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There is evidence that object-location memory consists of three separate processes, that is, positional memory, binding of objects to locations, and a possible integration mechanism. A group of 26 patients with lesions following ischaemic stroke was studied to find evidence for selective impairments in these three processes using displays with pictures of everyday objects on different locations. Moreover, object-recognition memory and visuospatial construction was assessed. The Corsi Block-Tapping Task and Oxford Stylus Maze Test were included as standard spatial-memory tests. The results showed that of these 26 patients, 8 patients had selective impairments in the aforementioned object-location memory task conditions (both after immediate and delayed testing). These data further support the existence of separate cognitive processes within memory for object locations that can be selectively affected by cerebral dysfunction.

There is evidence that object-location memory consists of three separate processes, that is, positional memory, binding of objects to locations, and a possible integration mechanism. A group of 26 patients with lesions following ischaemic stroke was studied to find evidence for selective impairments in these three processes using displays with pictures of everyday objects on different locations. Moreover, object-recognition memory and visuospatial construction was assessed. The Corsi Block-Tapping Task and Oxford Stylus Maze Test were included as standard spatial-memory tests. The results showed that of these 26 patients, 8 patients had selective impairments in the aforementioned object-location memory task conditions (both after immediate and delayed testing). These data further support the existence of separate cognitive processes within memory for object locations that can be selectively affected by cerebral dysfunction.

WOS: 000341676600010, This study presents the pioneering data on the neurological representation of grammatically marked evidentials with regard to their dissolution in agrammatic Broca's aphasia. Across two tasks, we investigated the production of finite verb inflections for evidential categories and identification of the information sources these evidential categories are mapped on in Turkish individuals with agrammatic aphasia. In Turkish, information source is grammatically marked for three different past contexts: direct perception, reportative, and inferential. The following research questions were explored: (1) is inflection for different evidential categories equally affected in Turkish agrammatic aphasia? (2) Is identifying the categories of information source impaired? Turkish agrammatic speakers and non-brain-damaged speakers (NBDs) were tested with a production and a source identification tasks. Our findings demonstrate that in Turkish agrammatic speakers the direct perception evidential was more affected in production than the inferential and reportative evidentials. However, the agrammatic speakers retained the ability to identify the source for the direct perception. We argue that information source values conveyed by evidential forms are impaired in agrammatic aphasia. These findings are discussed on the basis of earlier studies to time reference and tense in agrammatism

Background and objectives Recent studies found different associations of cognitive function with albuminuria or estimated GFR (eGFR). Most studies were limited to the elderly or did not take both renal variables into account. Therefore, this study analyzed the association of cognitive function with albuminuria and eGFR in community-dwelling persons aged 35 to 82 years.Design, setting, participants, & measurements This was a cross-sectional study comprising 4095 participants of the Prevention of Renal and Vascular End-Stage Disease (PREVEND) study. Cognitive function, measured with the Ruff Figural Fluency Test (RFFT), was treated as the dependent variable, and albuminuria and eGFR were treated as independent variables.Results The prevalence of albuminuria = 30 mg/24 h was 54%, 31%, and 15%, respectively. Mean eGFR (+/- SD) was 79 +/- 15 ml/min per 1.73 m(2). Because of interaction between albuminuria and age, analyses were performed per age tertile. After multivariate adjustment, albuminuria >= 30 mg/24 h, but not eGFR, was associated with lower RFFT score in the youngest tertile (B 5.3; 95% CI, -0.6 to -9.2; P = 0.05), but not in older tertiles. Moreover, subjects in the youngest tertile with increasing albuminaria (5-15 and >15 mg/24 h) before RFFT measurement had lower mean RFFT scores than subjects with stable albuminuria: mean difference -4.9 (P = 0.3) and -6.7 (P = 0.03), respectively.Conclusions In this community-based cohort, elevated albuminuria was associated with worse cognitive function in young but not in old persons. There was no association of eGFR with cognitive function. Clin J Am Soc Nephrol 6: 1400-1409, 2011. doi: 10.2215/QN.05530610

There is evidence that object-location memory consists of three separate processes, that is, positional memory, binding of objects to locations, and a possible integration mechanism. A group of 26 patients with lesions following ischaemic stroke was studied to find evidence for selective impairments in these three processes using displays with pictures of everyday objects on different locations. Moreover, object-recognition memory and visuospatial construction was assessed. The Corsi Block-Tapping Task and Oxford Stylus Maze Test were included as standard spatial-memory tests. The results showed that of these 26 patients, 8 patients had selective impairments in the aforementioned object-location memory task conditions (both after immediate and delayed testing). These data further support the existence of separate cognitive processes within memory for object locations that can be selectively affected by cerebral dysfunction.