1. Oedema, Starling and Pulse Reverse Osmosis: Towards a Possible Biochemical Marker for Oedema
- Author
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T. Gourlay, Kenneth M. Taylor, V. Morecroft, R. Fergusson, and F. G. R. Prior
- Subjects
medicine.medical_specialty ,biology ,Pulse (signal processing) ,business.industry ,Starling ,Biomedical Engineering ,Medicine (miscellaneous) ,Bioengineering ,Osmotic gradient ,General Medicine ,030204 cardiovascular system & hematology ,biology.organism_classification ,Surgery ,Biomaterials ,03 medical and health sciences ,0302 clinical medicine ,Blood pressure ,030228 respiratory system ,Interstitial fluid ,Internal medicine ,Healthy volunteers ,medicine ,Cardiology ,Arterial blood ,business - Abstract
Several conflicting theories have been proposed to explain the devlopment of oedema. Pulse reverse osmosis (PRO) suggests that oedema occurs when the mean pulse capillary pressure exceeds the osmotic gradient between the plasma and the interstitial fluid. In order to test this concept mean arterial blood pressures and colloid osmotic pressures were taken in a group of healthy volunteers, a group of patients with bilateral ankle oedema and a group of treated hypertensives. Patients with oedema were found to have colloid osmotic pressures (COP's) which were significantly less than those of the healthy volunteers (p
- Published
- 1999
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