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Your search keyword '"Fan, Tongtong"' showing total 11 results
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11 results on '"Fan, Tongtong"'

10. Genome sequencing, assembly, and characterization of Pichia fermentansZ9Y-3 as a non-Saccharomycesyeast with aroma enhancing potential

Author

Fan, Tongtong, Qu, Jianing, Wang, Lu, Zhang, Jiarui, Yang, Xiaobing, Zhang, Hongyan, Qin, Yi, Tao, Yongsheng, and Jin, Guojie

Abstract

Pichia fermentansis an important non-Saccharomycesyeast applied in mixed fermentation to enhance fruity and floral traits of wine aroma. In this study, genome sequencing of P. fermentansZ9Y-3 was performed using the PacBio single-molecule real-time sequencing platform, and was further assembled using MECAT. The sequenced genes are annotated by non-redundant protein (Nr), Gene Ontology (GO), Cluster of Orthologous Groups of proteins (COG), Kyoto Encyclopedia of Genes and Genomes (KEGG) and carbohydrate-active enzymes (CAZymes) database. Results indicated that the genome size was about 13.5 Mb with 42.09% GC content and 4730 protein coding genes. The 95.90% genes were annotated to the non-redundant protein (Nr) database, and then annotated to GO database. The 62.64% genes annotated to the COG database revealed 25 functional groups. The 58.22% genes annotated to the KEGG database revealed 5 groups. The 586 genes were annotated to CAZymes, in which two genes bglHand bglCencoding beta-glucosidase were found and further analyzed its motifs. A terpene and a nonribosomal peptides like secondary metabolic gene clusters were predicted using antiSMASH 7.0.0. This study benefits us to understand physiological and biochemical behavior of P. fermentansZ9Y-3 at a molecular level to better use P. fermentansZ9Y-3 in aroma enhancing winemaking.

Published
2023
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11. Reinforced pain catastrophizing during menstrual phase among women with primary dysmenorrhea is mediated by cerebral blood flow in the medial prefrontal cortex.

Author

Shang, Meiling, Liu, Huiping, Ma, Ling, Fan, Tongtong, Bai, Weixian, Yang, Jing, Quan, Lu, Zhang, Yuchen, and Dun, Wanghuan

Subjects
*PAIN catastrophizing, *MCGILL Pain Questionnaire, *CHILDBEARING age, *FRONTAL lobe, *PREFRONTAL cortex
Abstract

Pain catastrophizing is a prominent psychological factor that is strongly correlated with pain. Although the complex properties of pain catastrophizing vary across different pain phases, the contribution of chronic pain to its progression from a general trait to a higher state remains unclear. This study aimed to examine the neural mechanisms and degree to which pain catastrophizing is reinforced in the context of primary dysmenorrhea (PDM), one of the most prevalent gynaecological complaints experienced by women of reproductive age. Altogether, 29 women with moderate‐to‐severe PDM were included in this study. Arterial spin labelling was used to quantify the cerebral blood flow (CBF) in each participant in both the pain‐free and painful phases. The pain catastrophizing scale (PCS) was completed in two phases, and the Short‐Form McGill Pain Questionnaire was completed in the painful phase. Compared with pain catastrophizing in the pain‐free phase (PCSpf), pain catastrophizing in the painful phase (PCSp) is higher and positively correlated with the composite factor of menstrual pain. CBF analysis indicated that the PCSp is positively associated with CBF in the frontal cortex, hippocampus and amygdala. The reinforcement of pain catastrophizing correlates with CBF in the prefrontal cortex. Specifically, the medial prefrontal cortex, which correlates with pain state, plays a crucial role in mediating the reinforcing effect of pain in the PCSp. These results promote the mechanical comprehension of pain catastrophizing management in individuals with chronic pain. [ABSTRACT FROM AUTHOR]

Published
2024
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