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1. Aminoácidos urinarios en recién nacidos pretérmino y pequeños para la edad gestacional durante el primer mes de vida

Author

Jiménez Torres, J., Faus, O., Vázquez, J., Bayes, R., Maldonado, J., Gil, A., and Faus, M.J.

Abstract

Se ha estudiado la evolución, a lo largo del primer mes de vida, de la excreción urinaria de una serie de aminoácidos que son importantes como parámetros bioquímico-nutricionales, en 41 niños prematuros y pequeños para la edad gestacional o distróficos, estudiándose también los índices más utilizados para establecer una situación de malnutrición. Todos los recien nacidos evolucionaron satisfactoriamente, presentando un crecimiento normal y unos parámetros biológicos adecuados. La excreción de 3-metil-Histidina y Glicocola aumenta a lo largo del tiempo, lo que indica que los niños distróficos están recibiendo una ingesta adecuada para su recuperación. Los niños prematuros presentan un aumento significativo en la excreción de Alanina, probablemente debido a un fallo en su metabolización. Los aminoácidos ramificados neutros presentan un aumento en la excreción con respecto al momento del nacimiento en los niños distróficos, lo que parece indicar una normalización del metabolismo muscular de estos niños. El índice BCA está disminuido a los 15 días en los niños distróficos con respecto a los prematuros, lo que indica el carácter de malnutridos de los primeros, recuperándose en ambos favorablemente al mes de vida. Igual recuperación se observa en el índice Glicocola/Valina., The evolution of a series of aminoacids in urinary excretion, important as biochemical-nutritional parameters, has been studied in 41 preterm and lowbirth-weight infants during the first month of life. Index commonly used as indicators of malnutriton have also been studied. All the infants who have been studied, had a satisfactory evolution, pfesenting normal growth and adequate biological parameters. The excretion of 3-metyl-His and Gly, increases progressively with time, which indicates that the low-birth-weight infants are receiving an adequate in take for recovery. . The preterm infants present a significant increase in Alanine excretion which is probably due to a lack in its metabolismo The excretion of branched chain aminoacids is increased in low-birth-weight infants according t6 the mo ment of birth. This points out towards a normalization of muscle metabolism in thcse infants. BCA index, is decreased at 15 days after birth in low-birth-weight infants respecting to the preterm infants, what shows the malnourished state of the former, but is favorably recovered after the first month in both cases. The same recovery is observed in the Gly/Val index

Published
1986

2. [Free amino acid content of human milk in Spain].

Author

Faus O, López Morales J, Faus MJ, Periago JL, Bueno Sánchez A, Gil A, and Martínez Valverde A

Subjects
Chromatography, High Pressure Liquid, Chromatography, Ion Exchange, Colostrum analysis, Female, Fluorometry, Humans, Lactation, Pregnancy, Amino Acids analysis, Milk, Human analysis
Abstract

The concentrations of free amino-acids have been determined in 54 samples of human milk: 18 in colostrum, 18 in transition milk and 18 in mature milk, all of them taken from women in the Eastern part of Andalucía. The amino-acids have been determined through high pressure ion-exchange chromatography and fluorimetric detection. Glutamic acid is the major free amino-acid, representing 21-52% of the total amount of these components in human milk. Its level increase significantly with advancing lactation. Taurine represents 14-19 of total free amino-acids in human milk, remaining its levels practically unchanged during the whole lactation. The fact that the major content of essential free amino-acids in present in human colostrum could suppose a contribution of these substances which are directly absorbable during a period of life when the nutritional requirements of the neonate are incremented.

Published
1984

3. [Free amino acids of various lacteal formulas used in Spain].

Author

Periago JL, Faus O, Martínez Valverde A, Bueno Sánchez A, Faus MJ, and Gil A

Subjects
Animals, Cattle, Humans, Infant Food analysis, Amino Acids analysis, Milk analysis, Milk, Human analysis
Abstract

A comparative study has been made upon free amino-acids in human milk, cow's milk and some infant formulas commercialized in Spain. The contents of free amino-acids in human milk is significantly increased when compared to those of raw of UHT sterilized cow's milk and to those of infant formulas. The concentrations of alanine are significantly lower in cow's milk and in infant formulas compared to human milk. The same occurs with branched chain amino-acids, glutamic acid, serine, threonine and taurine. On the contrary, the levels of free cysteine are significantly higher in cow's milk and in infant formulas. The concentrations of free amino-acids determined in different infant formulas on sale in Spain are rather similar between each others, being the cuantitative pattern very different from that determined in human milk.

Published
1984

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