123 results on '"Farih MH"'
Search Results
2. LOCALLY ADVANCED BLADDER EWINGS SARCOMA: AN EXCEPTIONAL CASE REPORT
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Hanena, SM., primary, Amine, ED-Degouj, additional, Tidahy, R., additional, Ahsaini, M., additional, Mellas, S., additional, Ammari, J. EL, additional, Tazi, MF., additional, Fassi, JM. EL, additional, and Farih, MH., additional
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- 2021
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3. Histoprognostic Factors in Bladder Cancer: A Case Series of 156 Patients
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Benhayoune K, Tahiri L, Mellas S, Tazi F, Khallouk A, El Fassi J, Farih MH, and El Fatemi H
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Pulmonary and Respiratory Medicine ,business.industry ,Lymphocyte ,medicine.medical_treatment ,T cell ,Cell ,Cancer ,Immunotherapy ,medicine.disease ,medicine.anatomical_structure ,Immune system ,Cancer cell ,Immunology ,medicine ,Pediatrics, Perinatology, and Child Health ,Receptor ,business - Abstract
Background: For a long time, phenomenon of defective immune-surveillance in cancer patients from pathological standpoint was not elucidated. I have reported 1985 that lowering seral cyclic AMP is biochemical reason of defective immunesurveillance from adoptive lymphocyte immunotherapy experiment among cancer patients. Recently, Honjo Tasku et al., reported why T cell don’t attack cancer cells by the covering of PD-L1 on its receptor of PD-1. This is also one of defective immune-surveillance from cellular side. I have recently surveyed the correlation between seral cyclic AMP concentration and immune activity in cancer patients. I have confirmed the biochemical reason of lowering cyclic AMP leads to seral defective immune-surveillance in cancer patient’s serum. Methods: I have surveyed seral cyclic AMP concentration and T cell number and NK cell among 40 cancer patients and preclinical cancer patients. Results: The averaged seral cyclic AMP has a positive tendency between lower immune activity and lower cyclic AMP in the serum when cancer is developing beforehand. Conclusion: As cyclic AMP is elevated after fasting therapy, adoptive lymphocyte immunotherapy become useful as immuno-potentiation even if in advanced cancer patients.
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- 2018
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4. Retroperitoneal-necrotizing fasciitis due to chronic pyelonephritis
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EL Ammari, JE, primary, Ahssaini, M, additional, EL Fassi, MJ, additional, and Farih, MH, additional
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- 2010
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5. Urachal sinus presenting with abscess formation.
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El Ammari JE, Ahallal Y, El Yazami Adli O, El Fassi MJ, and Farih MH
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Urachal affections are rare. Their variable ways of presentation may represent a diagnostic challenge. Urachal sinuses are a rare type of these abnormalities. They are usually incidental findings and remain asymptomatic unless a complication (most commonly the infection) occurs. Infection of the urachal sinus would clinically present as purulent umbilical discharge, abdominal pain, and periumbilical mass. We report herein a case of infected urachal sinus in male adult. The diagnosis was suspected clinically and confirmed with ultrasonography and computed tomography scan. A preoperative cysto-fibroscopy showed normal aspect of the bladder and excluded sinus communication. An initial broad spectrum antibiotic therapy followed by complete excision of the sinus and fibrous tract without cuff of bladder has been therefore performed. The postoperative course was uneventful. No recurrence was observed after 18 months of followup. Histological examination did not reveal any sign of malignancy. [ABSTRACT FROM AUTHOR]
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- 2011
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6. Unilateral exophthalmos revealing metastatic prostate cancer.
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El Yazami Adli O, Elammari JE, Elfassi MJ, and Farih MH
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- 2012
7. [Prevalence and severity of erectile dysfunction in patients with type 2 diabetes in the Department of Urology at the University Hospital Center Hassan II, Fez, Morocco: a cross-sectional study of 96 cases].
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Ahsaini M, Omana JP, Mellas S, Ammari JEE, Tazi MF, Fassi MJE, and Farih MH
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- Adult, Aged, Cross-Sectional Studies, Diabetes Mellitus, Type 2 therapy, Diet Therapy, Disease Progression, Erectile Dysfunction etiology, Erectile Dysfunction therapy, Hospitals, University, Humans, Hypoglycemic Agents administration & dosage, Insulin administration & dosage, Male, Middle Aged, Morocco, Prevalence, Surveys and Questionnaires, Diabetes Mellitus, Type 2 complications, Erectile Dysfunction epidemiology, Mass Screening
- Abstract
Introduction: type 2 diabetes is a very common condition which, in some patients, may cause erectile dysfunction. The purpose of this study is to determine the prevalence and severity of erectile dysfunction in patients with type 2 diabetes attending the Department of Urology., Methods: we conducted a cross-sectional and descriptive study in the Department of Urology at the University Hospital Center Hassan II in Fez using a self-administered questionnaire encompassing an "International Index of Erectile Function-5" test based on 5 questions with routine blood test results in diabetic patients., Results: a total of 96 anonymous questionnaires were distributed over a 12-month period. The average age of patients was 53.5 years, 35% (n=34) of them were active smokers. Diabetes had progressed for over 10 years in 54% (n=52) of cases. Three patients were treated with diet alone, 32% (n=31) with oral antidiabetic drugs, 31% (n=30) with insulin therapy alone and 31% (n=30) with insulin and oral antidiabetic drugs. Only 11% (n=11) of patients had HbA1c below 7%. Patients reporting erectile dysfunction accounted for 70% (n=67) of surveyed patients. The proportion of patients with erectile dysfunction according to the International Index of erectile function-5 was 88% (n=84). The onset of erectile dysfunction had started more than 3 years earlier in 63% (n=60) of patients. Disorders started progressively in 90% (n=86) of patients. Screening rate was 37.5% (n=36), only 30% (n=29) of patients received phosphodiesterase type 5 inhibitors, then intracavernous injection or both. Forty-two per cent (n=40) of patients had either macro or micro-angiopathic complications., Conclusion: erectile dysfunction is a common but little suspected condition in diabetic men. Hence, the importance of systematic screening in any diabetic patient and of adequate treatment for sexual and cardiovascular disorders., Competing Interests: Les auteurs ne déclarent aucun conflit d´intérêts., (Copyright: Mustapha Ahsaini et al.)
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- 2020
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8. [Psoriasis of the glans penis in circumcised subjects].
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Ennaciri S and Farih MH
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- 2020
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9. Ischemia of the Penis and Fingertips Secondary to Calcifying Uremic Arteriolopathy.
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Jroundi H, El Alj W, Manescu MR, Bentata Y, and Farih MH
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Calcifying uremic arteriolopathy (CUA), also called calciphylaxis, refers to the calcification of the walls of the arteries of medium and small caliber, causing ischemic skin lesions. Diagnosis should be made if ischemic lesion develops in a patient with chronic renal failure (CRF), and it is confirmed based on clinical, radiological, and histological criteria. Generalized CUA characterized by ischemia of the penis (IP) along with other localizations of cutaneous ischemia is exceptional, and the morbidity and high mortality rate associated with this entity most often warrant multidisciplinary and conservative management., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2020, Jroundi et al.)
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- 2020
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10. [Multiple stones of the prostatic urethra associated with anejaculation revealing spinal dysraphism such as tethered cord syndrome at the base of the spinal canal in a young man: about an exceptional case].
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Ahsaini M, Mellouki A, Mellas S, El Ammari J, Tazi MF, El Fassi MJ, and Farih MH
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- Adult, Humans, Incidental Findings, Male, Quality of Life, Spinal Canal pathology, Spinal Dysraphism physiopathology, Urethra pathology, Urinary Calculi complications, Neural Tube Defects diagnosis, Sexual Dysfunction, Physiological etiology, Spinal Dysraphism diagnosis, Urinary Calculi diagnosis
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Spinal dysraphism (or spina bifida) is a neurological disorder representing the first cause of congenital urological disability. It has several clinical manifestations, vesicosphincteric and sexual disorders are frequent and rarely isolated, belonging to motor disorders, orthopedic, sensory, digestive or even cognitive impairments. Tethered cord syndrome at the base of the spinal canal is a complication of spinal dysraphism. This disorder is often detected in children, may be asymptomatic and found in adults. Bladder sphincter disorders are the main cause of morbi-mortality due to uronephrologic complications with a significant alteration in quality of life. This justifies specific management and multidisciplinary and strict monitoring. We here report an exceptional case of spinal dysraphism such as tethered cord syndrome at the base of the spinal canal found incidentally in an adult patient during an etiological assessment of lithiasis of the prostatic urethra associated with anejaculation ., Competing Interests: Les auteurs ne déclarent aucun conflit d'intérêts., (© Mustapha Ahsaini et al.)
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- 2019
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11. [Tuberculous vesicovaginal fistula complicated by bladder stones: about an exceptional case].
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Ahsaini M, Kharbach Y, Azelmad H, Mellas S, Elammari J, Tazi MF, Elfassi MJ, Farih MH, Sekal M, and Harmouch T
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- Antitubercular Agents administration & dosage, Biopsy, Discitis microbiology, Female, Follow-Up Studies, Humans, Middle Aged, Treatment Outcome, Tuberculosis, Spinal complications, Tuberculosis, Spinal drug therapy, Urinary Bladder Calculi pathology, Vesicovaginal Fistula etiology, Tuberculosis, Spinal diagnosis, Urinary Bladder Calculi diagnosis, Urinary Incontinence etiology, Vesicovaginal Fistula diagnosis
- Abstract
Vesicovaginal fistula (VVF) continues to be a major public health problem in developing countries. Given the particular association of VVF with stones, the question that arises is whether the fistula is primary or secondary to bladder stone and then whether to use single-stage or two-stage treatment. But what is special about this study is that these rare clinical features are due to tuberculosis. We here report the case of a 62-year old female patient with a history of treated tuberculous spondylodiscitis. The patient had been declared cured 4 years before. For the previous 2 years she had been suffering from continuous urinary incontinence. Clinical examination showed almost complete vaginal synechia. Complementary scannography and cystography showed the presence of 3 stones on the way to the VVF. The largest stone measured 6cm along its longer axis with passage of contrast material into the uterovaginal cavity through the fistula. The patient was admitted to the operating room where she underwent cystolithotomy with ablation of the stones that were on the way to the fistula, biopsy of the fistulous tract and single-stage closure of the VVF in two layers without interposition of the autologous tissue. Anatomopathological results confirmed the presence of active tuberculosis on the way to the fistula, requiring resumption of antibacillary treatment for 9 months. During the follow-up visit at 3, 6 and 9 months the patient showed good clinical status with absence of urinary incontinence. VVF secondary to tuberculosis associated with urinary stones appears very little in literature. Our case demonstrates the feasibility of antibacillar medical treatment associated with single-stage surgical treatment with very satisfactory results despite the history of our patient and the duration of his disease., Competing Interests: Les auteurs ne déclarent aucun conflit d'intérêts.
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- 2019
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12. [Metastatic bladder metachrone to a kaposi sarcoma cancer at a therapeutic impasse: about a case].
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Shamalirwa BB, Wembonyama O, Tidahy R, Mellas S, Ammari JEE, Tazi MF, Farih MH, Elmahi H, and Sidibe IS
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- Aged, Carcinoma, Transitional Cell drug therapy, Carcinoma, Transitional Cell secondary, Humans, Male, Urinary Bladder Neoplasms drug therapy, Urinary Bladder Neoplasms secondary, Carcinoma, Transitional Cell diagnosis, Sarcoma, Kaposi pathology, Urinary Bladder Neoplasms diagnosis
- Abstract
Chemotherapy is the treatment of choice for a metastatic urothelial bladder cancer. We here report a rare case of metastatic bladder cancer associated with Kaposi sarcoma posing a serious risk of aggravation of the new neoplasia. It was necessary to entrust the patient to his family., Competing Interests: Les auteurs ne déclarent aucun conflit d'intérêts.
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- 2019
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13. [Unusual intraurethral foreign body in a schizophrenic adolescent: about a case].
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Ahsaini M, Bounoual M, Mellas S, Ammari JE, Tazi MF, Fassi MJE, and Farih MH
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- Adolescent, Endoscopy methods, Foreign Bodies complications, Humans, Male, Needles, Foreign Bodies diagnosis, Schizophrenia complications, Self-Injurious Behavior psychology, Urethra injuries
- Abstract
Self- insertion of foreign body is a common practice for self-injure or erotic purpose in patients with chronic psychosis. The diagnosis is sometimes difficult if it is reported late or if the patient does not cooperate; hence the interest of complementary imaging assessment. Treatment was based on two steps: the extraction of the foreign body by endoscopy or open surgery and psychiatric treatment of the mental illness. We report the uncommon case of a 16-year old schizophrenic adolescent who had introduced a needle into the urethra 2 years before. Diagnosis was based on retrograde and mictional uretrocystography. The needle was removed with endoscopy as well as with technical artifices, without using open surgery despite the length of time the incident had occurred. The patient underwent complementary psychiatric treatment., Competing Interests: Les auteurs ne déclarent aucun conflit d'intérêts.
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- 2018
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14. [Giant hydronephrosis associated with ureterocele complicated by ureteral lithiasis].
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Ennaciri S and Farih MH
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- Humans, Hydronephrosis etiology, Hydronephrosis surgery, Laparoscopy methods, Low Back Pain etiology, Male, Middle Aged, Nephroureterectomy methods, Ureteral Calculi pathology, Ureterocele complications, Ureterocele surgery, Hydronephrosis diagnosis, Ureteral Calculi diagnosis, Ureterocele diagnosis
- Abstract
Giant hydronephrosis is defined as an extensive dilation of the pyelocaliceal cavities occupying a large part of the abdominal cavity or as a dilation filled up with more than a liter of urine overflowing the median line. This is due, more often, to pyelo-ureteral junction syndrome. Obstruction due to ureterocele complicated by lithiasis is a very rare cause of giant hydronephrosis. We here report the case of a 45-year old patient with a history of right lumbar pain which hadn't been investigated, presenting with abdominal mass evolving over the last few years associated with intermittent constipation. Clinical examination showed asymmetrical abdominal distension with dullness above the median line. Ultrasound showed multi-compartmentalized fluid-filled mass occupying all the right abdominopelvic region and pressing the digestive structures. Uroscanner showed right giant ureteropyelocaliceal dilation (pyelon measuring 15.2cm) completely eroding the renal parenchyma with absence of contrast agent excretion, upstream of ureterocele complicated by a stone measuring 2cm. Laparoscopic nephroureterectomy was performed. Post-operative suites were simple.
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- 2018
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15. A rare pure embryonal rhabdomyosarcoma of the urinary bladder in an adult successfully managed with neoadjuvant chemotherapy and surgery: a case report.
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Ahsaini M, Ouattar K, Azelmad H, Mellas S, Ammari JE, Tazi MF, Fassi MJ, Farih MH, Sekal S, and Harmouch T
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- Humans, Male, Middle Aged, Morocco, Rare Diseases diagnosis, Rare Diseases physiopathology, Rare Diseases therapy, Rhabdomyosarcoma, Embryonal diagnosis, Rhabdomyosarcoma, Embryonal physiopathology, Treatment Outcome, Urinary Bladder Neoplasms diagnosis, Urinary Bladder Neoplasms physiopathology, Antineoplastic Agents therapeutic use, Neoadjuvant Therapy methods, Rhabdomyosarcoma, Embryonal drug therapy, Rhabdomyosarcoma, Embryonal surgery, Urinary Bladder Neoplasms drug therapy, Urinary Bladder Neoplasms surgery
- Abstract
Background: Rhabdomyosarcoma of the urinary bladder in adults is an extremely rare malignant neoplasm that develops from the bladder wall., Case Presentation: We report our experience of a rare case of rhabdomyosarcoma of the bladder in a 45-year-old Moroccan man who was successfully managed with neoadjuvant chemotherapy and surgical excision of the mass; he was disease free at 24-month follow up., Conclusions: To the best of our knowledge, this is the first reported case of a rare embryonal rhabdomyosarcoma of the bladder that was managed with neoadjuvant chemotherapy and surgery. This is why further studies using a large number of patients with a greater longitudinal follow up will be required.
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- 2018
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16. [Neglected scrotal trauma revealing embryonic paratesticular rhabdomyosarcoma: about a case].
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Ahsaini M, Mellouki A, Ouattar K, Azelmad H, Mellas S, Ammari J, Tazi MF, Fassi MJ, and Farih MH
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- Adolescent, Combined Modality Therapy, Humans, Male, Rhabdomyosarcoma pathology, Rhabdomyosarcoma therapy, Scrotum pathology, Testicular Neoplasms pathology, Testicular Neoplasms therapy, Rhabdomyosarcoma diagnosis, Scrotum injuries, Testicular Neoplasms diagnosis
- Abstract
Embryonic paratesticular rhabdomyosarcoma is a rare mesenchymal tumor constituting a diagnostic and therapeutic emergency. Localized forms have a favorable prognosis. Multimodal treatment is the gold standard and it is based on surgery, multidrug chemotherapy and radiotherapy, with excellent overall survival rate. We here report the case of a 17-year old patient treated in our Department for embryonic fusiform cell paratesticular rhabdomyosarcoma causing clinical confusion. This study aims to highlight the specific features of this disease.
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- 2018
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17. Penile metastasis from rectal adenocarcinoma: a case report.
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Efared B, Ebang GA, Tahirou S, Tahiri L, Sidibé IS, Erregad F, Sow A, Hammas N, Farih MH, Chbani L, and El Fatemi H
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- Humans, Immunohistochemistry, Magnetic Resonance Imaging, Male, Middle Aged, Penile Neoplasms diagnostic imaging, Penile Neoplasms pathology, Prostate-Specific Antigen metabolism, Adenocarcinoma pathology, Penile Neoplasms secondary, Rectal Neoplasms pathology
- Abstract
Background: Despite its rich vasculature, the penis is rarely involved by metastasis. Since the first description of penile metastasis in 1870, fewer than 500 cases have been reported in the literature. The pelvic organs are the main source of primary tumors that metastasize to the penis., Case Presentation: We report a case of a 46-year-old Arabic man who presented with erectile dysfunction and painful induration of the penile root. Eight months ago, he had undergone abdomino-perineal resection for rectal adenocarcinoma after neo-adjuvant chemotherapy. The histological evaluation of the resected specimen disclosed a ypT3N0 tumor with a poor therapeutic response (around 5%). An adjuvant chemotherapy by XELOX (oxaliplatin plus capecitabine) regimen has been prescribed for the patient. The magnetic resonance imaging (MRI) showed tumoral infiltration of penile structures and a biopsy of the corpora cavernosa was performed. The histological examination disclosed a penile metastasis from the patient's previous rectal adenocarcinoma. The patient is still alive and continues his adjuvant therapy., Conclusion: Penile secondary tumors are very rare and usually occur in patients with advanced tumor stages. A diagnosis of penile metastasis should be considered in patients with a history of malignancies who present with genitourinary symptoms. These patients have a dismal prognosis as they often die in the year after the diagnosis.
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- 2017
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18. [Retroperitoneal fibrosis: about 12 cases].
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Majdoub AE, Khallouk A, and Farih MH
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- Adult, Aged, Aorta pathology, Drainage methods, Female, Humans, Male, Middle Aged, Morocco, Retroperitoneal Fibrosis complications, Retroperitoneal Fibrosis physiopathology, Retrospective Studies, Tomography, X-Ray Computed, Vena Cava, Inferior pathology, Low Back Pain etiology, Renal Insufficiency etiology, Retroperitoneal Fibrosis diagnosis
- Abstract
Retroperitoneal fibrosis (RPF) is rare. It is characterized by the gradual transformation of retroperitoneal adipose tissue into a fibrous mass surrounding the aorta, the inferior vena cava and the urinary tract responsible for progressive alteration in the renal function. It usually manifests as lumbar pain associated with renal failure and biologic inflammatory syndrome. We report 12 cases of retroperitoneal fibrosis in order to determine its clinical, radiological and therapeutic features. We conducted a retrospective study of 12 patients with retroperitoneal fibrosis whose medical data were collected in the Departement of Urology at the University Hospital Hassan II, Fes over a period of 9 years (2005-2013). The study involved ten men and two women. Clinical symptomatology was very variable, dominated by lumbar pain in all patients and hydrocele in 1 patient. Laboratory tests showed renal failure in all patients and inflammatory syndrome in 10 patients. The diagnosis of retroperitoneal fibrosis was suspected in all patients on ultrasound showing obstruction of the upper urinary tract without visible obstacle. The diagnosis was confirmed by abdominal CT scan without contrast that objectified a retroperitoneal tissue lesion enveloping the vessels and the urinary tract. Nine patients had idiopathic retroperitoneal fibrosis. Two patients had perianeurysmal fibrosis and one patient had post-radiation fibrosis. All patients underwent urinary drainage by double J. ureteral catheter. Seven patients underwent corticosteroid therapy. Six patients had an improvement of clinical and laboratory test outcome with disappearance of pain and improvement of the general condition. This study confirms the rarity of retroperitoneal fibrosis, the difficulty of diagnosis, pain associated with inflammatory syndrome and renal failure as common manifestations. Abdominal CT scan without contrast is the gold standard for definitive diagnosis. Urinary drainage is essential in most cases as well as regular monitoring of patients.
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- 2017
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19. [Aggressive renal angiomyolipoma extending to the renal vein: about a case and literature review].
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Majdoub AE, Khallouk A, and Farih MH
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- Adult, Angiomyolipoma pathology, Female, Humans, Kidney Neoplasms pathology, Magnetic Resonance Imaging methods, Renal Veins diagnostic imaging, Tomography, X-Ray Computed methods, Angiomyolipoma diagnostic imaging, Kidney Neoplasms diagnostic imaging, Renal Veins pathology
- Abstract
Renal angiomyolipoma is a benign tumor. It is characterized of three different components: muscular, vascular and greasy. Their distribution is variable. Diagnosis is based on the identification of the intratumoral greasy component on CT scan and MRI. In exceptional circumstances, this tumor may be aggressive with locoregional and venous extension (renal vein and inferior vena cava). We here report the case of a 37-year old patient with voluminous renal angiomyolipoma extending to the renal vein.
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- 2017
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20. Urolithiasis secondary to primary obstructive megaureter in an adult: a case report.
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Tenkorang S, Omana JP, Mellas S, Tazi FM, El Ammari JE, Khallouk A, El Fassi MJ, and Farih MH
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- Adult, Hematuria, Humans, Kidney Calculi diagnostic imaging, Male, Treatment Outcome, Ureteral Obstruction diagnostic imaging, Ureteral Obstruction physiopathology, Urography, Urolithiasis diagnostic imaging, Urolithiasis physiopathology, Flank Pain diagnostic imaging, Kidney Calculi surgery, Nephroureterectomy methods, Tomography, X-Ray Computed, Ureteral Obstruction surgery, Urolithiasis surgery
- Abstract
Background: Primary obstructive megaureter is relatively uncommon in adults. This condition usually regresses spontaneously or is treated during infancy. It can remain asymptomatic for decades until adulthood when symptoms may manifest in the event of complications or during a routine radiologic imaging. Primary obstructive megaureter has been reported to favor stone formation in the upper urinary tract., Case Presentation: We present the case of a 35-year-old Moroccan man who had a 10-year history of intermittent left flank pain and hematuria. A computed tomography urogram revealed a left megaureter with giant ureteral and renal calculi., Conclusions: Primary obstructive megaureter should be a differential diagnosis in an adult with hydroureteronephrosis associated with urolithiasis especially when there is kidney impairment. Through this case report we will discuss the diagnosis and management of primary obstructive megaureter associated with urolithiasis in adults.
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- 2017
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21. Myxoma of the kidney - an unusual benign renal tumor: a case report.
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Tenkorang S, Kharbach Y, Omana JP, Efared B, Mellas S, Tazi MF, Sekal M, Harmouch T, Khallouk A, El Fassi JM, El Ammari JE, and Farih MH
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- Diagnosis, Differential, Female, Humans, Kidney Neoplasms diagnostic imaging, Kidney Neoplasms surgery, Middle Aged, Myxoma diagnostic imaging, Myxoma surgery, Nephrectomy, Soft Tissue Neoplasms diagnostic imaging, Soft Tissue Neoplasms surgery, Tomography, X-Ray Computed, Kidney Neoplasms pathology, Myxoma pathology, Soft Tissue Neoplasms pathology
- Abstract
Background: Myxomas are rare benign soft tissue tumors. The kidney is an unusual location for this tumor. For this reason, less than 15 cases of renal myxoma have been reported in the English literature. There are no specific clinical and radiological features reported for this tumor that allow a preoperative diagnosis enabling a conservative treatment., Case Presentation: We report another case of renal myxoma found in a 50-year-old Moroccan woman who presented with a right dull flank pain. An abdominal computed tomography scan objectified a suspected malignant renal mass. Thus, radical nephrectomy was performed. Histopathology of the specimen revealed the typical appearance of a myxoma., Conclusions: The objective of this report is to add another case report of this rare benign renal tumor to the literature. This benign tumor with excellent prognosis has no specific preoperative features that could justify a conservative management; a radical approach remains the therapeutic option for now.
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- 2017
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22. [Diagnostic criteria and management options for renal angiomyolipoma: about 8 cases].
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El Majdoub A, Khallouk A, and Farih MH
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- Adolescent, Adult, Angiomyolipoma pathology, Angiomyolipoma therapy, Female, Humans, Kidney Neoplasms pathology, Kidney Neoplasms therapy, Male, Middle Aged, Retrospective Studies, Tomography, X-Ray Computed methods, Ultrasonography methods, Young Adult, Angiomyolipoma diagnostic imaging, Kidney Neoplasms diagnostic imaging, Tuberous Sclerosis complications
- Abstract
Renal angiomyolipoma is a benign renal tumor with a fatty component. We here report a series of 8 cases in order to describe diagnostic criteria and management options for renal angiomyolipoma. We studied 8 cases of renal angiomyolipomas over a 4-year period. All patients underwent ultrasound and abdominal CT scan. The diagnosis was confirmed on the basis of imaging data in all the cases. Two patients had been treated for Bourneville's tuberous sclerosis since childhood. The average age was 42 years. Ultrasound showed a hypoechoic heterogeneous aspect in all the cases. CT scan allowed the detection of the fatty component. Radiological diagnosis of renal angiomyolipoma is mainly based on the detection of the fatty component. Its association with Bourneville's tuberous sclerosis is an additional diagnostic argument., Competing Interests: Les auteurs ne déclarent aucun conflit d'intérêts
- Published
- 2016
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23. [Conservative treatment in diabetic patients with emphysematous pyelonephritis: about five cases].
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El Majdoub A, Khallouk A, and Farih MH
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- Acute Disease, Adult, Anti-Bacterial Agents administration & dosage, Conservative Treatment methods, Diabetes Mellitus drug therapy, Drainage methods, Emphysema diagnostic imaging, Emphysema physiopathology, Female, Humans, Insulin administration & dosage, Middle Aged, Pyelonephritis diagnostic imaging, Pyelonephritis physiopathology, Retrospective Studies, Tomography, X-Ray Computed methods, Treatment Outcome, Diabetes Mellitus physiopathology, Emphysema therapy, Pyelonephritis therapy
- Abstract
Acute emphysematous pyelonephritis (EPN) is a severe kidney infection. Early and effective treatment is essential to reduce high mortality rates due to this disease. Our study aims to highlight the clinical and paraclinical features as well as the peculiarities of therapeutic management of this disease and focus on the possibility of conservative treatment in diabetic patients. We analyzed the medical records of patients with EPN treated in the Department of Urology at the Hassan II University Hospital, Fez between January 2004 and January 2010. For each medical record we described clinical, paraclinical and therapeutic features as well as patient's evolution after treatment. We here report the case of 5 female patients whose average age was 45,6 years. All patients were diabetic. Lithiasic obstruction of the upper urinary tract was found in 3 patients (60%). The diagnosis was made by means of abdominal CT scan. All patients underwent resuscitation measures including antibiotic and insulin therapy. Conservative surgical procedure was performed in all cases. Indeed, surgical drainage of perirenal collections was performed in two cases, percutaneous renal drainage in one case and drainage using double-J ureteral catheter in 2 cases. Clinical and radiological evolution was excellent with renal preservation in all patients Emphysematous pyelonephritis is a rare and serious complication, especially in diabetic patients. Diagnosis is based on CT scan. Surgical treatment should be conservative in most cases, apart from severe forms, especially in diabetic patients who have potential risk of chronic renal failure., Competing Interests: Les auteurs ne déclarent aucun conflit d'intérêts.
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- 2016
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24. Isolated localization of Rosai Dorfman disease as renal mass: a case report and review of literature.
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El Majdoub A, El Houari A, Chbani L, El Fatemi H, Khallouk A, and Farih MH
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- Aged, Female, Histiocytosis, Sinus pathology, Histiocytosis, Sinus surgery, Humans, Lymph Node Excision methods, Lymphadenopathy diagnosis, Lymphadenopathy surgery, Histiocytosis, Sinus diagnosis, Kidney Neoplasms diagnosis, Nephrectomy methods
- Abstract
We report a rare case of an elderly woman presented with right renal mass with invasion of renal vein and several small lymphadenopathy in the hilar area. The diagnosis of kidney cancer is suspected and the patient underwent open radical nephrectomy, surrenalectomy and lymphadenectomy dissection. The pathologic examinations find a rosai dorfman disease. This unusual benign entity is uncommon in the kidney, but in medical imaging, it may simulate an infiltrative renal neoplasm, especially a lymphoma or leukemia or even renal cell carcinoma. A comprehensive literature review was undertaken to summarize the clinical and pathologic features of this disorder.
- Published
- 2016
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25. Fournier gangrene: rare complication of rectal cancer.
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Ossibi PE, Souiki T, Ibn Majdoub K, Toughrai I, Laalim SA, Mazaz K, Tenkorang S, and Farih MH
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- Anti-Bacterial Agents therapeutic use, Colectomy, Colon, Sigmoid surgery, Debridement, Early Diagnosis, Emergencies, Fournier Gangrene diagnosis, Fournier Gangrene drug therapy, Fournier Gangrene surgery, Humans, Male, Middle Aged, Necrosis, Perineum pathology, Scrotum pathology, Adenocarcinoma complications, Fournier Gangrene etiology, Rectal Neoplasms complications
- Abstract
Fournier's Gangrene is a rare complication of rectal cancer. Its discovery is often delayed. It's incidence is about 0.3/100,000 populations in Western countries. We report a patient with peritoneal perforation of rectal cancer revealed by scrotal and perineal necrotizing fasciitis.
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- 2015
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26. Suicide attempt by self-stabbing of the bladder: a case report.
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Kharbach Y, Tenkorang S, Ahsaini M, Mellas S, El Ammari J, Tazi MF, Khallouk A, El Fassi MJ, and Farih MH
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- Foreign Bodies diagnostic imaging, Foreign Bodies psychology, Humans, Male, Middle Aged, Tomography, X-Ray Computed, Urinary Bladder diagnostic imaging, Wounds, Stab diagnostic imaging, Suicide, Attempted, Urinary Bladder injuries, Wounds, Stab psychology
- Abstract
Introduction: The presence of foreign bodies in the bladder often falls within questionable practices in psychiatric settings or in iatrogenic instances such as during endoscopy or migration of foreign bodies around the bladder remaining after surgery on organs close to the bladder. Psychiatric disorders have been reported in patients admitted for self-introduction of foreign bodies in the bladder during an act of sexual satisfaction. However, to the best of our knowledge, no similar case in the context of suicide has been reported in the English-language literature., Case Presentation: A 56-year-old Moroccan man known to have untreated paranoid schizophrenia and a history of several previous suicide attempts was presented to the emergency unit of our hospital after self-stabbing with a 15 cm sewing needle. His stab wound was located at the hypogastric region of the abdomen, with full penetration of the needle into the abdomen. A computed tomographic scan showed a breach on the dome of the bladder responsible for extravasation of the contrast dye, which revealed a peritoneal cavity effusion of average abundance and a suspected lesion of the left pelvic ureter. An exploratory laparotomy was performed. Approximately 1000 mL of widely dispersed fluid was observed in the abdominal cavity. During exploration of the bladder, two centimetric intrabladder breaches were found, one of which was a breach of the left pelvic ureter without other associated lesions. The breaches were sutured, and a ureteral catheter was mounted. The patient's post-operative follow-up was unremarkable., Conclusions: The wide variety of ways that foreign bodies are introduced into the lower urinary tract pose diagnostic and therapeutic difficulties for the urologist. Management of these patients is facilitated by the use of endoscopy.
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- 2014
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27. Para testicular rhabdomyosarcoma in adults: three case reports and review of literature.
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Boudahna L, Benbrahim Z, Amaadour L, Mazouz A, Benhayoune K, Tahiri Y, Farih MH, Amarti A, Arifi S, and Mellas N
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- Adolescent, Adult, Humans, Male, Orchiectomy methods, Practice Guidelines as Topic, Rhabdomyosarcoma diagnosis, Rhabdomyosarcoma therapy, Testicular Neoplasms diagnosis, Testicular Neoplasms therapy, Treatment Outcome, Young Adult, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Rhabdomyosarcoma pathology, Testicular Neoplasms pathology
- Abstract
Paratesticular embryonal rhabdomyosarcoma (RMS) is a rare tumor arising from the mesenchymal tissues of the spermatic cord, epididymis, testis and testicular tunics. We report three cases of adult paratesticular RMS, two embryonic and one pleomorphic rhabdomyosarcoma. All the patients underwent diagnostic orchidectomy. The work up investigations revealed lung metastases. Chemotherapy with Ifosfamide and Doxorubicin was used in two cases, whereas Vincristin-Actinomycin D and Cyclophosphamide was received in one case. An objective partial response was reported in 2 cases, with complete response in one case. Paratesticular RMS is a rare and aggressive tumor. Because of the absence of protocols designed specifically for adult patients, it is necessary to follow therapeutic guidelines in pediatric protocols.
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- 2014
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28. Elective gangrene of the corpus spongiosum of idiopathic origin: A case report.
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Kharbach Y, Tenkorang S, Bouchikhi A, Mellas S, Ammari JE, Tazi MF, Khallouk A, Fassi MJ, and Farih MH
- Abstract
Penile gangrene is rare and associated with significant morbidity and mortality. It can be dry or wet. Treatment for dry gangrene is based on surgery, watchful waiting allowing spontaneous amputation of necrotic tissue or revascularization. It often depends on the general condition of the patient. We report a case of a 54-year-old patient with no significant medical history who presented with necrosis of the glans penis. Upon surgical exploration, we found an elective necrosis of the entire corpus spongiosum for which partial penectomy was performed. No etiology was found. To our knowledge, this is the first such case to be reported in the literature.
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- 2014
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29. Penile self-mutilation preceded by bizarre delusions: two case reports.
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Kharbach Y, Amiroune D, Ahsaini M, Bout A, Riyach O, Stuurman-Wieringa RE, Mellas S, Tazi MF, Khallouk A, El Fassi MJ, Rammouz I, and Farih MH
- Subjects
- Adult, Emergency Service, Hospital, Humans, Male, Self Mutilation diagnosis, Young Adult, Delusions complications, Penis injuries, Self Mutilation psychology
- Abstract
Introduction: Genital self-mutilation is listed as a symptom of borderline personality disorder. The type of injury varies from simple skin laceration to total amputation of the penis and testicles. These injuries are urological and surgical emergencies., Case Presentation: We report two cases of penile self-mutilation precipitated by erotic and religious bizarre delusions.Our first patient is a 24-year-old Moroccan man who visited our emergency room with a metallic ring at the root of his penis which had caused marked edema of his entire penis.Our second patient is a 26-year-old Moroccan man evaluated in our emergency unit. A clinical examination revealed a wound at the dorsal side of his penis with complete transection of the dorsal vein and imperfect hemostasis.The two patients were treated in our emergency unit after which a favorable clinical course was observed., Conclusion: Cases of genital self-mutilation are urological and psychiatric emergencies, therefore it is important that surgical and psychiatric teams collaborate closely while managing cases of genital self-mutilation.
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- 2014
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30. [Not Available].
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Kassogué A, El Ammari JE, Diarra A, Amiroune D, Ahsaini M, Ouldim K, Traoré Z, Sqalli HN, Tizniti S, Mellas S, Tazi MF, Khallouk A, El Fassi MJ, and Farih MH
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- 2014
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31. Atypical isolated urethral tuberculosis associated with inflammatory stenosis and fistulas.
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Bouchikhi AA, Khallouk A, El Fassi MJ, and Farih MH
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- 2014
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32. [Clinical and therapeutic aspects of priapism at CHU Gabriel Touré: study of 36 cases].
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Kassogué A, Coulibaly M, Ouattara Z, Diarra A, Tembely A, El Fassi MJ, Farih MH, and Ouattara K
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- Adolescent, Adult, Child, Hospitals, University, Humans, Male, Mali epidemiology, Retrospective Studies, Young Adult, Priapism diagnosis, Priapism epidemiology, Priapism therapy
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- 2014
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33. Successful replantation of an amputated penis: a case report and review of the literature.
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Riyach O, El Majdoub A, Tazi MF, El Ammari JE, El Fassi MJ, Khallouk A, and Farih MH
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- Adult, Humans, Male, Penis surgery, Amputation, Traumatic surgery, Penis injuries, Replantation methods
- Abstract
Introduction: Amputation of the penis is a rare traumatic injury reported from various parts of the world as isolated cases. A complete reconstruction of all penile structures should be attempted in one stage which provides the best chance for full rehabilitation of the patient., Case Presentation: We report the case of a 35-year-old Berber man who was admitted at the Emergency Department for incomplete criminal amputation of his penis, which was successfully reattached by using a macrosurgical technique. After surgery, near-normal appearance and function including a good urine flow and absence of urethral stricture, capability of erection and near normal sensitivity, were observed., Conclusions: The importance of using macrosurgical reimplantation in incomplete penile amputation in order to achieve better functional and cosmetic results is discussed. In addition, we also highlight the potential anatomical role of corpus spongiosum in the arterial and venous blood supply to the penis.
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- 2014
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34. Female urethral diverticulum: cases report and literature.
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Riyach O, Ahsaini M, Tazi MF, Mellas S, Stuurman-Wieringa R, Khallouk A, El Fassi MJ, and Farih MH
- Abstract
Introduction: A female urethral diverticulum is an uncommon pathologic entity. It can manifest with a variety of symptoms involving the lower urinary tract. Our objective is to describe the various aspects of the diverticulum of the female urethra such as etiology, diagnosis and treatment., Cases Presentation: We report five female patients, without prior medical history. They had different symptoms: dysuria in four cases, recurrent urinary tract infection in three cases, stress incontinence in two cases and hematuria in two cases. All patients had dyspareunia. The physical exams found renitent mass located in the endovaginal side of urethra which drained pus in two cases. Urethrocystography found a diverticulum of urethra in all cases. Our five patients underwent diverticulotomy by endovaginal approach. The course after surgical treatment was favorable. The urinary catheter was withdrawn after ten days. Some recurrent symptoms were reported., Conclusion: Evaluation of recurrent urinary complaints in young women can lead to the finding of a diverticulum of urethra. Urethrocystography can reveal this entity. Diverticulectomy by endovaginal approach is the best choice for treatment.
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- 2014
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35. Bilateral ureteral obstruction revealing a benign prostatic hypertrophy: a case report and review of the literature.
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Riyach O, Ahsaini M, Kharbach Y, Bounoual M, Tazi MF, El Ammari JE, Mellas S, Fassi Mel J, Khallouk A, and Farih MH
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Introduction: Prostatic hyperplasia is the most frequent tumor in men older than 50 years of age. Bilateral hydronephrosis secondary to benign prostatic hypertrophy is a rare condition most often due to vesicoureteral reflux. Herein we report a case of a patient with bilateral hydronephrosis with distal ureter obstruction caused by detrusor hypertrophy due to prostatic hyperplasia, our analysis of the clinical data and a review of the relevant published literature., Case Presentation: We report a case of a 65-year-old Berber man with clinically significant storage, bladder-emptying symptoms and bilateral low back pain with renal biologic failure and bilateral ureterohydronephrosis, distal ureteral stenosis, detrusor hypertrophy and prostate hyperplasia without significant post-void residual urine volume visualized by abdominal sonography. The patient underwent bilateral JJ stent insertion with transurethral resection of the prostate. The patient was discharged 3 days after surgery without any obvious complications. At his 3-month follow-up examination, the JJ stent was removed and the patient had comfortable urination without renal failure., Conclusion: This is an extremely rare condition that has important diagnostic considerations because of the possibility of comorbid severe obstructive uropathy and chronic renal failure.
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- 2014
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36. A huge renal cyst mimicking ascites: a case report.
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Riyach O, Ahsaini M, Tazi K, Tazi MF, Mellas S, El Ammari JE, Khallouk A, El Fassi MJ, and Farih MH
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- Aged, Diagnosis, Differential, Humans, Male, Sensitivity and Specificity, Tomography, X-Ray Computed methods, Ascites diagnosis, Kidney Diseases, Cystic diagnosis
- Abstract
Background: Renal cysts are common in old patients, and usually remain untreated. Giant renal cyst measuring more than 15 cm in diameter and containing more than 1500 mls of serous fluid are rarely seen. We report a case of a 75-year-old man with a giant right renal cyst., Case Presentation: A 75-year-old man presented with a five years history of suprapubic pain, abdominal distension. He had no urological symptoms. Physical examination revealed a distended abdomen with shifting dullness. Routine hematology, biochemistry, and serum tumor markers were within normal limits. Erroneously diagnosed as ascites on ultrasonographic examination. Abdominal paracentesis of supposed ascites was performed. The diagnosis of giant renal cyst was finally made by Computed tomography (CT) and patient underwent continuous percutaneous catheter drainage with negative pressure, whereby 8 liters of fluid were removed with negative cytology. Subsequent Computed tomography after 6 months revealed disparition of the cysts, and the patient remained asymptomatic., Conclusion: Giant renal cysts are uncommon; we conclude that the CT remains the best exam in patients evaluated for giant renal cyst. This to the best of our knowledge is the largest renal cyst in the medical literature. Studies are needed with particular attention to the factors associated with renal cyst enlargement.
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- 2014
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37. Verrucous carcinoma arising in an extended giant condyloma acuminatum (Buschke-Löwenstein tumor): a case report and review of the literature.
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Ahsaini M, Tahiri Y, Tazi MF, Elammari J, Mellas S, Khallouk A, El Fassi MJ, Farih MH, Elfatmi H, Amarti A, and Stuurman-Wieringa RE
- Abstract
Introduction: Verrucous carcinoma of the external genitalia and perianal region is a rare variant of well-differentiated squamous cell carcinoma. It has been reported to have limited metastatic potential., Case Presentation: We report the case of a 54 year-old Moroccan man who presented with locally advanced giant condyloma acuminatum (Buschke-Löwenstein tumor) after prolonged intervals of neglect (approximately 10 years). The disease covered his suprapubic, external genitalia and perianal region. It was locally aggressive with extensive tissue destruction. After a biopsy of the lesion, the diagnosis of verrucous carcinoma was confirmed. He initially received chemoradiotherapy, followed by extensive local excision, but he developed septic shock and died a few days later., Conclusions: The purpose of this case report is to present a case of verrucous carcinoma arising in an extensive giant condyloma acuminatum (Buschke-Löwenstein tumor) and discuss the literature on its diagnosis and management.
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- 2013
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38. [Not Available].
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Diarra A, Elammari JE, Kassogue A, El Fassi MJ, and Farih MH
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- 2013
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39. Emphysematous cystitis and emphysematous pyelitis: a clinically misleading association.
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Ahsaini M, Kassogue A, Tazi MF, Zaougui A, Elammari JE, Khallouk A, El Fassi MJ, and Farih MH
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- Diabetes Complications diagnosis, Diagnosis, Differential, Escherichia coli Infections complications, Escherichia coli Infections diagnosis, Humans, Male, Middle Aged, Radiography, Abdominal, Tomography, X-Ray Computed, Urinary Tract Infections complications, Urinary Tract Infections diagnosis, Cystitis complications, Cystitis diagnosis, Emphysema complications, Emphysema diagnosis, Pyelonephritis complications, Pyelonephritis diagnosis
- Abstract
We present a rare case of emphysematous cystitis associated with an emphysematous pyelonephritis in a diabetic Arab man who was admitted in a confusional state. A 60-year-old man was admitted to the emergency department with confusion and hypogastric mass. The Clinical examination found comatose patient with a mass in the tympanic hypogastric percussion. The pelvic computed tomography (CT) demonstrated intramural gas in the urinary tract, which suggested a diagnosis of emphysematous cystitis and emphysematous pyelitis. The treatment was based on an antibiotics associated with a bladder drainage and diabetes stabilization. The evolution was uneventful. Every diabetic patient with a urinary tract infection who seems to be severely ill should have an abdominal X-ray as a minimal screening tool to detect emphysematous complications. The rarity and the association with an emphysematous pyelitis, which is rarely reported in the literature, are two remarkable characteristics described in this case report.
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- 2013
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40. Tumor in undescended intrapelvic testis revealed by supraclavicular lymphadenopathy: a case report and literature review.
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Tazi MF, Riyach O, Ahsaini M, Ahallal Y, Khallouk A, El Fassi MJ, and Farih MH
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- Cryptorchidism surgery, Humans, Lymph Nodes diagnostic imaging, Lymph Nodes pathology, Male, Middle Aged, Testicular Neoplasms surgery, Testis pathology, Testis surgery, Tomography, X-Ray Computed, Cryptorchidism complications, Cryptorchidism diagnosis, Testicular Neoplasms diagnosis
- Abstract
Background: Testicular cancer is a rare disease. The incidence of testicular cancer in undescended testicles is of 3 to 48 times greater than in the general population. In the developed countries, the existence of undescended testicles in the adult population is rare, due to systematic practice of elective orchidopexy before the second year of life and orchiectomy in post adolescent males with undescended testicles. Despite these prevention measures, there are still some isolated cases of intra-abdominal testicular tumors in adults. We report a case of testicular cancer in cryptorchid testis revealed by supraclavicular lymphadenopathy., Case Presentation: We report a case of a 46 year old fertile man with a history of unilateral cryptorchidism who presented with a palpable left supraclavicular mass and absence of the right testicle. On investigations an intrapelvic testis tumor was diagnosed. Laparotomy and complete excision was carried out. The possible association between the undescended testis and cancer transformations is briefly discussed., Conclusion: Testicular cancer in undescended testicles should not be ignored. Only early diagnosis and lower of testis in scrotumprevent such clinical forms.
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- 2013
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41. Unilateral primitive hydatid cyst with surgical resection of the scrotum: a case report.
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Bouchikhi AA, Lamrani YA, Tazi MF, Mellas S, Elammmari J, Khallouk A, Elfassi MJ, and Farih MH
- Abstract
Introduction: Hydatid disease remains a public health problem in many Mediterranean countries. Liver and lung localizations are the most common. Renal hydatid cysts represent 2 percent to 4 percent of the visceral forms of this disease. To the best of our knowledge a scrotal location has only previously been described in five papers in the literature, all being secondary localizations. In this paper, we report a case of a primitive scrotal hydatid cyst., Case Presentation: A Moroccan man aged 29 years old presented to our facility with scrotal pain. A clinical examination identified a painless scrotal mass. The results of a scrotal ultrasound showed intra-scrotal cystic formations with different sizes associated with scrotal effusion of average abundance. Chest cavity and abdominal computed tomography scans did not reveal any other localizations. Our patient benefited from surgical protruding dome resection. A partial cysto-pericystectomy was realized. The first stage consisted of injecting a scolicide solution; hydrogen peroxide is the most commonly used agent. This is injected into the cystic cavity and retained for 10 minutes. This process allows for sterilization of the cyst while avoiding the risk of rupture and transmission of the hydatid liquid into the circulation. After 10 minutes, the cystic contents are removed by suction. The cyst is then opened, and the endocyst containing the hydatid membrane and daughter vesicles are removed. It is of note that our patient did not receive any additional medical treatment. Our diagnosis was made using an imaging approach and was confirmed during surgery., Conclusions: Ultrasound is often the key diagnostic approach for cases of a scrotal hydatid cyst. Treatment is primarily surgical, aiming for resection of the protruding dome via a longitudinal scrotectomy.
- Published
- 2013
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42. Isolated urethral tuberculosis in a middle-aged man: a case report.
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Bouchikhi AA, Amiroune D, Tazi MF, Mellas S, Elammari JE, El Fassi MJ, Khallouk A, and Farih MH
- Abstract
Introduction: Urogenital tuberculosis is a frequent disease in endemic countries. It is characterized by clinical polymorphism. The isolated urethral form is exceptional, even in countries with endemic tuberculosis. We present a rare case of urogenital tuberculosis in a man revealed by urethral narrowing and multiple urethro-scrotal fistulas., Case Presentation: The patient, a Moroccan man, was 40 years old. He visited our hospital for a urology consultation and presented with dysuria, purulent discharge and a meatic penoscrotal fistula. A retrograde and voiding urethrocystography was performed and revealed an extended narrowing of the whole anterior urethra associated with multiple fistulous portions toward the scrotum and perineum. At this stage, we reached a diagnosis of nonspecific sclero-inflammatory urethral stricture with complicating fistulas. We decided to perform a urethroplasty enlargement to clear the narrowing urethral sinus tracts. The evolution was marked by delayed wound healing associated with the persistence of fistulas extending into the corpus cavernosum with purulent discharge. It was at this point in the treatment that we suspected tuberculosis. Multiple biopsies were then performed on the periurethral tissue and fistula tracts. The histological examination confirmed urethral tuberculosis and showed the presence of giant cell epithelial lesions with caseous necrosis characteristic of tuberculosis. The treatment for tuberculosis was immediately established and the evolution was marked by a localized, rapid and significant improvement. A second-stage urethroplasty was scheduled for two months after the start of his antituberculous treatment., Conclusions: Urogenital tuberculosis is common, but isolated urethral involvement is very rare even in countries with endemic tuberculosis. We urge practitioners, and especially urologists, to consider the disease in their investigation whenever given clinical signs are declared.
- Published
- 2013
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43. Embryonic paratesticular rhabdomyosarcoma: a case report.
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Bouchikhi AA, Mellas S, Tazi MF, Lahlaidi K, Kharbach Y, Benhayoune K, Kanab R, Elammari JE, Khallouk A, El Fassi MJ, and Farih MH
- Abstract
Introduction: An embryonic paratesticular rhabdomyosarcoma is a very rare mesenchymal tumor. It is an intrascrotal tumor that is localized in paratesticular structures such as the epididymis or spermatic cord. Rhabdomyosarcoma is most often observed in children and adolescents, presenting as a painless scrotal mass., Case Presentation: Our patient was an 18-year-old Moroccan man who presented with a painless left scrotal mass that had evolved over four months. An inguinal orchiectomy was performed. A histological examination of the excised tissue revealed an embryonic rhabdomyosarcoma.Our patient had three sessions of chemotherapy with vincristine, actinomycin C and cyclophosphamide. Each chemotherapy session was conducted over five days, with a cycle of 21 days. Our patient was assessed two months after the last chemotherapy session and demonstrated good clinical improvement., Conclusion: Paratesticular rhabdomyosarcoma is a rare aggressive tumor manifesting in children and very young adults. Localized forms have a good prognosis whereas metastatic tumors show very poor results. A well-defined treatment based on surgery and chemotherapy yields good results.
- Published
- 2013
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44. Polycythemia vera revealed via a bladder tumor in a patient with erectile dysfunction: a case report.
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Bouchikhi AA, Tazi MF, Mellas S, Amiroune D, Elammari JE, Khallouk A, El Fassi MJ, and Farih MH
- Abstract
Introduction: Polycythemia vera is a polyglobular myeloproliferative syndrome related to the mutation of multipotent hemopoietic stem cells. This case report describes a patient whose bladder tumor was associated with polycythemia vera and erectile dysfunction. The association of bladder neoplasia with polycythemia vera and erectile dysfunction has not previously been reported in the literature., Case Presentation: A 40-year-old Moroccan man was followed up for a bladder tumor which manifested with coagulant hematuria and a facial erythrosis with a hemoglobin level of 20.3g/L suggesting polycythemia vera. The patient also suffered from an erectile disorder. Considering the anesthesia difficulty due to polyglobulia, the patient was treated by bleeding. This treatment enabled the patient's sexual performance to be improved and adjustment of his hemoglobin to a level allowing anesthesia, and hence surgical resection of his bladder tumor., Conclusion: Erectile dysfunction associated with polycythemia vera is elucidated by rheological disorders. Bleeding contributed to satisfactory sexual performance and facilitated treatment of polycythemia vera because it enabled anesthesia to be performed and hence the surgical resection of the bladder tumor.
- Published
- 2013
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45. Pseudotumoral tuberculous ureteritis: a case report.
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Bouchikhi AA, Amiroune D, Tazi MF, Mellas S, Elammari JE, El Fassi MJ, Khallouk A, and Farih MH
- Abstract
Introduction: Tuberculosis is still endemic in Morocco and the urogenital form is common. This form is characterized by clinical polymorphism. However, the isolated ureteric form is very rare. The differential diagnosis might be raised in tumoral cases while undertaking surgical excision which is the realistic choice. Hence, we report an isolated ureteric tuberculosis case, and we discuss the clinical, imaging, diagnostic and therapeutical features., Case Presentation: A 30-year-old Moroccan man consulted us for left back pain associated with urinary frequency and a few macroscopic episodes of hematuria for the past six months. A computed tomography urography revealed a left hydronephrosis and hydroureter secondary to focal wall thickening of the left lumbar ureter. Hence, we had diagnosed a ureteral tumor. However, a clinical examination showed irritative voiding symptoms and epididymal disorders associated with prostate infection suggesting a Koch's bacillus assessment of the patient's urine of which the results proved strongly positive. The treatment consisted of establishing a double-J ureteric stent to drain the left kidney, followed by antituberculous antibiotics., Conclusion: Urogenital tuberculosis is common in endemic countries, however isolated ureter affection is rare. It is important to consider a ureteral tuberculosis diagnosis whenever ureteral thickening is revealed in a patient living in a country in which tuberculosis is endemic.
- Published
- 2013
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46. Primary signet-ring cell carcinoma of the urinary bladder successfully managed with cisplatin and gemcitabine: a case report.
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El Ammari JE, Ahsaini M, Riyach O, El Fassi MJ, Farih MH, Hammas N, Elfatmi H, and Amarti A
- Abstract
Introduction: Primary signet-ring cell carcinoma of the urinary bladder is a rare variant of mucus-producing adenocarcinoma constituting approximately 0.5% to 2.0% of all primary carcinomas of the bladder. This tumor initially presents as a high-grade, high-stage lesion and diffusely invades the bladder wall without forming intraluminal growth. The patients have no specific symptoms, which leads to delayed diagnosis and poor prognosis., Case Presentation: We report the case of a 51-year-old Moroccan Berber man consulting for gross hematuria. Ultrasonography and a computed tomography scan found a bladder tumor diffusely invading the bladder wall. A histopathological examination of the tumor chips from a transurethral resection of the bladder revealed signet-ring cell adenocarcinoma. The gastrointestinal tract exploration did not reveal any other tumor localization. A radical cystectomy and adjuvant cisplatin and gemcitabine chemotherapy were therefore performed resulting in 18 months of survival without metastasis and a good quality of life within that time., Conclusion: The rarity and the successful management with carboplatin and gemcitabine as adjuvant chemotherapy of this entity, which is rarely reported in the literature, are two remarkable characteristics described in this case report.
- Published
- 2013
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47. Small cell neuroendocrine carcinoma of the urinary tract successfully managed with neoadjuvant chemotherapy.
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Ahsaini M, Riyach O, Tazi MF, El Fassi MJ, Farih MH, Elfatmi H, and Amarti A
- Abstract
Introduction. Small cell neuroendocrine carcinomas of the urinary tract is an extremely rare entity and very few cases have been reported in the literature. Small cell neuroendocrine carcinoma of the urinary tract (SCC-UT) is the association between bladder and urinary upper tract-small cell carcinoma (UUT-SCC). It characterized by an aggressive clinical course. The prognosis is poor due to local or distant metastases, and usually the muscle of the bladder is invaded. Case Presentation. We report a rare case of a 54-year-old Arab male native of moroccan; he is a smoker and was referred to our institution for intermittent hematuria. Following a diagnosis of small cell neuroendocrine carcinomas of the ureter and the bladder, thoracoabdominal-pelvic CT was done, and the staging of the tumor was done in the bladder (T2N0M0) and (T1N0M0) in the ureter. Neoadjuvant alternating doublet chemotherapy with ifosfamide/doxorubicin and etoposide/cisplatin was realized, and nephroureterectomy associated to a cystoprostatectomy was carried out. After 24 months of followup, no local or distant metastasis was detected. Conclusion. The purpose of this review is to present a rare case of pure small cell neuroendocrine carcinoma of the urinary tract and review the literature about the place of neoadjuvant chemotherapy in this rare tumors.
- Published
- 2013
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48. Acquired urethral diverticulum in a man with paraplegia presenting with a scrotal mass: a case report.
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El Ammari JE, Riyach O, Ahsaini M, Ahallal Y, El Fassi MJ, and Farih MH
- Abstract
Introduction: Male urethral diverticula are rare. Patients with paraplegia may present with acquired diverticula as a result of prolonged catheterization. Diverticula may be asymptomatic or lead to lower urinary tract symptoms. Rarely, the diverticulum may initially present as a scrotal mass., Case Presentation: We report the case of a male 45-year-old Arab with paraplegia who presented with a mass in the peno-scrotal junction. He had in his medical history iterative prolonged urethral catheterizations associated with urine leakage through the urethral meatus upon applying compression. Diagnosis confirmation of urethral diverticula is obtained by retrograde urethrography. The patient underwent a diverticulectomy with urethroplasty., Conclusion: Male acquired urethral diverticula can be found in patients who have a spinal cord injury because of prolonged urethral catheterization. Clinical presentations are different and sometimes can be misleading. Retrograde urethrography is the key to diagnosis and open surgery is the treatment of reference.
- Published
- 2012
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49. Pure choriocarcinoma of the testis presenting with jaundice: a case report and review of the literature.
- Author
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Ahsaini M, Tazi F, Mellas S, Elammari J, Khalouk A, Stuurman-Wieringa R, Elfassi MJ, Farih MH, Elfatmi H, and Amarti A
- Abstract
Introduction: Testicular cancer is the most common malignancy in men 15- to 35-years-old. The North American standard classification divides testicular cancers into germ cell tumors and non-germ cell tumors. The lymphatic spread of germ cell tumors usually involves the retroperitoneal lymph nodes. However, this spread to the retroperitoneum rarely involves the hepatic hilum. We describe an unusual case of metastatic choriocarcinoma of the testis that was clinically mimicked by a cholestatic jaundice. This is an unusual presentation of testicular cancer and, to the best of our knowledge, the first report of this kind in the literature., Case Presentation: A 28-year-old Moroccan man presented with a four-week history of progressive obstructive jaundice, and weight loss to our emergency department. Abdominal ultrasound showed a dilatation of the biliary ducts due to pathologically enlarged lymph nodes of the hepatic hilum. A complete clinical and radiologic assessment to discover the primary tumor was negative except for pulmonary metastasis. In the laboratory findings at admission there were signs of cholestasis with an abnormal increase in the rate of testicular tumor markers (serum beta-human chorionic gonadotropin level was 11,000IU/ml), which subsequently led to the suspicion of a testicular tumor. Further evaluation included testicular palpation and ultrasound which revealed a testicular nodule. The patient underwent an inguinal orchidectomy of the right testis and histopathological examination confirmed a pure choriocarcinoma. The prognosis was poor due to lymph node involvement at the hepatic hilum. He died one month later, despite general chemotherapy., Conclusions: The clinical presentation of the disease and the rarity of this entity are two remarkable characteristics described in this case report which are rarely reported in literature.
- Published
- 2012
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50. Abscess of urachal remnants presenting with acute abdomen: a case series.
- Author
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Tazi F, Ahsaini M, Khalouk A, Mellas S, Stuurman-Wieringa RE, Elfassi MJ, and Farih MH
- Abstract
Introduction: Urachal diseases are rare and may develop from a congenital anomaly in which a persistent or partial reopening of the fetal communication between the bladder and the umbilicus persists. The most frequently reported urachal anomalies in adults are infected urachal cyst and urachal carcinoma. The diagnosis of this entity is not always easy because of the rarity of these diseases and the atypical symptoms at presentation. Imaging techniques, such as ultrasonography and computed tomography have a significant role in recognizing the presence of urachus-derived lesions., Cases Presentations: Case presentation 1: A 25-year-old Arab-Berber man presented with a 10-day history of progressive lower abdominal pain accompanied by fever, vomiting, and low urinary tract symptoms to our emergency department. Laboratory data revealed leucocytosis. The diagnosis of an acute peritonitis was made initially. Abdominal ultrasonography revealed a hypoechoic tract from the umbilicus to the abdominal wall, and the diagnosis was rectified (infected urachal remnants). The patient was initially treated with intravenous antibiotics in combination with a percutaneous drainage. Afterwards an extraperitoneal excision of the urachal remnant including a cuff of bladder was performed. The histological analysis did not reveal a tumor of the urachal remnant. Follow-up examinations a few months later showed no abnormality.Case presentation 2: A 35-year-old Arab-Berber man, without prior medical history with one week of abdominal pain, nausea and vomiting, associated with fever but without lower urinary tract symptoms visited our emergency department. Laboratory data revealed leucocytosis. Abdominal ultrasonography was not conclusive. Computed tomography of the abdomen was the key to the investigation and the diagnosis of an abscess of urachal remnants was made. The patient underwent the same choice of medical-surgical treatment as previously described for case one, with a good follow-up result.Case presentation 3: A 22-year-old Arab-Berber man, with no relevant past medical history, presented to our emergency department because of suspected acute surgical abdomen. Physical examination revealed umbilical discharge with erythema and a tender umbilical mass. Abdominal ultrasonography and computed tomography scan confirmed the diagnosis of infected urachal sinus. Initial management was intravenous antibiotics associated with a percutaneous drainage with a good post-operative result, but a few days later, he was readmitted with the same complaint and the decision was made for surgical treatment consisting of excision of the infected urachal sinus. The clinical course was uneventful. Histological examination did not reveal any signs of malignancy., Conclusions: We describe our clinical observations and an analysis of the existing literature to present the various clinical, radiological, pathological and therapeutic aspects of an abscess of urachal remnants. To the best of our knowledge, this manuscript is an original case report because this atypical presentation is rarely reported in the literature and only a few cases have been described.
- Published
- 2012
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