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The purpose of this study was to investigate Tennessee principals' selection of physical education teacher applicants based on hypothetical descriptions of academic merit and physical appearance. A final sample of 139 of the 210 randomly selected school principals completed the survey, "Hiring the Physical Education Teacher." Results indicated that significantly overweight (20 pounds above ideal weight) candidates were more likely to be eliminated from the applicant pool than slightly overweight (10 pounds above ideal weight) candidates (t [138] = 14.5, p less than 0.05). Further, binomial analyses revealed statistically significant differences (p less than 0.01) between candidates when academic ranking was added as a descriptor. Specifically, an average GPA, slightly overweight candidate was more favored for the job than a below average GPA, good physical condition counterpart. Also, a significantly overweight applicant with an above average GPA was less favored for hiring when compared to an average GPA candidate with good physical condition. Overall, physical description/appearance influenced Tennessee principal's selections in hiring physical education teachers. (Contains 2 tables.)

Regimens containing abacavir (ABC), tenofovir (TDF), and lamivudine (3TC) have recently been demonstrated to have high failure rates. This poses a clinical dilemma of how to manage patients currently being treated with other regimens containing tenofovir/abacavir. We evaluated the outcomes of tenofovir/abacavir regimens in our clinical practice through a retrospective review of 2655 charts. Two hundred patients (7%) were on a tenofovir/abacavircontaining regimen. Fifty-nine patients met the criteria for analysis and were grouped into three groups: (1) antiretroviral naive, (2) virally suppressed patients switched to TDF/ABC, and (3) patients with failure of their first antiretroviral regimen. Rates of viral suppression in the naive, switch, and first-failure groups were 95%, 86%, and 46%, respectively. In the first-failure group, viral suppression was 66% without and 18% with a preexisting M184V. A composite analysis of the groups revealed a success rate of 86% when the regimen contained zidovudine (ZDV) and 62% when it did not. No K65R mutations were noted. These findings support continued caution in the use of TDF/ABC in combination. However, these data suggest that this combination may be successfully used in selected situations such as in combination with ZDV. In patients already virally suppressed on a TDF/ABC-containing regimen, considerations include continuing the regimen or adding zidovudine, in the attempt to protect against the development of a K65R mutation and/or virologic failure, versus changing a stable regimen.

Research has been conducted on serologic techniques for recent HIV-1 infection classification. The development of sensitive/less sensitive test strategy which includes an assay for rapid identification of people with recent infection followe d by an enzyme immunoassay with exquisite specificity is described.

A sensitive/less sensitive testing strategy may effectively identify patients with early HIV infection. Early HIV infection describes the period soon after HIV antibodies become detectable in the blood. Researchers tested a large number of HIV patients, AIDS patients, and blood donors for immune markers of infection. The new testing strategy correctly identified 95% of patients with early HIV infection. Identification of these patients facilitates their enrollment in studies of the development and progression of HIV.

A sensitive/less sensitive testing strategy may effectively identify patients with early HIV infection. Early HIV infection describes the period soon after HIV antibodies become detectable in the blood. Researchers tested a large number of HIV patients, AIDS patients, and blood donors for immune markers of infection. The new testing strategy correctly identified 95% of patients with early HIV infection. Identification of these patients facilitates their enrollment in studies of the development and progression of HIV.

A sensitive/less sensitive testing strategy may effectively identify patients with early HIV infection. Early HIV infection describes the period soon after HIV antibodies become detectable in the blood. Researchers tested a large number of HIV patients, AIDS patients, and blood donors for immune markers of infection. The new testing strategy correctly identified 95% of patients with early HIV infection. Identification of these patients facilitates their enrollment in studies of the development and progression of HIV.

A sensitive/less sensitive testing strategy may effectively identify patients with early HIV infection. Early HIV infection describes the period soon after HIV antibodies become detectable in the blood. Researchers tested a large number of HIV patients, AIDS patients, and blood donors for immune markers of infection. The new testing strategy correctly identified 95% of patients with early HIV infection. Identification of these patients facilitates their enrollment in studies of the development and progression of HIV.

Este estudo buscou ampliar o conhecimento sobre os desafios, as oportunidades e os contextos da gestão ambiental municipal em Minas Gerais. Através de um questionário on-line enviado a contatos de 760 municípios, obteve-se 88 respostas válidas. Os dados foram analisados através do uso de estatística descritiva e inferencial. Dentre os resultados alcançados destacam-se: (i) os desafios e oportunidades relacionados à gestão dos resíduos sólidos urbanos são centrais e se retroalimentam negativamente pela falta de pessoal, de recursos e de projetos; (ii) há um cenário favorável à restauração ecológica e à economia circular nos municípios, que não é realizado devido à baixa capacidade institucional; (iii) as unidades de conservação (UCs) municipais foram mais frequentes que as UCs federais e as estaduais, um dado positivo, mas que alerta para a subnotificação de UCs municipais no cadastro nacional e para a necessidade de pesquisas e esforços que integrem os municípios ao contexto dos territórios especialmente protegidos; (iv) 68% dos municípios amostrados recebiam, no momento da amostragem entre ago-2018 e ago-2019, ICMS Ecológico, o que deve estar relacionado à frequência observada de UCs nos municípios; (v) 60% dos municípios têm algum tipo de norma ambiental própria e isto independe do tamanho populacional e da realização de licenciamento ambiental de empreendimentos de impacto local; (vi) a intersetorialidade é praticada entre as instâncias ambientais municipais e as estaduais, o que pode estar relacionado a procedimentos padrão, como o do ICMS Ecológico; (vii) os conselhos municipais de meio ambiente foram apontados como o principal instrumento de gestão, remetendo à importância da democracia para a gestão ambiental; (viii) um terço dos gestores amostrados não compreendem bem o contexto dos ODS (Objetivos do Desenvolvimento Sustentável); (ix) parcerias entre a gestão ambiental municipal e as universidades presentes nos territórios são um potencial a ser impulsionado. Recomenda-se que as instituições de pesquisa, inovação e empreendedorismo tenham atenção e um olhar mais direcionado para as oportunidades socioambientais presentes nos municípios menores e interioranos.

In A Priori Justification, Albert Casullo argues that extant attempts to explicate experiential justification--by stipulation, introspection, conceptual analysis, thought experimentation, and/or appeal to intuitions about hypothetical cases--are unsuccessful. He draws the following conclusion: "armchair methods" such as these are inadequate to the task. Instead, empirical methods should be used to investigate the distinction between experiential and non-experiential justification and to address questions concerning the nature, extent, and existence of the a priori. In this essay, I show that Casullo has not refuted armchair explications of experiential justification, in particular those that appeal to introspectively accessible phenomenology. I do this by presenting a phenomenal theory of experiential justification that (a) has a significant degree of initial plausibility and (b) survives Casullo's general attack on such theories. As a result, a premise in the central argument for Casullo's signature proposal concerning the a priori is undermined. [ABSTRACT FROM AUTHOR]