sommer, Wolfgang, additional, Fuchs, Birgit, additional, Gallinat, Jürgen, additional, Spanagel, Rainer, additional, Kaviani, Mehri, additional, Heinrichs, Bert, additional, Subramaniam, Naresh, additional, Ihlenfeld, Albrecht, additional, Delosis, James Ireland, additional, Conrod, Patricia, additional, Jones, Jennifer, additional, Klaassen, Arno, additional, Lalanne, Christophe, additional, Lanzerath, Dirk, additional, Lawrence, Claire, additional, Lemaitre, Hervé, additional, Desrivieres, Sylvane, additional, Mallik, Catherine, additional, Mann, Karl, additional, Mar, Adam, additional, Martinez-Medina, Lourdes, additional, de Carvahlo, Fabiana Mesquita, additional, Schwartz, Yannick, additional, Bruehl, Ruediger, additional, Müller, Kathrin, additional, Nymberg, Charlotte, additional, Lathrop, Mark, additional, Robbins, Trevor, additional, Pausova, Zdenka, additional, Pentilla, Jani, additional, Biondo, Francesca, additional, Poline, Jean-Baptiste, additional, Smolka, Michael, additional, Fröhner, Juliane, additional, Struve, Maren, additional, Williams, Steve, additional, Hübner, Thomas, additional, Bromberg, Uli, additional, Aydin, Semiha, additional, Rogers, John, additional, Romanowski, Alexander, additional, Schmäl, Christine, additional, Schmidt, Dirk, additional, Ripke, Stephan, additional, Arroyo, Mercedes, additional, Schubert, Florian, additional, Pena-Oliver, Yolanda, additional, Fauth-Bühler, Mira, additional, Mignon, Xavier, additional, Speiser, Claudia, additional, Fadai, Tahmine, additional, Stephens, Dai, additional, Ströhle, Andreas, additional, Paillere, Marie-Laure, additional, Strache, Nicole, additional, Theobald, David, additional, Jurk, Sarah, additional, Vulser, Helene, additional, Miranda, Ruben, additional, Yacubilin, Juliana, additional, Genauck, Alexander, additional, Parchetka, Caroline, additional, Gemmeke, Isabel, additional, Kruschwitz, Johann, additional, WeiB, Katharina, additional, Feng, Jianfeng, additional, Papadopoulos, Dimitri, additional, Filippi, Irina, additional, Ing, Alex, additional, Ruggeri, Barbara, additional, Xu, Bing, additional, Hanratty, Eanna, additional, Yu, Tao, additional, Ziesch, Veronika, additional, and Stedman, Alicia, additional

Published
2020
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32. Structural brain correlates of adolescent resilience

Author

Burt, Keith B, Whelan, Robert, Conrod, Patricia J, Banaschewski, Tobias, Barker, Gareth J, Bokde, Arun LW, Bromberg, Uli, Büchel, Christian, Fauth-Bühler, Mira, Flor, Herta, Galinowski, André, Gallinat, Juergen, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Mann, Karl, Nees, Frauke, Papadopoulos-Orfanos, Dimitri, Paus, Tomas, Pausova, Zdenka, Poustka, Luise, Rietschel, Marcella, Robbins, Trevor W, Smolka, Michael N, Ströhle, Andreas, Schumann, Gunter, Garavan, Hugh, IMAGEN Consortium, Robbins, Trevor [0000-0003-0642-5977], and Apollo - University of Cambridge Repository

Subjects
Male, Adolescent, competence, IMAGEN study, Prefrontal Cortex, Resilience, Psychological, Imaging, Europe, Adaptation, Psychological, Humans, adolescence, Female, resilience, adversity, Stress, Psychological
Abstract

BACKGROUND: Despite calls for integration of neurobiological methods into research on youth resilience (high competence despite high adversity), we know little about structural brain correlates of resilient functioning. The aim of the current study was to test for brain regions uniquely associated with positive functioning in the context of adversity, using detailed phenotypic classification. METHODS: 1,870 European adolescents (Mage = 14.56 years, SDage = 0.44 years, 51.5% female) underwent MRI scanning and completed behavioral and psychological measures of stressful life events, academic competence, social competence, rule-abiding conduct, personality, and alcohol use. RESULTS: The interaction of competence and adversity identified two regions centered on the right middle and superior frontal gyri; grey matter volumes in these regions were larger in adolescents experiencing adversity who showed positive adaptation. Differences in these regions among competence/adversity subgroups were maintained after controlling for several covariates and were robust to alternative operationalization decisions for key constructs. CONCLUSIONS: We demonstrate structural brain correlates of adolescent resilience, and suggest that right prefrontal structures are implicated in adaptive functioning for youth who have experienced adversity.

Published
2018
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33. Low Smoking Exposure, the Adolescent Brain, and the Modulating Role of CHRNA5 Polymorphisms

Author

Chaarani, Bader, primary, Kan, Kees-Jan, additional, Mackey, Scott, additional, Spechler, Philip A., additional, Potter, Alexandra, additional, Orr, Catherine, additional, D’Alberto, Nicholas, additional, Hudson, Kelsey E., additional, Banaschewski, Tobias, additional, Bokde, Arun L.W., additional, Bromberg, Uli, additional, Büchel, Christian, additional, Cattrell, Anna, additional, Conrod, Patricia J., additional, Desrivières, Sylvane, additional, Flor, Herta, additional, Frouin, Vincent, additional, Gallinat, Jürgen, additional, Gowland, Penny, additional, Heinz, Andreas, additional, Ittermann, Bernd, additional, Martinot, Jean-Luc, additional, Nees, Frauke, additional, Papadopoulos-Orfanos, Dimitri, additional, Paus, Tomáš, additional, Poustka, Luise, additional, Smolka, Michael N., additional, Walter, Henrik, additional, Whelan, Robert, additional, Higgins, Stephen T., additional, Schumann, Gunter, additional, Althoff, Robert R., additional, Stein, Elliot A., additional, Garavan, Hugh, additional, Mann, Karl, additional, Struve, Maren, additional, Rietschel, Marcella, additional, Spanagel, Rainer, additional, Fauth-Bühler, Mira, additional, Millenet, Sabina, additional, Grimmer, Yvonne, additional, Ivanov, Nikolay, additional, Strache, Nicole, additional, Rapp, Michael, additional, Ströhle, Andreas, additional, Reuter, Jan, additional, Barbot, Alexis, additional, Thyreau, Benjamin, additional, Schwartz, Yannick, additional, Lalanne, Christophe, additional, Bricaud, Zuleima, additional, Briand, Fanny Gollier, additional, Lemaitre, Hervé, additional, Massicotte, Jessica, additional, Vulser, Helene, additional, Pentillä, Jani, additional, Galinowski, André, additional, Jia, Tianye, additional, Werts, Helen, additional, Topper, Lauren, additional, Reed, Laurence, additional, Andrew, Chris, additional, Mallik, Catherine, additional, Ruggeri, Barbara, additional, Nymberg, Charlotte, additional, Smith, Lindsay, additional, Loth, Eva, additional, Havatzias, Stephanie, additional, Stueber, Kerstin, additional, Stringaris, Argyris, additional, Constant, Patrick, additional, Brühl, Ruediger, additional, Ihlenfeld, Albrecht, additional, Walaszek, Bernadeta, additional, Hübner, Thomas, additional, Müller, Kathrin, additional, Ripke, Stephan, additional, Rodehacke, Sarah, additional, Mennigen, Eva, additional, Schmidt, Dirk, additional, Vetter, Nora, additional, Ziesch, Veronika, additional, Jones, Jennifer, additional, Poline, Jean-Baptiste, additional, Fadai, Tahmine, additional, Yacubian, Juliana, additional, Schneider, Sophia, additional, Lawrence, Claire, additional, Newman, Craig, additional, Head, Kay, additional, Heym, Nadja, additional, Pausova, Zdenka, additional, and Tahmasebi, Amir, additional

Published
2019
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36. Pathological gambling: a review of the neurobiological evidence relevant for its classification as an addictive disorder.

Author

Fauth‐Bühler, Mira, Mann, Karl, Potenza, Marc N., and Fauth-Bühler, Mira

Subjects
*COMPULSIVE gambling, *IMPULSE control disorders, *SUBSTANCE-induced disorders, *OBSESSIVE-compulsive disorder, *COMPULSIVE behavior, *GAMBLING, *NEUROBIOLOGY, *NOSOLOGY, *RESEARCH funding, INTERNATIONAL Statistical Classification of Diseases & Related Health Problems
Abstract

In light of the upcoming eleventh edition of the International Classification of Diseases (ICD-11), the question arises as to the most appropriate classification of 'Pathological Gambling' ('PG'). Some academic opinion favors leaving PG in the 'Impulse Control Disorder' ('ICD') category, as in ICD-10, whereas others argue that new data especially from the neurobiological area favor allocating it to the category of 'Substance-related and Addictive Disorders' ('SADs'), following the decision in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders. The current review examines important findings in relation to PG, with the aim of enabling a well-informed decision to be made with respect to the classification of PG as a SAD or ICD in ICD-11. Particular attention is given to cognitive deficits and underlying neurobiological mechanisms that play a role in SADs and ICDs. These processes are impulsivity, compulsivity, reward/punishment processing and decision-making. In summary, the strongest arguments for subsuming PG under a larger SAD category relate to the existence of similar diagnostic characteristics; the high co-morbidity rates between the disorders; their common core features including reward-related aspects (positive reinforcement: behaviors are pleasurable at the beginning which is not the case for ICDs); the findings that the same brain structures are involved in PG and SADs, including the ventral striatum. Research on compulsivity suggests a relationship with PG and SAD, particularly in later stages of the disorders. Although research is limited for ICDs, current data do not support continuing to classify PG as an ICD. [ABSTRACT FROM AUTHOR]

Published
2017
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37. Gaming disorder: Its delineation as an important condition for diagnosis, management, and prevention

Author

Saunders, John B., primary, Hao, Wei, additional, Long, Jiang, additional, King, Daniel L., additional, Mann, Karl, additional, Fauth-Bühler, Mira, additional, Rumpf, Hans-Jürgen, additional, Bowden-Jones, Henrietta, additional, Rahimi-Movaghar, Afarin, additional, Chung, Thomas, additional, Chan, Elda, additional, Bahar, Norharlina, additional, Achab, Sophia, additional, Lee, Hae Kook, additional, Potenza, Marc, additional, Petry, Nancy, additional, Spritzer, Daniel, additional, Ambekar, Atul, additional, Derevensky, Jeffrey, additional, Griffiths, Mark D., additional, Pontes, Halley M., additional, Kuss, Daria, additional, Higuchi, Susumu, additional, Mihara, Satoko, additional, Assangangkornchai, Sawitri, additional, Sharma, Manoj, additional, Kashef, Ahmad El, additional, Ip, Patrick, additional, Farrell, Michael, additional, Scafato, Emanuele, additional, Carragher, Natacha, additional, and Poznyak, Vladimir, additional

Published
2017
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38. Dimensions of manic symptoms in youth:psychosocial impairment and cognitive performance in the IMAGEN sample

Author

Stringaris, Argyris, Castellanos-Ryan, Natalie, Banaschewski, Tobias, Barker, Gareth J, Bokde, Arun L, Bromberg, Uli, Büchel, Christian, Fauth-Bühler, Mira, Flor, Herta, Frouin, Vincent, Gallinat, Juergen, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Itterman, Bernd, Lawrence, Claire, Nees, Frauke, Paillere-Martinot, Marie-Laure, Paus, Tomas, Pausova, Zdenka, Rietschel, Marcella, Smolka, Michael N, Schumann, Gunter, Goodman, Robert, and Conrod, Patricia

Subjects
Male, Bipolar Disorder, Adolescent, Intelligence, Original Articles, behavioral disciplines and activities, bipolar, Mania, Inhibition, Psychological, mental disorders, Humans, Female, adolescents, creativity, Psychomotor Performance
Abstract

BackgroundIt has been reported that mania may be associated with superior cognitive performance. In this study, we test the hypothesis that manic symptoms in youth separate along two correlated dimensions and that a symptom constellation of high energy and cheerfulness is associated with superior cognitive performance.MethodWe studied 1755 participants of the IMAGEN study, of average age 14.4 years (SD = 0.43), 50.7% girls. Manic symptoms were assessed using the Development and Wellbeing Assessment by interviewing parents and young people. Cognition was assessed using the Wechsler Intelligence Scale For Children (WISC-IV) and a response inhibition task.ResultsManic symptoms in youth formed two correlated dimensions: one termed exuberance, characterized by high energy and cheerfulness and one of undercontrol with distractibility, irritability and risk-taking behavior. Only the undercontrol, but not the exuberant dimension, was independently associated with measures of psychosocial impairment. In multivariate regression models, the exuberant, but not the undercontrolled, dimension was positively and significantly associated with verbal IQ by both parent- and self-report; conversely, the undercontrolled, but not the exuberant, dimension was associated with poor performance in a response inhibition task.ConclusionsOur findings suggest that manic symptoms in youth may form dimensions with distinct correlates. The results are in keeping with previous findings about superior performance associated with mania. Further research is required to study etiological differences between these symptom dimensions and their implications for clinical practice.

Published
2014

43. Abnormalities of functional brain networks in pathological gambling: a graph-theoretical approach

Author

Tschernegg, Melanie, Crone, Julia S., Eigenberger, Tina, Schwartenbeck, Philipp, Fauth-Bühler, Mira, Lemènager, Tagrid, Mann, Karl, Thon, Natasha, Wurst, Friedrich M., and Kronbichler, Martin

Subjects
small world, graph theory, connectivity, fMRI, network, pathological gambling, reward, Neuroscience, behavioral addiction
Abstract

Functional neuroimaging studies of pathological gambling (PG) demonstrate alterations in frontal and subcortical regions of the mesolimbic reward system. However, most investigations were performed using tasks involving reward processing or executive functions. Little is known about brain network abnormalities during task-free resting state in PG. In the present study, graph-theoretical methods were used to investigate network properties of resting state functional magnetic resonance imaging data in PG. We compared 19 patients with PG to 19 healthy controls (HCs) using the Graph Analysis Toolbox (GAT). None of the examined global metrics differed between groups. At the nodal level, pathological gambler showed a reduced clustering coefficient in the left paracingulate cortex and the left juxtapositional lobe (supplementary motor area, SMA), reduced local efficiency in the left SMA, as well as an increased node betweenness for the left and right paracingulate cortex and the left SMA. At an uncorrected threshold level, the node betweenness in the left inferior frontal gyrus was decreased and increased in the caudate. Additionally, increased functional connectivity between fronto-striatal regions and within frontal regions has also been found for the gambling patients. These findings suggest that regions associated with the reward system demonstrate reduced segregation but enhanced integration while regions associated with executive functions demonstrate reduced integration. The present study makes evident that PG is also associated with abnormalities in the topological network structure of the brain during rest. Since alterations in PG cannot be explained by direct effects of abused substances on the brain, these findings will be of relevance for understanding functional connectivity in other addictive disorders.

Published
2013
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44. Frontal cortex gray matter volume alterations in pathological gambling occur independently from substance use disorder.

Author

Zois, Evangelos, Kiefer, Falk, Lemenager, Tagrid, Vollstädt ‐ Klein, Sabine, Mann, Karl, and Fauth ‐ Bühler, Mira

Subjects
GAMBLING & psychology, SUBSTANCE-induced disorders, BRAIN anatomy, GRAY matter (Nerve tissue), NEUROTOXIC agents, COMORBIDITY, ANTHROPOMETRY, FRONTAL lobe, GAMBLING, MAGNETIC resonance imaging, PSYCHOMETRICS, SUBSTANCE abuse
Abstract

Neuroimaging in pathological gambling (PG) allows studying brain structure independent of pharmacological/neurotoxic effects occurring in substance addiction. Because of high comorbidity of PG with substance use disorder (SUD), first results on structural deficits in PG are controversial. The current investigation is the first to examine gray matter (GM) volume alterations in PG controlling for the impact of SUD by comparing non-comorbid (PGPURE ) and two comorbid (PGALCOHOL and PGPOLY ) groups. Two hundred and five individuals were included in the analysis: 107 patients diagnosed with PG and 98 healthy controls (HCs). We employed voxel-based morphometry to look for GM volume differences between the groups controlling for age, smoking and depression. GM decreases in the superior medial and orbital frontal cortex occur independently of substance use in PGPURE compared with HCs. The frontal pattern of GM decrease was comparable with PGALCOHOL group where additionally GM volume was decreased in the anterior cingulate but increased in the amygdala. Moreover, regions in PGALCOHOL + POLY with reduced GM volume were the medial frontal, anterior cingulate and occipital lobe regions. PGALCOHOL + POLY not only exhibited structural deficits in comparison with HCs but also relative to PGPURE in the precuneus and post-central gyrus. We demonstrated specific frontal cortex GM deficits in PG without SUD comorbidities. Whereas some target regions reported in earlier studies might result from comorbid substance abuse, there seems to be a core set of frontal alterations associated with addicted gambling behaviour independent of toxic substance effects. [ABSTRACT FROM AUTHOR]

Published
2017
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45. German Guidelines on Screening, Diagnosis and Treatment of Alcohol Use Disorders.

Author

Mann, Karl, Batra, anil, Fauth-Bühler, Mira, and Hoch, Eva

Subjects
ALCOHOL drinking & health, TOBACCO use, DECISION making in clinical medicine, EVIDENCE-based medicine, ALCOHOL-induced disorders, DIAGNOSIS, THERAPEUTICS
Abstract

Evidence-based strategies for screening, diagnosing and treating alcohol use disorders (AUD) are instrumental in the early and better management of individuals at risk for or suffering from AUD. However, existing guidelines vary and may be biased by conflicts of interests. Unbiased recommendations can be achieved only if sufficient detail is provided on the composition and representativeness of author groups, methodological rigor, handling of potential conflicts of interest and financing. This paper presents the first evidence-based guidelines for AUD from German-speaking countries. These guidelines are based on the work of delegates from a representative sample of 46 scientific societies (mostly medical) from Austria, Germany and Switzerland dealing with AUD. It also included patients and relatives. Recommendations were derived from a standardised hierarchical process involving quality controls drawn from existing guidelines, de novo literature searches and/or expert experience. Potential conflicts of interest were assessed yearly and led to exclusion from voting in specific areas. An overall cost of more than 400,000€ (for alcohol and tobacco guidelines) were exclusively covered by the participating societies and academic institutions. More than 100 recommendations on screening, diagnostics and treatment of AUD are outlined in this paper, and their scientific background is given in the online supplementary material. Tables of aggregated study synopses (in English) and the full version of guidelines (in German) are available (see "Links"). [ABSTRACT FROM AUTHOR]

Published
2017
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49. Genomic architecture of human neuroanatomical diversity

Author

Toro, Roberto, primary, Poline, Jean-Baptiste, additional, Huguet, Guillaume, additional, Loth, Eva, additional, Frouin, Vincent, additional, Banaschewski, Tobias, additional, Barker, Gareth J, additional, Bokde, Arun, additional, Büchel, Christian, additional, Carvalho, Fabiana, additional, Conrod, Patricia, additional, Fauth-Bühler, Mira, additional, Flor, Herta, additional, Gallinat, Jürgen, additional, Garavan, Hugh, additional, Gowloan, Penny, additional, Heinz, Andreas, additional, Ittermann, Bernd, additional, Lawrence, Claire, additional, Lemaître, Hervé, additional, Mann, Karl, additional, Nees, Frauke, additional, Paus, Tomáš, additional, Pausova, Zdenka, additional, Rietschel, Marcella, additional, Robbins, Trevor, additional, Smolka, Michael, additional, Ströhle, Andreas, additional, Schumann, Gunter, additional, and Bourgeron, Thomas, additional

Published
2013
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50. Structural brain correlates of adolescent resilience.

Author

Burt, Keith B., Whelan, Robert, Conrod, Patricia J., Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L.W., Bromberg, Uli, Büchel, Christian, Fauth‐Bühler, Mira, Flor, Herta, Galinowski, André, Gallinat, Juergen, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Mann, Karl, Nees, Frauke, Papadopoulos‐Orfanos, Dimitri, Paus, Tomas, and Pausova, Zdenka

Subjects
BRAIN physiology, ACADEMIC achievement, ADAPTABILITY (Personality), ALCOHOL drinking, MAGNETIC resonance imaging, PERSONALITY, QUESTIONNAIRES, PSYCHOLOGICAL resilience, SOCIAL skills, PHENOTYPES, CROSS-sectional method, ADOLESCENCE
Abstract

Background: Despite calls for integration of neurobiological methods into research on youth resilience (high competence despite high adversity), we know little about structural brain correlates of resilient functioning. The aim of the current study was to test for brain regions uniquely associated with positive functioning in the context of adversity, using detailed phenotypic classification. Methods: 1,870 European adolescents (Mage = 14.56 years, SDage = 0.44 years, 51.5% female) underwent MRI scanning and completed behavioral and psychological measures of stressful life events, academic competence, social competence, rule-abiding conduct, personality, and alcohol use. Results: The interaction of competence and adversity identified two regions centered on the right middle and superior frontal gyri; grey matter volumes in these regions were larger in adolescents experiencing adversity who showed positive adaptation. Differences in these regions among competence/adversity subgroups were maintained after controlling for several covariates and were robust to alternative operationalization decisions for key constructs. Conclusions: We demonstrate structural brain correlates of adolescent resilience, and suggest that right prefrontal structures are implicated in adaptive functioning for youth who have experienced adversity. [ABSTRACT FROM AUTHOR]

Published
2016
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