1. Coriorretinopatia Serosa Central: Resultados a Longo Prazo Após Terapia Fotodinâmica
- Author
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Sousa Pereira, Pedro Nuno, Ferreira, Sofia Catal��o, Soares, M��rio, Melo, Pedro, Farinha, Cl��udia, Marques, Jo��o Pedro, Pires, Isabel, Cachulo, Maria Luz, Murta, Joaquim, and Silva, Rufino
- Subjects
Chorioretinopathy/drug therapy ,genetic structures ,Photochemotherapy ,Verteporfina/uso terapêutico ,Verteporfin/therapeutic use ,Fotoquimioterapia ,sense organs ,eye diseases ,Coriorretinopatia Serosa Central/tratamento farmacológico - Abstract
Introduction: Central serous chorioretinopathy (CSC) is an idiopathic syndrome characterized by neurosensory detachments of the retina. Development of chronic CSC is an indication to treat, and ICGA-guided verteporfin photodynamic therapy has been shown to be very effective. Our objective was to evaluate the 13-year follow-up of chronic CSC patients treated with standard-fluence PDT and to explore the long-term microstructural and vascular choroidal changes related to the disease and treatment. Methods: Retrospective, interventional case-series analysis was conducted on 18 patients with cCSC, treated with standard PDT. Evaluations were performed every 3 months in the first year, every 6 months during the second year, and annually thereafter. All participants underwent a comprehensive ophthalmic examination. Retinal and choroidal imaging was performed with SD-OCT, SS-OCT, Optomap and OCTA. Results: Twenty-three eyes of eighteen patients were included, with a mean age of 63.9��8.5 years. The mean follow-up was 15.8��1.4 years. The mean number of sPDT treatments was 1.2��0.4. At baseline, subretinal fluid was found in all eyes, RPE proliferation in 9.1% and atrophy in 9.1% of the eyes. There was not a statistically significant improvement in BCVA, despite an initial mean gain of 5.08��10.36 letters at month 12 (p, Revista Sociedade Portuguesa de Oftalmologia, Vol. 45 N.�� 4 (2021)
- Published
- 2021