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In the nearby universe jets from AGN are observed to have a dramatic impact on their surrounding extragalactic environment. Their effect at the `cosmic noon' (z>1.5), the epoch when star formation and AGN activity peak, is instead much less constrained. Here we present a study of the giant (750 kpc) radio galaxy 103025+052430 located at the centre of a protocluster at redshift z=1.7, with a focus on its interaction with the external medium. We present new LOFAR observations at 144 MHz, which we combine with VLA 1.4 GHz and 0.5-7 keV Chandra archival data. The new map at 144 MHz confirms that the source has a complex morphology, possibly consistent with the `hybrid morphology' classification. The large size of the source gave us the possibility to perform a resolved radio spectral index analysis, a very unique opportunity for a source at such high redshift. This reveals a tentative flattening of the radio spectral index at the edge of the backflow in the Western lobe, which might be indicating plasma compression. The spatial coincidence between this region and the thermal X-ray bubble C suggests a causal connection between the two. Contrary to previous estimates for the bright X-ray component A, we find that inverse Compton scattering between the radio-emitting plasma of the Eastern lobe and the CMB photons can account for a large fraction (~45%-80%) of its total 0.5-7 keV measured flux. Finally, the X-ray bubble C, which is consistent with a thermal origin, is found to be significantly overpressurised with respect to the ambient medium. This suggests that it will tend to expand and release its energy in the surroundings, contributing to the overall intracluster medium heating. Overall, 103025+052430 gives us the chance to investigate the interaction between AGN jets and the surrounding gas in a system that is likely the predecessor of the rich galaxy clusters we all well know at z=0., 12 pages, 5 figures, 2 tables, accepted for publication in A&A

Source finding is one of the most challenging tasks in upcoming radio continuum surveys with SKA precursors, such as the Evolutionary Map of the Universe (EMU) survey of the Australian SKA Pathfinder (ASKAP) telescope. The resolution, sensitivity, and sky coverage of such surveys is unprecedented, requiring new features and improvements to be made in existing source finders. Among them, reducing the false detection rate, particularly in the Galactic plane, and the ability to associate multiple disjoint islands into physical objects. To bridge this gap, we developed a new source finder, based on the Mask R-CNN object detection framework, capable of both detecting and classifying compact, extended, spurious, and poorly imaged sources in radio continuum images. The model was trained using ASKAP EMU data, observed during the Early Science and pilot survey phase, and previous radio survey data, taken with the VLA and ATCA telescopes. On the test sample, the final model achieves an overall detection completeness above 85\%, a reliability of $\sim$65\%, and a classification precision/recall above 90\%. Results obtained for all source classes are reported and discussed., 18 pages, 11 figures

Context. Exoplanetary properties strongly depend on stellar properties: to know the planet with accuracy and precision it is necessary to know the star as accurately and precisely as possible. Aims. Our immediate aim is to characterize in a homogeneous and accurate way a sample of 27 transiting planet-hosting stars observed within the Global Architecture of Planetary System program. For the wide visual binary XO-2, we considered both components (N: hosting a transiting planet; S: without a known transiting planet). Our final goal is to widely analyze the sample by deriving several stellar properties, abundances of many elements, kinematic parameters, and discuss them in the context of planetary formation. Methods. We determined the stellar parameters (effective temperature, surface gravity, rotational velocity) and abundances of 26 elements (Li, C, N, O, Na, Mg, Al, Si, S, Ca, Sc, Ti, V, Cr, Fe, Mn, Co, Ni, Cu, Zn, Y, Zr, Ba, La, Nd, Eu). Our study is based on high-resolution HARPS-N at TNG and FEROS at ESO spectra and uniform techniques. Depending on stellar parameters and chemical elements, we used line equivalent widths or spectral synthesis methods. We derived kinematic properties taking advantage of Gaia data and for the first time in exoplanet host stars we estimated ages using elemental ratios as chemical clocks. Results. The effective temperature of our stars is ~4400–6700 K, while the iron abundance [Fe/H] is within −0.3 and 0.4 dex. Lithium is present in seven stars. The [X/H] and [X/Fe] abundances versus [Fe/H] are consistent with the Galactic chemical evolution. The dependence of [X/Fe] with the condensation temperature is critically analyzed with respect to stellar and kinematic properties. All targets with measured C and O abundances show C/O < 0.8, compatible with Si present in rock-forming minerals. Mean C/O and [C/O] values are slightly lower than for the Sun. Most of targets show 1.0 < Mg/Si < 1.5, compatible with Mg distributed between olivine and pyroxene, and mean Mg/Si lower than for the Sun. HAT-P-26, the target hosting the lowest-mass planet, shows the highest Mg/Si ratio. From our chemodynamical analysis we find agreement between ages and position within the Galactic disk. Finally, we note a tendency for higher-density planets to be around metal-rich stars and hints of higher stellar abundances of some volatiles (e.g., O) for lower-mass planets. We cannot exclude that part of our results could be also related to the location of the stars within the Galactic disk. Conclusions. We try to trace the planetary migration scenario from the composition of the planets related to the chemical composition of the hosting stars. This kind of study will be useful for upcoming space mission data to get more insights into the formation-migration mechanisms.

With the aim of facilitating the ex vivo manipulation of peripheral blood hematopoietic progenitors (CPCs = circulating progenitor cells) collected by leukapheresis, we removed polymorphonuclear cells and monocytes that naturally adhere to nylon wool fibers. Leukapheresed cells harvested at the time of hematopoietic recovery after cancer therapy with high-dose cyclophosphamide plus hematopoietic growth factors were incubated with nylon wool fibers for 1 h at 37 degrees C. Evaluation of the cells non-adherent to the nylon wool in all experiments (n = 14) showed that the median recovery of nucleated cells and CPCs detected as CD34+ cells, CFU-GM and BFU-E was 16.4% (range 4.8%-34.0%), 60.0% (range 30.8-80.8%), 60.9% (range 33.4-74.5%) and 65.5% (range 30.8-69.2%), respectively. Therefore exposure to the nylon wool determined a selective removal of mature cells and a complementary enrichment of CPCs. The wide range of results depended on the significantly different cell compositions of the unmanipulated leukaphereses. The latter from patients receiving rhG-CSF (n = 10) comprised a median of 88.5% (range 77.8-93.8%) and 11.5% (range 6.2-22.2%) polymorphonuclear and mononuclear cells, respectively. In contrast, leukaphereses from patients receiving rhGM-CSF or PIXY321 (n = 4) comprised a median of 71.1% (range 55.4-85.0%) and 28.9% (range 15.0-44.6%) polymorphonuclear and mononuclear cells, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

INSULIN, epinephrine and desoxycorticosterone acetate have each been reported as affecting the level of blood potassium. In spite of the generally conceded fact that desoxycorticosterone is not a natural hormone of the adrenal cortex much emphasis has been placed on the role of this steroid in attempts to explain potassium homeostasis in the organism (Sayers, 1950). This status of desoxycorticosterone is the result of evidence in the literature that the level of blood potassium is increased after adrenalectomy and that plasma potassium is significantly lowered following administration of desoxycorticosterone probably by inhibiting potassium reabsorption in the kidney tubules (Harrison and Darrow, 1939; Swingle and Remington, 1944; Rommelt, Sartorius and Pitts, 1949). Evidence that epinephrine and insulin induced a rapid and significant fall in plasma potassium level in man and animals has been reported by several investigators (Houssay et al., 1937; D'Silva, 1937; Flocks et al., 1939; Keys, 1938a, 1938b; ...