1. Retinal findings of COVID-19 patients using ocular coherence tomography angiography two to three months after infection: Ocular appearance recovered COVID-19 patient
- Author
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Afsaneh, Naderi Beni, Alireza, Dehghani, Farzan, Kianersi, Heshmatollah, Ghanbari, Zahra, Habibidastenae, Seyed Ezatollah, Memarzadeh, and Zahra, Naderi Beni
- Subjects
genetic structures ,OPL, outer plexiform layer ,Optic Disk ,Biophysics ,CDC, the Centers for Disease Control and Prevention ,ICU, inhibitors, intensive care unit ,Dermatology ,optical coherence tomography angiography ,CNS, central nervous system ,RT-PCR, reverse transcription Polymerase Chain Reaction ,Retina ,Article ,VEGFA, Vascular Endothelial Growth Factor A ,DVD, deep vessel density ,VA, Visual acuity ,Humans ,Pharmacology (medical) ,RNFL, retinal nerve fiber layer ,Fluorescein Angiography ,Tomography ,ocular finding retinal finding ,SpO2, oxygen saturation ,OCT, Optical coherence tomography ,INL, the inner nuclear layer ,SARS-CoV-2 ,BCVA, Best-corrected visual acuity ,ILM, internal limiting membrane ,FD, foveal vessel density ,COVID-19 ,Retinal Vessels ,OCTA, Optical coherence tomography angiography ,ACE, Angiotensin-converting enzyme ,DCP, deep capillary plexus ,FAZ, . foveal avascular zone ,GCC, ganglion cell complex ,eye diseases ,SVD, superficial vessel density ,HIF-1, hypoxia-inducible factor 1 ,VD, vessel density ,ONH, Optic Nerve Head ,Cross-Sectional Studies ,Oncology ,SCP, superficial capillary plexus ,Photochemotherapy ,AI, acircularity index ,sense organs ,SSI, signal strength index ,SD, standard deviation ,Tomography, Optical Coherence - Abstract
PURPOSE The aim of this study was to evaluate the ocular disorders in COVID-19 patients, two to three months after infection. METHODS In this cross-sectional, historically controlled study, fifty-one COVID-19 patients were compared with thirty-seven age, and gender-matched healthy individuals. After complete ophthalmological examination, all participants underwent peripapillary and macular optical coherence tomography, and optical coherence tomography angiography (OCTA) measurements (OptoVue Inc, Freemont, CA, USA). RESULTS The time between the initial onset of symptoms, and ophthalmologic examination was 63.31±15.21 (40-95 days). Ophthalmic examination of all the recovered COVID-19 patients was within normal range. None of the peripapillary and macular OCTA parameters were significantly different between the two groups with pairwise comparisons, but after adjusting for age, gender, axial length, and signal strength index (SSI), recovered COVID-19 eyes showed a significant increase in peripapillary retinal nerve fiber (RNFL) thickness, superficial, and deep macular vessel densities in parafoveal and perifoveal regions compared with healthy control eyes (p
- Published
- 2021