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2 results on '"Fat mass to fat-free mass ratio"'

1. Body Composition in Cases with Normal Alanine Aminotransferase Values in Medical Health Checkups.

Author

Ushiro, Kosuke, Fukuda, Akira, Matsui, Masahiro, Onishi, Saori, Nishikawa, Tomohiro, Asai, Akira, Kim, Soo Ki, and Nishikawa, Hiroki

Abstract

Background and aims: We aimed to clarify the relationship between alanine aminotransferase (ALT) level and body composition in Japanese medical health checkups, especially in cases with ALT ≤ 30 IU/L (7569 men and 9497 women). Methods: We categorized our study cohort into four groups: type A (ALT value ≤ 10 IU/L), type B (11 ≤ ALT value ≤ 20 IU/L), type C (21 ≤ ALT value ≤ 30 IU/L) and type D (ALT value > 30 IU/L (ALT over 30)). We retrospectively compared body composition-related parameters (body mass index (BMI), waist circumference (WC), fat (F) index, fatty liver index (FLI), fat-free (FF) index and F-FF ratio) among the four types. Results: Type A/B/C/D in men and women was found in 262/3279/2107/1921 and 1549/5736/1495/717 (p < 0.0001). BMI, WC, F-index, FLI, FF index and F-FF ratio were all significantly stratified among the four types, regardless of whether they were male or female and over or under 50 years old. Conclusions: With a decrease in ALT level in medical health checkups, fat mass decreases, and F-FF ratio decreases, but a decrease in skeletal muscle mass cannot be overlooked. [ABSTRACT FROM AUTHOR]

Published
2024
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2. Fat mass to fat-free mass ratio and its associations with clinical characteristics in asthma

Author

Diery Fernandes Rugila, Joice Mara Oliveira, Felipe Vilaça Cavallari Machado, Natielly Soares Correia, Vitória Cavalheiro Puzzi, Natália Febrini Piassi Passos, Patrícia Duarte Freitas, Fabio Pitta, Celso Ricardo Fernandes Carvalho, Karina Couto Furlanetto, RS: NUTRIM - R3 - Respiratory & Age-related Health, and Pulmonologie

Subjects
Pulmonary and Respiratory Medicine, FFM, Fat-free mass, FFM, Physical Activity in Daily Life, GINA, Global Initiative for Asthma, BODY-FAT, ACQ Asthma Control Questionnaire, Fat mass to fat-free mass ratio, BMI, Body mass index, Critical Care and Intensive Care Medicine, Body composition, Motor activity, FEV1/FVC Forced expiratory volume in the first second to forced vital capacity ratio, VALIDATION, HADS, Hospital Anxiety and Depression Scale, FM/FFM, BMI, FEV1, FEV1, Forced expiratory volume in the first second, BIOELECTRICAL-IMPEDANCE ANALYSIS, FM, Forced vital capacity, Electric Impedance, Humans, Forced expiratory volume in the first second, FM/FFM, Fat mass to fat-free mass ratio, PEDOMETER, Body mass index, AQLQ Asthma Quality of Life Questionnaire, HADS, Fat mass, Respiratory function tests, FM, Fat mass, GINA, Asthma, FVC, Fat-free mass, Hospital Anxiety and Depression Scale, PADL, Physical Activity in Daily Life, PHYSICAL-ACTIVITY, FVC, Forced vital capacity, PADL, Quality of Life, Drug therapy, Cardiology and Cardiovascular Medicine, Global Initiative for Asthma
Abstract

BACKGROUND: Fat mass to fat-free mass ratio (FM/FFM) assesses the combined effect of the balance between fat mass and fat-free mass.AIMS: to evaluate the associations beetween FM/FFM and clinical outcomes in asthma and to compare clinical characteristics between individuals with higher and lower FM/FFM.METHODS: 128 participants with asthma underwent anthropometric, spirometry and bioelectrical impedance assessments. Physical activity in daily life (PADL) was assessed by the Actigraph for 7 days. Daily dose of inhaled medication, steps of pharmacological treatment, Asthma Control Questionnaire, Asthma Quality of Life Questionnaire and Hospital Anxiety and Depression Scale were also assessed. Participants were classified into two groups according to the 50th percentile of reference values for FM/FFM.RESULTS: Individuals with higher FM/FFM (n=75) used higher daily doses of inhaled corticosteroids, had worse lung function and fewer steps/day when compared to those with lower FM/FFM (n=53) (P≤0.021). Associations were found between absolute values of FM/FFM with lung function (FEV1 and FVC [liters]): R2=0.207 and 0.364;PCONCLUSION: Higher FM/FFM is significantly associated with worse clinical characteristics in individuals with asthma, such as higher doses of inhaled corticosteroids, worse lung function and fewer steps/day. Moreover, higher FM/FFM is a determining factor of physical inactivity and the highest steps of pharmacological treatment for asthma.

Published
2022

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