197 results on '"Fasanelli, Francesca"'
Search Results
2. Heterogeneity of Colorectal Cancer Risk Factors by Anatomical Subsite in 10 European Countries: A Multinational Cohort Study
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Murphy, Neil, Ward, Heather A., Jenab, Mazda, Rothwell, Joseph A., Boutron-Ruault, Marie-Christine, Carbonnel, Franck, Kvaskoff, Marina, Kaaks, Rudolf, Kühn, Tilman, Boeing, Heiner, Aleksandrova, Krasimira, Weiderpass, Elisabete, Skeie, Guri, Borch, Kristin Benjaminsen, Tjønneland, Anne, Kyrø, Cecilie, Overvad, Kim, Dahm, Christina C., Jakszyn, Paula, Sánchez, Maria-Jose, Gil, Leire, Huerta, José M., Barricarte, Aurelio, Quirós, J. Ramón, Khaw, Kay-Tee, Wareham, Nick, Bradbury, Kathryn E., Trichopoulou, Antonia, La Vecchia, Carlo, Karakatsani, Anna, Palli, Domenico, Grioni, Sara, Tumino, Rosario, Fasanelli, Francesca, Panico, Salvatore, Bueno-de-Mesquita, Bas, Peeters, Petra H., Gylling, Björn, Myte, Robin, Jirström, Karin, Berntsson, Jonna, Xue, Xiaonan, Riboli, Elio, Cross, Amanda J., and Gunter, Marc J.
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- 2019
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- View/download PDF
3. Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study
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Baumeister, Sebastian E., Schlesinger, Sabrina, Aleksandrova, Krasimira, Jochem, Carmen, Jenab, Mazda, Gunter, Marc J., Overvad, Kim, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, Carbonnel, Franck, Fournier, Agnès, Kühn, Tilman, Kaaks, Rudolf, Pischon, Tobias, Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, La Vecchia, Carlo, Masala, Giovanna, Panico, Salvatore, Fasanelli, Francesca, Tumino, Rosario, Grioni, Sara, Bueno de Mesquita, Bas, Vermeulen, Roel, May, Anne M., Borch, Kristin B., Oyeyemi, Sunday O., Ardanaz, Eva, Rodríguez-Barranco, Miguel, Dolores Chirlaque López, María, Felez-Nobrega, Mireia, Sonestedt, Emily, Ohlsson, Bodil, Hemmingsson, Oskar, Werner, Mårten, Perez-Cornago, Aurora, Ferrari, Pietro, Stepien, Magdalena, Freisling, Heinz, Tsilidis, Konstantinos K., Ward, Heather, Riboli, Elio, Weiderpass, Elisabete, and Leitzmann, Michael F.
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- 2019
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- View/download PDF
4. Methylation in host and viral genes as marker of aggressiveness in cervical lesions: Analysis in 543 unscreened women
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Fiano, Valentina, Trevisan, Morena, Fasanelli, Francesca, Grasso, Chiara, Marabese, Federica, da Graça Bicalho, Maria, de Carvalho, Newton S., Maestri, Carlos A., Merletti, Franco, Sacerdote, Carlotta, De Marco, Laura, and Gillio-Tos, Anna
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- 2018
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5. Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study
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Zamora-Ros, Raul, Alghamdi, Muath A., Cayssials, Valerie, Franceschi, Silvia, Almquist, Martin, Hennings, Joakim, Sandström, Maria, Tsilidis, Konstantinos K., Weiderpass, Elisabete, Boutron-Ruault, Marie-Christine, Hammer Bech, Bodil, Overvad, Kim, Tjønneland, Anne, Petersen, Kristina E. N., Mancini, Francesca Romana, Mahamat-Saleh, Yahya, Bonnet, Fabrice, Kühn, Tilman, Fortner, Renée T., Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, Martimianaki, Georgia, Masala, Giovanna, Grioni, Sara, Panico, Salvatore, Tumino, Rosario, Fasanelli, Francesca, Skeie, Guri, Braaten, Tonje, Lasheras, Cristina, Salamanca-Fernández, Elena, Amiano, Pilar, Chirlaque, Maria-Dolores, Barricarte, Aurelio, Manjer, Jonas, Wallström, Peter, Bueno-de-Mesquita, H. Bas, Peeters, Petra H., Khaw, Kay-Thee, Wareham, Nicholas J., Schmidt, Julie A., Aune, Dagfinn, Byrnes, Graham, Scalbert, Augustin, Agudo, Antonio, and Rinaldi, Sabina
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- 2019
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6. New insights on occupational exposure and bladder cancer risk: a pooled analysis of two Italian case–control studies
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Sciannameo, Veronica, Carta, Angela, d’Errico, Angelo, Giraudo, Maria Teresa, Fasanelli, Francesca, Arici, Cecilia, Maule, Milena, Carnà, Paolo, Destefanis, Paolo, Rolle, Luigi, Gontero, Paolo, Casetta, Giovanni, Zitella, Andrea, Cucchiarale, Giuseppina, Vineis, Paolo, Porru, Stefano, Sacerdote, Carlotta, and Ricceri, Fulvio
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- 2019
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7. Is the association between precarious employment and mental health mediated by economic difficulties in males? Results from two Italian studies
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Ferrante, Gianluigi, Fasanelli, Francesca, Gigantesco, Antonella, Ferracin, Elisa, Contoli, Benedetta, Costa, Giuseppe, Gargiulo, Lidia, Marra, Michele, Masocco, Maria, Minardi, Valentina, Violani, Cristiano, Zengarini, Nicolás, d’Errico, Angelo, and Ricceri, Fulvio
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- 2019
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8. Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk
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Johansson, Annelie, Palli, Domenico, Masala, Giovanna, Grioni, Sara, Agnoli, Claudia, Tumino, Rosario, Giurdanella, Maria Concetta, Fasanelli, Francesca, Sacerdote, Carlotta, Panico, Salvatore, Mattiello, Amalia, Polidoro, Silvia, Jones, Michael E., Schoemaker, Minouk J., Orr, Nick, Tomczyk, Katarzyna, Johnson, Nichola, Fletcher, Olivia, Perduca, Vittorio, Baglietto, Laura, Dugué, Pierre-Antoine, Southey, Melissa C., Giles, Graham G., English, Dallas R., Milne, Roger L., Severi, Gianluca, Ambatipudi, Srikant, Cuenin, Cyrille, Chajès, Veronique, Romieu, Isabelle, Herceg, Zdenko, Swerdlow, Anthony J., Vineis, Paolo, and Flanagan, James M.
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- 2019
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9. Supplemental Tables 1-3 from Added Value of Serum Hormone Measurements in Risk Prediction Models for Breast Cancer for Women Not Using Exogenous Hormones: Results from the EPIC Cohort
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Hüsing, Anika, primary, Fortner, Renée T., primary, Kühn, Tilman, primary, Overvad, Kim, primary, Tjønneland, Anne, primary, Olsen, Anja, primary, Boutron-Ruault, Marie-Christine, primary, Severi, Gianluca, primary, Fournier, Agnes, primary, Boeing, Heiner, primary, Trichopoulou, Antonia, primary, Benetou, Vassiliki, primary, Orfanos, Philippos, primary, Masala, Giovanna, primary, Pala, Valeria, primary, Tumino, Rosario, primary, Fasanelli, Francesca, primary, Panico, Salvatore, primary, Bueno de Mesquita, H. Bas, primary, Peeters, Petra H., primary, van Gills, Carla H., primary, Quirós, J. Ramón, primary, Agudo, Antonio, primary, Sánchez, Maria-Jose, primary, Chirlaque, Maria-Dolores, primary, Barricarte, Aurelio, primary, Amiano, Pilar, primary, Khaw, Kay-Tee, primary, Travis, Ruth C., primary, Dossus, Laure, primary, Li, Kuanrong, primary, Ferrari, Pietro, primary, Merritt, Melissa A., primary, Tzoulaki, Ioanna, primary, Riboli, Elio, primary, and Kaaks, Rudolf, primary
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- 2023
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10. Impact of preventable risk factors on stroke in the EPICOR study: does gender matter?
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Trajkova, Slavica, d’Errico, Angelo, Ricceri, Fulvio, Fasanelli, Francesca, Pala, Valeria, Agnoli, Claudia, Tumino, Rosario, Frasca, Graziella, Masala, Giovanna, Saieva, Calogero, Chiodini, Paolo, Mattiello, Amalia, Sacerdote, Carlotta, and Panico, Salvatore
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- 2017
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11. Hepcidin levels and gastric cancer risk in the EPIC-EurGast study
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Jakszyn, Paula, Fonseca-Nunes, Ana, Lujan-Barroso, Leila, Aranda, Núria, Tous, Mónica, Arija, Victoria, Cross, Amanda, Bueno-de-Mesquita, B(as) H., Weiderpass, Elisabete, Kühn, Tilman, Kaaks, Rudolf, Sjöberg, Klas, Ohlsson, Bodil, Tumino, Rosario, Palli, Domenico, Ricceri, Fulvio, Fasanelli, Francesca, Krogh, Vittorio, Mattiello, Amalia, Jenab, Mazda, Gunter, Marc, Perez-Cornago, Aurora, Khaw, Kay-Tee, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Trichopoulou, Antonia, Peppa, Eleni, Vasilopoulou, Effie, Boeing, Heiner, Sánchez-Cantalejo, Emilio, Huerta, José María, Dorronsoro, Miren, Barricarte, Aurelio, Quirós, José Maria, Peeters, Petra H., and Agudo, Antonio
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- 2017
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12. Applied causal inference methods for sequential mediators
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Zugna, Daniela, primary, Popovic, Maja, additional, Fasanelli, Francesca, additional, Heude, Barbara, additional, Scelo, Ghislaine, additional, and Richiardi, Lorenzo, additional
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- 2022
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13. Applied causal inference methods for sequential mediators
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Zugna, Daniela, primary, Popovic, Maja, additional, Heude, Barbara, additional, Fasanelli, Francesca, additional, Scelo, Ghislaine, additional, and Richiardi, Lorenzo, additional
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- 2021
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14. Applied causal inference methods for sequential mediators
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Popovic, Maja, primary, Richiardi, Lorenzo, additional, Scelo, Ghislaine, additional, Fasanelli, Francesca, additional, Heude, Barbara, additional, and Zugna, Daniela, additional
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- 2021
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15. Risk of second primary malignancies in women with breast cancer: Results from the European prospective investigation into cancer and nutrition (EPIC)
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Ricceri, Fulvio, Fasanelli, Francesca, Giraudo, Maria Teresa, Sieri, Sabina, Tumino, Rosario, Mattiello, Amalia, Vagliano, Liliana, Masala, Giovanna, Quirós, Ramón J., Travier, Noemie, Sánchez, María-José, Larranaga, Nerea, Chirlaque, María-Dolores, Ardanaz, Eva, Tjonneland, Anne, Olsen, Anja, Overvad, Kim, Chang-Claude, Jenny, Kaaks, Rudolf, Boeing, Heiner, Clavel-Chapelon, Françoise, Kvaskoff, Marina, Dossus, Laure, Trichopoulou, Antonia, Benetou, Vassiliki, Adarakis, George, Bueno-de-Mesquita, H. B(as), Peeters, Petra H., Sund, Malin, Andersson, Anne, Borgquist, Signe, Butt, Salma, Weiderpass, Elisabete, Skeie, Guri, Khaw, Kay-Tee, Travis, Ruth C., Rinaldi, Sabina, Romieu, Isabelle, Gunter, Marc, Kadi, Mai, Riboli, Elio, Vineis, Paolo, and Sacerdote, Carlotta
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- 2015
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16. Additional file 1: of Is the association between precarious employment and mental health mediated by economic difficulties in males? Results from two Italian studies
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Ferrante, Gianluigi, Fasanelli, Francesca, Gigantesco, Antonella, Ferracin, Elisa, Contoli, Benedetta, Costa, Giuseppe, Gargiulo, Lidia, Marra, Michele, Masocco, Maria, Minardi, Valentina, Violani, Cristiano, NicolĂĄs Zengarini, DâErrico, Angelo, and Ricceri, Fulvio
- Abstract
In this file, the theoretical explanation of mediation analysis is presented. (DOCX 14 kb)
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- 2019
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17. Association between physical activity and risk of hepatobiliary cancers : A multinational cohort study
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Baumeister, Sebastian E, Schlesinger, Sabrina, Aleksandrova, Krasimira, Jochem, Carmen, Jenab, Mazda, Gunter, Marc J, Overvad, Kim, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, Carbonnel, Franck, Fournier, Agnès, Kühn, Tilman, Kaaks, Rudolf, Pischon, Tobias, Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, La Vecchia, Carlo, Masala, Giovanna, Panico, Salvatore, Fasanelli, Francesca, Tumino, Rosario, Grioni, Sara, Bueno de Mesquita, Bas, Vermeulen, Roel, May, Anne M, Borch, Kristin B, Oyeyemi, Sunday O, Ardanaz, Eva, Rodríguez-Barranco, Miguel, Dolores Chirlaque López, María, Felez-Nobrega, Mireia, Sonestedt, Emily, Ohlsson, Bodil, Hemmingsson, Oskar, Werner, Mårten, Perez-Cornago, Aurora, Ferrari, Pietro, Stepien, Magdalena, Freisling, Heinz, Tsilidis, Konstantinos K, Ward, Heather, Riboli, Elio, Weiderpass, Elisabete, Leitzmann, Michael F, Baumeister, Sebastian E, Schlesinger, Sabrina, Aleksandrova, Krasimira, Jochem, Carmen, Jenab, Mazda, Gunter, Marc J, Overvad, Kim, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, Carbonnel, Franck, Fournier, Agnès, Kühn, Tilman, Kaaks, Rudolf, Pischon, Tobias, Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, La Vecchia, Carlo, Masala, Giovanna, Panico, Salvatore, Fasanelli, Francesca, Tumino, Rosario, Grioni, Sara, Bueno de Mesquita, Bas, Vermeulen, Roel, May, Anne M, Borch, Kristin B, Oyeyemi, Sunday O, Ardanaz, Eva, Rodríguez-Barranco, Miguel, Dolores Chirlaque López, María, Felez-Nobrega, Mireia, Sonestedt, Emily, Ohlsson, Bodil, Hemmingsson, Oskar, Werner, Mårten, Perez-Cornago, Aurora, Ferrari, Pietro, Stepien, Magdalena, Freisling, Heinz, Tsilidis, Konstantinos K, Ward, Heather, Riboli, Elio, Weiderpass, Elisabete, and Leitzmann, Michael F
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- 2019
18. Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study
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One Health Chemisch, dIRAS RA-2, Baumeister, Sebastian E., Schlesinger, Sabrina, Aleksandrova, Krasimira, Jochem, Carmen, Jenab, Mazda, Gunter, Marc J., Overvad, Kim, Tjønneland, Anne, Boutron-Ruault, Marie Christine, Carbonnel, Franck, Fournier, Agnès, Kühn, Tilman, Kaaks, Rudolf, Pischon, Tobias, Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, La Vecchia, Carlo, Masala, Giovanna, Panico, Salvatore, Fasanelli, Francesca, Tumino, Rosario, Grioni, Sara, Bueno de Mesquita, Bas, Vermeulen, Roel, May, Anne M., Borch, Kristin B., Oyeyemi, Sunday O., Ardanaz, Eva, Rodríguez-Barranco, Miguel, Dolores Chirlaque López, María, Felez-Nobrega, Mireia, Sonestedt, Emily, Ohlsson, Bodil, Hemmingsson, Oskar, Werner, Mårten, Perez-Cornago, Aurora, Ferrari, Pietro, Stepien, Magdalena, Freisling, Heinz, Tsilidis, Konstantinos K., Ward, Heather, Riboli, Elio, Weiderpass, Elisabete, Leitzmann, Michael F., One Health Chemisch, dIRAS RA-2, Baumeister, Sebastian E., Schlesinger, Sabrina, Aleksandrova, Krasimira, Jochem, Carmen, Jenab, Mazda, Gunter, Marc J., Overvad, Kim, Tjønneland, Anne, Boutron-Ruault, Marie Christine, Carbonnel, Franck, Fournier, Agnès, Kühn, Tilman, Kaaks, Rudolf, Pischon, Tobias, Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, La Vecchia, Carlo, Masala, Giovanna, Panico, Salvatore, Fasanelli, Francesca, Tumino, Rosario, Grioni, Sara, Bueno de Mesquita, Bas, Vermeulen, Roel, May, Anne M., Borch, Kristin B., Oyeyemi, Sunday O., Ardanaz, Eva, Rodríguez-Barranco, Miguel, Dolores Chirlaque López, María, Felez-Nobrega, Mireia, Sonestedt, Emily, Ohlsson, Bodil, Hemmingsson, Oskar, Werner, Mårten, Perez-Cornago, Aurora, Ferrari, Pietro, Stepien, Magdalena, Freisling, Heinz, Tsilidis, Konstantinos K., Ward, Heather, Riboli, Elio, Weiderpass, Elisabete, and Leitzmann, Michael F.
- Published
- 2019
19. Heterogeneity of Colorectal Cancer Risk Factors by Anatomical Subsite in 10 European Countries: A Multinational Cohort Study
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MS MDL 1, EUPG team 2a, Epi Kanker Team 1, Cancer, JC onderzoeksprogramma Kanker, Murphy, Neil, Ward, Heather A., Jenab, Mazda, Rothwell, Joseph A., Boutron-Ruault, Marie Christine, Carbonnel, Franck, Kvaskoff, Marina, Kaaks, Rudolf, Kühn, Tilman, Boeing, Heiner, Aleksandrova, Krasimira, Weiderpass, Elisabete, Skeie, Guri, Borch, Kristin Benjaminsen, Tjønneland, Anne, Kyrø, Cecilie, Overvad, Kim, Dahm, Christina C., Jakszyn, Paula, Sánchez, Maria Jose, Gil, Leire, Huerta, José M., Barricarte, Aurelio, Quirós, J. Ramón, Khaw, Kay Tee, Wareham, Nick, Bradbury, Kathryn E., Trichopoulou, Antonia, La Vecchia, Carlo, Karakatsani, Anna, Palli, Domenico, Grioni, Sara, Tumino, Rosario, Fasanelli, Francesca, Panico, Salvatore, Bueno-de-Mesquita, Bas, Peeters, Petra H., Gylling, Björn, Myte, Robin, Jirström, Karin, Berntsson, Jonna, Xue, Xiaonan, Riboli, Elio, Cross, Amanda J., Gunter, Marc J., MS MDL 1, EUPG team 2a, Epi Kanker Team 1, Cancer, JC onderzoeksprogramma Kanker, Murphy, Neil, Ward, Heather A., Jenab, Mazda, Rothwell, Joseph A., Boutron-Ruault, Marie Christine, Carbonnel, Franck, Kvaskoff, Marina, Kaaks, Rudolf, Kühn, Tilman, Boeing, Heiner, Aleksandrova, Krasimira, Weiderpass, Elisabete, Skeie, Guri, Borch, Kristin Benjaminsen, Tjønneland, Anne, Kyrø, Cecilie, Overvad, Kim, Dahm, Christina C., Jakszyn, Paula, Sánchez, Maria Jose, Gil, Leire, Huerta, José M., Barricarte, Aurelio, Quirós, J. Ramón, Khaw, Kay Tee, Wareham, Nick, Bradbury, Kathryn E., Trichopoulou, Antonia, La Vecchia, Carlo, Karakatsani, Anna, Palli, Domenico, Grioni, Sara, Tumino, Rosario, Fasanelli, Francesca, Panico, Salvatore, Bueno-de-Mesquita, Bas, Peeters, Petra H., Gylling, Björn, Myte, Robin, Jirström, Karin, Berntsson, Jonna, Xue, Xiaonan, Riboli, Elio, Cross, Amanda J., and Gunter, Marc J.
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- 2019
20. Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study
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MS MDL 1, Epi Infectieziekten Team 2, Epi Kanker Team 1, Cancer, JC onderzoeksprogramma Kanker, Zamora-Ros, Raul, Alghamdi, Muath A., Cayssials, Valerie, Franceschi, Silvia, Almquist, Martin, Hennings, Joakim, Sandström, Maria, Tsilidis, Konstantinos K., Weiderpass, Elisabete, Boutron-Ruault, Marie Christine, Hammer Bech, Bodil, Overvad, Kim, Tjønneland, Anne, Petersen, Kristina E.N., Mancini, Francesca Romana, Mahamat-Saleh, Yahya, Bonnet, Fabrice, Kühn, Tilman, Fortner, Renée T., Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, Martimianaki, Georgia, Masala, Giovanna, Grioni, Sara, Panico, Salvatore, Tumino, Rosario, Fasanelli, Francesca, Skeie, Guri, Braaten, Tonje, Lasheras, Cristina, Salamanca-Fernández, Elena, Amiano, Pilar, Chirlaque, Maria Dolores, Barricarte, Aurelio, Manjer, Jonas, Wallström, Peter, Bueno-de-Mesquita, H. Bas, Peeters, Petra H., Khaw, Kay Thee, Wareham, Nicholas J., Schmidt, Julie A., Aune, Dagfinn, Byrnes, Graham, Scalbert, Augustin, Agudo, Antonio, Rinaldi, Sabina, MS MDL 1, Epi Infectieziekten Team 2, Epi Kanker Team 1, Cancer, JC onderzoeksprogramma Kanker, Zamora-Ros, Raul, Alghamdi, Muath A., Cayssials, Valerie, Franceschi, Silvia, Almquist, Martin, Hennings, Joakim, Sandström, Maria, Tsilidis, Konstantinos K., Weiderpass, Elisabete, Boutron-Ruault, Marie Christine, Hammer Bech, Bodil, Overvad, Kim, Tjønneland, Anne, Petersen, Kristina E.N., Mancini, Francesca Romana, Mahamat-Saleh, Yahya, Bonnet, Fabrice, Kühn, Tilman, Fortner, Renée T., Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, Martimianaki, Georgia, Masala, Giovanna, Grioni, Sara, Panico, Salvatore, Tumino, Rosario, Fasanelli, Francesca, Skeie, Guri, Braaten, Tonje, Lasheras, Cristina, Salamanca-Fernández, Elena, Amiano, Pilar, Chirlaque, Maria Dolores, Barricarte, Aurelio, Manjer, Jonas, Wallström, Peter, Bueno-de-Mesquita, H. Bas, Peeters, Petra H., Khaw, Kay Thee, Wareham, Nicholas J., Schmidt, Julie A., Aune, Dagfinn, Byrnes, Graham, Scalbert, Augustin, Agudo, Antonio, and Rinaldi, Sabina
- Published
- 2019
21. Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study
- Author
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MS MDL 1, Public Health Practice, Epidemiology & Health Economics, Cancer, JC onderzoeksprogramma Kanker, Baumeister, Sebastian E, Schlesinger, Sabrina, Aleksandrova, Krasimira, Jochem, Carmen, Jenab, Mazda, Gunter, Marc J, Overvad, Kim, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, Carbonnel, Franck, Fournier, Agnès, Kühn, Tilman, Kaaks, Rudolf, Pischon, Tobias, Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, La Vecchia, Carlo, Masala, Giovanna, Panico, Salvatore, Fasanelli, Francesca, Tumino, Rosario, Grioni, Sara, Bueno de Mesquita, Bas, Vermeulen, Roel, May, Anne M, Borch, Kristin B, Oyeyemi, Sunday O, Ardanaz, Eva, Rodríguez-Barranco, Miguel, Dolores Chirlaque López, María, Felez-Nobrega, Mireia, Sonestedt, Emily, Ohlsson, Bodil, Hemmingsson, Oskar, Werner, Mårten, Perez-Cornago, Aurora, Ferrari, Pietro, Stepien, Magdalena, Freisling, Heinz, Tsilidis, Konstantinos K, Ward, Heather, Riboli, Elio, Weiderpass, Elisabete, Leitzmann, Michael F, MS MDL 1, Public Health Practice, Epidemiology & Health Economics, Cancer, JC onderzoeksprogramma Kanker, Baumeister, Sebastian E, Schlesinger, Sabrina, Aleksandrova, Krasimira, Jochem, Carmen, Jenab, Mazda, Gunter, Marc J, Overvad, Kim, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, Carbonnel, Franck, Fournier, Agnès, Kühn, Tilman, Kaaks, Rudolf, Pischon, Tobias, Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, La Vecchia, Carlo, Masala, Giovanna, Panico, Salvatore, Fasanelli, Francesca, Tumino, Rosario, Grioni, Sara, Bueno de Mesquita, Bas, Vermeulen, Roel, May, Anne M, Borch, Kristin B, Oyeyemi, Sunday O, Ardanaz, Eva, Rodríguez-Barranco, Miguel, Dolores Chirlaque López, María, Felez-Nobrega, Mireia, Sonestedt, Emily, Ohlsson, Bodil, Hemmingsson, Oskar, Werner, Mårten, Perez-Cornago, Aurora, Ferrari, Pietro, Stepien, Magdalena, Freisling, Heinz, Tsilidis, Konstantinos K, Ward, Heather, Riboli, Elio, Weiderpass, Elisabete, and Leitzmann, Michael F
- Published
- 2019
22. DNA methylation, colon cancer and Mediterranean diet: results from the EPIC-Italy cohort
- Author
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Fasanelli, Francesca, primary, Giraudo, Maria Teresa, additional, Vineis, Paolo, additional, Fiano, Valentina, additional, Fiorito, Giovanni, additional, Grasso, Chiara, additional, Polidoro, Silvia, additional, Trevisan, Morena, additional, Grioni, Sara, additional, Krogh, Vittorio, additional, Mattiello, Amalia, additional, Panico, Salvatore, additional, Giurdanella, Maria Concetta, additional, Tumino, Rosario, additional, De Marco, Laura, additional, Ricceri, Fulvio, additional, and Sacerdote, Carlotta, additional
- Published
- 2019
- Full Text
- View/download PDF
23. Differentially methylated DNA regions in early childhood wheezing: An epigenome‐wide study using saliva
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Popovic, Maja, primary, Fiano, Valentina, additional, Fasanelli, Francesca, additional, Trevisan, Morena, additional, Grasso, Chiara, additional, Assumma, Manuela Bianca, additional, Gillio‐Tos, Anna, additional, Polidoro, Silvia, additional, De Marco, Laura, additional, Rusconi, Franca, additional, Merletti, Franco, additional, Zugna, Daniela, additional, and Richiardi, Lorenzo, additional
- Published
- 2019
- Full Text
- View/download PDF
24. Marginal Time-Dependent Causal Effects in Mediation Analysis With Survival Data
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Fasanelli, Francesca, primary, Giraudo, Maria Teresa, additional, Ricceri, Fulvio, additional, Valeri, Linda, additional, and Zugna, Daniela, additional
- Published
- 2019
- Full Text
- View/download PDF
25. Diet quality scores and prediction of all-cause, cardiovascular and cancer mortality in a pan-european cohort study
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Lassale, Camille, Gunter, Marc J., Romaguera, Dora, Peelen, Linda M., Van der Schouw, Yvonne T., Beulens, Joline W. J., Freisling, Heinz, Muller, David C., Ferrari, Pietro, Huybrechts, Inge, Fagherazzi, Guy, Boutron-Ruault, Marie-Christine, Affret, Aurelie, Overvad, Kim, Dahm, Christina C., Olsen, Anja, Roswall, Nina, Tsilidis, Konstantinos K., Katzke, Verena A., Kuehn, Tilman, Buijsse, Brian, Quiros, Jose-Ramon, Sanchez-Cantalejo, Emilio, Etxezarreta, Nerea, Maria Huerta, Jose, Barricarte, Aurelio, Bonet, Catalina, Khaw, Kay-Tee, Key, Timothy J., Trichopoulou, Antonia, Bamia, Christina, Lagiou, Pagona, Palli, Domenico, Agnoli, Claudia, Tumino, Rosario, Fasanelli, Francesca, Panico, Salvatore, Bueno-de-Mesquita, H. Bas, Boer, Jolanda M. A., Sonestedt, Emily, Nilsson, Lena Maria, Renstrom, Frida, Weiderpass, Elisabete, Skeie, Guri, Lund, Eiliv, Moons, Karel G. M., Riboli, Elio, Tzoulaki, Ioanna, Khaw, Kay-Tee [0000-0002-8802-2903], Apollo - University of Cambridge Repository, Epidemiology and Data Science, EMGO - Lifestyle, overweight and diabetes, Lassale, Camille, Gunter, Marc J, Romaguera, Dora, Peelen, Linda M, Van der Schouw, Yvonne T, Beulens, Joline W. J, Freisling, Heinz, Muller, David C, Ferrari, Pietro, Huybrechts, Inge, Fagherazzi, Guy, Boutron Ruault, Marie Christine, Affret, Aurélie, Overvad, Kim, Dahm, Christina C, Olsen, Anja, Roswall, Nina, Tsilidis, Konstantinos K, Katzke, Verena A, Kühn, Tilman, Buijsse, Brian, Quirós, José Ramón, Sánchez Cantalejo, Emilio, Etxezarreta, Nerea, Huerta, José María, Barricarte, Aurelio, Bonet, Catalina, Khaw, Kay Tee, Key, Timothy J, Trichopoulou, Antonia, Bamia, Christina, Lagiou, Pagona, Palli, Domenico, Agnoli, Claudia, Tumino, Rosario, Fasanelli, Francesca, Panico, Salvatore, Bueno de Mesquita, H. Ba, Boer, Jolanda M. A, Sonestedt, Emily, Nilsson, Lena Maria, Renström, Frida, Weiderpass, Elisabete, Skeie, Guri, Lund, Eiliv, Moons, Karel G. M, Riboli, Elio, Tzoulaki, Ioanna, [Lassale,C, Gunter,MJ, Romaguera,D, Tsilidis,KK, Riboli,E, Tzoulaki,I] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, United Kingdom. [Romaguera,D] Instituto de Investigación Sanitaria de Palma (IdISPa), Palma de Mallorca, Spain. [Romaguera,D, Quirós,J, Sánchez-Cantalejo,E, Etxezarreta,N, Huerta,JM, Barricarte,A, Bonet,C] CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. [Peelen,LM, Schouw,ITV, Beulens,JWJ, Moons,KGM] Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands.[Freisling,H, Muller,DC, Ferrari,P, Huybrechts,I] International Agency for Research on Cancer, Lyon, France. [Fagherazz,G, Boutron-Ruault,M, Affret,A] Institut National de la Santé et de la Recherche Médicale, Center for Research in Epidemiology and Population, Health, Villejuif, France. Institut Gustave Roussy, Villejuif, France. Paris South University, Unité Mixte de Recherche, Villejuif, France. [Overvad,K, Dahm,CC] Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark. [Olsen,A, Roswall,N] Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen, Denmark. [Tsilidis,KK] German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany. [Katzke,VA, Kühn,T] Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke German Institute of Human Nutrition, Potsdam, Germany. [Buijsse,B] Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece. [Quirós,R] Public Health Directorate, Asturias, Oviedo, Spain. [Sánchez-Cantalejo,E] Andalusian School of Public Health, Granada, Spain. [Etxezarreta,N] Public Health Direction and Biodonostia Basque Regional Health Department, San Sebastian, Spain. [Huerta,JM] Department of Epidemiology, Murcia Regional Health Council, Murcia, Spain. [Barricarte,A] Navarre Public Health Institute, Pamplona, Spain. [Bonet,C] Unit of Nutrition, Environment and Cancer, Catalan Institute of Oncology, Barcelona, Spain. [Khaw,K] University of Cambridge School of Clinical Medicine, Clinical Gerontology Unit, Cambridge, United Kingdom. [Key,J] Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, United Kingdom. [Trichopoulou,A, Bamia,C, Lagiou,P] Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece. Hellenic Health Foundation, Athens, Greece. [Palli,D] Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute—ISPO, Florence, Italy. [Agnoli,C] Epidemiology and Prevention Unit, Department of Preventive and Predictive Medicine, Foundation of the Carlo Besta Neurological Institute, Milan, Italy. [Tumino,R] Cancer Registry and Histopathology Unit, 'Civic MP Arezzo' Hospital, Ragusa, Italy. [Fasanelli,F] Human Genetics Foundation, Turin, Italy. [Bueno-de-Mesquita,HB, Boer,JMA] Center for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment, Bilthoven, Netherlands. [Sonestedt,E] Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden. [Nilsson,LM, Renström,F] Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Sweden. [Weiderpass,E, Skeie,G, Lund,E] Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway. [Weiderpass,E] Department of Research, Cancer Registry of Norway, Oslo, Norway. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki, Finland., Funding: The coordination of EPIC is financially supported by the European Commission (DGSANCO) and the International Agency for Research on Cancer. The national cohorts are supported by Danish Cancer Society (Denmark), Ligue Contre le Cancer, Institut Gustave Roussy, Mutuelle Générale de l’Education Nationale, Institut National de la Santé et de la Recherche Médicale (INSERM) (France), German Cancer Aid, German Cancer Research Center (DKFZ), Federal Ministry of Education and Research (BMBF), Deutsche Krebshilfe, Deutsches Krebsforschungszentrum and Federal Ministry of Education and Research (Germany), the Hellenic Health Foundation (Greece), Associazione Italiana per la Ricerca sul Cancro-AIRC-Italy and National Research Council (Italy), Dutch Ministry of Public Health, Welfare and Sports (VWS), Netherlands Cancer Registry (NKR), LK Research Funds, Dutch Prevention Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund (WCRF), Statistics Netherlands (The Netherlands), Health Research Fund (FIS), PI13/00061 to Granada, Regional Governments of Andalucía, Asturias, Basque Country, Murcia (no. 6236) and Navarra, ISCIII RETIC (RD06/0020) (Spain), Swedish Cancer Society, Swedish Research Council and County Councils of Skåne and Västerbotten (Sweden), Cancer Research UK (14136 to EPIC-Norfolk, and C570/ A16491 and C8221/A19170 to EPIC-Oxford), Medical Research Council (1000143 to EPIC-Norfolk, MR/ M012190/1 to EPIC-Oxford) (United Kingdom).
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Male ,humanos ,Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings] ,Social Sciences ,Índice de masa corporal ,Global Health ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings] ,Cohort Studies ,distribución por sexos ,Mathematical and Statistical Techniques ,Sociology ,Risk Factors ,Neoplasms ,Medicine and Health Sciences ,Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Movement::Motor Activity [Medical Subject Headings] ,Public and Occupational Health ,Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Nutritional Status [Medical Subject Headings] ,Estado Nutricional ,estudios de cohortes ,mediana edad ,Factores de Riesgo ,neoplasias ,Medicine(all) ,Nutrition and Dietetics ,VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801 ,Agricultural and Biological Sciences(all) ,dieta ,Agriculture ,Public Health, Global Health, Social Medicine and Epidemiology ,Estudios Prospectivos ,Plants ,Diseases::Neoplasms [Medical Subject Headings] ,Middle Aged ,Neoplasias ,Näringslära ,Cardiovascular Diseases ,Hábitos alimenticios ,estilo de vida ,Physical Sciences ,Medicine ,Dieta ,Female ,Statistics (Mathematics) ,Research Article ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Prospective Studies [Medical Subject Headings] ,General Science & Technology ,Science ,Estudios de cohortes ,European Continental Ancestry Group ,Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Habits::Smoking [Medical Subject Headings] ,enfermedades cardiovasculares ,Crops ,Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings] ,Research and Analysis Methods ,White People ,Education ,Fruits ,Age Distribution ,distribución por edades ,SDG 3 - Good Health and Well-being ,MD Multidisciplinary ,Anatomy::Cardiovascular System [Medical Subject Headings] ,Journal Article ,factores de riesgo ,Humans ,Statistical Methods ,Sex Distribution ,Life Style ,Educational Attainment ,Nutrition ,Sistema cardiovascular ,Biochemistry, Genetics and Molecular Biology(all) ,Organisms ,Biology and Life Sciences ,Physical Activity ,Nutrients ,Actividad motora ,Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Feeding Behavior::Food Habits [Medical Subject Headings] ,Diet ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings] ,Hábito de Fumar ,VDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801 ,grupo de ascendencia continental europea ,Mathematics ,Forecasting ,Crop Science - Abstract
Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective Investigation into Cancer and Nutrition, followed-up for a median of 12.8y. All dietary scores studied showed significant inverse associations with all outcomes. The range of HRs (95% CI) in the top vs. lowest quartile of dietary scores in a composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity and study centre) was 0.75 (0.72-0.79) to 0.88 (0.84-0.92) for all-cause, 0.76 (0.69-0.83) to 0.84 (0.76-0.92) for CVD and 0.78 (0.73-0.83) to 0.91 (0.85-0.97) for cancer mortality. Models with dietary scores alone showed low discrimination, but composite models also including age, sex and other non-invasive factors showed good discrimination and calibration, which varied little between different diet scores examined. Mean C-statistic of full models was 0.73, 0.80 and 0.71 for all-cause, CVD and cancer mortality. Dietary scores have poor predictive performance for 10-year mortality risk when used in isolation but display good predictive ability in combination with other non-invasive common risk factors., The coordination of EPIC is financially supported by the European Commission (D-GSANCO) and the International Agency for Research on Cancer. The national cohorts are supported by Danish Cancer Society (Denmark); Ligue Contre le Cancer, Institut Gustave Roussy, Mutuelle Generale de l'Education Nationale, Institut National de la Sante et de la Recherche Medicale (INSERM) (France); German Cancer Aid, German Cancer Research Center (DKFZ), Federal Ministry of Education and Research (BMBF), Deutsche Krebshilfe, Deutsches Krebsforschungszentrum and Federal Ministry of Education and Research (Germany); the Hellenic Health Foundation (Greece); Associazione Italiana per la Ricerca sul Cancro-AIRC- Italy and National Research Council (Italy); Dutch Ministry of Public Health, Welfare and Sports (VWS), Netherlands Cancer Registry (NKR), LK Research Funds, Dutch Prevention Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund (WCRF), Statistics Netherlands (The Netherlands); Health Research Fund (FIS), PI13/00061 to Granada, Regional Governments of Andalucia, Asturias, Basque Country, Murcia (no. 6236) and Navarra, ISCIII RETIC (RD06/0020) (Spain); Swedish Cancer Society, Swedish Research Council and County Councils of Skane and Vasterbotten (Sweden); Cancer Research UK (14136 to EPIC-Norfolk; C570/A16491 and C8221/A19170 to EPIC-Oxford), Medical Research Council (1000143 to EPIC-Norfolk, MR/M012190/1 to EPIC-Oxford) (United Kingdom).
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- 2016
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26. Additional file 1: Table S1. of Diet and endometrial cancer: a focus on the role of fruit and vegetable intake, Mediterranean diet and dietary inflammatory index in the endometrial cancer risk
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Ricceri, Fulvio, Giraudo, Maria, Fasanelli, Francesca, Milanese, Dario, Sciannameo, Veronica, Fiorini, Laura, and Sacerdote, Carlotta
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Odds ratios (OR) and 95% confidence Intervals (CI) by fruit and vegetable quintiles, Mediterranean diet index, and dietary inflammation index quintiles. (PDF 8Â kb)
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- 2017
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27. Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort
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Zamora-Ros, Raul Barupal, Dinesh K. Rothwell, Joseph A. and Jenab, Mazda Fedirko, Veronika Romieu, Isabelle and Aleksandrova, Krasimira Overvad, Kim Kyro, Cecilie and Tjonneland, Anne Affret, Aurelie His, Mathilde and Boutron-Ruault, Marie-Christine Katzke, Verena Kuehn, Tilman and Boeing, Heiner Trichopoulou, Antonia Naska, Androniki and Kritikou, Maria Saieva, Calogero Agnoli, Claudia de Magistris, Maria Santucci Tumino, Rosario Fasanelli, Francesca and Weiderpass, Elisabete Skeie, Guri Merino, Susana and Jakszyn, Paula Sanchez, Maria-Jose Dorronsoro, Miren and Navarro, Carmen Ardanaz, Eva Sonestedt, Emily Ericson, Ulrika Nilsson, Lena Maria Boden, Stina Bueno-de-Mesquita, H. B. (as) Peeters, Petra H. Perez-Cornago, Aurora Wareham, Nicholas J. Khaw, Kay-Thee Freisling, Heinz Cross, Amanda J. and Riboli, Elio Scalbert, Augustin
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fungi ,food and beverages ,heterocyclic compounds - Abstract
Flavonoids have been shown to inhibit colon cancer cell proliferation in vitro and protect against colorectal carcinogenesis in animal models. However, epidemiological evidence on the potential role of flavonoid intake in colorectal cancer (CRC) development remains sparse and inconsistent. We evaluated the association between dietary intakes of total flavonoids and their subclasses and risk of development of CRC, within the European Prospective Investigation into Cancer and Nutrition (EPIC) study. A cohort of 477,312 adult men and women were recruited in 10 European countries. At baseline, dietary intakes of total flavonoids and individual subclasses were estimated using centre-specific validated dietary questionnaires and composition data from the Phenol-Explorer database. During an average of 11 years of follow-up, 4,517 new cases of primary CRC were identified, of which 2,869 were colon (proximal = 1,298 and distal = 1,266) and 1,648 rectal tumours. No association was found between total flavonoid intake and the risk of overall CRC (HR for comparison of extreme quintiles 1.05, 95% CI 0.93-1.18; p-trend = 0.58) or any CRC subtype. No association was also observed with any intake of individual flavonoid subclasses. Similar results were observed for flavonoid intake expressed as glycosides or aglycone equivalents. Intake of total flavonoids and flavonoid subclasses, as estimated from dietary questionnaires, did not show any association with risk of CRC development.
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- 2017
28. International Journal of Cancer / DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk
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Baglietto, Laura, Ponzi, Erica, Haycock, Philip, Hodge, Allison, Assumma, Manuela Bianca, Jung, Chol-Hee, Chung, Jessica, Fasanelli, Francesca, Guida, Florence, Campanella, Gianluca, Chadeau-Hyam, Marc, Grankvist, Kjell, Johansson, Mikael, Ala, Ugo, Provero, Paolo, Wo, Ee Ming, Joo, Jihoon, and English, Dallas R.
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DNA methylation changes are associated with cigarette smoking. We used the Illumina Infinium HumanMethylation450 array to determine whether methylation in DNA from pre-diagnostic, peripheral blood samples is associated with lung cancer risk. We used a case-control study nested within the EPIC-Italy cohort and a study within the MCCS cohort as discovery sets (a total of 552 case-control pairs). We validated the top signals in 429 case-control pairs from another 3 studies. We identified six CpGs for which hypomethylation was associated with lung cancer risk: cg05575921 in the AHRR gene (p-valuepooled =4 10-17 ), cg03636183 in the F2RL3 gene (p-valuepooled =2 10 - 13 ), cg21566642 and cg05951221 in 2q37.1 (p-valuepooled =7 10-16 and 1 10-11 respectively), cg06126421 in 6p21.33 (p-valuepooled =2 10-15 ) and cg23387569 in 12q14.1 (p-valuepooled =5 10-7 ). For cg05951221 and cg23387569 the strength of association was virtually identical in never and current smokers. For all these CpGs except for cg23387569, the methylation levels were different across smoking categories in controls (p-valuesheterogeneity 1.8 x10 - 7 ), were lowest for current smokers and increased with time since quitting for former smokers. We observed a gain in discrimination between cases and controls measured by the area under the ROC curve of at least 8% (p-values0.003) in former smokers by adding methylation at the 6 CpGs into risk prediction models including smoking status and number of pack-years. Our findings provide convincing evidence that smoking and possibly other factors lead to DNA methylation changes measurable in peripheral blood that may improve prediction of lung cancer risk. (VLID)2220247
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- 2017
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29. Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study
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Zamora-Ros, Raul, primary, Alghamdi, Muath A., additional, Cayssials, Valerie, additional, Franceschi, Silvia, additional, Almquist, Martin, additional, Hennings, Joakim, additional, Sandström, Maria, additional, Tsilidis, Konstantinos K., additional, Weiderpass, Elisabete, additional, Boutron-Ruault, Marie-Christine, additional, Hammer Bech, Bodil, additional, Overvad, Kim, additional, Tjønneland, Anne, additional, Petersen, Kristina E. N., additional, Mancini, Francesca Romana, additional, Mahamat-Saleh, Yahya, additional, Bonnet, Fabrice, additional, Kühn, Tilman, additional, Fortner, Renée T., additional, Boeing, Heiner, additional, Trichopoulou, Antonia, additional, Bamia, Christina, additional, Martimianaki, Georgia, additional, Masala, Giovanna, additional, Grioni, Sara, additional, Panico, Salvatore, additional, Tumino, Rosario, additional, Fasanelli, Francesca, additional, Skeie, Guri, additional, Braaten, Tonje, additional, Lasheras, Cristina, additional, Salamanca-Fernández, Elena, additional, Amiano, Pilar, additional, Chirlaque, Maria-Dolores, additional, Barricarte, Aurelio, additional, Manjer, Jonas, additional, Wallström, Peter, additional, Bueno-de-Mesquita, H. Bas, additional, Peeters, Petra H., additional, Khaw, Kay-Thee, additional, Wareham, Nicholas J., additional, Schmidt, Julie A., additional, Aune, Dagfinn, additional, Byrnes, Graham, additional, Scalbert, Augustin, additional, Agudo, Antonio, additional, and Rinaldi, Sabina, additional
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- 2018
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30. New insights on occupational exposure and bladder cancer risk: a pooled analysis of two Italian case–control studies
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Sciannameo, Veronica, primary, Carta, Angela, additional, d’Errico, Angelo, additional, Giraudo, Maria Teresa, additional, Fasanelli, Francesca, additional, Arici, Cecilia, additional, Maule, Milena, additional, Carnà, Paolo, additional, Destefanis, Paolo, additional, Rolle, Luigi, additional, Gontero, Paolo, additional, Casetta, Giovanni, additional, Zitella, Andrea, additional, Cucchiarale, Giuseppina, additional, Vineis, Paolo, additional, Porru, Stefano, additional, Sacerdote, Carlotta, additional, and Ricceri, Fulvio, additional
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- 2018
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31. Abstract 5316: DNA methylation index of lifetime estrogen exposure in breast cancer
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Johansson, Annelie, primary, Palli, Domenico, additional, Masala, Giovanna, additional, Grioni, Sara, additional, Agnoli, Claudia, additional, Tumino, Rosario, additional, Giurdanella, Maria Concetta, additional, Fasanelli, Francesca, additional, Sacerdote, Carlotta, additional, Panico, Salvatore, additional, Mattiello, Amalia, additional, Swerdlow, Anthony, additional, Schoemaker, Minouk, additional, Jones, Michael, additional, Orr, Nick, additional, Fletcher, Olivia, additional, Johnson, Nichola, additional, Tomczyk, Katarzyna, additional, Vineis, Paolo, additional, and Flanagan, James M., additional
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- 2018
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32. DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk
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Baglietto, Laura, Ponzi, Erica, Haycock, Philip, Hodge, Allison, Bianca Assumma, Manuela, Jung, Chol-Hee, Chung, Jessica, Fasanelli, Francesca, Guida, Florence, Campanella, Gianluca, Chadeau-Hyam, Marc, Grankvist, Kjell, Johansson, Mikael, Ala, Ugo, Provero, Paolo, Wong, Ee Ming, Joo, Jihoon, English, Dallas R, Kazmi, Nabila, Lund, Eiliv, Faltus, Christian, Kaaks, Rudolf, Risch, Angela, Barrdahl, Myrto, Sandanger, Torkjel M, Southey, Melissa C, Giles, Graham G, Johansson, Mattias, Vineis, Paolo, Polidoro, Silvia, Relton, Caroline L, Severi, Gianluca, Baglietto, Laura, Ponzi, Erica, Haycock, Philip, Hodge, Allison, Bianca Assumma, Manuela, Jung, Chol-Hee, Chung, Jessica, Fasanelli, Francesca, Guida, Florence, Campanella, Gianluca, Chadeau-Hyam, Marc, Grankvist, Kjell, Johansson, Mikael, Ala, Ugo, Provero, Paolo, Wong, Ee Ming, Joo, Jihoon, English, Dallas R, Kazmi, Nabila, Lund, Eiliv, Faltus, Christian, Kaaks, Rudolf, Risch, Angela, Barrdahl, Myrto, Sandanger, Torkjel M, Southey, Melissa C, Giles, Graham G, Johansson, Mattias, Vineis, Paolo, Polidoro, Silvia, Relton, Caroline L, and Severi, Gianluca
- Abstract
DNA methylation changes are associated with cigarette smoking. We used the Illumina Infinium HumanMethylation450 array to determine whether methylation in DNA from pre-diagnostic, peripheral blood samples is associated with lung cancer risk. We used a case-control study nested within the EPIC-Italy cohort and a study within the MCCS cohort as discovery sets (a total of 552 case-control pairs). We validated the top signals in 429 case-control pairs from another 3 studies. We identified six CpGs for which hypomethylation was associated with lung cancer risk: cg05575921 in the AHRR gene (p-valuepooled = 4 × 10(-17) ), cg03636183 in the F2RL3 gene (p-valuepooled = 2 × 10 (- 13) ), cg21566642 and cg05951221 in 2q37.1 (p-valuepooled = 7 × 10(-16) and 1 × 10(-11) respectively), cg06126421 in 6p21.33 (p-valuepooled = 2 × 10(-15) ) and cg23387569 in 12q14.1 (p-valuepooled = 5 × 10(-7) ). For cg05951221 and cg23387569 the strength of association was virtually identical in never and current smokers. For all these CpGs except for cg23387569, the methylation levels were different across smoking categories in controls (p-valuesheterogeneity ≤ 1.8 x10 (- 7) ), were lowest for current smokers and increased with time since quitting for former smokers. We observed a gain in discrimination between cases and controls measured by the area under the ROC curve of at least 8% (p-values ≥ 0.003) in former smokers by adding methylation at the 6 CpGs into risk prediction models including smoking status and number of pack-years. Our findings provide convincing evidence that smoking and possibly other factors lead to DNA methylation changes measurable in peripheral blood that may improve prediction of lung cancer risk.
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- 2017
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33. Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort
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Zamora-Ros, Raul, Barupal, Dinesh K., Rothwell, Joseph A., Jenab, Mazda, Fedirko, Veronika, Romieu, Isabelle, Aleksandrova, Krasimira, Overvad, Kim, Kyro, Cecilie, Tjonneland, Anne, Affret, Aurelie, His, Mathilde, Boutron-Ruault, Marie-Christine, Katzke, Verena, Kuehn, Tilman, Boeing, Heiner, Trichopoulou, Antonia, Naska, Androniki, Kritikou, Maria, Saieva, Calogero, Agnoli, Claudia, de Magistris, Maria Santucci, Tumino, Rosario, Fasanelli, Francesca, Weiderpass, Elisabete, Skeie, Guri, Merino, Susana, Jakszyn, Paula, Sanchez, Maria-Jose, Dorronsoro, Miren, Navarro, Carmen, Ardanaz, Eva, Sonestedt, Emily, Ericson, Ulrika, Nilsson, Lena Maria, Bodén, Stina, Bueno-de-Mesquita, H. B. (as), Peeters, Petra H., Perez-Cornago, Aurora, Wareham, Nicholas J., Khaw, Kay-Thee, Freisling, Heinz, Cross, Amanda J., Riboli, Elio, Scalbert, Augustin, Zamora-Ros, Raul, Barupal, Dinesh K., Rothwell, Joseph A., Jenab, Mazda, Fedirko, Veronika, Romieu, Isabelle, Aleksandrova, Krasimira, Overvad, Kim, Kyro, Cecilie, Tjonneland, Anne, Affret, Aurelie, His, Mathilde, Boutron-Ruault, Marie-Christine, Katzke, Verena, Kuehn, Tilman, Boeing, Heiner, Trichopoulou, Antonia, Naska, Androniki, Kritikou, Maria, Saieva, Calogero, Agnoli, Claudia, de Magistris, Maria Santucci, Tumino, Rosario, Fasanelli, Francesca, Weiderpass, Elisabete, Skeie, Guri, Merino, Susana, Jakszyn, Paula, Sanchez, Maria-Jose, Dorronsoro, Miren, Navarro, Carmen, Ardanaz, Eva, Sonestedt, Emily, Ericson, Ulrika, Nilsson, Lena Maria, Bodén, Stina, Bueno-de-Mesquita, H. B. (as), Peeters, Petra H., Perez-Cornago, Aurora, Wareham, Nicholas J., Khaw, Kay-Thee, Freisling, Heinz, Cross, Amanda J., Riboli, Elio, and Scalbert, Augustin
- Abstract
Flavonoids have been shown to inhibit colon cancer cell proliferation in vitro and protect against colorectal carcinogenesis in animal models. However, epidemiological evidence on the potential role of flavonoid intake in colorectal cancer (CRC) development remains sparse and inconsistent. We evaluated the association between dietary intakes of total flavonoids and their subclasses and risk of development of CRC, within the European Prospective Investigation into Cancer and Nutrition (EPIC) study. A cohort of 477,312 adult men and women were recruited in 10 European countries. At baseline, dietary intakes of total flavonoids and individual subclasses were estimated using centre-specific validated dietary questionnaires and composition data from the Phenol-Explorer database. During an average of 11 years of follow-up, 4,517 new cases of primary CRC were identified, of which 2,869 were colon (proximal = 1,298 and distal = 1,266) and 1,648 rectal tumours. No association was found between total flavonoid intake and the risk of overall CRC (HR for comparison of extreme quintiles 1.05, 95% CI 0.93-1.18; p-trend = 0.58) or any CRC subtype. No association was also observed with any intake of individual flavonoid subclasses. Similar results were observed for flavonoid intake expressed as glycosides or aglycone equivalents. Intake of total flavonoids and flavonoid subclasses, as estimated from dietary questionnaires, did not show any association with risk of CRC development.
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- 2017
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34. Added value of serum hormone measurements in risk prediction models for breast cancer for women not using exogenous hormones : Results from the EPIC cohort
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Husing, Anika, Fortner, Renee T, Kuhn, Tilman, Overvad, Kim, Tjonneland, Anne, Olsen, Anja, Boutron-Ruault, Marie-Christine, Severi, Gianluca, Fournier, Agnes, Boeing, Heiner, Trichopoulou, Antonia, Benetou, Vassiliki, Orfanos, Philippos, Masala, Giovanna, Pala, Valeria, Tumino, Rosario, Fasanelli, Francesca, Panico, Salvatore, Bueno-de-Mesquita, H Bas, Peeters, Petra, van Gils, Carla H, Quiros, J Ramon, Agudo, Antonio, Sanchez, Maria-Jose, Chirlaque, Maria-Dolores, Barricarte, Aurelio, Amiano, Pilar, Khaw, Kay-Tee, Travis, Ruth C, Dossus, Laure, Li, Kuanrong, Ferrari, Pietro, Merritt, Melissa A, Tzoulaki, Ioanna, Riboli, Elio, Kaaks, Rudolf, Husing, Anika, Fortner, Renee T, Kuhn, Tilman, Overvad, Kim, Tjonneland, Anne, Olsen, Anja, Boutron-Ruault, Marie-Christine, Severi, Gianluca, Fournier, Agnes, Boeing, Heiner, Trichopoulou, Antonia, Benetou, Vassiliki, Orfanos, Philippos, Masala, Giovanna, Pala, Valeria, Tumino, Rosario, Fasanelli, Francesca, Panico, Salvatore, Bueno-de-Mesquita, H Bas, Peeters, Petra, van Gils, Carla H, Quiros, J Ramon, Agudo, Antonio, Sanchez, Maria-Jose, Chirlaque, Maria-Dolores, Barricarte, Aurelio, Amiano, Pilar, Khaw, Kay-Tee, Travis, Ruth C, Dossus, Laure, Li, Kuanrong, Ferrari, Pietro, Merritt, Melissa A, Tzoulaki, Ioanna, Riboli, Elio, and Kaaks, Rudolf
- Published
- 2017
35. Added value of serum hormone measurements in risk prediction models for breast cancer for women not using exogenous hormones: Results from the EPIC cohort
- Author
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MS MDL 1, Epi Kanker Team 1, JC onderzoeksprogramma Kanker, Cancer, Epi Kanker Team A, Husing, Anika, Fortner, Renee T, Kuhn, Tilman, Overvad, Kim, Tjonneland, Anne, Olsen, Anja, Boutron-Ruault, Marie-Christine, Severi, Gianluca, Fournier, Agnes, Boeing, Heiner, Trichopoulou, Antonia, Benetou, Vassiliki, Orfanos, Philippos, Masala, Giovanna, Pala, Valeria, Tumino, Rosario, Fasanelli, Francesca, Panico, Salvatore, Bueno-de-Mesquita, H Bas, Peeters, Petra, van Gils, Carla H, Quiros, J Ramon, Agudo, Antonio, Sanchez, Maria-Jose, Chirlaque, Maria-Dolores, Barricarte, Aurelio, Amiano, Pilar, Khaw, Kay-Tee, Travis, Ruth C, Dossus, Laure, Li, Kuanrong, Ferrari, Pietro, Merritt, Melissa A, Tzoulaki, Ioanna, Riboli, Elio, Kaaks, Rudolf, MS MDL 1, Epi Kanker Team 1, JC onderzoeksprogramma Kanker, Cancer, Epi Kanker Team A, Husing, Anika, Fortner, Renee T, Kuhn, Tilman, Overvad, Kim, Tjonneland, Anne, Olsen, Anja, Boutron-Ruault, Marie-Christine, Severi, Gianluca, Fournier, Agnes, Boeing, Heiner, Trichopoulou, Antonia, Benetou, Vassiliki, Orfanos, Philippos, Masala, Giovanna, Pala, Valeria, Tumino, Rosario, Fasanelli, Francesca, Panico, Salvatore, Bueno-de-Mesquita, H Bas, Peeters, Petra, van Gils, Carla H, Quiros, J Ramon, Agudo, Antonio, Sanchez, Maria-Jose, Chirlaque, Maria-Dolores, Barricarte, Aurelio, Amiano, Pilar, Khaw, Kay-Tee, Travis, Ruth C, Dossus, Laure, Li, Kuanrong, Ferrari, Pietro, Merritt, Melissa A, Tzoulaki, Ioanna, Riboli, Elio, and Kaaks, Rudolf
- Published
- 2017
36. Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort
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Epi Kanker Team 1, JC onderzoeksprogramma Kanker, Cancer, Zamora-Ros, Raul, Barupal, Dinesh K., Rothwell, Joseph A., Jenab, Mazda, Fedirko, Veronika, Romieu, Isabelle, Aleksandrova, Krasimira, Overvad, Kim, Kyrø, Cecilie, Tjønneland, Anne, Affret, Aurélie, His, Mathilde, Boutron-Ruault, Marie Christine, Katzke, Verena, Kühn, Tilman, Boeing, Heiner, Trichopoulou, Antonia, Naska, Androniki, Kritikou, Maria, Saieva, Calogero, Agnoli, Claudia, Santucci de Magistris, Maria, Tumino, Rosario, Fasanelli, Francesca, Weiderpass, Elisabete, Skeie, Guri, Merino, Susana, Jakszyn, Paula, Sánchez, Maria José, Dorronsoro, Miren, Navarro, Carmen, Ardanaz, Eva, Sonestedt, Emily, Ericson, Ulrika, Maria Nilsson, Lena, Bodén, Stina, Bas Bueno-de-Mesquita, H., Peeters, Petra H., Perez-Cornago, Aurora, Wareham, Nicholas J., Khaw, Kay Thee, Freisling, Heinz, Cross, Amanda J., Riboli, Elio, Scalbert, Augustin, Epi Kanker Team 1, JC onderzoeksprogramma Kanker, Cancer, Zamora-Ros, Raul, Barupal, Dinesh K., Rothwell, Joseph A., Jenab, Mazda, Fedirko, Veronika, Romieu, Isabelle, Aleksandrova, Krasimira, Overvad, Kim, Kyrø, Cecilie, Tjønneland, Anne, Affret, Aurélie, His, Mathilde, Boutron-Ruault, Marie Christine, Katzke, Verena, Kühn, Tilman, Boeing, Heiner, Trichopoulou, Antonia, Naska, Androniki, Kritikou, Maria, Saieva, Calogero, Agnoli, Claudia, Santucci de Magistris, Maria, Tumino, Rosario, Fasanelli, Francesca, Weiderpass, Elisabete, Skeie, Guri, Merino, Susana, Jakszyn, Paula, Sánchez, Maria José, Dorronsoro, Miren, Navarro, Carmen, Ardanaz, Eva, Sonestedt, Emily, Ericson, Ulrika, Maria Nilsson, Lena, Bodén, Stina, Bas Bueno-de-Mesquita, H., Peeters, Petra H., Perez-Cornago, Aurora, Wareham, Nicholas J., Khaw, Kay Thee, Freisling, Heinz, Cross, Amanda J., Riboli, Elio, and Scalbert, Augustin
- Published
- 2017
37. Hepcidin levels and gastric cancer risk in the EPIC-EurGast study
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UMC Utrecht, MS MDL 1, Epi Kanker Team B, JC onderzoeksprogramma Kanker, Cancer, Jakszyn, Paula, Fonseca-Nunes, Ana, Lujan-Barroso, Leila, Aranda, Núria, Tous, Mónica, Arija, Victoria, Cross, Amanda J., Bueno-de-Mesquita, H. Bas, Weiderpass, Elisabete, Kühn, Tilman, Kaaks, Rudolf, Sjöberg, Klas, Ohlsson, Bodil, Tumino, Rosario, Palli, Domenico, Ricceri, Fulvio, Fasanelli, Francesca, Krogh, Vittorio, Mattiello, Amalia, Jenab, Mazda, Gunter, Marc J., Perez-Cornago, Aurora, Khaw, Kay Tee, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Trichopoulou, Antonia, Peppa, Eleni, Vasilopoulou, Effie, Boeing, Heiner, Sánchez-Cantalejo, Emilio, Huerta, José María, Dorronsoro, Miren, Barricarte, Aurelio, Quirós, José Maria, Peeters, Petra H., Agudo, Antonio, UMC Utrecht, MS MDL 1, Epi Kanker Team B, JC onderzoeksprogramma Kanker, Cancer, Jakszyn, Paula, Fonseca-Nunes, Ana, Lujan-Barroso, Leila, Aranda, Núria, Tous, Mónica, Arija, Victoria, Cross, Amanda J., Bueno-de-Mesquita, H. Bas, Weiderpass, Elisabete, Kühn, Tilman, Kaaks, Rudolf, Sjöberg, Klas, Ohlsson, Bodil, Tumino, Rosario, Palli, Domenico, Ricceri, Fulvio, Fasanelli, Francesca, Krogh, Vittorio, Mattiello, Amalia, Jenab, Mazda, Gunter, Marc J., Perez-Cornago, Aurora, Khaw, Kay Tee, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Trichopoulou, Antonia, Peppa, Eleni, Vasilopoulou, Effie, Boeing, Heiner, Sánchez-Cantalejo, Emilio, Huerta, José María, Dorronsoro, Miren, Barricarte, Aurelio, Quirós, José Maria, Peeters, Petra H., and Agudo, Antonio
- Published
- 2017
38. Impatto della non-proporzionalità dei rischi in un’analisi di mediazione su dati di sopravvivenza
- Author
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Zugna, Daniela, Fasanelli, Francesca, and Richiardi, Lorenzo
- Published
- 2016
39. L’effetto protettivo della dieta mediterranea sul tumore del colon e’ mediato dai livelli di metilazione nei geni dell’infiammazione? Uno studio caso controllo innestato nella coorte di EPIC italia
- Author
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Fasanelli, Francesca, Ricceri, Fulvio, Trevisan, Morena, Vittorio, Krogh, Valeria, Pala, Salvatore, Panico, Amalia, Mattiello, Rosario, Tumino, Maria Concetta Giurdanella, Assumma, MANUELA BIANCA, Silvia, Polidoro, and Carlotta, Sacerdote
- Published
- 2016
40. Nuovo indicatore antropometrico di obesità centrale e identificazione del rischio di mortalità generale e per cancro nella coorte Italiana di EPIC
- Author
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Vittorio, Simeon, Paolo, Chiodini, Amalia, Mattiello, Vittorio, Krogh, Valeria, Pala, Fasanelli, Francesca, Ricceri, Fulvio, Giovanna, Masala, Calogero, Saieva, Rosario, Tumino, Maria Concetta Giurdanella, and Salvatore, Panico
- Published
- 2016
41. WEIGHTING APPROACH PER MEDIATORI MULTIPLI NELL’ANALISI DI SOPRAVVIVENZA
- Author
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Fasanelli, Francesca, Giraudo, Maria Teresa, Ricceri, Fulvio, Alex, Francia, and Zugna, Daniela
- Published
- 2016
42. DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk
- Author
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Baglietto, L, Ponzi, E, Haycock, P, Hodge, A, Nullm, nullBianca Assumma, Jung, Ch, Chung, J, Fasanelli, Francesca, Guida, F, Campanella, G, Chadeau hyam, M, Grankvist, K, Johansson, M, Ala, Ugo, Provero, Paolo, Wong, Em, Joo, J, English, Dr, Kazmi, N, Lund, E, Faltus, C, Kaaks, R, Risch, A, Barrdahl, M, Sandanger, Tm, Southey, Mc, Giles, Gg, Vineis, P, Polidoro, Silvia, Relton, Cl, and Severi, G.
- Subjects
Male ,DNA methylation ,lung cancer risk ,smoking ,Medicine (all) ,Oncology ,Cancer Research ,Lung Neoplasms ,Epigenesis, Genetic ,Humans ,Genetic Predisposition to Disease ,Oncology & Carcinogenesis ,Early Detection of Cancer ,Cancer och onkologi ,DNA ,Microarray Analysis ,Cancer and Oncology ,Case-Control Studies ,Female ,ICEP ,1112 Oncology And Carcinogenesis ,Cancer Epidemiology - Abstract
DNA methylation changes are associated with cigarette smoking. We used the Illumina Infinium HumanMethylation450 array to determine whether methylation in DNA from pre‐diagnostic, peripheral blood samples is associated with lung cancer risk. We used a case‐control study nested within the EPIC‐Italy cohort and a study within the MCCS cohort as discovery sets (a total of 552 case‐control pairs). We validated the top signals in 429 case‐control pairs from another 3 studies. We identified six CpGs for which hypomethylation was associated with lung cancer risk: cg05575921 in the AHRR gene (p‐valuepooled = 4 × 10−17), cg03636183 in the F2RL3 gene (p‐valuepooled = 2 × 10 − 13), cg21566642 and cg05951221 in 2q37.1 (p‐valuepooled = 7 × 10−16 and 1 × 10−11 respectively), cg06126421 in 6p21.33 (p‐valuepooled = 2 × 10−15) and cg23387569 in 12q14.1 (p‐valuepooled = 5 × 10−7). For cg05951221 and cg23387569 the strength of association was virtually identical in never and current smokers. For all these CpGs except for cg23387569, the methylation levels were different across smoking categories in controls (p‐valuesheterogeneity ≤ 1.8 x10 − 7), were lowest for current smokers and increased with time since quitting for former smokers. We observed a gain in discrimination between cases and controls measured by the area under the ROC curve of at least 8% (p‐values ≥ 0.003) in former smokers by adding methylation at the 6 CpGs into risk prediction models including smoking status and number of pack‐years. Our findings provide convincing evidence that smoking and possibly other factors lead to DNA methylation changes measurable in peripheral blood that may improve prediction of lung cancer risk., What's new? It is well known that smoking can cause lung cancer but the concept that it might do so by changing DNA methylation is only emerging. Here the authors identify six sites of methylation (CpGs), where methylation levels were associated with lung cancer risk after adjusting for smoking, current or former. Methylation of five of the CpGs was lowest in current smokers and increased in former smokers with time since quitting, supporting the growing evidence that smoking may lead to DNA methylation changes measurable in peripheral blood and useful as predictive markers for lung cancer risk, especially in former smokers.
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- 2016
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43. Analisi di mediazione per l’associazione tra livello di istruzione, markers infiammatori e malattie cardiovascolari: risultati dallo studio EPIC-Italia
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Giraudo, Maria Teresa, Ricceri, Fulvio, Fasanelli, Francesca, Carlotta, Sacerdote, Angelo, D'Errico, Meena, Kumari, Claudia, Agnoli, Sabina, Sieri, Giovanna, Masala, Saverio, Caini, Rosario, Tumino, Graziella, Frasca, Licia, Iacoviello, Amalia, Mattiello, and Salvatore P. A. N. I. C., O.
- Published
- 2016
44. Diet Quality Scores and Prediction of All-Cause, Cardiovascular and Cancer Mortality in a Pan-European Cohort Study
- Author
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Lassale, Camille Gunter, Marc J. Romaguera, Dora Peelen, Linda M. Van der Schouw, Yvonne T. Beulens, Joline W. J. and Freisling, Heinz Muller, David C. Ferrari, Pietro and Huybrechts, Inge Fagherazzi, Guy Boutron-Ruault, Marie-Christine and Affret, Aurelie Overvad, Kim Dahm, Christina C. Olsen, Anja Roswall, Nina Tsilidis, Konstantinos K. Katzke, Verena A. Kuehn, Tilman Buijsse, Brian Quiros, Jose-Ramon and Sanchez-Cantalejo, Emilio Etxezarreta, Nerea Maria Huerta, Jose and Barricarte, Aurelio Bonet, Catalina Khaw, Kay-Tee Key, Timothy J. Trichopoulou, Antonia Bamia, Christina Lagiou, Pagona Palli, Domenico Agnoli, Claudia Tumino, Rosario and Fasanelli, Francesca Panico, Salvatore Bueno-de-Mesquita, H. Bas and Boer, Jolanda M. A. Sonestedt, Emily Nilsson, Lena Maria and Renstrom, Frida Weiderpass, Elisabete Skeie, Guri Lund, Eiliv Moons, Karel G. M. Riboli, Elio Tzoulaki, Ioanna
- Abstract
Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective Investigation into Cancer and Nutrition, followed-up for a median of 12.8y. All dietary scores studied showed significant inverse associations with all outcomes. The range of HRs (95% CI) in the top vs. lowest quartile of dietary scores in a composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity and study centre) was 0.75 (0.72-0.79) to 0.88 (0.84-0.92) for all-cause, 0.76 (0.69-0.83) to 0.84 (0.76-0.92) for CVD and 0.78 (0.73-0.83) to 0.91 (0.85-0.97) for cancer mortality. Models with dietary scores alone showed low discrimination, but composite models also including age, sex and other non-invasive factors showed good discrimination and calibration, which varied little between different diet scores examined. Mean C-statistic of full models was 0.73, 0.80 and 0.71 for all-cause, CVD and cancer mortality. Dietary scores have poor predictive performance for 10-year mortality risk when used in isolation but display good predictive ability in combination with other non-invasive common risk factors.
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- 2016
45. L’associazione tra tumore della vescica e esposizioni professionali: analisi pooled di due studi casocontrollo italiani
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Sciannameo, Veronica, Angela, Carta, Angelo, D’Errico, Giraudo, Maria Teresa, Fasanelli, Francesca, Cecilia, Arici, Maule, MILENA MARIA, Paolo, Destefanis, Rolle, Luigi, Gontero, Paolo, Giovanni, Casetta, Andrea, Zitella, Giuseppina, Cucchiarale, Paolo, Vineis, Stefano, Porru, Carlotta, Sacerdote, and Ricceri, Fulvio
- Published
- 2016
46. Increased correlation between methylation sites in epigenome-wide replication studies: impact on analysis and results
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Popovic, Maja, primary, Fasanelli, Francesca, additional, Fiano, Valentina, additional, Biggeri, Annibale, additional, and Richiardi, Lorenzo, additional
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- 2017
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47. Diet and endometrial cancer: a focus on the role of fruit and vegetable intake, Mediterranean diet and dietary inflammatory index in the endometrial cancer risk
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Ricceri, Fulvio, primary, Giraudo, Maria Teresa, additional, Fasanelli, Francesca, additional, Milanese, Dario, additional, Sciannameo, Veronica, additional, Fiorini, Laura, additional, and Sacerdote, Carlotta, additional
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- 2017
- Full Text
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48. Added Value of Serum Hormone Measurements in Risk Prediction Models for Breast Cancer for Women Not Using Exogenous Hormones: Results from the EPIC Cohort
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Hüsing, Anika, primary, Fortner, Renée T., additional, Kühn, Tilman, additional, Overvad, Kim, additional, Tjønneland, Anne, additional, Olsen, Anja, additional, Boutron-Ruault, Marie-Christine, additional, Severi, Gianluca, additional, Fournier, Agnes, additional, Boeing, Heiner, additional, Trichopoulou, Antonia, additional, Benetou, Vassiliki, additional, Orfanos, Philippos, additional, Masala, Giovanna, additional, Pala, Valeria, additional, Tumino, Rosario, additional, Fasanelli, Francesca, additional, Panico, Salvatore, additional, Bueno de Mesquita, H. Bas, additional, Peeters, Petra H., additional, van Gills, Carla H., additional, Quirós, J. Ramón, additional, Agudo, Antonio, additional, Sánchez, Maria-Jose, additional, Chirlaque, Maria-Dolores, additional, Barricarte, Aurelio, additional, Amiano, Pilar, additional, Khaw, Kay-Tee, additional, Travis, Ruth C., additional, Dossus, Laure, additional, Li, Kuanrong, additional, Ferrari, Pietro, additional, Merritt, Melissa A., additional, Tzoulaki, Ioanna, additional, Riboli, Elio, additional, and Kaaks, Rudolf, additional
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- 2017
- Full Text
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49. Abdominal adiposity is not a mediator of the protective effect of Mediterranean diet on colorectal cancer
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Fasanelli, Francesca, primary, Zugna, Daniela, additional, Giraudo, Maria Teresa, additional, Krogh, Vittorio, additional, Grioni, Sara, additional, Panico, Salvatore, additional, Mattiello, Amalia, additional, Masala, Giovanna, additional, Caini, Saverio, additional, Tumino, Rosario, additional, Frasca, Graziella, additional, Sciannameo, Veronica, additional, Ricceri, Fulvio, additional, and Sacerdote, Carlotta, additional
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- 2017
- Full Text
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50. Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort
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Zamora‐Ros, Raul, primary, Barupal, Dinesh K., additional, Rothwell, Joseph A., additional, Jenab, Mazda, additional, Fedirko, Veronika, additional, Romieu, Isabelle, additional, Aleksandrova, Krasimira, additional, Overvad, Kim, additional, Kyrø, Cecilie, additional, Tjønneland, Anne, additional, Affret, Aurélie, additional, His, Mathilde, additional, Boutron‐Ruault, Marie‐Christine, additional, Katzke, Verena, additional, Kühn, Tilman, additional, Boeing, Heiner, additional, Trichopoulou, Antonia, additional, Naska, Androniki, additional, Kritikou, Maria, additional, Saieva, Calogero, additional, Agnoli, Claudia, additional, Santucci de Magistris, Maria, additional, Tumino, Rosario, additional, Fasanelli, Francesca, additional, Weiderpass, Elisabete, additional, Skeie, Guri, additional, Merino, Susana, additional, Jakszyn, Paula, additional, Sánchez, Maria‐José, additional, Dorronsoro, Miren, additional, Navarro, Carmen, additional, Ardanaz, Eva, additional, Sonestedt, Emily, additional, Ericson, Ulrika, additional, Maria Nilsson, Lena, additional, Bodén, Stina, additional, Bueno‐de‐Mesquita, H. B(as), additional, Peeters, Petra H., additional, Perez‐Cornago, Aurora, additional, Wareham, Nicholas J., additional, Khaw, Kay‐Thee, additional, Freisling, Heinz, additional, Cross, Amanda J., additional, Riboli, Elio, additional, and Scalbert, Augustin, additional
- Published
- 2017
- Full Text
- View/download PDF
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