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INTRODUCTION: Hernias, particularly groin hernias, are prevalent surgical pathologies worldwide, often necessitating surgery in cases of complications. This study investigates the safety and efficacy of performing bilateral inguinal hernioplasty when one side faces complications, addressing the lack of consensus in emergency groin hernia treatment. MATERIALS AND METHODS: A retrospective, single-center study spanning a duration of 10 years was conducted, including adult patients who underwent emergency surgery for inguinal hernia. Propensity score matching was employed to create similar groups for comparative analysis of unilateral versus bilateral emergency groin hernioplasty. Surgical techniques, complications, mortality, and long-term outcomes were evaluated. RESULTS: This study included 341 patients. Data obtained from the study revealed high morbidity and 90-day mortality rates, consistent with the data of existing literature. Propensity score matching yielded two comparable groups. Short-term outcomes showed no significant differences in complication rates, mortality, surgical site infection, or hospital stay between unilateral and bilateral hernioplasty groups. Bilateral surgery takes approximately 15 min of the procedure time. Long-term outcomes exhibited similar recurrence rates between groups. CONCLUSION: This study supports the practice of bilateral inguinal hernioplasty in emergency scenarios when one side faces complications. It is a safe approach without any significant increase in morbidity or hospital stay, while reducing the need for a subsequent intervention and its associated risks and costs. Further prospective research is necessary to confirm these findings.

We propose a new SU(6)⊗U(1)X GUT model free from anomalies, with a 750 GeV scalar candidate which can decay into two photons, compatible with the recent diphoton signal reported by ATLAS and CMS collaborations. This model gives masses to all fermions and may explain the 750 GeV signal through one loop decays to γγ with charged vector and charged Higgs bosons, as well as up- and electron-like exotic particles that arise naturally from the condition of cancellation of anomalies of the SU(6)⊗U(1)X group. We obtain, for different width approximations, allowed mass regions from 900 GeV to 3 TeV for the exotic up-like quark, in agreement with ATLAS and CMS collaborations data.

El uso de esteroide está reconocido en el tratamiento crítico del paciente quemado y es útil en el choque séptico que no responde a vasopresores. Este grupo de medicamentos ayuda a regular la respuesta hemodinámica mejorando el aporte de sangre a la piel, aunque sabemos que tienen un efecto nocivo en el proceso de cicatrización. Evaluamos el efecto histopatológico del empleo de esteroides en quemaduras usando un modelo animal. Empleamos 2 grupos de 10 ratas (Wistar) en las que colocamos un cilindro de metal en el dorso durante 15 segundos a 95ºC, produciendo una quemadura. En ese momento, uno de los grupos recibió esteroide a dosis de estrés (hidrocortisona 5 mg/kg) y el otro no recibió ningún medicamento. Al quinto día resecamos la escara y cubrimos el defecto con cultivo de queratinocitos. Los animales fueron sacrificadas a los 14 días. Realizamos análisis histopatológico. Macroscópicamente evaluamos la presencia de infección y el porcentaje de epitelización. Microscópicamente evaluamos la fibrosis, la inflamación, la presencia de fibroblastos y la proliferación vascular. Comparamos ambos grupos usando la prueba de Chi² (SPSS versión 10). Consideramos como significativo un valor p=/< 05. No encontramos ningún dato de infección en ninguno de los 2 grupos de estudio. El sitio de la quemadura estaba epitelizado al 100% en el día 14. No encontramos diferencia en fibrosis (p .47), proceso inflamatorio (p.27) y presencia de fibroblastos (p.16). Encontramos diferencia en proliferación vascular (p .05), lo cual puede implicar una diferencia en el proceso de cicatrización en contra del primer grupo, en el que se emplearon los esteroides sistémicos. En conclusión, encontramos diferencia en la proliferación vascular en contra del grupo de esteroides, lo cual puede tener un efecto negativo en el proceso de cicatrización. Aunque es más importante mantener un paciente vivo, sobre todo en caso de choque séptico que no responde a vasopresores, no estamos seguros de qué consecuencia puede tener este hallazgo en la formación de sinequias o en la contracción de la herida a largo plazo.The use of steroids is well recognized in critical care specially in septic shock. There are some reports of their utility in severe burns. It helps to regulate the hemodynamic response in order to improve the blood supply to the skin, although it is well known their negative effect in wound healing. Our objective is to know the hystopathologic effect of steroids in burn healing. We used 2 groups of 10 rats (Wistar). Both groups were exposed in their backs to a metallic cylinder at 95 ºC for 15 seconds. At the moment of the burn, one group was given steroid (hydrocortisone at stress dose 5 mg/kg) and the other group didn't received any medication. The scar was removed at the 5th day and the burn injury was covered with queratinocyte culture. The rats were sacrificed at 14th day. We evaluated the presence of clinical signs of infection and the percentage of new epithelium. In the microscope we evaluated the following parameters: fibrosis, inflammatory process, presence of fibroblast and vascular proliferation. We compared both groups using Chi² test (SPSS program version 10). A p =/

Missing or unavailable data (NA) in multivariate data analysis is often treated with imputation methods and, in some cases, records containing NA are eliminated, leading to the loss of information. This paper addresses the problem of NA in multiple factor analysis (MFA) without resorting to eliminating records or using imputation techniques. For this purpose, the nonlinear iterative partial least squares (NIPALS) algorithm is proposed based on the principle of available data. NIPALS presents a good alternative when data imputation is not feasible. Our proposed method is called MFA-NIPALS and, based on simulation scenarios, we recommend its use until 15% of NAs of total observations. A case of groups of quantitative variables is studied and the proposed NIPALS algorithm is compared with the regularized iterative MFA algorithm for several percentages of NA.

LoRaWAN is a long range and low power protocol devised for connecting devices under the Internet of Things (IoT) paradigm. This protocol was not conceived to support real-time message delivery; therefore, it is not always feasible using it to support IoT solutions involving large wireless sensors networks and time constraint messaging, e.g., in early warning systems for natural hazards, remote monitoring of industrial machinery or autonomous control of transportation systems. This paper presents a model that provides certainty, at the design time of IoT systems, about the real-time communication capability of their supporting network. It allows solution designers: (1) to decide if developing or not a real-time IoT solution based on the feasibility of its communication infrastructure, and (2) to improve the communication infrastructure to try making real-time communication feasible using LoRaWAN.

LoRaWAN has become the most widely used low-power wide-area network technology to implement monitoring solutions based on the Internet of remote things (IoRT) paradigm. Typically, these solutions interconnect remote sensing areas and data processing infrastructure located in urban centers. The operation expenses of these solutions depend mainly on the traffic sent through the network backhaul, i.e., the link that connects the remote sensing area and the urban area where the data are usually processed and stored. This service is provided by telecommunication companies and represents the main operation cost of IoRT solutions. These expenses usually limit the affordability of IoRT-based systems in developing countries, and also in scenarios where the operational cost is an issue to address. This paper presents an extension to the LoRaWAN protocol, named Node-Aware-LoRaWAN (NA-LoRaWAN), that reduces the traffic in the backhaul, thus decreasing the operational expenses of IoRT-based systems. In order to evaluate the performance of NA-LoRaWAN, it was compared to a regular LoRaWAN implementation. Depending on the network scenario, the proposed extension reduced the traffic through the backhaul in the range of 12–34%. This extension opens several opportunities to use IoRT solutions in application domains with a low operational budget, e.g., precision agriculture, environmental monitoring and natural hazards’ early detection.