20 results on '"Fan, Quan-chun"'
Search Results
2. Long‐term spaceflight composite stress induces depressive behaviors in model rats through disrupting hippocampus synaptic plasticity.
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Yin, Yi‐Shu, Zhu, Yuan‐Bing, Liu, Jun‐Lian, Fan, Quan‐Chun, Wu, Xiao‐Rui, Zhao, Shuang, Wang, Jia‐Ping, Liu, Yu, Li, Yong‐Zhi, and Lu, Wei‐Hong
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NEUROPLASTICITY ,SPACE flight ,CENTRAL nervous system ,HIPPOCAMPUS (Brain) ,WEIGHT loss ,IMMOBILIZATION stress - Abstract
Introduction: Long‐term spaceflight composite stress (LSCS) can cause adverse effects on human systems, including the central nervous system, which could trigger anxiety and depression. Aims: This study aimed to identify changes in hippocampus synaptic plasticity under LSCS. Methods: The present study simulated the real long‐term space station environment by conducting a 42‐day experiment that involved simulating microgravity, isolation, noise, circadian rhythm disruptions, and low pressure. The mood and behavior of the rats were assessed by behavior test. Transmission electron microscopy and patch‐clamp were used to detect the changes in synapse morphology and electrophysiology, and finally, the expression of NMDA receptor channel proteins was detected by western blotting. Results: The results showed that significant weight loss, anxiety, and depressive behaviors in rats were observed after being exposed to LSCS environment for 42 days. The synaptic structure was severely damaged, manifested as an obvious decrease in postsynaptic density thickness and synaptic interface curvature (p < 0.05; p < 0.05, respectively). Meanwhile, LTP was significantly impaired (p < 0.0001), and currents in the NMDAR channel were also significantly reduced (p < 0.0001). Further analysis found that LSCS decreased the expression of two key subtype proteins on this channel. Conclusion: These results suggested that LSCS‐induced depressive behaviors by impairing synaptic plasticity in rat hippocampus. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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3. Long‐term spaceflight composite stress induces depressive behaviors in model rats through disrupting hippocampus synaptic plasticity
- Author
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Yin, Yi‐Shu, primary, Zhu, Yuan‐Bing, additional, Liu, Jun‐Lian, additional, Fan, Quan‐Chun, additional, Wu, Xiao‐Rui, additional, Zhao, Shuang, additional, Wang, Jia‐Ping, additional, Liu, Yu, additional, Li, Yong‐Zhi, additional, and Lu, Wei‐Hong, additional
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- 2023
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4. Evaluation of the health status of six volunteers from the Mars 500 project using pulse analysis
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Shi, Hong-zhi, Fan, Quan-chun, Gao, Jian-yi, Liu, Jun-lian, Bai, Gui-e, Mi, Tao, Zhao, Shuang, Liu, Yu, Xu, Dong, Guo, Zhi-feng, and Li, Yong-zhi
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- 2017
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5. Impact of 60 Days of 6° head down bed rest on cardiopulmonary function, and the effects of Taikong Yangxin Prescription (太空养心方) as a countermeasure
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Shi, Hong-zhi / 石宏志, Li, Yong-zhi / 李勇枝, Tang, Zhi-zhong / 唐志忠, Zhong, Chong-fa / 仲崇发, Fan, Quan-chun / 范全春, Gao, Jian-yi / 高建义, Liu, Jun-lian / 刘军莲, Mi, Tao / 米 涛, Zhao, Shuang / 赵 爽, and Li, Ying-hui / 李莹辉
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- 2014
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6. Syndrome Differentiation of Chinese Medicine in Mars 500 Long-Term Closed Environment
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Shi, Hong-zhi, primary, Fan, Quan-chun, additional, Bai, Gui-e, additional, Gao, Jian-yi, additional, Liu, Jun-lian, additional, Mi, Tao, additional, Zhao, Shuang, additional, Liu, Yu, additional, Guo, Li-guo, additional, Xu, Dong, additional, Li, Yong-zhi, additional, and Chen, Kai-xian, additional
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- 2019
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7. Evaluation of the health status of six volunteers from the Mars 500 project using pulse analysis
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Shi, Hong-zhi, primary, Fan, Quan-chun, additional, Gao, Jian-yi, additional, Liu, Jun-lian, additional, Bai, Gui-e, additional, Mi, Tao, additional, Zhao, Shuang, additional, Liu, Yu, additional, Xu, Dong, additional, Guo, Zhi-feng, additional, and Li, Yong-zhi, additional
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- 2016
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8. Syndrome Differentiation Analysis on Mars500 Data of Traditional Chinese Medicine
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Li, Yong-Zhi, primary, Li, Guo-Zheng, additional, Gao, Jian-Yi, additional, Zhang, Zhi-Feng, additional, Fan, Quan-Chun, additional, Xu, Jia-Tuo, additional, Bai, Gui-E, additional, Chen, Kai-Xian, additional, Shi, Hong-Zhi, additional, Sun, Sheng, additional, Liu, Yu, additional, Shao, Feng-Feng, additional, Mi, Tao, additional, Jia, Xin-Hong, additional, Zhao, Shuang, additional, Chen, Jia-Chang, additional, Liu, Jun-Lian, additional, Guo, Yu-Meng, additional, and Tu, Li Ping, additional
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- 2015
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9. Effects of L. F04, the Active Fraction of Lycopus Lucidus, on Erythrocytes Rheological Property.
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Shi Hong-zhi, Gao Nan-nan, Li Yong-zhi, Yu Jing-guang, Fan Quan-chun, Bai Gui-e, and Xin Bing-mu
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HERBAL medicine ,ERYTHROCYTES ,BLOOD coagulation ,THROMBOSIS ,SCIENTIFIC apparatus & instruments ,LABORATORY rats - Abstract
The article presents the findings of an experimental work and research on the effects of L. F04, the active fraction of the herb Lycopus lucidus, on erythrocytes rheological property, conducted by Shi Hong-zhi, Li Yong-zhi et al. Lycopus lucidus has effects in resisting coagulation and thrombosis. Cell rheology detector type LG-B-190 manufactured by Shidi Scientific Instrument Co. is one of the instruments used in the study. After being injected with dextran 500, rats in the model group showed characteristics of blood stasis.
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- 2005
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10. Syndrome Differentiation Analysis on Mars500 Data of Traditional Chinese Medicine.
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Li YZ, Li GZ, Gao JY, Zhang ZF, Fan QC, Xu JT, Bai GE, Chen KX, Shi HZ, Sun S, Liu Y, Shao FF, Mi T, Jia XH, Zhao S, Chen JC, Liu JL, Guo YM, and Tu LP
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- Algorithms, Humans, Models, Biological, Syndrome, Medicine, Chinese Traditional, Spacecraft
- Abstract
Mars500 study was a psychological and physiological isolation experiment conducted by Russia, the European Space Agency, and China, in preparation for an unspecified future manned spaceflight to the planet Mars. Its intention was to yield valuable psychological and medical data on the effects of the planned long-term deep space mission. In this paper, we present data mining methods to mine medical data collected from the crew consisting of six spaceman volunteers. The synthesis of the four diagnostic methods of TCM, inspection, listening, inquiry, and palpation, is used in our syndrome differentiation. We adopt statistics method to describe the syndrome factor regular pattern of spaceman volunteers. Hybrid optimization based multilabel (HOML) is used as feature selection method and multilabel k-nearest neighbors (ML-KNN) is applied. According to the syndrome factor statistical result, we find that qi deficiency is a base syndrome pattern throughout the entire experiment process and, at the same time, there are different associated syndromes such as liver depression, spleen deficiency, dampness stagnancy, and yin deficiency, due to differences of individual situation. With feature selection, we screen out ten key factors which are essential to syndrome differentiation in TCM. The average precision of multilabel classification model reaches 80%.
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- 2015
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11. [Regulative effects of Chinese herb-compound on blood rheology and circulatory system of rabbits under simulated weightlessness].
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Shi HZ, Li YZ, Shen XY, Fan QC, and Bai GE
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- Animals, Blood Circulation drug effects, Blood Viscosity drug effects, Cholesterol, Erythrocyte Deformability drug effects, Head-Down Tilt, Heart Rate physiology, Hematocrit, Hypotension, Orthostatic prevention & control, Lipoproteins, LDL drug effects, Lower Body Negative Pressure, Rabbits, Tilt-Table Test, Triglycerides, Cardiovascular Physiological Phenomena drug effects, Drugs, Chinese Herbal pharmacology, Rheology drug effects, Weightlessness Countermeasures, Weightlessness Simulation adverse effects
- Abstract
Objective: To investigate effects of Chinese herb-compound on blood rheology and circulatory system of rabbits under simulated weightlessness in order to provide bases for protecting against the influence of simulated weightlessness on cardiovascular function., Method: Rabbits were exposed to head-down tilt (HDT -20 degrees) for 9 d to simulate weightlessness. The effect of Chinese herb-compound on indices related to blood rheology, blood-fat and orthostatic tolerance in these rabbits were examined., Result: After head-down tilt, hematocrit value and red blood cells deformability decreased significantly; cholesterol and low density lipoprotein increased markedly; plasma fibrinogen content and triglyceride showed increasing trend. Administration of the Chinese herb-compound didn't improve the blood rheology indices, but showed a trend to decrease triglyceride and to inhibit the increase of cholesterol. In the head-up tilt (HUT) plus lower body negative pressure (LBNP) experiment, orthostatic tolerance time of the rabbits in the control group decreased, and myocardial ischemic changes in ECG, such as dropped ST segment, inverse T wave, and arrhythmia were observed. While in the Chinese herb-compound group, the heart rate of the rabbits kept smooth, ischemic changes in ECG were not clear, and orthostatic tolerance time increased., Conclusion: The Chinese herb-compound shows an effect of preventing orthostatic tolerance from decreasing, and improves blood-fat metabolism. It regulates different human systems on the whole, and increases ability of adaptation to ill environment.
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- 2005
12. Effects of L.F04, the active fraction of Lycopus lucidus, on erythrocytes rheological property.
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Shi HZ, Gao NN, Li YZ, Yu JG, Fan QC, Bai GE, and Xin BM
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- Animals, Blood Viscosity drug effects, Dextrans pharmacology, Hemorheology, Male, Rats, Rats, Wistar, Space Flight, Drugs, Chinese Herbal administration & dosage, Erythrocyte Aggregation drug effects, Erythrocyte Deformability drug effects, Hemostasis drug effects, Lycopus
- Abstract
Objective: To study the effects of L.F04, the active fraction of Lycopus lucidus, on erythrocytes rheological property so as to investigate its mechanism in promoting blood circulation and removing blood stasis., Method: The effects of L.F04 (used for treatment for 10 days in different dosages) on deformability, aggregation and membrane liquidity of erythrocytes (MLE) as well as whole blood apparent viscosity (eta(b)) were examined on the basis of rat model of blood-stasis syndrome induced by venous injection of high molecular weight dextran., Result: As compared with the normal control group, the model group's RBC deformability and MLE were lower, and the aggregation of erythrocytes and eta(b) were higher. Compared with the model group, both L.F04 0.612 g/kg and 0.306 g/kg showed significant effect in improving deformability and inhibiting aggregation of red blood cells (RBC) and reducing blood viscosity. The trend of improving MLE was also shown., Conclusion: L.F04 could significantly improve the abnormal rheological property of erythrocytes.
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- 2005
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13. [Effects of Chinese herb compound on myocardial SDH, ATP-ase and energy reserves in tail-suspended rats].
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Wang BZ, Li YZ, Xin BM, Fan QC, and Bai GE
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- Adenosine Triphosphatases metabolism, Animals, Energy Metabolism drug effects, Heart drug effects, Hindlimb Suspension, Male, Myocardium metabolism, Rats, Rats, Sprague-Dawley, Succinate Dehydrogenase metabolism, Adenosine Triphosphatases drug effects, Drugs, Chinese Herbal pharmacology, Myocardium enzymology, Succinate Dehydrogenase drug effects, Weightlessness Simulation
- Abstract
Objective: To investigate effects of Chinese herb compound on myocardial SDH, ATP-ase and energy reserves in tail-suspended rats., Method: Male SD rats were randomly divided into three groups (n=10 each): (A) normal control group; (B) tail-suspended group; (C) tail-suspended + Chinese Medical herb compound group. Rats in group B and C were tail-suspended (-30 degrees) for 5 d to simulate weightlessness. All rats B were decapitated after the experiment. Myocardial SDH (method of Anderson N-BT), ATP-ase (method of Wachstein and Meisel) and energy reserves (method of HPLC) were examined., Result: Compared with rats in groups A and C, SDH activity increased, SDH staining deepened, value of OD SDH enhanced, ATP-ase activity and OD value increased and enhanced significantly (P<0.01) but value of myocardial energy reserves decreased in group B rats., Conclusion: Tail-suspension strengthens compensatory oxidation metabolism of cardiac muscle and activates SDH and ATP-ase, at the same time decrease, myocardial energy reserves. Normal are maintained the low level of metabolism by the medical herb compound used which shows a protecting effects through mitigation, tranguilization and replenishment of Qi.
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- 2004
14. Effects of active fractions from Lycopus lucidus L. F04 on platelet aggregation and thrombus formation.
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Shi HZ, Gao NN, Li YZ, Yu JG, Fan QC, and Bai GE
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- Animals, Anticoagulants pharmacology, Dextrans pharmacology, Dose-Response Relationship, Drug, Drugs, Chinese Herbal therapeutic use, Male, Rats, Rats, Wistar, Thrombosis drug therapy, Blood Coagulation drug effects, Drugs, Chinese Herbal pharmacology, Lycopus, Phytotherapy, Platelet Aggregation drug effects
- Abstract
Objective: To study the effect of active fractions from Lycopus lucidus (L. F04) on platelet aggregation and thrombus formation so as to investigate its mechanism of promoting blood circulation and removing blood stasis., Method: The effects of Lycopus lucidus L. F04 on platelet aggregation induced by ADP in vivo, and thrombosis of artery-vein by-pass and thrombus formed in circuitous loop in vitro were examined using the blood stasis animal model of rats made by injecting high molecular weight dextran (HMWD)., Result: The increase of maximum platelet aggregation rate induced by ADP in vivo in HMWD model was evidently inhibited with 0.408 g/kg or 0.204 g/kg or L. F04, and the effect showed a trend of concentration-dependence. As compared with the control, the thrombus weight in rat model of blood stasis increased clearly and its length showed only a trend of increase. Both 0.408 g/kg and 0.204 g/kg of L. F04 had the effect of resisting the thrombus formation, while 0.408 g/kg showed better effects of reducing the thrombus dry weight and wet weight. Both 0.408 g/kg and 0.204 g/kg of L. F04 could inhibit the thrombosis in artery-vein by-pass; the inhibition rates were 27.41% and 27.14% respectively., Conclusion: Lycopus lucidus L. F04 could significantly inhibit platelet aggregation and thrombus formation.
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- 2004
15. [Effects of Qiang Gu Kang Wei prescription on morphology of bone in rats under simulated weightlessness].
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Li YZ, Shi HZ, Fan QC, Tao Y, Bai GE, Duan YR, and Xie JS
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- Animals, Dose-Response Relationship, Drug, Hindlimb Suspension, Microscopy, Electron, Osteoblasts drug effects, Osteoclasts drug effects, Periosteum drug effects, Rats, Tibia cytology, Drugs, Chinese Herbal pharmacology, Epiphyses drug effects, Tibia drug effects, Tibia ultrastructure, Weightlessness Simulation
- Abstract
Objective: To investigate effects of Qiang Gu Kang Wei prescription on bone morphology in tail-suspended rats., Method: Rats were tail-suspended (-30 degrees) for 21 d to simulate weightlessness. The effects of this prescription on thickness of periost and cortex at epiphyseal plate of tibial shaft and 3 mm under it were examined. The effects of this prescription on histology and ultrastructure of tibia were also observed., Result: Compared with the normal control, cortex at both epiphyseal plate of tibial shaft and 3 mm under it in suspended rats thinned significantly (P<0.01 or P<0.05). Histological observation showed that in bone of suspended rats, uncalcific matrix was more, bone cells' number was lower and their appearance was more infantile, osteoblasts were less and smaller, while osteoclasts were more and larger, haversian system of transection also showed more irregular than in bone of normal control. Ultrastructure observation showed that the function of osteoblasts was inhabited and that of osteoclasts was active. All the three doses groups of the prescription could increase cortex at either epiphyseal plate of tibial shaft or 3 mm under it (P<0.01 or P<0.05) compared with the tail-suspended group. The appearance of bone in the three groups was improved as well under optical or electron microscope., Conclusion: This prescription could improve abnormal change in bone morphology resulted from being tail-suspended in rats and make it normal.
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- 2003
16. [Preliminary (correction of Priliminary) study on effects of "planning treatment according to diagnosis" on physiological changes during simulated weightlessness].
- Author
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Wang BZ, Li YZ, Xin BM, Fan QC, Wang J, and Xue CM
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- Adolescent, Adult, Blood Viscosity physiology, Cortisone blood, Cortisone metabolism, Erythrocyte Deformability physiology, Head-Down Tilt, Humans, Kidney drug effects, Spleen drug effects, Urine, Xylose metabolism, Xylose urine, Bed Rest, Blood Viscosity drug effects, Drugs, Chinese Herbal therapeutic use, Erythrocyte Deformability drug effects, Weightlessness Simulation
- Abstract
Objective: To observe effects of the planning treatment according to diagnosis on body syndromes caused by simulated weightlessness., Method: Ten subjects underwent HDT -6 degrees for 14 d were randomly divided into the traditional Chinese Medicine group (ME) and control group (CON). Differentiation of syndromes were made and parameters related to the differentiation syndromes, including plasma cortisone, blood viscosity, red cell deformation, excretion rate of urine xylose, and amount of urine were surveyed simultaneously., Result: Both differentiation of syndromes and the physiological parameters in group ME could be maintained at the pre-bed rest levels or changed only slightly., Conclusion: The Chinese herb compound had an adjusting effect on deficiency of kidney-Yin, blood stasis, insufficiency of spleen-Qi and changes of related physiological parameters caused by 14 d bed rest simulated weightlessness, among which the effect on deficiency of kidney-yin and blood stasis were more distinct.
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- 2003
17. [Effects of "Qiang Gu Kang Wei" compound prescription on biochemical indices of bone and related organs in rats under simulated weightlessness].
- Author
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Li YZ, Shi HZ, Fan QC, Bai GE, Duan YR, and Xie JS
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- Alkaline Phosphatase blood, Alkaline Phosphatase metabolism, Animals, Calcium blood, Calcium metabolism, Dose-Response Relationship, Drug, Hindlimb Suspension adverse effects, Hydroxyproline blood, Hydroxyproline metabolism, Osteocalcin blood, Osteocalcin metabolism, Phosphorus blood, Phosphorus metabolism, Rats, Bone and Bones drug effects, Bone and Bones metabolism, Drugs, Chinese Herbal pharmacology, Intestine, Small drug effects, Intestine, Small metabolism, Weightlessness Simulation adverse effects
- Abstract
Objective: To investigate effects of "Qiang Gu Kang Wei" prescription on biochemical indices of bone and related organs in tail-suspended rats., Method: Rats were tail-suspended (-30 degrees) for 21 d to simulate weightlessness. The effect of this prescription on biochemical indices such as Ca, P in serum, osteocalcin (BGP) in serum and bone, oxyproline hydroxyproline (Hyp) in bone, alkaliphosphatase (ALP) in serum, small intestine and bone in these rats were examined., Result: Comparing with the normal control, serum Ca decreased significantly (P<0.05) while serum P showed only a trend to decrease, at the same time BGP dropped in both serum and bone (P<0.05) and Hyp dropped only in bone (P<0.05). There was significant decrease of ALP activity in serum, small intestine and bone (P<0.01 or P<0.05) in suspended rats. The prescription showed different effects with different doses. In all the three dose groups (30 g/kg, 20 g/kg, 10 g/kg) Ca and P in serum levels increased (P<0.01 or P<0.05), BGP in serum and bone improved (P<0.05) or showed only a trend to increase. ALP activity increased in serum, small intestine and bone (P<0.05). Increase of Hyp in bone was found in the middle and the small dose groups (P<0.05)., Conclusion: This prescription shows an effect of improving biochemical indices in bone and related organs such as serum and small intestine in tail-suspended rats. But no distinct concentration-dependence was found.
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- 2003
18. [Effects of "Qiang Gu Kang Wei" compound prescription on bone metabolism in rats under simulated weightlessness].
- Author
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Fan QC, Li YZ, Bai GE, Duan YR, Xie JS, and Shi HZ
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- Animals, Biomechanical Phenomena, Dose-Response Relationship, Drug, Femur drug effects, Femur metabolism, Male, Osteocalcin blood, Osteocalcin drug effects, Osteocalcin metabolism, Rats, Rats, Sprague-Dawley, Bone Density drug effects, Bone and Bones drug effects, Bone and Bones metabolism, Drugs, Chinese Herbal pharmacology, Weightlessness Simulation
- Abstract
Objective: To investigate the effect of "Qiang Gu Kang Wei" prescription on bone metabolism in simulated weightless rats., Method: Male SD rats were randomly divided into five groups: 1) free active control (FAC); 2) tail-suspended control (TS); 3) tail-suspended and treated with large dose of the prescription (TS + L) (30 g/kg); 4) tail-suspended and treated with middle dose of the prescription (TS + M) (20 g/kg); 5) tail suspended and treated with small dose of the prescription (TS + S) (10 g/kg). The experiment lasted 3 weeks. The effect of the prescription on bone biomechanical properties, bone density, bone mineral contents, and bone biochemical markers of bone metabolism were examined., Result: Bone biomechanical properties, bone density, total and bound bone gla protein (BGP) of serum all increased significantly in three groups treated with the prescription., Conclusion: "Qiang Gu Kang Wei" prescription prevents bone loss, hence maintains bone density and bone biomechanical properties under simulated weightlessness.
- Published
- 2003
19. [Effects of active fractions from Lycopus lucidus L. F04 on erythrocyte rheology [correction of erythrocyterheology]].
- Author
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Shi HZ, Gao NN, Li YZ, Yu JG, Fan QC, and Bai GE
- Subjects
- Animals, Blood Viscosity drug effects, Erythrocyte Aggregation drug effects, Erythrocyte Deformability drug effects, Hemostasis drug effects, Rats, Rats, Wistar, Anticoagulants pharmacology, Dextrans pharmacology, Drugs, Chinese Herbal pharmacology, Hemorheology drug effects, Lycopus
- Abstract
Objective. To study the effects of active fractions from Lycopus lucidus (L. F04) on erythrocyte rheology so as to investigate its mechanism of promoting blood circulation and removing blood stasis. Method. The effects of L. F04 on erythrocytes deformability, aggregation, liquidity of membrane were examined in the present study and the blood stasis animal model of rats made by injecting high molecular weight dextran (HMWD) was used. Result. HMWD injection decreased red blood cells deformability (P<0.05) and liquidity of membrane (P<0.01) and increased erythrocytes aggregation (P<005). Compared with the model, both L. F04 0.612 g/kg and 0.306 g/kg improved red blood cells deformability (P<0.05), inhibited erythrocytes aggregation (P<0.05), and showed the trend of improving liquidity of membrane. But there was no concentration-dependence. Conclusion. L. F04 can significantly improve the deviant erythrocyte rheology characteristics.
- Published
- 2002
20. [Effects of Qiang Gu Kang Wei compound on hemorheology in tail-suspended rats].
- Author
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Li YZ, Shi HZ, Fan QC, Bai GE, Duan YR, and Xie JS
- Subjects
- Animals, Blood Sedimentation drug effects, Dose-Response Relationship, Drug, Erythrocyte Aggregation drug effects, Erythrocyte Deformability drug effects, Fibrinogen drug effects, Hematocrit, Hindlimb Suspension, Rats, Rats, Sprague-Dawley, Blood Viscosity drug effects, Drugs, Chinese Herbal pharmacology, Hemorheology drug effects, Weightlessness Simulation adverse effects
- Abstract
Objective. To investigate the effects of Qiang Gu Kang Wei compound on hemorheology in tail-suspended rats. Method. Rats were tail-suspended (-30 degrees) for 21 d to simulate weightlessness. The effect of the compound on erythrocyte sedimentation rate (ESR), hematocrit value (HCT), plasma fibrinogen content (PFC), blood viscosity, red blood cells deformability and erythrocytes aggregation were examined. Result. PFC, whole blood reducing viscosity (eta h), whole blood viscosity (eta b), erythrocyte rigid index (IR) and maximum aggregation index (MAXD) increased significantly (P<0.01 or P<0.05 ) and maximum deformity index (DImax) (P<0.01) decreased significantly in suspended rats as compared with the normal control. Different doses of the compound showed different effects. The small dose group (10 g/kg) inhabited eta h and eta b (P<0.01 or P<0.05) of all shear rates, abnormal IR and MAXD (P<0.01); The middle dose group (20 g/kg) decreased PFC (P<0.01); The big dose group (30 g/kg) inhabited eta h and eta b (P<0.01 or P<0.05) of high shear rates, decreased IR (P<0.01), and improved DImax (P<0.01). Conclusion. This compound could improve hemorheology in tail-suspended rats. But there was no concentration-dependence.
- Published
- 2002
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