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182 results on '"Faucher, D."'

1. Considérations pour l’interprétation et la comparaison de l’efficacité à long terme des études portant sur le traitement du psoriasis modéré à sévère à l’aide d’agents biologiques

Author

Langley, R.G., Egeberg, A., Gooderham, M., Bissonnette, R., Ringuet, J., Kalia, S., Park-Wyllie, L., Abbarin, N., Tran, D., Zara, A., Yang, W., Faucher, D., and Strober, B.

Abstract

Les comparaisons de l’efficacité à long terme des agents biologiques entre les différents essais cliniques pour le psoriasis en plaques (PSO) modéré à sévère sont hasardeuses de par la variabilité des designs et des méthodologies d’analyses utilisées.

Published
2024
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6. [3H](azidophenyl)ureido taxoid photolabels peptide amino acids 281-304 of alpha-tubulin

Author

Combeau, C., Loeb, C., Ehret-Sabatier, L., Bretin-Gilet, A., Faucher, D., Rousseau, B., Commercon, A., and Goeldher, M.

Subjects
Tubulins -- Analysis, Microtubules -- Analysis, Taxol -- Analysis, Biological sciences, Chemistry
Abstract

The binding site of taxoids on microtubules was analyzed by photoaffinity labeling utilizing the p-(azidophenyl)ureido derivative, TaxAPU, which exhibited modified side chains. The labeling of purified tubulin with TaxAPU occurred on the tryptic fragment of amino acids 281-304 of alpha-tubulin. Furthermore, the beta-tubulin fragment also exhibited a significant role in the taxoid recognition of the binding site on the microtubules.

Published
1997

7. Solution structure or RP 71955, a new 21 amino acid tricyclic peptide active against HIV-1 virus

Author

Frechet, D., Guitton, J.D., Herman, F., Faucher, D., Helynck, G., Sorbier, B. Monegier du, Ridoux, J.P., James-Surcouf, E., and Vuilhorgne, M.

Subjects
Peptides -- Research, Molecular dynamics -- Observations, Spectrum analysis -- Usage, Biological sciences, Chemistry
Abstract

Spectroscopic studies reveal that the 21 amino acid, tricyclic, HIV-antigenic peptide RP 71955 has a CLGIGSCNDFAGCGYAVVCFW solution sequence. Molecular dynamics and application of distance geometry and NOE back calculation reveal sequence similarities between RP 71955's three dimensional structure and the HIV-1 transmembrane protein gp41. RP 71955 contains an intrinsic amide bond between C1's NH2 molecule and D9's gamma-COOH motif.

Published
1994

10. Comparing very low birth weight versus very low gestation cohort methods for outcome analysis of high risk preterm infants.

Author

Austin N., Andersen C., Darlow B., Broadbent R., Corban J., Mildenhall L., Battin M., Bourchier D., Richardson V., Haslam R., Rajadurai V.S., Kajetanowicz A., Synnes A., Rouvinez-Bouali N., Piedboeuf B., Bertelle V., Bulleid B., Yee W., Shivananda S., Lee K.-S., Seshia M., Barrington K., Lefebvre F., McMillan D., Andrews W., Kovacs L., Dow K., da Silva O., Riley P., Peliowski A., Aziz K., Cieslak Z., Kalapesi Z., Sankaran K., Faucher D., Alvaro R., Canning R., Ojah C., Monterrosa L., Dunn M., Sorokan T., Harrison A., Nwaesei C., Adie M., Hakansson S., Segerdahl N., Morad T., Moren S., Stenberg A., Simonsson C., Stigsson L., Christensen J.L., Amasn L., Ingemanson F., osterdal L., Ellstrom K.-G., Abrahamsson T., Heimdahl I., Hagg T., Hedlund A., Lund E.E., Westrup B., Sarman I., Jobe A.S., Fredsriksson M., Palm A., Malmstrom B., Lindberg E., Ljungdahl O., Eriksson K., Koller-Smith L.I.M., Shah P., Ye X.Y., Sjors G., Wang Y.A., Chow S.S.W., Darlow B.A., Lee S.K., Hakanson S., Lui K., Marshall P., Craven P., Simmer K., Stack J., Knight D., Watkins A., Ramsden A., Tan K., Bawden K., Downe L., Singde V., Stewart M., Berry A., Hunt R., Kilburn C., Dargaville P., Paradisis M., Evans N., Reid S., Cartwright D., Kuschel C., Doyle L., Numa A., Kecskes Z., Badawi N., Koh G., Resnick S., Tracy M., Tarnow-Mordi W., Austin N., Andersen C., Darlow B., Broadbent R., Corban J., Mildenhall L., Battin M., Bourchier D., Richardson V., Haslam R., Rajadurai V.S., Kajetanowicz A., Synnes A., Rouvinez-Bouali N., Piedboeuf B., Bertelle V., Bulleid B., Yee W., Shivananda S., Lee K.-S., Seshia M., Barrington K., Lefebvre F., McMillan D., Andrews W., Kovacs L., Dow K., da Silva O., Riley P., Peliowski A., Aziz K., Cieslak Z., Kalapesi Z., Sankaran K., Faucher D., Alvaro R., Canning R., Ojah C., Monterrosa L., Dunn M., Sorokan T., Harrison A., Nwaesei C., Adie M., Hakansson S., Segerdahl N., Morad T., Moren S., Stenberg A., Simonsson C., Stigsson L., Christensen J.L., Amasn L., Ingemanson F., osterdal L., Ellstrom K.-G., Abrahamsson T., Heimdahl I., Hagg T., Hedlund A., Lund E.E., Westrup B., Sarman I., Jobe A.S., Fredsriksson M., Palm A., Malmstrom B., Lindberg E., Ljungdahl O., Eriksson K., Koller-Smith L.I.M., Shah P., Ye X.Y., Sjors G., Wang Y.A., Chow S.S.W., Darlow B.A., Lee S.K., Hakanson S., Lui K., Marshall P., Craven P., Simmer K., Stack J., Knight D., Watkins A., Ramsden A., Tan K., Bawden K., Downe L., Singde V., Stewart M., Berry A., Hunt R., Kilburn C., Dargaville P., Paradisis M., Evans N., Reid S., Cartwright D., Kuschel C., Doyle L., Numa A., Kecskes Z., Badawi N., Koh G., Resnick S., Tracy M., and Tarnow-Mordi W.

Abstract

Background: Compared to very low gestational age (<32 weeks, VLGA) cohorts, very low birth weight (<1500 g; VLBW) cohorts are more prone to selection bias toward small-for-gestational age (SGA) infants, which may impact upon the validity of data for benchmarking purposes. Method(s): Data from all VLGA or VLBW infants admitted in the 3 Networks between 2008 and 2011 were used. Two-thirds of each network cohort was randomly selected to develop prediction models for mortality and composite adverse outcome (CAO: mortality or cerebral injuries, chronic lung disease, severe retinopathy or necrotizing enterocolitis) and the remaining for internal validation. Areas under the ROC curves (AUC) of the models were compared. Result(s): VLBW cohort (24,335 infants) had twice more SGA infants (20.4% vs. 9.3%) than the VLGA cohort (29,180 infants) and had a higher rate of CAO (36.5% vs. 32.6%). The two models had equal prediction power for mortality and CAO (AUC 0.83), and similarly for all other cross-cohort validations (AUC 0.81-0.85). Neither model performed well for the extremes of birth weight for gestation (<1500 g and >=32 weeks, AUC 0.50-0.65; >=1500 g and <32 weeks, AUC 0.60-0.62). Conclusion(s): There was no difference in prediction power for adverse outcome between cohorting VLGA or VLBW despite substantial bias in SGA population. Either cohorting practises are suitable for international benchmarking.Copyright © 2017 The Author(s).

Published
2017

11. Comparing very low birth weight versus very low gestation cohort methods for outcome analysis of high risk preterm infants

Author

Koller-Smith, LIM, Shah, PS, Ye, XY, Sjörs, G, Wang, YA, Chow, SSW, Darlow, BA, Lee, SK, Håkanson, S, Lui, K, Marshall, P, Craven, P, Simmer, K, Stack, J, Knight, D, Watkins, A, Ramsden, A, Tan, K, Bawden, K, Downe, L, Singde, V, Stewart, M, Berry, A, Hunt, R, Kilburn, C, Dargaville, P, Paradisis, M, Evans, N, Reid, S, Cartwright, D, Kuschel, C, Doyle, L, Numa, A, Kecskes, Z, Badawi, N, Koh, G, Resnick, S, Tracy, M, Tarnow-Mordi, W, Andersen, C, Austin, N, Darlow, B, Broadbent, R, Corban, J, Mildenhall, L, Battin, M, Bourchier, D, Richardson, V, Haslam, R, Rajadurai, VS, Kajetanowicz, A, Synnes, A, Rouvinez-Bouali, N, Piedboeuf, B, Bertelle, V, Bulleid, B, Yee, W, Shivananda, S, Lee, KS, Seshia, M, Barrington, K, Lefebvre, F, McMillan, D, Andrews, W, Kovacs, L, Dow, K, da Silva, O, Riley, P, Peliowski, A, Aziz, K, Cieslak, Z, Kalapesi, Z, Sankaran, K, Faucher, D, Alvaro, R, Canning, R, Ojah, C, Monterrosa, L, Dunn, M, Sorokan, T, Harrison, A, Nwaesei, C, Adie, M, Håkansson, S, Segerdahl, N, Morad, T, Morén, S, Stenberg, Å, Simonsson, C, Stigsson, L, Christensen, JL, Åmasn, L, Ingemanson, F, österdal, L, Ellström, KG, Abrahamsson, T, Heimdahl, I, Hägg, T, Hedlund, A, Lund, EE, Koller-Smith, LIM, Shah, PS, Ye, XY, Sjörs, G, Wang, YA, Chow, SSW, Darlow, BA, Lee, SK, Håkanson, S, Lui, K, Marshall, P, Craven, P, Simmer, K, Stack, J, Knight, D, Watkins, A, Ramsden, A, Tan, K, Bawden, K, Downe, L, Singde, V, Stewart, M, Berry, A, Hunt, R, Kilburn, C, Dargaville, P, Paradisis, M, Evans, N, Reid, S, Cartwright, D, Kuschel, C, Doyle, L, Numa, A, Kecskes, Z, Badawi, N, Koh, G, Resnick, S, Tracy, M, Tarnow-Mordi, W, Andersen, C, Austin, N, Darlow, B, Broadbent, R, Corban, J, Mildenhall, L, Battin, M, Bourchier, D, Richardson, V, Haslam, R, Rajadurai, VS, Kajetanowicz, A, Synnes, A, Rouvinez-Bouali, N, Piedboeuf, B, Bertelle, V, Bulleid, B, Yee, W, Shivananda, S, Lee, KS, Seshia, M, Barrington, K, Lefebvre, F, McMillan, D, Andrews, W, Kovacs, L, Dow, K, da Silva, O, Riley, P, Peliowski, A, Aziz, K, Cieslak, Z, Kalapesi, Z, Sankaran, K, Faucher, D, Alvaro, R, Canning, R, Ojah, C, Monterrosa, L, Dunn, M, Sorokan, T, Harrison, A, Nwaesei, C, Adie, M, Håkansson, S, Segerdahl, N, Morad, T, Morén, S, Stenberg, Å, Simonsson, C, Stigsson, L, Christensen, JL, Åmasn, L, Ingemanson, F, österdal, L, Ellström, KG, Abrahamsson, T, Heimdahl, I, Hägg, T, Hedlund, A, and Lund, EE

Abstract

© 2017 The Author(s). Background: Compared to very low gestational age (<32 weeks, VLGA) cohorts, very low birth weight (<1500 g; VLBW) cohorts are more prone to selection bias toward small-for-gestational age (SGA) infants, which may impact upon the validity of data for benchmarking purposes. Method: Data from all VLGA or VLBW infants admitted in the 3 Networks between 2008 and 2011 were used. Two-thirds of each network cohort was randomly selected to develop prediction models for mortality and composite adverse outcome (CAO: mortality or cerebral injuries, chronic lung disease, severe retinopathy or necrotizing enterocolitis) and the remaining for internal validation. Areas under the ROC curves (AUC) of the models were compared. Results: VLBW cohort (24,335 infants) had twice more SGA infants (20.4% vs. 9.3%) than the VLGA cohort (29,180 infants) and had a higher rate of CAO (36.5% vs. 32.6%). The two models had equal prediction power for mortality and CAO (AUC 0.83), and similarly for all other cross-cohort validations (AUC 0.81-0.85). Neither model performed well for the extremes of birth weight for gestation (<1500 g and ≥32 weeks, AUC 0.50-0.65; ≥1500 g and <32 weeks, AUC 0.60-0.62). Conclusion: There was no difference in prediction power for adverse outcome between cohorting VLGA or VLBW despite substantial bias in SGA population. Either cohorting practises are suitable for international benchmarking.

Published
2017

17. CHRONIQUE GÉOGRAPHIQUE

Author

Deffontaines, P., Faucher, D., Vergez-Tricom, G., Allix, Juliette, and Célérier, J.

Published
1923

19. CHRONIQUE GÉOGRAPHIQUE

Author

Maurain, Ch., Gallois, L., Faucher, D., d'Almeida, P. Camena, Musset, R., Arbos, Ph., and Deffontaines, P.

Published
1924

22. Avertissement

Author

Duby, G. and Faucher, D.

Published
1961

28. Optically Phase-locked Lasers for RF Photonics Applications

Author

Poulin, M., primary, Ayotte, S., additional, Costin, F., additional, Babin, A., additional, Faucher, D., additional, Aubé, M., additional, Latrasse, C., additional, Savard, S., additional, Robidoux, G., additional, Laliberté, M., additional, and Pelletier, F., additional

Published
2015
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29. Microbial degradation of RDX and HMX in marine sediments

Author

Monteil-Rivera, F., Zhao, J., Faucher, D., Greer, C. W., Ampleman, G., Thiboutot, S., and Hawari, J.

Subjects
Water, environmental
Abstract

The 14th AEHS Annual West Coast Conference on Soils, Sediments, and Water, March 15-18, 2004 San Diego, CA, USA

Published
2009

32. Avertissement

Author

Duby, G. and Faucher, D.

Published
2003

33. Environmental Assessment of Small Arms Live Firing: Study of Gaseous and Particulate Residues

Author

DEFENCE RESEARCH AND DEVELOPMENT CANADA VALCARTIER (QUEBEC), Brochu, S, Poulin, I, Faucher, D, Diaz, E, Walsh, M R, DEFENCE RESEARCH AND DEVELOPMENT CANADA VALCARTIER (QUEBEC), Brochu, S, Poulin, I, Faucher, D, Diaz, E, and Walsh, M R

Abstract

Small arms training is an important military activity of the Canadian Forces and the U.S. Army, and contributes to the accumulation of residues on the training areas. In the present work, the amount of unburned energetic residues deposited per round was estimated for five calibers (9 mm, 7.62 mm, 5.56 mm, 0.50 and 0.338) and nine weapons (Browning and Sig Sauer pistols, rifle C7, carabine C8, machine guns C6, C9 and M2HB, and rifles McMillan and Timberwolf).

Published
2011

35. Environmental Conditions of Surface Soils and Biomass Prevailing in the Training Area at CFB Gagetown, New Brunswick

Author

COLD REGIONS RESEARCH AND ENGINEERING LAB HANOVER NH, Thiboutot, S, Ampleman, G, Lewis, J, Faucher, D, Marois, A, Martel, R, Ballard, J M, Downe, S, Jenkins, T, Hewitt, A, COLD REGIONS RESEARCH AND ENGINEERING LAB HANOVER NH, Thiboutot, S, Ampleman, G, Lewis, J, Faucher, D, Marois, A, Martel, R, Ballard, J M, Downe, S, Jenkins, T, and Hewitt, A

Abstract

Troop readiness requires live fire training with various types of ammunitions. More than 99.99 % of the Canadian ammunition stockpile is used in our Country in training exercises. By better understanding the potential environmental impacts of each type of live firing activity, the Department of National Defence (DND) will be able to mitigate potential adverse effects by adapting the practices to minimize such adverse impacts. In this context, the Director Land Environment (OLE) tasked DRDC-Val to initiate a R&D program invoMng the environmental characterization of their main training areas to improve the knowledge on the impacts of many types of live firing training activities. DRDC-Valcartler managed the overall work and performed the surface soils and biomass studies in collaboration with Cold Regions Research and Engineering Laboratory (CRREL) scientists. The second site selected for the study was CFB Gagetown based on its intensive use by our force and allied forces and based on its geological and geographical context. In 2001, hydrogeological work was conducted in the northern half of the CFB Gagetown. This first phase involved the sampling of 42 wells to characterize the underlying groundwater flow dynamics as well as the chemical characterization of the groundwater quality. In 2002, a second phase was undertaken, including the drilling of more wells mostly in the southern half of the base and the collection of surface soils and biomass at selected locations over the entire base. This report details the surface soils and biomass characterisation of Gagetown main training ranges while a second report will be published on the hydrogeological context of the training area. Both energetic materials and metals were analysed in surface soil samples while only metals were analysed in the biomass samples. Various types of ranges were sampled including, antiarmour, antitank, grenade and rifle ranges as well as artillery Impact areas., Prepared in collaboration with INRS-Eau, Terre et Environnement and CFB Gagetown.

Published
2003

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