1. Rapid isothermal point-of-care test for screening of SARS-CoV-2 (COVID-19)
- Author
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Jean-Marc Zingg, Yu-Ping Yang, Spencer Seely, Pratibha Joshi, Md Harun Or Roshid, Fabiola Iribarren Latasa, Gregory O'Connor, Jennifer Alfaro, Eduardo Riquelme, Sebastian Bernales, Emre Dikici, Sapna Deo, and Sylvia Daunert
- Subjects
Coronavirus ,Point of care (PoC) test ,Lateral flow assay (LFA) ,Recombinase polymerase amplification (RPA) ,Isothermal amplification ,Reverse transcription recombinase polymerase amplification (RT-RPA) ,Medicine - Abstract
Rapid on-site diagnosis of emerging pathogens is key for early identification of infected individuals and for prevention of further spreading in a population. Currently available molecular diagnostic tests are instrument-based whereas rapid antibody and antigen tests are often not sufficiently sensitive for detection in pre-symptomatic subjects. There is a need for rapid point of care molecular screening tests that can be easily adapted to emerging pathogens and are selective, sensitive, reliable in different settings around the world. We have developed a simple, rapid (
- Published
- 2023
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