Search

Patient-therapist matching was investigated using recent theoretical and methodological developments to overcome some of the limitations that have hindered similar past efforts. Two hypotheses were tested: (a) Therapeutic outcome is affected by the interaction between patients' and therapists' self-concepts, and (b) increasing anticomplementarity between therapist self-concept and therapists' perceptions of patients' behavior is negatively associated with patient improvement. Data from the first 2 cohorts of the Vanderbilt II Psychotherapy Project were analyzed. They included the therapies of 16 experienced therapists, who saw a total of 48 patients (38 women and 10 men) in time-limited psychotherapy. Patients' ages ranged from 24 to 64 years (M age = 40). Outcome was measured from the perspective of the patient, therapist, and evaluating clinician. Each hypothesis was supported, but not across all 3 outcome perspectives.

Test by ultracentrifugation and moving boundary electrophoresis of the effects of incremental oxidation on urania sols showed that the resulting U (VI) (at least from 14 to 25% oxidation of 0.02 M sol) neither diffuses throughout the U02 crystallites nor forms a surface layer on them, but goes into the aqueous solution. Changes in ionic strength, due mainly to changing U(VI) concentration in solution produced either by the oxidation of U(IV) or by addition of U(VI), were calculated and found to correlate well with the zeta potentials determined from the electrophoretic mobilities of the colloid particles. Comparisons with a theoretical model of colloid particle interaction showed that the range of zeta potentials is consistent with the observed effects on viscosity and stability of the sols.

In a population of 64 patients with cancer of the prostate, 5 of them showed thromboembolic episodes after treatment with Diethyl Stilbestrol (DES) however no thromboembolic complication in patients treated with 17 bèta oestradiol (17βE2) was observed. Predisposing factors to thromboembolism were examined in untreated patients and in the same patients separated in two randomized groups after three months of treatment with either DES or 17βE2.Before treatment no significant modifications of coagulation factors platelet count, platelet functions, anti Till, plasminogen and fibrinogen levels were observed when compared to a control population of the same age. It was also established that lipids, triglycerides (TG) and very low density lipoproteins (VLDL) were normal before treatment.After treatment, thromboembolic episodes were only observed in the group receiving DES. Although no modifications of platelets and coagulation factors were observed, a significant increase in TG and VLDL was found. In contrast in the 29 patients treated with 17βE2 no thromboembolic complication of either the coagulation profile or TG and VLDL levels was found.It is concluded therefore that the elevation of TG and VLDL was the only difference observed between patients treated with either DES or 17βE2. It is however unclear from our study how these parameters influence the coagulation process.It is proposed that other dynamic coagulation investigations have to be performed in order to assume the role of TG and VLDL predisposing factors to thromboembolism.