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Kaliteli eğitimin bir bileşeni olarak etkili öğretim geleneksel eğitim anlayışında öğrencilerin sınav başarısı ile birebir eşlenirken günümüzde etkili öğretim uygulamaları çok daha kapsamlı olarak ele alınmaktadır. Eğitim-öğretim süreçlerindeki bu yenilikçi bakış açısı doğrultusunda öğretmenlerin öğretim pratiklerinde de yenilikler ve gelişimler söz konusudur. Öğretmenlerin mevcut öğretim uygulamalarında değişiklikler ve yeni uygulamalara uyum sağlaması noktasında mesleki gelişime ihtiyaç duydukları açıktır ve bu ihtiyaç pek çok disiplin alanı için geçerli olduğu gibi matematik öğretmenleri için de geçerlidir. Bu çalışmada matematik öğretmenlerinin mesleki gelişimlerine yönelik bir model matematik koçluğu ele alınmıştır. Çalışmada uluslararası alan yazında büyük ölçekte koçluk, özelde ise matematik koçluğu ile ilgili çalışmalardan elde edilen bulgular ile koçluğun ne olduğu ve neden ihtiyaç duyulduğu, koçluk türleri, koçluk sürecindeki temel unsurlar, koçluk süreci ve uygulanma şekli, etkili koçluk süreci için destekleyici mekanizmalar, sürecin zorlukları ele alınmıştır. Bu bilgiler ışığında Türkiye’de matematik koçluğu sürecinde kullanılabilecek okul temelli bir mesleki gelişim modeli olarak yansıtıcı matematik koçluğu modeli önerisi geliştirilmiştir.

In this study, the mathematical modeling process of in-service middle school mathematics teachers who participated in a mathematical modeling workshop within the scope of a professional development program were examined. This study is a multi-case study with the participation of six teachers (two women; four men) and investigates how teachers handled the theoretical knowledge gained during the mathematical modeling workshop in the problem designing process. The data consists of problems designed by teachers and individual interviews. The findings show that teachers were generally successful in transferring their theoretical knowledge to the problem designing process, but had some difficulties. Besides, it can be said that they overcame these difficulties in the process and obtained the problem designing competence that is suitable for the mathematical modeling criteria. The results show that implementation has an important role in the development of a modeling point of view just like theory and that the balance of theory and application should be established in modeling education.

© 2022, King Abdulaziz City for Science and Technology.Organic@inorganic hybrid nanoflowers (hNFs), which are widely used in enzyme purification and catalytic activity applications, include both organic and inorganic components. In this study, hNFs were synthesized with the combination of Ascoseira mirabilis extract and Cu in phosphate-buffered saline (PBS) while altering the concentration and medium pH instead of using expensive molecules that are difficult to obtain such as enzymes or DNA. According to the obtained FE-SEM images, the morphology of the hNFs was related to the pH of the PBS (synthesis did not occur at pH 5) and the volume of the extract. The presence of Cu and other components was detailed with EDX mapping. The presence of functional groups playing key roles in the synthesis process was evaluated based on FT-IR peaks. The Cu hNFs exhibited peroxidase-like catalytic activity against guaiacol and demonstrated antimicrobial and antioxidant activities. This study is original and innovative in terms of using an Ascoseira mirabilis extract for hNF synthesis and evaluating the antioxidant, catalytic, and antimicrobial activities of Ascoseira mirabilis-based hNFs. The research sheds light on hNF synthesis and the possibility of biological activity application studies performed with bioextracts instead of biomolecules obtained via expensive and complex processes.

Recently, it has been known that carbon fiber, a conductive fiber, is used in different mixture designs and the development of electrically conductive cementitious materials. However, the evaluation of ferrochrome slag as a recycled aggregate in the mixture of these special concretes has still not been investigated. In this study, electrically conductive mortars were produced using 100% recycled ferrochrome slag aggregate with a particle size of less than 1 mm as filling material and using carbon fiber in 4 different ratios, 0%, 0.5%, 0.75%, and 1%. To investigate the electrical conductivity properties, the resistivity values of the samples were measured at five different times within 2–180 days. In addition, 28-day compressive strength, flexural strength, dynamic resonance, ultrasonic pulse velocity, Leeb hardness, scanning electron microscope, and X-Ray Diffraction tests were performed on all samples. The results were compared with the literature, proving that ferrochrome slag could be used as a reasonable aggregate in conductive mortars. The age effect was minimal in CF-added mixtures. With the addition of 1% CF, the resistivity values decreased approximately 40 times compared to the reference. Moreover, SEM analyses of the CF-0.75 sample showed that the CFs adhered to form a conductive network between the components in the ferrochrome-filled compact structure.

Bu çalışmanın amacı örgütsel iletişimin örgütsel sessizlik üzerindeki etkisini saptamak ve bu iki değişken arasındaki ilişkide psikolojik rahatlığın aracı rolünün olup olmadığını belirlemektir. Bu amaç doğrultusunda belirlenen araştırma hipotezleri, özel bir banka çalışanlarından oluşan 351 kişilik örneklem grubundan anket yöntemiyle toplanan verilerle test edilmiştir. Çalışma, “örgüt” bağlamı içerisinde önemli bir konumda olan örgütsel iletişimdeki sessizlik türlerinin, örgüt içindeki çalışanlarda psikolojik rahatlık ile bağlantılı olarak ortaya çıkan sonuçlarını bilimsel yöntemler ile sunmaktır. Araştırma sonucunda Örgütsel iletişim ile psikolojik rahatlık arasında pozitif yönlü, örgütsel iletişim ile örgütsel sessizlik arasında negatif yönlü ve örgütsel sessizlik ile psikolojik rahatlık arasında da negatif yönlü istatistiksel olarak anlamlı ilişkiler olduğu görülmüştür. Ayrıca örgütsel iletişimin örgütsel sessizlik üzerindeki etkisinde analize psikolojik rahatlığın da eklenmesiyle bir azalma gözlemlendiğinden, örgütsel iletişimin örgütsel sessizlik üzerindeki etkisinde psikolojik rahatlığın aracılık etkisinin olduğu görülmüştür. Bu sonuca göre kurum içerisinde iletişimin güçlendirilmesiyle psikolojik rahatlığın artacağı ve çalışanların verimliliğini düşüren sessiz kalma eğilimlerinin azalacağı söylenebilir. Böylelikle çalışanlar tarafından geri bildirimler artacak, bireysel / örgütsel / sistemsel gelişimine katkı sunacak fikir ve önerilerini rahatlıkla dile getirebilecekler ve örgütün hedeflerine ulaşmasına katkı sağlayabileceklerdir.

The trace element selenium is crucial for cellular defense against oxidative stress and inflammatory reactions. Balanced selenium levels are important for the vascular system, whereas dysregulation can damage vascular reactivity. Reports have also supported the strong relationship between oxidative stress and vascular inflammation, which are induced by either the overproduction of reactive oxygen species (ROS) or the lack of antioxidant defense proteins. The damage of vascular smooth muscle and endothelium layer are frequently linked to vascular disorders such as hypertension, hypercholesterolemia, and atherosclerosis. Vascular diseases can result in life-threatening serious cardiovascular complications, such as blood clots, heart attack, and stroke. Selenium levels are crucial for preventing vascular damage; however, either low or extremely high amounts of selenium intake may contribute to the pathophysiology of vascular disorders. Selenoproteins are proteins such as glutathione peroxidase containing selenium in the form of the 21st amino acid, selenocysteine. Selenoproteins have the capacity to protect vascular smooth muscle and endothelium by lowering harmful ROS, which allows them to regulate normal vascular functions including vasoreactivity. The current chapter’s goal was to carry out a thorough evaluation of the literature on the connection between selenium and vascular disorders.

Artan göç dalgalarıyla birlikte Türkiye’deki okulların kültürel ve etnik yapısı gün geçtikçe daha çeşitli hale gelmiş ve adil matematik öğrenme fırsatlarına odaklanma gerekliliği ortaya çıkmıştır. Bu çalışmanın amacı sınıf öğretmenlerinin ve ortaokul matematik öğretmenlerinin kültürel çeşitlilik gösteren öğrencilerin matematik öğrenme fırsatlarına yönelik bakış açılarını araştırmak ve matematiği erişilebilir kılmak için belirledikleri pedagojik stratejileri ortaya çıkarmaktır. Bu doğrultuda nitel bir anket formu hazırlanarak 83 öğretmene ulaşılmıştır. Yapılan analizlerin sonucunda, çalışmaya katılan öğretmenler kültürel çeşitlilik gösteren öğrencilerin matematik derslerine katılımının daha az ve matematik öğretirken en zorlanılan konunun ise dil farklılıkları ve sınıf içi iletişim problemi olduğunu ifade ederken farklı kültürlere sahip öğrencilerinden temel matematik bilgi ve becerileri öğrenmesini beklemektedirler. Kültürel olarak çeşitli olan sınıflarda matematiğe adil erişim için kullanılan pedagojik stratejiler arasında temel olarak görsel materyal ve resimlerin kullanma, seviyelerine göre farklılaştırma ve günlük yaşantılarından örnekler verme sayılabilir. Ancak katılımcıların dörtte biri matematik öğrenmek için Türkçe dilinin öğrenilmesi gerektiğini savunmuşlardır. Bulgular ışığında, kültürel ve dilsel olarak duyarlı matematik pedagojilerinin çok kültürlü sınıflarda görev yapan öğretmenler ile mesleki gelişim projeleriyle paylaşılması ve uygulamaya koyulması önerilebilir. Ayrıca matematik öğrenme fırsatlarını derinlemesine inceleyen nitel çalışmalara ihtiyaç vardır.

© 2022 Taylor & Francis Group, LLC.First time in this study, neuroprotective or neurotoxic effects of Pseudevernia furfuracea and Usnea florida lichen extracts based silver decorated zinc oxide nanocomposites (Ag-ZnO NCs) were evaluated. The characteristic light absorption point of P. furfuracea and U. florida based Ag-ZnO NCs were observed at 339 nm and 361 nm; effective diameter was detected at 342 nm and 495 nm. According to SEM analysis, the diameter of P. furfuracea and U. florida extract based NCs were approximately 35 nm and 85 nm, respectively. When we examined the toxicity of SH-SY5Y against human neuroblastoma cells, it was observed that NCs have neurotoxic effects on a concentration of 100 μg/ml. In this study, it was predicted that P. furfuracea and U. florida extract based Ag-ZnO NCs could be used in cytotoxic studies by synthesizing them in a cheap, short time and with eco-friendly method.

Objective: We aimed to evaluate if the Mean Platelet Volume (MPV) is an acute phase reactant in non-healing wounds, by analyzing its correlation with Erythrocyte Sedimentation Rate (ESR). Method: Our study was carried out in a descriptive type with the participation of patients with non-healing wounds. The laboratory data and characteristics of the patients were accessed retrospectively, and the obtained data were recorded in the data recording form. Results: The sample group consisted of 92 patients with non-healing wounds. 26.9% of the patients with non-healing wounds had pressure sores, 37.6% of them had diabetic foot wounds, 18.3% had non-healing wounds developed after trauma, and 17.2% had necrotizing fasciitis. The average age of the patients was 53.22±19.13, and the average length of stay in the hospital was 108.98±18.78 (min 3 months, max 6 months) days. The MPV value, which was found to be high in the early stages of non-healing wounds, decreased after the wound was completely healed. When the MPV value was compared to ESR, an acute phase reactant, a positive and strong statistically significant correlation was found between MPV and ESR based on the result of this correlation analysis (r=0.256, p

Background/aim: Hydroxychloroquine (HCQ) is an antimalarial that is widely used in the management of rheumatoid arthritis and other autoimmune diseases. In this study, we aimed to examine the vascular effects of HCQ on rat aorta (RA). Materials and methods: The RA rings were suspended in isolated organ baths and tension was recorded isometrically. HCQ-induced relaxations were tested in the presence of the nitric oxide synthase inhibitor, nitro-L-arginine methyl ester (L-NAME, 100 mM); the cyclooxygenase enzyme inhibitor, indomethacin (10 mM); the calcium (Ca2+) ion channel blocker, nilvadipine (10 ?M); and the K+ ion channel inhibitors, tetraethylammonium (1 mM), glibenclamide (10 mM), 4-aminopyridine (1 mM), and barium chloride (30 mM). The effect of HCQ on Ca2+ channels was examined using Ca2+-free Krebs solution, and adding calcium chloride (CaCl2, 10-5– 10-2 M) cumulatively to baths incubated with HCQ. Results: Removing the endothelium resulted in less relaxation of RA rings compared to endothelium-intact rings (p < 0.05). The effect of endothelium was supported by using L-NAME where HCQ produced-vasorelaxation was decreased (p < 0.05). The contraction of vascular rings was inhibited to a significant degree following the addition of CaCl2, PE, or KCl on HCQ-incubated RA rings (p < 0.05). The incubation of the RA rings with the Ca2+ channel blocker, the K+ channel blockers, and the COX inhibitor, indomethacin did not significantly affect vascular relaxation induced by HCQ. Conclusion: HCQ produced relaxation of RA rings. The relaxation mechanism differs according to the concentration of HCQ. At concentrations of 10-6 and 10-5 M, the relaxation is endothelium-dependent and mediated by NO. We strongly suggest that Ca2+ channel inhibition is involved at concentrations of 10-5 and 10-4 M, as well as NO. © TÜBİTAK.

Background: Favipiravir (FPV), an effective antiviral agent, is a drug used to treat influenza and COVID-19 by inhibiting the RNA-dependent RNA polymerase (RdRp) of RNA viruses. FPV has the potential to increase oxidative stress and organ damage. The purpose of this study was to demonstrate the oxidative stress and inflammation caused by FPV in the liver and kidneys of rats, as well as to investigate the curative effects of vitamin C (VitC).Methods: A total of 40 Sprague-Dawley male rats were randomly and equally divided into the following five groups: 1st; Control, 2nd; FPV = 20 mg/kg, 3rd; FPV = 100 mg/kg, 4th; FPV = 20 mg/kg + VitC (150 mg/kg), and 5th; FPV = 100 mg/kg + VitC (150 mg/kg) groups. Rats were given either FPV (orally) or FPV plus VitC (intramuscular) for 14 days. Rat blood, liver, and kidney samples were collected at 15 days to be analyzed for oxidative and histological changes.Results: FPV administration resulted in an increase in proinflammatory cytokines (TNF-alpha and IL-6) in the liver and kidney, as well as oxidative and histopathologic damage. FPV increased TBARS levels significantly (p < .05) and decreased GSH and CAT levels in liver and kidney tissues but had no effect on SOD activity. VitC supplementation significantly reduced TNF-a, IL-6, and TBARS levels while increasing GSH and CAT levels (p < .05). Furthermore, VitC significantly attenuated FPV-induced histopathological alterations associated with oxidative stress and inflammation in the liver and kidney tissues (p < .05).Conclusion: FPV caused liver and kidney damage in rats. In contrast, co-administration of FPV with VitC improved FPV-induced oxidative, pro-inflammatory, and histopathological changes.

Objective: The aim of the study was to investigate the preventive effects of Taurine against 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD)-induced organ damage in rats. The environmental toxin TCDD has a high toxicity in animal and human tissues. Taurine is an amino acid found in organ cells that has and antioxidant properties and anti-inflammatory. As a result, the potential preventive effect of taurine on oxidative stress and organ damage caused by TCDD was investigated in rat liver and kidney tissues by measuring glutathione (GSH), superoxide dismutase (SOD) activity, and thiobarbituric acid reactive substances (TBARS) levels. Material and Method: Adult male Wistar rats (250-300 g, 12-13 weeks, n = 32) were randomly allocted into four groups (n = 8/group): Control, TCDD, TAU, and TCDD+TAU. TCDD and/or taurine were administered via gavage in doses of 2 μg/kg/week and 200 mg/kg/day, respectively. Result and Discussion: The results showed that TCDD caused oxidative stress in the liver and kidney tissues of rats by decreasing the levels of GSH and SOD activity and increasing the levels of TBARS. Taurine treatment significantly reduced TBARS levels (p

Bu çalışma 12-14 yaş grubu tenisçilerin tenise özgü becerilerinin incelenmesi amacıyla yapılmıştır. Çalışmaya toplam 20 (Kadın: 10, Erkek: 10) gönüllü tenis sporcusu katılmıştır. Çalışmaya katılan tenisçilerin vücut kompozisyonun belirlenmesinde boy uzunluğu, vücut ağırlığı ve bazı kinantropometrik ölçümleri kullanılmıştır. Tenise özgü becerilerin belirlenmesinde ise Dewitt- Dugan ve Broer-Miller testi kullanılmıştır. İzometrik kuvvetin belirlenmesinde pençe, bacak, sırt ve toplam kuvvet kullanılmıştır. Anaerobik performans belirlenmesi ise dikey sıçrama testi ile kullanılmıştır. Tenise özgü beceriler ile vücut kompozisyonu, kuvvet, anaerobik performans değerleri arasındaki ilişkilerin değerlendirilmesi amacıyla Pearson Product Moment Korelasyon Katsayısı yöntemi kullanılmıştır. Pearson Product Moment Korelasyon analizi sonuçlarına göre tenise özgü beceriler ile vücut kompozisyonu, kuvvet ve anaerobik performans değişkenleri arasında ilişki bulunmuştur. Sonuç olarak, çalışmada ki bulgular 12-14 yaş tenisçilerde vücut kompozisyonu, kuvvet ve anaerobik performans değişkenlerinin tenis özgü becerileri performanslarında belirleyici rol aldığını göstermiştir.

This research aims to determine the effectiveness of the erroneous solution method on learning the line graph, mean, median, and mode at 7th grade. This is a semi-experimental study model based on teaching the concepts of statistics with erroneous examples. The participants of the study were randomly selected 70 students studying in the 7th grade in the 2018-2019 academic year. Eight activities that involve erroneous examples were used during the data collection process and an achievement test was conducted as pre-test and post-test before and after classroom implementation. The obtained data were analyzed using the SPSS package program. In order to examine the effect of activities, a t-test was performed. The results of the analysis revealed that the erroneous solution method had a positive effect on learning the concepts of line graph, mean, median, and mode., Bu araştırmanın amacı, hata temelli aktivitelerin 7. Sınıf veri analizi alt öğrenme alanına ait çizgi grafiği, ortalama, medyan ve mod kavramlarını öğrenmeye etkisini belirlemektir. Araştırma hatalı örneklerle istatistik kavramlarının öğretilmesine dayalı yarı deneysel bir çalışma modelidir. Çalışmanın katılımcıları 2018-2019 öğretim yılında 7. sınıfta öğrenim gören rastgele seçilmiş 70 öğrenciden oluşmaktadır. Öğrenim sürecinde hatalı çözülmüş örnekler içeren sekiz çalışma kağıdı kullanılmış, başarı testi hazırlanarak ön- test ve son- test olarak uygulanmıştır. Elde edilen veriler SPSS paket programı kullanılarak analiz edilmiştir. Etkinliklerin etkisini incelemek amacıyla t-testi sonuçlarına yer verilmiştir. Analiz sonuçları, hata temelli aktivitelerin çizgi grafiği, ortalama, medyan ve mod kavramlarının öğrenilmesine olumlu etki yaptığını göstermiştir.

Marketplace waste collection is one of the crucial services provided by the district municipalities in Turkey. A significant amount of food waste is periodically collected from marketplaces. However, an important opportunity for recycling and mitigation climate change is missed because these waste are sent to landfills. Composting, one of the waste management technologies applied to organic waste to reduce greenhouse gas emissions and produce compost, is often preferred for the management of marketplace waste. This study aims to determine suitable locations for compost facilities to manage marketplace waste with the help of GIS considering economic, environmental, and topographic factors in Izmir, Turkey. There are 199 marketplaces in Izmir and each has at least one market a week. Each marketplace was weighted by means of population served by using location-allocation analysis since the amount of waste collected from the marketplaces is not known. First, an exclusion analysis was performed to remove limited use areas. Then, a preference analysis was performed. Factors affecting plant site selection process for composting marketplace waste, including marketplace locations and weights, were determined. Since all factors do not have equal importance, the analytical hierarchy process was used to determine weights for each factor based on their influence. The study area was spatially evaluated for each preference factor and a suitability map was created for each factor. Finally, a high-resolution final suitability map was obtained by combining each factor’s suitability map along with their weights. Areas with a suitability index greater than 80% have been defined as suitable areas for compost facility installation. The results indicate that there are 323 potential locations suitable for compost facilities in Izmir.

Recently, great efforts have been made by researchers on the mixture of electrically conductive concretes that have been developed for different purposes. In this study, an experimental research was carried out on electrically conductive mortar mixtures especially for shell elements produced for building facade cladding. Six different mixtures were produced, including the non-conductive reference mixture. Single-walled carbon nanotube (SWCNT) was used as nano-sized conductive additive material. SWCNT was added at 0.2% and 0.3% of cement weight. SF was added to the same mixtures as another group at the rate of 4% by total weight. 2, 14, 28, 90 and 180 days electrical resistivities of the obtained conductive mortar samples were measured. As a non-destructive method, dynamic resonance testing was performed and the 28-day damping rates of the samples were determined. Ultrasonic pulse velocity (UPV) and Leeb hardness tests were performed, respectively, by using other non-destructive testing methods to obtain information about the internal structure voids and surface hardness of the samples. SWCNT, which causes low machinability and therefore internal structure voids, caused a decrease in compressive strength and flexural strength, as well as a significant increase in electrical conductivity.

The teachers' pedagogical understanding of modeling applications is one of the most critical issues in teaching mathematical modeling. The interventions used by the teacher during the implementation of the tasks are the mirror of their pedagogical knowledge. For this reason, teacher interventions, which have a decisive effect on defining the teacher's role in teaching mathematical modeling, are a crucial issue to investigate. This study examines the types of interventions used by a middle school mathematics teacher who completed professional development in mathematical modeling. The data was collected in an eighth-grade classroom consisting of twenty students. The mathematical modeling task, called Intersection Arrangement, was implemented for 2 hours, and both video and audio recordings were used to collect data. All recordings were transcribed and analyzed using the content analysis method, supported by observer notes and student worksheets. The results revealed that the teacher mostly had effective environmental and classroom interaction interventions. The teacher avoided having content-oriented or strategic interventions or did not intervene during the modeling process. These intervention types might be because of the teacher's unwillingness to affect the modeling process. On the other hand, the fact that the teacher was more active in the presentation and evaluation stage supports his hesitations and difficulties about where and how to intervene in the modeling process. The relevant literature and the results of this research show that teachers must have unique pedagogical knowledge in teaching mathematical modeling.