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The use of quantile regression in analyzing determinants of life expectancy provides a deep understanding of the influence of predictor variables across various quantiles of the data distribution. The analysis results reveal significant differences in predictor variables affecting life expectancy at each quantile, with socio-economic, environmental, and health program factors having varying impacts. Model evaluation is conducted considering several goodness-of-fit measures such as MAPE, AIC, and coefficient of determination, selecting the best quantile based on a combination of these values. Based on the analysis, the optimal quantile is chosen based on the lowest MAPE and AIC, and the highest coefficient of determination, considering the efficiency of significant predictor variables. The analysis indicates that the best model is found at the 60th quantile, with two significant predictor variables, namely mean years of schooling and labor force participation. This underscores the significant role of socio-economic factors in determining life expectancy at specific quantiles

The creative economy is a new era of economic concepts that prioritizes information and creativity and relies on human resources' ideas as the primary production factor in economic activities. Pariaman City's traditional embroidered cloth business is one of the creative industries of the fashion sub-sector. The Embroidery Naras fabric business in Kota Pariaman has seen a drastic decrease in sales turnover since the Covid-19 pandemic, so entrepreneurs are looking for alternative solutions to increase their sales again. This research aims to find solutions to the problems faced by embroidered fabric craftsmanship, specifically how to increase sales volume after the covid-19 pandemic by advancing the creative embroidered fashion industry through the role of increasing production, creativity, and innovation. There are two types of data used: primary data and secondary data. Data collection, data reduction, data presentation, and conclusions are the data analysis techniques used in this study. According to the findings, increasing production played only a 33% role. This demonstrates that craftsmen play a smaller role in increasing production to 100%. While the criteria for increasing creativity reaches 70%, it demonstrates that it plays an important role in increasing sales volume. It reaches 15% for the global marketing criteria, indicating that it does not play a role in global marketing, and it reaches only 3% for the use of technology, indicating that it does not play a role in the production process. Similarly, increasing revenue by 33%, As a result, it plays a smaller role in increasing revenue through direct and online sales.

Changes and developments in the national, regional, and global environment have triggered the rapid development of transnational crime, in this context, the Indonesian National Police (Polri) with the authority to act as state apparatus and law enforcer is the spearhead and front guard of the criminal justice system in eradicating transnational crime. Related to the foregoing, the applicability of International Criminal Law and its application in Indonesia is still an unresolved problem. In connection with the above, in terms of reviewing and analyzing related to the prospects of international criminal law and challenges to the Indonesian National Police, the author use normative juridical research methods using library research. The Juridical-Normative research method is a research method that places legal principles and legal rules as a touchstone to assess whether there was actually a violation or not. So, it can be concluded that there is a need to strengthen and develop international criminal law which is supported by comparative studies and activities in the framework of comparative law or comparative study of international criminal law studies at S1 STIK-PTIK. In the Elucidation of Article 7 of the Human Rights Court Law, it is stated that “the crimes of genocide and crimes against humans in this provision are in accordance with the Rome Statute of the International Criminal Court (Article 6 and Article 7)”. This provision raises the consequence that the legal spirit, interpretation, elements, and application must follow and comply with the provisions contained in the ICC Statute. In the course of the following, several serious human rights violations have been examined and tried based on the Human Rights Court Law with the establishment of an Ad Hoc Human Rights Court, such as the East Timor Post-Ballot case and the Abepura case.

Penelitian ini bertujuan untuk mengetahui usaha tokoh masyarakat dalam mendorong pemanfaatan rumah ibadah di Jorong Tabek Sumatera Barat. Rumah ibadah masih difungsikan sebagai tempat dilaksanakan shalat wajib dan belum terdapat kegiatan keagamaan ataupun kegiatan sosial lainnya. Metode yang digunakan dalam penelitian ini adalah metode penelitian deskriptif kualitatif yang menghasilkan data berupa kata-kata tertulis atau lisan dari orang-orang atau perilaku yang dapat diamati dengan tujuan menggambarkan keadaan sasaran penelitian menurut apa adanya. Teknik pengumpulan data dalam penelitian ini melalui observasi, wawancara, serta dokumentasi dalam bentuk gambar dan rekaman suara. Usaha-usaha yang dilakukan oleh Tokoh Masyarakat adalah melakukan koordinasi dan sosialisasi yang baik dan efektif terhadap masyarakat untuk melibatkan diri menyemarakkan masjid sebagai pusat sarana peribadatan dan sarana kegiatan keummatan. Usaha yang dilakukan oleh tokoh masyarakat salah satunya memprogramkan kegiatan tertentu untuk diikuti oleh masyarakat yang bertujuan untuk mengembangkan dan menambah ilmu. Dalam program kegiatan tersebut tokoh masyarakat ikut serta memfasilitasi masyarakat sebagai aktor penggerak, pendukung, dan pelaksana, sehingga terjalin pendekatan emosional spriritual yang baik antara tokoh masyarakat dengan masyarakat.

One of the renewable energy source that is abundant but has not been used optimally is wind energy. Roads are currently the main transportation infrastructure along with the increasing number of motorized vehicles. Wind is one of the best renewable energy sources that can be utilized on the highway where it can be used as a power source to drive the Vertical Axis Wind Turbine (VAWT). Darrieus type turbines can operate at low wind speeds and do not require a specific wind direction. However, the installation of this wind turbine on the highway can be hampered due to the presence of highway light poles. We simulate a light pole as a blunt object placed in front of the turbine which will then be observed for the ratio of torque produced to compare the performance of the turbine with a blunt body and without a blunt body. This study aims to determine the effect of the diameter ratio and distance between the turbine and the blunt object on the torque generated on the rotor. This research uses CFD simulation on NACA 4415 foil. The results showed that placing a blunt object in front of the Darrieus turbine increased the turbine torque. The most optimal increase in torque is obtained at a distance of 700 mm with a blunt body diameter of 0.6 DT or 0.3 DT which can increase the torque output of the turbine.

Kondisi stress oksidatif dapat mempengaruhi makromolekul seluler dan ekstraseluler (protein, lipid, asam nukleat dan DNA) sehingga dapat mengalami kerusakan oksidatif pada jaringan tubuh yang memicu terjadinya penyakit degeneratif melalui beberapa jalur oksidasi didalam tubuh. Penelitian ini bertujuan untuk menentukan aktivitas antioksidan dari ekstrak buah kersen dengan metode TAC dan CUPRAC. Sampel segar buah kersen dikumpulkan kemudian dilakukan proses pembuatan simplisia yang kemudian dilakukan proses ekstraksi dengan menggunakan metode maserasi untuk dilakukan proses penyarian dengan pelarut etanol 70% hingga diperoleh ekstrak kental buah kersen (EE). Ekstrak kental buah kersen kemudian dilakukan proses pemisahan dengan metode ekstraksi cair-cair menggunakan pelarut n-heksan, etil asetat dan etanol-air (1:9) sehingga diperoleh fraksi n-heksan (HF), fraksi etil asetat (EAF) dan fraksi etanol-air (EF). Kemudian masing-masing sampel di uji aktivitas antioksidan dengan menggunakan metode Total Antioxidant Capacity (TAC) dan Cupric ion Power Reducing Antioxidant Capacity (CUPRAC). Hasil yang diperoleh yaitu pada metode TAC, EAF memiliki aktivitas yang lebih baik dengan nilai Quercetin Equivalen Antioxidant Capacity (QEAC) 57,1±1,03 µM/mg dibandingkan dengan EE, EF dan HF. Sedangkan pada metode CUPRAC diperoleh hasil bahwa EAF memiliki aktivitas antioksidan dalam mereduksi Cu yang lebih baik dengan nilai Gallic Acid Equivalen Antioxidant Capacity (GAEAC) 13,13±0,008 µM/mg dibandingkan dengan EE, EF dan HF. Hal ini menunjukkan bahwa buah kersen memiliki potensi aktivitas antioksidan yang baik. Fraksi etil asetat (EAF) dari buah kersen memiliki potensi sebagai antioksidan dalam mereduksi Mo dan ion Cu dengan menggunakan metode TAC dan CUPRAC. Adanya data ilmiah dari penelitian ini dapat memberikan kontribusi dalam pengembangan buah kersen sebagai food suplement antioksidan yang berguna untuk kesehatan masyarakat.

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The black mulberry plant has been widely developed for its bioactivity as natural medicine. This study evaluated plant extracts' total phenolic and flavonoid content and their correlation to black mulberry stem's antioxidant activity and toxicity. Dry powder from the black mulberry stem was extracted by maceration with 96% ethanol to obtain a thick extract (TE) and fractionated using hexane (HF), ethyl acetate (EAF), and Ethanol-aqueous (EF). The samples were analyzed for a compound using reagents and the determination of total phenolic and flavonoid content. The samples were evaluated for antioxidant activity using several parameters and their cytotoxic effects using the BSLT method. Identification of compounds in EAF was confirmed to contain phenolic, flavonoids, alkaloids, saponins, tannins, steroids, and terpenoids. EAF showed higher phenolic and flavonoid content than others. The evaluation of antioxidant activity showed that extracts and fractions from mulberry stems showed the ability to reduce ions and free radicals. EF sample has activity in reducing Mo (IV) ion by TAC method of 98.82±0.53 µM/mg, indicating substantial antioxidant capacity. In addition, EAF samples showed potential activity in reducing DPPH, hydroxyl, and peroxide radicals in the BCB method with IC50 values of 12.13 µg/mL, 42.06 µg/mL, and 57.6 µg/mL, respectively. Similar activity was also seen in the cytotoxic effect of a robust EAF sample with an LC50 value of 16.31 µg/mL. From the results obtained, EAF can be developed as a raw material for traditional medicine as an antioxidant and anticancer candidate with a significant content of flavonoids and phenolics.

This study aims to examine the economic empowerment model applied by the Minangkabau community, which is known as a society that holds firmly to values, traditions, culture and religion, besides that Minangkabau people have long been known as Minang merchants who adhere to a communal economic system. The cooperative economic system implemented by the Minangkabau community is able to maintain the economic stability of the Minangkabau community, it is necessary to conduct a study to see the model of economic empowerment of the Minangkabau community. The research method used is library research by collecting data through reference books, published scientific journals and other literature to see the applied economic empowerment model. The data collection method is carried out by collecting study materials, reading, making research notes and reviewing study materials related to the research focus. The findings of this study are that the Minangkabau community's economy is stable and able to withstand economic shocks by applying several models of economic empowerment, namely mutual cooperation, cooperation, wandering and trading. Keywords: Empowerment, Minangkabau, Economic Aspect

Cancer is a condition of abnormal cell proliferation of tissue cells in the body that becomes malignant. It can attack other parts of the body and affect the normal function of the body organs. The sample used in this study was red nails or tubers, then extracted using 96% ethanol eluent to obtain a thick extract. The ethanolic extract of the red ferns was fractionated using column chromatography to obtain the active fraction to characterize the compound using Thin Layer Chromatography and Gas Chromatography-Mass Spectroscopy (GC-MS) and tested its cytotoxic effectiveness on MCF-7 cancer cells and HeLa cancer cells. The results of this study were obtained from fractionation using the column chromatography method to obtain sub-fraction C and the results of compound characterization using GC-MS and obtained variations in the class of compounds contained in the sample, namely amino acids, glucosinolates, alkaloids, flavonoids, and terpenoids. Based on the cytotoxic effect test of sub-fraction C on MCF-7 cancer cells, the results obtained moderate cytotoxic effects with an IC50 value of 61.027 µg/mL, and HeLa cancer cells had an IC50 value of 521.03 µg/mL, which was categorized as having a weak cytotoxic effect. Based on the results obtained from this study, it can be concluded that sub-fraction C of A. ferox Copel Tubers has a cytotoxic effect on MCF-7 breast cancer cells to be used as a reference for tracing pure compounds from A. ferox Copel tuber.

Housing and its policy become an interesting issue for the study of social development programs. The CSR program in the housing sector is a form of company involvement in fulfilling access to housing needs as a social responsibility for the impact of company activities on the surrounding community. The method used in this paper is the method of literature or library research, namely by collecting reading material from books, as well as research journals on CSR programs in the housing sector, then analyzing with a qualitative approach so as to produce conclusions as a closing paper. The conclusions in this paper describe the CSR program in the housing sector of PT. Aneka Tambang was carried out in the Nanggung, sub-district of Bogor district. CSR activities are carried out through the home improvement competition program and the implementation of a healthy home improvement. CSR program in the housing sector by PT. Aneka Tambang is a form of company involvement in improving people's welfare as a joint commitment between the government, the private sector and the community.

One of the types of coffee cultivated in Solok Regency is Arabica Coffee (Coffea Arabica L). The quality of the coffee produced can be influenced by the proper harvesting and post-harvest process so as to produce ground coffee with good quality. This research is done by the method of observation, descriptive, and hedonic test. Ground coffee produced in Solok Regency has a semi-mechanical harvesting process while the post-harvest process begins with the release of the skin and meat of the fruit, subsequent drying, and release of the skin of horns, sorting and grading, roasted, milling and packaging. This research aims to study the processing and quality of Arabica Ground Coffee in Solok Regency.

During the first year of the COVID-19 pandemic, healthcare facilities worldwide struggled to adequately care for the increasing number of COVID-19 patients while maintaining quality of care for all other patients. The aim of this study was to investigate the displacement and underuse of non-COVID-19 patient care in a medical department of a tertiary hospital in Switzerland. In this retrospective cross-sectional study, internal medicine admissions from 2017 to 2020, emergency outpatient visits from 2019 to 2020 and COVID-19 admissions in 2020 were analyzed and compared using a regression model. Internal medicine admissions were also stratified by diagnosis. A questionnaire was used to assess the pandemic experience of local general practitioners, referring hospitals, and nursing homes. The total number of admissions decreased during the 1st and 2nd waves of the pandemic but increased between the two waves. Elective admissions decreased in 2020 compared to pre-pandemic years: they represented 25% of total admissions in 2020 versus 30% of the total admissions during 2017-2019, p