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162 results on '"Farinotti, Mariangela"'

1. The role of adjuvant chemotherapy in patients with H3K27 altered diffuse midline gliomas: a multicentric retrospective study

Author

Di Nunno, Vincenzo, Lombardi, Giuseppe, Simonelli, Matteo, Minniti, Giuseppe, Mastronuzzi, Angela, Di Ruscio, Valentina, Corrà, Martina, Padovan, Marta, Maccari, Marta, Caccese, Mario, Simonetti, Giorgia, Berlendis, Arianna, Farinotti, Mariangela, Pollo, Bianca, Antonelli, Manila, Di Muzio, Antonio, Dipasquale, Angelo, Asioli, Sofia, De Biase, Dario, Tosoni, Alicia, Silvani, Antonio, and Franceschi, Enrico

Published
2024
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3. Italian cross-cultural adaptation of the Quality of Communication questionnaire and the 4-item advance care planning engagement questionnaire

Author

De Panfilis, Ludovica, Veronese, Simone, Perin, Marta, Cascioli, Marta, Farinotti, Mariangela, Kruger, Paola, Zagarella, Roberta M, Curtis, JR, Sudore, Rebecca L, Nielsen, Elizabeth L, Engelberg, Ruth A, Giordano, Andrea, Solari, Alessandra, and project, on behalf of the ConCure-SM

Subjects
Health Services and Systems, Biomedical and Clinical Sciences, Clinical Sciences, Health Sciences, Clinical Research, Humans, Cross-Cultural Comparison, Communication, Advance Care Planning, Surveys and Questionnaires, Italy, Psychometrics, ConCure-SM project, General Science & Technology
Abstract

BackgroundAdvance care planning (ACP) is influenced by several factors (e.g., patient's readiness to engage, clinician's skills, and the cultural environment). Availability of reliable and valid self-reported measures of the ACP domains is crucial, including cross-cultural equivalence.AimTo culturally adapt into Italian the 19-item Quality of Communication (QOC) and the 4-item ACP Engagement (4-item ACP-E) questionnaires.MethodsWe translated and culturally adapted the two questionnaires and produced a significant other (SO) version of the QOC (QOC-SO). Each questionnaire was field tested via cognitive interviews with users: nine patients (QOC, 4-item ACP-E) and three SOs (QOC-SO) enrolled at three palliative care services.ResultsWe made minor changes to 5/19 QOC items, to improve clarity and internal consistency; we changed the response option 'didn't do' into 'not applicable'. Finally, we slightly revised the QOC to adapt it to the paper/electronic format. QOC debriefing revealed that the section on end of life was emotionally challenging for both patients and SOs. We simplified the 4-item ACP-E layout, added a sentence in the introduction, and revised the wording of one item, to improve coherence with the Italian ACP legislation. ACP-E debriefing did not reveal any major issue.ConclusionsResults were satisfactory in terms of semantic, conceptual and normative equivalence of both questionnaires. Acceptability was satisfactory for the 4-item ACP-E, while findings of the QOC cognitive debriefing informed a major amendment of a pilot trial protocol on ACP in multiple sclerosis (ConCure-SM): use of the interviewer version only, in an adaptive form. Psychometric testing of both questionnaires on a large, independent sample will follow.

Published
2023

6. Clinicopathological and molecular landscape of 5-year IDH-wild-type glioblastoma survivors: A multicentric retrospective study

Author

Miele, Evelina, Anghileri, Elena, Calatozzolo, Chiara, Lazzarini, Elisabetta, Patrizi, Sara, Ciolfi, Andrea, Pedace, Lucia, Patanè, Monica, Abballe, Luana, Paterra, Rosina, Maddaloni, Luisa, Barresi, Sabina, Mastronuzzi, Angela, Petruzzi, Alessandra, Tramacere, Irene, Farinotti, Mariangela, Gurrieri, Lorena, Pirola, Elena, Scarpelli, Mauro, Lombardi, Giuseppe, Villani, Veronica, Simonelli, Matteo, Merli, Rossella, Salmaggi, Andrea, Tartaglia, Marco, Silvani, Antonio, DiMeco, Francesco, Calistri, Daniele, Lamperti, Elena, Locatelli, Franco, Indraccolo, Stefano, and Pollo, Bianca

Published
2024
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9. Diagnosis and treatment of Chiari malformation type 1 in children: the International Consensus Document

Author

Massimi, Luca, Peretta, Paola, Erbetta, Alessandra, Solari, Alessandra, Farinotti, Mariangela, Ciaramitaro, Palma, Saletti, Veronica, Caldarelli, Massimo, Canheu, Alexandre Casagrande, Celada, Carlo, Chiapparini, Luisa, Chieffo, Daniela, Cinalli, Giuseppe, Di Rocco, Federico, Furlanetto, Marika, Giordano, Flavio, Jallo, George, James, Syril, Lanteri, Paola, Lemarchand, Christian, Messing-Jünger, Martina, Parazzini, Cecilia, Paternoster, Giovanna, Piatelli, Gianluca, Poca, Maria. A., Prabahkar, Prab, Ricci, Federica, Righini, Andrea, Sala, Francesco, Sahuquillo, Juan, Stoodley, Marcus, Talamonti, Giuseppe, Thompson, Dominic, Triulzi, Fabio, Zucchelli, Mino, and Valentini, Laura

Published
2022
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10. Diagnosis and treatment of Chiari malformation and syringomyelia in adults: international consensus document

Author

Ciaramitaro, Palma, Massimi, Luca, Bertuccio, Alessandro, Solari, Alessandra, Farinotti, Mariangela, Peretta, Paola, Saletti, Veronica, Chiapparini, Luisa, Barbanera, Andrea, Garbossa, Diego, Bolognese, Paolo, Brodbelt, Andrew, Celada, Carlo, Cocito, Dario, Curone, Marcella, Devigili, Grazia, Erbetta, Alessandra, Ferraris, Marilena, Furlanetto, Marika, Gilanton, Mado, Jallo, George, Karadjova, Marieta, Klekamp, Jorg, Massaro, Fulvio, Morar, Sylvia, Parker, Fabrice, Perrini, Paolo, Poca, Maria Antonia, Sahuquillo, Juan, Stoodley, Marcus, Talamonti, Giuseppe, Triulzi, Fabio, Valentini, Maria Consuelo, Visocchi, Massimiliano, and Valentini, Laura

Published
2022
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13. Medulloblastoma of the adult: results from a multicenter retrospective study by AINO (Italian Association of Neuro-Oncology) and SIN (Italian Society of Neurology)

Author

Gaviani, Paola, Simonetti, Giorgia, Rudà, Roberta, Franchino, Federica, Lombardi, Giuseppe, Possanzini, Marco, Squintu, Sara, Villani, Veronica, Teriaca, Mariaausilia, Cavallieri, Francesco, Caffo, Maria, Salmaggi, Andrea, Bianco, Andrea, Anghileri, Elena, Farinotti, Mariangela, Tramacere, Irene, and Silvani, Antonio

Published
2021
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14. Development of A Radiomic Model for MGMT Promoter Methylation Detection in Glioblastoma Using Conventional MRI

Author

Doniselli, Fabio M., primary, Pascuzzo, Riccardo, additional, Agrò, Massimiliano, additional, Aquino, Domenico, additional, Anghileri, Elena, additional, Farinotti, Mariangela, additional, Pollo, Bianca, additional, Paterra, Rosina, additional, Cuccarini, Valeria, additional, Moscatelli, Marco, additional, DiMeco, Francesco, additional, and Sconfienza, Luca Maria, additional

Published
2023
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16. Correction to: Diagnosis and treatment of Chiari Malformation and syringomyelia in adults: International Consensus Document

Author

Ciaramitaro, Palma, Massimi, Luca, Bertuccio, Alessandro, Solari, Alessandra, Farinotti, Mariangela, Peretta, Paola, Saletti, Veronica, Chiapparini, Luisa, Barbanera, Andrea, Garbossa, Diego, Bolognese, Paolo, Brodbelt, Andrew, Celada, Carlo, Cocito, Dario, Curone, Marcella, Devigili, Grazia, Erbetta, Alessandra, Ferraris, Marilena, Furlanetto, Marika, Gilanton, Mado, Jallo, George, Karadjova, Marieta, Klekamp, Jorg, Massaro, Fulvio, Morar, Sylvia, Parker, Fabrice, Perrini, Paolo, Poca, Maria Antonia, Sahuquillo, Juan, Stoodley, Marcus, Talamonti, Giuseppe, Triulzi, Fabio, Valentini, Maria Consuelo, Visocchi, Massimiliano, and Valentini, Laura

Published
2022
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17. User appraisal of a booklet for advance care planning in multiple sclerosis: a multicenter, qualitative Italian study

Author

Giordano, Andrea, primary, De Panfilis, Ludovica, additional, Veronese, Simone, additional, Bruzzone, Michela, additional, Cascioli, Marta, additional, Farinotti, Mariangela, additional, Giovannetti, Ambra Mara, additional, Grasso, Maria Grazia, additional, Kruger, Paola, additional, Lugaresi, Alessandra, additional, Manson, Leigh, additional, Perin, Marta, additional, Pucci, Eugenio, additional, Solaro, Claudio, additional, Ghirotto, Luca, additional, and Solari, Alessandra, additional

Published
2023
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18. Development of A Radiomic Model for MGMT Promoter Methylation Detection in Glioblastoma Using Conventional MRI.

Author

Doniselli, Fabio M., Pascuzzo, Riccardo, Agrò, Massimiliano, Aquino, Domenico, Anghileri, Elena, Farinotti, Mariangela, Pollo, Bianca, Paterra, Rosina, Cuccarini, Valeria, Moscatelli, Marco, DiMeco, Francesco, and Sconfienza, Luca Maria

Subjects
METHYLGUANINE, MACHINE learning, O6-Methylguanine-DNA Methyltransferase, METHYLATION, GLIOBLASTOMA multiforme, MAGNETIC resonance imaging, SUPPORT vector machines
Abstract

The methylation of the O6-methylguanine-DNA methyltransferase (MGMT) promoter is a molecular marker associated with a better response to chemotherapy in patients with glioblastoma (GB). Standard pre-operative magnetic resonance imaging (MRI) analysis is not adequate to detect MGMT promoter methylation. This study aims to evaluate whether the radiomic features extracted from multiple tumor subregions using multiparametric MRI can predict MGMT promoter methylation status in GB patients. This retrospective single-institution study included a cohort of 277 GB patients whose 3D post-contrast T1-weighted images and 3D fluid-attenuated inversion recovery (FLAIR) images were acquired using two MRI scanners. Three separate regions of interest (ROIs) showing tumor enhancement, necrosis, and FLAIR hyperintensities were manually segmented for each patient. Two machine learning algorithms (support vector machine (SVM) and random forest) were built for MGMT promoter methylation prediction from a training cohort (196 patients) and tested on a separate validation cohort (81 patients), based on a set of automatically selected radiomic features, with and without demographic variables (i.e., patients' age and sex). In the training set, SVM based on the selected radiomic features of the three separate ROIs achieved the best performances, with an average of 83.0% (standard deviation: 5.7%) for accuracy and 0.894 (0.056) for the area under the curve (AUC) computed through cross-validation. In the test set, all classification performances dropped: the best was obtained by SVM based on the selected features extracted from the whole tumor lesion constructed by merging the three ROIs, with 64.2% (95% confidence interval: 52.8–74.6%) accuracy and 0.572 (0.439–0.705) for AUC. The performances did not change when the patients' age and sex were included with the radiomic features into the models. Our study confirms the presence of a subtle association between imaging characteristics and MGMT promoter methylation status. However, further verification of the strength of this association is needed, as the low diagnostic performance obtained in this validation cohort is not sufficiently robust to allow clinically meaningful predictions. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Table S5 from Tau Mutations Serve as a Novel Risk Factor for Cancer

Author

Rossi, Giacomina, primary, Redaelli, Veronica, primary, Contiero, Paolo, primary, Fabiano, Sabrina, primary, Tagliabue, Giovanna, primary, Perego, Paola, primary, Benussi, Luisa, primary, Bruni, Amalia C., primary, Filippini, Graziella, primary, Farinotti, Mariangela, primary, Giaccone, Giorgio, primary, Buiatiotis, Simona, primary, Manzoni, Claudia, primary, Ferrari, Raffaele, primary, and Tagliavini, Fabrizio, primary

Published
2023
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21. Data from Tau Mutations Serve as a Novel Risk Factor for Cancer

Author

Rossi, Giacomina, primary, Redaelli, Veronica, primary, Contiero, Paolo, primary, Fabiano, Sabrina, primary, Tagliabue, Giovanna, primary, Perego, Paola, primary, Benussi, Luisa, primary, Bruni, Amalia C., primary, Filippini, Graziella, primary, Farinotti, Mariangela, primary, Giaccone, Giorgio, primary, Buiatiotis, Simona, primary, Manzoni, Claudia, primary, Ferrari, Raffaele, primary, and Tagliavini, Fabrizio, primary

Published
2023
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22. Towards an Established Intraoperative Oncological Favorable Tool: Results of Fluorescein-Guided Resection from a Monocentric, Prospective Series of 93 Primary Glioblastoma Patients

Author

Falco, Jacopo, primary, Rubiu, Emanuele, additional, Broggi, Morgan, additional, Farinotti, Mariangela, additional, Vetrano, Ignazio G., additional, Schiariti, Marco, additional, Anghileri, Elena, additional, Eoli, Marica, additional, Pollo, Bianca, additional, Moscatelli, Marco, additional, Restelli, Francesco, additional, Mazzapicchi, Elio, additional, La Corte, Emanuele, additional, Bonomo, Giulio, additional, Gemma, Marco, additional, Broggi, Giovanni, additional, Ferroli, Paolo, additional, and Acerbi, Francesco, additional

Published
2022
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25. Towards an Established Intraoperative Oncological Favorable Tool: Results of Fluorescein-Guided Resection from a Monocentric, Prospective Series of 93 Primary Glioblastoma Patients.

Author

Falco, Jacopo, Rubiu, Emanuele, Broggi, Morgan, Farinotti, Mariangela, Vetrano, Ignazio G., Schiariti, Marco, Anghileri, Elena, Eoli, Marica, Pollo, Bianca, Moscatelli, Marco, Restelli, Francesco, Mazzapicchi, Elio, La Corte, Emanuele, Bonomo, Giulio, Gemma, Marco, Broggi, Giovanni, Ferroli, Paolo, and Acerbi, Francesco

Subjects
GLIOBLASTOMA multiforme, PROGRESSION-free survival, OVERALL survival, BLOOD-brain barrier
Abstract

It is commonly reported that maximizing surgical resection of contrast-enhancing regions in patients with glioblastoma improves overall survival. Efforts to achieve an improved rate of resection have included several tools: among those, the recent widespread of fluorophores. Sodium fluorescein is an unspecific, vascular dye which tends to accumulate in areas with an altered blood–brain barrier. In this retrospective analysis of patients prospectively enrolled in the FLUOCERTUM study, we aimed to assess the role of fluorescein-guided surgery on surgical radicality, survival, and morbidity. A retrospective review based on 93 consecutively and prospectively enrolled IDH wild-type glioblastoma patients (2016–2022) was performed; fluorescence characteristics, rate of resection, clinical outcome, and survival were analyzed. No side effect related to fluorescein occurred; all of the tumors presented a strong yellow-green enhancement and fluorescein was judged fundamental in distinguishing tumors from viable tissue in all cases. Gross total resection was achieved in 77 cases out of 93 patients (82.8%). After a mean follow-up time of 17.4 months (3–78 months), the median progression-free survival was 12 months, with a PFS-6 and PFS-12 of 94.2% and 50%, respectively, whereas median overall survival was estimated to be 16 months; survival at 6, 12, and 24 months was 91.8%, 72.3%, and 30.1%, respectively. Based on these results, we can assert that the fluorescein-guided technique is a safe and valuable method for patients harboring a newly diagnosed, untreated glioblastoma. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Diagnosis and treatment of Chiari malformation type 1 in children : the International Consensus Document

Author

Massimi, Luca, Peretta, Paola, Erbetta, Alessandra, Solari, Alessandra, Farinotti, Mariangela, Ciaramitaro, Palma, Saletti, Veronica, Caldarelli, Massimo, Canheu, Alexandre Casagrande, Celada, Carlo, Chiapparini, Luisa, Chieffo, Daniela, Cinalli, Giuseppe, Di Rocco, Federico, Furlanetto, Marika, Giordano, Flavio, Jallo, George, James, Syril, Lanteri, Paola, Lemarchand, Christian, Messing-Jünger, Martina, Parazzini, Cecilia, Paternoster, Giovanna, Piatelli, Gianluca, Poca Pastor, María Antonia, Prabahkar, Prab, Ricci, Federica, Righini, Andrea, Sala, Francesco, Sahuquillo Barris, Juan, Stoodley, Marcus, Talamonti, Giuseppe, Thompson, Dominic, Triulzi, Fabio, Zucchelli, Mino, Valentini, Laura, Universitat Autònoma de Barcelona, Institut Català de la Salut, [Massimi L] Pediatric Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy. [Peretta P] Pediatric Neurosurgery, AOU Citta’ della Salute e della Scienza di Torino, Torino, Italy. [Erbetta A] Department of Neuroradiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy. [Solari A, Farinotti M] Neuroepidemiology Unit – Scientific Directorate, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy. [Ciaramitaro P] Department of Neuroscience, AOU Citta’ della Salute e della Scienza di Torino, Torino, Italy. [Poca MA, Sahuquillo J] Unitat de Recerca en Neurotrauma i Neurocirurgia, Servei de Neurocirurgia i Neurocirurgia Pediàtrica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain, and Vall d'Hebron Barcelona Hospital Campus

Subjects
medicine.medical_specialty, Consensus, Delphi Technique, Statement (logic), Craniovertebral decompression, education, Delphi method, personas::Grupos de Edad::niño [DENOMINACIONES DE GRUPOS], Dermatology, Nervous System Diseases::Nervous System Malformations::Neural Tube Defects::Arnold-Chiari Malformation [DISEASES], Malalties - Presa de decisions, Likert scale, 03 medical and health sciences, 0302 clinical medicine, Diagnòstic, enfermedades del sistema nervioso::malformaciones del sistema nervioso::defectos del tubo neural::malformación de Arnold-Chiari [ENFERMEDADES], medicine, Humans, Chiari 1 malformation, Child, Children, Otros calificadores::/terapia [Otros calificadores], Chiari malformation, International network, Consensus conference, Other subheadings::/therapy [Other subheadings], General Medicine, Persons::Age Groups::Child [NAMED GROUPS], medicine.disease, Syringomyelia, Arnold-Chiari Malformation, Management, Psychiatry and Mental health, Patient population, Ciencias de la información::análisis de sistemas::técnica Delfos [CIENCIA DE LA INFORMACIÓN], Italy, Tub neural - Malformacions, 030220 oncology & carcinogenesis, Family medicine, Information Science::Systems Analysis::Delphi Technique [INFORMATION SCIENCE], Original Article, Neurology (clinical), Psychology, Delphi round, 030217 neurology & neurosurgery
Abstract

Background Chiari malformation type 1 (CM1) is a rare condition where agreed classification and treatment are still missing. The goal of this study is to achieve a consensus on the diagnosis and treatment of CM1 in children. Methods A multidisciplinary panel formulated 57 provisional statements based on a review of the literature. Thirty-four international experts (IE) participated in a Delphi study by independently rating each statement on a 4-point Likert scale (“strongly disagree,” “disagree,” “agree,” “strongly agree”). Statements that were endorsed (“agree” or “strongly agree”) by < 75% of raters were re-formulated, or new statements were added, and another Delphi round followed (up to a maximum of three). Results Thirty-five IE were contacted and 34 agreed to participate. A consensus was reached on 30/57 statements (52.6%) after round 1. Three statements were added, and one removed. After round 2, agreement was reached on 56/59 statements (94.9%). Finally, after round 3, which took place during the 2019 Chiari Consensus Conference (Milan, Italy), agreement was reached on 58/59 statements (98.3%) about four main sections (Definition and Classification, Planning, Surgery, Isolated Syringomyelia). Only one statement did not gain a consensus, which is the “definition of radiological failure 24 month post-surgery.” Conclusions The consensus document consists of 58 statements (24 on diagnosis, 34 on treatment), serving clinicians and researchers following children with CM1. There is a clear need for establishing an international network and registry and to promote collaborative studies to increase the evidence base and optimize the long-term care of this patient population.

Published
2021

29. Exposure to medical radiation during fetal life, childhood and adolescence and risk of brain tumor in young age: results from the MOBI-Kids Case-Control Study

Author

Pasqual, Elisa, Castanõ-Vinyals, Gemma, Thierry-Chef, Isabelle, Kojimahara, Noriko, Sim, Malcolm R., Kundi, Michael, Krewski, Daniel, Momoli, Franco, Lacour, Brigitte, Remen, Thomas, Radon, Katja, Weinmann, Tobias, Petridou, Eleni, Moschovi, Maria, Dikshit, Rajesh, Sadetski, Siegal, Maule, Milena, Farinotti, Mariangela, Ha, Mina, T'Mannetje, Andrea, Alguacil, Juan, Aragonés, Nuria, Vermeulen, Roel, Kromhout, Hans, Cardis, Elisabeth, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, IRAS OH Epidemiology Chemical Agents, and dIRAS RA-2

Subjects
Adult, Male, Pediatrics, medicine.medical_specialty, Infants -- Malalties, Neoplasms, Radiation-Induced, Children-adolescent health, Adolescent, Epidemiology, Brain tumor, Clinical Neurology, Radiation Dosage, Brain cancer, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Pregnancy, Radiologia mèdica, Cervell -- Tumors, medicine, Humans, Environmental exposure, Epidemiology studies, Medical radiation, Child, Adolescents -- Malalties, Fetus, business.industry, Brain Neoplasms, Fetus -- Malalties, Confounding, Case-control study, Environmental Exposure, medicine.disease, Magnetic Resonance Imaging, 3. Good health, Radiography, 030220 oncology & carcinogenesis, Radiological weapon, Case-Control Studies, Prenatal Exposure Delayed Effects, Female, Neurology (clinical), business
Abstract

Background: We explored the association between ionizing radiation (IR) from pre-natal and post-natal radio-diagnostic procedures and brain cancer risk within the MOBI-kids study. Methods: MOBI-kids is an international (Australia, Austria, Canada, France, Germany, Greece, India, Israel, Italy, Japan, Korea, New Zealand, Spain, The Netherlands) case-control study including 899 brain tumor (645 neuroepithelial) cases aged 10-24 years and 1,910 sex-, age-, country-matched controls. Medical radiological history was collected through personal interview. We estimated brain IR dose for each procedure, building a look-up table by age and time period. Lifetime cumulative doses were calculated using 2 and 5 years lags from the diagnostic date. Risk was estimated using conditional logistic regression. Neurological, psychological and genetic conditions were evaluated as potential confounders. The main analyses focused on neuroepithelial tumors. Results: Overall, doses were very low, with a skewed distribution (median 0.02 mGy, maximum 217 mGy). ORs for post-natal exposure were generally below 1. ORs were increased in the highest dose categories both for post and pre-natal exposures: 1.63 (95% CI 0.44-6.00) and 1.55 (0.57-4.23), respectively, based on very small numbers of cases. The change in risk estimates after adjustment for medical conditions was modest. Conclusions: There was little evidence for an association between IR from radio-diagnostic procedures and brain tumor risk in children and adolescents. Though doses were very low, our results suggest a higher risk for pre-natal and early life exposure, in line with current evidence. This work was funded by the EC Seventh Framework Programme (FP7/2007–2013) under the MOBI-Kids project (Grant No. 226873) and GERoNiMO project (Grant No. 603794). International coordination of the project was also supported by the Spanish Ministry of Science and Innovation (Grant EUS2008-03626). It has also been supported by the Spanish Health Research Fund (FIS PI10/02981), the Andalusian Consejeria de Salud (PI-0317/2010) and Conselleria de Sanitat, Generalitat Valenciana (Grant No. 025/2010.)

Published
2020

30. Peri-operative Prognostic Factors for Primary Skull Base Chordomas

Author

Corte, Emanuele La, Broggi, Morgan, Raggi, Alberto, Schiavolin, Silvia, Acerbi, Francesco, Danesi, Giovanni, Farinotti, Mariangela, Felisati, Giovanni, Maccari, Alberto, Pollo, Bianca, Saini, Marco, Toppo, Claudia, Valvo, Francesca, Ghidoni, Riccardo, Bruzzone, Maria Grazia, Dimeco, Francesco, and Ferroli, Paolo

Published
2020
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31. Exposure to Medical Radiation during Fetal Life, Childhood and Adolescence and Risk of Brain Tumor in Young Age: Results from the MOBI-Kids Case-Control Study

Author

IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Pasqual, Elisa, Castanõ-Vinyals, Gemma, Thierry-Chef, Isabelle, Kojimahara, Noriko, Sim, Malcolm R., Kundi, Michael, Krewski, Daniel, Momoli, Franco, Lacour, Brigitte, Remen, Thomas, Radon, Katja, Weinmann, Tobias, Petridou, Eleni, Moschovi, Maria, Dikshit, Rajesh, Sadetski, Siegal, Maule, Milena, Farinotti, Mariangela, Ha, Mina, T'Mannetje, Andrea, Alguacil, Juan, Aragonés, Nuria, Vermeulen, Roel, Kromhout, Hans, Cardis, Elisabeth, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Pasqual, Elisa, Castanõ-Vinyals, Gemma, Thierry-Chef, Isabelle, Kojimahara, Noriko, Sim, Malcolm R., Kundi, Michael, Krewski, Daniel, Momoli, Franco, Lacour, Brigitte, Remen, Thomas, Radon, Katja, Weinmann, Tobias, Petridou, Eleni, Moschovi, Maria, Dikshit, Rajesh, Sadetski, Siegal, Maule, Milena, Farinotti, Mariangela, Ha, Mina, T'Mannetje, Andrea, Alguacil, Juan, Aragonés, Nuria, Vermeulen, Roel, Kromhout, Hans, and Cardis, Elisabeth

Published
2020

32. Peri-operative prognostic factors for primary skull base chordomas: results from a single-center cohort.

Author

La Corte, Emanuele, primary, Broggi, Morgan, additional, Raggi, Alberto, additional, Schiavolin, Silvia, additional, Acerbi, Francesco, additional, Danesi, Giovanni, additional, Farinotti, Mariangela, additional, Felisati, Giovanni, additional, Maccari, Alberto, additional, Pollo, Bianca, additional, Saini, Marco, additional, Toppo, Claudia, additional, Valvo, Francesca, additional, Ghidoni, Riccardo, additional, Bruzzone, Maria Grazia, additional, DiMeco, Francesco, additional, and Ferroli, Paolo, additional

Published
2020
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37. Tau Mutations Serve as a Novel Risk Factor for Cancer

Author

Rossi, Giacomina, primary, Redaelli, Veronica, additional, Contiero, Paolo, additional, Fabiano, Sabrina, additional, Tagliabue, Giovanna, additional, Perego, Paola, additional, Benussi, Luisa, additional, Bruni, Amalia C., additional, Filippini, Graziella, additional, Farinotti, Mariangela, additional, Giaccone, Giorgio, additional, Buiatiotis, Simona, additional, Manzoni, Claudia, additional, Ferrari, Raffaele, additional, and Tagliavini, Fabrizio, additional

Published
2018
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38. Low quality of life and psychological wellbeing contrast with moderate perceived burden in carers of people with severe multiple sclerosis

Author

Giordano, Andrea, primary, Cimino, Vincenzo, additional, Campanella, Angela, additional, Morone, Giovanni, additional, Fusco, Augusto, additional, Farinotti, Mariangela, additional, Palmisano, Lucia, additional, Confalonieri, Paolo, additional, Lugaresi, Alessandra, additional, Grasso, Maria Grazia, additional, Ponzio, Michela, additional, Veronese, Simone, additional, Patti, Francesco, additional, and Solari, Alessandra, additional

Published
2016
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42. Dietary interventions for multiple sclerosis

Author

Farinotti, M, Vacchi, L, Simi, S, Di Pietrantonj, C, Brait, L, Filippini, G, Farinotti, Mariangela, Vacchi, Laura, Simi, Silvana, Di Pietrantonj, Carlo, Brait, Lorenzo, Filippini, Graziella, Farinotti, M, Vacchi, L, Simi, S, Di Pietrantonj, C, Brait, L, Filippini, G, Farinotti, Mariangela, Vacchi, Laura, Simi, Silvana, Di Pietrantonj, Carlo, Brait, Lorenzo, and Filippini, Graziella

Abstract

BackgroundClinical and experimental data suggest that certain dietary regimens, particularly those including polyunsaturated fatty acids PUFAs) and vitamins, might improve outcomes in people with multiple sclerosis MS). Diets and dietary supplements are much used by people with MS in the belief that they might improve disease outcomes and overcome the effectiveness limits of conventional treatments.This is an update of the Cochrane review "Dietary intervention for multiple sclerosis" first published on The Cochrane Library 2007, Issue 1).ObjectivesTo answer MS patients' questions regarding the efficacy and safety of dietary regimens for MS. Can changes in dietary habits be an effective intervention for MS patients? Are the potential side effects of these interventions known, and have they been measured? Are potential interactions between dietary interventions and other curative or symptomatic treatments known and have they been studied?Search methodsWe searched the Cochrane Multiple Sclerosis and Rare Diseases of the Central Nervous System Group Specialised Register November 2011), CENTRAL The Cochrane Library 2011, Issue 4), MEDLINE PubMed) 1966 to November 2011), EMBASE embase.com) 1974 to November 2011) and reference lists of papers found.Selection criteriaAll controlled trials randomised controlled trials RCTs) and controlled clinical trials CCTs)) on a specific dietary intervention, diet plan or dietary supplementation, except for vitamin D supplementation, compared to no dietary modification or placebo were eligible.Data collection and analysisTwo review authors independently selected articles, assessed trial quality and extracted data. Data were entered and analysed in RevMan.Dichotomous data were summarised as relative risks RR) with 95% confidence intervals 95% CI) using a random-effects model in the presence of heterogeneity (I-2 > 60%). Continuous data were analysed using weighted mean differences, determined by the difference between the pre- and post

Published
2012

44. DNA Microarray Analysis Identifies CKS2 and LEPR as Potential Markers of Meningioma Recurrence

Author

Menghi, Francesca, primary, Orzan, Francesca N., additional, Eoli, Marica, additional, Farinotti, Mariangela, additional, Maderna, Emanuela, additional, Pisati, Federica, additional, Bianchessi, Donatella, additional, Valletta, Lorella, additional, Lodrini, Sandro, additional, Galli, Giuseppe, additional, Anghileri, Elena, additional, Pellegatta, Serena, additional, Pollo, Bianca, additional, and Finocchiaro, Gaetano, additional

Published
2011
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46. Prognostic factors for survival in 676 consecutive patients with newly diagnosed primary glioblastoma

Author

Filippini, Graziella, primary, Falcone, Chiara, additional, Boiardi, Amerigo, additional, Broggi, Giovanni, additional, Bruzzone, Maria G., additional, Caldiroli, Dario, additional, Farina, Rita, additional, Farinotti, Mariangela, additional, Fariselli, Laura, additional, Finocchiaro, Gaetano, additional, Giombini, Sergio, additional, Pollo, Bianca, additional, Savoiardo, Mario, additional, Solero, Carlo L., additional, and Valsecchi, Maria G., additional

Published
2008
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47. Dietary interventions for multiple sclerosis

Author

Farinotti, Mariangela, primary, Simi, Silvana, additional, Di Pietrantonj, Carlo, additional, McDowell, Nicola, additional, Brait, Lorenzo, additional, Lupo, Daniela, additional, and Filippini, Graziella, additional

Published
2007
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49. Multiple Sclerosis Quality of Life-54--Italian Version

Author

Solari, Alessandra, primary, Filippini, Graziella, additional, Mendozzi, Laura, additional, Ghezzi, Angelo, additional, Cifani, Stefania, additional, Barbieri, Elena, additional, Baldini, Silvana, additional, Salmaggi, Andrea, additional, La Mantia, Loredana, additional, Farinotti, Mariangela, additional, Caputo, Domenico, additional, and Mosconi, Paola, additional

Published
1999
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