6 results on '"FM Accardo"'
Search Results
2. Towards An Improvement of Hospital Services and Streamlining of Health Care Costs: The DRG Analysis in Italy
- Author
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M Bellavia, G Tomasello, P Damiani, F Damiani, A Geraci, FM Accardo, MC Gioviale, and AI Lo Monte
- Subjects
Hospital services ,Health ,Case ,indexes ,Italy ,Public aspects of medicine ,RA1-1270 - Abstract
The term Diagnosis-related Group (DRG) refers to a classification system used to assess hospital services with the aim of a better management of health care costs and improving performance. The DRG system focuses on the utilization of resources, and is not concerned with the specific type of care provided to the patient. This system highlights any diseconomies and eventual critical aspects of the hospital system. This article, starting from the history of heath care financing in Italy and pointing out the difficulty to define the "quality" of health care services, describes the variables used to evaluate correctly hospital performance based on the DRG system. These include Average Length of Stay, Average Daily Patient Load, Comparative Performance Index, and Case Mix Index.
- Published
- 2012
3. HSP10,HSP70 AND HSP90 IMMUNOHISTOCHEMICAL LEVELS CHANGE IN ULCERATIVE COLITIS AFTER THERAPY
- Author
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Carmelo Sciumè, Provvidenza Damiani, Felicia Farina, Anna Martorana, Marcello Romeo, Vito Rodolico, Fm Accardo, E. Conway de Macario, Giovanni Zummo, R De Luca, Monica Zerilli, Giuseppe Cicero, Giovanni Tomasello, Francesca Rappa, A.J.L. Macario, Giuseppe Modica, Giuseppe Bonaventura, Francesco Cappello, Tomasello, G, Sciumè, C, Rappa, F, Rodolico, V, Zerilli, M, Martorana, A, Cicero, G, De Luca, R, Damiani, P, Accardo, FM, Romeo, M, Farina, F, Bonaventura, G, Modica, G, Zummo, G, Convay de Macario, E, Macario, AJL, and Cappello, F
- Subjects
Histology ,Biophysics ,Down-Regulation ,Inflammation ,comorbidity ,Inflammatory bowel disease ,ulcerative colitis, heat shock proteins, Hsp, molecular chaperones, inflammation comorbidity ,Pathogenesis ,chemistry.chemical_compound ,Mesalazine ,ulcerative colitis, heat shock proteins, Hsp, molecular chaperones, inflammation, comorbidity ,Heat shock protein ,Chaperonin 10 ,Medicine ,Hsp ,Humans ,HSP70 Heat-Shock Proteins ,HSP90 Heat-Shock Proteins ,Colitis ,Mesalamine ,lcsh:QH301-705.5 ,ulcerative colitis ,business.industry ,Brief Report ,molecular chaperones ,Anti-Inflammatory Agents, Non-Steroidal ,Cell Biology ,medicine.disease ,Ulcerative colitis ,Immunohistochemistry ,digestive system diseases ,chemistry ,lcsh:Biology (General) ,inflammation ,Immunology ,heat shock proteins ,Biomarker (medicine) ,Colitis, Ulcerative ,medicine.symptom ,business - Abstract
Ulcerative colitis (UC) is a form of inflammatory bowel disease (IBD) characterized by damage of large bowel mucosa and frequent extra-intestinal autoimmune comorbidities. The role played in IBD pathogenesis by molecular chaperones known to interact with components of the immune system involved in inflammation is unclear. We previously demonstrated that mucosal Hsp60 decreases in UC patients treated with conventional therapies (mesalazine, probiotics), suggesting that this chaperonin could be a reliable biomarker useful for monitoring response to treatment, and that it might play a role in pathogenesis. In the present work we investigated three other heat shock protein/molecular chaperones: Hsp10, Hsp70, and Hsp90. We found that the levels of these proteins are increased in UC patients at the time of diagnosis and decrease after therapy, supporting the notion that these proteins deserve attention in the study of the mechanisms that promote the development and maintenance of IBD, and as biomarkers of this disease (e.g., to monitor response to treatment at the histological level).
- Published
- 2011
4. Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy.
- Author
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Tomasello G, Sciumé C, Rappa F, Rodolico V, Zerilli M, Martorana A, Cicero G, De Luca R, Damiani P, Accardo FM, Romeo M, Farina F, Bonaventura G, Modica G, Zummo G, Conway de Macario E, Macario AJ, and Cappello F
- Subjects
- Anti-Inflammatory Agents, Non-Steroidal pharmacology, Chaperonin 10 genetics, Chaperonin 10 ultrastructure, Colitis, Ulcerative physiopathology, Down-Regulation drug effects, HSP70 Heat-Shock Proteins genetics, HSP70 Heat-Shock Proteins ultrastructure, HSP90 Heat-Shock Proteins genetics, HSP90 Heat-Shock Proteins ultrastructure, Humans, Immunohistochemistry, Mesalamine pharmacology, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Chaperonin 10 metabolism, Colitis, Ulcerative drug therapy, HSP70 Heat-Shock Proteins metabolism, HSP90 Heat-Shock Proteins metabolism, Mesalamine therapeutic use
- Abstract
Ulcerative colitis (UC) is a form of inflammatory bowel disease (IBD) characterized by damage of large bowel mucosa and frequent extra-intestinal autoimmune comorbidities. The role played in IBD pathogenesis by molecular chaperones known to interact with components of the immune system involved in inflammation is unclear. We previously demonstrated that mucosal Hsp60 decreases in UC patients treated with conventional therapies (mesalazine, probiotics), suggesting that this chaperonin could be a reliable biomarker useful for monitoring response to treatment, and that it might play a role in pathogenesis. In the present work we investigated three other heat shock protein/molecular chaperones: Hsp10, Hsp70, and Hsp90. We found that the levels of these proteins are increased in UC patients at the time of diagnosis and decrease after therapy, supporting the notion that these proteins deserve attention in the study of the mechanisms that promote the development and maintenance of IBD, and as biomarkers of this disease (e.g., to monitor response to treatment at the histological level).
- Published
- 2011
- Full Text
- View/download PDF
5. Effects of antepartum electronic fetal monitoring on maternal emotional state.
- Author
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Mancuso A, De Vivo A, Fanara G, Denaro A, Laganà D, and Accardo FM
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- Adult, Anxiety epidemiology, Delivery, Obstetric, Female, Fetal Movement, Humans, Pregnancy, Pregnancy Complications epidemiology, Pregnancy Complications psychology, Prenatal Care, Psychiatric Status Rating Scales, Regression Analysis, Smoking epidemiology, Surveys and Questionnaires, Cardiotocography, Mothers psychology
- Abstract
Background: To evaluate the emotional state of pregnant women undergoing computerised cardiotocography (cCTG)., Methods: A questionnaire including questions about socio-demographic background, personal obstetric history and physician-patient relationship was given to 204 pregnant women about to undergo cCTG. The Edinburgh Post-natal Depression Scale (EPDS) was used to assess patients' mood state before CTG, while the Spielberger State-Trait Anxiety Inventory (STAI) was used to evaluate anxiety levels before and after this examination., Results: Mean STAI T-anxiety score did not differ before and after CTG (p=0.38), but higher levels of basal anxiety were found in women who had undergone only occasional prenatal controls (p=0.04), as well as smokers (p=0.01), and women preferring a vaginal delivery (p=0.01). The mean STAI S-anxiety score of 43.6+/-4.03 before the cardiotographic examination, increased to 45.2+/-5.4 after this test with a statistically significant difference (p=0.0001). This increase was found to be correlated with the presence of obstetric complications during the current pregnancy (p=0.036) and a lower number of fetal active movements (p=0.029). Based on the EPDS, 22 patients (14.1%) were found to be depressed, but this condition was not correlated with significant increases in anxiety levels., Conclusions: Anxiety levels in pregnant women who undergo routine CTG are increased, and this emotional reaction seems to be influenced by the perception of fetal movement during the examination, and is more evident in pregnancies affected by obstetric complications.
- Published
- 2008
- Full Text
- View/download PDF
6. [Cefamandole nafate in short-term prophylaxis in obstetric and gynecologic surgery].
- Author
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Accardo FM, Mancuso A, Granese D, and Dugo C
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- Adolescent, Adult, Cefamandole analogs & derivatives, Female, Humans, Middle Aged, Postoperative Complications, Bacterial Infections prevention & control, Cefamandole administration & dosage, Cephalosporins administration & dosage, Cesarean Section, Genital Diseases, Female surgery
- Published
- 1983
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