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Your search keyword '"Fan, Hui-Ran"' showing total 7 results
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7 results on '"Fan, Hui-Ran"'

1. Input associativity underlies fear memory renewal

Author

Li, Wei-Guang, primary, Wu, Yan-Jiao, additional, Gu, Xue, additional, Fan, Hui-Ran, additional, Wang, Qi, additional, Zhu, Jia-Jie, additional, Yi, Xin, additional, Wang, Qin, additional, Jiang, Qin, additional, Li, Ying, additional, Yuan, Ti-Fei, additional, Xu, Han, additional, Lu, Jiangteng, additional, Xu, Nan-Jie, additional, Zhu, Michael Xi, additional, and Xu, Tian-Le, additional

Published
2021
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5. Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity

Author

Fan, Hui-Ran, primary, Du, Wei-Feng, additional, Zhu, Tao, additional, Wu, Yan-Jiao, additional, Liu, Yan-Mei, additional, Wang, Qi, additional, Wang, Qin, additional, Gu, Xue, additional, Shan, Xingyue, additional, Deng, Shining, additional, Zhu, Tailin, additional, Xu, Tian-Le, additional, Ge, Wei-Hong, additional, Li, Wei-Guang, additional, and Li, Fei, additional

Published
2018
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7. Methyleugenol Potentiates Central Amygdala GABAergic Inhibition and Reduces Anxiety.

Author

Liu YM, Fan HR, Deng S, Zhu T, Yan Y, Ge WH, Li WG, and Li F

Subjects
Anesthetics pharmacology, Anesthetics therapeutic use, Animals, Central Amygdaloid Nucleus drug effects, Eugenol pharmacology, Eugenol therapeutic use, GABAergic Neurons drug effects, HEK293 Cells, Humans, Male, Mice, Mice, Inbred C57BL, Neural Inhibition physiology, Organ Culture Techniques, Anxiety drug therapy, Anxiety metabolism, Central Amygdaloid Nucleus metabolism, Eugenol analogs & derivatives, GABAergic Neurons metabolism, Neural Inhibition drug effects
Abstract

The central amygdala (CeA) plays a critical role in the expression of emotional behaviors, including pathologic anxiety disorders. The present study demonstrated that GABAergic inhibition in CeA was significantly increased by methyleugenol (ME), a natural constituent isolated from the essential oils of several plants. The electrophysiologic recordings showed that ME increased both tonic and miniature inhibitory postsynaptic GABAergic currents in CeA slices, especially the tonic currents, while the miniature excitatory postsynaptic currents were not affected. In the fear-induced anxiety animal model, both intraperitoneal injection or CeA-specific infusion of ME reduced the anxiety-like behaviors in mice, likely by facilitating the activation of A-type GABA receptors (GABA A Rs). These results reveal that GABA A R in the CeA can be a potential therapeutic target for the treatment of anxiety and that ME is capable of enhancing the GABAergic inhibition in CeA neurons for the inhibition of neuronal excitability., (Copyright © 2018 by The American Society for Pharmacology and Experimental Therapeutics.)

Published
2019
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