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279 results on '"Fan, Zhongqi"'

3. Research on data trust model and technical architecture of intelligent mines based on blockchain technology

Author

FAN Zhongqi and DAI Lin

Subjects
intelligent mine, blockchain technology, data trust, data management, Engineering geology. Rock mechanics. Soil mechanics. Underground construction, TA703-712, Mining engineering. Metallurgy, TN1-997
Abstract

China's intelligent mine construction is still in the early stage of development, which is seriously constrained by data trust problems such as low credibility of mine data, lack of trust mechanism in the data sharing process and the risk of data security and privacy leakage.To this end, this paper proposes an intelligent mine data trust model by drawing on the holistic approach to national security.Specifically, this study 1) offered a working definition of this model and proposed its underlying conceptions; 2) designed its technical architecture and analyzed the core technologies involved; 3) proposed the implementation strategies of the intelligent mine data trust model based on blockchain technology.This may lay the foundation for blockchain technology to empower intelligent mines and comprehensively enhance its efficiency and productivity, thus promoting the high-quality development of the coal industry.

Published
2024
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19. The impact of transformation policies on the resilience of mining resource-based cities

Author

Fan Zhongqi and Liu Qiyuan

Subjects
mining resource-based cities, transformation policies, urban resilience, policy evaluation, psm-did, Engineering geology. Rock mechanics. Soil mechanics. Underground construction, TA703-712, Mining engineering. Metallurgy, TN1-997
Abstract

Problems like a lack of diverse industries, environmental degradation and major social risks can lead to low resilience in resource-based cities.As part of a broader strategy to achieve high quality development, it therefore remains imperative to objectively assess the effects of transformation policies on the resilience of these cities.This will help to minimize urban risks and fill gaps in policy making.Based on the panel data of 278 prefecture-level cities from 2006 to 2020, this study proposed a two-way panel fixed-effects model using the PSM-DID method to examine the impact of the National Plan for Sustainable Development of Resource-based Cities(2013-2020) on urban resilience in promoting the transformation of resource-based cities.Through the present empirical analysis, we found that: the Plan does have a significant role to play in boosting urban resilience, but there is a policy lag; the mechanism analysis shows that the Plan raises urban resilience level mainly through optimizing industrial structure and improving housing conditions; the heterogeneity analysis shows that there are significant differences in the policy effects on different types of resource-based cities, among which declining resource-based cities exhibit the most significant improvement in their urban resilience.

Published
2023
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27. Re-evaluation of the nor mutation and the role of the NAC-NOR transcription factor in tomato fruit ripening

Author

Gao, Ying, Wei, Wei, Fan, Zhongqi, Zhao, Xiaodan, Zhang, Yiping, Jing, Yuan, Zhu, Benzhong, Zhu, Hongliang, Shan, Wei, Chen, Jianye, Grierson, Donald, Luo, Yunbo, Jemrić, Tomislav, Jiang, Cai-Zhong, and Fu, Da-Qi

Subjects
Agricultural, Veterinary and Food Sciences, Horticultural Production, Genetics, Ethylenes, Fruit, Gene Expression Regulation, Plant, Solanum lycopersicum, Mutation, Plant Proteins, Transcription Factors, CRISPR/Cas9, gene function, NAC-NOR, nor mutant, tomato fruit ripening, transcription factor, NAC-NOR, nor mutant, Plant Biology, Crop and Pasture Production, Plant Biology & Botany, Crop and pasture production, Biochemistry and cell biology, Plant biology
Abstract

The tomato non-ripening (nor) mutant generates a truncated 186-amino-acid protein (NOR186) and has been demonstrated previously to be a gain-of-function mutant. Here, we provide more evidence to support this view and answer the open question of whether the NAC-NOR gene is important in fruit ripening. Overexpression of NAC-NOR in the nor mutant did not restore the full ripening phenotype. Further analysis showed that the truncated NOR186 protein is located in the nucleus and binds to but does not activate the promoters of 1-aminocyclopropane-1-carboxylic acid synthase2 (SlACS2), geranylgeranyl diphosphate synthase2 (SlGgpps2), and pectate lyase (SlPL), which are involved in ethylene biosynthesis, carotenoid accumulation, and fruit softening, respectively. The activation of the promoters by the wild-type NOR protein can be inhibited by the mutant NOR186 protein. On the other hand, ethylene synthesis, carotenoid accumulation, and fruit softening were significantly inhibited in CR-NOR (CRISPR/Cas9-edited NAC-NOR) fruit compared with the wild-type, but much less severely affected than in the nor mutant, while they were accelerated in OE-NOR (overexpressed NAC-NOR) fruit. These data further indicated that nor is a gain-of-function mutation and NAC-NOR plays a significant role in ripening of wild-type fruit.

Published
2020

33. A NAC transcription factor, NOR-like1, is a new positive regulator of tomato fruit ripening

Author

Gao, Ying, Wei, Wei, Zhao, Xiaodan, Tan, Xiaoli, Fan, Zhongqi, Zhang, Yiping, Jing, Yuan, Meng, Lanhuan, Zhu, Benzhong, Zhu, Hongliang, Chen, Jianye, Jiang, Cai-Zhong, Grierson, Donald, Luo, Yunbo, and Fu, Da-Qi

Subjects
Biotechnology, Genetics, Aetiology, 2.1 Biological and endogenous factors
Abstract

Ripening of the model fruit tomato (Solanum lycopersicum) is controlled by a transcription factor network including NAC (NAM, ATAF1/2, and CUC2) domain proteins such as No-ripening (NOR), SlNAC1, and SlNAC4, but very little is known about the NAC targets or how they regulate ripening. Here, we conducted a systematic search of fruit-expressed NAC genes and showed that silencing NOR-like1 (Solyc07g063420) using virus-induced gene silencing (VIGS) inhibited specific aspects of ripening. Ripening initiation was delayed by 14 days when NOR-like1 function was inactivated by CRISPR/Cas9 and fruits showed obviously reduced ethylene production, retarded softening and chlorophyll loss, and reduced lycopene accumulation. RNA-sequencing profiling and gene promoter analysis suggested that genes involved in ethylene biosynthesis (SlACS2, SlACS4), color formation (SlGgpps2, SlSGR1), and cell wall metabolism (SlPG2a, SlPL, SlCEL2, and SlEXP1) are direct targets of NOR-like1. Electrophoretic mobility shift assays (EMSA), chromatin immunoprecipitation-quantitative PCR (ChIP-qPCR), and dual-luciferase reporter assay (DLR) confirmed that NOR-like1 bound to the promoters of these genes both in vitro and in vivo, and activated their expression. Our findings demonstrate that NOR-like1 is a new positive regulator of tomato fruit ripening, with an important role in the transcriptional regulatory network.

Published
2018

48. T proliferating cells derived autophagy signature associated with prognosis and immunotherapy resistance in a pan-cancer analysis

Author

Fan, Zhongqi, primary, Liu, Yutao, additional, Li, Chengcheng, additional, Jiang, Yanfang, additional, Wang, Nanya, additional, Wang, Mingda, additional, Li, Chao, additional, Diao, Yongkang, additional, Qiu, Wei, additional, Zhu, Xin, additional, Wang, Guoqiang, additional, Cai, Shangli, additional, Yang, Tian, additional, and Lv, Guoyue, additional

Published
2023
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50. Comprehensive metabolome and transcriptome analyses demonstrate divergent anthocyanin and carotenoid accumulation in fruits of wild and cultivated loquats

Author

Su, Wenbing, primary, Zhu, Changqing, additional, Fan, Zhongqi, additional, Huang, Mingkun, additional, Lin, Han, additional, Chen, Xiuping, additional, Deng, Chaojun, additional, Chen, Yongping, additional, Kou, Yidan, additional, Tong, Zhihong, additional, Zhang, Yaling, additional, Xu, Changjie, additional, Zheng, Shaoquan, additional, and Jiang, Jimou, additional

Published
2023
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