60 results on '"Fabbricatore D."'
Search Results
2. High efficacy single catheter standardized workflow for radiofrequency ablation of atrial fibrillation in the high-power short-duration era
- Author
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Valeriano, C, primary, Fabbricatore, D, additional, Verdonckt, L, additional, Buytaert, D, additional, De Schouwer, K, additional, De Braekeleer, L, additional, and De Potter, T, additional
- Published
- 2023
- Full Text
- View/download PDF
3. Evaluation of a fully automated anatomical left atrial mapping pipeline enabled by artficial intelligence
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Buytaert, D, primary, Valeriano, C, additional, Fabbricatore, D, additional, De Schouwer, K, additional, Peytchev, P, additional, Geelen, P, additional, and De Potter, T, additional
- Published
- 2023
- Full Text
- View/download PDF
4. Impact of aortic regurgitation on long-term outcomes in heart failure with preserved ejection fraction
- Author
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De Colle, C, primary, Paolisso, P, additional, Gallinoro, E, additional, Bertolone, D T, additional, Mileva, N, additional, Fabbricatore, D, additional, Valeriano, C, additional, Mancusi, C, additional, Collet, C, additional, Vanderheyden, M, additional, De Luca, N, additional, Van Camp, G, additional, Barbato, E, additional, Bartunek, J, additional, and Penicka, M, additional
- Published
- 2022
- Full Text
- View/download PDF
5. Microvascular dysfunction in patients with diabetes mellitus: assessment of absolute coronary flow and microvascular resistance reserve
- Author
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Paolisso, P, primary, Gallinoro, E, additional, Belmonte, M, additional, Bertolone, D T, additional, Bermpeis, K, additional, Esposito, G, additional, Seki, R, additional, Fabbricatore, D, additional, Bartunek, J, additional, Vanderheyden, M, additional, Wyffels, E, additional, Sonck, J, additional, Collet, C, additional, De Bruyne, B, additional, and Barbato, E, additional
- Published
- 2022
- Full Text
- View/download PDF
6. Prevalence of atrial fibrillation and feasibility of pulmonary vein isolation after patent foramen ovale closure
- Author
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Fabbricatore, D, primary, Paolisso, P P, additional, Gallinoro, E G, additional, De Colle, C D C, additional, Valeriano, C V, additional, De Schouwer, K D S, additional, Geelen, P G, additional, Barbato, E B, additional, and De Potter, T D P, additional
- Published
- 2022
- Full Text
- View/download PDF
7. Risk factors for gram-negative infection of cardiovascular implantable electronic devices: retrospective multicenter study - CarDINe study
- Author
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Pascale, R, primary, Abdullah, TA, additional, Fabbricatore, D, additional, De Potter, T, additional, Ripa, M, additional, Durante-Mangoni, E, additional, Leventopulos, G, additional, Domenichini, G, additional, Iacopino, S, additional, Akova, M, additional, Diemberger, I, additional, Viale, P, additional, and Giannella, M, additional
- Published
- 2022
- Full Text
- View/download PDF
8. Ambulatory pulmonary vein isolation workflow using suture-mediated vascular closure devices: a prospective observational cohort study
- Author
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Fabbricatore, D, primary, Mileva, N, additional, Valeriano, C, additional, Buytaert, D, additional, Paolisso, P, additional, Geelen, P, additional, and De Potter, T, additional
- Published
- 2022
- Full Text
- View/download PDF
9. Performance of non-invasive myocardial work to predict the first hospitalization for de novo heart failure with preserved ejection fraction (HFpEF)
- Author
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Paolisso, P, primary, Gallinoro, E, additional, Mileva, N, additional, Moya, A, additional, Fabbricatore, D, additional, Esposito, G, additional, De Colle, C, additional, Spapen, J, additional, Heggermont, W, additional, Collet, C, additional, Van Camp, G, additional, Vanderheyden, M, additional, Barbato, E, additional, Bartunek, J, additional, and Penicka, M, additional
- Published
- 2022
- Full Text
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10. Angiography vs physiology-based deferral of revascularization in patients with reduced left ventricular ejection fraction: a 10-year clinical follow-up
- Author
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Gallinoro, E, primary, Paolisso, P, additional, Bermpeis, K, additional, Peregrina, E F, additional, Candreva, A, additional, Esposito, G, additional, Fabbricatore, D, additional, Sonck, J, additional, Di Gioia, G, additional, Vanderheyden, M, additional, Bartunek, J, additional, Collet, C, additional, De Bruyne, B, additional, and Barbato, E, additional
- Published
- 2021
- Full Text
- View/download PDF
11. Effects of Bronchoscopic Lung Volume Reduction on Heart-Lung Interaction in COPD Patients with Severe Pulmonary Emphysema
- Author
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Spreafico, F., primary, Novali, M., additional, Vizzardi, E., additional, Fabbricatore, D., additional, Bertolovic, L., additional, Bezzi, M., additional, and Tantucci, C., additional
- Published
- 2020
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12. Leadless pacemaker: State of the art and incoming developments to broaden indications
- Author
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Curnis, A., Salghetti, F, Cerini, M., Fabbricatore, D., Ghizzoni, G., Arabia, G., Maiolo, V., Albpolhassan, M, and Bontempi, L.
- Published
- 2020
13. Technical considerations for CRT-D implantation in different varietesof persistent left superior vena cava
- Author
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Bontempi, L, Aboelhassan, M, Cerini, M, Salghetti, F, Fabbricatore, D, Maiolo, V, Ghizzoni, G, and Curnis, A.
- Published
- 2020
14. Atrial septal defects, supravalvular aortic stenosis and syndromes predisposing to aneurysm of large vessels
- Author
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Baglivo, M., Dassati, S., Krasi, G., Fanelli, F., Kurti, D., Bonelli, A., Arabia, G., Fabbricatore, D., Muneretto, C., Bertelli, M., and Paolacci, S.
- Subjects
Atrial ,Heart Septal Defects ,High-Throughput Nucleotide Sequencing ,Review ,Aneurysm ,Heart Septal Defects, Atrial ,Aneurysm of large vessels ,Aortic Stenosis, Supravalvular ,Supravalvular ,Supravalvular aortic stenosis ,cardiovascular system ,Atrial septal defect ,Humans ,Genetic Predisposition to Disease ,Genetic Testing ,Aortic Stenosis - Abstract
Atrial septal defect is a persistent interatrial communication. It is the second most common congenital heart defect and is detected in 1:1500 live births. Clinical course is variable and depends on the size of the malformation. Clinical diagnosis is based on patient history, physical and instrumental examination. Atrial septal defect is frequently sporadic, but familial cases have been reported. The disease has autosomal dominant inheritance with reduced penetrance, variable expressivity and genetic heterogeneity. Supravalvular aortic stenosis is a congenital narrowing of the lumen of the ascending aorta. It has an incidence of 1:20000 newborns and a prevalence of 1:7500. Clinical diagnosis is based on patient history, physical and instrumental examination. Supravalvular aortic stenosis is either sporadic or familial and has autosomal dominant inheritance with reduced penetrance and variable expressivity. It is associated with mutations in the ELN gene. Syndromes predisposing to aneurysm of large vessels is a group of inherited disorders that may affect different segments of the aorta. They may occur in isolation or associated with other genetic syndromes. Clinical symptoms are highly variable. Familial thoracic aortic aneurysm and dissection accounts for ~20% of all cases of aneurysms. The exact prevalence is unknown. Clinical diagnosis is based on medical history, physical and instrumental examination. Genetic testing is useful for confirming diagnosis of these syndromes and for differential diagnosis, recurrence risk evaluation and prenatal diagnosis in families with a known mutation. Most syndromes predisposing to aneurysm of large vessels have autosomal dominant inheritance with reduced penetrance and variable expressivity. (www.actabiomedica.it)
- Published
- 2019
15. P4234A telemonitoring program for screening and primary and secondary prevention of cardiovascular disease
- Author
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Lupi, L, primary, Glisenti, F, additional, Papa, I, additional, Arabia, G, additional, Piazzani, M, additional, Fabbricatore, D, additional, Castiello, A, additional, Madureri, A, additional, and Nodari, S, additional
- Published
- 2018
- Full Text
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16. Prognostic Evaluation Of The Ascending Aorta's Elastic Properties In Patients With Non-Ischemic Dilated Cardiomyopathy: An Echocardiographic Long-Term Follow-Up Study
- Author
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Vizzardi, E., Sciatti, E., Bonadei, I., Carubelli, V., Lombardi, C., Gavazzoni, M., Prati, F., Fabbricatore, D., Perego, C., Ravera, A., Ferizi, R., and Metra, Marco
- Published
- 2017
17. The Additional Role Of Diabetes Mellitus On Hypertension-Related Aortic Stiffness
- Author
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Sciatti, E., Vizzardi, E., Valentini, F., Castiello, A., Cotugno, Annunziata, Fabbricatore, D., Ferizi, R., Masini, Gabriele, Bonadei, I., Lombardi, C., Raddino, R., and Metra, M.
- Published
- 2017
18. Elastic Aortic Properties In Cystic Fibrosis Adults Without Cardiovascular Risk Factors: A Case-Control Study
- Author
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Vizzardi, E., Sciatti, E., Bonadei, I., Cani, D., Fabbricatore, D., Cotugno, A., Menotti, E., Berlendis, M., Padoan, R., and Metra, Marco
- Published
- 2017
19. Measurement of the cross section for production of bb¯X decaying to muons in pp collisions at √s = 7 TeV
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Chatrchyan, S., Khachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Bergauer, T., Dragicevic, M., Erö, J., Fabjan, C., Friedl, M., Frühwirth, R., Ghete, V. M., Hammer, J., Hoch, M., Hörmann, N., Hrubec, J., Jeitler, M., Kiesenhofer, W., Krammer, M., Liko, D., Mikulec, I., Pernicka, M., Rahbaran, B., Rohringer, C., Rohringer, H., Schöfbeck, R., Strauss, J., Taurok, A., Teischinger, F., Wagner, P., Waltenberger, W., Walzel, G., Widl, E., Wulz, C. E., Mossolov, V., Shumeiko, N., Suarez, Gonzalez, Bansal, J., Benucci, S., Cornelis, L., Wolf, De, E. A., Janssen, Luyckx, X., Maes, S., Mucibello, T., Ochesanu, L., Roland, S., Rougny, B., Selvaggi, R., Van, Haevermaet, Van, Mechelen, Van, Remortel, Van, Spilbeeck, Blekman, A., Blyweert, F., D'Hondt, S., Gonzalez, Suarez, Kalogeropoulos, R., Maes, A., Olbrechts, M., Van, Doninck, Van, Mulders, Van, Onsem, G. P., Villella, Charaf, I., Clerbaux, O., Lentdecker, De, Dero, G., Gay, V., A. P. R., Hammad, G. H., Hreus, Léonard, T., Marage, A., P. E., Thomas, Vander, Velde, Vanlaer, C., Wickens, P., Adler, J., Beernaert, V., Cimmino, K., Costantini, A., Garcia, S., Grunewald, G., Klein, M., Lellouch, B., Marinov, J., Mccartin, A., Ocampo, Rios, A. A., Ryckbosch, Strobbe, D., Thyssen, N., Tytgat, F., Vanelderen, M., Verwilligen, L., Walsh, P., Yazgan, S., Zaganidis, E., Basegmez, N., Bruno, S., Ceard, G., De Favereau De Jeneret, Delaere, J., Pree, Du, Favart, T., Forthomme, D., Giammanco, L., Grégoire, A., Hollar, G., Lemaitre, J., Liao, V., Militaru, J., Nuttens, O., Pagano, C., Pin, D., Piotrzkowski, A., Schul, K., Beliy, N., Caebergs, N., Daubie, T., Alves, E., G. A., Correa Martins, J. r., De Jesus Damiao, Martins, D., Pol, T., E. M., Souza, M. H. G., Aldá, J. r., W. L., Carvalho, Custódio, W., Costa, Da, E. M., De Oliveira Martins, Fonseca De Souza, Matos, Figueiredo, Mundim, D., Nogima, L., Oguri, H., Prado Da Silva, W. L., Santoro, Silva Do Amaral, S. M., Soares, Jorge, Sznajder, L., Anjos, A., T. S., Bernardes, C. A., Dias, F. A., Fernandez Perez Tomei, T. R., Gregores, E. M., Lagana, Marinho, C., Mercadante, F., P. G., Novaes, S. F., Padula, S. S., Genchev, Iaydjiev, V., Piperov, P., Rodozov, S., Stoykova, M., Sultanov, S., Tcholakov, G., Trayanov, V., Vutova, R., Dimitrov, M., Hadjiiska, A., Karadzhinova, R., Kozhuharov, A., Litov, V., Pavlov, L., Petkov, B., Bian, P., J. G., Chen, G. M., Chen, H. S., Jiang, C. H., Liang, Liang, D., Meng, S., Tao, X., Wang, J., Wang, X., Xiao, Z., Xu, H., Zang, M., Zhang, J., Asawatangtrakuldee, Z., Ban, C., Guo, Y., Guo, S., Li, Y., Liu, W., Mao, S., Qian, Y., J. S., Teng, Wang, H., Zhu, S., Zou, B., Cabrera, W., Gomez, Moreno, Osorio, Oliveros, A. F., Sanabria, J. C., Godinovic, Lelas, N., Plestina, D., Polic, R., Puljak, D., Antunovic, I., Dzelalija, Z., Kovac, M., Brigljevic, M., Duric, V., Kadija, S., Luetic, K., Morovic, J., Attikis, S., Galanti, A., Mousa, M., Nicolaou, J., Ptochos, C., Razis, F., P. A., Finger, Finger, J. r., Assran, M., Ellithi, Kamel, Khalil, A., Mahmoud, S., M. A., Radi, Hektor, A., Kadastik, A., Müntel, M., Raidal, M., Rebane, M., Tiko, L., Azzolini, A., Eerola, V., Fedi, P., Voutilainen, G., Czellar, M., Härkönen, S., Heikkinen, J., Karimäki, A., Kinnunen, V., Kortelainen, R., M. J., Lampén, Lassila, Perini, Lehti, K., Lindén, S., Luukka, T., Mäenpää, P., Peltola, T., Tuominen, T., Tuominiemi, E., Tuovinen, J., Ungaro, E., Wendland, D., Banzuzi, L., Korpela, K., Tuuva, A., Sillou, T., Besancon, D., Choudhury, M., Dejardin, S., Denegri, M., Fabbro, D., Faure, B., L. J., Ferri, Ganjour, F., Givernaud, S., Gras, A., Hamel De Monchenault, Jarry, G., Locci, P., Malcles, E., Millischer, J., Rander, L., Rosowsky, J., Shreyber, A., Titov, I., Baffioni, M., Beaudette, S., Benhabib, F., Bianchini, L., Bluj, L., Broutin, M., Busson, C., Charlot, P., Daci, C., Dahms, N., Dobrzynski, T., Elgammal, L., Granier De Cassagnac, Haguenauer, R., Miné, M., Mironov, P., Ochando, C., Paganini, C., Sabes, P., Salerno, D., Sirois, R., Thiebaux, Y., Veelken, C., Zabi, C., Agram, A., J. L., Andrea, Bloch, J., Bodin, D., Brom, D., J. M., Cardaci, Chabert, M., E. C., Collard, Conte, C., Drouhin, E., Ferro, F., Fontaine, C., J. C., Gelé, Goerlach, D., Juillot, U., Karim, P., Bihan, Le, A. C., Van, Hove, Fassi, P., Mercier, F., Baty, D., Beauceron, C., Beaupere, S., Bedjidian, N., Bondu, M., Boudoul, O., Boumediene, G., Brun, D., Chasserat, H., Chierici, J., Contardo, R., Depasse, D., Mamouni, El, Falkiewicz, H., Fay, A., Gascon, J., Gouzevitch, S., Ille, M., Kurca, B., Grand, Le, Lethuillier, T., Mirabito, M., Perries, L., Sordini, S., Tosi, V., Tschudi, S., Verdier, Y., Viret, P., Lomidze, S., Anagnostou, D., Beranek, G., Edelhoff, S., Feld, M., Heracleous, L., Hindrichs, N., Jussen, O., Klein, R., Merz, K., Ostapchuk, J., Perieanu, A., Raupach, A., Sammet, F., Schael, J., Sprenger, S., Weber, D., Wittmer, H., Zhukov, B., Ata, V., Caudron, M., Dietz, Laursonn, Erdmann, E., Güth, M., Hebbeker, A., Heidemann, T., Hoepfner, C., Klimkovich, K., Klingebiel, T., Kreuzer, D., Lanske, P., Lingemann, D., Magass, J., Merschmeyer, C., Meyer, M., Olschewski, A., Papacz, M., Pieta, P., Reithler, H., Schmitz, H., S. A., Sonnenschein, Steggemann, L., Teyssier, J., Bontenackels, M., Cherepanov, M., Davids, V., Flügge, M., Geenen, G., Geisler, H., Haj, Ahmad, Hoehle, W., Kargoll, F., Kress, B., Kuessel, T., Linn, Y., Nowack, A., Perchalla, A., Pooth, L., Rennefeld, O., Sauerland, J., Stahl, P., Zoeller, A., M. H., Aldaya, Martin, Behrenhoff, M., Behrens, W., Bergholz, U., Bethani, M., Borras, A., Burgmeier, K., Cakir, A., Calligaris, A., Campbell, L., Castro, A., Dammann, E., Eckerlin, D., Eckstein, G., Flossdorf, D., Flucke, A., Geiser, G., Hauk, A., Jung, J., Kasemann, H., Katsas, M., Kleinwort, P., Kluge, C., Knutsson, H., Krämer, A., Krücker, M., Kuznetsova, D., Lange, E., Lohmann, W., Lutz, W., Mankel, B., Marfin, R., Marienfeld, I., Melzer, Pellmann, I. A., Meyer, A. B., Mnich, Mussgiller, J., Naumann, Emme, Olzem, S., Petrukhin, J., Pitzl, A., Raspereza, D., Ribeiro, Cipriano, P. M., Rosin, Salfeld, Nebgen, Schmidt, J., Schoerner, Sadenius, Sen, T., Spiridonov, N., Stein, A., Tomaszewska, M., Walsh, J., Wissing, R., Autermann, C., Blobel, C., Bobrovskyi, V., Draeger, S., Enderle, J., Ere, H., Gebbert, J., Görner, U., Hermanns, M., Höing, T., R. S., Kaschube, Kaussen, K., Kirschenmann, G., Klanner, H., Lange, R., Mura, J., Nowak, B., Pietsch, F., Sander, N., Schettler, C., Schleper, H., Schlieckau, P., Schmidt, E., Schröder, A., Schum, M., Stadie, T., Steinbrück, H., Thomsen, G., Barth, J., Berger, C., Chwalek, J., Boer, De, Dierlamm, W., Dirkes, A., Feindt, G., Gruschke, M., Guthoff, J., Hackstein, M., Hartmann, C., Heinrich, F., Held, M., Hoffmann, H., K. H., Honc, Katkov, S., Komaragiri, I., R. J., Kuhr, Martschei, T., Mueller, D., Müller, S., T. h., Niegel, Nürnberg, M., Oberst, A., Oehler, O., Ott, A., Peiffer, J., Quast, T., Rabbertz, G., Ratnikov, K., Ratnikova, F., Renz, N., Röcker, M., Saout, S., Scheurer, C., Schieferdecker, A., Schilling, P., F. P., Schmanau, Schott, M., Simonis, G., H. J., Stober, F. M., Troendle, Wagner, Kuhr, Weiler, J., Zeise, T., Ziebarth, M., E. B., Daskalakis, Geralis, G., Kesisoglou, T., Kyriakis, S., Loukas, A., Manolakos, D., Markou, I., Markou, A., Mavrommatis, C., Ntomari, C., Gouskos, E., Mertzimekis, L., T. J., Panagiotou, Saoulidou, A., Stiliaris, N., Evangelou, E., Foudas, I., Kokkas, C., Manthos, P., Papadopoulos, N., Patras, I., Triantis, V., F. A., Aranyi, Bencze, A., Boldizsar, G., Hajdu, L., Hidas, C., Horvath, P., Kapusi, D., Krajczar, A., Sikler, K., Veszpremi, F., Vesztergombi, V., Beni, G., Molnar, N., Palinkas, J., Szillasi, J., Karancsi, Z., Raics, J., Trocsanyi, P., L. Z., Ujvari, Beri, B., S. B., Bhatnagar, Dhingra, V., Gupta, N., Jindal, R., Kaur, M., Kohli, M., J. M., Mehta, M. Z., Nishu, Saini, N., L. K., Sharma, Singh, A., A. P., Singh, Singh, J., S. P., Ahuja, Choudhary, S., B. C., Kumar, Kumar, A., Malhotra, A., Naimuddin, S., Ranjan, M., Sharma, K., Shivpuri, V., R. K., Banerjee, Bhattacharya, S., Dutta, S., Gomber, S., Jain, B., Khurana, S., Sarkar, R., Choudhury, S., R. K., Dutta, Kailas, D., Kumar, S., Mohanty, V., A. K., Pant, L. M., Shukla, Aziz, P., Ganguly, T., Guchait, S., Gurtu, M., Maity, A., Majumder, M., Mazumdar, G., Mohanty, K., G. B., Parida, Saha, B., Sudhakar, A., Wickramage, K., Banerjee, N., Dugad, S., Mondal, S., N. K., Arfaei, Bakhshiansohi, H., Etesami, H., S. M., Fahim, Hashemi, A., Hesari, M., Jafari, H., Khakzad, A., Mohammadi, M., Mohammadi, Najafabadi, Paktinat, Mehdiabadi, Safarzadeh, S., Zeinali, B., Abbrescia, M., Barbone, M., Calabria, L., Chhibra, C., S. S., Colaleo, Creanza, A., Filippis, De, Palma, De, Fiore, M., Iaselli, L., Lusito, G., Maggi, L., Maggi, G., Manna, M., Marangelli, N., My, B., Nuzzo, S., Pacifico, S., Pompili, N., Pugliese, A., Romano, G., Selvaggi, F., Silvestris, G., Singh, L., Tupputi, G., Zito, S., Abbiendi, G., Benvenuti, G., A. C., Bonacorsi, Braibant, Giacomelli, Brigliadori, S., Capiluppi, L., Castro, P., Cavallo, A., F. R., Cuffiani, Dallavalle, M., G. M., Fabbri, Fanfani, F., Fasanella, A., Giacomelli, D., Grandi, P., Marcellini, C., Masetti, S., Meneghelli, G., Montanari, M., Navarria, A., F. L., Odorici, Perrotta, F., Primavera, A., Rossi, F., A. M., Rovelli, Siroli, T., Travaglini, G., Albergo, R., Cappello, S., Chiorboli, G., Costa, M., Potenza, S., Tricomi, R., Tuve, A., Barbagli, C., Ciulli, G., Civinini, V., D'Alessandro, C., Focardi, R., Frosali, E., Gallo, S., Gonzi, E., Meschini, S., Paoletti, M., Sguazzoni, S., Tropiano, G., Benussi, A., Bianco, L., Colafranceschi, S., Fabbri, S., Piccolo, F., Fabbricatore, D., Musenich, P., Benaglia, R., Guio, De, Matteo, Di, Fiorendi, L., Gennai, S., Ghezzi, S., Malvezzi, A., Manzoni, S., R. A., Martelli, Massironi, A., Menasce, A., Moroni, D., Paganoni, L., Pedrini, M., Ragazzi, D., Redaelli, S., Sala, N., Tabarelli De Fatis, Buontempo, T., Carrillo, Montoya, C. A., Cavallo, Cosa, De, Dogangun, A., Fabozzi, O., Iorio, F., A. O. M., Lista, Merola, L., Paolucci, M., Azzi, P., Bacchetta, P., Bellan, N., Bisello, P., Branca, D., Carlin, A., Checchia, R., Dorigo, P., Dosselli, T., Gasparini, U., Gasparini, F., Gozzelino, U., Kanishchev, A., Lacaprara, K., Lazzizzera, S., Margoni, I., Mazzucato, M., Meneguzzo, M., A. T., Montecassiano, Nespolo, F., Perrozzi, M., Pozzobon, L., Ronchese, N., Simonetto, P., Torassa, F., Tosi, E., Vanini, M., Zotto, S., Zumerle, P., Baesso, G., Berzano, P., Gabusi, U., Ratti, M., S. P., Riccardi, Torre, C., Vitulo, P., Viviani, P., Biasini, C., Bilei, M., G. M., Caponeri, Fanò, B., Lariccia, L., Lucaroni, P., Mantovani, A., Menichelli, G., Nappi, M., Romeo, A., Santocchia, F., Taroni, A., Valdata, S., Azzurri, M., Bagliesi, P., Boccali, G., Broccolo, T., Castaldi, G., D'Agnolo, R., R. T., Dell'Orso, Fiori, R., Foà, F., Giassi, L., Kraan, A., Ligabue, A., Lomtadze, F., Martini, T., Messineo, ALBERTO MARIA, Palla, F., Palmonari, F., Rizzi, Andrea, Serban, A. T., Spagnolo, P., Tenchini, R., Tonelli, GUIDO EMILIO, Venturi, A., Verdini, P. G., Barone, L., Cavallari, F., Del, Re, Diemoz, D., Fanelli, M., Franci, C., Grassi, D., Longo, M., Meridiani, E., Micheli, P., Nourbakhsh, F., Organtini, S., Pandolfi, G., Paramatti, F., Rahatlou, R., Sigamani, S., Soffi, M., Amapane, L., Arcidiacono, N., Argiro, R., Arneodo, S., Biino, M., Botta, C., Cartiglia, C., Castello, N., Costa, R., Demaria, M., Graziano, N., Mariotti, A., Maselli, C., Migliore, S., Monaco, E., Musich, V., Obertino, M., M. 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G., Huang, X. T., Lopez, Mendez, A., Oliveros, H., Ramirez, Vargas, J. E., Zatserklyaniy, Alagoz, A., Barnes, E., V. E., Benedetti, Bolla, D., Bortoletto, G., Mattia, De, Everett, M., Gutay, A., Hu, L., Jones, Z., Koybasi, M., Kress, O., Laasanen, M., A. T., Leonardo, Maroussov, N., Merkel, V., Miller, P., D. H., Neumeister, Shipsey, N., Silvers, I., Svyatkovskiy, D., Vidal, Marono, Yoo, M., H. D., Zablocki, Zheng, J., Guragain, Y., Parashar, S., Adair, N., Boulahouache, A., Cuplov, C., Ecklund, V., K. M., Geurts, F. J. M., Padley, B. P., Redjimi, Roberts, R., Zabel, J., Betchart, J., Bodek, B., Chung, A., Y. S., Covarelli, Barbaro, De, Demina, P., Eshaq, R., Garcia, Bellido, Goldenzweig, A., Gotra, P., Han, Y., Harel, J., Miner, A., D. C., Petrillo, Sakumoto, G., Vishnevskiy, W., Zielinski, D., Bhatti, M., Ciesielski, A., Demortier, R., Goulianos, L., Lungu, K., Malik, G., Mesropian, S., Arora, C., Atramentov, S., Barker, O., Chou, A., J. P., Contreras, Campana, Duggan, E., Ferencek, D., Gershtein, D., Gray, Y., Halkiadakis, R., Hidas, E., Hits, D., Lath, D., Panwalkar, A., Park, S., Patel, M., Richards, R., Rose, A., Salur, K., Schnetzer, S., Seitz, S., Somalwar, C., Stone, S., Thomas, R., Cerizza, S., Hollingsworth, G., Spanier, M., Z. C., York, Eusebi, A., Flanagan, R., Gilmore, W., Kamon, J., Khotilovich, T., Montalvo, V., Osipenkov, R., Pakhotin, I., Perloff, Y., Roe, A., Safonov, J., Sakuma, A., Sengupta, T., Suarez, S., Tatarinov, I., Toback, A., Akchurin, D., Bardak, N., Damgov, C., Dudero, J., P. R., Jeong, Kovitanggoon, C., Lee, K., S. W., Libeiro, Mane, T., Roh, P., Sill, Y., Volobouev, A., Wigmans, I., Appelt, R., Brownson, E., Engh, E., Florez, D., Gabella, C., Gurrola, W., Issah, A., Johns, M., Kurt, W., Maguire, P., Melo, C., Sheldon, A., Snook, P., Tuo, B., Velkovska, S., Arenton, J., M. W., Balazs, Boutle, M., Conetti, S., Cox, S., Francis, B., Goadhouse, B., Goodell, S., Hirosky, J., Ledovskoy, R., Lin, A., Neu, C., Wood, C., Yohay, J., Gollapinni, R., Harr, S., Karchin, R., P. E., Kottachchi Kankanamge Don, Lamichhane, C., Mattson, P., Milstène, M., Sakharov, C., Anderson, A., Bachtis, M., Belknap, M., Bellinger, D., J. N., Bernardini, Borrello, J., Carlsmith, L., Cepeda, D., Dasu, M., Efron, S., Friis, J., Gray, E., Grogg, L., K. S., Grothe, Hall, Wilton, Herndon, R., Hervé, M., Klabbers, A., Klukas, P., Lanaro, J., Lazaridis, A., Leonard, C., Loveless, J., Mohapatra, R., Ojalvo, A., Pierro, I., G. A., Ross, Savin, I., Smith, A., W. H., Swanson, wsky A, J., Shreyber, I, Titov, M, Baffioni, S, Beaudette, F, Benhabib, L, Bianchini, L, Bluj, M, Broutin, C, Busson, P, Charlot, C, Daci, N, Dahms, T, Dobrzynski, L, Elgammal, S, de Cassagnac RG, Haguenauer, M, Mine, P, Mironov, C, Ochando, C, Paganini, P, Sabes, D, Salerno, R, Sirois, Y, Thiebaux, C, Veelken, C, Zabi, A, Agram, Jl, Andrea, J, Bloch, D, Bodin, D, Brom, Jm, Cardaci, M, Chabert, Ec, Collard, C, Conte, E, Drouhin, F, Ferro, C, Fontaine, Jc, Gele, D, Goerlach, U, Greder, S, Juillot, P, Karim, M, Le Bihan AC, Van Hove, P, Fassi, F, Mercier, D, Baty, C, Beauceron, S, Beaupere, N, Bedjidian, M, Bondu, O, Boudoul, G, Boumediene, D, Brun, H, Chasserat, J, Chierici, R, Contardo, D, Depasse, P, El Mamouni, H, Falkiewicz, A, Fay, J, Gascon, S, Gouzevitch, M, Ille, B, Kurca, T, Le Grand, T, Lethuillier, M, Mirabito, L, Perries, S, Sordini, V, Tosi, S, Tschudi, Y, Verdier, P, Viret, S, Lomidze, D, Anagnostou, G, Beranek, S, Edelhoff, M, Feld, L, Heracleous, N, Hindrichs, O, Jussen, R, Klein, K, Merz, J, Ostapchuk, A, Perieanu, A, Raupach, F, Sammet, J, Schael, S, Sprenger, D, Weber, H, Wittmer, B, Zhukov, V, Ata, M, Caudron, J, Dietz Laursonn, E, Erdmann, M, Guth, A, Hebbeker, T, Heidemann, C, Hoepfner, K, Klimkovich, T, Klingebiel, D, Kreuzer, P, Lanske, D, Lingemann, J, Magass, C, Merschmeyer, M, Meyer, A, Olschewski, M, Papacz, P, Pieta, H, Reithler, H, Schmitz, Sa, Sonnenschein, L, Steggemann, J, Teyssier, D, Weber, M, Bontenackels, M, Cherepanov, V, Davids, M, Flugge, G, Geenen, H, Geisler, M, Ahmad, Wh, Hoehle, F, Kargoll, B, Kress, T, Kuessel, Y, Linn, A, Nowack, A, Perchalla, L, Pooth, O, Rennefeld, J, Sauerland, P, Stahl, A, Zoeller, Mh, Martin, Ma, Behrenhoff, W, Behrens, U, Bergholz, M, Bethani, A, Borras, K, Cakir, A, Campbell, A, Castro, E, Dammann, D, Eckerlin, G, Eckstein, D, Flossdorf, A, Flucke, G, Geiser, A, Hauk, J, Jung, H, Kasemann, M, Katsas, P, Kleinwort, C, Kluge, H, Knutsson, A, Kramer, M, Krucker, D, Kuznetsova, E, Lange, W, Lohmann, W, Lutz, B, Mankel, R, Marfin, I, Marienfeld, M, Melzer Pellmann IA, Meyer, Ab, Mnich, J, Mussgiller, A, Naumann Emme, S, Olzem, J, Petrukhin, A, Pitzl, D, Raspereza, A, Cipriano, Pmr, Rosin, M, Salfeld Nebgen, J, Schmidt, R, Schoerner Sadenius, T, Sen, N, Spiridonov, A, Stein, M, Tomaszewska, J, Walsh, R, Wissing, C, Autermann, C, Blobel, V, Bobrovskyi, S, Draeger, J, Enderle, H, Erfle, J, Gebbert, U, Gorner, M, Hermanns, T, Kaschube, K, Kaussen, G, Kirschenmann, H, Klanner, R, Lange, J, Mura, B, and Nowak, F.
- Subjects
Hadron-Hadron scattering ,Nuclear and High Energy Physics ,CMS experiment ,LHC ,High Energy Physics::Experiment ,Nuclear Experiment - Published
- 2012
20. Shape, transverse size, and charged hadron multiplicity of jets in pp collisions at 7 TeV
- Author
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Chatrchyan, S., Khachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Bergauer, T., Dragicevic, M., Erö, J., Fabjan, C., Friedl, M., Frühwirth, R., Ghete, V. M., Hammer, J., Hoch, M., Hörmann, N., Hrubec, J., Jeitler, M., Kiesenhofer, W., Krammer, M., Liko, D., Mikulec, I., Pernicka, M., Rahbaran, B., Rohringer, C., Rohringer, H., Schöfbeck, R., Strauss, J., Taurok, A., Teischinger, F., Wagner, P., Waltenberger, W., Walzel, G., Widl, E., Wulz, C. E., Mossolov, V., Shumeiko, N., Suarez, Gonzalez, Bansal, J., Benucci, S., Wolf, De, E. A., Janssen, Luyckx, X., Maes, S., Mucibello, T., Ochesanu, L., Roland, S., Rougny, B., Selvaggi, R., Van, Haevermaet, Van, Mechelen, Van, Remortel, Van, Spilbeeck, Blekman, A., Blyweert, F., D'Hondt, S., Gonzalez, Suarez, Kalogeropoulos, R., Maes, A., Olbrechts, M., Van, Doninck, Van, Mulders, Van, Onsem, G. P., Villella, Charaf, I., Clerbaux, O., Lentdecker, De, Dero, G., Gay, V., A. P. R., Hammad, G. H., Hreus, Léonard, T., Marage, A., P. E., Thomas, Vander, Velde, Vanlaer, C., Wickens, P., Adler, J., Beernaert, V., Cimmino, K., Costantini, A., Grunewald, S., Klein, M., Lellouch, B., Marinov, J., Mccartin, A., Ryckbosch, J., Strobbe, D., Thyssen, N., Tytgat, F., Vanelderen, M., Verwilligen, L., Walsh, P., Zaganidis, S., Basegmez, N., Bruno, S., Caudron, G., Ceard, J., De Favereau De Jeneret, Delaere, J., Favart, C., Forthomme, D., Giammanco, L., Grégoire, A., Hollar, G., Lemaitre, J., Liao, V., Militaru, J., Nuttens, O., Pagano, C., Pin, D., Piotrzkowski, A., Schul, K., Beliy, N., Caebergs, N., Daubie, T., Alves, E., G. A., De Jesus Damiao, Pol, D., M. E., Souza, M. H. G., Aldá, J. r., W. L., Carvalho, Custódio, W., Costa, Da, E. M., De Oliveira Martins, Fonseca De Souza, Matos, Figueiredo, Mundim, D., Nogima, L., Oguri, H., Prado Da Silva, W. L., Santoro, Silva Do Amaral, S. M., Sznajder, Anjos, A., T. S., Bernardes, C. A., Dias, F. A., Fernandez Perez Tomei, T. R., Gregores, M., Lagana, E., Marinho, C., Mercadante, F., P. G., Novaes, S. F., Padula, S. S., Darmenov, Genchev, N., Iaydjiev, V., Piperov, P., Rodozov, S., Stoykova, M., Sultanov, S., Tcholakov, G., Trayanov, V., Vutova, R., Dimitrov, M., Hadjiiska, A., Karadzhinova, R., Kozhuharov, A., Litov, V., Pavlov, L., Petkov, B., Bian, P., J. G., Chen, G. M., Chen, H. S., Jiang, C. H., Liang, Liang, D., Meng, S., Tao, X., Wang, J., Wang, X., Xiao, Z., Xu, H., Zang, M., Zhang, J., Ban, Z., Guo, Y., Guo, S., Li, Y., Mao, W., Qian, Y., S. J., Teng, Wang, H., Zhu, S., Zou, B., Cabrera, W., Gomez, Moreno, Ocampo, Rios, A. A., Osorio, Oliveros, A. F., Sanabria, J. C., Godinovic, Lelas, N., Plestina, D., Polic, R., Puljak, D., Antunovic, I., Dzelalija, Z., Kovac, M., Brigljevic, M., Duric, V., Kadija, S., Luetic, K., Morovic, J., Attikis, S., Galanti, A., Mousa, M., Nicolaou, J., Ptochos, C., Razis, F., P. A., Finger, Finger, J. r., Assran, M., Ellithi, Kamel, Khalil, A., Mahmoud, S., M. A., Radi, Hektor, A., Kadastik, A., Müntel, M., Raidal, M., Rebane, M., Tiko, L., Azzolini, A., Eerola, V., Fedi, P., Voutilainen, G., Czellar, M., Härkönen, S., Heikkinen, J., Karimäki, A., Kinnunen, V., Kortelainen, R., M. J., Lampén, Lassila, Perini, Lehti, K., Lindén, S., Luukka, T., Mäenpää, P., Tuominen, T., Tuominiemi, E., Tuovinen, J., Ungaro, E., Wendland, D., Banzuzi, L., Karjalainen, K., Korpela, A., Tuuva, A., Sillou, T., Besancon, D., Choudhury, M., Dejardin, S., Denegri, M., Fabbro, D., Faure, B., J. L., Ferri, Ganjour, F., Givernaud, S., Gras, A., Hamel De Monchenault, Jarry, G., Locci, P., Malcles, E., Marionneau, J., Millischer, M., Rander, L., Rosowsky, J., Shreyber, A., Titov, I., Baffoni, M., Beaudette, S., Benhabib, F., Bianchini, L., Bluj, L., Broutin, M., Busson, C., Charlot, P., Daci, C., Dahms, N., Dobrzynski, T., Elgammal, L., Granier De Cassagnac, Haguenauer, R., Miné, M., Mironov, P., Ochando, C., Paganini, C., Sabes, P., Salerno, D., Sirois, R., Thiebaux, Y., Veelken, C., Zabi, C., Agram, A., J. L., Andrea, Bloch, J., Bodin, D., Brom, D., J. M., Cardaci, Chabert, M., E. C., Collard, Conte, C., Drouhin, E., Ferro, F., Fontaine, C., J. C., Gelé, Goerlach, D., Greder, U., Juillot, S., Karim, P., Bihan, Le, A. C., Van, Hove, Fassi, P., Mercier, F., Baty, D., Beauceron, C., Beaupere, S., Bedjidian, N., Bondu, M., Boudoul, O., Boumediene, G., Brun, D., Chasserat, H., Chierici, J., Contardo, R., Depasse, D., Mamouni, El, Falkiewicz, H., Fay, A., Gascon, J., Ille, S., Kurca, B., Grand, Le, Lethuillier, T., Mirabito, M., Perries, L., Sordini, S., Tosi, V., Tschudi, S., Verdier, Y., Viret, P., Lomidze, S., Anagnostou, D., Beranek, G., Edelhoff, S., Feld, M., Heracleous, L., Hindrichs, N., Jussen, O., Klein, R., Merz, K., Ostapchuk, J., Perieanu, A., Raupach, A., Sammet, F., Schael, J., Sprenger, S., Weber, D., Weber, H., Wittmer, M., Zhukov, B., Ata, V., Dietz, Laursonn, Erdmann, E., Hebbeker, M., Heidemann, T., Hinzmann, C., Hoepfner, A., Klimkovich, K., Klingebiel, T., Kreuzer, D., Lanske, P., Lingemann, D., Magass, J., Merschmeyer, C., Meyer, M., Papacz, A., Pieta, P., Reithler, H., Schmitz, H., S. A., Sonnenschein, Steggemann, L., Teyssier, J., Bontenackels, D., Cherepanov, M., Davids, V., Flügge, M., Geenen, G., Haj, Ahmad, Hoehle, W., Kargoll, F., Kress, B., Kuessel, T., Linn, Y., Nowack, A., Perchalla, A., Pooth, L., Rennefeld, O., Sauerland, J., Stahl, P., Tornier, A., Zoeller, D., M. H., Aldaya, Martin, Behrenhoff, M., Behrens, W., Bergholz, U., Bethani, M., Borras, A., Cakir, K., Campbell, A., Castro, A., Dammann, E., Eckerlin, D., Eckstein, G., Flossdorf, D., Flucke, A., Geiser, G., Hauk, A., Jung, J., Kasemann, H., Katsas, M., Kleinwort, P., Kluge, C., Knutsson, H., Krämer, A., Krücker, M., Kuznetsova, D., Lange, E., Lohmann, W., Lutz, W., Mankel, B., Marfin, R., Marienfeld, I., Melzer, Pellmann, I. A., Meyer, A. B., Mnich, Mussgiller, J., Naumann, Emme, Olzem, S., Petrukhin, J., Pitzl, A., Raspereza, D., Rosin, A., Salfeld, Nebgen, Schmidt, J., Schoerner, Sadenius, Sen, T., Spiridonov, N., Stein, A., Tomaszewska, M., Walsh, J., Wissing, R., Autermann, C., Blobel, C., Bobrovskyi, V., Draeger, S., Enderle, J., Gebbert, H., Görner, U., Hermanns, M., Kaschube, T., Kaussen, K., Kirschenmann, G., Klanner, H., Lange, R., Mura, J., Nowak, B., Pietsch, F., Sander, N., Schettler, C., Schleper, H., Schlieckau, P., Schröder, E., Schum, M., Stadie, T., Steinbrück, H., Thomsen, G., Barth, J., Berger, C., Chwalek, J., Boer, De, Dierlamm, W., Dirkes, A., Feindt, G., Gruschke, M., Guthoff, J., Hackstein, M., Hartmann, C., Heinrich, F., Held, M., Hoffmann, H., K. H., Honc, Katkov, S., Komaragiri, I., J. R., Kuhr, Martschei, T., Mueller, D., Müller, S., T. h., Niegel, Oberst, M., Oehler, O., Ott, A., Peiffer, J., Quast, T., Rabbertz, G., Ratnikov, K., Ratnikova, F., Renz, N., Röcker, M., Saout, S., Scheurer, C., Schieferdecker, A., Schilling, P., F. P., Schmanau, Schott, M., Simonis, G., H. J., Stober, F. M., Troendle, Wagner, Kuhr, Weiler, J., Zeise, T., Ziebarth, M., E. B., Daskalakis, Geralis, G., Kesisoglou, T., Kyriakis, S., Loukas, A., Manolakos, D., Markou, I., Markou, A., Mavrommatis, C., Ntomari, C., Petrakou, E., Gouskos, E., Mertzimekis, L., T. J., Panagiotou, Saoulidou, A., Stiliaris, N., Evangelou, E., Foudas, I., Kokkas, C., Manthos, P., Papadopoulos, N., Patras, I., Triantis, V., F. A., Aranyi, Bencze, A., Boldizsar, G., Hajdu, L., Hidas, C., Horvath, P., Kapusi, D., Krajczar, A., Sikler, K., Veres, F., G. I., Vesztergomb, Beni, G., Molnar, N., Palinkas, J., Szillasi, J., Veszpremi, Z., Karancsi, V., Raics, J., Trocsanyi, P., Z. L., Ujvari, Beri, B., S. B., Bhatnagar, Dhingra, V., Gupta, N., Jindal, R., Kaur, M., Kohli, M., J. M., Mehta, M. Z., Nishu, Saini, N., L. K., Sharma, Singh, A., A. P., Singh, Singh, J., S. P., Ahuja, Choudhary, S., B. C., Kumar, Kumar, A., Malhotra, A., Naimuddin, S., Ranjan, M., Shivpuri, K., R. K., Banerjee, Bhattacharya, S., Dutta, S., Gomber, S., Jain, B., S. a., Jain, S. h., Khurana, Sarkar, R., Choudhury, S., R. K., Dutta, Kailas, D., Kumar, S., Mohanty, V., A. K., Pant, L. M., Shukla, Aziz, P., Guchait, T., Gurtu, M., Maity, A., Majumder, M., Majumder, D., Mazumdar, G., Mohanty, K., G. B., Parida, Saha, B., Sudhakar, A., Wickramage, K., Banerjee, N., Dugad, S., Mondal, S., N. K., Arfaei, Bakhshiansohi, H., Etesami, H., S. M., Fahim, Hashemi, A., Hesari, M., Jafari, H., Khakzad, A., Mohammadi, M., Mohammadi, Najafabadi, Paktinat, Mehdiabadi, Safarzadeh, S., Zeinali, B., Abbrescia, M., Barbone, M., Calabria, L., Colaleo, C., Creanza, A., Filippis, De, Palma, De, Fiore, M., Iaselli, L., Lusito, G., Maggi, L., Maggi, G., Manna, M., Marangelli, N., My, B., Nuzzo, S., Pacifico, S., Pompili, N., Pugliese, A., Romano, G., Selvaggi, F., Silvestris, G., Tupputi, L., Zito, S., Abbiendi, G., Benvenuti, G., A. C., Bonacorsi, Braibant, Giacomelli, Brigliadori, S., Capiluppi, L., Castro, P., Cavallo, A., F. R., Cuffani, Dallavalle, M., G. M., Fabbri, Fanfani, F., Fasanella, A., Giacomelli, D., Grandi, P., Marcellini, C., Masetti, S., Meneghelli, G., Montanari, M., Navarria, A., F. L., Odorici, Perrotta, F., Primavera, A., Rossi, F., A. M., Rovelli, Siroli, T., Travaglini, G., Albergo, R., Cappello, S., Chiorboli, G., Costa, M., Potenza, S., Tricomi, R., Tuve, A., Barbagli, C., Ciulli, G., Civinini, V., D'Alessandro, C., Focardi, R., Frosali, E., Gallo, S., Gonzi, E., Meschini, S., Paoletti, M., Sguazzoni, S., Tropiano, G., Benussi, A., Bianco, L., Colafranceschi, S., Fabbri, S., Piccolo, F., Fabbricatore, D., Musenich, P., Benaglia, R., Guio, De, Matteo, Di, Gennai, L., Ghezzi, S., Malvezzi, A., Martelli, S., Massironi, A., Menasce, A., Moroni, D., Paganoni, L., Pedrini, M., Ragazzi, D., Redaelli, S., Sala, N., Tabarelli De Fatis, Buontempo, T., Carrillo, Montoya, C. A., Cavallo, Cosa, De, Dogangun, A., Fabozzi, O., Iorio, F., A. O. M., Lista, Merola, L., Paolucci, M., Azzi, P., Bacchetta, P., Bellan, N., Bisello, P., Branca, D., Carlin, A., Checchia, R., Dorigo, P., Dosselli, T., Gasparini, U., Gasparini, F., Gozzelino, U., Gulmini, A., Lacaprara, M., Lazzizzera, S., Margoni, I., Meneguzzo, M., A. 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P., Contreras, Campana, Duggan, E., Ferencek, D., Gershtein, D., Gray, Y., Halkiadakis, R., Hidas, E., Hits, D., Lath, D., Panwalkar, A., Park, S., Patel, M., Richards, R., Rose, A., Salur, K., Schnetzer, S., Somalwar, S., Stone, S., Thomas, R., Cerizza, S., Hollingsworth, G., Spanier, M., Z. C., York, Eusebi, A., Flanagan, R., Gilmore, W., Kamon, J., Khotilovich, T., Montalvo, V., Osipenkov, R., Pakhotin, I., Perloff, Y., Roe, A., Safonov, J., Sengupta, A., Suarez, S., Tatarinov, I., Toback, A., Akchurin, D., Bardak, N., Damgov, C., Dudero, J., P. R., Jeong, Kovitanggoon, C., Lee, K., S. W., Libeiro, Mane, T., Roh, P., Sill, Y., Volobouev, A., Wigmans, I., Yazgan, R., Appelt, E., Brownson, E., Engh, E., Florez, D., Gabella, C., Gurrola, W., Issah, A., Johns, M., Johnston, W., Kurt, C., Maguire, P., Melo, C., Sheldon, A., Snook, P., Tuo, B., Velkovska, S., Arenton, J., M. W., Balazs, Boutle, M., Conetti, S., Cox, S., Francis, B., Goadhouse, B., Goodell, S., Hirosky, J., Ledovskoy, R., Lin, A., Neu, C., Wood, C., Yohay, J., Gollapinni, R., Harr, S., Karchin, R., P. E., Kottachchi Kankanamge Don, Lamichhane, C., Mattson, P., Milstène, M., Sakharov, C., Anderson, A., Bachtis, M., Belknap, M., Bellinger, D., J. N., Bernardini, Carlsmith, J., Cepeda, D., Dasu, M., Efron, S., Friis, J., Gray, E., Grogg, L., K. S., Grothe, Hall, Wilton, Herndon, R., Hervé, A., Klabbers, P., Klukas, J., Lanaro, A., Lazaridis, C., Leonard, J., Loveless, R., Mohapatra, A., Ojalvo, I., Pierro, G. A., Ross, I., Savin, A., Smith, W. H., Swanson, J., Weinberg, eiden A, M., Seifert, F, Seixas, Jm, Sekhniaidze, G, Seliverstov, Dm, Sellden, B, Sellers, G, Seman, M, Semprini Cesari, N, Serfon, C, Serin, L, Seuster, R, Severini, H, Sevior, Me, Sfyrla, A, Shabalina, E, Shamim, M, Shan, Ly, Shank, Jt, Shao, Qt, Shapiro, M, Shatalov, Pb, Shaver, L, Shaw, K, Sherman, D, Sherwood, P, Shibata, A, Shichi, H, Shimizu, S, Shimojima, M, Shin, T, Shiyakova, M, Shmeleva, A, Shochet, Mj, Short, D, Shrestha, S, Shupe, Ma, Sicho, P, Sidoti, A, Siebel, A, Siegert, F, Sijacki, D, Silbert, O, Silva, J, Silver, Y, Silverstein, D, Silverstein, Sb, Simak, V, Simard, O, Simic, L, Simion, S, Simmons, B, Simonyan, M, Sinervo, P, Sinev, Nb, Sipica, V, Siragusa, G, Sircar, A, Sisakyan, An, Sivoklokov, Sy, Sjolin, J, Sjursen, Tb, Skinnari, La, Skottowe, Hp, Skovpen, K, Skubic, P, Skvorodnev, N, Slater, M, Slavicek, T, Sliwa, K, Sloper, J, Smakhtin, V, Smirnov, Sy, Smirnova, Ln, Smirnova, O, Smith, Bc, Smith, D, Smith, Km, Smizanska, M, Smolek, K, 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I, Stupak, J, Sturm, P, Soh, Da, Su, D, Subramania, Hs, Succurro, A, Sugaya, Y, Sugimoto, T, Suhr, C, Suita, K, Suk, M, Sulin, Vv, Sultansoy, S, Sumida, T, Sun, X, Sundermann, Je, Suruliz, K, Sushkov, S, Susinno, G, Sutton, Mr, Suzuki, Y, Svatos, M, Sviridov, Ym, Swedish, S, Sykora, I, Sykora, T, Szeless, B, Sanchez, J, Ta, D, Tackmann, K, Taffard, A, Tafirout, R, Taiblum, N, Takahashi, Y, Takai, H, Takashima, R, Takeda, H, Takeshita, T, Talby, M, Talyshev, A, Tamsett, Mc, Tanaka, J, Tanaka, R, Tanaka, S, Tanaka, Y, Tani, K, Tannoury, N, Tappern, Gp, Tapprogge, S, Tardif, D, Tarem, S, Tarrade, F, Tartarelli, Gf, Tas, P, Tasevsky, M, Tassi, E, Tatarkhanov, M, Tayalati, Y, Taylor, C, Taylor, Fe, Taylor, Gn, Taylor, W, Teinturier, M, Castanheira, Mtd, Teixeira Dias, P, Temming, Kk, Ten Kate, H, Teng, Pk, Terada, S, Terashi, K, Terron, J, Terwort, M, Testa, M, Teuscher, Rj, Thadome, J, Therhaag, J, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire Leprince-Ringuet (LLR), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Département Recherches Subatomiques (DRS-IPHC), Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), CMS, Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), UAM. Departamento de Física Teórica, V. KHACHATRYAN, A.M. SIRUNYAN, A. TUMASYAN, W. ADAM, T. BERGAUER, M. DRAGICEVIC, J. ER¨O, C. FABJAN, M. FRIEDL, R. FRUHWIRTH, V.M. GHETE, J. HAMMER, S. H¨ANSEL, C. HARTL, M. HOCH, N. H N(ORMANN, J. HRUBEC, M. JEITLER, G. KASIECZKA, W. KIESENHOFER, M. KRAMMER, D. LIKO, I. MIKULEC, M. PERNICKA, H. ROHRINGER, R. SCH N(OFBECK, J. STRAUSS, A. TAUROK, F. TEISCHINGER, W.WALTENBERGER, G.WALZEL, E.WIDL, C.-E.WULZ, V. MOSSOLOV, N. SHUMEIKO, J. SUAREZ GONZALEZ, L. BENUCCI, L. CEARD, E.A. DE WOLF, X. JANSSEN, T. MAES, L. MUCIBELLO, S. OCHESANU, B. ROLAND, R. ROUGNY, M. SELVAGGI, H. VAN HAEVERMAET, P. VAN MECHELEN, N. VAN REMORTEL, V. ADLER, S. BEAUCERON, S. BLYWEERT, J. D $B!G (BHONDT, O. DEVROEDE, A. KALOGEROPOULOS, J. MAES, M. MAES, S. TAVERNIER, W. VAN DONINCK, P. VAN MULDERS, I. VILLELLA, E.C. CHABERT, O. CHARAF, B. CLERBAUX, G. DE LENTDECKER, V. DERO, A.P.R. GAY, G.H. HAMMAD, T. HREUS, P.E. MARAGE, C. VANDER VELDE, P. VANLAER, J.WICKENS, S. COSTANTINI, M. GRUNEWALD, B. KLEIN, A. MARINOV, D. RYCKBOSCH, F. THYSSEN, M. TYTGAT, L. VANELDEREN, P. VERWILLIGEN, S.WALSH, N. ZAGANIDIS, S. BASEGMEZ, G. BRUNO, J. CAUDRON, J. DE FAVEREAU DE JENERET, C. DELAERE, P. DEMIN, D. FAVART, A. GIAMMANCO, G. GR N4EGOIRE, J. HOLLAR, V. LEMAITRE, O. MILITARU, S. OVYN, D. PAGANO, A. PIN, K. PIOTRZKOWSKI, L. QUERTENMONT, N. SCHUL, N. BELIY, T. CAEBERGS, E. DAUBIE, G.A. ALVES, D. DE JESUS DAMIAO, M.E. POL, M.H.G. SOUZA, W. CARVALHO, E.M. DA COSTA, C. DE OLIVEIRA MARTINS, S. FONSECA DE SOUZA, L. MUNDIM, H. NOGIMA, V. OGURI, J.M. OTALORA GOICOCHEA, W.L. PRADO DA SILVA, A. SANTORO, S.M. SILVA DO, AMARAL, A. SZNAJDER, F. TORRES DA SILVA DE ARAUJO, F.A. DIAS, M.A.F. DIAS, T.R. FERNANDEZ PEREZ TOMEI, E. M. GREGORES2, F. MARINHO, S.F. NOVAES, SANDRA S. PADULA, N. DARMENOV, L. DIMITROV, V. GENCHEV, P. IAYDJIEV, S. PIPEROV, M. RODOZOV, S. STOYKOVA, G. SULTANOV, V. TCHOLAKOV, R. TRAYANOV, I. VANKOV, M. DYULENDAROVA, R. HADJIISKA, V. KOZHUHAROV, L. LITOV, E. MARINOVA, M. MATEEV, B. PAVLOV, P. PETKOV, J.G. BIAN, G.M. CHEN, H.S. CHEN, C.H. JIANG, D. LIANG, S. LIANG, J. WANG, X. WANG, Z.WANG, M. YANG, J. ZANG, Z. ZHANG, Y. BAN, S. GUO, Z. HU, W. LI, Y. MAO, S.J. QIAN, H. TENG, B. ZHU, A. CABRERA, B. GOMEZ MORENO, A.A. OCAMPO RIOS, A.F. OSORIO OLIVEROS, J.C. SANABRIA, N. GODINOVIC, D. LELAS, K. LELAS, R. PLESTINA3, D. POLIC, I. PULJAK, Z. ANTUNOVIC, M. DZELALIJA, V. BRIGLJEVIC, S. DURIC, K. KADIJA, S. MOROVIC, A. ATTIKIS, R. FEREOS, M. GALANTI, J. MOUSA, C. NICOLAOU, F. PTOCHOS, P.A. RAZIS, H. RYKACZEWSKI, Y. ASSRAN, M.A. MAHMOUD, A. HEKTOR, M. KADASTIK, K. KANNIKE, M. M N(UNTEL, M. RAIDAL, L. REBANE, V. AZZOLINI, P. EEROLA, S. CZELLAR, J. H N(ARK N(ONEN, A. HEIKKINEN, V. KARIM N(AKI, R. KINNUNEN, J. KLEM, M.J. KORTELAINEN, T. LAMP N4EN, K. LASSILA-PERINI, S. LEHTI, T. LIND N4EN, P. LUUKKA, T. M N(AENP N(A N(A, E. TUOMINEN, J. TUOMINIEMI, E. TUOVINEN, D. UNGARO, L.WENDLAND, K. BANZUZI, A. KORPELA, T. TUUVA, D. SILLOU, M. BESANCON, M. DEJARDIN, D. DENEGRI, J. DESCAMPS, B. FABBRO, J.L. FAURE, F. FERRI, S. GANJOUR, F.X. GENTIT, A. GIVERNAUD, P. GRAS, G. HAMEL DE MONCHENAULT, P. JARRY, E. LOCCI, J. MALCLES, M. MARIONNEAU, L. MILLISCHER, J. RANDER, A. ROSOWSKY, D. ROUSSEAU, M. TITOV, P. VERRECCHIA, S. BAFFIONI, L. BIANCHINI, M. BLUJ, C. BROUTIN, P. BUSSON, C. CHARLOT, L. DOBRZYNSKI, R. GRANIER DE, CASSAGNAC, M. HAGUENAUER, P. MIN N4E, C. MIRONOV, C. OCHANDO, P. PAGANINI, D. SABES, R. SALERNO, Y. SIROIS, C. THIEBAUX, A. ZABI, J.-L. AGRAM, A. BESSON, D. BLOCH, D. BODIN, J.-M. BROM, M. CARDACI, E. CONTE, F. DROUHIN, C. FERRO, J.-C. FONTAINE, D. GEL N4E, U. GOERLACH, S. GREDER, P. JUILLOT, M. KARIM, A.-C. LE BIHAN, Y. MIKAMI, P. VAN HOVE, F. FASSI, D. MERCIER, C. BATY, N. BEAUPERE, M. BEDJIDIAN, O. BONDU, G. BOUDOUL, D. BOUMEDIENE, H. BRUN, N. CHANON, R. CHIERICI, D. CONTARDO, P. DEPASSE, H. EL MAMOUNI, A. FALKIEWICZ, J. FAY, S. GASCON, B. ILLE, T. KURCA, T. LE GRAND, M. LETHUILLIER, L. MIRABITO, S. PERRIES, V. SORDINI, S. TOSI, Y. TSCHUDI, P. VERDIER, H. XIAO, V. ROINISHVILI, G. ANAGNOSTOU, M. EDELHOFF, L. FELD, N. HERACLEOUS, O. HINDRICHS, R. JUSSEN, K. KLEIN, J. MERZ, N. MOHR, A. OSTAPCHUK, A. PERIEANU, F. RAUPACH, J. SAMMET, S. SCHAEL, D. SPRENGER, H. WEBER, M.WEBER, B.WITTMER, M. ATA, W. BENDER, M. ERDMANN, J. FRANGENHEIM, T. HEBBEKER, A. HINZMANN, K. HOEPFNER, C. HOF, T. KLIMKOVICH, D. KLINGEBIEL, P. KREUZER1, D. LANSKEY, C. MAGASS, M. MERSCHMEYER, A. MEYER, P. PAPACZ, H. PIETA, H. REITHLER, S.A. SCHMITZ, L. SONNENSCHEIN, J. STEGGEMANN, D. TEYSSIER, M. BONTENACKELS, M. DAVIDS, M. DUDA, G. FL N(UGGE, H. GEENEN, M. GIFFELS, W. HAJ AHMAD, D. HEYDHAUSEN, T. KRESS, Y. KUESSEL, A. LINN, A. NOWACK, L. PERCHALLA, O. POOTH, J. RENNEFELD, P. SAUERLAND, A. STAHL, M. THOMAS, D. TORNIER, M.H. ZOELLER, M. ALDAYA MARTIN, W. BEHRENHOFF, U. BEHRENS, M. BERGHOLZ, K. BORRAS, A. CAMPBELL, E. CASTRO, D. DAMMANN, G. ECKERLIN, A. FLOSSDORF, G. FLUCKE, A. GEISER, I. GLUSHKOV, J. HAUK, H. JUNG, M. KASEMANN, I. KATKOV, P. KATSAS, C. KLEINWORT, H. KLUGE, A. KNUTSSON, D. KR N( UCKER, E. KUZNETSOVA, W. LANGE, W. LOHMANN, R. MANKEL, M. MARIENFELD, I.-A. MELZER-PELLMANN, A.B. MEYER, J. MNICH, A. MUSSGILLER, J. OLZEM, A. PARENTI, A. RASPEREZA, A. RAVAL, R. SCHMIDT, T. SCHOERNER-SADENIUS, N. SEN, M. STEIN, J. TOMASZEWSKA, D. VOLYANSKYY, R.WALSH, C.WISSING, C. AUTERMANN, S. BOBROVSKYI, J. DRAEGER, D. ECKSTEIN, H. ENDERLE, U. GEBBERT, K. KASCHUBE, G. KAUSSEN, R. KLANNER, B. MURA, S. NAUMANN-EMME, F. NOWAK, N. PIETSCH, C. SANDER, H. SCHETTLER, P. SCHLEPER, M. SCHR N(ODER, T. SCHUM, J. SCHWANDT, A.K. SRIVASTAVA, H. STADIE, G. STEINBR N(UCK, J. THOMSEN, R.WOLF, J. BAUER, V. BUEGE, A. CAKIR, T. CHWALEK, D. DAEUWEL, W. DE BOER, A. DIERLAMM, G. DIRKES, M. FEINDT, J. GRUSCHKE, C. HACKSTEIN, F. HARTMANN, M. HEINRICH, H. HELD, K.H. HOFFMANN, S. HONC, T. KUHR, D. MARTSCHEI, S. MUELLER, TH. M N(ULLER, M.B. NEULAND, M. NIEGEL, O. OBERST, A. OEHLER, J. OTT, T. PEIFFER, D. PIPARO, G. QUAST, K. RABBERTZ, F. RATNIKOV, M. 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DEMIR, C. DOZEN, I. DUMANOGLU, E. ESKUT, S. GIRGIS, G. G N(OKBULUT, Y. G N( ULER, E. GURPINAR, I. HOS, E.E. KANGAL, T. KARAMAN, A. KAYIS TOPAKSU, A. NART, G. O N( NENGU N( T, K. OZDEMIR, S. OZTURK, A. POLATO N(Z, K. SOGUT, B. TALI, H. TOPAKLI, D. UZUN, L.N. VERGILI, M. VERGILI, C. ZORBILMEZ, I.V. AKIN, T. ALIEV, S. BILMIS, M. DENIZ, H. GAMSIZKAN, A.M. GULER, K. OCALAN, A. OZPINECI, M. SERIN, R. SEVER, U.E. SURAT, E. YILDIRIM, M. ZEYREK, M. DELIOMEROGLU, D. DEMIR, E. GU¨LMEZ, A. HALU, B. ISILDAK, M. KAYA, O. KAYA, M. O¨ZBEK, S. OZKORUCUKLU, N. SONMEZ, L. LEVCHUK, P. BELL, F. BOSTOCK, J.J. BROOKE, T.L. CHENG, D. CUSSANS, R. FRAZIER, J. GOLDSTEIN, M. GRIMES, G.P. HEATH, H.F. HEATH, C. HILL, B. HUCKVALE, J. JACKSON, L. KRECZKO, S. METSON, D.M. NEWBOLD, K. NIRUNPONG, A. POLL, V.J. SMITH, S.WARD, L. BASSO, K.W. BELL, A. BELYAEV, C. BREW, R.M. BROWN, B. CAMANZI, D.J.A. COCKERILL, J.A. COUGHLAN, K. HARDER, S. HARPER, B.W. KENNEDY, E. OLAIYA, D. PETYT, B.C. RADBURN-SMITH, C.H. SHEPHERD-THEMISTOCLEOUS, I.R. TOMALIN, W.J.WOMERSLEY, S.D.WORM, R. BAINBRIDGE, G. BALL, J. BALLIN, R. BEUSELINCK, O. BUCHMULLER, D. COLLING, N. CRIPPS, M. CUTAJAR, G. DAVIES, M. DELLA NEGRA, C. FOUDAS, J. FULCHER, D. FUTYAN, A. GUNERATNE BRYER, G. HALL, Z. HATHERELL, J. HAYS, G. ILES, G. KARAPOSTOLI, L. LYONS, A.-M. MAGNAN, J. MARROUCHE, R. NANDI, J. NASH, A. NIKITENKO, A. PAPAGEORGIOU, M. PESARESI, K. PETRIDIS, M. PIOPPI, D.M. RAYMOND, N. ROMPOTIS, A. ROSE, M.J. RYAN, C. SEEZ, P. SHARP, A. SPARROW, A. TAPPER, S. TOURNEUR, M. VAZQUEZ ACOSTA, T. VIRDEE1, S.WAKEFIELD, D.WARDROPE, T. WHYNTIE, M. BARRETT, M. CHADWICK, J.E. COLE, P.R. HOBSON, A. KHAN, P. KYBERD, D. LESLIE, W. MARTIN, I.D. REID, L. TEODORESCU, K. HATAKEYAMA, T. BOSE, E. CARRERA JARRIN, A. CLOUGH, C. FANTASIA, A. HEISTER, J. ST. JOHN, P. LAWSON, D. LAZIC, J. ROHLF, L. SULAK, J. ANDREA, A. AVETISYAN, J.P. CHOU, D. CUTTS, S. ESEN, A. FERAPONTOV, U. HEINTZ, S. JABEEN, G. KUKARTSEV, G. LANDSBERG, M. NARAIN, D. NGUYEN, M. SEGALA, T. SPEER, K.V. TSANG, M.A. BORGIA, R. BREEDON, M. CALDERON DE LA BARCA SANCHEZ, D. CEBRA, M. CHERTOK, J. CONWAY, P.T. COX, J. DOLEN, R. ERBACHER, E. FRIIS, W. KO, A. KOPECKY, R. LANDER, H. LIU, S. MARUYAMA, T. MICELI, M. NIKOLIC, D. PELLETT, J. ROBLES, T. SCHWARZ, M. SEARLE, J. SMITH, M. SQUIRES, M. TRIPATHI, R. VASQUEZ SIERRA, C. VEELKEN, K. ARISAKA, D. CLINE, R. COUSINS, A. DEISHER, J. DURIS, S. ERHAN, C. FARRELL, J. HAUSER, M. IGNATENKO, C. JARVIS, C. PLAGER, G. RAKNESS, P. SCHLEIN, J. TUCKER, V. VALUEV, J. BABB, R. CLARE, J. ELLISON, J.W. GARY, F. GIORDANO, G. HANSON, G.Y. JENG, S.C. KAO, F. LIU, A. LUTHRA, H. NGUYEN, G. PASZTOR, A. SATPATHY, B.C. SHENY, R. STRINGER, J. STURDY, S. SUMOWIDAGDO, R.WILKEN, S.WIMPENNY, W. ANDREWS, J.G. BRANSON, E. DUSINBERRE, D. EVANS, F. GOLF, A. HOLZNER, R. KELLEY, M. LEBOURGEOIS, J. LETTS, B. MANGANO, J. MUELMENSTAEDT, S. PADHI, C. PALMER, G. PETRUCCIANI, H. PI, M. PIERI, R. RANIERI, M. SANI, V. SHARMA1, S. SIMON, Y. TU, A. VARTAK, F. W N(URTHWEIN, A. YAGIL, D. BARGE, R. BELLAN, C. CAMPAGNARI, M. D'ALFONSO, T. DANIELSON, P. GEFFERT, J. INCANDELA, C. JUSTUS, P. KALAVASE, S.A. KOAY, D. KOVALSKYI, V. KRUTELYOV, S. LOWETTE, N. MCCOLL, V. PAVLUNIN, F. REBASSOO, J. RIBNIK, J. RICHMAN, R. ROSSIN, D. STUART, W. TO, J.R. VLIMANT, M.WITHERELL, A. BORNHEIM, J. BUNN, Y. CHEN, M. GATAULLIN, D. KCIRA, V. LITVINE, Y. MA, A. MOTT, H.B. NEWMAN, C. ROGAN, K. SHIN, V. TIMCIUC, P. TRACZYK, J. VEVERKA, R.WILKINSON, Y. YANG, R.Y. ZHU, B. AKGUN, A. CALAMBA, R. CARROLL, T. FERGUSON, Y. IIYAMA, D.W. JANG, S.Y. JUN, Y.F. LIU, M. PAULINI, J. RUSS, N. TERENTYEV, H. VOGEL, I. VOROBIEV, J.P. CUMALAT, M.E. DINARDO, B.R. DRELL, C.J. EDELMAIER, W.T. FORD, B. HEYBURN, E. LUIGGI LOPEZ, U. NAUENBERG, J.G. SMITH, K. STENSON, K.A. ULMER, S.R.WAGNER, S.L. ZANG, L. AGOSTINO, J. ALEXANDER, F. BLEKMAN, A. CHATTERJEE, S. DAS, N. EGGERT, L.J. FIELDS, L.K. GIBBONS, B. HELTSLEY, K. HENRIKSSON, W. HOPKINS, A. KHUKHUNAISHVILI, B. KREIS, V. KUZNETSOV, Y. LIU, G. NICOLAS KAUFMAN, J.R. PATTERSON, D. PUIGH, D. RILEY, A. RYD, M. SAELIM, X. SHI, W. SUN, W.D. TEO, J. THOM, J. THOMPSON, J. VAUGHAN, Y.WENG, P.WITTICH, A. BISELLI, G. CIRINO, D. WINN, S. ABDULLIN, M. ALBROW, J. ANDERSON, G. APOLLINARI, M. ATAC, J.A. BAKKEN, L.A.T. BAUERDICK, A. BERETVAS, J. BERRYHILL, P.C. BHAT, I. BLOCH, F. BORCHERDING, K. BURKETT, J.N. BUTLER, V. CHETLURU, H.W.K. CHEUNG, F. CHLEBANA, S. CIHANGIR, M. DEMARTEAU, D.P. EARTLY, V.D. ELVIRA, I. FISK, J. FREEMAN, Y. GAO, E. GOTTSCHALK, D. GREEN, K. GUNTHOTI, O. GUTSCHE, A. HAHN, J. HANLON, R.M. HARRIS, J. HIRSCHAUER, E. JAMES, H. JENSEN, M. JOHNSON, U. JOSHI, R. KHATIWADA, B. KILMINSTER, B. KLIMA, K. KOUSOURIS, S. KUNORI, S. KWAN, P. LIMON, R. LIPTON, J. LYKKEN, K. MAESHIMA, J.M. MARRAFFINO, D. MASON, P. MCBRIDE, T. MCCAULEY, T. MIAO, K. MISHRA, S. MRENNA, Y. MUSIENKO, C. NEWMAN-HOLMES, V. O $B!G (BDELL, S. POPESCU, R. PORDES, O. PROKOFYEV, N. SAOULIDOU, E. SEXTON-KENNEDY, S. SHARMA, A. SOHA, W.J. SPALDING, L. SPIEGEL, P. 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TOBACK, M.WEINBERGER, N. AKCHURIN, C. BARDAK, J. DAMGOV, C. JEONG, K. KOVITANGGOON, S.W. LEE, P. MANE, Y. ROH, A. SILL, I. VOLOBOUEV, R.WIGMANS, E. YAZGAN, E. APPELT, E. BROWNSON, D. ENGH, C. FLOREZ, W. GABELLA, W. JOHNS, P. KURT, C. MAGUIRE, A. MELO, P. SHELDON, J. VELKOVSKA, M.W. ARENTON, M. BALAZS, S. BOUTLE, M. BUEHLER, S. CONETTI, B. COX, B. FRANCIS, R. HIROSKY, A. LEDOVSKOY, C. LIN, C. NEU, T. PATEL, R. YOHAY, S. GOLLAPINNI, R. HARR, P.E. KARCHIN, V. LOGGINS, M. MATTSON, C. MILST`ENE, A. SAKHAROV, M. ANDERSON, M. BACHTIS, J.N. BELLINGER, D. CARLSMITH, S. DASU, J. EFRON, L. GRAY, K.S. GROGG, M. GROTHE, R. HALL-WILTON, M. HERNDON, P. KLABBERS, J. KLUKAS, A. LANARO, C. LAZARIDIS, J. LEONARD, J. LIU, D. LOMIDZE, R. LOVELESS, A. MOHAPATRA, W. PARKER, D. REEDER, I. ROSS, A. SAVIN, W.H. SMITH, J. SWANSON, M.WEINBERG, S.CHATRCHYAN, F. PRIMAVERA, L. 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H, Ecklund, K, Geurts, F, Padley, B, Barbaro, P, Miner, D, Chou, J, Yang, Z, Dudero, P, Arenton, M, Karchin, P, Don, C, Milstène, C, Bellinger, J, Hervé, A, Pierro, G, Smith, W, Weinberg, M, TABARELLI DE FATIS, T, CMS Collaboration, UCL - SST/IRMP - Institut de recherche en mathématique et physique, Universidad de Cantabria, CMS Collaboration (ukupan broj autora: 2261), Belforte, S., Cossutti, F., DELLA RICCA, Giuseppe, Gobbo, B., Marone, Matteo, Montanino, Damiana, Penzo, A., The, CMS Collaboration, Iorio, ALBERTO ORSO MARIA, Others, Merola, Mario, and Çukurova Üniversitesi, Fen-Edebiyat Fakültesi, Fizik Bölümü
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Particle physics ,Nuclear and High Energy Physics ,Astrophysics::High Energy Astrophysical Phenomena ,Monte Carlo method ,Hadron ,HERA ,FOS: Physical sciences ,ComputingMilieux_LEGALASPECTSOFCOMPUTING ,Hadron-hadron scattering ,7. Clean energy ,01 natural sciences ,PARTICLE PHYSICS ,LARGE HADRON COLLIDER ,CMS ,High Energy Physics - Experiment ,Nuclear physics ,DEEP-INELASTIC SCATTERING ,High Energy Physics - Experiment (hep-ex) ,0103 physical sciences ,[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex] ,DISTRIBUTIONS ,ddc:530 ,Multiplicity (chemistry) ,010306 general physics ,Nuclear Experiment ,deep-inelastic scattering ,hadron-hadron scattering ,hera ,distributions ,Quantum chromodynamics ,Physics ,high energy collider ,Large Hadron Collider ,010308 nuclear & particles physics ,Física ,Deep inelastic scattering ,HEP ,Transverse plane ,FIS/01 - FISICA SPERIMENTALE ,Physique des particules élémentaires ,High Energy Physics::Experiment ,LHC ,Particle Physics - Experiment - Abstract
Open Access: This article is distributed under the terms of the Creative Commons Attribution License.-- CMS Collaboration: et al., Measurements of jet characteristics from inclusive jet production in proton-proton collisions at a centre-of-mass energy of 7 TeV are presented. The data sample was collected with the CMS detector at the LHC during 2010 and corresponds to an integrated luminosity of 36 inverse picobarns. The mean charged hadron multiplicity, the differential and integral jet shape distributions, and two independent moments of the shape distributions are measured as functions of the jet transverse momentum for jets reconstructed with the anti-kT algorithm. The measured observables are corrected to the particle level and compared with predictions from various QCD Monte Carlo generators., European Commission; Federal Ministry of Science, Research and Economy (Austria); National Fund for Scientific Research (Belgium); Research Foundation – Flanders; Conselho Nacional de Desenvolvimento Científico e Tecnológico (Brasil); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil); Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Fundação de Amparo à Pesquisa do Estado de São Paulo; Bulgarian Ministry of Education and Science; Centre National de la Recherche Scientifique (France); Commissariat à l'énergie atomique et aux énergies alternatives (France); Ministry of Science and Technology of the People's Republic of China; Chinese Academy of Sciences; National Natural Science Foundation of China; Colciencias (Colombia); Croatian Ministry of Science, Education and Sport; Academy of Finland; Helsinki Institute of Physics; Bundesministerium für Bildung und Forschung (Deutschland); Deutsche Forschungsgemeinschaft; Helmholtz Association; General Secretariat of Research and Technology (Greece); Hungarian Scientific Research Fund; National Office for Research and Technology (Hungary); Department of Atomic Energy (India); Department of Science and Technology (India); Council of Science and Industrial Research (India); Institute for Research in Fundamental Sciences (Iran); Science Foundation Ireland; Istituto Nazionale di Fisica Nucleare (Italia); Korean Ministry of Education, Science and Technology; Lithuanian Academy of Sciences; Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (México); Consejo Nacional de Ciencia y Tecnología (México); Secretaría de Educación Pública (México); Universidad Autónoma de San Luis Potosí; Ministry of Science and Innovation (New Zealand); Ministry of Science and Higher Education and the National Science Centre (Poland); Fundação para a Ciência e a Tecnologia (Portugal); Joint Institute for Nuclear Research (Russia); Russian Academy of Sciences; Russian Foundation for Basic Research; Ministry of Education, Science and Technological Development (Serbia); Ministerio de Ciencia e Innovación (España); Swiss Funding Agencies; Swiss National Science Foundation; National Science Council (Taiwan); The Scientific and Technological Research Council of Turkey; Turkish Atomic Energy Authority; Science and Technology Facilities Council (UK); Department of Energy (US); National Science Foundation (US); A. G. Leventis Foundation; Alfred P. Sloan Foundation; Alexander von Humboldt Foundation; Foundation for Polish Science
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- 2012
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21. Study of W boson production in PbPb and pp collisions at √sNN=2.76 TeV
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Chatrchyan, S., Khachatryan, V., Sirunyan, A. M., Tumasyan, A., Adam, W., Bergauer, T., Dragicevic, M., Erö, J., Fabjan, C., Friedl, M., Frühwirth, R., Ghete, V. M., Hammer, J., Hörmann, N., Hrubec, J., Jeitler, M., Kiesenhofer, W., Knünz, V., Krammer, M., Liko, D., Mikulec, I., Pernicka, M., Rahbaran, B., Rohringer, C., Rohringer, H., Schöfbeck, R., Strauss, J., Taurok, A., Wagner, P., Waltenberger, W., Walzel, G., Widl, E., Wulz, C. E., Mossolov, V., Shumeiko, N., Suarez, Gonzalez, Bansal, J., Cornelis, S., Wolf, De, E. A., Janssen, Luyckx, X., Maes, S., Mucibello, T., Ochesanu, L., Roland, S., Rougny, B., Selvaggi, R., Staykova, M., Van, Haevermaet, Van, Mechelen, Van, Remortel, Van, Spilbeeck, Blekman, A., Blyweert, F., D'Hondt, S., Gonzalez, Suarez, Kalogeropoulos, R., Maes, A., Olbrechts, M., Van, Doninck, Van, Mulders, Van, Onsem, G. P., Villella, Charaf, I., Clerbaux, O., Lentdecker, De, Dero, G., Gay, V., A. P. R., Hreus, Léonard, T., Marage, A., P. 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P., Redjimi, Roberts, R., Zabel, J., Betchart, J., Bodek, B., Chung, A., Y. S., Covarelli, Barbaro, De, Demina, P., Eshaq, R., Garcia, Bellido, Goldenzweig, A., Han, P., Harel, J., Miner, A., D. C., Vishnevskiy, Zielinski, D., Bhatti, M., Ciesielski, A., Demortier, R., Goulianos, L., Lungu, K., Malik, G., Mesropian, S., Arora, C., Barker, S., Chou, A., Contreras, Campana, Duggan, E., Ferencek, D., Gershtein, D., Gray, Y., Halkiadakis, R., Hidas, E., Lath, D., Panwalkar, A., Park, S., Patel, M., Rekovic, R., Richards, V., Robles, A., Rose, J., Salur, K., Schnetzer, S., Seitz, S., Somalwar, C., Stone, S., Thomas, R., Cerizza, S., Hollingsworth, G., Spanier, M., Z. C., York, Eusebi, A., Flanagan, R., Gilmore, W., Kamon, J., Khotilovich, T., Montalvo, V., Osipenkov, R., Pakhotin, I., Perloff, Y., Roe, A., Safonov, J., Sakuma, A., Sengupta, T., Suarez, S., Tatarinov, I., Toback, A., Akchurin, D., Damgov, N., Dudero, J., P. R., Jeong, Kovitanggoon, C., Lee, K., S. W., Libeiro, Roh, T., Volobouev, Y., Appelt, I., Engh, E., Florez, D., Greene, C., Gurrola, S., Johns, A., Johnston, W., Kurt, C., Maguire, P., Melo, C., Sheldon, A., Snook, P., Tuo, B., Velkovska, S., Arenton, J., M. W., Balazs, Boutle, M., Cox, S., Francis, B., Goodell, B., Hirosky, J., Ledovskoy, R., Lin, A., Neu, C., Wood, C., Yohay, J., Gollapinni, R., Harr, S., Karchin, R., P. E., Kottachchi Kankanamge Don, Lamichhane, C., Sakharov, P., Anderson, A., Bachtis, M., Belknap, M., Borrello, D., Carlsmith, L., Cepeda, D., Dasu, M., Gray, S., Grogg, L., K. S., Grothe, Hall, Wilton, Herndon, R., Hervé, M., Klabbers, A., Klukas, P., Lanaro, J., Lazaridis, A., Leonard, C., Loveless, J., Mohapatra, R., Ojalvo, A., Palmonari, I., Pierro, F., G. A., Ross, Savin, I., Smith, A., W. H., Swanson, Guo S, J., Guo, Y, Li, W, Mao, Y, Qian, Sj, Teng, H, Zhang, L, Zhu, B, Zou, W, Cabrera, A, Moreno, Bg, Rios, Aao, Oliveros, Afo, Sanabria, Jc, Godinovic, N, Lelas, D, Lelas, K, Plestina, R, Polic, D, Puljak, I, Antunovic, Z, Dzelalija, M, Brigljevic, V, Duric, S, Kadija, K, Morovic, S, Attikis, A, Galanti, M, Mousa, J, Nicolaou, C, Ptochos, F, Razis, Pa, Rykaczewski, H, Assran, Y, Mahmoud, Ma, Hektor, A, Kadastik, M, Kannike, K, Muentel, M, Raidal, M, Rebane, L, Azzolini, V, Eerola, P, Czellar, S, Harkonen, J, Heikkinen, A, Karimaki, V, Kinnunen, R, Klem, J, Kortelainen, Mj, Lampen, T, Lassila Perini, K, Lehti, S, Linden, T, Luukka, P, Maenpaa, T, Tuominen, E, Tuominiemi, J, Tuovinen, E, Ungaro, D, Wendland, L, Banzuzi, K, Korpela, A, Tuuva, T, Sillou, D, Besancon, M, Choudhury, S, Dejardin, M, Denegri, D, Fabbro, B, Faure, Jl, Ferri, F, Ganjour, S, Gentit, Fx, Givernaud, A, Gras, P, de Monchenault GH, Jarry, P, Locci, E, Malcles, J, Marionneau, M, Millischer, L, Rander, J, Rosowsky, A, Shreyber, I, Titov, M, Verrecchia, P, Baffioni, S, Beaudette, F, Bianchini, L, Bluj, M, Broutin, C, Busson, P, Charlot, C, Dahms, T, Dobrzynski, L, de Cassagnac RG, Haguenauer, M, Mine, P, Mironov, C, Ochando, C, Paganini, P, Sabes, D, Salerno, R, Sirois, Y, Thiebaux, C, Wyslouch, B, Zabi, A, Agram, Jl, Andrea, J, Besson, A, Bloch, D, Bodin, D, Brom, Jm, Cardaci, M, Chabert, Ec, Collard, C, Conte, E, Drouhin, F, Ferro, C, Fontaine, Jc, Gele, D, Goerlach, U, Greder, S, Juillot, P, Karim, M, Le Bihan AC, Mikami, Y, Van Hove, P, Fassi, F, Mercier, D, Baty, C, Beaupere, N, Bedjidian, M, Bondu, O, Boudoul, G, Boumediene, D, Brun, H, Chanon, N, Chierici, R, Contardo, D, Depasse, P, El Mamouni, H, Falkiewicz, A, Fay, J, Gascon, S, Ille, B, Kurca, T, Le Grand, T, Lethuillier, M, Mirabito, L, Perries, S, Sordini, V, Tosi, S, Tschudi, Y, Verdier, P, Xiao, H, Roinishvili, V, Lomidze, D, Anagnostou, G, Edelhoff, M, Feld, L, Heracleous, N, Hindrichs, O, Jussen, R, Klein, K, Merz, J, Mohr, N, Ostapchuk, A, Perieanu, A, Raupach, F, Sammet, J, Schael, S, Sprenger, D, Weber, H, Weber, M, Wittmer, B, Ata, M, Bender, W, Erdmann, M, Frangenheim, J, Hebbeker, T, Hinzmann, A, Hoepfner, K, Hof, C, Klimkovich, T, Klingebiel, D, Kreuzer, P, Lanske, D, Magass, C, Masetti, G, Merschmeyer, M, Meyer, A, Papacz, P, Pieta, H, Reithler, H, Schmitz, Sa, Sonnenschein, L, Steggemann, J, Teyssier, D, Bontenackels, M, Davids, M, Duda, M, Flugge, G, Geenen, H, Giffels, M, Ahmad, Wh, Heydhausen, D, Kress, T, Kuessel, Y, Linn, A, Nowack, A, Perchalla, L, Pooth, O, Rennefeld, J, Sauerland, P, Stahl, A, Thomas, M, Tornier, D, Zoeller, Mh, Martin, Ma, Behrenhoff, W, Behrens, U, Bergholz, M, Borras, K, Cakir, A, Campbell, A, Castro, E, Dammann, D, Eckerlin, G, Eckstein, D, Flossdorf, A, Flucke, G, Geiser, A, Glushkov, I, Hauk, J, Jung, H, Kasemann, M, Katkov, I, Katsas, P, Kleinwort, C, Kluge, H, Knutsson, A, Krucker, D, Kuznetsova, E, Lange, W, Lohmann, W, Mankel, R, Marienfeld, M, Melzer Pellmann IA, Meyer, Ab, Mnich, J, Mussgiller, A, Olzem, J, Parenti, A, Raspereza, A, Raval, A, Schmidt, R, Schoerner Sadenius, T, Sen, N, Stein, M, Tomaszewska, J, Volyanskyy, D, Walsh, R, Wissing, C, Autermann, C, Bobrovskyi, S, Draeger, J, Enderle, H, Gebbert, U, Kaschube, K, Kaussen, G, Klanner, R, Lange, J, Mura, B, Naumann Emme, S, Nowak, F, Pietsch, N, Sander, C, Schettler, H, Schleper, P, Schroder, M, Schum, T, Schwandt, J, Srivastava, Ak, Stadie, H, Steinbruck, G, Thomsen, J, Wolf, R, Barth, C, Bauer, J, Buege, V, Chwalek, T, De Boer, W, Dierlamm, A, Dirkes, G, Feindt, M, and Gruschke, J.
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Heavy-ions ,Nuclear and High Energy Physics ,Heavy Ion collision ,CMS experiment ,ROOT-S=7 TEV ,Physics::Instrumentation and Detectors ,CMS ,Physics ,ATLAS DETECTOR ,W bosons ,HEAVY-ION COLLISIONS ,PRODUCTION CROSS-SECTION ,Physics and Astronomy ,High Energy Physics::Experiment ,LHC ,Nuclear Experiment - Abstract
A measurement is presented of W-boson production in PbPb collisions carried out at a nucleon-nucleon (NN) centre-of-mass energy root S-NN of 2.76 TeV at the LHC using the CMS detector. In data corresponding to an integrated luminosity of 7.3 mu b(-1), the number of W -> mu v(mu) decays is extracted in the region of muon pseudorapidity vertical bar eta mu vertical bar < 2.1 and transverse momentum p(T)(mu) > 25 GeV/c. Yields of muons found per unit of pseudorapidity correspond to (159 +/- 10(stat.) +/- 12(syst.)) x 10(-8) W and (154 +/- 10(stat.) +/- 12(syst.)) x 10(-8) W- bosons per minimum-bias PbPb collision. The dependence of W production on the centrality of PbPb collisions is consistent with a scaling of the yield by the number of incoherent NN collisions. The yield of W bosons is also studied in a sample of pp interactions at root S = 2.76 TeV corresponding to an integrated luminosity of 231 nb(-1). The individual W+ and W- yields in PbPb and pp collisions are found to agree, once the neutron and proton content in Pb nuclei is taken into account. Likewise, the difference observed in the dependence of the positive and negative muon production on pseudorapidity is consistent with next-to-leading-order perturbative QCD calculations.
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- 2012
22. Contemporary Management of Stable Coronary Artery Disease
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Dario Tino Bertolone, Emanuele Gallinoro, Giuseppe Esposito, Pasquale Paolisso, Konstantinos Bermpeis, Cristina De Colle, Davide Fabbricatore, Niya Mileva, Chiara Valeriano, Daniel Munhoz, Marta Belmonte, Marc Vanderheyden, Jozef Bartunek, Jeroen Sonck, Eric Wyffels, Carlos Collet, Costantino Mancusi, Carmine Morisco, Nicola De Luca, Bernard De Bruyne, Emanuele Barbato, Bertolone, D. T., Gallinoro, E., Esposito, G., Paolisso, P., Bermpeis, K., De Colle, C., Fabbricatore, D., Mileva, N., Valeriano, C., Munhoz, D., Belmonte, M., Vanderheyden, M., Bartunek, J., Sonck, J., Wyffels, E., Collet, C., Mancusi, C., Morisco, C., De Luca, N., De Bruyne, B., and Barbato, E.
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Fractional flow reserve ,Computed Tomography Angiography ,Coronary Stenosis ,Chronic coronary syndrome ,Angina ,Coronary Angiography ,Coronary artery disease ,Percutaneous coronary intervention ,Fractional Flow Reserve, Myocardial ,Predictive Value of Tests ,Internal Medicine ,Humans ,Coronary computed tomography angiography ,Cardiology and Cardiovascular Medicine - Abstract
Coronary artery disease (CAD) continues to be the leading cause of mortality and morbidity in developed countries. Assessment of pre-test probability (PTP) based on patient's characteristics, gender and symptoms, help to identify more accurate patient's clinical likelihood of coronary artery disease. Consequently, non-invasive imaging tests are performed more appropriately to rule in or rule out CAD rather than invasive coronary angiography (ICA). Coronary computed tomography angiography (CCTA) is the first-line non-invasive imaging technique in patients with suspected CAD and could be used to plan and guide coronary intervention. Invasive coronary angiography remains the gold-standard method for the identification and characterization of coronary artery stenosis. However, it is recommended in patients where the imaging tests are non-conclusive, and the clinical likelihood is very high, remembering that in clinical practice, approximately 30 to 70% of patients with symptoms and/or signs of ischemia, referred to coronary angiography, have non obstructive coronary artery disease (INOCA). In this contest, physiology and imaging-guided revascularization represent the cornerstone of contemporary management of chronic coronary syndromes (CCS) patients allowing us to focus specifically on ischemia-inducing stenoses. Finally, we also discuss contemporary medical therapeutic approach for secondary prevention. The aim of this review is to provide an updated diagnostic and therapeutic approach for the management of patients with stable coronary artery disease.
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- 2022
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23. Arrhythmic safety of hydroxychloroquine in COVID-19 patients from different clinical settings
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Marco Valerio Mariani, Massimo Galli, Nazzareno Galiè, Marco Schiavone, Francesca Salghetti, Firat Duru, Ardan M. Saguner, Antonio Lanfranchi, Davide Fabbricatore, Spinello Antinori, Mattia Busana, Alfonso Bellia, Chiara Cogliati, Pierluigi Viale, Alessio Gasperetti, Gianfranco Mitacchione, Mauro Biffi, Claudio Tondo, Marco Tocci, Matteo Ziacchi, Giovanni B. Forleo, Carlo Lavalle, Giacomo Casalini, Gasperetti A., Biffi M., Duru F., Schiavone M., Ziacchi M., Mitacchione G., Lavalle C., Saguner A., Lanfranchi A., Casalini G., Tocci M., Fabbricatore D., Salghetti F., Mariani M.V., Busana M., Bellia A., Cogliati C.B., Viale P., Antinori S., Galli M., Galie N., Tondo C., Forleo G.B., and University of Zurich
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Male ,QT interval ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Settore MED/09 ,610 Medicine & health ,Clinical settings ,Arrhythmias ,030204 cardiovascular system & hematology ,2705 Cardiology and Cardiovascular Medicine ,law.invention ,Electrocardiography ,03 medical and health sciences ,Settore MED/13 ,2737 Physiology (medical) ,0302 clinical medicine ,Clinical Research ,law ,Physiology (medical) ,Internal medicine ,Intensive care ,Humans ,Medicine ,AcademicSubjects/MED00200 ,cardiovascular diseases ,030212 general & internal medicine ,SARS-CoV-2 ,business.industry ,COVID-19 ,Arrhythmias, Cardiac ,Hydroxychloroquine ,Middle Aged ,Intensive care unit ,COVID-19 Drug Treatment ,3. Good health ,Regimen ,Italy ,10209 Clinic for Cardiology ,Cardiology ,Qtc interval prolongation ,Female ,Cardiology and Cardiovascular Medicine ,business ,Arrhythmia ,medicine.drug - Abstract
Aims The aim of the study was to describe ECG modifications and arrhythmic events in COVID-19 patients undergoing hydroxychloroquine (HCQ) therapy in different clinical settings. Methods and results COVID-19 patients at seven institutions receiving HCQ therapy from whom a baseline and at least one ECG at 48+ h were available were enrolled in the study. QT/QTc prolongation, QT-associated and QT-independent arrhythmic events, arrhythmic mortality, and overall mortality during HCQ therapy were assessed. A total of 649 COVID-19 patients (61.9 ± 18.7 years, 46.1% males) were enrolled. HCQ therapy was administrated as a home therapy regimen in 126 (19.4%) patients, and as an in-hospital-treatment to 495 (76.3%) hospitalized and 28 (4.3%) intensive care unit (ICU) patients. At 36–72 and at 96+ h after the first HCQ dose, 358 and 404 ECGs were obtained, respectively. A significant QT/QTc interval prolongation was observed (P < 0.001), but the magnitude of the increase was modest [+13 (9–16) ms]. Baseline QT/QTc length and presence of fever (P = 0.001) at admission represented the most important determinants of QT/QTc prolongation. No arrhythmic-related deaths were reported. The overall major ventricular arrhythmia rate was low (1.1%), with all events found not to be related to QT or HCQ therapy at a centralized event evaluation. No differences in QT/QTc prolongation and QT-related arrhythmias were observed across different clinical settings, with non-QT-related arrhythmias being more common in the intensive care setting. Conclusion HCQ administration is safe for a short-term treatment for patients with COVID-19 infection regardless of the clinical setting of delivery, causing only modest QTc prolongation and no directly attributable arrhythmic deaths.
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- 2020
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24. Vascular Access and Closure Management for Electrophysiological Interventions: Small Interventions Big Impact.
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Fabbricatore D and Malaczynska-Rajpold K
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- Humans, Cardiac Catheterization methods, Electrophysiologic Techniques, Cardiac methods, Ultrasonography, Interventional methods, Vascular Closure Devices
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Purpose of the Review: This review examines the role of vascular access and closure management in cardiac electrophysiology (EP) procedures, emphasising their impact on patient outcomes and safety. It synthesises current evidence and highlights advancements, challenges, and opportunities in this critical area of EP practice., Recent Findings: Ultrasound-guided vascular access has significantly reduced complications and improved success rates compared to traditional methods. Vascular closure devices (VCDs) enable faster recovery and same-day discharge, becoming superior alternatives to manual compression. The "4P framework"- Plan, Prepare, Puncture, Protect- offers a structured approach to optimising vascular access. Alternative techniques, such as transhepatic and jugular access, are feasible in complex cases, though large-scale evidence is limited. Vascular access management is essential for EP procedures, demanding adequate planning and execution. While advancements in imaging and closure techniques enhance outcomes, further research is needed to standardise practices and evaluate long-term results. A personalised, systematic approach ensures optimal procedural success and patient care., Competing Interests: Declarations. Human and Animal Rights and Informed Consent: This article does not contain any studies with human participants or animals performed by any of the authors. As this is a review article, informed consent is not applicable. Competing Interests: The authors declare no competing interests., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2025
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25. The Impact of Coronary Ischemia Assessment on Outcomes in Those With Scar-Dependent Ventricular Tachycardia.
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Waight MC, Fabbricatore D, Behr ER, Sohal M, Li AC, and Saba MM
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- Humans, Male, Female, Retrospective Studies, Middle Aged, Aged, Risk Factors, Time Factors, Myocardial Ischemia mortality, Myocardial Ischemia diagnosis, Myocardial Ischemia physiopathology, Myocardial Ischemia complications, Myocardial Ischemia therapy, Predictive Value of Tests, Defibrillators, Implantable, Cicatrix physiopathology, Cicatrix diagnosis, Cicatrix mortality, Electric Countershock instrumentation, Electric Countershock mortality, Risk Assessment, Progression-Free Survival, Heart Failure mortality, Heart Failure diagnosis, Heart Failure physiopathology, Heart Failure therapy, Treatment Outcome, Tachycardia, Ventricular physiopathology, Tachycardia, Ventricular diagnosis, Tachycardia, Ventricular mortality, Tachycardia, Ventricular etiology, Tachycardia, Ventricular therapy, Recurrence
- Abstract
Background: Guidance and outcomes of coronary ischemia assessment (IA) in those with structural heart disease (SHD), presenting with monomorphic ventricular tachycardia (MMVT) is unclear., Objectives: To assess the impact of IA on arrhythmic and non-arrhythmic outcomes in those with SHD., Methods: Patients presenting with MMVT over a 6-year period to a tertiary center were retrospectively analyzed. Propensity score-matched analysis was performed comparing those undergoing IA to those who did not. The primary endpoint was a composite of VT recurrence, appropriate ICD therapy, heart failure hospitalization, and death. Secondary analysis of the individual components of the composite was performed. Kaplan-Meier, univariate and multivariate analysis was performed to compare the two groups and derive predictors of poor outcomes., Results: Two hundred and seventeen patients (57.6% ICM) were analyzed. 55.8% underwent IA. Following propensity score-matching, 120 patients remained. At 12 months, freedom from the primary endpoint was 68.3% of those undergoing IA versus 43.3% who did not, p < 0.001, multivariate HR 0.56 (0.34-0.92). This was driven by a reduction in all-cause mortality, with a 12-month survival of 98.3% in those undergoing IA versus 86.5% in those not undergoing IA (p < 0.01). Coronary intervention was associated with a significantly higher event-free 12-month survival compared to those who did not undergo intervention (82.4% vs 51.5%, respectively, p = 0.01)., Conclusions: Patients with SHD presenting MMVT who undergo an IA have significantly improved freedom from VT recurrence, appropriate ICD therapies, HF hospitalization, and death compared to those who do not, driven by a reduction in mortality., (© 2024 The Author(s). Journal of Cardiovascular Electrophysiology published by Wiley Periodicals LLC.)
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- 2025
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26. Dual-chamber leadless pacemaker in complex adult congenital heart disease: a case report.
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Ngan HTA, Fabbricatore D, Regan W, Rosenthal E, and Wong T
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Background: Atrioventricular block is common with adult congenital heart disease and pacemaker implantation is challenging. Atrioventricular synchronous pacing is important for better haemodynamics. This case reports the implantation of a dual-chamber leadless pacemaker in a patient with univentricular heart physiology and contributes to the literature regarding the management option in complex adult congenital heart disease patients with conduction abnormalities., Case Summary: A 25-year-old male with double inlet left ventricular, transposition of great arteries, hypoplastic aortic arch receive multiple surgeries including the Glenn shunt at the age of 1. He presented with 2:1 and 3:1 heart block at the age of 13 with a transvenous dual-chamber pacemaker implanted by pacing the superior vena cava stump and puncturing the Glenn shunt for the ventricular lead. A decade later, lead malfunctioned and the patient progressed to complete heart block. A subcutaneous implantable cardioverter defibrillator was implanted when he was 23 for monomorphic ventricular tachycardia. Given the anticipated challenges with transvenous lead extraction and epicardial pacemaker implantation, we implanted the novel dual-chamber leadless pacemakers which resulted in satisfactory atrioventricular synchronous pacing performance immediately post-op and 2 weeks after the procedure., Discussion: We present a case of a novel dual-chamber leadless pacemaker implantation to maintain atrioventricular synchrony in the patient with complete heart block and univentricular physiology. This case illustrates an additional pacing option in complex adult congenital heart to maintain atrioventricular synchrony., Competing Interests: Conflict of interest: None declared., (© Crown copyright 2024.)
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- 2024
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27. High efficiency single-catheter workflow for radiofrequency atrial fibrillation ablation in the QDOT catheter era.
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Valeriano C, Buytaert D, Fabbricatore D, De Schouwer K, Addeo L, De Braekeleer L, Geelen P, and De Potter T
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- Humans, Male, Female, Middle Aged, Treatment Outcome, Feasibility Studies, Propensity Score, Aged, Equipment Design, Cohort Studies, Operative Time, Atrial Fibrillation surgery, Catheter Ablation methods, Catheter Ablation instrumentation, Workflow, Pulmonary Veins surgery
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Background: High-power short-duration (HPSD) ablation may improve the consistency and efficiency of pulmonary vein isolation (PVI). The novel QDOT Micro™ catheter (Biosense Webster, Inc.) with temperature feedback and microelectrodes aims to enhance PVI efficiency and safety. This study wants to evaluate the feasibility, safety, and efficiency of a standardized single-catheter workflow for PVI using QDOT (Q-FLOW)., Methods: The Q-FLOW includes single transeptal access, radiofrequency encircling of the PVs using a power of 50 W in a temperature/flow-controlled mode, and validation of the circles with microelectrodes. A 1:1 propensity-matched cohort of patients treated with conventional power-controlled ablation using a circular mapping catheter (CMC-FLOW) was used to compare procedural and clinical outcomes., Results: A total of 150 consecutive atrial fibrillation patients (paroxysmal 67%, persistent 33%) were included. First-pass isolation rate was 86%. Procedural time, X-ray time, and dose were significantly lower for the Q-FLOW vs the CMC-FLOW (67.2 ± 17.9 vs 88.3 ± 19.2 min, P < 0.001; 3.0 ± 1.9 vs 5.0 ± 2.4 min, P < 0.001; 4.3 ± 1.9 vs 6.4 ± 2.3 Gycm
2 , P < 0.001). Complications were numerically but not significantly lower in the Q-FLOW group (2 [1.3%] vs 7 [4.7%], P = 0.091). There was no difference in arrhythmia recurrence at 12 months (atrial arrhythmia-free survival rate, 87.5% vs 84.4%, P = 0.565)., Conclusion: A streamlined single-catheter workflow for PVI using QDOT was feasible and safe, resulting in a high rate of first-pass isolation and a low complication rate. The Q-FLOW further improved the efficiency of PVI compared to the standard CMC-FLOW, without difference in the 12-month outcome., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)- Published
- 2024
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28. Validation of an automated artificial intelligence system for 12‑lead ECG interpretation.
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Herman R, Demolder A, Vavrik B, Martonak M, Boza V, Kresnakova V, Iring A, Palus T, Bahyl J, Nelis O, Beles M, Fabbricatore D, Perl L, Bartunek J, and Hatala R
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- Humans, Electrocardiography, Neural Networks, Computer, Benchmarking, Artificial Intelligence, Acute Coronary Syndrome
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Background: The electrocardiogram (ECG) is one of the most accessible and comprehensive diagnostic tools used to assess cardiac patients at the first point of contact. Despite advances in computerized interpretation of the electrocardiogram (CIE), its accuracy remains inferior to physicians. This study evaluated the diagnostic performance of an artificial intelligence (AI)-powered ECG system and compared its performance to current state-of-the-art CIE., Methods: An AI-powered system consisting of 6 deep neural networks (DNN) was trained on standard 12‑lead ECGs to detect 20 essential diagnostic patterns (grouped into 6 categories: rhythm, acute coronary syndrome (ACS), conduction abnormalities, ectopy, chamber enlargement and axis). An independent test set of ECGs with diagnostic consensus of two expert cardiologists was used as a reference standard. AI system performance was compared to current state-of-the-art CIE. The key metrics used to compare performances were sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and F1 score., Results: A total of 932,711 standard 12‑lead ECGs from 173,949 patients were used for AI system development. The independent test set pooled 11,932 annotated ECG labels. In all 6 diagnostic categories, the DNNs achieved high F1 scores: Rhythm 0.957, ACS 0.925, Conduction abnormalities 0.893, Ectopy 0.966, Chamber enlargement 0.972, and Axis 0.897. The diagnostic performance of DNNs surpassed state-of-the-art CIE for the 13 out of 20 essential diagnostic patterns and was non-inferior for the remaining individual diagnoses., Conclusions: Our results demonstrate the AI-powered ECG model's ability to accurately identify electrocardiographic abnormalities from the 12‑lead ECG, highlighting its potential as a clinical tool for healthcare professionals., Competing Interests: Declaration of Competing Interest Dr. Herman is the Co-founder and Chief Medical Officer of Powerful Medical and supported by a research grant from the CardioPaTh PhD Program. Michal Martonak, Jakub Bahyl, Andrej Iring, Vladimir Boza and Anthony Demolder are employees of Powerful Medical. Other authors report no conflict of interest., (Copyright © 2023. Published by Elsevier Inc.)
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- 2024
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29. Coronary Microvascular Dysfunction in Patients With Heart Failure: Characterization of Patterns in HFrEF Versus HFpEF.
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Paolisso P, Gallinoro E, Belmonte M, Bertolone DT, Bermpeis K, De Colle C, Shumkova M, Leone A, Caglioni S, Esposito G, Fabbricatore D, Moya A, Delrue L, Penicka M, De Bruyne B, Barbato E, Bartunek J, and Vanderheyden M
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- Humans, Stroke Volume, Prospective Studies, Ventricular Function, Left, Heart Failure, Coronary Artery Disease
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Background: Coronary microvascular dysfunction (CMD) is involved in heart failure (HF) onset and progression, independently of HF phenotype and obstructive coronary artery disease. Invasive assessment of CMD might provide insights into phenotyping and prognosis of patients with HF. We aimed to assess absolute coronary flow, absolute microvascular resistance, myocardial perfusion, coronary flow reserve, and microvascular resistance reserve in patients with HF with preserved ejection fraction and HF with reduced ejection fraction (HFrEF)., Methods: Single-center, prospective study of 56 consecutive patients with de novo HF with nonobstructive coronary artery disease divided into HF with preserved ejection fraction (n=21) and HFrEF (n=35). CMD was invasively assessed by continuous intracoronary thermodilution and defined as coronary flow reserve <2.5. Left ventricular and left anterior descending artery-related myocardial mass was quantified by echocardiography and coronary computed tomography angiography. Myocardial perfusion (mL/min per g) was calculated as the ratio between absolute coronary flow and left anterior descending artery-related mass., Results: Patients with HFrEF showed a higher left ventricular and left anterior descending artery-related myocardial mass compared with HF with preserved ejection fraction ( P <0.010). Overall, 52% of the study population had CMD, with a similar prevalence between the 2 groups. In HFrEF, CMD was characterized by lower absolute microvascular resistance and higher absolute coronary flow at rest (functional CMD; P =0.002). CMD was an independent predictor of a lower rate of left ventricular reverse remodeling at follow-up. In patients with HF with preserved ejection fraction, CMD was mainly due to higher absolute microvascular resistance and lower absolute coronary flow during hyperemia (structural CMD; P ≤0.030)., Conclusions: Continuous intracoronary thermodilution allows the definition and characterization of patterns with distinct CMD in patients with HF and could identify patients with HFrEF with a higher rate of left ventricular reverse remodeling at follow-up., Competing Interests: Disclosures Drs Paolisso, Belmonte, Bertolone, Leone, Esposito, Fabbricatore, and Moya were supported by a research grant from the CardioPaTh PhD Program. Dr De Bruyne has a consulting relationship with Boston Scientific, Abbott Vascular, CathWorks, Siemens, and Coroventis Research; receives research grants from Abbott Vascular, Coroventis Research, CathWorks, and Boston Scientific; and holds minor equities in Philips Volcano, Siemens, GE Healthcare, Edwards Life Sciences, HeartFlow, Opsens, and Celiad. Dr Barbato declares speaker’s fees from Abbott Vascular, Boston Scientific, and GE Healthcare. Dr Bartunek reports consultancy fees from Occlutech, unrelated to the topic of the manuscript. The other authors report no conflicts.
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- 2024
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30. Innovative Device-Based Strategies for Managing Acute Decompensated Heart Failure.
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Bertolone DT, Paolisso P, Gallinoro E, Belmonte M, Bermpeis K, De Colle C, Esposito G, Caglioni S, Fabbricatore D, Leone A, Valeriano C, Shumkova M, Storozhenko T, Viscusi MM, Botti G, Verstreken S, Morisco C, Barbato E, Bartunek J, and Vanderheyden M
- Subjects
- Humans, Aged, Kidney, Hospitalization, Treatment Outcome, Acute Disease, Heart Failure
- Abstract
Acute decompensated heart failure (ADHF) is a major cause of hospitalizations in older adults, leading to high mortality, morbidity, and healthcare costs. To address the persistent poor outcomes in ADHF, novel device-based approaches targeting specific pathophysiological mechanisms are urgently needed. The recently introduced DRI
2 P2 S classification categorizes these innovative therapies based on their mechanisms. Devices include dilators (increasing venous capacitance), removers (directly removing sodium and water), inotropes (enhancing left ventricular contractility), interstitials (accelerating lymph removal), pushers (increasing renal arterial pressure), pullers (decreasing renal venous pressure), and selective drippers (selective intrarenal drug infusion). Some are tailored for chronic HF, while others focus on the acute setting. Most devices are in early development, necessitating further research to understand mechanisms, assess clinical effectiveness, and ensure safety before routine use in ADHF management. Exploring these innovative device-based strategies may lead to improved outcomes and revolutionize HF treatment in the future., Competing Interests: Declaration of Competing Interest DTB, PP, MB, GE, DF, CV, AL and MMV are supported by a research grant from the CardioPaTh PhD Program. The remaining authors have nothing to declare., (Copyright © 2023 Elsevier Inc. All rights reserved.)- Published
- 2023
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31. Association of Mild-to-Moderate Aortic Regurgitation With Outcomes in Heart Failure With Preserved Ejection Fraction.
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De Colle C, Paolisso P, Gallinoro E, Bertolone DT, Mileva N, Fabbricatore D, Valeriano C, Herman R, Beles M, De Oliveira EK, Mancusi C, Heggermont W, Collet C, Vanderheyden M, De Luca N, Van Camp G, Barbato E, Bartunek J, and Penicka M
- Subjects
- Humans, Stroke Volume, Prospective Studies, Echocardiography, Ventricular Function, Left, Heart Failure complications, Heart Failure epidemiology, Heart Failure drug therapy, Aortic Valve Insufficiency complications, Aortic Valve Insufficiency epidemiology
- Abstract
Objective: To assess aortic regurgitation (AR) prevalence, its hemodynamic effect, and long-term prognostic implications in patients admitted with de novo or worsened heart failure with preserved ejection fraction (HFpEF)., Methods: Consecutive patients hospitalized with de novo or worsened HFpEF between 2014 and 2020 were enrolled. Patients with more than moderate aortic and/or mitral valve disease were excluded. Based on the presence and degree of AR, patients were divided into those without AR, those with mild, and those with moderate AR. Data on cardiovascular death, heart failure (HF) rehospitalization, and their composite (major adverse cardiovascular events) were collected., Results: The final study population consisted of 458 HFpEF patients: 156 (34.1%) with mild-AR, 153 (33.4%) with moderate-AR, and the remaining 149 (32.5%) with no AR. Mild-to-moderate AR patients were older, with larger left atrium-left ventricle (LV) volumes, greater LV mass index, higher filling pressure, and prevalence of diastolic dysfunction compared with the no-AR group (all P<.05). During 5-year follow-up, 113 patients died of cardiovascular causes, 124 patients were rehospitalized for HF, whereas 196 experienced the composite endpoint. Mild-to-moderate AR was identified as an independent predictor of all-cause death (HR, 1.62; 95% CI, 1.14 to 1.58; P=.04) and major adverse cardiovascular event occurrence (HR, 1.48; 95% CI, 1.05 to 2.09; P=.02). A total of 126 (35.5%) of 355 patients showed progression of AR at follow-up echocardiography., Conclusion: Mild-to-moderate AR is common among patients hospitalized for HFpEF. It is associated with adverse LV remodeling and worse long-term outcomes. These findings warrant further prospective studies addressing the importance of AR in prognostic stratification and exploring therapeutic strategies to mitigate its hemodynamic effect on HF., (Copyright © 2023. Published by Elsevier Inc.)
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- 2023
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32. Pre-cath Laboratory Planning for Left Atrial Appendage Occlusion - Optional or Essential?
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Devgun J, De Potter T, Fabbricatore D, and Wang DD
- Subjects
- Humans, Treatment Outcome, Artificial Intelligence, Echocardiography, Transesophageal methods, Cardiac Catheterization methods, Atrial Appendage diagnostic imaging, Atrial Appendage surgery, Atrial Fibrillation diagnostic imaging, Atrial Fibrillation surgery
- Abstract
In the wake of rapid advancement in cardiovascular procedural technologies, physician-led preprocedural planning utilizing multi-modality imaging training is increasingly recognized as invaluable for procedural accuracy. Left atrial appendage occlusion (LAAO) is one such procedure in which complications such as device leak, cardiac injury, and device embolization can be decreased substantially with incorporation of physician driven imaging and digital tools. We discuss the benefits of cardiac CT and 3D printing in preprocedural planning for the Heart Team, as well as novel applications by physicians of intraprocedural 3D angiography and dynamic fusion imaging. Furthermore, incorporation of computational modeling and artificial intelligence (AI) may yield promise. For optimal patient-centric procedural success, we advocate for standardized preprocedural imaging planning by physicians within the Heart Team as an essential part of LAAO., Competing Interests: Disclosure Dr D.D. Wang is a consultant for Edwards Lifesciences, Boston Scientific, Abbott, and Neochord. Dr D.D. Wang receives a research grant from Boston Scientific assigned to employer Henry Ford Health System not associated with this article. Dr T. De Potter consults for and received research grants not associated with this article from Boston Scientific, for which all invoices and payments are made directly to nonprofit “Cardiovascular Research Institute Aalst.” All other authors report no relevant financial disclosures., (Copyright © 2023 Elsevier Inc. All rights reserved.)
- Published
- 2023
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33. Ambulatory pulmonary vein isolation workflow using the Perclose ProglideTM suture-mediated vascular closure device: the PRO-PVI study.
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Fabbricatore D, Buytaert D, Valeriano C, Mileva N, Paolisso P, Nagumo S, Munhoz D, Collet C, and De Potter T
- Subjects
- Humans, Sutures, Treatment Outcome, Workflow, Pulmonary Veins surgery, Vascular Closure Devices
- Abstract
Aims: The leading reason for delayed discharge after pulmonary vein isolation (PVI) is vascular complications. This study aimed to evaluate feasibility, safety, and efficacy of the Perclose Proglide™ suture-mediated vascular closure in ambulatory PVI, report complications, patient satisfaction, and cost of this approach., Methods and Results: Patients scheduled for PVI were enrolled prospectively in an observational design. Feasibility was assessed as % discharged the day of procedure. Efficacy was analysed as acute access site closure rate, time to reach haemostasis, time to ambulate, and time to discharge. Safety analysis consisted of vascular complications at 30 days. Cost analysis was reported using direct and indirect cost analysis. A 1:1 propensity matched control cohort was used for comparing time to discharge to usual workflow. Of 50 enrolled patients, 96% were discharged on the same day. 100% of devices were successfully deployed. Immediate (<1 min) haemostasis was reached in 30 patients (62.5%). Mean time to discharge was 5:48 ± 1:03 h (vs. 10:16 ± 1:21 h in the matched cohort, P < 0.0001). Patients reported high level of satisfaction with the post-operative time. No major vascular complication occurred. Cost analysis showed a neutral impact compared to the standard of care., Conclusion: The use of the closure device for femoral venous access after PVI led to safe discharge of patients within 6 h from the intervention in 96% of the population. This approach could minimize the overcrowding of healthcare facilities. The gain in post-operative recovery time improved patients' satisfaction and balanced the economic cost of the device., Competing Interests: Conflict of interest: The authors report no conflict of interest beyond the funding as reported in the manuscript., (© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.)
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- 2023
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34. Diagnostic and Prognostic Role of Cardiac Magnetic Resonance in MINOCA: Systematic Review and Meta-Analysis.
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Mileva N, Paolisso P, Gallinoro E, Fabbricatore D, Munhoz D, Bergamaschi L, Belmonte M, Panayotov P, Pizzi C, Barbato E, Penicka M, Andreini D, and Vassilev D
- Subjects
- Female, Humans, Male, Middle Aged, Coronary Angiography methods, Myocardial Infarction diagnostic imaging, Myocardial Infarction epidemiology, Predictive Value of Tests, Prognosis, Risk Factors, Coronary Artery Disease diagnostic imaging, Coronary Artery Disease epidemiology, Coronary Vessels diagnostic imaging, Magnetic Resonance Spectroscopy methods, MINOCA diagnostic imaging, MINOCA epidemiology, Myocarditis diagnostic imaging, Myocarditis epidemiology, Takotsubo Cardiomyopathy diagnostic imaging, Takotsubo Cardiomyopathy epidemiology
- Abstract
Background: Myocardial infarction with nonobstructive coronary arteries (MINOCA) is common in current clinical practice. Cardiac magnetic resonance (CMR) plays an important role in its management and is increasingly recommended by all the current guidelines. However, the prognostic value of CMR in patients with MINOCA is still undetermined., Objectives: The purpose of this study was to determine the diagnostic and prognostic value of CMR in the management of patients with MINOCA., Methods: A systematic review was performed to identify studies reporting the results of CMR findings in patients with MINOCA. Random effects models were used to determine the prevalence of different disease entities: myocarditis, myocardial infarction (MI), or takotsubo syndrome. Pooled odds ratios (ORs) and 95% CIs were calculated to evaluate the prognostic value of CMR diagnosis in the subgroup of studies that reported clinical outcomes., Results: A total of 26 studies comprising 3,624 patients were included. The mean age was 54.2 ± 5.3 years, and 56% were men. MINOCA was confirmed in only 22% (95% CI: 0.17-0.26) of the cases and 68% of patients with initial MINOCA were reclassified after the CMR assessment. The pooled prevalence of myocarditis was 31% (95% CI: 0.25-0.39), and takotsubo syndrome 10% (95% CI: 0.06-0.12). In a subgroup analysis of 5 studies (770 patients) that reported clinical outcomes, CMR diagnosis of confirmed MI was associated with an increased risk of major adverse cardiovascular events (pooled OR: 2.40; 95% CI: 1.60-3.59)., Conclusions: In patients with MINOCA, CMR has been demonstrated to add an important diagnostic and prognostic value, proving to be crucial for the diagnosis of this condition. Sixty-eight percent of patients with initial MINOCA were reclassified after the CMR evaluation. CMR-confirmed diagnosis of MINOCA was associated with an increased risk of major adverse cardiovascular events at follow-up., Competing Interests: Funding Support and Author Disclosures Dr Mileva has received speaker fees from Abbott. Drs Paolisso, Fabbricatore, and Munhoz have received research grants provided by the Cardiopath PhD program. Dr Andreini has received research grants from GE Healthcare and Bracco. Dr Marta Belmonte has received a research grant from the Cardiopath PhD program. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose., (Copyright © 2023 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.)
- Published
- 2023
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35. Risk factors for Gram-negative bacterial infection of cardiovascular implantable electronic devices: multicentre observational study (CarDINe Study).
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Pascale R, Toschi A, Aslan AT, Massaro G, Maccaro A, Fabbricatore D, Dell'Aquila A, Ripa M, Işık ME, Kızmaz YU, Iacopino S, Camici M, Perna F, Akinosoglou K, Karruli A, Papadimitriou-Olivgeris M, Kayaaslan B, Bilir YA, Evren Özcan E, Turan OE, Işık MC, Pérez-Rodríguez MT, Yagüe BL, Quirós AM, Yılmaz M, Petersdorf S, De Potter T, Durante-Mangoni E, Akova M, Curnis A, Gibertoni D, Diemberger I, Scudeller L, Viale P, and Giannella M
- Subjects
- Humans, Fluorodeoxyglucose F18, Positron Emission Tomography Computed Tomography adverse effects, Positron Emission Tomography Computed Tomography methods, Retrospective Studies, Radiopharmaceuticals, Risk Factors, Obesity, Defibrillators, Implantable adverse effects, Defibrillators, Implantable microbiology, Cardiovascular Infections, Gram-Negative Bacterial Infections epidemiology, Gram-Negative Bacterial Infections complications, Prosthesis-Related Infections epidemiology, Prosthesis-Related Infections diagnosis
- Abstract
Background: Infections of cardiovascular implantable electronic devices (CIED) are mainly due to Gram-positive bacteria (GPB). Data about Gram-negative bacteria CIED (GNB-CIED) infections are limited. This study aimed to investigate risk factors, clinical and diagnostic characteristics, and outcome of patients with GNB-CIED., Methods: A multicentre, international, retrospective, case-control-control study was performed on patients undergoing CIED implantation from 2015 to 2019 in 17 centres across Europe. For each patient diagnosed with GNB-CIED, one matching control with GPB-CIED infection and two matching controls without infection were selected., Results: A total of 236 patients were enrolled: 59 with GNB-CIED infection, 59 with GPB-CIED infection and 118 without infection. No between-group differences were found regarding clinical presentation, diagnostic and therapeutic management. A trend toward a higher rate of fluorodeoxyglucose positron emission computed tomography (FDG PET/CT) positivity was observed among patients with GNB than in those with GPB-CIED infection (85.7% vs. 66.7%; P = 0.208). Risk factors for GNB-CIED infection were Charlson Comorbidity Index Score (relative risk reduction, RRR = 1.211; P = 0.011), obesity (RRR = 5.122; P = 0.008), ventricular-pacing ventricular-sensing inhibited-response pacemaker implantation (RRR = 3.027; P = 0.006) and right subclavian vein site of implantation (RRR = 5.014; P = 0.004). At 180-day survival analysis, GNB-CIED infection was associated with increased mortality risk (HR = 1.842; P = 0.067)., Conclusions: Obesity, high number of comorbidities and right subclavian vein implantation site were associated with increased risk of GNB-CIED infection. A prompt therapeutic intervention that may be guided using FDG PET/CT is suggested in patients with GNB-CIED infection, considering the poorer outcome observed in this group., Competing Interests: Competing Interests All the authors report no conflicts of interest., (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
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- 2023
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36. Absolute coronary flow and microvascular resistance reserve in patients with severe aortic stenosis.
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Paolisso P, Gallinoro E, Vanderheyden M, Esposito G, Bertolone DT, Belmonte M, Mileva N, Bermpeis K, De Colle C, Fabbricatore D, Candreva A, Munhoz D, Degrieck I, Casselman F, Penicka M, Collet C, Sonck J, Mangiacapra F, de Bruyne B, and Barbato E
- Subjects
- Humans, Coronary Circulation physiology, Coronary Vessels diagnostic imaging, Echocardiography methods, Hypertrophy, Left Ventricular diagnostic imaging, Hypertrophy, Left Ventricular etiology, Blood Flow Velocity physiology, Aortic Valve Stenosis diagnostic imaging, Aortic Valve Stenosis complications, Coronary Stenosis
- Abstract
Background: Development of left ventricle (LV) hypertrophy in aortic stenosis (AS) is accompanied by adaptive coronary flow regulation. We aimed to assess absolute coronary flow, microvascular resistance, coronary flow reverse (CFR) and microvascular resistance reserve (MRR) in patients with and without AS., Methods: Absolute coronary flow and microvascular resistance were measured by continuous thermodilution in 29 patients with AS and 29 controls, without AS, matched for age, gender, diabetes and functional severity of epicardial coronary lesions. Myocardial work, total myocardial mass and left anterior descending artery (LAD)-specific mass were quantified by echocardiography and cardiac-CT., Results: Patients with AS presented a significantly positive LV remodelling with lower global longitudinal strain and global work efficacy compared with controls. Total LV myocardial mass and LAD-specific myocardial mass were significantly higher in patients with AS (p=0.001). Compared with matched controls, absolute resting flow in the LAD was significantly higher in the AS cohort (p=0.009), resulting into lower CFR and MRR in the AS cohort compared with controls (p < 0.005 for both). No differences were found in hyperaemic flow and resting and hyperaemic resistances. Hyperaemic myocardial perfusion (calculated as the ratio between the absolute coronary flow subtended to the LAD, expressed in mL/min/g), but not resting, was significantly lower in the AS group (p=0.035)., Conclusions: In patients with severe AS and non-obstructive coronary artery disease, with the progression of LV hypertrophy, the compensatory mechanism of increased resting flow maintains adequate perfusion at rest, but not during hyperaemia. As a consequence, both CFR and MRR are significantly impaired., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2022
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37. Safety of Right and Left Ventricular Endomyocardial Biopsy in Heart Transplantation and Cardiomyopathy Patients.
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Bermpeis K, Esposito G, Gallinoro E, Paolisso P, Bertolone DT, Fabbricatore D, Mileva N, Munhoz D, Buckley J, Wyffels E, Sonck J, Collet C, Barbato E, De Bruyne B, Bartunek J, and Vanderheyden M
- Subjects
- Humans, Female, Retrospective Studies, Tissue Donors, Biopsy adverse effects, Heart Transplantation, Heart Failure, Cardiomyopathies, Heart Diseases
- Abstract
Background: Endomyocardial biopsy (EMB) facilitates a histopathologic diagnosis with unique prognostic and therapeutic implications in both native and donor hearts. It is a relatively safe procedure, with an overall complication rate ranging from <1% to 6% depending on the experience of the operator, the clinical status of the patient, the presence or absence of left bundle branch block, the access site, and the site of procurement (right ventricular [RV] vs left ventricular [LV] approach)., Objectives: This study aimed to assess the incidence of procedure-related complications in a real-world population. EMBs were performed either for surveillance of rejection episodes after heart transplantation or for diagnosis of etiology of cardiomyopathy., Methods: The authors retrospectively analyzed 1,368 biopsies obtained in 561 consecutive patients between May 2011 and May 2021. Patients were stratified according to the underlying heart disease, sex, age, access site, body mass index, and RV vs LV approach., Results: The analysis revealed an overall complication rate of 4.1%. Serious life-threatening cardiac complications occurred in <1% of EMBs, with tamponade necessitating pericardiocentesis in 0.2% and urgent cardiac surgery in 0.1% of the procedures. Minor complications occurred in 3.3% of the overall population and were more often encountered during LV EMBs (3.9%) and when the native heart was sampled (5.3%)., Conclusions: In experienced hands, LV and RV EMB for heart transplantation rejection surveillance and cardiomyopathy diagnosis is a safe procedure with low risk of complications. Older, female patients and those undergoing native heart EMB were more prone to complications following EMB., Competing Interests: Funding Support and Author Disclosures Drs Paolisso, Esposito, Bertolone, and Fabbricatore are supported by a research grant from the CardioPaTh PhD Program. Dr De Bruyne owns minor equity in Philips Volcano, Siemens, GE Healthcare, Edwards Lifesciences, HeartFlow, Opsens, and Celiad. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose., (Copyright © 2022 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.)
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- 2022
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38. Deferral of Coronary Revascularization in Patients With Reduced Ejection Fraction Based on Physiological Assessment: Impact on Long-Term Survival.
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Gallinoro E, Paolisso P, Di Gioia G, Bermpeis K, Fernandez-Peregrina E, Candreva A, Esposito G, Fabbricatore D, Bertolone DT, Bartunek J, Vanderheyden M, Wyffels E, Sonck J, Collet C, De Bruyne B, and Barbato E
- Subjects
- Coronary Angiography methods, Humans, Myocardial Revascularization, Stroke Volume, Treatment Outcome, Ventricular Function, Left, Coronary Artery Disease diagnosis, Coronary Artery Disease surgery, Coronary Stenosis diagnostic imaging, Coronary Stenosis surgery, Fractional Flow Reserve, Myocardial physiology
- Abstract
Background Deferring revascularization in patients with nonsignificant stenoses based on fractional flow reserve (FFR) is associated with favorable clinical outcomes up to 15 years. Whether this holds true in patients with reduced left ventricular ejection fraction is unclear. We aimed to investigate whether FFR provides adjunctive clinical benefit compared with coronary angiography in deferring revascularization of patients with intermediate coronary stenoses and reduced left ventricular ejection fraction. Methods and Results Consecutive patients with reduced left ventricular ejection fraction (≤50%) undergoing coronary angiography between 2002 and 2010 were screened. We included patients with at least 1 intermediate coronary stenosis (diameter stenosis ≥40%) in whom revascularization was deferred based either on angiography plus FFR (FFR guided) or angiography alone (angiography guided). The primary end point was the cumulative incidence of all-cause death at 10 years. The secondary end point (incidence of major adverse cardiovascular and cerebrovascular events) was a composite of all-cause death, myocardial infarction, any revascularization, and stroke. A total of 840 patients were included (206 in the FFR-guided group and 634 in the angiography-guided group). Median follow-up was 7 years (interquartile range, 3.22-11.08 years). After 1:1 propensity-score matching, baseline characteristics between the 2 groups were similar. All-cause death was significantly lower in the FFR-guided group compared with the angiography-guided group (94 [45.6%] versus 119 [57.8%]; hazard ratio [HR], 0.65 [95% CI, 0.49-0.85]; P <0.01). The rate of major adverse cardiovascular and cerebrovascular events was lower in the FFR-guided group (123 [59.7%] versus 139 [67.5%]; HR, 0.75 [95% CI, 0.59-0.95]; P =0.02). Conclusions In patients with reduced left ventricular ejection fraction, deferring revascularization of intermediate coronary stenoses based on FFR is associated with a lower incidence of death and major adverse cardiovascular and cerebrovascular events at 10 years.
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- 2022
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39. Prospective evaluation of the learning curve and diagnostic accuracy for Pre-TAVI cardiac computed tomography analysis by cardiologists in training: The LEARN-CT study.
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Paolisso P, Gallinoro E, Andreini D, Mileva N, Esposito G, Bermpeis K, Bertolone DT, Munhoz D, Belmonte M, Fabbricatore D, Sonck J, Collet C, Penicka M, De Bruyne B, Vanderheyden M, and Barbato E
- Subjects
- Aortic Valve, Humans, Learning Curve, Predictive Value of Tests, Reproducibility of Results, Tomography, X-Ray Computed methods, Aortic Valve Stenosis, Cardiologists, Heart Valve Prosthesis
- Abstract
Background: To investigate the learning curve and the minimum number of cases required for a cardiologist in training to acquire the skills to an accurate pre-TAVI cardiac CT (CCT) analysis using a semi-automatic software., Methods: In this prospective, observational study, 40 CCTs of patients scheduled for TAVI were independently evaluated twice by 5 readers (80 readings each, 400 in total): a certified TAVI-CT specialist served as the reference reader (RR) and 4 cardiology fellows (2 interventional and 2 non-invasive cardiac imaging) as readers. The primary outcome was the minimum number of cases required to achieve an accuracy in imaging interpretation ≥80%, defined as the agreement between each reader and the RR in both balloon and self-expandable valve size choice. The secondary outcomes were the intra- and inter-observer variability., Results: After 50 readings (25 cases repeated twice) cardiology fellows were able to select the appropriate valve size with ≥ 80% of accuracy compared to the RR, independently of valve calcification, image quality and slice thickness. Learning curves of both interventional and non-invasive cardiac imaging fellows showed a similar trend. Cardiology fellows achieved a very high intra- and inter-observer reliability for both perimeter and area assessment, with an intraclass correlation coefficient (ICC) ranging from 0.96 to 0.99., Conclusions: Despite the individual differences, cardiology fellows required 50 readings (25 cases repeated twice) to get adequately skilled in the pre-TAVI CCT interpretation. These results provide valuable information for developing adequate training sessions and education protocols for both companies and cardiologists involved., Competing Interests: Declaration of competing interest The authors declare that they have no competing interests., (Copyright © 2022 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.)
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- 2022
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40. Arrhythmic Storm Due to ICD Atrial Lead Malfunction.
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Fabbricatore D, Heggermont W, Buytaert D, Van Bockstal K, and De Potter T
- Abstract
We describe the case of a young woman with a dual-chamber implantable cardioverter-defibrillator for long-QT syndrome who was referred to our emergency department (Cardiovascular Research Centre of Aalst, Belgium) because of an "arrhythmic storm" caused by atrial lead fracture. This case highlights the importance of the correct choice of both the device type and the pacing modality. ( Level of Difficulty: Intermediate. )., Competing Interests: Dr Fabbricatore has received support from a research grant provided by the Cardiopath PhD program at the University of Naples Federico II. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose., (© 2022 The Authors.)
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- 2022
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41. Pre-cath Laboratory Planning for Left Atrial Appendage Occlusion - Optional or Essential?
- Author
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Devgun J, De Potter T, Fabbricatore D, and Wang DD
- Subjects
- Artificial Intelligence, Echocardiography, Transesophageal methods, Humans, Treatment Outcome, Atrial Appendage diagnostic imaging, Atrial Appendage surgery, Atrial Fibrillation surgery
- Abstract
In the wake of rapid advancement in cardiovascular procedural technologies, physician-led preprocedural planning utilizing multi-modality imaging training is increasingly recognized as invaluable for procedural accuracy. Left atrial appendage occlusion (LAAO) is one such procedure in which complications such as device leak, cardiac injury, and device embolization can be decreased substantially with incorporation of physician driven imaging and digital tools. We discuss the benefits of cardiac CT and 3D printing in preprocedural planning for the Heart Team, as well as novel applications by physicians of intraprocedural 3D angiography and dynamic fusion imaging. Furthermore, incorporation of computational modeling and artificial intelligence (AI) may yield promise. For optimal patient-centric procedural success, we advocate for standardized preprocedural imaging planning by physicians within the Heart Team as an essential part of LAAO., Competing Interests: Disclosure Dr D.D. Wang is a consultant for Edwards Lifesciences, Boston Scientific, Abbott, and Neochord. Dr D.D. Wang receives a research grant from Boston Scientific assigned to employer Henry Ford Health System not associated with this article. Dr T. De Potter consults for and received research grants not associated with this article from Boston Scientific, for which all invoices and payments are made directly to nonprofit “Cardiovascular Research Institute Aalst.” All other authors report no relevant financial disclosures., (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Published
- 2022
- Full Text
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42. Performance of non-invasive myocardial work to predict the first hospitalization for de novo heart failure with preserved ejection fraction.
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Paolisso P, Gallinoro E, Mileva N, Moya A, Fabbricatore D, Esposito G, De Colle C, Beles M, Spapen J, Heggermont W, Collet C, Van Camp G, Vanderheyden M, Barbato E, Bartunek J, and Penicka M
- Subjects
- Hospitalization, Humans, Stroke Volume physiology, Systole, Ventricular Function, Left physiology, Heart Failure diagnosis, Heart Failure therapy
- Abstract
Aims: Non-invasive myocardial work (MW) is a validated index of left ventricular (LV) systolic performance, incorporating afterload and myocardial metabolism. The role of MW in predicting the first hospitalization for de novo heart failure with preserved ejection fraction (HFpEF) is still unknown. We aim to investigate the diagnostic performance of MW to predict the first de novo HFpEF hospitalization in ambulatory individuals with preserved LV ejection fraction., Methods and Results: Twenty-nine patients with transthoracic echocardiography performed at least 6 months before the first HFpEF hospitalization were compared with 29 matched controls. MW was derived as the area of pressure-strain loop using speckle-tracking and brachial artery blood pressure. Global work index, global constructive work, global wasted work (GWW), and global work efficiency (GWE) were collected. First HFpEF hospitalization and its combination with cardiovascular death [major adverse cardiovascular events (MACE)] and all-cause of death [major adverse events (MAE)] were assessed. At baseline, future HFpEF patients showed lower global work index, global constructive work, GWE, and higher GWW than controls (all P < 0.05). At admission vs. baseline, GWE significantly decreased, and GWW increased in the HFpEF group (P < 0.05), whereas no significant difference was observed in the controls over time. GWW, with a cut-off of 170 mmHg%, showed the largest area under the curve (AUC) to predict first HFpEF hospitalization [AUC = 0.80, 95% confidence interval (CI) 0.69-0.91, P < 0.001], MACE (AUC = 0.80, 95% CI 0.66-0.90, P < 0.001), and MAE (AUC = 0.79, 95% CI 0.62-0.88, P = 0.001). GWW > 170 mmHg% was associated with a 4-fold increase of MACE (HR = 4.5, 95% CI 1.59-13.12, P = 0.005) and a 3-fold higher risk of MAE (HR = 2.9, 95% CI 1.24-6.6, P = 0.014)., Conclusions: In ambulatory patients with preserved LV ejection fraction and risk factors, GWW showed high accuracy to predict the first HFpEF hospitalization and its combination with mortality. The GWW routine assessment may be clinically helpful in patients with dyspnoea., (© 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.)
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- 2022
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43. Microvascular Dysfunction in Patients With Type II Diabetes Mellitus: Invasive Assessment of Absolute Coronary Blood Flow and Microvascular Resistance Reserve.
- Author
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Gallinoro E, Paolisso P, Candreva A, Bermpeis K, Fabbricatore D, Esposito G, Bertolone D, Fernandez Peregrina E, Munhoz D, Mileva N, Penicka M, Bartunek J, Vanderheyden M, Wyffels E, Sonck J, Collet C, De Bruyne B, and Barbato E
- Abstract
Background: Coronary microvascular dysfunction (CMD) is an early feature of diabetic cardiomyopathy, which usually precedes the onset of diastolic and systolic dysfunction. Continuous intracoronary thermodilution allows an accurate and reproducible assessment of absolute coronary blood flow and microvascular resistance thus allowing the evaluation of coronary flow reserve (CFR) and Microvascular Resistance Reserve (MRR), a novel index specific for microvascular function, which is independent from the myocardial mass. In the present study we compared absolute coronary flow and resistance, CFR and MRR assessed by continuous intracoronary thermodilution in diabetic vs. non-diabetic patients. Left atrial reservoir strain (LASr), an early marker of diastolic dysfunction was compared between the two groups. Methods: In this observational retrospective study, 108 patients with suspected angina and non-obstructive coronary artery disease (NOCAD) consecutively undergoing elective coronary angiography (CAG) from September 2018 to June 2021 were enrolled. The invasive functional assessment of microvascular function was performed in the left anterior descending artery (LAD) with intracoronary continuous thermodilution. Patients were classified according to the presence of DM. Absolute resting and hyperemic coronary blood flow (in mL/min) and resistance (in WU) were compared between the two cohorts. FFR was measured to assess coronary epicardial lesions, while CFR and MRR were calculated to assess microvascular function. LAS, assessed by speckle tracking echocardiography, was used to detect early myocardial structural changes potentially associated with microvascular dysfunction. Results: The median FFR value was 0.83 [0.79-0.87] without any significant difference between the two groups. Absolute resting and hyperemic flow in the left anterior descending coronary were similar between diabetic and non-diabetic patients. Similarly, resting and hyperemic resistances did not change significantly between the two groups. In the DM cohort the CFR and MRR were significantly lower compared to the control group (CFR = 2.38 ± 0.61 and 2.88 ± 0.82; MRR = 2.79 ± 0.87 and 3.48 ± 1.02 for diabetic and non-diabetic patients respectively, [p < 0.05 for both]). Likewise, diabetic patients had a significantly lower reservoir, contractile and conductive LAS (all p < 0.05). Conclusions: Compared with non-diabetic patients, CFR and MRR were lower in patients with DM and non-obstructive epicardial coronary arteries, while both resting and hyperemic coronary flow and resistance were similar. LASr was lower in diabetic patients, confirming the presence of a subclinical diastolic dysfunction associated to the microcirculatory impairment. Continuous intracoronary thermodilution-derived indexes provide a reliable and operator-independent assessment of coronary macro- and microvasculature and might potentially facilitate widespread clinical adoption of invasive physiologic assessment of suspected microvascular disease., Competing Interests: CC reports receiving research grants from Biosensor, Coroventis Research, GE Healthcare, Medis Medical Imaging, Pie Medical Imaging, Cathworks, Boston Scientific, Siemens, HeartFlow Inc. and Abbott Vascular; and consultancy fees from Heart Flow Inc, Opsens, Pie Medical Imaging, Abbott Vascular and Philips Volcano. BD has a consulting relationship with Boston Scientific, Abbott Vascular, CathWorks, Siemens, and Coroventis Research; receives research grants from Abbott Vascular, Coroventis Research, Cathworks, Boston Scientific; and holds minor equities in Philips-Volcano, Siemens, GE Healthcare, Edwards Life Sciences, HeartFlow, Opsens, and Celiad. EB declares speaker's fees from Abbott Vascular, Boston Scientific and GE. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Gallinoro, Paolisso, Candreva, Bermpeis, Fabbricatore, Esposito, Bertolone, Fernandez Peregrina, Munhoz, Mileva, Penicka, Bartunek, Vanderheyden, Wyffels, Sonck, Collet, De Bruyne and Barbato.)
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- 2021
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44. Technical considerations for CRT-D implantation in different varieties of persistent left superior vena cava.
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Bontempi L, Aboelhassan M, Cerini M, Salghetti F, Fabbricatore D, Maiolo V, Ghizzoni G, and Curnis A
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- Brachiocephalic Veins, Cardiac Resynchronization Therapy Devices, Humans, Vena Cava, Superior diagnostic imaging, Vena Cava, Superior surgery, Cardiac Resynchronization Therapy, Persistent Left Superior Vena Cava
- Abstract
Purpose: The persistent left superior vena cava (PLSVC) is usually asymptomatic and creates a challenge when detected incidentally during cardiac resynchronization therapy defibrillator (CRT-D) implantation. The purpose of our cases is to show different anatomical variables of PLSVC and different strategies used for CRT-D implantation., Methods: Four cases of PLSVC were presented. Pre-procedural bilateral venography was done to define anatomical variant of PLSVC. The side of approach and vein of approach were chosen according to the anatomical variant. Major challenges, electrical parameters, procedural times, long-term follow up, and complications were addressed., Results: Two cases were de novo CRT-D implantation. One case was an extraction/re-implantation of the coil lead, and one case was an upgrading. In one case, CRT-D implantation was followed by AVN ablation. All cases had successful devices implantation. Two cases had isolated PLSVC: one of them had right approach and the other had left approach. One case had double SVC with no connecting brachiocephalic veins and underwent a left-sided approach. One case had double SVC with a small connecting brachiocephalic vein and had a left approach for implantation with using the small brachiocephalic vein for the RV lead. Electrical parameters were acceptable for all leads implanted. Long-term follow-up was done for 6 months to 5 years. One complication occurred (acute atrial lead dislodgement)., Conclusions: In our case series, the presence of PLSVC did not preclude successful placement of pacemaker/defibrillator leads using standard tools. Bilateral venography helped to decide the side and vein of lead insertion., (© 2020. Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2021
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45. Ultralow temperature cryoablation using near-critical nitrogen for cavotricuspid isthmus-ablation, first-in-human results.
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Klaver MN, De Potter TJR, Iliodromitis K, Babkin A, Cabrita D, Fabbricatore D, and Boersma LVA
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- Aged, Female, Humans, Male, Middle Aged, Nitrogen, Prospective Studies, Temperature, Treatment Outcome, Atrial Flutter diagnostic imaging, Atrial Flutter surgery, Catheter Ablation adverse effects, Cryosurgery adverse effects
- Abstract
Introduction: Cryoablation has evolved as a safe alternative to radiofrequency ablation in the treatment of several supraventricular arrhythmias and has potential advantages, yet is limited by the properties of the cryogen used. We investigated a novel ultralow temperature cryoablation (ULTC) system using nitrogen near its liquid-vapor critical point as a freezing source, achieving temperatures as low as -196 degrees Celsius in a long linear catheter with a continuous energy release. Initial safety, procedural and efficacy outcomes of ULTC are described in patients undergoing cavotricuspid isthmus (CTI) ablation., Methods and Results: The Cryocure studies (NCT02355106, NCT02839304) are prospective, single-arm, multi-center, first-in-human clinical studies in 17 patients with atrial flutter (AFL) and 13 patients with atrial fibrillation (AF). A total of 30 patients, mean age 65 ± 8 years old and 67% male, were enrolled and underwent ablation of the CTI. Acute success, defined as the confirmation of stable bidirectional conduction block across the CTI, was achieved in all 30 patients. After 12 months of follow-up, 14 out of 17 AFL patients remained free from any AFL. One (3.3%) procedure-related but not device-related serious adverse event was reported, involving transient inferolateral ST-elevation associated with temporary AV conduction block., Conclusion: In this first-in-human clinical study the safety and performance results demonstrate the capabilities of ultralow temperature near-critical nitrogen as an effective energy source for CTI ablation. Ongoing, larger, studies should confirm our findings and evaluate the capabilities to create linear and focal transmural lesions in other arrhythmias., (© 2021 The Authors. Journal of Cardiovascular Electrophysiology Published by Wiley Periodicals LLC.)
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- 2021
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46. Could Home Monitoring parameters provide information about the impact of the pandemic period on CIED patients? A comparison between 2019 and 2020.
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Bontempi L, Aboelhassan M, Cerini M, Salghetti F, Fabbricatore D, Maiolo V, Freda L, Giacopelli D, and Curnis A
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- Humans, Infection Control methods, Outcome and Process Assessment, Health Care, Remote Sensing Technology methods, SARS-CoV-2, Arrhythmias, Cardiac diagnosis, Arrhythmias, Cardiac epidemiology, Arrhythmias, Cardiac physiopathology, Arrhythmias, Cardiac therapy, COVID-19 epidemiology, COVID-19 prevention & control, Defibrillators, Implantable statistics & numerical data, Exercise physiology, Exercise statistics & numerical data, Monitoring, Ambulatory methods, Monitoring, Ambulatory statistics & numerical data, Monitoring, Ambulatory trends, Pacemaker, Artificial statistics & numerical data, Sedentary Behavior
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- 2021
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47. Transvenous lead extraction in patients with persistent left superior vena cava.
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Curnis A, Aboelhassan M, Cerini M, Salghetti F, Fabbricatore D, Maiolo V, Arabia G, Giacopelli D, Fouad DA, and Bontempi L
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- Device Removal, Fluoroscopy, Humans, Treatment Outcome, Persistent Left Superior Vena Cava, Vena Cava, Superior diagnostic imaging, Vena Cava, Superior surgery
- Abstract
Purpose: Predictors of difficulty and complications of transvenous lead extraction (TLE) have been investigated in several studies; however, little is known about the venous anatomical characteristics that can have an impact on procedural outcomes. Among them, the persistent left superior vena cava (PLSVC) is a common anomaly often discovered incidentally during cardiac device implantation and could raise concerns if TLE is indicated. We report technical considerations and outcomes of TLE for two patients with leads implanted via PLSVC., Methods and Results: Two cardiac implantable electronic device recipients with isolated PLSVC required TLE due to infective endocarditis in one case and lead failure in the other. In the first case, TLE procedure was performed in a hybrid operating room with minimally invasive video-assisted thoracoscopic monitoring due to the high procedural risk. Two active fixation 20-year-old pacing leads were removed with a relatively short fluoroscopy time. In the second case, we successfully extracted a single-coil active fixation lead without the need of a locking stylet or advanced extraction tools. There were no procedural complications or adverse events at 1-year follow-up., Conclusion: TLE procedures for two patients with isolated PLSVC were successfully completed with less difficulty and tools than expected based on the characteristics of the targeted leads. If indicated, TLE in the presence of a PLSVC should be considered in experienced centers., (© 2021 Wiley Periodicals LLC.)
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- 2021
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48. Use of a novel implantable cardioverter-defibrillator multisensor algorithm for heart failure monitoring in a COVID-19 patient: A case report.
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Bontempi L, Cerini M, Salghetti F, Fabbricatore D, Nozza C, Campari M, Valsecchi S, and Curnis A
- Abstract
We report the case of a patient implanted with an implantable defibrillator endowed with a multisensor algorithm for heart failure monitoring. Automatic measurement of multiple clinical variables allowed to detect impending heart failure decompensation and showed its ability to facilitate differential diagnosis in the context of the current COVID-19 pandemic., Competing Interests: C. Nozza, M. Campari, and S. Valsecchi are employee of Boston Scientific Italia. All the remaining authors have no major conflicts of interest to disclose., (© 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.)
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- 2021
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49. Leadless pacemaker: State of the art and incoming developments to broaden indications.
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Curnis A, Salghetti F, Cerini M, Fabbricatore D, Ghizzoni G, Arrigoni L, Generati G, Arabia G, Maiolo V, Aboelhassan M, and Bontempi L
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- Cardiac Pacing, Artificial, Equipment Design, Humans, Arrhythmias, Cardiac therapy, Pacemaker, Artificial
- Abstract
Theleadless pacemaker (LLPM) therapy has been developed in recent years to overcome the transvenous lead and device pocket-related complications. The LLPMs now available are self-contained right ventricular pacemakers and are limited to single-chamber ventricular pacing modality. This literature review deals with the current status of LLPM technology and current areas of clinical applicability. The safety and efficacy outcomes published from randomized clinical trials and real world registries are analyzed and compared with historical conventional transvenous pacemaker data. Furthermore, new pacing modalities and future perspectives to broaden the clinical use and cover most of pacing indications are discussed. Due to the overall safe and effective profile in the short term and intermediate term, also in fragile patients, the LLPM use is constantly growing in daily clinical practice. Actually, it can be considered a landmark innovation, through which a new era of cardiac pacing has begun., (© 2020 Wiley Periodicals LLC.)
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- 2020
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50. Abandoned and fractured ICD lead with complete superior veins occlusion: Is transvenous lead extraction still possible?
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Bontempi L, Aboelhassan M, Cerini M, Salghetti F, Arabia G, Fabbricatore D, Maiolo V, Giacopelli D, and Curnis A
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- Device Removal, Electrodes, Implanted, Equipment Failure, Humans, Retrospective Studies, Treatment Outcome, Veins, Defibrillators, Implantable adverse effects, Pacemaker, Artificial adverse effects
- Published
- 2020
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