Search

Pests significantly impact agricultural productivity, making early detection crucial for maximizing yields. This paper explores the use of machine learning models to predict olive fly and red spider mite infestations in Andalusia. Four datasets on crop phenology, pest populations, and damage levels were used, with models developed using the Python package H2O, which focuses on interpretability through SHAP values and ICE plots. The results showed high precision in predicting pest outbreaks, particularly for the olive fly, with minimal differences between models using feature selection. In the vineyard dataset, the selection of characteristics improved the performance of the model by reducing the MAE and increasing R2. Explainability techniques identified solar radiation and wind direction as key factors in olive fly predictions, while past pest occurrences and wind velocity were influential for red spider mites, providing farmers with actionable insights for timely pest control.

Agriculture plays a key role in the development of today's society. The population is constantly increasing, and increased production is required that is contained and consumes resources sustainably. Automation and robotization are one way to achieve this goal. Intensive agriculture, and in particular greenhouse agriculture, modifies the production environment to improve productivity while optimising the use of resources. This article studies the current feasibility of using robots in greenhouses from five perspectives: technical, economic, social, legal, and environmental. To this end, two representative applications have been selected, spraying and harvesting, in a type of greenhouse that is also representative, the Mediterranean type, which accounts for 92 % of the total greenhouse area worldwide. The work can help companies and researchers make technical and economic decisions about the introduction of robotics in greenhouses. It concludes that there are currently gaps in the technical and legal aspects, and that the business model is not profitable at present, however, robotics in agriculture will be fully viable in the future, given the growing trend towards service robots, supported by a strong interest in developing a particular legislative regulation, and a technology that evolves very quickly, reducing its costs and ensuring the sustainability of the processes.

Ultrafast electron diffraction (UED) instruments typically operate at kHz or lower repetition rates and rely on indirect detection of electrons. However, these experiments encounter limitations because they are required to use electron beams containing a relatively large number of electrons (≫100 electrons/pulse), leading to severe space-charge effects. Consequently, electron pulses with long durations and large transverse diameters are used to interrogate the sample. Here, we introduce a novel UED instrument operating at a high repetition rate and employing direct electron detection. We operate significantly below the severe space-charge regime by using electron beams containing 1–140 electrons per pulse at 30 kHz. We demonstrate the ability to detect time-resolved signals from thin film solid samples with a difference contrast signal, Δ I / I 0 , and an instrument response function as low as 10−5 and 184-fs (FWHM), respectively, without temporal compression. Overall, our findings underscore the importance of increasing the repetition rate of UED experiments and adopting a direct electron detection scheme, which will be particularly impactful for gas-phase UED. Our newly developed scheme enables more efficient and sensitive investigations of ultrafast dynamics in photoexcited samples using ultrashort electron beams.

Background: Guillain–Barré syndrome (GBS) is an acute inflammatory polyneuropathy that can lead to respiratory failure. In this study, we evaluate early clinical risk factors for respiratory failure at the time of hospital admission. Methods: We studied a retrospective cohort of patients with GBS admitted to a tertiary care center. The potential risk factors studied were sociodemographic characteristics, GBS symptoms, overall and cervical muscle weakness (Medical Research Council [MRC] scores), electromyography findings, and cerebrospinal fluid analysis findings. Unadjusted odds ratios (OR) were calculated and exact logistic regression analysis (adjusted OR) performed to assess the association between baseline risk factors and respiratory failure. Results: Overall, 13 of 113 (12%) patients included in the study developed respiratory failure. Unadjusted analyses showed that involvement of any cranial nerve (OR: 14.7; 95% CI, 1.8–117.1), facial palsy (OR: 17.3; 95% CI, 2.2–138.0), and bulbar weakness (OR: 10.7; 95% CI, 2.3–50.0) were associated with increased risk of respiratory failure. Lower MRC sum scores (for scores 3) were independently associated with respiratory failure. Conclusions: Bulbar and neck muscle weakness at admission are clinical predictors of increased risk of respiratory failure in patients with GBS. These findings could guide the adequate management of high-risk patients. Resumen: Introducción: El síndrome de Guillain-Barré es una polineuropatía inflamatoria aguda que puede causar insuficiencia respiratoria. Evaluamos los factores de riesgo clínicos en el momento de la hospitalización. Métodos: Realizamos un estudio de una cohorte retrospectiva de pacientes con síndrome de Guillain-Barré hospitalizados en un centro de tercer nivel. Analizamos las características sociodemográficas, síntomas de la enfermedad, fuerza muscular general y cervical (escala del Medical Research Council [MRC]), hallazgos electromiográficos, y resultados del análisis del líquido cefalorraquídeo. Calculamos el odds ratio (OR) sin ajustar y realizamos una regresión logística exacta (OR ajustada) para evaluar la asociación entre los factores de riesgo y la insuficiencia respiratoria. Resultados: Trece de los 113 pacientes incluidos (12%) presentó insuficiencia respiratoria. Los análisis no ajustados mostraron una asociación entre mayor riesgo de insuficiencia respiratoria y la afectación de cualquier par craneal (OR: 14,7; IC 95%, 1,8-117,1), parálisis facial (OR: 17,3; IC 95%, 2,2-138,0) y debilidad bulbar (OR: 10,7; IC 95%, 2,3-50,0). Unas puntuaciones más bajas en la MRC-total (puntuaciones 3) se asociaron de forma independiente con la insuficiencia respiratoria. Conclusiones: La presencia de debilidad bulbar y cervical en el momento de la hospitalización es un factor de riesgo de insuficiencia respiratoria en pacientes con síndrome de Guillain-Barré. Estos hallazgos pueden servir de guía para el manejo de los pacientes con mayor riesgo de presentar dicha complicación.

We investigate the most severe rainfall event ever experienced in Ho Chi Minh City (HCMC), Vietnam. It occurred on 25 November 2018 when Typhoon (TY) Usagi directly hit HCMC. During this event, there was more than 300 mm of rainfall over 24 h which led to flooding and considerable material damage. We propose an in-depth study of TY-induced, compound flood drivers at a short timescale by focusing on the days before and after the event. We use a set of data analysis and signal processing tools to characterize and quantify both coastal and inland effects on the hydrosystem. We found that TY Usagi made landfall without forming a significant storm surge. The extreme rainfall does not translate into immediate river discharge but presents a 16 h time lag between peak precipitation and peak residual discharge. Nevertheless, increased river water levels can be seen at both urban and upstream stations with a similar time lag. At the upstream river station, residual discharge represents 1.5 % of available rainwater, and evidence of upstream widespread flooding was found. At the urban river station, we assess the potential surface runoff during the event to be 8.9 % of the upstream residual discharge. However, a time lag in peak river water level and peak rainfall was found and attributed to the combination of high tide and impervious streets which prevented the evacuation of rainwater and resulted in street flooding of up to 0.8 m. Overall, it was found that despite not having a significant storm surge, the coastal tidal forcing is the predominant compound flood driver even during severe, heavy rainfall with tidal fluctuations in river water level and respective discharge much larger than the residuals.

Resumen: La compresión neurológica se presenta entre el 10-20% de los pacientes que desarrollan una metástasis vertebral. En la última década, la evolución de las técnicas diagnósticas y médicas oncológicas, el cambio de la radiación convencional externa a la radiocirugía y los nuevos instrumentales quirúrgicos, han hecho que el tratamiento de estos pacientes deba de ser indicado de forma personalizada y en consenso, de forma multidisciplinar, en comisiones específicas.Hoy, el estado biológico del paciente, la presencia de inestabilidad mecánica, la valoración neurológica y el grado de compresión epidural, así como la mejor categorización pronóstica del tumor, se establecen como los factores de decisión previa a la indicación del tratamiento quirúrgico, tratamiento que ha pasado de un concepto «citorreductor» al de «separador» o «preparador» de la médula para asegurar una radiocirugía segura. Abstract: Neurological compression occurs in 10%-20% of patients who develop spinal metastases. In the last decade, the evolution of oncological diagnostic and medical techniques, the change from conventional external radiation to radiosurgery and the new surgical instruments have meant that the treatment of these patients must be indicated in a personalized manner and by consensus, multidisciplinary way, in specific commissions.Today, the biological state of the patient, the presence of mechanical instability, the neurological assessment and degree of epidural compression, as well as the best prognostic categorization of the tumor, are established as decision factors prior to the indication of surgical treatment, treatment that has passed from a cytoreductive concept to that of a spinal cord release from tumor in order to ensure safe radiosurgery.

Resumen: Introducción: El infarto medular es una entidad infrecuente y con elevada morbilidad. El diagnóstico puede resultar difícil y el tratamiento óptimo sigue siendo controvertido. Existen pocas series de casos publicadas. Métodos: Estudio retrospectivo de infarto medular en un hospital terciario desde 1999 a 2020. Se evaluaron la etiología, las características clínicas, radiológicas, terapéuticas y pronósticas. Resultados: Se incluyeron 41 pacientes (58,5% varones, edad media 61 ±17 años). Treinta y un pacientes (75,6%) presentaban factores de riesgo vascular (FRV). Presentaron déficit motor (39, 95,1%), dolor (20, 48,8%), déficit sensitivo (33, 80,4%) y alteración autonómica (24, 58,5%). Se realizó resonancia magnética (RM) en 37 pacientes (90,2%). En los 12 pacientes con secuencias de difusión, esta estaba alterada en 10. La localización más afectada fue la dorsal (68,2%). Se realizó estudio vascular en 33 pacientes (80,4%). Las etiologías más frecuentes fueron disección aórtica en 6, ateroesclerosis demostrada en estudio vascular en 6, embolia fibrocartilaginosa en 6, posquirúrgico en 5 e hipotensión en 4. El mecanismo etiológico quedó sin filiar en 12 pacientes (29,3%), 9 presentaban FRV. Al final del periodo de seguimiento (mediana 24 meses, rango intercuartílico 3-70), 12 pacientes (29,2%) presentaban deambulación autónoma. La presencia de FRV y la paraparesia se asociaron significativamente a peor pronóstico (p

Introduction: Spinal cord infarction is a rare disease with a high rate of morbidity. Its diagnosis can be challenging and controversy remains regarding the best treatment. Few case series have been published. Methods: We conducted a retrospective review of cases of spinal cord infarction attended in a tertiary hospital from 1999 to 2020. Aetiology and clinical, imaging, and prognostic features were assessed. Results: Forty-one patients (58.5% men, mean [standard deviation] age 61 [17] years) were included in the study. Thirty-one patients (75.6%) presented vascular risk factors. Motor deficits were recorded in 39 (95.1%), pain in 20 (48.8%), sensory deficits in 33 (80.4%), and autonomic dysfunction in 24 (58.5%). MRI was performed in 37 (90.2%) patients. Diffusion-weighted images were available for 12 patients, with 10 showing diffusion restriction. The thoracic region was the most frequently affected (68.2%). Vascular imaging studies were performed in 33 patients (80.4%). The most frequent aetiologies were aortic dissection (6 cases), atherosclerosis demonstrated by vascular imaging (6 cases), fibrocartilaginous embolism (6 cases), surgery (5 cases), and hypotension (4 cases). Aetiology was undetermined in 12 patients (29.3%), although 9 of these presented vascular risk factors. At the end of the follow-up period (median, 24 months; interquartile range, 3–70), 12 patients (29.2%) were able to walk without assistance. Vascular risk factors and paraparesis were significantly associated with poorer prognosis (P

Abstract Fibroblasts have a considerable functional and molecular heterogeneity and can play various roles in the tumor microenvironment. Here we identify a pro-tumorigenic IL1R1+, IL-1-high-signaling subtype of fibroblasts, using multiple colorectal cancer (CRC) patient single cell sequencing datasets. This subtype of fibroblasts is linked to T cell and macrophage suppression and leads to increased cancer cell growth in 3D co-culture assays. Furthermore, both a fibroblast-specific IL1R1 knockout and IL-1 receptor antagonist Anakinra administration reduce tumor growth in vivo. This is accompanied by reduced intratumoral Th17 cell infiltration. Accordingly, CRC patients who present with IL1R1-expressing cancer-associated-fibroblasts (CAFs), also display elevated levels of immune exhaustion markers, as well as an increased Th17 score and an overall worse survival. Altogether, this study underlines the therapeutic value of targeting IL1R1-expressing CAFs in the context of CRC.

Resumen: Introducción y objetivos: La cirugía bariátrica es el tratamiento más efectivo para la pérdida de peso, con control de comorbilidades. Con bajas tasas de complicaciones, las razones para una reintervención pueden ser complicaciones mayores o falla/reganancia de peso. También se presentan problemas no quirúrgicos como anemia, deshidratación, dolor crónico y desnutrición, entre otros. El objetivo fue analizar las principales causas de cirugía revisional, reoperación y readmisión en un centro bariátrico de referencia. Métodos: Estudio retrospectivo de pacientes sometidos a cirugía bariátrica entre 2012 y 2019. Se realizó un análisis basal incluyendo datos demográficos, antropométricos y perioperatorios y un subanálisis con las principales indicaciones de readmisión y complicaciones. Resultados: Se realizaron 776 cirugías primarias (649 BPGYR, 127 MG y 10 cirugías de revisión), incluyendo 99 pacientes para el estudio: 10 de cirugía revisional, 44 reoperaciones y 45 readmisiones. La incidencia de cirugía revisional fue 1,2%, reoperación y readmisión 5,6% y 5,8% respectivamente. El 50% de las cirugías revisionales fue por pérdida insuficiente o reganancia de peso. Las causas más frecuentes de reoperación fueron: colecistitis (38.6%) y hernias internas (9.1%); las causas de readmisión más comunes fueron dolor abdominal inespecífico (35.5%) y deshidratación (24.4%). Conclusión: Las causas más frecuentes de readmisión poscirugía fueron enfermedades no quirúrgicas, seguido de reoperaciones no bariátricas y, finalmente, cirugías de revisión. Las reoperaciones tempranas por complicaciones tienen una incidencia baja. Es importante conocer lo previo para identificar a los pacientes con mayor riesgo y así prevenir complicaciones mayores. Abstract: Introduction and objectives: Bariatric surgery is the most effective treatment for weight loss, with comorbidity control. With low complication rates, the reasons for reoperation are major complications or weight loss failure/weight regain. Nonsurgical problems can also present, such as anemia, dehydration, chronic pain, and malnutrition, among others. Our aim was to analyze the main causes of revisional surgery, reoperation, and hospital readmission, at a specialized bariatric center. Methods: A retrospective study was conducted on patients that underwent bariatric surgery within the time frame of 2012 and 2019. The baseline analysis included demographic, anthropometric, and perioperative data, as well as a sub-analysis of the main readmission causes and complications. Results: A total of 776 primary surgeries were performed (649 RYGBP, 127 SG, and 10 revisional surgeries), and 99 patients were identified for the study: 10 revisional surgeries, 44 reoperations, and 45 readmissions. The incidence of revisional surgery was 1.2%, reoperation was 5.6%, and readmission 5.8%. Fifty percent of the revisional surgeries were performed due to insufficient weight loss or weight regain; the most frequent causes of reoperation were cholecystitis (38.6%) and internal hernias (9.1%); and the most common causes of readmission were nonspecific abdominal pain (35.5%) and dehydration (24.4%). Conclusion: The most frequent causes of postoperative readmission were nonsurgical events, followed by non-bariatric reoperations, and finally revisional surgeries. There was a low incidence of early reoperations. Knowledge of the abovementioned data is important for identifying higher-risk patients, to prevent major complications.

Introduction and objectives: Bariatric surgery is the most effective treatment for weight loss, with comorbidity control. With low complication rates, the reasons for reoperation are major complications or weight loss failure/weight regain. Nonsurgical problems can also present, such as anemia, dehydration, chronic pain, and malnutrition, among others. Our aim was to analyze the main causes of revisional surgery, reoperation, and hospital readmission, at a specialized bariatric center. Methods: A retrospective study was conducted on patients that underwent bariatric surgery within the time frame of 2012 and 2019. The baseline analysis included demographic, anthropometric, and perioperative data, as well as a sub-analysis of the main readmission causes and complications. Results: A total of 776 primary surgeries were performed (649 RYGBP, 127 SG, and 10 revisional surgeries), and 99 patients were identified for the study: 10 revisional surgeries, 44 reoperations, and 45 readmissions. The incidence of revisional surgery was 1.2%, reoperation was 5.6%, and readmission 5.8%. Fifty percent of the revisional surgeries were performed due to insufficient weight loss or weight regain; the most frequent causes of reoperation were cholecystitis (38.6%) and internal hernias (9.1%); and the most common causes of readmission were nonspecific abdominal pain (35.5%) and dehydration (24.4%). Conclusion: The most frequent causes of postoperative readmission were nonsurgical events, followed by non-bariatric reoperations, and finally revisional surgeries. There was a low incidence of early reoperations. Knowledge of the abovementioned data is important for identifying higher-risk patients, to prevent major complications. Resumen: Introducción y objetivos: La cirugía bariátrica es el tratamiento más efectivo para la pérdida de peso, con control de comorbilidades. Con bajas tasas de complicaciones, las razones para una reintervención pueden ser complicaciones mayores o falla/reganancia de peso. También se presentan problemas no quirúrgicos como anemia, deshidratación, dolor crónico y desnutrición, entre otros. El objetivo fue analizar las principales causas de cirugía revisional, reoperación y readmisión en un centro bariátrico de referencia. Métodos: Estudio retrospectivo de pacientes sometidos a cirugía bariátrica entre 2012 y 2019. Se realizó un análisis basal incluyendo datos demográficos, antropométricos y perioperatorios y un subanálisis con las principales indicaciones de readmisión y complicaciones. Resultados: Se realizaron 776 cirugías primarias (649 BPGYR, 127 MG y 10 cirugías de revisión), incluyendo 99 pacientes para el estudio: 10 de cirugía revisional, 44 reoperaciones y 45 readmisiones. La incidencia de cirugía revisional fue 1,2%, reoperación y readmisión 5,6% y 5,8% respectivamente. El 50% de las cirugías revisionales fue por pérdida insuficiente o reganancia de peso. Las causas más frecuentes de reoperación fueron: colecistitis (38.6%) y hernias internas (9.1%); las causas de readmisión más comunes fueron dolor abdominal inespecífico (35.5%) y deshidratación (24.4%). Conclusión: Las causas más frecuentes de readmisión poscirugía fueron enfermedades no quirúrgicas, seguido de reoperaciones no bariátricas y, finalmente, cirugías de revisión. Las reoperaciones tempranas por complicaciones tienen una incidencia baja. Es importante conocer lo previo para identificar a los pacientes con mayor riesgo y así prevenir complicaciones mayores.

During the concluding phase of the NASA Operation IceBridge (OIB), we successfully completed two airborne measurement campaigns (in 2018 and 2021, respectively) using a compact S and C band radar installed on a Single Otter aircraft and collected data over Alaskan mountains, ice fields, and glaciers. This paper reports seasonal snow depths derived from radar data. We found large variations in seasonal radar-inferred depths with multi-modal distributions assuming a constant relative permittivity for snow equal to 1.89. About 34 % of the snow depths observed in 2018 were between 3.2 and 4.2 m, and close to 30 % of the snow depths observed in 2021 were between 2.5 and 3.5 m. We observed snow strata in ice facies, combined percolation and wet-snow facies, and dry-snow facies from radar data and identified the transition areas from wet-snow facies to ice facies for multiple glaciers based on the snow strata and radar backscattering characteristics. Our analysis focuses on the measured strata of multiple years at the caldera of Mount Wrangell (K'elt'aeni) to estimate the local snow accumulation rate. We developed a method for using our radar readings of multi-year strata to constrain the uncertain parameters of interpretation models with the assumption that most of the snow layers detected by the radar at the caldera are annual accumulation layers. At a 2004 ice core and 2005 temperature sensor tower site, the locally estimated average snow accumulation rate is ∼2.89 m w.e. a−1 between the years 2003 and 2021. Our estimate of the snow accumulation rate between 2005 and 2006 is 2.82 m w.e. a−1, which matches closely to the 2.75 m w.e. a−1 inferred from independent ground-truth measurements made the same year. The snow accumulation rate between the years 2003 and 2021 also showed a linear increasing trend of 0.011 m w.e. a−2. This trend is corroborated by comparisons with the surface mass balance (SMB) derived for the same period from the regional atmospheric climate model MAR (Modèle Atmosphérique Régional). According to MAR data, which show an increase of 0.86 ∘C in this area for the period of 2003–2021, the linear upward trend is associated with the increase in snowfall and rainfall events, which may be attributed to elevated global temperatures. The findings of this study confirmed the viability of our methodology, as well as its underlying assumptions and interpretation models.

Neurological compression occurs in 10%–20% of patients who develop spinal metastases. In the last decade, the evolution of oncological diagnostic and medical techniques, the change from conventional external radiation to radiosurgery and the new surgical instruments have meant that the treatment of these patients must be indicated in a personalized manner and by consensus, multidisciplinary way, in specific commissions.Today, the biological state of the patient, the presence of mechanical instability, the neurological assessment and degree of epidural compression, as well as the best prognostic categorization of the tumor, are established as decision factors prior to the indication of surgical treatment, treatment that has passed from a cytoreductive concept to that of a spinal cord release from tumor in order to ensure safe radiosurgery. Resumen: La compresión neurológica se presenta entre el 10-20% de los pacientes que desarrollan una metástasis vertebral. En la última década, la evolución de las técnicas diagnósticas y médicas oncológicas, el cambio de la radiación convencional externa a la radiocirugía y los nuevos instrumentales quirúrgicos, han hecho que el tratamiento de estos pacientes deba de ser indicado de forma personalizada y en consenso, de forma multidisciplinar, en comisiones específicas.Hoy, el estado biológico del paciente, la presencia de inestabilidad mecánica, la valoración neurológica y el grado de compresión epidural, así como la mejor categorización pronóstica del tumor, se establecen como los factores de decisión previa a la indicación del tratamiento quirúrgico, tratamiento que ha pasado de un concepto «citorreductor» al de «separador» o «preparador» de la médula para asegurar una radiocirugía segura.

For some years now, the construction industry has been looking to improve productivity levels, reduce time and avoid cost overruns of the projects they perform; and has found a solution in BIM. In Mexico, the lack of national standards for the use of BIM makes it difficult to reach its potential. This research located different national strategies for BIM implementation world-wide; which were analyzed through a comparative analysis of qualitative content, in order to identify the various actions, and regulations that these countries have used to homogenize this implementation. The research concluded that the public and private sectors must create the con-ditions to promote implementing BIM, by creating criteria and standards related to the man-agement and delivery of the information in the projects, to successfully take advantage of this approach. The results will serve as support for the creation of a reference framework to imple-ment BIM in Mexico.

The crucial first step in the biodegradation of polyethylene plastic is oxidation of the polymer. This has traditionally required abiotic pre-treatment, but now Bertocchini and colleagues report two wax worm enzymes capable of catalyzing this oxidation and subsequent degradation at room temperature.

Abstract Alcohol is part of the usual diet of millions of individuals worldwide. However, not all individuals who drink alcohol experience the same effects, nor will everyone develop an alcohol use disorder. Here we propose that the intestinal microbiota (IMB) helps explain the different consumption patterns of alcohol among individuals. 507 humans participated in this study and alcohol consumption and IMB composition were analyzed. On the other hand, in 80 adult male Wistar rats, behavioral tests, alcohol intoxication, fecal transplantation, administration of antibiotics and collection of fecal samples were performed. For identification and relative quantification of bacterial taxa was used the bacterial 16 S ribosomal RNA gene. In humans, we found that heavy episodic drinking is associated with a specific stool type phenotype (type 1, according to Bristol Stool Scale; p

Abstract The 2021 Tajogaite eruption of Cumbre Vieja (La Palma, Spain) was typified by the emission of low viscosity lavas that flowed at high velocities and inundated a large area. We experimentally investigated the rheological evolution of melt feeding the eruption through concentric cylinder viscometry to understand the exceptional flowing ability of these lavas and constrain its emplacement dynamics. We conducted a set of cooling deformation experiments at different cooling rates (from 0.1 to 10 °C/min), and isothermal deformation experiments at subliquidus dwell temperatures between 1225 and 1175°C. All experiments were conducted at a shear rate of 10 s−1. Results show that disequilibrium crystallization and its timescale fundamentally control the rheological evolution of the melt, resulting in different rheological response to deformation of the crystal‐bearing magmatic suspension. Integrating rheological data with field observations allows us to shed light on the mechanisms that govern the high flowability of these lavas.

BACKGROUND AND OBJECTIVES: Atmospheric zinc corrosion in the Mexico City Metropolitan area has long been attributed mainly to the effect of pollutants such as sulfur dipxide. There are changes in the urban atmosphere's chemical composition due to the implementation of air quality policies focused on reducing the emission of sulfur dipxide and other pollutants. This study's objectives were to estimate and map the contribution of nitric acid on zinc's atmospheric corrosion process METHODS: The impact of nitric acid on zinc is feasible to estimate using a function for a multi-pollutant situation. This function contemplates the sum of two contributions: one of nitric acid and another that includes sulfuric acid and climatic parameters. The multi-pollutant function is suitable to apply in areas without the strong influence of chlorides and tropical and subtropical climates, comparable to the Mexico City Metropolitan area. FINDINGS: The results showed that spatial and temporal estimation of corrosion rates in grams per square meter of zinc was made for 2015-2019, using data modeling in a geographic information system. The maps of corrosion rates allowed us to visualize that, in general, the "southwest" zone has the most significant effects and that the lowest corrosion rates were presented in 2019 as an outcome of the implementation of air quality programs. Furthermore, a contribution of nitric acid up to 32% to the zinc corrosion rate was estimated. CONCLUSION: The construction of corrosion rate maps provides a spatial and temporal estimate that allows visualizing areas where zinc materials are at risk corrosion due to the dispersion of atmospheric pollutants and climatic parameters. Likewise, it can represent a decision-making tool for the implementation of atmospheric corrosion studies of materials. ==========================================================================================COPYRIGHTS©2021 The author(s). This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, as long as the original authors and source are cited. No permission is required from the authors or the publishers.==========================================================================================

Este trabajo presenta el modelado de un convertidor modular CC-CC basado en la conexión entrada serie - salida serie de dos celdas con convertidores con puentes duales activos. Esta configuración resulta interesante en aplicaciones en las cuales ambos puertos del convertidor deben soportar tensiones elevadas. A partir del análisis de las formas de onda de las principales variables eléctricas de cada una de las celdas, se obtienen las ecuaciones promediadas que permiten describir la dinámica del convertidor ante cambios significativos en las entradas de control del convertidor. El modelo promediado es linealizado entorno a un punto de funcionamiento del convertidor, obteniéndose dos sistemas de ecuaciones que permiten analizar la influencia de los parámetros constructivos de las celdas en el comportamiento estático y dinámico del convertidor. Los resultados obtenidos permiten validar en el dominio temporal los modelos obtenidos, tanto en régimen permanente como transitorio, en todo el rango de transferencia de potencia del convertidor.

Abstract This paper investigates whether the framework of fractional quantum mechanics can broaden our perspective of black hole thermodynamics. Concretely, we employ a space-fractional derivative (Riesz in Acta Math 81:1, 1949) as our main tool. Moreover, we restrict our analysis to the case of a Schwarzschild configuration. From a subsequently modified Wheeler–DeWitt equation, we retrieve the corresponding expressions for specific observables. Namely, the black hole mass spectrum, M, its temperature T, and entropy, S. We find that these bear consequential alterations conveyed through a fractional parameter, $$\alpha $$ α . In particular, the standard results are recovered in the specific limit $$\alpha =2$$ α = 2 . Furthermore, we elaborate how generalizations of the entropy-area relation suggested by Tsallis and Cirto (Eur Phys J C 73:2487, 2013) and Barrow (Phys Lett B 808:135643, 2020) acquire a complementary interpretation in terms of a fractional point of view. A thorough discussion of our results is presented.

Radar sounding of the thickness of temperate glaciers is challenged by substantial volume scattering, surface scattering and high attenuation rates. Lower-frequency radar sounders are often deployed to mitigate these effects, but the lack of a global synthesis of their success limits progress in system and survey design. Here we extend a recent global compilation of glacier thickness measurements (GlaThiDa) with the center frequency for radar-sounding surveys. From a maximum reported thickness of ∼ 1500 m near 1 MHz, the maximum thickness sounded decreases by ∼ 500 m per frequency decade. Between 25–100 MHz, newer airborne radar sounders generally outperform older, ground-based ones. Based on globally modeled glacier thicknesses, we conclude that a multi-element, ≤30 MHz airborne radar sounder could survey most temperate glaciers more efficiently.

Abstract Background Independent mobility (IM) provides young people with many opportunities to increase their autonomy and physical activity (PA). This study aimed to analyse whether the parent’s PA, active commuting to work and sociodemographic factors serve as predictors of IM to school in children and adolescents. Methods A total of 684 parents (52.8% mothers) and their offspring (56.4% girls) were included in this study, which was performed in Granada (Spain) and Valparaíso (Chile). The parents self-reported their sociodemographic characteristics, PA and mode of commuting to work. The mode of commuting to and from school and the offspring accompaniment mode were reported. T-test and chi-square test were used to study quantitative and qualitative differences by parental gender, respectively. Binary logistic regression models (odds ratio = OR) and stepwise analysis were performed to study the association between the parents’ sociodemographic variables and IM to school. Results Adolescents showed higher IM to school than children (58.9% vs 40.2%; p

Olive mill wastewater (OMW) is a complex effluent, with a high organic load and toxic compounds. Its seasonal production is an added difficulty for treatment systems. In this work, the heterogeneous Fenton process is used with low-cost catalysts, that are wastes rich in iron and other materials naturally present in nature, namely Red Mud (RM), the volcanic rocks of the Azores (VRA) and the volcanic rocks of the Canaries (VRC), to treat a mixture of five phenolic compounds usually present in OMW (3,4 - Dihydroxybenzoic, 4 - Hydroxybenzoic, 3,4 - Dimethoxybenzoic, 3,4,5 - Trimethoxybenzoic and Trans-cinnamic acids). The effect of adding hydrogen peroxide stepwise was also investigated and it was found that adding the oxidant at once is more efficient than the staged addition, for removing phenols as well as leading to less residual hydrogen peroxide. With regard to the utilization of low-cost catalysts, it was concluded that at the end of 60 min and for a concentration of 1 g/L of catalyst, the removal of phenolic content reaches 100% for RM, while in the case of VRA and VRC this value is 72.0% and 74.6%, respectively.

Abstract Background Lake Baikal is the largest body of liquid freshwater on Earth. Previous studies have described the microbial composition of this habitat, but the viral communities from this ecosystem have not been characterized in detail. Results Here, we describe the viral diversity of this habitat across depth and seasonal gradients. We discovered 19,475 bona fide viral sequences, which are derived from viruses predicted to infect abundant and ecologically important taxa that reside in Lake Baikal, such as Nitrospirota, Methylophilaceae, and Crenarchaeota. Diversity analysis revealed significant changes in viral community composition between epipelagic and bathypelagic zones. Analysis of the gene content of individual viral populations allowed us to describe one of the first bacteriophages that infect Nitrospirota, and their extensive repertoire of auxiliary metabolic genes that might enhance carbon fixation through the reductive TCA cycle. We also described bacteriophages of methylotrophic bacteria with the potential to enhance methanol oxidation and the S-adenosyl-L-methionine cycle. Conclusions These findings unraveled new ways by which viruses influence the carbon cycle in freshwater ecosystems, namely, by using auxiliary metabolic genes that act upon metabolisms of dark carbon fixation and methylotrophy. Therefore, our results shed light on the processes through which viruses can impact biogeochemical cycles of major ecological relevance. Video Abstract

Introduction: SARS-CoV-2 was first detected in December 2019 in the Chinese city of Wuhan and has since spread across the world. At present, the virus has infected over 1.7 million people and caused over 100 000 deaths worldwide. Research is currently focused on understanding the acute infection and developing effective treatment strategies. In view of the magnitude of the epidemic, we conducted a speculative review of possible medium- and long-term neurological consequences of SARS-CoV-2 infection, with particular emphasis on neurodegenerative and neuropsychiatric diseases of neuroinflammatory origin, based on the available evidence on neurological symptoms of acute SARS-CoV-2 infection. Development: We systematically reviewed the available evidence about the pathogenic mechanisms of SARS-CoV-2 infection, the immediate and lasting effects of the cytokine storm on the central nervous system, and the consequences of neuroinflammation for the central nervous system. Conclusions: SARS-CoV-2 is a neuroinvasive virus capable of triggering a cytokine storm, with persistent effects in specific populations. Although our hypothesis is highly speculative, the impact of SARS-CoV-2 infection on the onset and progression of neurodegenerative and neuropsychiatric diseases of neuroinflammatory origin should be regarded as the potential cause of a delayed pandemic that may have a major public health impact in the medium to long term. Cognitive and neuropsychological function should be closely monitored in COVID-19 survivors. Resumen: Introducción: La infección por el coronavirus SARS-CoV-2 originada en diciembre de 2019 en la región china de Wuhan ha adquirido proporciones pandémicas. A día de hoy ha ocasionado más de 1,7 millones de contagios y más de 100.000 muertes en todo el mundo. La investigación científica actual se centra en el mejor conocimiento de la infección aguda y de sus estrategias terapéuticas. Dada la magnitud de la epidemia, planteamos una revisión especulativa sobre las posibles consecuencias en patología neurológica a medio/largo plazo, con especial atención a enfermedades neurodegenerativas y neuropsiquiátricas con base neuroinflamatoria, teniendo en cuenta la evidencia directa de afectación neurológica a causa de la infección aguda. Desarrollo: Revisamos de forma sistemática lo conocido sobre los mecanismos patogénicos de la infección por SARS-CoV-2, la repercusión de la tormenta de citoquinas sobre el sistema nervioso central y su persistencia en el tiempo y las consecuencias que la neuroinflamación puede tener sobre el sistema nervioso central. Conclusiones: El SARS-CoV-2 es un virus neuroinvasivo capaz de provocar una tormenta de citoquinas que podría convertirse en persistente en población seleccionada. Aunque nuestra hipótesis tiene alto componente especulativo, la repercusión que esta situación puede tener en la puesta en marcha y progresión de enfermedades neurodegenerativas y neuropsiquiátricas con base neuroinflamatoria debe ser considerada como posible germen de una pandemia demorada que podría tener un gran impacto en salud pública a medio o largo plazo. Se hace necesario un estrecho seguimiento de la salud cognitiva y neuropsiquiátrica de los pacientes supervivientes a infección COVID-19.

Resumen: Introducción: La infección por el coronavirus SARS-CoV-2 originada en diciembre de 2019 en la región china de Wuhan ha adquirido proporciones pandémicas. A día de hoy ha ocasionado más de 1,7 millones de contagios y más de 100.000 muertes en todo el mundo. La investigación científica actual se centra en el mejor conocimiento de la infección aguda y de sus estrategias terapéuticas. Dada la magnitud de la epidemia, planteamos una revisión especulativa sobre las posibles consecuencias en patología neurológica a medio/largo plazo, con especial atención a enfermedades neurodegenerativas y neuropsiquiátricas con base neuroinflamatoria, teniendo en cuenta la evidencia directa de afectación neurológica a causa de la infección aguda. Desarrollo: Revisamos de forma sistemática lo conocido sobre los mecanismos patogénicos de la infección por SARS-CoV-2, la repercusión de la tormenta de citoquinas sobre el sistema nervioso central y su persistencia en el tiempo y las consecuencias que la neuroinflamación puede tener sobre el sistema nervioso central. Conclusiones: El SARS-CoV-2 es un virus neuroinvasivo capaz de provocar una tormenta de citoquinas que podría convertirse en persistente en población seleccionada. Aunque nuestra hipótesis tiene alto componente especulativo, la repercusión que esta situación puede tener en la puesta en marcha y progresión de enfermedades neurodegenerativas y neuropsiquiátricas con base neuroinflamatoria debe ser considerada como posible germen de una pandemia demorada que podría tener un gran impacto en salud pública a medio o largo plazo. Se hace necesario un estrecho seguimiento de la salud cognitiva y neuropsiquiátrica de los pacientes supervivientes a infección COVID-19. Abstract: Introduction: SARS-CoV-2 was first detected in December 2019 in the Chinese city of Wuhan and has since spread across the world. At present, the virus has infected over 1.7 million people and caused over 100 000 deaths worldwide. Research is currently focused on understanding the acute infection and developing effective treatment strategies. In view of the magnitude of the epidemic, we conducted a speculative review of possible medium- and long-term neurological consequences of SARS-CoV-2 infection, with particular emphasis on neurodegenerative and neuropsychiatric diseases of neuroinflammatory origin, based on the available evidence on neurological symptoms of acute SARS-CoV-2 infection. Development: We systematically reviewed the available evidence about the pathogenic mechanisms of SARS-CoV-2 infection, the immediate and lasting effects of the cytokine storm on the central nervous system, and the consequences of neuroinflammation for the central nervous system. Conclusions: SARS-CoV-2 is a neuroinvasive virus capable of triggering a cytokine storm, with persistent effects in specific populations. Although our hypothesis is highly speculative, the impact of SARS-CoV-2 infection on the onset and progression of neurodegenerative and neuropsychiatric diseases of neuroinflammatory origin should be regarded as the potential cause of a delayed pandemic that may have a major public health impact in the medium to long term. Cognitive and neuropsychological function should be closely monitored in COVID-19 survivors.

Alexandrium minutum blooms generally occur in semi-enclosed sites such as estuaries, harbours and lagoons, where enhanced stratification, restricted circulation and accumulation of resting cysts in the sediment set suitable habitat conditions for the proliferation of this paralytic shellfish poisoning toxigenic species. In the Galician Rías Baixas (NW Iberian Peninsula), according to weekly time-series between 1994 and 2020, blooms of A. minutum were recurrent in small, shallow estuarine bays inside the Rías de Vigo and Pontevedra, but rarely detected, and if so at low concentrations, out of these environments. However, from May to July 2018 it developed as usual in the small inner bays but then spread over both Rías (Vigo and Pontevedra) causing discoloured waters during one month and prolonged harvesting closures. Meteorological conditions during that period (rains / runoff higher than climatological averages, sustained temperature increment and oscillating wind pattern –i.e., series of upwelling-relaxation cycles), fostered optimal circumstances for the development of that extensive and massive proliferation: strong vertical stratification and the alternation of retention and dispersion processes. Simulations from a particle tracking model portrayed the observed bloom development phases: onset and development inside a small inner bay; transport within the surface layer, from these sites towards the interior parts of the Ría; and dispersion all over the embayment. Seedbeds with high concentrations of resting cysts were detected several months after the bloom, which may have favoured flourishment of A. minutum in the following two years, markedly in 2020. The present work contributes to the general understanding of the dynamics of harmful algal blooms (HABs), from which surveillance indicators of the state of marine ecosystems and their evolution can be derived. We hypothesize that the intensity and frequency of A. minutum proliferations in the Galician Rías could increase under projected climate trends.

ABSTRACT In summer 2019, a large, bright pink microbial mat was visible on top of macroalgal deposits in muddy sediments of an urban beach (Playa do Adro, Vigo). In order to characterize the dominant organisms in these colored mats, results from microscopic observations, photosynthetic pigments, and molecular analysis were gathered. Light microscopy examination revealed pinkish microbial aggregates with minor contributions of larger protists and cyanobacteria. High-performance liquid chromatography (HPLC) pigment analysis documented the dominance of bacteriochlorophyll a and carotenoids whose spectra were compatible with those described in photosynthetic purple bacteria. 16S rRNA gene amplicon sequencing confirmed that the vast majority of reads belonged to Proteobacteria (73.5%), and among them, nearly 88% of those reads belonged to purple sulfur bacteria (Gammaproteobacteria). A single family, Chromatiaceae, constituted the bulk of this assemblage, including the genera Thiohalocapsa (32%), Marichromatium (12.5%), Phaeochromatium (5%), and Halocromatium (2%) as main contributors. Nonetheless, a considerable number of sequences could not be assigned to a particular genus, stressing the large biological diversity in these microbial mats and the potential presence of novel taxa of purple sulfur bacteria. IMPORTANCE Urban beaches are valuable recreational areas particularly vulnerable to human disturbance. In these areas, the intertidal sediments harbor a diverse community of microorganisms, including virus, bacteria, fungi, and protozoa. In this sense, pollution events can introduce pathogenic allochthonous microbes which may constitute a human health risk. Visual and sensory observations, such as a weird color or bad smell, are usually appreciated as a warning by beachgoers and authorities, as indeed was the case at do Adro beach in 2019. The observed proliferation seems to be common in summertime, but its dimension alerted beachgoers and media. The obtained results allowed for the identification of purple sulfur bacteria as responsible for the pink-violet top layer staining the intertidal zone. These blooms have never been associated with public health risks. Beyond solving the sanitary concern, other important findings were its diversity and large proportion of novel taxa, illustrating the complexity of these ecosystems.