17 results on '"Fang Yuan-min"'
Search Results
2. Evaluation of reclamation land productivity in mining districts
- Author
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WU, Xue-qun, ZUO, Xiao-qing, and FANG, Yuan-min
- Published
- 2011
- Full Text
- View/download PDF
3. Real-time emergency route generating algorithm in tunnel
- Author
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FANG, Yuan-min, CHEN, Jie, AI, Chun-long, ZHANG, Chun-liang, ZHOU, Shi-yong, FU, Xia-jiang, and GU, De-mao
- Published
- 2011
- Full Text
- View/download PDF
4. High glucose forces a positive feedback loop connecting ErbB4 expression and mTOR/S6K pathway to aggravate the formation of tau hyperphosphorylation in differentiated SH-SY5Y cells
- Author
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Zhi-Jie Dai, Liang-Yan Wu, Xia-Jie Shi, Zi Chen, Shan-Lei Zhou, Sheng-Dan Nie, Jiajia Liu, Shan Wang, Can-E. Tang, Jing Wu, Jiao Zheng, Tao Song, Xin Li, and Fang-yuan Min
- Subjects
Male ,0301 basic medicine ,Aging ,Receptor, ErbB-4 ,SH-SY5Y ,Gene Expression ,tau Proteins ,P70-S6 Kinase 1 ,Hippocampal formation ,Receptor tyrosine kinase ,Rats, Sprague-Dawley ,03 medical and health sciences ,0302 clinical medicine ,Downregulation and upregulation ,Diabetes Mellitus ,medicine ,Animals ,Cognitive Dysfunction ,Phosphorylation ,Cells, Cultured ,PI3K/AKT/mTOR pathway ,ERBB4 ,Feedback, Physiological ,Neurons ,biology ,Chemistry ,TOR Serine-Threonine Kinases ,General Neuroscience ,Neurodegeneration ,medicine.disease ,Cell biology ,Glucose ,030104 developmental biology ,Hyperglycemia ,biology.protein ,Neurology (clinical) ,Geriatrics and Gerontology ,030217 neurology & neurosurgery ,Signal Transduction ,Developmental Biology - Abstract
High glucose (HG)-induced mammalian target of rapamycin (mTOR) overactivation acts as a signaling hub for the formation of tau hyperphosphorylation, which contributes to the development of diabetes-associated cognitive deficit. How HG induces the sustained activation of mTOR in neurons is not clearly understood. ErbB4, a member of the receptor tyrosine kinase family, plays critical roles in development and function of neural circuitry, relevant to behavioral deficits. Here, we showed HG-induced ErbB4 overexpression in differentiated SH-SY5Y cells and primary hippocampal neurons and hippocampal pyramidal neurons of streptozotocin-induced diabetic rats. Inhibition of ErbB4 signaling prevented the HG-induced activation of mTOR/S6K signaling to suppress tau hyperphosphorylation. In contrast, ErbB4 overexpression increased the activation of mTOR/S6K signaling, resulting in tau hyperphosphorylation similar to HG treatment. We also demonstrated that HG upregulated the expression of ErbB4 at a mTOR-dependent posttranscriptional level. Together, our results provide the first evidence for the presence of a positive feedback loop for the sustained activation of mTOR involving overexpressed ErbB4, leading to the formation of tau hyperphosphorylation under HG condition. Therefore, ErbB4 is a potential therapeutic target for diabetes-associated neurodegeneration.
- Published
- 2018
5. 3S-Based Farmland Information Support System at County Level
- Author
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Zuo Xiao-qing, Fang Yuan-min, and Wu Xuequn
- Subjects
ComputingMilieux_GENERAL ,Geography ,Geographic information system ,Work (electrical) ,business.industry ,Agriculture ,Environmental resource management ,Global Positioning System ,Information support ,Chinese agriculture ,County level ,China ,business - Abstract
In china, with the development of GPS, GIS, RS, 3S technology is gradually used in the agriculture in recent years. This paper introduced the concepts of GPS, GIS, RS. Considering the fact of the Chinese agriculture, we developed the farmland information support system based on the integration of GPS, GIS, RS. With the application of this system in some counties of Yunnan province, the work mode of the department of the agriculture has started to be changed.
- Published
- 2010
6. Error Analysis and Calibration of 3D Laser Scanner in Surveying in Finished Stopes
- Author
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Chen Jie, Zuo Xiao-qing, Xia Yonghua, Yang Xiang-ying, and Fang Yuan-min
- Subjects
Observational error ,Data acquisition ,Laser scanning ,Computer science ,Orientation (computer vision) ,Calibration ,Mechanical engineering ,Geodetic datum ,Roof ,Reliability (statistics) - Abstract
Considering the hidden danger in the finished stopes in underground metal mines in China, a new cavity data acquisition method based on 3D laser scanning technology is proposed in Dahongshan mine district. This technology uses contactless measurement mode, by which not only the geometric parameter of cavity such as length, area, volume, deformation of roof and wall rock can be gained accurately, but also the security and efficiency of cavity data acquisition are greatly raised. It provides relatively reliable datum for the safety evaluation and the control of emptied stopes as well as the design of ore column stopping. There is certain particularity in application method of 3D laser scanning technology for the finished stopes in mine. For the sake of enhancing the precision and reliability of obtained datum, in this paper, based on systematic analysis of measurement errors of CMS, the key systematic errors of side rolling, pitching and orientation were discussed in detail, and the corresponding calibration method was put forward.
- Published
- 2009
7. Researches on the Evaluation of the Farmland Productivity at County Level Based on GIS
- Author
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Zuo Xiao-qing, Fang Yuan-min, and Wu Xuequn
- Subjects
Geographic information system ,Soil test ,business.industry ,Delphi method ,Land management ,Analytic hierarchy process ,Agricultural engineering ,Agricultural productivity ,business ,Productivity ,Field (geography) ,Mathematics - Abstract
With the development of the project of Formula Fertilization by Soil Testing in china,in order to investigate the soil condition,fertility level,nutrients status,soil degeneration status and the farmland integrated productivity of china,the government decided to start up the project of the Evaluation of the farmland productivity with the field investigation data and the analysis assay data, which were got in the project of Formula Fertilization by Soil Testing. Based on the spatial analysis function of the geographic information system(GIS), such as overlay analysis and spatial interpolation,using soil image,Present land use map and administrative map of the poroject area?this research decided evaluation unit and connected the field investigation data and the analysis assay data. Considering the actual conditions of the poroject area, the experts selected Sixteen affected factors from four aspects as land management?land growing situation?profile situation and soil nutrient content?and the evaluation system of farmland fertility of was built up?Aimed at the affected factors,It adopts the Delphi method to identify the membership function of severa1 affected factors and introduces Analytica1 Hierarch process (AHP) to calculate the weight of evaluating factors.On the basis of these datas,this research used the Additive Model to calculate the Integrated Fertility Index(IFI) and also analyses its space distribution?Because The results are in 1ine with the local situation of the city,This result can be applied to agricultural production.
- Published
- 2009
8. Application and Research on ArcSDE-Based Spatial Data Version Management
- Author
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Fang Yuan-min, Zuo Xiao-qing, and Wu Xuequn
- Subjects
Geographic information system ,Visual Basic ,Database ,business.industry ,ArcObjects ,Computer science ,Parallel algorithm ,Application software ,computer.software_genre ,Component (UML) ,Graphics ,business ,Spatial analysis ,computer ,computer.programming_language - Abstract
Parallel editing of spatial data is one of the concern focuses in GIS research. The paper firstly discusses current status of research and analyzes mechanism and implement method of ArcSDE version management. With ArcObjects component as exploitation platform and Visual Basic as tools, a version management component is designed and developed and integrated into application software which implements multi-users parallel editing and version management of spatial data.
- Published
- 2009
9. Scale effect of Li-Xiang Railway construction impact on landscape pattern and its ecological risk.
- Author
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WANG De-zhi, QIU Peng-hua, and FANG Yuan-min
- Abstract
As a large corridor project, plateau railway has multiple points and passes various sensitive environments along the railway. The determination of the scope of impact on ecological environment from railway construction is often controversial in ecological impact assessment work. Taking the Tangbu-Jiantang section of Li-Xiang Railway as study object, and using present land use map (1:10000) in 2012 and DEM as data sources, corridor cutting degree index (CCI) and cumulative effect index of corridor (CCEI) were established by topology, buffer zone and landscape metrics methods. Besides, the ecological risk index used for railway construction was improved. By quantitative analysis of characteristics of the spatiotemporal change of landscape pattern and its evolution style at different spatial scales before and after railway construction, the most appropriate evaluation scale of the railway was obtained. Then the characteristics of the spatio-temporal variation of ecological risk within this scale before and after railway construction were analyzed. The results indicated that the cutting model and degree of railway corridor to various landscape types could be effectively reflected by CCI, and the exposure and harm relations between risk sources and risk receptors of railway can be measured by CCEI. After the railway construction, the railway corridor would cause a great deal of middle cutting effect on the landscape along the railroad, which would influence wood land and grassland landscape most greatly, while would cause less effect of edge cutting and internal cutting. Landscape indices within the 600 m buffer zone demonstrated the most obvious scale effect, therefore, the 600 m zone of the railway was set as the most suitable range of ecological impact assessment. Before railway construction, the low ecological risk level covered the biggest part of the 600 m assessment zone. However, after the railway construction, the ecological risk increased significantly, and the most part of the study area was at the moderate ecological risk level. The ecological risk presented ring-shaped and multi-kernel patterns, and was lower in the southern part than in the northern part of the study area. [ABSTRACT FROM AUTHOR]
- Published
- 2015
10. A spatial indexing approach based on linear referencing system
- Author
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Zuo, Xiao qing, primary and Fang, Yuan min, additional
- Published
- 2006
- Full Text
- View/download PDF
11. Error Analysis and Calibration of 3D Laser Scanner in Surveying in Finished Stopes.
- Author
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Xia yong-hua, Fang Yuan-min, Yang Xiang-ying, Chen Jie, and Zuo Xiao-qing
- Published
- 2009
- Full Text
- View/download PDF
12. A spatial indexing approach based on linear referencing system.
- Author
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Zuo, Xiao qing and Fang, Yuan min
- Published
- 2006
- Full Text
- View/download PDF
13. Methods for mineral resources assessment based on GIS in Gejiu.
- Author
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Zhu Da-Ming, Fang Yuan-Min., Zhu Da-Ming, and Fang Yuan-Min.
- Abstract
A review is presented of the use of geographic information systems (GIS) for the integrated analysis of geoscience information for mineral resource assessment. GIS was applied in the Gejiu, China, tin mine region. The mine has a long exploitation history but resources are nearly depleted. Application of GIS indicated the presence of new reserves of Cu and Sn totalling 30 000 t., A review is presented of the use of geographic information systems (GIS) for the integrated analysis of geoscience information for mineral resource assessment. GIS was applied in the Gejiu, China, tin mine region. The mine has a long exploitation history but resources are nearly depleted. Application of GIS indicated the presence of new reserves of Cu and Sn totalling 30 000 t.
14. Evaluation of reclamation land productivity in mining districts.
- Author
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Wu Xue-Qun, Fang Yuan-Min., Zuo Xiao-Qing, Wu Xue-Qun, Fang Yuan-Min., and Zuo Xiao-Qing
- Abstract
Field studies and a spatial information method were used to evaluate the productivity of reclaimed areas based on evaluation factors including climate, site condition, profile shape, physical and chemical properties of the soil, nutrient status and soil management. Remote sensing, a global positioning system and a geographic information system were employed to generate an evaluation unit map for each land area. The membership grade for each factor was determined using a fuzzy logic approach and the combined weight of each factor obtained based on an analytical hierarchy process and the Delphi method. An integrated fertility index (IFI) reflecting the productivity of the reclaimed land areas was calculated for each area of land based on membership grades and the combined weights of all factors. Experimental data showed that the spatial information technique is an efficient method for field data collection, and quantitative analysis showed that the IFI is appropriate for describing the productivity of reclaimed land., Field studies and a spatial information method were used to evaluate the productivity of reclaimed areas based on evaluation factors including climate, site condition, profile shape, physical and chemical properties of the soil, nutrient status and soil management. Remote sensing, a global positioning system and a geographic information system were employed to generate an evaluation unit map for each land area. The membership grade for each factor was determined using a fuzzy logic approach and the combined weight of each factor obtained based on an analytical hierarchy process and the Delphi method. An integrated fertility index (IFI) reflecting the productivity of the reclaimed land areas was calculated for each area of land based on membership grades and the combined weights of all factors. Experimental data showed that the spatial information technique is an efficient method for field data collection, and quantitative analysis showed that the IFI is appropriate for describing the productivity of reclaimed land.
15. 3D visualisation model and key techniques for digital mine.
- Author
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Jin Bao-Xuan, Fang Yuan-Min, Song Wei-Wei., Jin Bao-Xuan, Fang Yuan-Min, and Song Wei-Wei.
- Abstract
An integrated above-ground and underground visualisation framework model was developed based on entities in a mine database such as the orebody, rock body, well tube, tunnel and goaf. A mixed model was then used to take into account irregularities and non-uniformity in the entities and their dynamics in which 3D expressions of the entities were obtained. A case study is presented for the Yunnan Cu mine in China where 3D spatial data for the mine surface were collected including DEM, DOM and the buildings and roads in the mine. A spatial database of the mine was developed based on underground data including part of the orebody, tunnels and auxiliary facilities. The mixed modelling method was used to build 3D models of the orebodies and tunnels. A 3D visualisation system for the digital mine was developed to provide a scientific basis for the exploitation of the mine., An integrated above-ground and underground visualisation framework model was developed based on entities in a mine database such as the orebody, rock body, well tube, tunnel and goaf. A mixed model was then used to take into account irregularities and non-uniformity in the entities and their dynamics in which 3D expressions of the entities were obtained. A case study is presented for the Yunnan Cu mine in China where 3D spatial data for the mine surface were collected including DEM, DOM and the buildings and roads in the mine. A spatial database of the mine was developed based on underground data including part of the orebody, tunnels and auxiliary facilities. The mixed modelling method was used to build 3D models of the orebodies and tunnels. A 3D visualisation system for the digital mine was developed to provide a scientific basis for the exploitation of the mine.
16. Real-time emergency route generating algorithm in tunnel.
- Author
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Fang Yuan-Min, Ai Chun-Long, Chen Jie, Fu Xia-Jiang, Gu De-Mao., Zhang Chun-Liang, Zhou Shi-Yong, Fang Yuan-Min, Ai Chun-Long, Chen Jie, Fu Xia-Jiang, Gu De-Mao., Zhang Chun-Liang, and Zhou Shi-Yong
- Abstract
The algorithm was developed for a large metal mine as part of a digital mine system. The tunnel is mathematically described using the centreline model and pre-processing of the centrelines is carried out to eliminate interference in the source data. Mine shafts and shafts with steep slopes are eliminated during pre-processing, while the interface is preserved for point-like objects such as blowers and directions such as the wind direction from blowers. The final algorithm is optimised by a filter method so that the calculation is only performed at the end- and hub-points and the amount of data to be processed in the algorithm is reduced., The algorithm was developed for a large metal mine as part of a digital mine system. The tunnel is mathematically described using the centreline model and pre-processing of the centrelines is carried out to eliminate interference in the source data. Mine shafts and shafts with steep slopes are eliminated during pre-processing, while the interface is preserved for point-like objects such as blowers and directions such as the wind direction from blowers. The final algorithm is optimised by a filter method so that the calculation is only performed at the end- and hub-points and the amount of data to be processed in the algorithm is reduced.
17. [Scale effect of Li-Xiang Railway construction impact on landscape pattern and its ecological risk].
- Author
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Wang DZ, Qiu PH, and Fang YM
- Subjects
- China, Conservation of Natural Resources, Ecology, Models, Theoretical, Spatio-Temporal Analysis, Environment, Railroads, Risk Assessment
- Abstract
As a large corridor project, plateau railway has multiple points and passes various sensitive environments along the railway. The determination of the scope of impact on ecological environment from railway construction is often controversial in ecological impact assessment work. Taking the Tangbu-Jiantang section of Li-Xiang Railway as study object, and using present land use map (1:10000) in 2012 and DEM as data sources, corridor cutting degree index ( CCI) and cumulative effect index of corridor (CCEI) were established by topology, buffer zone and landscape metrics methods. Besides, the ecological risk index used for railway construction was improved. By quantitative analysis of characteristics of the spatio-temporal change of landscape pattern and its evolution style at different spatial scales before and after railway construction, the most appropriate evaluation scale of the railway was obtained. Then the characteristics of the spatio-temporal variation of ecological risk within this scale before and after railway construction were analyzed. The results indicated that the cutting model and degree of railway corridor to various landscape types could be effectively reflected by CCI, and the exposure and harm relations between risk sources and risk receptors of railway can be measured by CCEI. After the railway construction, the railway corridor would cause a great deal of middle cutting effect on the landscape along the railroad, which would influence wood land and grassland landscape most greatly, while would cause less effect of edge cutting and internal cutting. Landscape indices within the 600 m buffer zone demonstrated the most obvious scale effect, therefore, the 600 m zone of the railway was set as the most suitable range of ecological impact assessment. Before railway construction, the low ecological risk level covered the biggest part of the 600 m assessment zone. However, after the railway construction, the ecological risk increased significantly, and the most part of the study area was at the moderate ecological risk level. The ecological risk presented ring-shaped and multi-kernel patterns, and was lower in the southern part than in the northern part of the study area.
- Published
- 2015
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