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1. Descending Thoracic Aortic Aneurysms

Author

Gallitto, Enrico, Faggioli, Gianluca, Logiacco, Antonino, Caputo, Stefania, Feroldi, Francesca Maria, Sufali, Gemmi, Gargiulo, Mauro, Geroulakos, George, editor, Avgerinos, Efthymios, editor, Becquemin, Jean Pierre, editor, Makris, Gregory C., editor, and Froio, Alberto, editor

Published
2024
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3. An International, Expert-Based Delphi Consensus Document on Controversial Issues about TransCarotid Artery Revascularization (TCAR)

Author

Paraskevas, Kosmas I., AbuRahma, Ali F., Abularrage, Christopher J., Clair, Daniel G., Eldrup-Jorgensen, Jens, Kashyap, Vikram S., Dardik, Alan, de Borst, Gert J., Dermody, Meghan, Faggioli, Gianluca, Hicks, Caitlin W., Kwolek, Christopher J., Lyden, Sean P., Mansilha, Armando, Van Herzeele, Isabelle, Myrcha, Piotr, Leal Lorenzo, Jose Ignacio, Jim, Jeffrey, Pini, Rodolfo, Secemsky, Eric A., Spinelli, Francesco, Capoccia, Laura, Stone, David H., Stoner, Michael C., Zeebregts, Clark J., Lal, Brajesh K., Schneider, Peter A., Malas, Mahmoud B., and Schermerhorn, Marc L.

Published
2025
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5. Urgent endovascular repair of juxtarenal/pararenal aneurysm by off-the-shelf multibranched endograft

Author

Antonello, M., Arzola, H., Austerman, M., Berekoven, B., Bertoglio, L., Bonardelli, S., Bonvini, S., Cappiello, A., Cecere, F., Chiesa, R., Dias, N., Di Marzo, L., D'Oria, M., Faggioli, G., Ferrer, C., Fontaine, V., Freyrie, A., Gallitto, E., Gargiulo, M., Giudice, R., Haulon, S., Isernia, G., Leone, N., Lepidi, S., Mani, K., Mansour, W., Melissano, G., Melloni, A., Melo, R., Mendes Pedro, L., Mezzetto, L., Mitta, N., Nana, P., Oikonou, K., Panuccio, G., Perini, P., Pini, R., Pratesi, G., Pulli, R., Piazza, M., Kahlberg, A., Karelis, A., Katsargyris, A., Kolbel, T., Silingardi, R., Simonte, G., Spath, P., Squizzato, F., Tinelli, G., Torrealba, J., Tsilimparis, N., Wanhainen, A., Vacirca, A., Veraldi, G., Gallitto, Enrico, Faggioli, Gianluca, Austermann, Martin, Kölbel, Tilo, Tsilimparis, Nikolas, Dias, Nuno, Melissano, Germano, Simonte, Gioele, Katsargyris, Athanasios, Oikonomou, Kyriakos, Mani, Kevin, Pedro, Luis Mendes, Cecere, Fabrizio, Haulon, Stephan, and Gargiulo, Mauro

Published
2024
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6. Endograft Thrombosis as an Indication for Open Conversion after Endovascular Aneurysm Repair in a Multicenter Experience over 25 Years

Author

Mersanne, Arianna, Gerosa, Cecilia, Mariani, Erica, Faggioli, Gianluca, Ancetti, Stefano, Migliari, Mattia, Gennai, Stefano, Chisci, Emiliano, Melloni, Andrea, Attisani, Luca, Piffaretti, Gabriele, Mauri, Francesca, Troisi, Nicola, Berchiolli, Raffaella, Fanelli, Mara, Paciaroni, Elisa, Marchetti, Federica, Fornasari, Anna, Perini, Paolo, Gargiulo, Mauro, Silingardi, Roberto, Michelagnoli, Stefano, Bonardelli, Stefano, Bellosta, Raffaello, and Freyrie, Antonio

Published
2024
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7. An international, expert-based, Delphi consensus document on controversial issues in the management of abdominal aortic aneurysms

Author

Paraskevas, Kosmas I., Schermerhorn, Marc L., Haulon, Stephan, Beck, Adam W., Verhagen, Hence J.M., Lee, Jason T., Verhoeven, Eric L.G., Blankensteijn, Jan D., Kölbel, Tilo, Lyden, Sean P., Clair, Daniel G., Faggioli, Gianluca, Bisdas, Theodosios, D'Oria, Mario, Mani, Kevin, Sörelius, Karl, Gallitto, Enrico, Fernandes e Fernandes, Jose, Katsargyris, Athanasios, Lepidi, Sandro, Vacirca, Andrea, Myrcha, Piotr, Koelemay, Mark J.W., Mansilha, Armando, Zeebregts, Clark J., Pini, Rodolfo, Dias, Nuno V., Karelis, Angelos, Bosiers, Michel J., Stone, David H., Venermo, Maarit, Farber, Mark A., Blecha, Matthew, Melissano, Germano, Riambau, Vincent, Eagleton, Matthew J., Gargiulo, Mauro, Scali, Salvatore T., Torsello, Giovanni B., Eskandari, Mark K., Perler, Bruce A., Gloviczki, Peter, Malas, Mahmoud, and Dalman, Ronald L.

Published
2025
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14. Penumbra Indigo Percutaneous Aspiration Thrombectomy System in the treatment of Aortic Endograft Iliac Limb Occlusion: Results from an Italian Multicentre Registry

Author

Spath, Paolo, Angiletta, Domenico, Chegai, Fabrizio, De Donato, Gianmarco, D’Oria, Mario, Faggioli, Gianluca, Gallitto, Enrico, Isernia, Giacomo, Lepidi, Sandro, Migliari, Mattia, Pasqui, Edoardo, Pini, Rodolfo, Silingardi, Roberto, Simonte, Gioele, Spinazzola, Angelo, Gargiulo, Mauro, and de Donato, Gianmarco

Published
2023
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17. Why do guidelines recommend screening for abdominal aortic aneurysms, but not for asymptomatic carotid stenosis? A plea for a randomized controlled trial

Author

Paraskevas, Kosmas I., Spence, J. David, Mikhailidis, Dimitri P., Antignani, Pier Luigi, Gloviczki, Peter, Eckstein, Hans-Henning, Spinelli, Francesco, Stilo, Francesco, Saba, Luca, Poredos, Pavel, Dardik, Alan, Liapis, Christos D., Mansilha, Armando, Faggioli, Gianluca, Pini, Rodolfo, Jezovnik, Mateja K., Sultan, Sherif, Musiałek, Piotr, Goudot, Guillaume, Lavenson, George S., Jr, Jawien, Arkadiusz, Blinc, Aleš, Myrcha, Piotr, Fernandes e Fernandes, Jose, Geroulakos, George, Kakkos, Stavros K., Knoflach, Michael, Proczka, Robert M., Capoccia, Laura, Rundek, Tatjana, Svetlikov, Alexei S., Silvestrini, Mauro, Ricco, Jean-Baptiste, Davies, Alun H., Di Lazzaro, Vincenzo, Suri, Jasjit S., Lanza, Gaetano, Fraedrich, Gustav, Zeebregts, Clark J., and Nicolaides, Andrew N.

Published
2023
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18. Outcomes of Elective and non-elective fenestrated-branched Endovascular Aortic Repair for Treatment of Thoracoabdominal Aortic Aneurysms

Author

Dias-Neto, Marina, Vacirca, Andrea, Huang, Ying, Baghbani-Oskouei, Aidin, Jakimowicz, Tomasz, Mendes, Bernardo C., Kolbel, Tilo, Sobocinski, Jonathan, Bertoglio, Luca, Mees, Barend, Gargiulo, Mauro, Dias, Nuno, Schanzer, Andres, Gasper, Warren, Beck, Adam W., Farber, Mark A., Mani, Kevin, Timaran, Carlos, Schneider, Darren B., Pedro, Luis Mendes, Tsilimparis, Nikolaos, Haulon, Stéphan, Sweet, Matthew P., Ferreira, Emília, Eagleton, Matthew, Yeung, Kak Khee, Khashram, Manar, Jama, Katarzyna, Panuccio, Giuseppe, Rohlffs, Fiona, Mesnard, Thomas, Chiesa, Roberto, Kahlberg, Andrea, Schurink, Geert Willem, Lemmens, Charlotte, Gallitto, Enrico, Faggioli, Gianluca, Karelis, Angelos, Parodi, Ezequiel, Gomes, Vivian, Wanhainen, Anders, Habib, Mohammed, Colon, Jesus Porras, Pavarino, Felipe, Baig, Mirza S., Gouveia e Melo, Ryan Eduardo Costeloe De, Crawford, Sean, Zettervall, Sara L., Garcia, Rita, Ribeiro, Tiago, Alves, Gonçalo, Gonçalves, Frederico Bastos, Kappe, Kaj Olav, Mariko van Knippenberg, Samira Elize, Tran, Bich Lan, Gormley, Sinead, and Oderich, Gustavo S.

Published
2023
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19. Fenestrated and Branched Endografts for Post-Dissection Thoraco-Abdominal Aneurysms: Results of a National Multicentre Study and Literature Review

Author

Luca, Bertoglio, Roberto, Chiesa, Gianluca, Faggioli, Aaron, Fargion, Cecilia, Fenelli, Enrico, Gallitto, Mauro, Gargiulo, Giacomo, Isernia, Massimo, Lenti, Antonino, Logiacco, Chiara, Mascoli, Germano, Melissano, Rodolfo, Pini, Carlo, Pratesi, Andrea, Kahlberg, Gioele, Simonte, Paolo, Spath, Sara, Speziali, Gallitto, Enrico, Faggioli, Gianluca, Melissano, Germano, Fargion, Aaron, Isernia, Giacomo, Bertoglio, Luca, Simonte, Gioele, Lenti, Massimo, Pratesi, Carlo, Chiesa, Roberto, and Gargiulo, Mauro

Published
2022
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20. Optimal periprocedural antithrombotic treatment in carotid interventions: An international, multispecialty, expert review and position statement

Author

Paraskevas, Kosmas I., Gloviczki, Peter, Mikhailidis, Dimitri P., Antignani, Pier Luigi, Dardik, Alan, Eckstein, Hans-Henning, Faggioli, Gianluca, Fernandes e Fernandes, Jose, Fraedrich, Gustav, Gupta, Ajay, Jawien, Arkadiusz, Jezovnik, Mateja K., Kakkos, Stavros K., Knoflach, Michael, Lal, Brajesh K., Lanza, Gaetano, Liapis, Christos D., Loftus, Ian M., Mansilha, Armando, Millon, Antoine, Pini, Rodolfo, Poredos, Pavel, Proczka, Robert M., Ricco, Jean-Baptiste, Rundek, Tatjana, Saba, Luca, Schlachetzki, Felix, Silvestrini, Mauro, Spinelli, Francesco, Stilo, Francesco, Suri, Jasjit S., Zeebregts, Clark J., Lavie, Carl J., and Chaturvedi, Seemant

Published
2022
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22. Benefits and drawbacks of statins and non-statin lipid lowering agents in carotid artery disease

Author

Paraskevas, Kosmas I., Gloviczki, Peter, Antignani, Pier Luigi, Comerota, Anthony J., Dardik, Alan, Davies, Alun H., Eckstein, Hans-Henning, Faggioli, Gianluca, Fernandes e Fernandes, Jose, Fraedrich, Gustav, Geroulakos, George, Golledge, Jonathan, Gupta, Ajay, Gurevich, Victor S., Jawien, Arkadiusz, Jezovnik, Mateja K., Kakkos, Stavros K., Knoflach, Michael, Lanza, Gaetano, Liapis, Christos D., Loftus, Ian M., Mansilha, Armando, Nicolaides, Andrew N., Pini, Rodolfo, Poredos, Pavel, Proczka, Robert M., Ricco, Jean-Baptiste, Rundek, Tatjana, Saba, Luca, Schlachetzki, Felix, Silvestrini, Mauro, Spinelli, Francesco, Stilo, Francesco, Suri, Jasjit S., Svetlikov, Alexei V., Zeebregts, Clark J., Chaturvedi, Seemant, Veith, Frank J., and Mikhailidis, Dimitri P.

Published
2022
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24. Twenty-Five Year Multicentre Experience of Explantation of Infected Abdominal Aortic Endografts.

Author

Perini, Paolo, Gargiulo, Mauro, Silingardi, Roberto, Bonardelli, Stefano, Bellosta, Raffaello, Piffaretti, Gabriele, Michelagnoli, Stefano, Ferrari, Mauro, Turicchia, Giorgio Ubaldo, Freyrie, Antonio, Fornasari, Anna, Mariani, Erica, Faggioli, GianLuca, Spath, Paolo, Migliari, Mattia, Gennai, Stefano, Paro, Barbara, Baggi, Paolo, Attisani, Luca, and Pegorer, Matteo

Subjects
AORTA surgery, KIDNEY failure, PROSTHESIS-related infections, ENDOVASCULAR aneurysm repair, HOSPITAL care, RESPIRATORY insufficiency, BLOOD vessel prosthesis, RETROSPECTIVE studies, TREATMENT effectiveness, HOSPITAL mortality, DESCRIPTIVE statistics, VASCULAR surgery, SURGICAL complications, LOG-rank test, ABDOMINAL aortic aneurysms, RESEARCH, HEALTH facilities, PLASTIC surgery, PATIENT aftercare, TIME, DISEASE risk factors, SYMPTOMS
Abstract

We report a multicenter experience of open conversions (OC) for aortic endograft infections (AEI). We retrospectively analyzed all patients who underwent OC for AEI after endovascular aneurysm repair (EVAR), from 1997 to 2021 in 12 Italian centers. The endpoints were as follows: mortality (30-days, in-hospital), major postoperative complications. Follow-up data included: survival, aortic-related complications, infection persistence or reoccurrence. Fifty-eight patients (mean age: 73.8 ± 6.6 years) were included. Median time from EVAR to OC was 14 months (interquartile range 7–45). Thirty-five patients (60.3%) were symptomatic at presentation. Aortic reconstruction was anatomic in 32 patients (55.2%), extra-anatomic in 26 (44.8%). Thirty-day mortality was 31% (18/58). Six additional patients died after 30 days during the same hospitalization (in-hospital mortality: 41.4%). Most common post-operative complications included respiratory failure (38.6%) and renal insufficiency (35.1%). During 28.1 ± 4 months follow-up, 4 aneurysm-related deaths were recorded. Infection re-occurred in 29.4% of the patients. Estimated survival was 50% at 1 year, and 30% at 5 years, and was significantly lower for patients who underwent extra-anatomic reconstructions (37 vs 61% at 1 year, 16 vs 45% at 5 years; log-rank P =.021). OC for AEI is associated with high early mortality. The poor mid-term survival is influenced by aortic complications and infection re-occurrence. [ABSTRACT FROM AUTHOR]

Published
2025
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25. Renal Benefits of CO2 as a Contrast Media for EVAR Procedures: New Perspectives on 1 Year Outcomes.

Author

Busutti, Marco, Sensoni, Alice, Vacirca, Andrea, Abenavoli, Chiara, Donadei, Chiara, Croci Chiocchini, Anna Laura, Righini, Matteo, Comai, Giorgia, Pini, Alessia, Faggioli, Gianluca, Gallitto, Enrico, La Manna, Gaetano, and Gargiulo, Mauro

Abstract

Background and Objectives: Endovascular aneurism repair (EVAR) is a minimally invasive alternative to open surgery for the treatment of abdominal aortic aneurysm. Iodine contrast medium (ICM) is considered the gold standard, at the high price of related nephrotoxicity and allergic reactions. Carbon dioxide (CO2) has been suggested as an alternative non-nephrotoxic contrast media agent. We aimed to evaluate the safety and the renal impact of the administration of CO2, compared with ICM in EVAR procedures. Design, Setting, Participants, and Measurements: We retrospectively reviewed data of patients who underwent EVAR at the Vascular Surgery Department of the Sant'Orsola Hospital in Bologna. Estimated glomerular filtration rate (eGFR) was evaluated before intervention, immediately after and at 12 months. Results: In total, 22 patients received CO2 and low-dose ICM (CO2 Group) and 22 received standard ICM (Control Group), matched for clinical characteristics and renal function at the time of procedure. Pre and post-operative renal function values (eGFR) were compared between the two groups: in the immediate post-operative the group treated with CO2 and low-dose ICM globally showed a slight improvement in renal function (mean eGFR +5.10%±3.2), meanwhile the group treated with standard dose of ICM presented a significant worsening of renal function compared with pre-procedure values (mean eGFR −9.65%±4). Incidence of post-contrast acute kidney injury (PC-AKI) was 9% in the CO2 group vs 27% in the Control group. At 12 months, the renal impairment was significantly greater in the ICM group than in the CO2 group (mean eGFR decrease −19.2%±11.1 and −7.40%±3.5, respectively). Conclusions: Administration of either CO2 alone or along with low-dose ICM showed to be safer than full-dose ICM alone, lowering the incidence of PC-AKI in patients undergoing EVAR. Unexpectedly, our study revealed also a significant worsening of renal function in patients treated with standard dose of ICM in 1-year follow-up, introducing the concept that acute renal damage caused by ICM could elicit a chronic injury process that affect long-term renal outcomes. Clinical Impact: Evaluating the safety and the renal impact of the administration of CO2, compared to Iodinate Contrast Medium, in EVAR procedures represents a first step in order to further tayloring medical procedures on patients characteristics. Our findings can guide the clinicians and surgeons in the procedures choice, not considering only the immediate effect of ICM on renal function but also the potential long-term effects. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Morphological and Clinical Predictors of Early/Follow-up Failure of the Endovascular Infrarenal Abdominal Aneurysm Repair With Currently Available Endografts.

Author

Gallitto, Enrico, Faggioli, Gianluca, Mascoli, Chiara, Goretti, Martina, Pini, Rodolfo, Logiacco, Antonino, Rocchi, Cristina, Feroldi, Francesca, Caputo, Stefania, and Gargiulo, Mauro

Abstract

Purpose: To report outcomes of endovascular repair (EVAR) of infrarenal abdominal aortic aneurysms (AAAs) with currently-available endografts and identify predictors of technical/clinical failure. Materials and Methods: Patients undergoing EVAR between 2012 and 2020 were prospectively collected and retrospectively analyzed. Technical success (TS: no type I–III endoleaks, renal/hypogastric arteries loss, iliac leg occlusion, conversion to open repair and mortality within 24 postoperative hour), proximal neck–related TS (nr-TS: no proximal type I endoleaks, unplanned renal arteries coverage), and 30-day mortality were assessed as early outcomes. Proximal type I endoleak (ELIa), survival and freedom from reinterventions (FFRs) were assessed during follow-up. Uni/multivariate analysis and Cox-regression were used to identified factors associated with early and follow-up outcomes; FFR and survival were assessed by Kaplan-Meier analysis. Results: A total of 710 were included. Technical success and nr-TS were 692 (98%) and 700 (99%), respectively. The presence of ≥2 hostile anatomical infrarenal neck characteristics was associated with technical failure (odds ratio [OR]: 2.4; 95% confidence interval [CI]: 1.3–4.1; p: 0.007). Infrarenal neck angle >90° (OR: 2.88; 95% CI: 9.6–50.3; p: 0.004), barrel shape (OR: 2.33; 95% CI: 11.1–100.3; p: 0.02) or presence of ≥2 hostile anatomical infrarenal neck characteristics (OR: 2.16; 95% CI: 2.5–5.3; p: 0.03) were independent risk factors for neck-related technical failures. Six (0.8%) patients died within 30 postoperative days. Chronic obstructive pulmonary disease (OR: 16; 95% CI: 1.1–218.3; p: 0.04) and urgent repair (OR: 15; 95% CI: 1.8–119.6; p: 0.01) were independent risk factors for 30-day mortality. The mean follow-up was 53±13 months. There were 12 (1.7%) ELIa during follow-up. Infrarenal neck length <15 mm (hazard ratio [HR]: 2.8; 95% CI: 1.9–9.6; p: 0.005), diameter >28 mm (HR: 2.7; 95% CI: 1.6–9.5; p: 0.006), angle ≥90° (HR: 2.7; 95% CI: 8.3–50.1; p: 0.007), and persistent type II endoleak (HR: 2.9; 95% CI: 1.6–10.1; p: 0.004) were independent risk factors for ELIa. Freedom from reintervention was 91% at 5 years. The ELIa was an independent risk factor for reinterventions during follow-up (HR: 29.5; 95% CI: 1.4–1.6; p<0.001). Survival was 74% at 5 years with 2 cases (0.3%) of late aortic-related mortality. Peripheral arterial occlusive disease (HR: 1.9; 95% CI: 1.4–3.65; p: 0.03), aneurysm diameter ≥65 mm (HR: 2.2; 95% CI: 1.4–3.26; p<0.001), and infrarenal neck length <15 mm (HR: 1.7; 95% CI: 1.2–2.35; p: 0.04) were independent risk factors for mortality during follow-up. Conclusion: Endovascular repair with currently-available endografts has high TS and low 30-day mortality. Survival and FFRs were satisfactory at mid-term. Pre/postoperative risk factors for technical and clinical failure were identified and they should be considered in EVAR indication and postoperative management to reduce complications and improve mid-term outcome. Clinical Impact: Pre and postoperative risk factors for technical and clinical EVAR failure can be identified and they should be considered in EVAR indication and postoperative management to reduce complications and improve mid-term outcome. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Urgent endovascular repair of juxtarenal/pararenal aneurysm by off-the-shelf multibranched endograft.

Author

Gallitto, Enrico, Faggioli, Gianluca, Austermann, Martin, Kölbel, Tilo, Tsilimparis, Nikolas, Dias, Nuno, Melissano, Germano, Simonte, Gioele, Katsargyris, Athanasios, Oikonomou, Kyriakos, Mani, Kevin, Pedro, Luis Mendes, Cecere, Fabrizio, Haulon, Stephan, and Gargiulo, Mauro

Abstract

To report outcomes of urgent juxtarenal/pararenal aneurysms (J/P-AAAs) managed by off-the-shelf multibranched thoracoabdominal endografts (Cook, T-branch). In this observational, multicenter, retrospective study, patients with J/P-AAAs treated by urgent endovascular repair by T-branch in 23 European aortic centers, from 2013 to 2023, were analyzed. Contained J/P-AAAs rupture, presence of related symptoms, and aneurysm diameter of >70 mm were considered as indication for urgent repair. Technical success (TS), spinal cord ischemia (SCI), and 30-day/hospital mortality were assessed as early outcomes. Survival, freedom from reinterventions, and target artery instability (TAI) were evaluated during follow-up. Overall, 197 patients (J-AAAs, n = 64 [33%]; P-AAAs, n = 95 [48%]; previous failed endovascular aneurysm repair (EVAR), n = 38 [19%]) were analyzed. The mean age and aneurysm diameter was 75 ± 8 years and 76 ± 4 mm, respectively. The American Society of Anesthesiologists score was 3 and 4 in 118 (60%) and 79 (40%) patients. Rupture, symptoms, and diameter of >70 mm were present in 51 (26%), 110 (56%), and 53 (27%) patients, respectively. An adjunctive proximal thoracic endograft was used in 28 cases (14%). The mean aortic coverage between the upper portion of the endograft and the lowest renal artery was 154 ± 49 mm. Single-stage repair and cerebrospinal fluid drainage were reported in 144 (73%) and 53 (27%) cases, respectively. TS was achieved in 182 (92%) cases (rupture, 84% vs no rupture, 95%; P =.02). Failures consist of TA loss (11 [6%]: renal artery, 9; celiac trunk, 2), type I to III endoleaks (2 [1%]), and 24-h mortality (2 [1%]). Rupture was a risk factor for technical failure (P =.02; odds ratio [OR], 3.8; 95% confidence interval [CI], 1.1-12.1). Overall, 15 patients (8%) had persistent SCI (rupture, 14% vs no rupture, 5%) with 11 (6%) , of paraplegia (rupture, 10% vs no rupture, 5%; P =.001). Rupture (P =.04; OR, 3.1; 95% CI, 1.1-8.9) and adjunctive proximal thoracic endograft (P =.01; OR, 4.1; 95% CI, 1.3-12.9) were risk-factors for SCI. Twenty-two patients (11%) died within 30 days or during a prolonged hospitalization. Previous failed EVAR (P =.04; OR, 3.6; 95% CI, 1.1-12.3), paraplegia (P <.001; OR, 9.9; 95% CI, 1.6-62.2) and postoperative mesenteric complications (P =.03; OR, 10.4; 95% CI, 1.2-93.3), as well as cardiac (P =.03; OR, 8.2; 95% CI, 2.0-33.0) and respiratory (P <.001; OR, 10.1; 95% CI, 2.9-35.2) morbidities were associated with 30-day/hospital mortality. The mean follow-up was 19 ± 5 months. The estimated 3-year survival and freedom from reinterventions was 58% and 77%, respectively. TAI occurred in 27 patients (14%) (occlusion, 15; endoleak, 14) with an estimated 3-year freedom from TAI of 72%. Urgent repair of J/P-AAAs by T-branch is feasible and effective with satisfactory TS and 30-day/hospital mortality in high-risk patients. However, extensive aortic coverage is necessary, leading to a non-negligible SCI rate, especially in case of aortic rupture or when adjunctive thoracic endografts are necessary. Previous failed EVAR and postoperative mesenteric complications, as well as cardiac and respiratory morbidities were associated with 30-day/hospital mortality and should be subjected to more research for the purposes of improving outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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28. The impact of large aneurysm diameter on the outcomes of thoracoabdominal aneurysm repair by fenestrated and branched endografts.

Author

Gallitto, Enrico, Tsilimparis, Nikolaos, Spath, Paolo, Faggioli, Gianluca, Stana, Jan, Logiacco, Antonino, Fernandez-Prendes, Carlota, Pini, Rodolfo, Rantner, Barbara, Mascoli, Chiara, Cappiello, Antonio, and Gargiulo, Mauro

Subjects
THORACOABDOMINAL aortic aneurysms, ABDOMINAL aortic aneurysms, ENDOVASCULAR aneurysm repair, ENDOVASCULAR surgery, PREOPERATIVE care
Abstract

OBJECTIVES Aim of the study was to analyse the impact of preoperative thoracoabdominal aneurysm diameter on the outcomes of fenestrated/branched endografting. METHODS Patients who underwent endovascular thoracoabdominal repair at 2 European centres (2011–2021) were analysed. Median diameter was calculated; the third quartile was considered a cut-off. Outcomes were compared in 2 groups based on the diameter value. Primary endpoints were technical success, spinal cord ischaemia and 30-day/in-hospital mortality. Survival, freedom from reintervention and target visceral vessels instability were follow-up outcomes. RESULTS Out of 247 thoracoabdominal aortic aneurysms, the median diameter was 65 mm, first quartile was 57 mm; third quartile was 80 mm, set as cut-off value. Fifty-nine (24%) patients had diameter ≥80 mm. Custom-made and off-the-shelf branched endograft were used in 160 (65%) and 87 (35%), respectively. Technical success was 93% (<80 mm: 91% vs ≥80 mm: 94%; P = 0.47). Twenty-three (9%) patients had spinal injury (<80 mm: 7% vs ≥80mm: 17%; P = 0.03). Twenty-two (9%) patients died within 30-day/in-hospital (<80 mm: 7% vs ≥80 mm: 15%; P = 0.06). Multivariate analysis did not report preoperative diameter ≥80 mm as significant risk factor for primary endpoints. The median follow-up was 13 (interquartile range: 2–37) months and at 3-year survival and freedom from reintervention rates were 65% and 62%, respectively. After univariate and multivariate analyses, preoperative diameter ≥80 mm was considered an independent risk factor for reinterventions [hazard ratio (HR): 1.9; 95% confidence interval (CI) 1.1–3.6; P = 0.04], and for target visceral vessels instability (HR: 3.1; 95% CI: 1.3–5.1; P = 0.04), occurred in 45 (18%) cases. However, after competing risk methods, preoperative diameter did not show significance for follow-up results. CONCLUSIONS A preoperative thoracoabdominal aortic aneurysm diameter >80 mm has not had a direct impact on early technical and clinical outcomes. A diameter≥80 mm is considered risk factor for reinterventions and target vessels instability is considered separately during follow-up. [ABSTRACT FROM AUTHOR]

Published
2024
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32. Optimal Management of Asymptomatic Carotid Stenosis in 2021: The Jury is Still Out. An International, Multispecialty, Expert Review and Position Statement

Author

Paraskevas, Kosmas I., Mikhailidis, Dimitri P., Antignani, Pier Luigi, Baradaran, Hediyeh, Bokkers, Reinoud P.H., Cambria, Richard P., Dardik, Alan, Davies, Alun H., Eckstein, Hans-Henning, Faggioli, Gianluca, e Fernandes, Jose Fernandes, Fraedrich, Gustav, Geroulakos, George, Gloviczki, Peter, Golledge, Jonathan, Gupta, Ajay, Jezovnik, Mateja K., Kakkos, Stavros K., Katsiki, Niki, Knoflach, Michael, Kooi, M. Eline, Lanza, Gaetano, Liapis, Christos D., Loftus, Ian M., Mansilha, Armando, Millon, Antoine, Nicolaides, Andrew N., Pini, Rodolfo, Poredos, Pavel, Ricco, Jean-Baptiste, Riles, Thomas S., Ringleb, Peter Arthur, Rundek, Tatjana, Saba, Luca, Schlachetzki, Felix, Silvestrini, Mauro, Spinelli, Francesco, Stilo, Francesco, Sultan, Sherif, Suri, Jasjit S., Zeebregts, Clark J., and Chaturvedi, Seemant

Published
2022
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33. Anesthetic management of carotid endarterectomy: an update from Italian guidelines

Author

Bevilacqua, Sergio, Ticozzelli, Giulia, Orso, Massimiliano, Alba, Giuseppe, Capoccia, Laura, Cappelli, Alessandro, Cernetti, Carlo, Diomedi, Marina, Dorigo, Walter, Faggioli, Gianluca, Giannace, Giovanni, Giannandrea, David, Giannetta, Matteo, Lessiani, Gianfranco, Marone, Enrico Maria, Mazzaccaro, Daniela, Migliacci, Rino, Nano, Giovanni, Pagliariccio, Gabriele, Petruzzellis, Marco, Plutino, Andrea, Pomatto, Sara, Pulli, Raffaele, Sirignano, Pasqualino, Vacirca, Andrea, Visco, Emanuele, Moghadam, Shadeh Parsapour, Lanza, Gaetano, and Lanza, Jessica

Published
2022
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36. Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy

Author

Halliday, Alison, Bulbulia, Richard, Bonati, Leo H, Peto, Richard, Pan, Hongchao, Potter, John, Henning Eckstein, Hans, Farrell, Barbara, Flather, Marcus, Mansfield, Averil, Mihaylova, Boby, Rahimi, Kazim, Simpson, David, Thomas, Dafydd, Sandercock, Peter, Gray, Richard, Molyneux, Andrew, Shearman, Cliff P, Rothwell, Peter, Belli, Anna, Herrington, Will, Judge, Parminder, Leopold, Peter, Mafham, Marion, Gough, Michael, Cao, Piergiorgio, MacDonald, Sumaira, Bari, Vasha, Berry, Clive, Bradshaw, S, Brudlo, Wojciech, Clarke, Alison, Chester, Johanna, Cox, Robin, Cradduck-Bamford, Andrea, Fathers, Susan, Gaba, Kamran, Gray, Mo, Hayter, Elizabeth, Holliday, Constance, Kurien, Rijo, Lay, Michael, le Conte, Steffi, McManus, Jessica, Madgwick, Zahra, Morris, Dylan, Munday, Andrew, Pickworth, Sandra, Ostasz, Wiktor, Poorthuis, Michiel, Richards, Sue, Teixeira, Louisa, Tochlin, Sergey, Tully, Lynda, Wallis, Carol, Willet, Monique, Young, Alan, Casana, Renato, Malloggi, Chiara, Odero Jr, Andrea, Silani, Vincenzo, Parati, Gianfranco, Malchiodi, Giuseppe, Malferrari, Giovanni, Strozzi, Francesco, Tusini, Nicola, Vecchiati, Enrico, Coppi, Gioacchino, Lauricella, Antonio, Moratto, Roberto, Silingardi, Roberto, Veronesi, Jessica, Zini, Andrea, Ferrero, Emanuele, Ferri, Michelangelo, Gaggiano, Andrea, Labate, Carmelo, Nessi, Franco, Psacharopulo, Daniele, Viazzo, Andrea, Malacrida, Giovanni, Mazzaccaro, Daniela, Meola, Giovanni, Modafferi, Alfredo, Nano, Giovanni, Occhiuto, Maria Teresa, Righini, Paolo, Stegher, Silvia, Chiarandini, Stefano, Griselli, Filippo, Lepidi, Sandro, Pozzi Mucelli, Fabio, Naccarato, Marcello, D'Oria, Mario, Ziani, Barbara, Stella, Andrea, Dieng, Mortalla, Faggioli, Gianluca, Gargiulo, Mauro, Palermo, Sergio, Pini, Rodolfo, Puddu, Giovanni Maria, Vacirca, Andrea, Angiletta, Domenico, Desantis, Claudio, Marinazzo, Davide, Mastrangelo, Giovanni, Regina, Guido, Pulli, Raffaele, Bianchi, Paolo, Cireni, Lea, Coppi, Elisabetta, Pizzirusso, Rocco, Scalise, Filippo, Sorropago, Giovanni, Tolva, Valerio, Caso, Valeria, Cieri, Enrico, DeRango, Paola, Farchioni, Luca, Isernia, Giacomo, Lenti, Massimo, Parlani, Gian Battista, Pupo, Guglielmo, Pula, Grazia, Simonte, Gioele, Verzini, Fabio, Carimati, Federico, Delodovici, Maria Luisa, Fontana, Federico, Piffaretti, Gabriele, Tozzi, Matteo, Civilini, Efrem, Poletto, Giorgio, Reimers, Bernhard, Praquin, Barbara, Ronchey, Sonia, Capoccia, Laura, Mansour, Wassim, Sbarigia, Enrico, Speziale, Francesco, Sirignano, Pasqualino, Toni, Danilo, Galeotti, Roberto, Gasbarro, Vincenzo, Mascoli, Francesco, Rocca, Tiberio, Tsolaki, Elpiniki, Bernardini, Giulia, DeMarco, Ester, Giaquinta, Alessia, Patti, Francesco, Veroux, Massimiliano, Veroux, Pierfrancesco, Virgilio, Carla, Mangialardi, Nicola, Orrico, Matteo, Di Lazzaro, Vincenzo, Montelione, Nunzio, Spinelli, Francesco, Stilo, Francesco, Cernetti, Carlo, Irsara, Sandro, Maccarrone, Giuseppe, Tonello, Diego, Visonà, Adriana, Zalunardo, Beniamino, Chisci, Emiliano, Michelagnoli, Stefano, Troisi, Nicola, Masato, Maela, Dei Negri, Massimo, Pacchioni, Andrea, Saccà, Salvatore, Amatucci, Giovanni, Cannizzaro, Alfredo, Accrocca, Federico, Ambrogi, Cesare, Barbazza, Renzo, Marcucci, Giustino, Siani, Andrea, Bajardi, Guido, Savettieri, Giovanni, Argentieri, Angelo, Corbetta, Riccardo, Odero, Attilio, Quaretti, Pietro, Thyrion, Federico Z, Cappelli, Alessandro, Benevento, Domenico, De Donato, Gianmarco, Mele, Maria Agnese, Palasciano, Giancarlo, Pieragalli, Daniela, Rossi, Alessandro, Setacci, Carlo, Setacci, Francesco, Palombo, Domenico, Perfumo, Maria Cecilia, Martelli, Edoardo, Paolucci, Aldo, Trimarchi, Santi, Grassi, Viviana, Grimaldi, Luigi, La Rosa, Giuliana, Mirabella, Domenico, Scialabba, Matteo, Sichel, Leonildo, D'Angelo, Costantino L, Fadda, Gian Franco, Kasemi, Holta, Marino, Mario, Burzotta, Francesco, Codispoti, Francesco Alberto, Ferrante, Angela, Tinelli, Giovanni, Tshomba, Yamume, Vincenzoni, Claudio, Amis, Deborah, Anderson, Dawn, Catterson, Martin, Clarke, Mike, Davis, Michelle, Dixit, Anand, Dyker, Alexander, Ford, Gary, Jackson, Ralph, Kappadath, Sreevalsan, Lambert, David, Lees, Tim, Louw, Stephen, McCaslin, James, Parr, Noala, Robson, Rebecca, Stansby, Gerard, Wales, Lucy, Wealleans, Vera, Wilson, Lesley, Wyatt, Michael, Baht, Hardeep, Balogun, Ibrahim, Burger, Ilse, Cosier, Tracy, Cowie, Linda, Gunathilagan, Gunaratnam, Hargroves, David, Insall, Robert, Jones, Sally, Rudenko, Hannah, Schumacher, Natasha, Senaratne, Jawaharlal, Thomas, George, Thomson, Audrey, Webb, Tom, Brown, Ellen, Esisi, Bernard, Mehrzad, Ali, MacSweeney, Shane, McConachie, Norman, Southam, Alison, Sunman, Wayne, Abdul-Hamiq, Ahmed, Bryce, Jenny, Chetter, Ian, Ettles, Duncan, Lakshminarayan, Raghuram, Mitchelson, Kim, Rhymes, Christopher, Robinson, Graham, Scott, Paul, Vickers, Alison, Ashleigh, Ray, Butterfield, Stephen, Gamble, Ed, Ghosh, Jonathan, McCollum, Charles N, Welch, Mark, Welsh, Sarah, Wolowczyk, Leszek, Donnelly, Mary, D'Souza, Stephen, Egun, Anselm A, Gregary, Bindu, Joseph, Thomas, Kelly, Christine, Punekar, Shuja, Rahi, M Asad, Raj, Sonia, Seriki, Dare, Thomson, George, Brown, James, Durairajan, Ragunath, Grunwald, Iris, Guyler, Paul, Harman, Paula, Jakeways, Matthew, Khuoge, Christopher, Kundu, Ashish, Loganathan, Thayalini, Menon, Nisha, Prabakaran, Raji O, Sinha, Devesh, Thompson, Vicky, Tysoe, Sharon, Briley, Dennis, Darby, Chris, Hands, Linda, Howard, Dominic, Kuker, Wilhelm, Schulz, Ursula, Teal, Rachel, Barer, David, Brown, Andrew, Crawford, Susan, Dunlop, Paul, Krishnamurthy, Ramesh, Majmudar, Nikhil, Mitchell, Duncan, Myint, Min P, O'Brien, Richard, O'Connell, Janice, Sattar, Naweed, Vetrivel, Shanmugam, Beard, Jonathan, Cleveland, Trevor, Gaines, Peter, Humphreys, John, Jenkins, Alison, King, Craig, Kusuma, Daniel, Lindert, Ralph, Lonsdale, Robbie, Nair, Raj, Nawaz, Shah, Okhuoya, Faith, Turner, Douglas, Venables, Graham, Dorman, Paul, Hughes, Andrea, Jones, Deborah, Mendelow, David, Rodgers, Helen, Raudoniitis, Aidas, Enevoldson, Peter, Nahser, Hans, O'Brien, Imelda, Torella, Francesco, Watling, Dave, White, Richard, Brown, Pauline, Dutta, Dipankar, Emerson, Lorraine, Hilltout, Paula, Kulkarni, Sachin, Morrison, Jackie, Poskitt, Keith, Slim, Fiona, Smith, Sarah, Tyler, Amanda, Waldron, Joanne, Whyman, Mark, Bajoriene, Milda, Baker, Lucy, Colston, Amanda, Eliot-Jones, Bekky, Gramizadeh, Gita, Lewis-Clarke, Catherine, McCafferty, Laura, Oliver, Deborah, Palmer, Debbie, Patil, Abhijeet, Pegler, Suzannah, Ramadurai, Gopi, Roberts, Aisling, Sargent, Tracey, Siddegowda, Shivaprasad, Singh-Ranger, Ravi, Williams, Akintunde, Williams, Lucy, Windebank, Steve, Zuromskis, Tadas, Alwis, Lanka, Angus, Jane, Asokanathan, Asaipillai, Fornolles, Caroline, Hardy, Diana, Hunte, Sophy, Justin, Frances, Phiri, Duke, Mitabouana-Kibou, Marie, Sekaran, Lakshmanan, Sethuraman, Sakthivel, Tate, Margaret L, Akyea-Mensah, Joyce, Ball, Stephen, Chrisopoulou, Angela, Keene, Elizabeth, Phair, Alison, Rogers, Steven, Smyth, John V, Bicknell, Colin, Chataway, Jeremy, Cheshire, Nicholas, Clifton, Andrew, Eley, Caroline, Gibbs, Richard, Hamady, Mohammad, Hazel, Beth, James, Alex, Jenkins, Michael, Khanom, Nyma, Lacey, Austin, Mireskandari, Maz, O'Reilly, Joanna, Pereira, Antony, Sachs, Tina, Wolfe, John, Davey, Philip, Rogers, Gill, Smith, Gemma, Tervit, Gareth, Nichol, Ian, Parry, Andrew, Young, Gavin, Ashley, Simon, Barwell, James, Dix, Francis, Nor, Azlisham M, Parry, Chris, Birt, Angela, Davies, Paul, George, Jim, Graham, Anne, Jonker, Leon, Kelsall, Nicci, Potts, Caroline, Wilson, Toni, Crinnion, Jamie, Cuenoud, Larissa, Aleksic, Nikola, Babic, Srdan, Ilijevski, Nenad, Radak, Đorde, Sagic, Dragan, Tanaskovic, Slobodan, Colic, Momcilo, Cvetic, Vladimir, Davidovic, Lazar, Jovanovic, Dejana R, Koncar, Igor, Mutavdžic, Perica, Sladojevic, Miloš, Tomic, Ivan, Debus, Eike S, Grzyska, Ulrich, Otto, Dagmar, Thomalla, Götz, Barlinn, Jessica, Gerber, Johannes, Haase, Kathrin, Hartmann, Christian, Ludwig, Stefan, Pütz, Volker, Reeps, Christian, Schmidt, Christine, Weiss, Norbert, Werth, Sebastian, Winzer, Simon, Gemper, Janine, Günther, Albrecht, Heiling, Bianka, Jochmann, Elisabeth, Karvouniari, Panagiota, Klingner, Carsten, Mayer, Thomas, Schubert, Julia, Schulze-Hartung, Friederike, Zanow, Jürgen, Bausback, Yvonne, Borger, Franka, Botsios, Spiridon, Branzan, Daniela, Bräunlich, Sven, Hölzer, Henryk, Lenzer, Janin, Piorkowski, Christopher, Richter, Nadine, Schuster, Johannes, Scheinert, Dierk, Schmidt, Andrej, Staab, Holger, Ulrich, Matthias, Werner, Martin, Berger, Hermann, Biró, Gábor, Eckstein, Hans-Henning, Kallmayer, Michael, Kreiser, Kornelia, Zimmermann, Alexander, Berekoven, Bärbel, Frerker, Klaus, Gordon, Vera, Torsello, Giovanni, Arnold, Sebastian, Dienel, Cora, Storck, Martin, Biermaier, Bernhard, Gissler, Hans Martin, Klötzsch, Christof, Pfeiffer, Tomas, Schneider, Ralph, Söhl, Leander, Wennrich, Michael, Alonso, Angelika, Keese, Michael, Groden, Christoph, Cöster, Andreas, Engelhardt, Andreas, Ratusinski, Christoph-Maria, Berg, Bengt, Delle, Martin, Formgren, Johan, Gillgren, Peter, Jarl, Lotta, Kall, Torbjörn B, Konrad, Peter, Nyman, Niklas, Skiöldebrand, Claes, Steuer, Johnny, Takolander, Rabbe, Malmstedt, Jonas, Acosta, Stefan, Björses, Katarina, Brandt, Kerstin, Dias, Nuno, Gottsäter, Anders, Holst, Jan, Kristmundsson, Thorarinn, Kühme, Tobias, Kölbel, Tilo, Lindblad, Bengt, Lindh, Mats, Malina, Martin, Ohrlander, Tomas, Resch, Tim, Rönnle, Viola, Sonesson, Björn, Warvsten, Margareta, Zdanowski, Zbigniew, Campbell, Erik, Kjellin, Per, Lindgren, Hans, Nyberg, Johan, Petersen, Björn, Plate, Gunnar, Pärsson, Håkan, Qvarfordt, Peter, Ignatenko, Pavel, Karpenko, Andrey, Starodubtsev, Vladimir, Chernyavsky, Mikhail A, Golovkova, Maria S, Komakha, Boris B, Zherdev, Nikolay N, Belyasnik, Andrey, Chechulov, Pavel, Kandyba, Dmitry, Stepanishchev, Igor, Csobay-Novák, Csaba, Dósa, Edit, Entz, László, Nemes, Balázs, Szeberin, Zoltán, Barzó, Pál, Bodosi, Mihaly, Fákó, Eniko, Fülöp, Béla, Németh, Tamás, Pazdernyik, Szilárd, Skoba, Krisztina, Vörös, Erika, Chatzinikou, Eleni, Giannoukas, Athanasios, Karathanos, Christos, Koutsias, Stylianos, Kouvelos, Georgios, Matsagkas, Miltiadis, Ralli, Styliani, Rountas, Christos, Rousas, Nikolaos, Spanos, Konstantinos, Brountzos, Elias, Kakisis, John D, Lazaris, Andreas, Moulakakis, Konstantinos G, Stefanis, Leonidas, Tsivgoulis, Georgios, Vasdekis, Spyros, Antonopoulos, Constantine N, Bellenis, Ion, Maras, Dimitrios, Polydorou, Antonios, Polydorou, Victoria, Tavernarakis, Antonios, Ioannou, Nikolaos, Terzoudi, Maria, Lazarides, Miltos, Mantatzis, Michalis, Vadikolias, Kostas, Dzieciuchowicz, Lukasz, Gabriel, Marcin, Krasinski, Zbigniew, Oszkinis, Grzegorz, Pukacki, Fryderyk, Slowinski, Maciej, Stanišic, Michal-Goran, Staniszewski, Ryszard, Tomczak, Jolanta, Zielinski, Maciej, Myrcha, Piotr, Rózanski, Dorota, Drelichowski, Stanislaw, Iwanowski, Wojciech, Koncewicz, Katarzyna, Bialek, Pawel, Biejat, Zbigniew, Czepel, Wojciech, Czlonkowska, Anna, Dowzenko, Anatol, Jedrzejewska, Julia, Kobayashi, Adam, Leszczynski, Jerzy, Malek, Andrzej, Polanski, Jerzy, Proczka, Robert, Skorski, Maciej, Szostek, Mieczyslaw, Andziak, Piotr, Dratwicki, Maciej, Gil, Robert, Nowicki, Miroslaw, Pniewski, Jaroslaw, Rzezak, Jaroslaw, Seweryniak, Piotr, Dabek, Pawel, Juszynski, Michal, Madycki, Grzegorz, Pacewski, Bartosz, Raciborski, Witold, Slowinski, Piotr, Staszkiewicz, Walerian, Bombic, Martin, Chlouba, Vladimír, Fiedler, Jirí, Hes, Karel, Koštál, Petr, Sova, Jindrich, Kríž, Zdenek, Prívara, Mojmír, Reif, Michal, Staffa, Robert, Vlachovský, Robert, Vojtíšek, Bohuslav, Hrbác, Tomáš, Kuliha, Martin, Procházka, Václav, Roubec, Martin, Školoudík, David, Netuka, David, Šteklácová, Anna, Beneš III, Vladimír, Buchvald, Pavel, Endrych, Ladislav, Šercl, Miroslav, Campos Jr, Walter, Casella, Ivan B, de Luccia, Nelson, Estenssoro, André E V, Presti, Calógero, Puech-Leão, Pedro, Neves, Celso R B, da Silva, Erasmo S, Sitrângulo Jr, Cid J, Monteiro, José A T, Tinone, Gisela, Bellini Dalio, Marcelo, Joviliano, Edwaldo E, Pontes Neto, Octávio M, Serra Ribeiro, Mauricio, Cras, Patrick, Hendriks, Jeroen M H, Hoppenbrouwers, Mieke, Lauwers, Patrick, Loos, Caroline, Yperzeele, Laetitia, Geenens, Mia, Hemelsoet, Dimitri, van Herzeele, Isabelle, Vermassen, Frank, Astarci, Parla, Hammer, Frank, Lacroix, Valérie, Peeters, André, Verhelst, Robert, Cirelli, Silvana, Dormal, Pol, Grimonprez, Annelies, Lambrecht, Bart, Lerut, Philipe, Thues, Eddy, De Koster, Guy, Desiron, Quentin, Maertens de Noordhout, Alain, Malmendier, Danielle, Massoz, Mireille, Saad, Georges, Bosiers, Marc, Callaert, Joren, Deloose, Koen, Blanco Cañibano, Estrella, García Fresnillo, Beatriz, Guerra Requena, Mercedes, Morata Barrado, Pilar C, Muela Méndez, Miguel, Yusta Izquierdo, Antonio, Aparici Robles, Fernando, Blanes Orti, Paula, García Dominguez, Luis, Martínez López, Rafael, Miralles Hernández, Manuel, Tembl Ferrairo, José I, Chamorro, Ángel, Macho, Juan, Obach, Víctor, Riambau, Vincent, San Román, Luis, Ahlhelm, Frank J, Blackham, Kristine, Engelter, Stefan, Eugster, Thomas, Gensicke, Henrik, Gürke, Lorenz, Lyrer, Philippe, Mariani, Luigi, Maurer, Marina, Mujagic, Edin, Müller, Mandy, Psychogios, Marios, Stierli, Peter, Stippich, Christoph, Traenka, Christopher, Wolff, Thomas, Wagner, Benjamin, Wiegert, Martina M, Clarke, Sandra, Diepers, Michael, Gröchenig, Ernst, Gruber, Philipp, Isaak, Andrej, Kahles, Timo, Marti, Regula, Nedeltchev, Krassen, Remonda, Luca, Tissira, Nadir, Valença Falcão, Martina, de Borst, Gert J, Lo, Rob H, Moll, Frans L, Toorop, Raechel, van der Worp, Bart H, Vonken, Evert J, Kappelle, Jaap L, Jahrome, Ommid, Vos, Floris, Schuiling, Wouter, van Overhagen, Hendrik, Keunen, Rudolf W M, Knippenberg, Bob, Wever, Jan J, Lardenoije, Jan W, Reijnen, Michel, Smeets, Luuk, van Sterkenburg, Steven, Fraedrich, Gustav, Gizewski, Elke, Gruber, Ingrid, Knoflach, Michael, Kiechl, Stefan, Rantner, Barbara, Abdulamit, Timur, Bergeron, Patrice, Padovani, Raymond, Trastour, Jean-Christophe, Cardon, Jean-Marie, Le Gallou-Wittenberg, Anne, Allaire, Eric, Becquemin, Jean-Pierre, Cochennec-Paliwoda, Frédéric, Desgranges, Pascal, Hosseini, Hassan, Kobeiter, Hicham, Marzelle, Jean, Almekhlafi, Mohammed A, Bal, Simerpreet, Barber, Phillip A, Coutts, Shelagh B, Demchuk, Andrew M, Eesa, Muneer, Gillies, Michelle, Goyal, Mayank, Hill, Michael D, Hudon, Mark E, Jambula, Anitha, Kenney, Carol, Klein, Gary, McClelland, Marie, Mitha, Alim, Menon, Bijoy K, Morrish, William F, Peters, Steven, Ryckborst, Karla J, Samis, Greg, Save, Supriya, Smith, Eric E, Stys, Peter, Subramaniam, Suresh, Sutherland, Garnette R, Watson, Tim, Wong, John H, Zimmel, L, Flis, Vojko, Matela, Jože, Miksic, Kazimir, Milotic, Franko, Mrdja, Božidar, Stirn, Barbara, Tetickovic, Erih, Gasparini, Mladen, Grad, Anton, Kompara, Ingrid, Miloševic, Zoren, Palmiste, Veronika, Toomsoo, Toomas, Aidashova, Balzhan, Kospanov, Nursultan, Lyssenko, Roman, Mussagaliev, Daulet, Beyar, Rafi, Hoffman, Aaron, Karram, Tony, Kerner, Arthur, Nikolsky, Eugenia, Nitecki, Samy, Andonova, Silva, Bachvarov, Chavdar, Petrov, Vesko, Cvjetko, Ivan, Vidjak, Vinko, Halužan, Damir, Petrunic, Mladen, Liu, Bao, Liu, Chang-Wei, Bartko, Daniel, Beno, Peter, Rusnák, František, Zelenák, Kamil, Ezura, Masayuki, Inoue, Takashi, Kimura, Naoto, Kondo, Ryushi, Matsumoto, Yasushi, Shimizu, Hiroaki, Endo, Hidenori, Furui, Eisuke, Bakke, Søren, Krohg-Sørensen, Kristen, Nome, Terje, Skjelland, Mona, Tennøe, Bjørn, Albuquerque e Castro, João, Alves, Gonçalo, Bastos Gonçalves, Frederico, de Aragão Morais, José, Garcia, Ana C, Valentim, Hugo, Vasconcelos, Leonor, Belcastro, Fernando, Cura, Fernando, Zaefferer, Patricio, Abd-Allah, Foad, Eldessoki, Mohamed H, Heshmat Kassem, Hussein, Soliman Gharieb, Haytham, Colgan, Mary P, Haider, Syed N, Harbison, Joe, Madhavan, Prakash, Moore, Dermot, Shanik, Gregor, Kazan, Viviane, Nazzal, Munier, and Ramsey-Williams, Vicki

Published
2021
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39. Endograft Thrombosis as an Indication for Open Conversion after Endovascular Aneurysm Repair in a Multicenter Experience over 25 Years

Author

Fornasari, Anna, Perini, Paolo, Gargiulo, Mauro, Silingardi, Roberto, Michelagnoli, Stefano, Bonardelli, Stefano, Bellosta, Raffaello, Freyrie, Antonio, Mersanne, Arianna, Gerosa, Cecilia, Mariani, Erica, Faggioli, Gianluca, Ancetti, Stefano, Migliari, Mattia, Gennai, Stefano, Chisci, Emiliano, Melloni, Andrea, Attisani, Luca, Piffaretti, Gabriele, Mauri, Francesca, Troisi, Nicola, Berchiolli, Raffaella, Fanelli, Mara, Paciaroni, Elisa, and Marchetti, Federica

Abstract

To describe the outcomes of aortic endograft thrombosis (AET) as an indication for open conversion (OC) after endovascular aortic aneurysm repair (EVAR) in a multicenter experience.

Published
2024
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44. List of Contributors

Author

Abi-Aad, Karl, primary, Abu-Halimah, Shadi, additional, AbuRahma, Ali F., additional, Acharya, Yogesh, additional, Anain, Paul, additional, Aridi, Hanaa Dakour, additional, Asciutto, Giuseppe, additional, Atwal, Gursant S., additional, Avgerinos, Efthymios D., additional, Ayad, Micheal T., additional, Beecher, Jeffrey S., additional, Bendok, Bernard R., additional, Brinster, Clayton J., additional, Cantos, Andrew J., additional, Carpenter, Jeffrey P., additional, Chaer, Rabih A., additional, Chang, Jason, additional, Cherr, Gregory S., additional, Cheun, Tracy J., additional, Chuter, Timothy A.M., additional, Curl, Richard, additional, Dake, Michael D., additional, Darling, R. Clement, additional, Davies, Mark G., additional, Doshi, Dolly Thakkar, additional, Dosluoglu, Hasan H., additional, D’Souza, Ashwini, additional, Dryjski, Maciej L., additional, Edwards, Jeffrey B., additional, Eijkenboom, Quirine L., additional, Faggioli, Gianluca, additional, Farber, Mark A., additional, Farnsworth, Joseph B., additional, Fennell, Vernard S., additional, Feyko, Jared T., additional, Flohr, Tanya R., additional, Fontenot, Danielle, additional, Gallitto, Enrico, additional, Gargiulo, Mauro, additional, Gillespie, David L., additional, Go, Catherine C., additional, Hall, Michael R., additional, Harris, Linda M., additional, Hnath, Jeffrey C., additional, Hynes, Niamh, additional, Illig, Karl A., additional, Jayakumar, Lalithapriya, additional, Kapadia, Samir R., additional, Kärkkäinen, Jussi M., additional, Kasprzak, Piotr M., additional, Kavanagh, Edel P., additional, Khan, Sikandar Z., additional, Kostun, Zachary W., additional, Koudoumas, Dimitrios, additional, Krishna, Chandan, additional, Krishnaswamy, Amar, additional, Lal, Brajesh K., additional, Lehrman, Evan D., additional, Levy, Elad I., additional, Liang, Patric, additional, Lim, Jaims, additional, Malas, Mahmoud B., additional, Marone, Luke, additional, McKinsey, James F., additional, McMackin, Katherine K., additional, Mehta, Manish, additional, Meier, George H., additional, Milner, Ross, additional, Montross, Brittany C., additional, Morrison, John F., additional, Mouawad, Nicolas J., additional, Mousa, Albeir Y., additional, Oderich, Gustavo S., additional, O’Donnell, Thomas F.X., additional, Oikonomou, Kyriakos, additional, Ou, Christine, additional, Panneton, Jean M., additional, Patra, Devi P., additional, Pfister, Karin, additional, Pini, Rodolfo, additional, Powell, Richard J., additional, Raffetto, Joseph D., additional, Ramdon, Andre R., additional, Rathore, Animesh, additional, Ravin, Reid, additional, Reed, Amy B., additional, Reilly, Brendon, additional, Resch, Timothy, additional, Rhee, Robert, additional, Rivero, Mariel, additional, Sattur, Mithun G., additional, Schermerhorn, Marc L., additional, Shakir, Hakeem J., additional, Shames, Murray L., additional, Shih, Michael, additional, Shivapour, Daniel M., additional, Siddiqui, Adnan H., additional, Snyder, Kenneth V., additional, Stella, Andrea, additional, Stoner, Michael C., additional, Sultan, Sherif, additional, Sywak, Michael, additional, Tallarita, Tiziano, additional, Tan, Tze-Woei, additional, Tenorio, Emanuel R., additional, TerBush, Matthew J., additional, Tian, Fucheng, additional, Tran, Kenneth, additional, Ullery, Brant W., additional, Vakharia, Kunal, additional, Waldman, David L., additional, Wang, Sophie, additional, Weintraub, Joshua L., additional, Welz, Matthew E., additional, Woo, Karen, additional, Wooster, Mathew, additional, Wu, Winona, additional, Yacoub, Michael, additional, Zacharias, Nikolaos, additional, and Zhang, Wayne W., additional

Published
2022
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45. Silent brain ischemia within the TAXINOMISIS framework: association with clinical and advanced ultrasound metrics.

Author

Kigka, Vassiliki, Carrozzi, Alessandro, Gramegna, Laura Ludovica, Siogkas, Panagiotis K., Potsika, Vassiliki, Tsakanikas, Vassilis, Kallmayer, Michael, Obach, Victor, Riambau, Vincente, Spinella, Giovanni, Pratesi, Giovanni, Cirillo, Luigi, Manners, David Neil, Pini, Rodolfo, Faggioli, Gianluca, de Borst, Gert J., Galyfos, George, Sigala, Frangiska, Mutavdzic, Perica, and Jovanovic, Marija

Subjects
CAROTID artery ultrasonography, CAROTID artery stenosis, ASYMPTOMATIC patients, MAGNETIC resonance imaging, COMPUTATIONAL fluid dynamics
Abstract

Introduction: The relationship between carotid artery stenosis (CAS) and ipsilateral silent brain ischemia (SBI) remains unclear, with uncertain therapeutic implications. The present study, part of the TAXINOMISIS project (nr. 755,320), aimed to investigate SBIs in patients with asymptomatic CAS, correlating them with clinical, carotid ultrasonographic data, and CFD analyses. Methods: The TAXINOMISIS clinical trial study (nr. NCT03495830) involved six vascular surgery centers across Europe, enrolling patients with asymptomatic and symptomatic CAS ranging from 50 to 99%. Patients underwent carotid ultrasound and magnetic resonance imaging (MRI), including brain diffusionweighted, T2-weighted/FLAIR, and T1-weighted sequences. Brain MRI scans were analyzed for the presence of SBI according to established definitions. Ultrasound assessments included Doppler and CFD analysis. Only asymptomatic patients were included in this substudy. Results: Among 195 asymptomatic patients, the mean stenosis (NASCET) was 64.1%. Of these, a total of 33 patients (16.9%) had at least one SBI detected on a brain MRI scan. Specifically, 19 out of 33 patients (57.6%) had cortical infarcts, 4 out of 33 patients (12.1%) had ipsilateral lacunar infarcts, 6 out of 33 patients had (18.2%) subcortical infarcts, 1 out of 33 patients (3.0%) had both cortical and lacunar infarcts, and 3 out of 33 patients (9.1%) both cortical and subcortical infarcts. Patients with SBIs exhibited significantly higher risk factors, including a higher body mass index (28.52  ±  9.38 vs. 26.39  ±  3.35, p  =  0.02), diastolic blood pressure (80.87  ±  15.73  mmHg vs. 80.06  ±  8.49  mmHg, p  =  0.02), creatinine levels (93.66  ±  34.61  μmol/L vs. 84.69  ±  23.67  μmol/L, p  =  0.02), and blood triglycerides (1.8  ±  1.06  mmol/L vs. 1.48  ±  0.78  mmol/L, p  =  0.03). They also had a higher prevalence of cardiovascular interventions (29.6% vs. 13.8%, p  =  0.04), greater usage of third/fourth-line antihypertensive treatment (50%vs16%, p  =  0.03), and anticoagulant medications (60% vs. 16%, p  =  0.01). Additionally, the number of contralateral cerebral infarcts was higher in patients with SBIs (35.5% vs. 13.4%, p  <  0.01). Moreover, carotid ultrasound revealed higher Saint Mary’s ratios (15.33  ±  12.45 vs. 12.96  ±  7.99, p  =  0.02), and CFD analysis demonstrated larger areas of low wall shear stress (WSS) (0.0004  ±  0.0004  m2 vs. 0.0002  ±  0.0002  m2, p  <  0.01). Conclusion: The TAXINOMISIS clinical trial provides valuable insights into the prevalence and risk factors associated with SBIs in patients with moderate asymptomatic carotid stenosis. The findings suggest that specific hemodynamic and arterial wall characteristics may contribute to the development of silent brain infarcts. [ABSTRACT FROM AUTHOR]

Published
2024
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46. CO 2 Angiography in the Standard and Complex Endovascular Repair of the Abdominal Aorta—A Narrative Review of the Literature.

Author

Spath, Paolo, Caputo, Stefania, Campana, Federica, Gallitto, Enrico, Pini, Rodolfo, Mascoli, Chiara, Vacirca, Andrea, Faggioli, Gianluca, and Gargiulo, Mauro

Subjects
ENDOVASCULAR aneurysm repair, ENDOVASCULAR surgery, LITERATURE reviews, CONTRAST media, KIDNEY physiology, DIGITAL subtraction angiography
Abstract

Background/Objectives: Carbon dioxide digital-subtraction angiography (CO2-DSA) is an increasingly adopted technique in endovascular aortic repair (EVAR) and fenestrated/branched EVAR (F/B-EVAR); it is used to reduce the amount of iodinate contrast medium (ICM) and prevent postoperative renal function worsening (PO-RFW). Our aim is to report results from the literature on EVAR and F/B-EVAR procedures using CO2-DSA, together with wider applications in aortic endovascular treatment. Methods: We performed a literature review by searching electronic databases for published data on CO2-DSA during EVAR and F/B-EVAR procedures. The endpoints were postoperative renal function worsening (PO-RFW) and efficacy of intraoperative arterial visualization. Further, applications of CO2 for thoracic endovascular aortic repair (TEVAR) were described. Results: Seventeen studies reporting results on CO2-DSA in EVAR (644 patients) were retrieved. Overall, 372 (58%) procedures were performed with CO2 alone, and 272 (42%) were performed with CO2+ICM. Eight studies analyzed the effect of CO2-DSA angiography on PO-RFW; four studies showed a significantly lower rate of PO-RFW compared to ICM. Five studies (153 patients) analyzed intraoperative arterial visualization with CO2-DSA; renal and hypogastric arteries were effectively visualized in 69% and 99% of cases, respectively. The use of CO2-DSA in F/B-EVAR has not been widely investigated. The largest series reported that PO-RFW was lower in the CO2 vs. ICM group. Conclusions: Carbon dioxide is widely applied in modern aortic endovascular treatment. CO2-DSA for EVAR and F/B-EVAR is an efficient technique for reducing PO-RFW while allowing acceptable arterial intraoperative visualization. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Sex Influence on Fenestrated and Branched Endovascular Aortic Aneurysm Repair: Outcomes From a National Multicenter Registry.

Author

Isernia, Giacomo, Simonte, Gioele, Gallitto, Enrico, Bertoglio, Luca, Fargion, Aaron, Melissano, Germano, Chiesa, Roberto, Lenti, Massimo, Pratesi, Carlo, Faggioli, Gianluca, Gargiulo, Mauro, Luigi, Baccani, Luca, Bertoglio, Roberto, Chiesa, Gianluca, Faggioli, Aaron, Fargion, Cecilia, Fenelli, Gianluigi, Fino, Enrico, Gallitto, and Mauro, Gargiulo

Abstract

Introduction: Women are generally underrepresented in trials focusing on aortic aneurysm. Nevertheless, sex-related differences have recently emerged from several studies and registries. The aim of this research was to assess whether sex-related anatomical disparities existed in fenestrated and branched aortic repair candidates and whether these discrepancies could influence endovascular repair outcomes. Methods: Data from all consecutive patients treated during the 2008–2019 period within the Italian Multicenter fenestrated or branched endovascular aortic repair (F/BEVAR) Registry were included in the present study. Propensity matching was performed using a logistic regression model adjusted for demographic data and comorbidities to obtain comparable male and female samples. The selection model led to a final study population of 176 patients (88 women and 88 men) among the total initial cohort of 596. Study endpoints were technical and clinical success, overall survival, aneurysm-related death, and reintervention rates evaluated at 30 days and during follow-up. Results: Twenty-eight patients (15.9%) received urgent/emergent repair. In most of the cases (71.6%), women received treatment for extensive thoracoabdominal pathology (Crawford type I, II, or III aneurysm rather than type IV or juxta-pararenal) versus 46.6% of men (p=0.001). Female patients presented with more challenging iliac accesses with at least one side considered hostile in 27.3% of the cases (vs 13.6% in male patients, p=0.039). Finally, women had significantly smaller visceral vessels. Women had significantly worse operative outcomes, with an 86.2% technical success rate versus 96.6% in the male population (p=0.016). No differences were recorded in terms of 30-day reinterventions between men and women. The 5-year estimate of freedom from late reintervention, according to Kaplan-Meier analysis, was 85.6% in men versus 81.6% in women (p=ns). No aneurysm-related death was recorded during follow-up (median observational time, 23 months [interquartile range, 7–45 months]). Conclusion: Women presented a significantly higher incidence of thoracoabdominal aneurysms, smaller visceral vessels, and more complex iliofemoral accesses, resulting in a significantly lower technical success after F/BEVAR. Further studies assessing sex-related differences are needed to properly determine the impact on outcomes and stratify procedural risks. Clinical Impact: Women are generally underrepresented in trials focusing on aortic aneurysms. Aiming to assess whether sex may affect outcomes after a complex endovascular aortic repair, a propensity score selection was applied to a total population of 596 patients receiving F/BEVAR aortic repair with the Cook platform, matching each treated female patient with a corresponding male patient. Women presented more frequently a thoracoabdominal aneurysm extent, smaller visceral vessels, and complex iliofemoral accesses, resulting in significantly worse operative outcomes, with an 86.2% technical success versus 96.6% (p=0.016). No differences were recorded in terms of short-term and mid-term reinterventions. According to these results, careful and critical assessment should be posed in case of female patients receiving complex aortic repair, especially regarding preoperative anatomical evaluation and clinical selection with appropriate surgical risk stratification. [ABSTRACT FROM AUTHOR]

Published
2024
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