794 results on '"Fabbro D"'
Search Results
2. ASO Visual Abstract: The Histopathological Growth Pattern of Colorectal Liver Metastases Impacts Local Recurrence Risk and the Adequate Width of the Surgical Margin
- Author
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Viganò, L., Branciforte, B., Laurenti, V., Costa, G., Procopio, F., Cimino, M., Del Fabbro, D., Di Tommaso, L., and Torzilli, G.
- Published
- 2022
- Full Text
- View/download PDF
3. Cancer Biology and the Principles of Targeted Cancer Drug Discovery
- Author
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Hillmann, P., primary, Schmitz, D., additional, Mestan, J., additional, D’Alonzo, S., additional, and Fabbro, D., additional
- Published
- 2017
- Full Text
- View/download PDF
4. Targeted Therapy with Imatinib: An Exception or a Rule?
- Author
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Fabbro, D., Fendrich, G., Guez, V., Meyer, T., Furet, P., Mestan, J., Griffin, J. D., Manley, P. W., Cowan-Jacob, S. W., Starke, K., editor, Born, G.V.R., editor, Eichelbaum, M., editor, Ganten, D., editor, Hofmann, F., editor, Kobilka, B., editor, Rosenthal, W., editor, Rubanyi, G., editor, Pinna, Lorenzo A., editor, and Cohen, Patricia T.W., editor
- Published
- 2005
- Full Text
- View/download PDF
5. Antisense Oligonucleotides and Their Anticancer Activities
- Author
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Fabbro, D., Müller, M., Geiger, T., and Crooke, Stanley T., editor
- Published
- 1998
- Full Text
- View/download PDF
6. Caractéristiques et parcours de soins des patients admis au service d’accueil des urgences du centre hospitalier universitaire de Strasbourg pour exacerbation d’asthme en 2018
- Author
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Fabbro, D., primary, Khayath, N., additional, De Blay, F., additional, and Fabacher, T., additional
- Published
- 2022
- Full Text
- View/download PDF
7. The concise guide to pharmacology 2021/2: enzymes
- Author
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Alexander, S.P., Fabbro, D., Kelly, E., Mathie, A., Peters, J.A., Veale, E.L., Armstrong, J.F., Faccenda, E., Harding, S.D., Pawson, A.J., Southan, C., Davies, J.A., Boison, D., Burns, K.E., Dessauer, C., Gertsch, J., Helsby, N.A., Izzo, A.A., Koesling, D., Ostrom, R., Pyne, N.J., Pyne, S., Russwurm, M., Seifert, R., Stasch, J.P., Stelt, M. van der, Vliet, A. van der, Watts, V., and Wong, S.S.
- Abstract
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15542. Enzymes are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
- Published
- 2021
8. Prostate cancer diagnosis through electronic nose in the urine headspace setting: a pilot study
- Author
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Asimakopoulos, A D, Del Fabbro, D, Miano, R, Santonico, M, Capuano, R, Pennazza, G, D'Amico, A, and Finazzi-Agrò, E
- Published
- 2014
- Full Text
- View/download PDF
9. Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology
- Author
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Vascotto, C, Lirussi, L, Poletto, M, Tiribelli, M, Damiani, D, Fabbro, D, Damante, G, Demple, B, Colombo, E, and Tell, G
- Published
- 2014
- Full Text
- View/download PDF
10. Analysis of Allele Frequencies of Two Polymorphic Loci in a North-East Italian Population
- Author
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Fattorini, P., Callegaro, A. P., Florian, F., Fabbro, D., Frisan, T., Altamura, B. M., Graziosi, G., Berghaus, G., editor, Brinkmann, B., editor, Rittner, C., editor, and Staak, M., editor
- Published
- 1991
- Full Text
- View/download PDF
11. EGFR expression is linked to osteopontin and Nf-κB signaling in clear cell renal cell carcinoma
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Matušan-Ilijaš, K., Damante, G., Fabbro, D., Đorđević, G., Hadžisejdić, I., Grahovac, M., Avirović, M., Grahovac, B., Jonjić, N., and Lučin, K.
- Published
- 2013
- Full Text
- View/download PDF
12. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors
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Alexander, S.P.H. Fabbro, D. Kelly, E. Mathie, A. Peters, J.A. Veale, E.L. Armstrong, J.F. Faccenda, E. Harding, S.D. Pawson, A.J. Southan, C. Davies, J.A. Beuve, A. Brouckaert, P. Bryant, C. Burnett, J.C. Farndale, R.W. Friebe, A. Garthwaite, J. Hobbs, A.J. Jarvis, G.E. Kuhn, M. MacEwan, D. Monie, T.P. Papapetropoulos, A. Potter, L.R. Schmidt, H.H.H.W. Szabo, C. Waldman, S.A.
- Abstract
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15541. Catalytic receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate. © 2021 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society
- Published
- 2021
13. Trends in kinase drug discovery: targets, indications and inhibitor design
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39.Attwood MM, Fabbro D, Sokolov AV, Knapp S, Schiöth HB
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- 2021
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- View/download PDF
14. Signalübermittlungsinhibitoren: Identifikation und Entwicklung, Tyrosinkinaseinhibitoren, Antiangiogenesefaktoren und Thalidomidanaloga, Proteasomeninhibition
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Weissinger, F., Fabbro, D., and Einsele, H.
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- 2007
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15. The IUPHAR Guide to Immunopharmacology: Connecting Immunology and Pharmacology
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Harding, Simon, Faccenda, Elena, Southan, Christopher, Pawson, Adam, Maffia, P, Alexander, S P H, Davenport, A P, Fabbro, D, Levi-Schaffer, F, Spedding, M, and Davies, Jamie
- Published
- 2020
16. Randomised controlled trial to evaluate a new sealant to prevent biliary fistula in liver surgery: should we reconsider bile leak classification?
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Tagliaferri, V., primary, Cimino, M.M., additional, Procopio, F., additional, Donadon, M., additional, Del Fabbro, D., additional, Palmisano, A., additional, Viganò, L., additional, Galvanin, J., additional, Giudici, S., additional, and Torzilli, G., additional
- Published
- 2021
- Full Text
- View/download PDF
17. Histopathological Growth Pattern of Colorectal Liver Metastases Impacts Local Recurrence Risk and the Adequate Width of Surgical Margin
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Branciforte, B., primary, Viganò, L., additional, Laurenti, V., additional, Costa, G., additional, Procopio, F., additional, Cimino, M., additional, Del Fabbro, D., additional, and Torzilli, G., additional
- Published
- 2021
- Full Text
- View/download PDF
18. Is time to recosinder upfront surgery in case of multiple liver metastases? A weighted comparison in the era of parenchyma-sparing surgery
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Milana, F., primary, Famularo, S., additional, Cimino, M., additional, Corleone, P., additional, Branciforte, B., additional, Franchi, E., additional, Galvanin, J., additional, Procopio, F., additional, Donadon, M., additional, Del Fabbro, D., additional, and Torzilli, G., additional
- Published
- 2021
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- View/download PDF
19. Hepatic and extrahepatic colorectal metastases: discordant pathologic responses to systemic therapy in patients undergoing simultaneous resection of multiple tumor sites
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Corleone, P., primary, Viganò, L., additional, Rimassa, L., additional, Del Fabbro, D., additional, Di Tommaso, L., additional, and Torzilli, G., additional
- Published
- 2021
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- View/download PDF
20. Transversal Hepatectomies. A New Parenchyma-sparing Procedures for Deep-located Hepatic Tumors
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Corleone, P., primary, Procopio, F., additional, Famularo, S., additional, Cimino, M.M., additional, Del Fabbro, D., additional, and Torzilli, G., additional
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- 2021
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- View/download PDF
21. Colorectal Liver Metastases in Contact with Major Intrahepatic Vessels. Does Shrinkage during Chemotherapy Correspond to a Modification of Tumor-vessel Relationship?
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Franchi, E., primary, Vigano', L., additional, Terrone, A., additional, Costa, G., additional, Cimino, M., additional, Procopio, F., additional, Del Fabbro, D., additional, and Torzilli, G., additional
- Published
- 2021
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- View/download PDF
22. Liver resection for primary hepatic neuroendocrine tumours: Report of three cases and review of the literature
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Donadon, M., Torzilli, G., Palmisano, A., Del Fabbro, D., Panizzo, V., Maggioni, M., Santambrogio, R., and Montorsi, M.
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- 2006
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- View/download PDF
23. FACTORS INFLUENCING THE IMPACT OF CONTRAST-ENHANCED INTRAOPERATIVE ULTRASOUND DURING LIVER SURGERY FOR COLORECTAL CANCER LIVER METASTASES: FOS105
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Botea, F., Procopio, F., Correa, V. M., Donadon, M., Cimino, M., Fabbro, D. D., Montorsi, M., and Torzilli, G.
- Published
- 2012
24. Cancer Biology
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Maira, M.-S., primary, Pearson, M.A., additional, Fabbro, D., additional, and García-Echeverría, C., additional
- Published
- 2007
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- View/download PDF
25. Effect of intensive glycaemic control on fibrinogen plasma concentrations in patients with Type II diabetes mellitus. Relation with β-fibrinogen genotype
- Author
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Ceriello, A., Mercuri, F., Fabbro, D., Giacomello, R., Stel, G., Taboga, C., Tonutti, L., Motz, E., and Damante, G.
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- 1998
- Full Text
- View/download PDF
26. Salvage hepatic resection after incomplete interstitial therapy for primary and secondary liver tumours
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Torzilli, G., Del Fabbro, D., Palmisano, A., Marconi, M., Makuuchi, M., and Montorsi, M.
- Published
- 2007
27. Catecholamines vs. metanephrines in the biochemical diagnosis of pheochromocytoma and paraganglioma
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Brenzoni, P., Fabbro, D., Taie, S. Fares, Garcia, S., Gotta, G., Polesel, D. Lotero, Ricci, V., and Kozak, A.
- Subjects
Diagnóstico bioquímico ,Feocromocitoma ,Catecholamines ,Metanephrines ,Biochemical diagnosis ,Metanefrinas ,Pheochromocytoma ,Catecolaminas - Abstract
RESUMEN Los tumores secretores de catecolaminas, feocromocitoma y paraganglioma son entidades poco frecuentes y potencialmente letales si no son diagnosticadas y tratadas a tiempo. El laboratorio cumple un rol fundamental en el diagnóstico y seguimiento de estos tumores a través de la evidencia bioquímica de un exceso de catecolaminas. Sin embargo, muchas veces suele ser dificultoso arribar a un diagnóstico temprano, debido a la baja incidencia de estos tumores y a la dificultad de hallar laboratorios con equipamiento especializado. El marcador bioquímico y las técnicas utilizadas para su medición han ido cambiando con el correr de los años. Tradicionalmente, la medición de catecolaminas en orina era la prueba bioquímica utilizada. Posteriores hallazgos de metabolitos aumentados en la orina de paciente llevaron al uso de ensayos colorimétricos para la detección de ácido vainillin mandélico y metanefrinas como marcadores diagnósticos adicionales de tumor. Las pruebas actuales para el diagnóstico bioquímico muestran una excelente precisión diagnóstica. La medición de metanefrinas libres de plasma utilizando cromatografía líquida de alta resolución con detección electroquímica o de espectrometría de masas en tándem proporciona la máxima precisión para el diagnóstico de estos tumores. ABSTRACT Catecholamine-secreting neuroendocrine tumors called Pheochromocytoma and Paraganglioma are rare entities, but potentially lethal if diagnosis and treatment are not established early enough. Clinical Laboratory plays an important role in the diagnosis and follow-up of these tumors, through the biochemical evidence of a hyperproduction of catecholamines and its metabolites.
- Published
- 2018
28. Ultrasonographically guided surgical approach to liver tumours involving the hepatic veins close to the caval confluence
- Author
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Torzilli, G., Montorsi, M., Del Fabbro, D., Palmisano, A., Donadon, M., and Makuuchi, M.
- Published
- 2006
29. CONTRAST-ENHANCED INTRAOPERATIVE ULTRASONOGRAPHY DURING HEPATECTOMIES for PRIMARY and METASTATIC TUMORS: RESULTS in A PROSPECTIVE COHORT of PATIENTS: 11
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Torzilli, G, Palmisano, A, Del Fabbro, D, Donadon, M, Rottoli, M, and Montorsi, M
- Published
- 2005
30. CONSERVATIVE BUT RADICAL LIVER SURGERY: THE ROLE of INTRAOPERATIVE ULTRASONOGRAPHY: 7
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Torzilli, G, Donadon, M, Del Fabbro, D, Palmisano, A, Panizzo, V, and Montorsi, M
- Published
- 2005
31. Contrast-enhanced ultrasonography during liver surgery
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Torzilli, G., Del Fabbro, D., Olivari, N., Calliada, F., Montorsi, M., and Makuuchi, M.
- Published
- 2004
32. Antisense Oligonucleotides and Their Anticancer Activities
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Fabbro, D., primary, Müller, M., additional, and Geiger, T., additional
- Published
- 1998
- Full Text
- View/download PDF
33. Effect of Intensive Glycemic Control on Fibrinogen Plasma Levels in Diabetic Subjects.
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Mercuri, F., primary, Fabbro, D., additional, Giacomello, R., additional, Stel, G., additional, Taboga, C., additional, Tonutti, L., additional, Damante, G., additional, and Ceriello, A., additional
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- 1998
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- View/download PDF
34. Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro
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Recchia, I., Rucci, N., Festuccia, C., Bologna, M., MacKay, A.R., Migliaccio, S., Longo, M., Šuša, M., Fabbro, D., and Teti, A.
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- 2003
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- View/download PDF
35. Erratum: Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology
- Author
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Vascotto, C, Lirussi, L, Poletto, M, Tiribelli, M, Damiani, D, Fabbro, D, Damante, G, Demple, B, Colombo, E, and Tell, G
- Published
- 2015
- Full Text
- View/download PDF
36. Thyroid-Specific Gene Expression Is Differentially Influenced by Intracellular Glutathione Level in FRTL-5 Cells*
- Author
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Lonigro, R, Donnini, D, Fabbro, D, Perrella, G, Damante, G, Ambesi Impiombato, F S, and Curcio, F
- Published
- 2000
37. Normalização espacial não rígida de imagens assistida por metamodelos
- Author
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Dal Fabbro, D. A. and Thomaz, C. E.
- Subjects
Reconhecimento de padrões ,Normalização espacial de imagens ,Otimização assistida por metamodelos ,Processamento de imagens - Abstract
Classicamente aplicados em simulações computacionais como CFD (Computational Fluid Dynamics) e FEM (Finite Element Method), metamodelos para otimização trouxeram resultados relevantes para aproximar a função objetivo no espaço de busca e resolver problemas em que o cálculo da função objetivo exige elevados recursos computacionais. Recentemente, com a evolução de novos algoritmos de aprendizado de máquina e reconhecimento de padrões, esta técnica também mostrou-se bem sucedida para acelerar o processo de ajuste dos hiperparâmetros de modelos que antes dependiam de um conhecimento profundo sobre os seus fundamentos matemáticos ou da busca exaustiva pelos parâmetros ótimos. Neste contexto, esta dissertação propõe uma metodologia para aplicação de otimização assistida por metamodelos na área de visão computacional, mais especificamente em normalização espacial não rígida de imagens. Este tópico de pesquisa tem sido pouco explorado pela literatura de otimização assistida por metamodelos, além de ser computacionalmente complexo devido às múltiplas opções de ajuste dos parâmetros. Denominada aqui de Normalização Espacial Não Rígida de Imagens Assistida por Metamodelos, a metodologia proposta descreve uma nova métrica que leva em consideração o compromisso em deformar os elementos geométricos da imagem preservando suas características estatísticas principais. Este estudo descreve também duas taxonomias, uma metodologia proposta. Após os experimentos em três bases de imagens distintas, os resultados obtidos mostram que a qualidade da normalização espacial não rígida pode ser otimizada por meio da métrica proposta, e o metamodelo construído auxilia tanto no processo de otimização como na compreensão maior do comportamento da função objetivo no espaço de busca. Classically used for computational simulations such as CFD (Computational Fluid Dynamics) and FEM (Finite Element Method), surrogate-assisted optimization led to consistent findings to approximate the objective function in the search space and to deal with problems where the calculation of the objective function demands excessive computational resources. Recently, along the improvement of new machine learning and pattern recognition algorithms, this technique also proved to be successful in speeding the task of hiperparameter tuning for models which previously relied on a broad understanding about its mathematical principles or brute force search to find the optimal parameters. In this context, this work introduces a framework that applies surrogate-assisted optimization in the field of computer vision, more specifically, in nonrigid image registration. This research topic has been scarcely explored by authors in the literature of surrogate-assisted optimization, besides being computationally intricate due to the multiple options for parameter tuning. Named here as Surrogate-Assisted Nonrigid Registration (SANRR), this proposed framework describes a novel measure that takes into consideration the trade-off between deforming the geometrical elements of the image and retaining its principal statistical features. This study also defines two taxonomies, one regarding optimization and another regarding image registration, prior to establishing the theoretical concepts behind the proposed framework. After the experiments in three different image data sources, the results indicate that the performance and quality of the nonrigid registration can be optimized by the proposed measure, and the trained surrogate model assists with the optimization process, as well as a more extensive comprehension of the behavior of the objective function in the search space.
- Published
- 2018
38. P11.45 Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models
- Author
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von Achenbach, C, primary, Weller, M, additional, Kaulich, K, additional, Gramatzki, D, additional, Zacher, A, additional, Fabbro, D, additional, Reifenberger, G, additional, and Szabó, E, additional
- Published
- 2019
- Full Text
- View/download PDF
39. SUN-LB061 Midnight Salivary Cortisol (MiSC): Diagnostic Concordance in a Normal Sample Population Using Different Immunoassays
- Author
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KOZAK, AE, primary, FENILI, CA, additional, SEQUERA, AM, additional, TORRES, M, additional, RUIBAL, GF, additional, OTERO, P, additional, FARELO, H, additional, GURFINKIEL, M, additional, AVILA, V, additional, BENVEGNÚ, C, additional, BONELLI, AL, additional, BRENZONI, P, additional, BURGAR, M, additional, BUSSETTI, J, additional, CANOVAS, E, additional, CHAZARRETA, A, additional, CUCCHI, ME, additional, DEVALLE, ML, additional, FABBRO, D, additional, FARES TAIE, S, additional, GALVEZ, P, additional, GARCIA, R, additional, GIACCOBONI, D, additional, GÓMEZ, M, additional, GOTTA, G, additional, IZAGUIRRE, A, additional, LANDERRECHE, M, additional, LEZCANO, ML, additional, LOTERO POLESEL, D, additional, MIRA, R, additional, MURANO, MS, additional, NIETO, L, additional, PAZ , V, additional, PISSONI, C, additional, RAÑA, M, additional, RICCI, V, additional, SABATINI, M, additional, SALTOS, M, additional, SINGH, L, additional, SOTERAS, S, additional, SUPINO, C, additional, TEVEZ, I, additional, TORRES, F, additional, TORRES, MC, additional, VILLAGGI VIÑUELA , C, additional, WARGON , V, additional, YABBUR , MS, additional, and ZAWADA , L, additional
- Published
- 2019
- Full Text
- View/download PDF
40. Hepatectomy with or without the thoraco-abdominal approach: impact on perioperative outcome
- Author
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Mimmo, A., primary, Donadon, M., additional, Cosola, D., additional, Terrone, A., additional, Procopio, F., additional, Del Fabbro, D., additional, Cimino, M., additional, Viganò, L., additional, and Torzilli, G., additional
- Published
- 2019
- Full Text
- View/download PDF
41. Is Tumor detachment from vascular structures a technical option for intrahepatic cholangiocarcinoma?
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Vigano, L., primary, Fontana, A., additional, Procopio, F., additional, Terrone, A., additional, Cimino, M., additional, Donadon, M., additional, Del Fabbro, D., additional, and Torzilli, G., additional
- Published
- 2019
- Full Text
- View/download PDF
42. Prognostic determinants in patients with multiple colorectal liver metastases: the relevance of the primary tumor features
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Vigano, L., primary, Darwish, S.S., additional, Procopio, F., additional, Galvanin, J., additional, Cimino, M., additional, Donadon, M., additional, Del Fabbro, D., additional, and Torzilli, G., additional
- Published
- 2019
- Full Text
- View/download PDF
43. Individualized risk estimation for postoperative morbidity after hepatectomy: The Humanitas score.
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Donadon, M., primary, Fontana, A., additional, Palmisano, A., additional, Viganò, L., additional, Procopio, F., additional, Cimino, M., additional, Del Fabbro, D., additional, and Torzilli, G., additional
- Published
- 2019
- Full Text
- View/download PDF
44. Survival after hepatectomy for combined hepatocellular-cholangiocarcinoma: a case-match analysis with hepatocellular carcinoma and cholangiocarcinoma
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Mimmo, A., primary, Donadon, M., additional, Silvestri, M., additional, Viganò, L., additional, Del Fabbro, D., additional, Procopio, F., additional, Cimino, M., additional, Di Tommaso, L., additional, Roncalli, M., additional, and Torzilli, G., additional
- Published
- 2019
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- View/download PDF
45. The behavior of colorectal liver metastases in the interval between the end of chemotherapy and liver resection. A new criterion to select patients
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Vigano, L., primary, Darwish, S.S., additional, Cimino, M., additional, Donadon, M., additional, Procopio, F., additional, Del Fabbro, D., additional, and Torzilli, G., additional
- Published
- 2019
- Full Text
- View/download PDF
46. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview
- Author
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Alexander, S.P., Kelly, E., Marrion, N.V., Peters, J.A., Faccenda, E., Harding, S.D., Pawson, A.J., Sharman, J.L., Southan, C., Buneman, O.P., Cidlowski, J.A., Christopoulos, A., Davenport, A.P., Fabbro, D., Spedding, M., Striessnig, J., Davies, J.A., CGTP Collaborators, Abbracchio, M.P., Aldrich, R., Al-Hosaini, K., Arumugam, T.V., Attali, B., Bäck, M., Barnes, N.M., Bathgate, R., Beart, P.M., Becirovic, E., Bettler, B., Biel, M., Birdsall, N.J., Blaho, V., Boison, D., Bräuner-Osborne, H., Bröer, S., Bryant, C., Burnstock, G., Calo, G., Catterall, W.A., Ceruti, S., Chan, S.L., Chandy, K.G., Chazot, P., Chiang, N., Chun, J.J., Chung, J.J., Clapham, D.E., Clapp, L., Connor, M.A., Cox, H.M., Davies, P., Dawson, P.A., Decaen, P., Dent, G., Doherty, P., Douglas, S.D., Dubocovich, M.L., Fong, T.M., Fowler, C.J., Frantz, A., Fuller, P., Fumagalli, M., Futerman, A.H., Gainetdinov, R.R., Gershengorn, M.A., Goldin, A., Goldstein, S., Goudet, C., Gregory, K., Grissmer, S., Gundlach, A.L., Hagenbuch, B., Hamann, J., Hammond, J.R., Hancox, J.C., Hanson, J., Hanukoglu, I., Hay, D.L., Hobbs, A.J., Hollenberg, A.N., Holliday, N.D., Hoyer, D., Ijzerman, A.P., Inui, K.I., Irving, A.J., Ishii, S., Jacobson, K.A., Jan, L.Y., Jarvis, M.F., Jensen, R., Jockers, R., Kaczmarek, L.K., Kanai, Y., Karnik, S., Kellenberger, S., Kemp, S., Kennedy, C., Kerr, I.D., Kihara, Y., Kukkonen, J., Larhammar, D., Leach, K., Lecca, D., Leeman, S., Leprince, J., Lolait, S.J., Macewan, D., Maguire, J.J., Marshall, F., Mazella, J., Mcardle, C.A., Michel, M.C., Miller, L.J., Mitolo, V., Mizuno, H., Monk, P.N., Mouillac, B., Murphy, P.M., Nahon, J.L., Nerbonne, J., Nichols, C.G., Norel, X., Offermanns, S., Palmer, L.G., Panaro, M.A., Papapetropoulos, A., Perez-Reyes, E., Pertwee, R.G., Pintor, S., Pisegna, J.R., Plant, L.D., Poyner, D.R., Prossnitz, E.R., Pyne, S., Ramachandran, R., Ren, D., Rondard, P., Ruzza, C., Sackin, H., Sanger, G., Sanguinetti, M.C., Schild, L., Schiöth, H., Schulte, G., Schulz, S., Segaloff, D.L., Serhan, C.N., Singh, K.D., Slesinger, P.A., Snutch, T.P., Sobey, C.G., Stewart, G., Stoddart, L.A., Summers, R.J., Szabo, C., Thwaites, D., Toll, L., Trimmer, J.S., Tucker, S., Vaudry, H., Verri, T., Vilargada, J.P., Waldman, S.A., Ward, D.T., Waxman, S.G., Wei, A.D., Willars, G.B., Wong, S.S., Woodruff, T.M., Wulff, H., Ye, R.D., Yung, Y., and Zajac, J.M.
- Subjects
Databases, Pharmaceutical ,Humans ,Knowledge Bases ,Ligands ,Proteins - Abstract
The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13882/full. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
- Published
- 2017
47. The concise guide to pharmacology 2017/18: Overview
- Author
-
Alexander, S.P.H., Kelly, E., Marrion, N.V., Peters, J.A., Faccenda, E., Harding, S.D., Pawson, A.J., Sharman, J.L., Southan, C., Buneman, O.P., Cidlowski, J.A., Christopoulos, A., Davenport, A.P., Fabbro, D., Spedding, M., Striessnig, J., Davies, J.A., and IJzerman, A.P.
- Abstract
The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13882/full. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
- Published
- 2017
48. Imatinib: a selective tyrosine kinase inhibitor
- Author
-
Manley, P.W., Cowan-Jacob, S.W., Buchdunger, E., Fabbro, D., Fendrich, G., Furet, P., Meyer, T., and Zimmermann, J.
- Published
- 2002
- Full Text
- View/download PDF
49. Immunocytochemical expression of tissue specific transcription factor-1 in lung carcinoma
- Author
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Di Loreto, C, Di Lauro, V, Puglisi, F, Damante, G, Fabbro, D, and Beltrami, C A
- Published
- 1997
50. Search for Charged Higgs Bosons Produced via Vector Boson Fusion and Decaying into a Pair of W and Z Bosons Using pp Collisions at root s=13 TeV
- Author
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Sirunyan, and Tumasyan, A. M., and Adam, A., and Asilar, W., and Bergauer, E., and Brandstetter, T., and Brondolin, J., and Dragicevic, E., and Eroe, M., and Flechl, J., and Friedl, M., and Fruhwirth, M., and Ghete, R., and Hartl, V. M., and Hormann, C., and Hrubec, N., and Jeitler, J., and Koenig, M., and Kratschmer, A., and Liko, I., and Matsushita, D., and Mikulec, T., and Rabady, I., and Rad, D., and Rahbaran, N., and Rohringer, B., and Schieck, H., and Strauss, J., and Waltenberger, J., and Wulz, W., and Dvornikov, C. -E., and Makarenko, O., and Mossolov, V., and Gonzalez, V., Suarez and Zykunov, J., and Shumeiko, V., and Alderweireldt, N., and De Wolf, S., and Janssen, E. A., and Lauwers, X., and Van De Klundert, J., and Van Haevermaet, M., and Van Mechelen, H., and Van Remortel, P., and Van Spilbeeck, N., and Abu Zeid, A., and Blekman, S., and D'Hondt, F., and Daci, J., and De Bruyn, N., and Deroover, I., and Lowette, K., and Moortgat, S., and Moreels, S., and Olbrechts, L., and Python, A., and Skovpen, Q., and Tavernier, K., and Van Doninck, S., and Van Mulders, W., and Van Parijs, P., and Brun, I., and Clerbaux, H., and De Lentdecker, B., and Delannoy, G., and Fasanella, H., and Favart, G., and Goldouzian, L., and Grebenyuk, R., and Karapostoli, A., and Lenzi, G., and Leonard, T., and Luetic, A., and Maerschalk, J., and Marinov, T., and Randle-Conde, A., and Seva, A., and Velde, T., Vander and Vanlaer, C., and Vannerom, P., and Yonamine, D., and Zenoni, R., and Zhang, F., and Cornelis, F., and Dobur, T., and Fagot, D., and Gul, A., and Khvastunov, M., and Poyraz, I., and Salva, D., and Schofbeck, S., and Tytgat, R., and Van Driessche, M., and Verbeke, W., and Zaganidis, W., and Bakhshiansohi, N., and Bondu, H., and Brochet, O., and Bruno, S., and Caudron, G., and De Visscher, A., and Delaere, S., and Delcourt, C., and Francois, M., and Giammanco, B., and Jafari, A., and Komm, A., and Krintiras, M., and Lemaitre, G., and Magitteri, V., and Mertens, A., and Musich, A., and Piotrzkowski, M., and Quertenmont, K., and Marono, L., Vidal and Wertz, M., and Beliy, S., and Alda Junior, N., and Alves, W. L., and Alves, F. L., and Brito, G. A., and Hensel, L., and Moraes, C., and Pol, A., and Rebello Teles, M. E., and Belchior Batista Das Chagas, P., and Carvalho, E., and Chinellato, W., and Custodio, J., and Da Costa, A., and Da Silveira, E. M., and De Jesus Damiao, G. G., and De Oliveira Martins, D., and Fonseca De Souza, C., and Huertas Guativa, S., and Malbouisson, L. M., and Matos Figueiredo, H., and Mora Herrera, D., and Mundim, C., and Nogima, L., and Prado Da Silva, H., and Santoro, W. L., and Sznajder, A., and Tonelli Manganote, A., and Torres Da Silva De Araujo, E. J., and Vilela Pereira, F., and Ahuja, A., and Bernardes, S., and Dogra, C. A., and Fernandez Perez Tomei, S., and Gregores, T. R., and Mercadante, E. M., and Moon, P. G., and Novaes, C. S., and Padula, S. F., and Romero Abad, Sandra S., and Ruiz Vargas, D., and Aleksandrov, J. C., and Hadjiiska, A., and Iaydjiev, R., and Rodozov, P., and Stoykova, M., and Sultanov, S., and Vutova, G., and Dimitrov, M., and Glushkov, A., and Litov, I., and Pavlov, L., and Petkov, B., and Fang, P., and Gao, W., and Ahmad, X., and Bian, M., and Chen, J. G., and Chen, G. M., and Chen, H. S., and Chen, M., and Cheng, Y., and Jiang, T., and Leggat, C. H., and Liu, D., and Romeo, Z., and Ruan, F., and Shaheen, M., and Spiezia, S. M., and Tao, A., and Wang, J., and Wang, C., and Yazgan, Z., and Zhang, E., and Zhao, H., and Ban, J., and Chen, Y., and Li, G., and Liu, Q., and Mao, S., and Qian, Y., and Wang, S. J., and Xu, D., and Avila, Z., and Cabrera, C., and Chaparro Sierra, A., and Florez, L. F., and Gomez, C., and Gonzalez Hernandez, J. P., and Ruiz Alvarez, C. F., and Sanabria, J. D., and Godinovic, J. C., and Lelas, N., and Puljak, D., and Cipriano, I., Ribeiro and Sculac, P. M., and Antunovic, T., and Kovac, Z., and Brigljevic, M., and Ferencek, V., and Kadija, D., and Mesic, K., and Susa, B., and Ather, T., and Attikis, M. W., and Mavromanolakis, A., and Mousa, G., and Nicolaou, J., and Ptochos, C., and Razis, F., and Rykaczewski, P. A., and Finger, H., and Finger, M., J, R., and Jarrin, M., Carrera and Abdelalim, E., and Mohammed, A. A., and Salama, Y., and Kadastik, E., and Perrini, M., and Raidal, L., and Tiko, M., and Veelken, A., and Eerola, C., and Pekkanen, P., and Voutilainen, J., and Hakonen, M., and Jarvinen, J., and Karimki, T., and Kinnunen, V., and Lampen, R., and Lassila-Perini, T., and Lehti, K., and Linden, S., and Luukka, T., and Tuominiemi, P., and Tuovinen, J., and Wendland, E., and Talvitie, L., and Tuuva, J., and Besancon, T., and Couderc, M., and Dejardin, F., and Denegri, M., and Fabbro, D., and Faure, B., and Favaro, J. L., and Ganjour, C., and Ghosh, S., and Givernaud, S., and Gras, A., and de Monchenault, P., Hamel and Jarry, G., and Kucher, P., and Locci, I., and Machet, E., and Malcles, M., and Rander, J., and Rosowsky, J., and Titov, A., and Abdulsalam, M., and Antropov, A., and Baffioni, I., and Beaudette, S., and Busson, F., and Cadamuro, P., and Chapon, L., and Charlot, E., and Davignon, C., and de Cassagnac, O., Granier and Jo, R., and Lisniak, M., and Lobanov, S., and Mine, A., and Nguyen, P., and Ochando, M., and Ortona, C., and Paganini, G., and Pigard, P., and Regnard, P., and Salerno, S., and Sirois, R., and Leiton, Y., Stahl and Strebler, A. G., and Yilmaz, T., and Zabi, Y., and Zghiche, A., and Agram, A., and Andrea, J. -L., and Bloch, J., and Brom, D., and Buttignol, J. -M., and Chabert, M., and Chanon, E. C., and Collard, N., and Conte, C., and Coubez, E., and Fontaine, X., and Gele, J. -C., and Goerlach, D., and Le Bihan, U., and Van Hove, A. -C., and Gadrat, P., and Beauceron, S., and Bernet, S., and Boudoul, C., and Montoya, G., Carrillo and Chierici, C. A., and Contardo, R., and Courbon, D., and Depasse, B., and El Mamouni, P., and Fay, H., and Finco, J., and Gascon, L., and Gouzevitch, S., and Grenier, M., and Ille, G., and Lagarde, B., and Laktineh, F., and Lethuillier, I. B., and Mirabito, M., and Pequegnot, L., and Perries, A. L., and Popov, S., and Sordini, A., and Donckt, V., Vander and Verdier, M., and Viret, P., and Khvedelidze, S., and Tsamalaidze, A., and Autermann, Z., and Beranek, C., and Feld, S., and Kiesel, L., and Klein, M. 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- Subjects
transverse momentum: missing-energy ,13000 GeV-cms ,NEUTRINO MASSES ,ATLAS DETECTOR ,final state: ((n)jet 3lepton) ,vector boson: fusion ,ddc:550 ,scattering [p p] ,((n)jet 3lepton) [final state] ,Nuclear Experiment ,Neutrino Masses ,Broken Symmetries ,Gauge ,Mixings ,Models ,Weak ,High energy physics ,Tellurium compounds ,Bosons ,Higgs bosons ,02 Physical Sciences ,PARITY ,CMS ,Physics ,Settore FIS/01 - Fisica Sperimentale ,triplet [model] ,Vector Boson Fusion ,mass dependence ,channel cross section: branching ratio: upper limit ,CERN LHC Coll ,Physical Sciences ,CMS Collaboration ,SYMMETRIES ,Centre for High Energy Physics ,charged particle [Higgs particle] ,MIXINGS ,LHC ,colliding beams [p p] ,Higgs particle: triplet ,LEFT-RIGHT SYMMETRY ,MASSLESS PARTICLES ,BROKEN ,GAUGE ,VIOLATION ,MODEL ,dijet: mass ,p p: scattering ,General Physics ,Higgs boson ,Higgs particle: charged particle ,MODELS ,Physics, Multidisciplinary ,Physics and Astronomy (all) ,proton-proton collisions ,fusion [vector boson] ,NEUTRINO MASSES, BROKEN SYMMETRIES, GAUGE, MIXINGS, MODELS, WEAK ,mass [dijet] ,BROKEN SYMMETRIES ,model: triplet ,CMS DETECTOR ,triplet [Higgs particle] ,Science & Technology ,branching ratio: upper limit [channel cross section] ,High Energy Physics::Phenomenology ,Aerospace Engineering(Formerly Aeronautical Engineering) ,rapidity ,Physics and Astronomy ,Higgs ,LHC, Charged Higgs Bosons, Vector Boson Fusion, proton-proton collisions ,missing-energy [transverse momentum] ,High Energy Physics::Experiment ,WEAK ,p p: colliding beams ,experimental results - Abstract
Physical review letters 119(14), 141802 (2017). doi:10.1103/PhysRevLett.119.141802, Published by American Physical Society, College Park, Md.
- Published
- 2017
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