568 results on '"F, Lemaire"'
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2. Analysis of plasmaspheric plumes: CLUSTER and IMAGE observations
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F. Darrouzet, J. De Keyser, P. M. E. Décréau, D. L. Gallagher, V. Pierrard, J. F. Lemaire, B. R. Sandel, I. Dandouras, H. Matsui, M. Dunlop, J. Cabrera, A. Masson, P. Canu, J. G. Trotignon, J. L. Rauch, and M. André more...
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Science ,Physics ,QC1-999 ,Geophysics. Cosmic physics ,QC801-809 - Abstract
Plasmaspheric plumes have been routinely observed by CLUSTER and IMAGE. The CLUSTER mission provides high time resolution four-point measurements of the plasmasphere near perigee. Total electron density profiles have been derived from the electron plasma frequency identified by the WHISPER sounder supplemented, in-between soundings, by relative variations of the spacecraft potential measured by the electric field instrument EFW; ion velocity is also measured onboard these satellites. The EUV imager onboard the IMAGE spacecraft provides global images of the plasmasphere with a spatial resolution of 0.1 RE every 10 min; such images acquired near apogee from high above the pole show the geometry of plasmaspheric plumes, their evolution and motion. We present coordinated observations of three plume events and compare CLUSTER in-situ data with global images of the plasmasphere obtained by IMAGE. In particular, we study the geometry and the orientation of plasmaspheric plumes by using four-point analysis methods. We compare several aspects of plume motion as determined by different methods: (i) inner and outer plume boundary velocity calculated from time delays of this boundary as observed by the wave experiment WHISPER on the four spacecraft, (ii) drift velocity measured by the electron drift instrument EDI onboard CLUSTER and (iii) global velocity determined from successive EUV images. These different techniques consistently indicate that plasmaspheric plumes rotate around the Earth, with their foot fully co-rotating, but with their tip rotating slower and moving farther out. more...
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- 2006
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Catalog
3. Density structures inside the plasmasphere: Cluster observations
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F. Darrouzet, P. M. E. Décréau, J. De Keyser, A. Masson, D. L. Gallagher, O. Santolik, B. R. Sandel, J. G. Trotignon, J. L. Rauch, E. Le Guirriec, P. Canu, F. Sedgemore, M. André, and J. F. Lemaire
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Science ,Physics ,QC1-999 ,Geophysics. Cosmic physics ,QC801-809 - Abstract
The electron density profiles derived from the EFW and WHISPER instruments on board the four Cluster spacecraft reveal density structures inside the plasmasphere and at its outer boundary, the plasmapause. We have conducted a statistical study to characterize these density structures. We focus on the plasmasphere crossing on 11 April 2002, during which Cluster observed several density irregularities inside the plasmasphere, as well as a plasmaspheric plume. We derive the density gradient vectors from simultaneous density measurements by the four spacecraft. We also determine the normal velocity of the boundaries of the plume and of the irregularities from the time delays between those boundaries in the four individual density profiles, assuming they are planar. These new observations yield novel insights about the occurrence of density irregularities, their geometry and their dynamics. These in-situ measurements are compared with global images of the plasmasphere from the EUV imager on board the IMAGE satellite. more...
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- 2004
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4. The synthetic biology toolkit for photosynthetic microorganisms[OPEN]
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Vavitsas, K. Crozet, P. Vinde, M.H. Davies, F. Lemaire, S.D. Vickers, C.E.
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- 2019
5. Inhaled nitric oxide for acute chest syndrome in adult sickle cell patients: a randomized controlled study
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A. Charles-Nelson, François Lionnet, A. Mekontso Dessap, Frédéric Galactéros, I. Bourgeon, Muriel Fartoukh, Mehdi Khellaf, Michel Djibré, Sandrine Katsahian, Anoosha Habibi, Bernard Maitre, K. Stankovic Stojanovic, C. Brun-Buisson, Laurent Brochard, and F. Lemaire more...
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Adult ,Male ,medicine.medical_specialty ,Anemia, Sickle Cell ,Nitric Oxide ,Critical Care and Intensive Care Medicine ,Placebo ,law.invention ,Hypoxemia ,Young Adult ,Double-Blind Method ,Randomized controlled trial ,law ,Internal medicine ,Acute Chest Syndrome ,Administration, Inhalation ,medicine ,Clinical endpoint ,Humans ,Prospective Studies ,Prospective cohort study ,Endothelium-Dependent Relaxing Factors ,business.industry ,Odds ratio ,Phlebotomy ,medicine.disease ,Acute chest syndrome ,Anesthesia ,Cardiology ,Female ,medicine.symptom ,business - Abstract
Previous clinical trials suggested that inhaled nitric oxide (iNO) could have beneficial effects in sickle cell disease (SCD) patients with acute chest syndrome (ACS). To determine whether iNO reduces treatment failure rate in adult patients with ACS, we conducted a prospective, double-blind, randomized, placebo-controlled clinical trial. iNO (80 ppm, N = 50) gas or inhaled nitrogen placebo (N = 50) was delivered for 3 days. The primary end point was the number of patients with treatment failure at day 3, defined as any one of the following: (1) death from any cause, (2) need for endotracheal intubation, (3) decrease of PaO2/FiO2 ≥ 15 mmHg between days 1 and 3, (4) augmented therapy defined as new transfusion or phlebotomy. The two groups did not differ in age, gender, genotype, or baseline characteristics and biological parameters. iNO was well tolerated, although a transient decrease in nitric oxide concentration was mandated in one patient. There was no significant difference in the primary end point between the iNO and placebo groups [23 (46 %) and 29 (58 %); odds ratio (OR), 0.8; 95 % CI, 0.54–1.16; p = 0.23]. A post hoc analysis of the 45 patients with hypoxemia showed that those in the iNO group were less likely to experience treatment failure at day 3 [7 (33.3 %) vs 18 (72 %); OR = 0.19; 95 % CI, 0.06–0.68; p = 0.009]. iNO did not reduce the rate of treatment failure in adult SCD patients with mild to moderate ACS. Future trials should target more severely ill ACS patients with hypoxemia. NCT00748423. more...
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- 2015
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6. Le traitement de l’insuffisance respiratoire aiguë par l’oxygénation extracorporelle au moyen d’un oxygénateur à membrane (ECMO) : les origines
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F. Lemaire
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business.industry ,medicine.medical_treatment ,Oxygenation ,Emergency Nursing ,Extracorporeal ,law.invention ,Randomized controlled trial ,law ,medicine.artery ,Anesthesia ,Emergency Medicine ,Extracorporeal membrane oxygenation ,Breathing ,Medicine ,Acute respiratory failure ,business ,Bronchial artery ,Perfusion - Abstract
Extracorporeal membrane oxygenation (ECMO) applied to acute respiratory distress syndrome was clinically used as soon as the early seventies. A large randomized trial sponsored by the US National Institute of Health failed to show superiority over conventional treatment, i.e. mechan‑ ical ventilation with positive end‑expiratory pressure. Mor‑ tality was high (95%) in both arms. Venoarterial bypass was the most commonly used route for perfusion at that time. Overall complications were common, some of them deadly: hemolysis, bleeding, hypo‑ or hyper‑coagulation, superinfections, lower limb ischemia, lack of oxygena‑ tion of coronary and bronchial arteries… Large utilization stopped after the ECMO trial results were published in JAMA, in 1979. During the eighties, L. Gattinoni and col‑ laborators renewed the rationale of extracorporeal support and started to implement what was called "low frequency positive pressure ventilation with extracorporeal CO 2 removal", with much better results. more...
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- 2013
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7. Coronal Temperature Profiles Obtained from Kinetic Models and from Coronal Brightness Measurements Obtained During Solar Eclipses
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V. Pierrard, K. Borremans, K. Stegen, and J. F. Lemaire
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Physics ,Brightness ,Astrophysics::High Energy Astrophysical Phenomena ,FOS: Physical sciences ,Astronomy and Astrophysics ,Astrophysics ,Kinetic energy ,Corona ,Solar wind ,Astrophysics - Solar and Stellar Astrophysics ,Heat flux ,13. Climate action ,Space and Planetary Science ,Coronal plane ,Physics::Space Physics ,Astrophysics::Solar and Stellar Astrophysics ,Polar ,Astrophysics::Earth and Planetary Astrophysics ,Chromosphere ,Solar and Stellar Astrophysics (astro-ph.SR) - Abstract
Coronal density, temperature and heat flux distributions for the equatorial and polar corona have been deduced by Lemaire [2012] from Saito's model of averaged coronal white light (WL) brightness and polarization observations. They are compared with those determined from a kinetic collisionless/exospheric model of the solar corona. This comparison indicates rather similar distributions at large radial distances (> 7 Rs) in the collisionless region. However, rather important differences are found close to the Sun in the acceleration region of the solar wind. The exospheric heat flux is directed away from the Sun, while that inferred from all WL coronal observations is in the opposite direction, i.e., conducting heat from the inner corona toward the chromosphere. This could indicate that the source of coronal heating rate extends up into the inner corona where it maximizes at r > 1.5 Rs well above the transition region., 11 pages, 1 figure, A comparison between Exospheric Model and a Hybrid model of the corona based on white light eclipse observations more...
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- 2013
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8. Analytical Control of a Starter Pig Feed Medicated with Amoxicillin
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F. Lemaire, M. Zemanová, A. Sanquer, Z. Haas, A. Hera, E. Bousquet, and J. Maxa
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Active ingredient ,Analytical control ,lcsh:Veterinary medicine ,Chromatography ,General Veterinary ,Chemistry ,pelletization ,Starter pig ,assay ,Amoxicillin ,Pelletizing ,Microbiology ,Beta-lactam ,chemistry.chemical_compound ,Starter ,medicine ,piglet ,lcsh:SF600-1100 ,Beta-lactams ,medication ,medicine.drug - Abstract
Zemanova M., J. Maxa, A. Hera, Z. Haas, F. Lemaire, A. Sanquer, E. Bousquet: Analytical Control of a Starter Pig Feed Medicated with Amoxicillin. Acta Vet. Brno 2008, 77: 341-345. Amoxicillin concentrations were determined by two independent laboratories for a pig starter feed medicated from a coated amoxicillin premix. The analytical method was previously transferred from one laboratory to the other one. The data between the two laboratories were consistent, showing ruggedness of the assay. Mean amoxicillin feed concentrations before and after pelletization were higher than 90% of the theoretical content, confirming satisfactory stability of this active ingredient in the coated form tested. more...
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- 2008
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9. Committee for the Protection of Persons
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Nathalie Brion, Jean-Paul Demarez, Chantal Belorgey, P. Amiel, F. Berger, C. Bernaud, N. Best, I. Brindel, F. Chapuis, M. Couderc, S. Courcier Duplantier, F. De Crémiers, A. Deneulin, V. Diebolt, T. Dupin Spriet, C. Funck Brentano, J. Genève, C. Guérin, A. Guillardeau Jaillon, S. Hansel, S. Hilaly, P. Lechat, F. Lemaire, F. Loeb, G. Loeb, A. Mijonnet, J. Moret Bailly, C. Nourissier, C. Oréfice, J.-M. Laurent Vo, Y. Plétan, T. Roche, P. Sassano, C. Sibenaler, and B. White Gay more...
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Clinical trial ,Round table ,Order (business) ,business.industry ,Law ,Good clinical practice ,Authorization ,Declaration ,Medicine ,Pharmacology (medical) ,Legislation ,business ,Directive - Abstract
The transposition into French law of Directive 2001/20/CE, which relates to good clinical practice in the conduction of trials on drugs for human use, has required the modification of certain provisions that concern the protection of persons participating in biomedical research, in particular those provisions concerning the conditions for the authorisation of biomedical research. Declaration to the competent authorities now comes prior to authorisation and, henceforth, the prior opinion of a Committee for the Protection of Persons (CPP) must be expressly favourable in order for a trial to be undertaken. Proposals are put forward by this Round Table in order to promote the stability and professionalism of the CPPs. more...
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- 2005
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10. Comité de Protection des Personnes
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Nathalie Brion, Jean-Paul Demarez, Chantal Belorgey, P. Amiel, F. Berger, C. Bernaud, N. Best, I. Brindel, F. Chapuis, M. Couderc, S. Courcier Duplantier, F. De Crémiers, A. Deneulin, V. Diebolt, T. Dupin Spriet, C. Funck Brentano, J. Genève, C. Guérin, A. Guillardeau Jaillon, S. Hansel, S. Hilaly, P. Lechat, F. Lemaire, F. Loeb, G. Loeb, A. Mijonnet, J. Moret Bailly, C. Nourissier, C. Oréfice, J.-M. Laurent Vo, Y. Plétan, T. Roche, P. Sassano, C. Sibenaler, and B. White Gay more...
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Pharmacology (medical) - Abstract
Resume La transposition de la directive 2001/20/CE relative aux bonnes pratiques cliniques dans la conduite des essais de medicaments a usage humain a necessite la modification de certaines dispositions du droit francais en matiere de protection des personnes se pretant a des recherches biomedicales, notamment celles relatives aux conditions d’autorisation des recherches biomedicales. Le regime declaratif a l’autorite competente anterieur devient un regime d’autorisation prealable, et l’avis prealable d’un comite de protection a desormais la necessite d’etre expressement favorable pour que l’essai soit mis en œuvre. Des propositions sont formulees par cette table ronde afin de favoriser la stabilite et le professionnalisme des Comites de Protection des Personnes (CPP). more...
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- 2005
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11. Temperature measurement in AlGaN/GaN High-Electron-Mobility Transistors using micro-Raman scattering spectroscopy
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R. Aubry, M.-A. DiForte-Poisson, Christian Dua, P. Galtier, Sylvain Delage, B. Dessertenne, Jean-Claude Jacquet, F. Lemaire, and Yvon Cordier
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Electron mobility ,Silicon ,Chemistry ,business.industry ,Thermal resistance ,Analytical chemistry ,chemistry.chemical_element ,Gallium nitride ,Semiconductor device ,High-electron-mobility transistor ,Condensed Matter Physics ,Temperature measurement ,Electronic, Optical and Magnetic Materials ,chemistry.chemical_compound ,symbols.namesake ,symbols ,Optoelectronics ,business ,Instrumentation ,Raman scattering - Abstract
High power RF device performance decreases as operation temperature increases (e.g. decreasing electron mobility affects cut-off frequencies and degrades device reliability). Therefore determination of device temperature is a key issue for device topology optimisation. In this work the temperature variation of AlGaN/GaN high-electron-mobility transistors grown either on silicon or sapphire substrate under bias operation was measured by micro Raman scattering spectroscopy. Temperature measurements up to power dissipation of 16 W for 4 mm development devices were carried out and a peak temperature of 650 K was determined. The difference of thermal resistance for similar devices grown on the two different substrates was assessed. The thermal resistances of different device topologies were compared to optimise the component design. more...
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- 2005
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12. Temperature measurement by micro-Raman scattering spectroscopy in the active zone of AlGaN/GaN high-electron-mobility transistors
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M.-A. DiForte-Poisson, R. Aubry, Christian Dua, P. Galtier, Jean-Claude Jacquet, Yvon Cordier, B. Dessertenne, Sylvain Delage, and F. Lemaire
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Electron mobility ,Chemistry ,business.industry ,Thermal resistance ,Analytical chemistry ,Gallium nitride ,Semiconductor device ,High-electron-mobility transistor ,Condensed Matter Physics ,Temperature measurement ,Electronic, Optical and Magnetic Materials ,chemistry.chemical_compound ,Temperature gradient ,symbols.namesake ,symbols ,Optoelectronics ,business ,Instrumentation ,Raman scattering - Abstract
The high power RF device performance decreases as the operation temperature increases (e.g. fall of electron mobility impacting the cut-off frequencies and degradation of device reliability). Therefore the determination of device temperature is a key issue for device topology optimisation. In this work the temperature variation of AlGaN/GaN high-electron-mobility transistors grown either on silicon or sapphire substrates under bias operation was measured by micro Raman scattering spectroscopy. The differences in thermal resistance for similar devices grown on the two different substrates were assessed. The thermal resistances of different device topologies were compared in order to optimise the component design. The temperature measurement across the gate and along the component fingers were made to quantify the thermal gradient of the device. Temperature measurement up to a power dissipation of 16 W for a 4 mm development device was carried out and the peak temperature of 650 K was determined. more...
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- 2004
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13. Loss of HOP tumour suppressor expression in head and neck squamous cell carcinoma
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Bohdan Wasylyk, L. Bracco, Danièle Muller, F Lemaire, Y. Rabouel, Régine Millon, and Joseph Abecassis
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Cancer Research ,Pathology ,medicine.medical_specialty ,Tumor suppressor gene ,Cellular differentiation ,Biology ,Hop (networking) ,law.invention ,Hypopharyngeal Carcinoma ,law ,Biomarkers, Tumor ,medicine ,Humans ,Genes, Tumor Suppressor ,RNA, Messenger ,development ,In Situ Hybridization ,Homeodomain Proteins ,Reverse Transcriptase Polymerase Chain Reaction ,Tumor Suppressor Proteins ,Molecular and Cellular Pathology ,hypopharynx ,Cell Differentiation ,differentiation ,Blotting, Northern ,medicine.disease ,Head and neck squamous-cell carcinoma ,Epithelium ,medicine.anatomical_structure ,homeodomain ,Oncology ,Epidermoid carcinoma ,Head and Neck Neoplasms ,Carcinoma, Squamous Cell ,Suppressor - Abstract
We report that homeodomain-only protein (HOP) is expressed in the suprabasal layer of normal upper aerodigestive tract epithelium and expression strongly decreases in hypopharyngeal carcinoma. Interestingly, HOP has very recently been shown to be a tumour suppressor involved in differentiation, suggesting that HOP may have a similar role in head and neck squamous cell carcinoma (HNSSC). more...
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- 2004
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14. Controverse autour des essais sur la réduction du volume courant au cours du SDRASmall vs large tidal volume in ARDS: the controversy
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F Lemaire
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Intensive care ,Political science ,Emergency Medicine ,Emergency Nursing ,Humanities - Abstract
Resume L’ARDS Network, un reseau de services de reanimation nord-americains finances par le NIH et comprenant maintenant une quarantaine de services/unites de reanimation affilies a l’American Thoracic Society, a produit la celebrissime etude Vt 6 vs Vt 12 ml/kg dans le SDRA. Apres la publication des resultats de cette etude dans le New England Journal of Medicine (NEJM), l’ARDS Network a entrepris un nouvel essai randomise dans le SDRA, comparant cette fois la restriction hydrique a un remplissage genereux, le FACCT trial. Mais, en 2002, deux medecins du NIH, les Drs Eichacker et Natanson, publiaient une meta-analyse des cinq essais randomises qui s’etaient attaques a ce probleme et notaient que la modalite ventilatoire du groupe temoin utilisee dans l’article du NEJM (12 ml/kg) ne correspondait pas au standard — bien inferieur — utilise a l’epoque ou l’essai avait ete conduit : ils accusaient les chercheurs de l’ARDS Network d’avoir manipule les resultats de leur etude et surtout d’avoir soumis les patients de ce groupe temoin a des risques injustifies. Cette mise en cause a conduit un bureau federal responsable de la surveillance des essais cliniques, l’OHRP, a demander des explications aux investigateurs de l’ARDS Network. Dans l’attente des resultats de cette enquete, le NIH, promoteur des activites du reseau, decidait un moratoire sur les activites de l’ARDS Network, interrompant ainsi l’essai FACCT, qui avait pourtant deja recrute plus de 400 patients, et coute quelques millions de dollars. Les investigateurs de l’ARDS Network et les autorites du NIH se sont mobilises contre cette decision. Une serie d’articles du NEJM et une correspondance fournie de l’ American Journal of Respiratory and Critical Care Medicine ont temoigne de l’âprete des debats qui se sont alors deroules aux Etats-Unis. A la suite d’une conference d’experts organisee par le ministere de la sante nord-americain, l’ARDS Network a ete autorise a reprendre l’essai interrompu, a la condition que les formulaires d’information « patients » soient reecrits de facon a etre plus explicites sur les risques de l’essai et qu’ils precisent mieux ce qui est experimental et ce qui reste du domaine du soin courant ( standard of care ). Meme si la controverse est (transitoirement ?) eteinte, les questions qu’elle a soulevees ne le sont certainement pas : le consentement a la recherche des patients incapables, la separation claire entre le soin et la recherche, l’ecrasante preeminence des essais randomises controles, le role de la presse scientifique… more...
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- 2004
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15. La loi Jardé sur la recherche impliquant la personne humaine : qu’apportera-t-elle aux investigateurs ?
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F. Lemaire
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Anesthesiology and Pain Medicine ,General Medicine - Published
- 2013
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16. Le refus de transfusion sanguine en réanimationRefusal of blood transfusion in intensive care
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F Lemaire
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Intensive care ,Recien nacido ,Philosophy ,Emergency Medicine ,Emergency Nursing ,Humanities ,Autotransfusion - Abstract
Resume Il n’y a pas de geste plus banal en reanimation que la transfusion d’erythrocytes. Les Temoins de Jehovah (TJ) la refusent, l’interdiction de la transfusion sanguine etant centrale dans leur doctrine. Les besoins de transfusion ont ete recemment revus a la baisse en reanimation, a la suite de l’etude de Paul Hebert publiee en 1999 dans le New England Journal of Medicine . Meme si l’avenir de la transfusion est clairement domine par l’emploi des substituts de l’hemoglobine, il faut insister sur ce qu’aucun de ces produits ne peut aujourd’hui etre utilise en routine pour traiter une anemie aigue. Il existe certainement une tendance en France depuis quelques annees a exiger que les medecins obtiennent le consentement des patients avant de les traiter. Cette obligation du respect de leur volonte est inscrite dans la loi « soins palliatifs » de 1999 et renforcee dans la loi « Droits des patients » de mars 2002. Neanmoins, le juge administratif, saisi en refere au cours de l’ete 2002, n’a pas exige des medecins qu’ils laissent mourir des TJ en « risque vital » sans les transfuser. Meme si pour l’instant la juridiction administrative a son echelon le plus eleve (le Conseil d’Etat) semble avoir « rectifie » la loi, le dilemme ethique reste insoluble pour les reanimateurs confrontes a ce probleme : sauver la vie de ces patients au prix de leur espoir de vie eternelle, ou respecter leur volonte et laisser mourir des malades aisement guerissables… more...
- Published
- 2003
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17. Public Information about Clinical Trials and Research
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Yannick Plétan, Faïez Zannad, Patrice Jaillon, E. Autret-Leca, Ch. Belorgey, M. Bernard-Harlaut, D. Cellier, F. Chazelle, M.F. Chevallier-Le Guyader, M. Couderc, D. Debiais, J. D’Enfert, A.M. Duguet, L. Fleury, M. Gallard, A. Giacomino, Y. Juillet, H. Kolsky, J.P. Lehner, F. Lemaire, M.F. Padioleau, M. Peschanski, S. Ravoire, J.P. Reynier, Ph. Ricordeau, P. Sassano, C. Sibenaler, M.C. Simon, and J. Soletti more...
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medicine.medical_specialty ,Medical education ,Public information ,business.industry ,education ,Alternative medicine ,Charter ,Social security ,Clinical trial ,Clinical research ,Medicine ,Pharmacology (medical) ,business ,Good practice ,health care economics and organizations ,Pharmaceutical industry - Abstract
Be it to restore the confused image of clinical research in relation to the lay public, or to develop new ways of accruing healthy volunteers or patients for clinical trials, there is a need to draft some guidance on how best to provide information on research. Although the French legal and regulatory armamentarium in this area is essentially liberal, there is currently little-justified reluctance among study sponsors to advertise publicly. A group of academic and pharmaceutical industry researchers, assembled for a workshop, together with regulators, journalists, representatives from ethics committees, social security, patient and health consumer groups and other French institutional bodies, has suggested the following series of recommendations: – there is no need for additional legal or regulatory constraints; – sponsors should be aware of and make use of direct public information on trials; – a ‘good practice charter’ on public communication about clinical trials should be developed; – all professionals should be involved in this communication platform; – communication in the patient’s immediate vicinity should be preferred (primary-care physician, local press); – clinical databases and websites accessible to professionals, but also to patients and non-professionals, should be developed; – genuine instruction on clinical trials for physicians and health professionals unfamiliar with such trials should be developed and disseminated; – media groups should receive at least some training in the fundamentals of clinical research. more...
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- 2003
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18. Sur l’encadrement législatif des recherches biomédicales chez l’homme, à l’occasion de la transposition dans le droit français de la directive européenne
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Jacques Rouëssé, P. Banzet, J. Civatte, F. Darnis, J. Dubousset, R. Küss, H. Laccourreye, B. Launois, J.D. Picard, C. Sureau, G. Blaudin de Thé, P. Tiollais, M. Tubiana, M. Verhaeghe, Messieurs A. Aurengo, J. Bazex, G. Dubois, H. Rochefort, J. Rouëssé, Madame V. Daurat, MM.M. Genève, null Henry-Amar, F. Lemaire, null Maraninchi, J. Ménard, and J. Michaud more...
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Political science ,General Medicine ,Humanities - Abstract
RESUME L’Academie Nationale deMedecine considere que la recherche biomedicale, chez l’homme, respectant les regles de l’ethique medicale et de la rigueur scientifique, est un imperatif de Sante Publique. Son encadrement legislatif est necessaire. L’Academie s’inquiete de l’insuffisance de la participation francaise dans cette recherche. Celle-ci doit etre encouragee et les contraintes injustifiees qui pesent, en particulier, sur les etudes dont le but est l’accroissement des connaissances, independantes de l’Industrie, doivent etre levees. La participation a de telles recherches doit etre un critere de qualite pris en compte dans l’evaluation des etablissements de soins ayant vocation de recherche clinique, mais leur cout doit etre reconnu. L’Academie approuve le projet de supprimer la distinction entre les recherches avec ou sans benefice individuel direct. Elle constate, avec satisfaction, que la directive europeenne concernant la recherche biomedicale, chez l’homme, ne fait pas rentrer dans son champ les etudes ne concernant pas des innovations therapeutiques mais souhaite que leur definition soit precisee afin de lever toute ambiguite. La publication des resultats des recherches, meme negatifs, lui parait indispensable. Celle-ci doit etre rapide, si elle comporte des consequences sur la Sante Publique. A l’inverse, elle souhaite que soient evitees les informations prematurees et non validees. La creation d’un registre national des essais et des enquetres epidemiologiques est une necessite. La representation du patient incapable de consentir doit etre precisee par la loi et chez l’enfant, un desaccord des parents sur l’autorisation de participation de leur enfant devrait emporter refus. Le fonctionnement des comites consultatifs pour la protection des personnes (CCPPRB) devrait etre optimise. La charge de travail impliquee par la participation aux reunions de ces comites doit etre reconnue. La possibilite de creer des comites nationaux specialises (en genetique, cancerologie, pediatrie...), dont les CCPPRB devraient pouvoir solliciter les avis, devrait etre envisagee. Les decisions des CCPPRB devraient pouvoir faire l’objet d’un appel devant une structure nationale. La dimension europeenne etant indispensable a la realisation d’un grand nombre d’etudes, l’harmonisation des legislations des pays de la Communaute est une necessite ; elle doit amener a la ceation d’une structure d’appel europeenne dans ce domaine. more...
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- 2003
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19. Relationships between growing media fertility, percolate composition and fertigation strategy in peat-substitute substrates used for growing ornamental shrubs
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Francesco Giuffrida, Oriol Marfà, Vincent Guérin, Rafaela Cáceres, and F. Lemaire
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0106 biological sciences ,Fertigation ,biology ,Compost ,04 agricultural and veterinary sciences ,15. Life on land ,Horticulture ,engineering.material ,biology.organism_classification ,01 natural sciences ,Manure ,6. Clean water ,Nutrient ,040103 agronomy & agriculture ,engineering ,Perlite ,0401 agriculture, forestry, and fisheries ,Environmental science ,Viburnum tinus ,Coir ,Euonymus japonicus ,010606 plant biology & botany - Abstract
The composition of root-zone solution of container grown Viburnum tinus L. ‘Eve Price’, Nerium oleander L. ‘Emile Shaut’ and Euonymus japonicus Thunb. were studied in two different localities (France and Spain). The growing media assayed were binary mixtures prepared with Finnish sphagnum peat, the following peat-substitutes: cattle manure compost, forest waste compost, pine bark compost, yard compost and raw coir. Perlite was used as inorganic amendment in one mixture. The composition of the root-zone solution was monitored by the induced percolate (IP) method and the applied nutrient solution (NS) was modulated by dilution in the experiments carried out in the French location or by increasing the volume applied to manage the electrical conductivity in the experiments conducted in the Spanish location. Modulation of the NS–water ratio resulted in a linear relation of percolate composition to NS composition. That relation was not present when the NS was not diluted. The results indicate that a steady-state nutrient level in the root zone can be achieved when a modulated and relatively low concentration of NS is applied by fertigation. Release of nutrients, especially nitrates, occurs during growing period. The biostability of the substrates and the initial availability of phosphorus and potassium determine the composition of the leachates. The results proved that the IP method can be used to monitor nutrient levels in the root zone and its use can enhance the nutrient-use efficiency in commercial nurseries. more...
- Published
- 2002
- Full Text
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20. Growth of Viburnum tinus in peat-based and peat-substitute growing media
- Author
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Vincent Guérin, Oriol Marfà, Francesco Giuffrida, Rafaela Cáceres, and F. Lemaire
- Subjects
Peat ,biology ,Compost ,Drip irrigation ,Horticulture ,engineering.material ,biology.organism_classification ,Manure ,Ornamental plant ,engineering ,Perlite ,Environmental science ,Viburnum tinus ,Coir - Abstract
To assess the growth of ornamental shrubs in peat alternative substrates, one ornamental species, Viburnum tinus L., was cultivated in a number of different substrates in two climates: a French oceanic (Oce) and a Spanish Mediterranean (Med). In Oce, three mixtures (1/1, v/v) of Finnish peat/yard compost, yard compost/raw coir and Finnish peat/raw coir were used while the expanded perlite/composted manure (1/1), forest compost/composted bark (1/1) and forest compost/cattle manure compost (2/3) were tested in Med. A mixture (1/1) of Finnish peat/pine bark compost was used in both climates as a control. Plants were cultivated at a density of six plants/m 2 in 4 l containers with drip irrigation. Plant height, dry mass, and leaf area were measured at intervals during cultivation. In Oce, substrates with yard compost or raw coir produced plants of similar size to those in the control substrate. In Med, forest compost/cattle manure compost mixture produced plants with the same height as those in the control mixture and the two other mixtures produced shorter plants. In both climates, substrates ranked the same whether height, dry mass or leaf area were considered. Using those parameters, significant effects of different substrates were revealed. Those effects are related to the substrate characteristics, mainly physical ones. As peat is used in a large range of situations, the experiment showed that substrate performance varies with its use, so alternative substrates can show better performance than those using peat. more...
- Published
- 2001
- Full Text
- View/download PDF
21. Recherche clinique en réanimation: problèmes liés à l'application de la loi du 20 décembre 1988
- Author
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S. Rameix, A. Langlois, H. Outin, and F. Lemaire
- Subjects
Political science ,Critical Care and Intensive Care Medicine - Published
- 2000
- Full Text
- View/download PDF
22. Limitations et arrêts de traitements actifs en réanimation: un autre point de vue
- Author
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F. Lemaire
- Subjects
business.industry ,Medicine ,Critical Care and Intensive Care Medicine ,business - Published
- 2000
- Full Text
- View/download PDF
23. Ventilator-associated lung injury in ARDS
- Author
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J. Russell, A. Slutsky, F. Lemaire, G. Ramsay, J. Mancebo, C. Richard, J. Marini, Ch. Brun-Buisson, J. Carlet, D. Cook, G. Dobb, J. Hall, R. Hubmayr, R. Rodriguez-Roisin, J. Takala, and M. Tobin
- Subjects
ARDS ,Ventilator-associated lung injury ,business.industry ,Anesthesia ,medicine ,Critical Care and Intensive Care Medicine ,medicine.disease ,business - Published
- 2000
- Full Text
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24. CONSEQUENCES OF USING ALTERNATIVE TO PEAT SUBSTRATES FOR THE ENVIRONMENT
- Author
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Francesco Giuffrida, F. Lemaire, Rafaela Cáceres, Oriol Marfà, and Vincent Guérin
- Subjects
Pollution ,Peat ,Agroforestry ,media_common.quotation_subject ,Horticulture ,Agronomy ,visual_art ,Ornamental plant ,Perlite ,visual_art.visual_art_medium ,Environmental science ,Cultural methods ,Bark ,Water use ,Woody plant ,media_common - Published
- 2000
- Full Text
- View/download PDF
25. A new case of 'complete' trisomy 5p with isochromosome 5p associated with a de novo translocation t(5;8)(q11;p23)
- Author
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R. Casanova, M. Fujita, F. Lemaire, E. Flori, and D. Astruc
- Subjects
Male ,congenital, hereditary, and neonatal diseases and abnormalities ,Centromere ,Isochromosome ,Chromosome Disorders ,Trisomy ,Chromosomal translocation ,Biology ,Translocation, Genetic ,Fatal Outcome ,Genetics ,medicine ,Humans ,Abnormalities, Multiple ,Genetics (clinical) ,Chromosome Aberrations ,Partial Trisomy ,Infant ,Telomere ,medicine.disease ,Molecular biology ,Chromosome Banding ,Isochromosomes ,Karyotyping ,Chromosomes, Human, Pair 5 ,Chromosomes, Human, Pair 8 - Abstract
A boy with a de novo translocation t(5;8)(q11;p23) and an isochromosome 5p is described. The main clinical features found in the complete trisomies 5p are reviewed and the mechanisms of the chromosomal rearrangements involving centromeric and telomeric regions are discussed. more...
- Published
- 2008
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26. Le consentement aux soins en réanimation
- Author
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E. Roupie, F. Lemaire, and S. Rameix
- Subjects
Critical Care and Intensive Care Medicine ,Psychology - Published
- 1997
- Full Text
- View/download PDF
27. THE PROBLEM OF THE BIOSTABILITY IN ORGANIC SUBSTRATES
- Author
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F. Lemaire, Sciences Agronomiques Appliquées à l'Horticulture (SAGAH), Université d'Angers (UA)-Institut National de la Recherche Agronomique (INRA)-Institut National d'Horticulture, ProdInra, Migration, and Institut National d'Horticulture-Institut National de la Recherche Agronomique (INRA)-Université d'Angers (UA) more...
- Subjects
[SDV] Life Sciences [q-bio] ,[SDE] Environmental Sciences ,0106 biological sciences ,[SDV]Life Sciences [q-bio] ,[SDE]Environmental Sciences ,040103 agronomy & agriculture ,0401 agriculture, forestry, and fisheries ,Environmental science ,04 agricultural and veterinary sciences ,Horticulture ,01 natural sciences ,ComputingMilieux_MISCELLANEOUS ,010606 plant biology & botany - Abstract
International audience
- Published
- 1997
- Full Text
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28. Informed consent for research purposes in intensive care patients in Europe - part II
- Author
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F. Lemaire, L. Blanch, S. L. Cohen, and C. Sprung
- Subjects
Critical Care and Intensive Care Medicine - Published
- 1997
- Full Text
- View/download PDF
29. Quelle(s) définition(s) pour le syndrome de détresse respiratoire aiguë ?
- Author
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F. Jardin and F. Lemaire
- Subjects
business.industry ,Emergency Medicine ,Medicine ,Emergency Nursing ,business - Published
- 2005
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- View/download PDF
30. Waiving consent for emergency research
- Author
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F. Lemaire
- Subjects
Research ethics ,Emergency research ,business.industry ,Informed consent ,Clinical Biochemistry ,Medicine ,General Medicine ,Medical emergency ,Emergency treatment ,business ,medicine.disease ,Biochemistry - Published
- 2005
- Full Text
- View/download PDF
31. What Happens When the Geomagnetic Field Reverses?
- Author
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S. F. Singer and J. F. Lemaire
- Subjects
Physics ,Geomagnetic storm ,Solar energetic particles ,Cosmic ray ,Astrophysics ,Physics::Geophysics ,symbols.namesake ,Earth's magnetic field ,Van Allen radiation belt ,Physics::Space Physics ,symbols ,Astrophysics::Earth and Planetary Astrophysics ,Interplanetary magnetic field ,Magnetic dipole ,Ring current - Abstract
During geomagnetic field reversals the radiation belt high-energy proton populations become depleted. Their energy spectra become softer, with the trapped particles of highest energies being lost first, and eventually recovering after a field reversal. The radiation belts rebuild in a dynamical way with the energy spectra flattening on the average during the course of many millennia, but without ever reaching complete steady state equilibrium between successive geomagnetic storm events determined by southward turnings of the IMF orientation. Considering that the entry of galactic cosmic rays and the solar energetic particles with energies above a given threshold are strongly controlled by the intensity of the northward component of the interplanetary magnetic field, we speculate that at earlier epochs when the geomagnetic dipole was reversed, the entry of these energetic particles into the geomagnetic field was facilitated when the interplanetary magnetic field was directed northward. Unlike in other complementary work where intensive numerical simulations have been used, our demonstration is based on a simple analytical extension of Stormer's theory. The access of GCR and SEP beyond geomagnetic cut-off latitudes is enhanced during epochs when the Earth's magnetic dipole is reduced, as already demonstrated earlier. more...
- Published
- 2013
- Full Text
- View/download PDF
32. Myélinolyse centro-pontine révélée par une monoplégie supérieure gauche sans hyponatrémie ni dénutrition
- Author
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C. Kpade, J.-F. Lemaire, C. Magni, I. Durieu, J. Limodin, and M. Paulin
- Subjects
Neurology ,Neurology (clinical) - Abstract
Resume De mecanisme etiopathogenique non elucide, la myelinolyse centro-pontine affecte la portion centrale de la base du pont. Elle est frequemment causee par une correction rapide d’une hyponatremie et se manifeste principalement par une tetraparesie spastique, un syndrome bulbaire voire un « locked-in syndrome ». Nous rapportons un cas de myelinolyse centro-pontine revelee par une monoplegie superieure gauche, sans hyponatremie chez une femme de 40 ans alcoolique mais qui ne presenta aucun signe de denutrition. Cette myelinolyse centro-pontine fut consecutive a une tentative de suicide polymedicamenteuse associee a une prise d’alcool a 90°. Le diagnostic fut confirme par l’imagerie cerebrale. L’interet de cette observation reside dans le caractere pauci-symptomatique des manifestations cliniques et l’absence de trouble ionique et nutritionnel. more...
- Published
- 2004
- Full Text
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33. [Jardé law on human research: what's new for the investigators?]
- Author
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F, Lemaire
- Subjects
Europe ,Biomedical Research ,Stem Cells ,Humans ,France ,Research Personnel - Published
- 2013
34. PHYSICAL, CHEMICAL AND BIOLOGICAL PROPERTIES OF GROWING MEDIUM
- Author
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F. Lemaire, ProdInra, Migration, Sciences Agronomiques Appliquées à l'Horticulture (SAGAH), Université d'Angers (UA)-Institut National de la Recherche Agronomique (INRA)-Institut National d'Horticulture, and Institut National d'Horticulture-Institut National de la Recherche Agronomique (INRA)-Université d'Angers (UA) more...
- Subjects
[SDE] Environmental Sciences ,0106 biological sciences ,Chemistry ,[SDV]Life Sciences [q-bio] ,health care facilities, manpower, and services ,education ,Nanotechnology ,04 agricultural and veterinary sciences ,Horticulture ,01 natural sciences ,STABILITE ,[SDV] Life Sciences [q-bio] ,surgical procedures, operative ,Biological property ,Physical chemical ,[SDE]Environmental Sciences ,040103 agronomy & agriculture ,0401 agriculture, forestry, and fisheries ,health care economics and organizations ,010606 plant biology & botany - Abstract
Hydroponics and transplant production; International audience
- Published
- 1995
- Full Text
- View/download PDF
35. La commission éthique de la SRLF : pourquoi faire ?Role of the SRLF Ethical Commitee
- Author
-
F Lemaire
- Subjects
Political science ,Emergency Medicine ,Commission ,Emergency Nursing ,Humanities - Abstract
La commission ethique de la SRLF a deja 20 ans. Lors du vingtieme anniversaire du comite consultatif national d’ethique, en mars 2003 au college de France, la question a ete posee de l’interet et des missions possibles des commissions ethiques de societes savantes. Un rapide bilan a cette occasion a revele qu’une dizaine de societes savantes francaises avaient ou etaient en train de constituer une commission, un comite ou un groupe ad hoc d’ethique. Mais la question n’excluait pas un certain scepticisme : n’y a t-il pas un risque de vouloir doubler des structures existantes et legitimes (CCNE, CCPPRB) ? Une inquietude aussi quant a la legitimite de telles structures ? L’experience de la commission ethique de la SRLF (CE–SRLF) permet certainement de repondre a ces questions. Quelles en sont donc les missions ? La premiere tâche d’une commission ethique de societe savante est sans doute de mener une reflexion sur les problemes — moraux, deontologiques, medico-legaux... bref, ethiques — qui se posent a nos disciplines : les difficultes du consentement, l’acharnement therapeutique, la fin de vie en reanimation, l’information des familles, la responsabilite, la legitimite de la recherche sur des malades inconscients, les possibles conflits d’interet, etc. C’est sans doute cette premiere mission qui sous-tend l’ensemble de ses autres activites. Une autre mission importante de la CE–SRLF est sa participation a la formation des reanimateurs par son implication dans la preparation du congres national annuel. La commission ethique de la societe de reanimation de langue francaise (SRLF) prepare et anime un « cas clinique » d’ethique chaque annee : un accident — mortel — de la recherche en 2000 [1] ; le refus de la transfusion sanguine par un temoin de Jehovah en 2001 (c’etait plus d’un an avant l’« affaire » de Valenciennes [2] !) ; l’arret de la nutrition et de l’hydratation dans un cas d’etat vegetatif (Herve Mal et Philippe Gajdos) en 2002. Ces seances remplissent habituellement une salle de taille moyenne. En 2002, la CE–SRLF avait aussi organise une reunion de formation continue d’une journee consacree a la fin de vie en reanimation. De facon similaire, la societe europeenne de reanimation (ESICM) confie a sa commission ethique le soin de lui proposer « cle en main » trois seances thematiques pour son congres annuel. L’organisation de sessions thematiques lors des congres de la discipline permet de sensibiliser les reanimateurs aux problemes ethiques ; il y a la un formidable outil de formation et d’amelioration des pratiques dans nos services. more...
- Published
- 2003
- Full Text
- View/download PDF
36. The effect of a southward interplanetary magnetic field on St\'ormer's allowed regions
- Author
-
Joseph F. Lemaire
- Subjects
Physics ,Atmospheric Science ,Mathematics::Operator Algebras ,Aerospace Engineering ,Astronomy and Astrophysics ,Cosmic ray ,Astrophysics ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Charged particle ,Magnetic field ,symbols.namesake ,Dipole ,Geophysics ,Earth's magnetic field ,Physics - Space Physics ,Space and Planetary Science ,Van Allen radiation belt ,Physics::Space Physics ,symbols ,General Earth and Planetary Sciences ,Interplanetary magnetic field ,Magnetic dipole ,Astrophysics - Earth and Planetary Astrophysics - Abstract
The motion of a charged particle in a magnetic dipole has first been studied by Stormer. The different applications of Stormer's theory to aurorae, cosmic rays and Van Allen radiation belt particles are recalled in an historical perspective. In this paper, we expand the Stormer theory in order to take into account the effects produced by an additional uniform and stationary interplanetary magnetic field (IMF) whose orientation is parallel or antiparallel to the magnetic moment of the dipole. A new expression is derived for the Stormer potential taking into account the additional IMF component. It is shown how Stormer's allowed and forbidden zones are influenced by the implementation of a northward or a southward IMF, and how a southward turning of the IMF orientation makes it easier for Solar Energetic Particle and Galactic Cosmic Rays to enter into the inner part of the geomagnetic field along interconnected magnetic field lines., Comment: 24 Pages; 15 Figures; Tutorial Lecture Presented At The Cospar Colloquium "Plasma Processes In Th Near-Earth Space: Interball And Beyond, Sofia, Bulgaria, 5-10 2002 more...
- Published
- 2012
37. [From Huriet law to Jardé law]
- Author
-
F, Lemaire and M, Matei
- Subjects
Respiratory Therapy ,Biomedical Research ,Informed Consent ,Patient Rights ,Humans ,Legislation, Hospital ,Observation ,France ,Therapeutic Human Experimentation - Published
- 2012
38. Le syndrome de detresse respiratorie aigue de l’an 2000
- Author
-
F. Lemaire, SERVILLO, GIUSEPPE, Lemaire F - Masson, F., Lemaire, and Servillo, Giuseppe
- Published
- 2000
39. NITROGEN FORM AND SUSCEPTIBILITY OF PELARGONIUM X HORTORUM TO XANTHOMONAS
- Author
-
B. Digat and F. Lemaire
- Subjects
Horticulture ,chemistry ,Xanthomonas ,Pelargonium x hortorum ,Botany ,chemistry.chemical_element ,Biology ,biology.organism_classification ,Nitrogen - Published
- 1993
- Full Text
- View/download PDF
40. SANITARY IMPROVEMENT OF FOUR ORNAMENTAL SHRUBS : CONSEQUENCES FOR THE YIELD AND THE MINERAL CONTENT OF THE BIOMASS
- Author
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F. Lemaire, ProdInra, Migration, Sciences Agronomiques Appliquées à l'Horticulture (SAGAH), Université d'Angers (UA)-Institut National de la Recherche Agronomique (INRA)-Institut National d'Horticulture, and Institut National d'Horticulture-Institut National de la Recherche Agronomique (INRA)-Université d'Angers (UA) more...
- Subjects
[SDE] Environmental Sciences ,2. Zero hunger ,Materials science ,[SDV]Life Sciences [q-bio] ,Biomass ,15. Life on land ,Horticulture ,[SDV] Life Sciences [q-bio] ,Agronomy ,Yield (wine) ,[SDE]Environmental Sciences ,Ornamental plant ,ComputingMilieux_MISCELLANEOUS - Abstract
National audience
- Published
- 1992
- Full Text
- View/download PDF
41. Acute/Chronic respiratory failure II
- Author
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H. Georges, N. Gueteau, O. Leroy, C. Santré, C. Beuscart, H. Medaoui, C. Lemaire, G. Beaucaire, I. Cabezas, H. Romo, E. Salazar, M. Narváez, D. Pinquier, G. Boussignac, D. Pavlovic, M. Aubier, F. Beaufils, J. C. Raphael, F. Bouvet, S. Chevret, Cl. Chastang, R. Boiteou, T. Lherm, F. Marcier, F. Chamieh, D. Perrin, A. Tenaillon, J. M. Gabillet, B. Guidet, F. Staikowsky, G. Offenstadt, P. Amstutz, C. Truchero, J. Moya, A. Diaz-Prieto, F. Konrad, R. Schiener, J. Kilian, M. Georgieff, F. Salord, V. Cayrel, A. Peloux, S. Tixier, R. Chacornac, A. Durocher, A. M. Durocher, C. Gires, L. Behr, F. Saulnier, L. Gruez, F. Boileau, Ph. Dewailly, H. Wiedeck, R. Boiteau, D. Perrin-Gachadoat, E. Valente, H. Hmouda, A. Fatrane, L. Fakhfakh, N. Bloch, B. Rousset, J. H. Boix, J. Marin, A. Amau, M. Tejeda, D. Olivares, E. Servera, M. Dambrosio, M. Dojat, D. Touchard, A. Harf, F. Lemaire, L. Brochard, C. Tormo, V. Lópes, V. Parra, R. Calvo, V. Lacueva, J. L. Maravall, A. Carneiro, B. Huet, C. Brun-Buisson, A. J. Schneider, A. B. J. Groeneveld, L. G. Thijs, R. I. C. Wesdorp, B. Lafon, M. Denis, T. Vassal, C. Mayaud, M. Högman, H. Hedenström, C. Frostell, H. Arnberg, G. Hedenstierna, J. -A. Romand, M. R. Pinsky, L. Firestone, J. R. Lancaster, H. Zar, F. Brunet, M. Belghith, J. P. Mira, J. J. Lanore, B. Renaud, F. Pochard, J. F. Vaxelaire, I. Hamy, A. Armaganidis, J. Dall’ava, J. F. Dhainaut, P. Navalesi, F. Maltais, A. Gursahanev, P. Hernandez, M. Sovili, S. Gottfried, L. Gregorakos, C. Katsanos, V. Malessios, J. Nicoiopoulos, L. Tsaldari, M. Kountouri, M. T. Martín, F. J. Santos, S. Iribarren, A. Fernández, G. Diaz-Regañón, Ch Martínez, Yu. Sirenko, O. Sychev, M. Shchupak, L. Babiy, J. Muñoz, F. Ruiz, J. Blanquer, M. Simó, A. Herrejón, C. Núñez, E. Chiner, S. Nouira, S. Elatrous, A. Bchir, M. Jaafoura, F. Abroug, S. Bouchouha, S. Bahrami, Y. Yu, H. Redl, G. Schlag, G. Conti, A. Cogliati, D. Dell’Utri, A. Ferretti, R. Traversa, L. Di Chiara, P. Marino, J. Kesecioĝlu, J. C. Pompe, I. Gültuna, C. Ince, W. Erdmann, H. A. Bruining, J. Castañeda, J. Blanco, C. Aldecoa, T. Boulain, Y. Furet, P. F. Dequin, A. Legras, and D. Perrotin more...
- Subjects
Critical Care and Intensive Care Medicine - Published
- 1992
- Full Text
- View/download PDF
42. Acute/Chronic respiratory failure III
- Author
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E. Fernàndez Mondèjar, G. Vazquez Mata, F. Ferròn, P. Navarrete, J. M. Torres Ruiz, P. Lestavel, L. Tronchon, M. C. Chambrin, J. Mangalaboyi, A. Rime, C. Chopin, P. Valta, R. Campodonico, C. Corbeil, M. Chassè, A. Châtillon, J. Braidy, N. Matar, J. Milic-Emili, J. Lòpez-Messa, L. Penas, A. Valverde, M. Dambrosio, E. Roupie, A. Carneiro, M. C. Anglade, N. Vasile, L. Brochard, F. Lemaire, J. Rubio, M. S. Carrasco, I. Mateo, R. Sierra, A. Escolar, J. Cozar, K. Bastin, R. Knapen, J. J. Moraine, C. Melot, R. Sergysels, R. J. Kahn, P. Pelosi, M. Cereda, G. Foti, L. D’Andrea, B. Manetti, A. Lissoni, A. Pesenti, J. M. Allegue Gallego, J. A. Gòmez Rubi, C. Palazòn Sànchez, A. Melgarejo Moreno, T. Lherm, R. Boiteau, E. Valente, M. Beaussier, F. Chamieh, A. Tenaillon, E. R. Righini, R. Alvisi, R. Ragazzi, C. A. Volta, M. Capuzzo, G. Gritti, M. Sydow, H. Burchardi, J. Zinserling, T. A. Crozier, J. Guttmann, L. Eberhard, W. Bertschmann, B. Fabry, G. Wolff, A. Rubini, D. D. DelMonte, V. Catena, I. Attar, G. Rattazzi, G. L. Alati, M. Arias Diaz, G. Vàzquez Mata, P. Navarrete Navarro, F. Guerrero Lòpez, A. Mèrida Morales, J. Isenegger, L. Picazo, A. Sanchez, B. Hernandez, A. Pons, G. Conti, L. Di Chiara, R. A. De Blasi, D. Dell’Utri, A. Cogliati, P. Pelaia, A. Ferretti, F. Bernasconi, G. Banfi, C. Putensen, G. Putensen-Himmer, M. Leon, P. E. M. Huygen, I. Gültuna, A. Zwart, C. Ince, H. A. Bruining, J. C. Pompe, J. Kesecioĝlu, A. Rabbat, J. P. Laaban, E. Orvoen-Frija, A. Achkar, J. Rochemaure, V. Frigo, M. Solca, G. Melloni, C. Gerbsa, A. Ornaghi, S. Mancini, R. Cavagnoli, W. Fasano, C. Santos, J. Roca, A. Torres, J. Cardùs, J. A. Barberà, M. A. Felez, R. Rodriguez-Roisin, R. Oviedo-Moreira, L. Beydon, G. Nakos, A. Precates, C. Mathas, N. Bassilakis, K. Chagianagnostou, L. Massoura, S. Labropoulos, M. Devroey, P. Vansnick, C. Mèlot, R. Naeije, V. Nagy, R. Kiiski, S. Kaitainen, R. Karppi, J. Takala, J. Kesecioglu, W. Erdmann, J. Marin, A. Arnau, M. Tejeda, D. Olivares, E. Servera, J. H. Boix, F. Alvarez, F. Peydro, J. P. Mira, M. Belghith, B. Renaud, E. Deland, F. Brunet, A. Brusset, J. J. Lanore, I. Hamy, J. L. Termignon, O. Soubrane, F. Pochard, J. F. Dhainaut, P. S. Sidhu, J. F. Cockburn, D. A. Nicholson, A. Kennedy, P. Dawson, and F. E. Servera more...
- Subjects
Critical Care and Intensive Care Medicine - Published
- 1992
- Full Text
- View/download PDF
43. Acute/Chronic respiratory failure
- Author
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A. Carneiro, A. Harf, D. Touchard, H. Zar, F. Chamieh, E. Chiner, E. Servera, S. Bouchouha, Michael R. Pinsky, M. Simó, A. Ferretti, J. Blanco, F. Marcier, M. Denis, O. Sychev, G. Conti, E. Salazar, R. Boiteou, M. Belghith, C. Tormo, A. Durocher, H. Hmouda, C. Frostell, C. Aldecoa, M. Tejeda, R. Chacornac, L. Di Chiara, G. Schlag, P. Hernandez, I. Cabezas, S. Iribarren, L. Fakhfakh, J. R. Lancaster, E. Valente, Michael Georgieff, F. Staikowsky, L. Gregorakos, A. Amau, Stewart B. Gottfried, F. Beaufils, C. Santré, S. Nouira, F. Ruiz, A. Bchir, L. Behr, S. Tixier, M. T. Martín, F. Bouvet, C. Núñez, V. Lacueva, N. Bloch, C. Beuscart, C. Katsanos, G. Beaucaire, J. Dall’ava, A. Fatrane, V. Malessios, A. Gursahanev, Michel Aubier, F. Lemaire, L. Tsaldari, L. Brochard, C. Gires, Ph. Dewailly, A. J. Schneider, F. Maltais, R. Traversa, J. Nicoiopoulos, F. Abroug, R. Schiener, J. H. Boix, Yu. Sirenko, D. Dell’Utri, C. Truchero, M. Narváez, Cl. Chastang, A. Peloux, D. Pavlovic, T. Lherm, B. Guidet, A. B. J. Groeneveld, V. Lópes, J. M. Gabillet, V. Cayrel, B. Huet, B. Renaud, A. Fernández, D. Perrin-Gachadoat, A. Herrejón, A. Tenaillon, H. Medaoui, Y. Furet, A. M. Durocher, I. Gültuna, L. Firestone, J. Marin, R. Calvo, H. Romo, M. Sovili, S. Bahrami, J. F. Vaxelaire, H Wiedeck, Apostolos Armaganidis, D. Perrin, J. A. Romand, M. Dambrosio, D. Olivares, B. Lafon, B. Rousset, G. Boussignac, M. Dojat, R. I. C. Wesdorp, V. Parra, N. Gueteau, D. Perrotin, W. Erdmann, Paolo Navalesi, J. Kesecioĝlu, M. Högman, S. Elatrous, G. Diaz-Regañón, J. C. Raphael, O. Leroy, P. Amstutz, F. Brunet, L. G. Thijs, H. Arnberg, F. Pochard, H. Georges, F. Boileau, F. Konrad, H. A. Bruining, J. L. Maravall, T. Vassal, Jean-Paul Mira, C. Mayaud, L. Babiy, J. C. Pompe, C. Ince, J. J. Lanore, P. Marino, G. Hedenstierna, H. Redl, J. Muñoz, A. Diaz-Prieto, Y. Yu, A. Cogliati, P. F. Dequin, F. J. Santos, M. Shchupak, S. Chevret, Ch Martínez, J. Moya, F. Saulnier, H. Hedenström, J. Blanquer, C. Lemaire, I. Hamy, G. Offenstadt, D. Pinquier, R. Boiteau, M. Kountouri, J. F. Dhainaut, F. Salord, C. Brun-Buisson, T. Boulain, J. Castañeda, A. Legras, J. Kilian, M. Jaafoura, and L. Gruez more...
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Acute/chronic respiratory failure ,medicine.medical_specialty ,Continuous Positive Airway Pressure ,Severe Acute Pancreatitis ,business.industry ,Pain medicine ,Critical Care and Intensive Care Medicine ,Pressure Support Ventilation ,Anesthesiology ,Poster Presentation ,Emergency medicine ,Medicine ,business ,Peak Inspiratory Pressure ,Acute Respiratory Failure - Published
- 1992
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44. Validity of the Upper Inflection Point in Acute Respiratory Distress Syndrome
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SERVILLO, GIUSEPPE, DE ROBERTIS, EDOARDO, TUFANO, ROSALBA, F. Rossano, L. Brochard, F. Lemaire, Servillo, Giuseppe, DE ROBERTIS, Edoardo, F., Rossano, L., Brochard, F., Lemaire, and Tufano, Rosalba
- Published
- 1999
45. Measurement of the upper inflection point on the pressure volume curve in ARDS patients
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SERVILLO, GIUSEPPE, DE ROBERTIS, EDOARDO, TUFANO, ROSALBA, V. Cotticelli, G. Facciolli, L. Brochard, F. Lemaire, Servillo, Giuseppe, V., Cotticelli, G., Facciolli, DE ROBERTIS, Edoardo, Tufano, Rosalba, L., Brochard, and F., Lemaire more...
- Published
- 1999
46. Recent Progress in Physics-Based Models of the Plasmasphere
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Viviane Pierrard, Jerry Goldstein, Nicolas André, Vania K. Jordanova, Galina A. Kotova, Joseph F. Lemaire, Mike W. Liemohn, and Hiroshi Matsui
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- 2009
- Full Text
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47. Effects of sodium-nitroprusside and urapidil on gas exchange and ventilation-perfusion relationships in patients with congestive heart failure
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S Adnot, P Radermacher, P Andrivet, JL Dubois-Rande, A Dupeyrat, and F Lemaire
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Pulmonary and Respiratory Medicine - Abstract
Vasodilators usually decrease arterial PO2 in patients with congestive heart failure (CHF) because of alteration in ventilation-perfusion (Va/Q) relationships. The effects of sodium nitroprusside (SNP) and urapidil (U), a new selective alpha 1-receptor antagonist, were investigated in seven patients with CHF. The distribution of ventilation and perfusion was examined using the multiple gas elimination technique. The haemodynamic responses to SNP and U were similar, cardiac index increasing by 25% with SNP and by 31% with U. Despite a similar increase of mixed venous oxygen tension, the arterial PO2 decreased from 11.3 +/- 0.8 to 9.6 +/- 0.6 kPa (p less than 0.01) with SNP but remained unchanged (11.0 +/- 0.9 vs 11.4 +/- 0.8 kPa, NS) with U. SNP and U both increased perfusion to lung units with Va/Q ratios of 0.1 or less with no change in shunt fraction. The fractional perfusion to total low Va/Q ratios (low Va/Q + shunt) was higher with SNP than with U (14.1 +/- 2.6 vs 9.5 +/- 2.3%, p less than 0.01). The results suggest that gas exchange and Va/Q relationships are altered less with U than with SNP in patients with CHF. more...
- Published
- 1991
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48. Chronic obstructive lung disease and intensive care
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F. Lemaire
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medicine.medical_specialty ,Anesthesiology and Pain Medicine ,business.industry ,Intensive care ,medicine ,Intensive care medicine ,medicine.disease ,business ,Obstructive lung disease - Published
- 1990
- Full Text
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49. Splicing precedes polyadenylation during Drosophila E74A transcription
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M F LeMaire and C S Thummel
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Cell Biology ,Molecular Biology - Abstract
The E74 gene is one of a small set of early genes induced by the steroid hormone ecdysone at the onset of metamorphosis in the fruit fly, Drosophila melanogaster. This complex gene directs the synthesis of a 60-kilobase (kb) primary transcript that is spliced to form the 6-kb E74A mRNA. In a previous study, we found that ecdysone directly activates the E74A promoter and determined that RNA polymerase II transcribes this gene at a rate of approximately 1.1 kb/min. This elongation rate accounts for most of the 1-hour delay seen between the addition of ecdysone and the appearance of cytoplasmic E74A mRNA (C. S. Thummel, K. C. Burtis, and D. S. Hogness, Cell 61:101-111, 1990). We show here that nascent E74A transcripts are spliced, and we propose a model for the order of that splicing. This study provides, for the first time, direct biochemical evidence for splicing of a low-abundance cellular RNA before transcription termination and polyadenylation. more...
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- 1990
- Full Text
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50. CMS physics technical design report, volume II: Physics performance
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Bayatian, G.L. Chatrchyan, S. Hmayakyan, G. Sirunyan, A.M. Adam, W. Bergauer, T. Dragicevic, M. Erö, J. Friedl, M. Fruehwirth, R. Ghete, V. Glaser, P. Hrubec, J. Jeitler, M. Krammer, M. Magrans, I. Mikulec, I. Mitaroff, W. Noebauer, T. Pernicka, M. Porth, P. Rohringer, H. Strauss, J. Taurok, A. Waltenberger, W. Walzel, G. Widl, E. Wulz, C.-E. Fedorov, A. Korzhik, M. Missevitch, O. Zuyeuski, R. Chekhovsky, V. Dvornikov, O. Emeliantchik, I. Litomin, A. Mossolov, V. Shumeiko, N. Solin, A. Stefanovitch, R. Suarez Gonzalez, J. Tikhonov, A. Petrov, V. D'Hondt, J. De Weirdt, S. Goorens, R. Heyninck, J. Lowette, S. Tavernier, S. Van Doninck, W. Van Lancker, L. Bouhali, O. Clerbaux, B. De Lentdecker, G. Dewulf, J.P. Mahmoud, T. Marage, P.E. Neukermans, L. Sundararajan, V. Vander Velde, C. Vanlaer, P. Wickens, J. Assouak, S. Bonnet, J.L. Bruno, G. Caudron, J. De Callatay, B. De Favereau De Jeneret, J. De Visscher, S. Delaere, C. Demin, P. Favart, D. Feltrin, E. Forton, E. Grégoire, G. Kalinin, S. Kcira, D. Keutgen, T. Leibenguth, G. Lemaitre, V. Liu, Y. Michotte, D. Militaru, O. Ninane, A. Ovyn, S. Pierzchala, T. Piotrzkowski, K. Roberfroid, V. Rouby, X. Teyssier, D. Van Der Aa, O. Vander Donckt, M. Daubie, E. Herquet, P. Mollet, A. Romeyer, A. Beaumont, W. Cardaci, M. De Langhe, E. De Wolf, E.A. Rurua, L. Souza, M.H.G. Oguri, V. Santoro, A. Sznajder, A. Vaz, M. Gregores, E.M. Novaes, S.F. Anguelov, T. Antchev, G. Atanasov, I. Damgov, J. Darmenov, N. Dimitrov, L. Genchev, V. Iaydjiev, P. Panev, B. Piperov, S. Stoykova, S. Sultanov, G. Vankov, I. Dimitrov, A. Kozhuharov, V. Litov, L. Makariev, M. Marinov, A. Marinova, E. Markov, S. Mateev, M. Pavlov, B. Petkov, P. Sabev, C. Stoynev, S. Toteva, Z. Verguilov, V. Chen, G.M. Chen, H.S. He, K.L. Jiang, C.H. Li, W.G. Liu, H.M. Meng, X. Shen, X.Y. Sun, H.S. Yang, M. Zhao, W.R. Zhuang, H.L. Ban, Y. Cai, J. Liu, S. Qian, S.J. Yang, Z.C. Ye, Y.L. Ying, J. Wu, J. Zhang, Z.P. Godinovic, N. Puljak, I. Soric, I. Antunovic, Z. Dzelalija, M. Marasovic, K. Brigljevic, V. Ferencek, D. Kadija, K. Morovic, S. Planinic, M. Nicolaou, C. Papadakis, A. Razis, P.A. Tsiakkouri, D. Hektor, A. Kadastik, M. Kannike, K. Lippmaa, E. Müntel, M. Raidal, M. Aarnio, P.A. Czellar, S. Haeggstroem, E. Heikkinen, A. Härkönen, J. Karimäki, V. Kinnunen, R. Lampén, T. Lassila-Perini, K. Lehti, S. Lindén, T. Luukka, P.R. Michal, S. Mäenpää, T. Nysten, J. Stettler, M. Tuominen, E. Tuominiemi, J. Wendland, L. Tuuva, T. Guillaud, J.P. Nedelec, P. Sillou, D. Anfreville, M. Beauceron, S. Bougamont, E. Bredy, P. Chipaux, R. Dejardin, M. Denegri, D. Descamps, J. Fabbro, B. Faure, J.L. Ganjour, S. Gentit, F.X. Givernaud, A. Gras, P. Hamel De Monchenault, G. Jarry, P. Kircher, F. Lemaire, M.C. Levesy, B. Locci, E. Lottin I Mandjavidze, J.P. Mur, M. Pasquetto, E. Payn, A. Rander, J. Reymond, J.M. Rondeaux, F. Rosowsky, A. Sun, Z.H. Verrecchia, P. Baffioni, S. Beaudette, F. Bercher, M. Berthon, U. Bimbot, S. Bourotte, J. Busson, P. Cerutti, M. Chamont, D. Charlot, C. Collard, C. Decotigny, D. Delmeire, E. Dobrzynski, L. Gaillac, A.M. Geerebaert, Y. Gilly, J. Haguenauer, M. Karar, A. Mathieu, A. Milleret, G. Miné, P. Paganini, P. Romanteau, T. Semeniouk, I. Sirois, Y. Berst, J.D. Brom, J.M. Didierjean, F. Drouhin, F. Fontaine, J.C. Goerlach, U. Graehling, P. Gross, L. Houchu, L. Juillot, P. Lounis, A. Maazouzi, C. Mangeol, D. Olivetto, C. Todorov, T. Van Hove, P. Vintache, D. Ageron, M. Agram, J.L. Baulieu, G. Bedjidian, M. Blaha, J. Bonnevaux, A. Boudoul, G. Chabanat, E. Combaret, C. Contardo, D. Della Negra, R. Depasse, P. Dupasquier, T. El Mamouni, H. Estre, N. Fay, J. Gascon, S. Giraud, N. Girerd, C. Haroutunian, R. Ianigro, J.C. Ille, B. Lethuillier, M. Lumb, N. Mathez, H. Maurelli, G. Mirabito, L. Perries, S. Ravat, O. Kvatadze, R. Roinishvili, V. Adolphi, R. Brauer, R. Braunschweig, W. Esser, H. Feld, L. Heister, A. Karpinski, W. Klein, K. Kukulies, C. Olzem, J. Ostapchuk, A. Pandoulas, D. Pierschel, G. Raupach, F. Schael, S. Schwering, G. Thomas, M. Weber, M. Wittmer, B. Wlochal, M. Adolf, A. Biallass, P. Bontenackels, M. Erdmann, M. Fesefeldt, H. Hebbeker, T. Hermann, S. Hilgers, G. Hoepfner, K. Hof, C. Kappler, S. Kirsch, M. Lanske, D. Philipps, B. Reithler, H. Rommerskirchen, T. Sowa, M. Szczesny, H. Tonutti, M. Tsigenov, O. Beissel, F. Davids, M. Duda, M. Flügge, G. Franke, T. Giffels, M. Hermanns, T. Heydhausen, D. Kasselmann, S. Kaussen, G. Kress, T. Linn, A. Nowack, A. Poettgens, M. Pooth, O. Stahl, A. Tornier, D. Weber, M. Flossdorf, A. Hegner, B. Mnich, J. Rosemann, C. Flucke, G. Holm, U. Klanner, R. Pein, U. Schirm, N. Schleper, P. Steinbrück, G. Stoye, M. Van Staa, R. Wick, K. Blüm, P. Buege, V. De Boer, W. Dirkes, G. Fahrer, M. Feindt, M. Felzmann, U. Fernandez Menendez, J. Frey, M. Furgeri, A. Hartmann, F. Heier, S. Jung, C. Ledermann, B. Müller, Th. Niegel, M. Oehler, A. Ortega Gomez, T. Piasecki, C. Quast, G. Rabbertz, K. Saout, C. Scheurer, A. Schieferdecker, D. Schmidt, A. Simonis, H.J. Theel, A. Vest, A. Weiler, T. Weiser, C. Weng, J. Zhukov, V. Karapostoli, G. Katsas, P. Kreuzer, P. Panagiotou, A. Papadimitropoulos, C. Anagnostou, G. Barone, M. Geralis, T. Kalfas, C. Koimas, A. Kyriakis, A. Kyriazopoulou, S. Loukas, D. Markou, A. Markou, C. Mavrommatis, C. Theofilatos, K. Vermisoglou, G. Zachariadou, A. Aslanoglou, X. Evangelou, I. Kokkas, P. Manthos, N. Papadopoulos, I. Sidiropoulos, G. Triantis, F.A. Bencze, G. Boldizsar, L. Hajdu, C. Horvath, D. Laszlo, A. Odor, G. Sikler, F. Toth, N. Vesztergombi, G. Zalan, P. Molnar, J. Beni, N. Kapusi, A. Marian, G. Raics, P. Szabo, Z. Szillasi, Z. Zilizi, G. Bawa, H.S. Beri, S.B. Bhandari, V. Bhatnagar, V. Kaur, M. Kaur, R. Kohli, J.M. Kumar, A. Singh, J.B. Bhardwaj, A. Bhattacharya, S. Chatterji, S. Chauhan, S. Choudhary, B.C. Gupta, P. Jha, M. Ranjan, K. Shivpuri, R.K. Srivastava, A.K. Borkar, S. Dixit, M. Ghodgaonkar, M. Kataria, S.K. Lalwani, S.K. Mishra, V. Mohanty, A.K. Topkar, A. Aziz, T. Banerjee, S. Bose, S. Cheere, N. Chendvankar, S. Deshpande, P.V. Guchait, M. Gurtu, A. Maity, M. Majumder, G. Mazumdar, K. Nayak, A. Patil, M.R. Sharma, S. Sudhakar, K. Tonwar, S.C. Acharya, B.S. Banerjee, S. Bheesette, S. Dugad, S. Kalmani, S.D. Lakkireddi, V.R. Mondal, N.K. Panyam, N. Verma, P. Arabgol, M. Arfaei, H. Hashemi, M. Mohammadi, M. Mohammadi Najafabadi, M. Moshaii, A. Paktinat Mehdiabadi, S. Grunewald, M. Abbrescia, M. Barbone, L. Colaleo, A. Creanza, D. De Filippis, N. De Palma, M. Donvito, G. Fiore, L. Giordano, D. Iaselli, G. Loddo, F. Maggi, G. Maggi, M. Manna, N. Marangelli, B. Mennea, M.S. My, S. Natali, S. Nuzzo, S. Pugliese, G. Radicci, V. Ranieri, A. Romano, F. Selvaggi, G. Silvestris, L. Tempesta, P. Trentadue, R. Zito, G. Abbiendi, G. Bacchi, W. Benvenuti, A. Bonacorsi, D. Braibant-Giacomelli, S. Capiluppi, P. Cavallo, F.R. Ciocca, C. Codispoti, G. D'Antone, I. Dallavalle, G.M. Fabbri, F. Fanfani, A. Giacomelli, P. Grandi, C. Guerzoni, M. Guiducci, L. Marcellini, S. Masetti, G. Montanari, A. Navarria, F. Odorici, F. Perrotta, A. Rossi, A. Rovelli, T. Siroli, G. Travaglini, R. Albergo, S. Chiorboli, M. Costa, S. Galanti, M. Gatto Rotondo, G. Noto, F. Potenza, R. Russo, G. Tricomi, A. Tuve, C. Bocci, A. Ciraolo, G. Ciulli, V. Civinini, C. D'Alessandro, R. Focardi, E. Genta, C. Lenzi, P. Macchiolo, A. Magini, N. Manolescu, F. Marchettini, C. Masetti, L. Mersi, S. Meschini, M. Paoletti, S. Parrini, G. Ranieri, R. Sani, M. Fabbricatore, P. Farinon, S. Greco, M. Cattaneo, G. De Min, A. Dominoni, M. Farina, F.M. Ferri, F. Ghezzi, A. Govoni, P. Leporini, R. Magni, S. Malberti, M. Malvezzi, S. Marelli, S. Menasce, D. Moroni, L. Negri, P. Paganoni, M. Pedrini, D. Pullia, A. Ragazzi, S. Redaelli, N. Rovelli, C. Rovere, M. Sala, L. Sala, S. Salerno, R. Tabarelli De Fatis, T. Vigano', S. Comunale, G. Fabozzi, F. Lomidze, D. Mele, S. Paolucci, P. Piccolo, D. Polese, G. Sciacca, C. Azzi, P. Bacchetta, N. Bellato, M. Benettoni, M. Bisello, D. Borsato, E. Candelori, A. Checchia, P. Conti, E. De Mattia, M. Dorigo, T. Drollinger, V. Fanzago, F. Gasparini, F. Gasparini, U. Giarin, M. Giubilato, P. Gonella, F. Kaminskiy, A. Karaevskii, S. Khomenkov, V. Lacaprara, S. Lippi, I. Loreti, M. Lytovchenko, O. Mazzucato, M. Meneguzzo, A.T. Michelotto, M. Montecassiano, F. Nigro, M. Passaseo, M. Pegoraro, M. Rampazzo, G. Ronchese, P. Torassa, E. Ventura, S. Zanetti, M. Zotto, P. Zumerle, G. Belli, G. Berzano, U. De Vecchi, C. Guida, R. Necchi, M.M. Ratti, S.P. Riccardi, C. Sani, G. Torre, P. Vitulo, P. Ambroglini, F. Babucci, E. Benedetti, D. Biasini, M. Bilei, G.M. Caponeri, B. Checcucci, B. Fanò, L. Lariccia, P. Mantovani, G. Passeri, D. Pioppi, M. Placidi, P. Postolache, V. Ricci, D. Santocchia, A. Servoli, L. Spiga, D. Azzurri, P. Bagliesi, G. Basti, A. Benucci, L. Bernardini, J. Boccali, T. Borrello, L. Bosi, F. Calzolari, F. Castaldi, R. Cerri, C. Cucoanes, A.S. D'Alfonso, M. Dell'Orso, R. Dutta, S. Foà, L. Gennai, S. Giammanco, A. Giassi, A. Kartashov, D. Ligabue, F. Linari, S. Lomtadze, T. Lungu, G.A. Mangano, B. Martinelli, G. Massa, M. Messineo, A. Moggi, A. Palla, F. Palmonari, F. Petrucciani, G. Raffaelli, F. Rizzi, A. Sanguinetti, G. Segneri, G. Sentenac, D. Serban, A.T. Sguazzoni, G. Slav, A. Spagnolo, P. Tenchini, R. Tonelli, G. Venturi, A. Verdini, P.G. Vos, M. Baccaro, S. Barone, L. Bartoloni, A. Cavallari, F. Costantini, S. Dafinei, I. Del Re, D. Diemoz, M. Gargiulo, C. Longo, E. Meridiani, P. Organtini, G. Rahatlou, S. Accomando, E. Arneodo, M. Ballestrero, A. Bellan, R. Biino, C. Bolognesi, S. Cartiglia, N. Cerminara, G. Cordero, M. Costa, M. Dellacasa, G. Demaria, N. Maina, E. Mariotti, C. Maselli, S. Mereu, P. Migliore, E. Monaco, V. Nervo, M. Obertino, M.M. Pastrone, N. Petrillo, G. Romero, A. Ruspa, M. Sacchi, R. Staiano, A. Trapani, P.P. Belforte, S. Cossutti, F. Della Ricca, G. Penzo, A. Cho, K. Ham, S.W. Han, D. Kim, D.H. Kim, G.N. Kim, J.C. Kim, W.Y. Lee, M.W. Oh, S.K. Park, W.H. Ro, S.R. Son, D.C. Suh, J.S. Kim, J.Y. Jung, S.Y. Rhee, J.T. Hong, B.S. Hong, S.J. Lee, K.S. Park, I. Park, S.K. Sim, K.S. Won, E. Kim, S.B. Carrillo Moreno, S. Castilla Valdez, H. Sanchez Hernandez, H.A. Salazar Ibarguen, H.A. Morelos Pineda, A. Gray, R.N.C. Krofcheck, D. Bernardino Rodrigues, N. Butler, P.H. Williams, J.C. Aftab, Z. Ahmad, M. Ahmad, U. Ahmed, I. Alam Jan, J. Asghar, M.I. Asghar, S. Hafeez, M. Hoorani, H.R. Ibrahim, M. Iftikhar, M. Khan, M.S. Qaiser, N. Rehman, I. Solaija, T. Toor, S. Blocki, J. Cyz, A. Gladysz-Dziadus, E. Mikocki, S. Turnau, J. Wlodarczyk, Z. Zychowski, P. Bunkowski, K. Czyrkowski, H. Dabrowski, R. Dominik, W. Doroba, K. Kalinowski, A. Konecki, M. Krolikowski, J. Kudla, I.M. Pietrusinski, M. Pozniak, K. Zabolotny, W. Zych, P. Bluj, M. Gokieli, R. Goscilo, L. Górski, M. Nawrocki, K. Traczyk, P. Wrochna, G. Zalewski, P. Alemany-Fernandez, R. Almeida, C. Almeida, N. Araujo Trindade, A. Bordalo, P. Da Silva Rodrigues, P. Husejko, M. Jain, A. Kazana, M. Musella, P. Ramos, S. Rasteiro Da Silva, J. Ribeiro, P.Q. Santos, M. Semiao, J. Silva, P. Teixeira, I. Teixeira, J.P. Varela, J. Afanasiev, S. Babich, K. Belotelov, I. Elsha, V. Ershov, Y. Filozova, I. Golunov, A. Golutvin, I. Gorbounov, N. Gramenitski, I. Kalagin, V. Kamenev, A. Karjavin, V. Khabarov, S. Khabarov, V. Kiryushin, Y. Konoplyanikov, V. Korenkov, V. Kozlov, G. Kurenkov, A. Lanev, A. Lysiakov, V. Malakhov, A. Melnitchenko, I. Mitsyn, V.V. Moisenz, K. Moisenz, P. Movchan, S. Nikonov, E. Oleynik, D. Palichik, V. Perelygin, V. Petrosyan, A. Rogalev, E. Samsonov, V. Savina, M. Semenov, R. Shmatov, S. Shulha, S. Smirnov, V. Smolin, D. Tcheremoukhine, A. Teryaev, O. Tikhonenko, E. Vassiliev, S. Vishnevskiy, A. Volodko, A. Zamiatin, N. Zarubin, A. Zarubin, P. Zubarev, E. Bondar, N. Golovtsov, V. Golyash, A. Ivanov, Y. Kim, V. Kozlov, V. Lebedev, V. Makarenkov, G. Orishchin, E. Shevel, A. Sknar, V. Smirnov, I. Sulimov, V. Tarakanov, V. Uvarov, L. Velichko, G. Volkov, S. Vorobyev, A. 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Korjenevski, S. Sakumoto, W. Slattery, P. Tipton, P. Zielinski, M. Bartz, E. Doroshenko, J. Halkiadakis, E. Jacques, P.F. Kalelkar, M.S. Khits, D. Lath, A. Macpherson, A. Perera, L. Plano, R. Rose, K. Schnetzer, S. Somalwar, S. Stone, R. Thomson, G. Watts, T.L. Akchurin, N. Carrell, K.W. Gumus, K. Jeong, C. Kim, H. Papadimitriou, V. Sill, A. Spezziga, M. Washington, E. Wigmans, R. Zhang, L. Bapty, T. Engh, D. Johns, W. Keskinpala, T. Luiggi Lopez, E. Neema, S. Nordstrom, S. Pathak, S. Sheldon, P. Vaandering, E.W. Webster, M. Arenton, M.W. Conetti, S. Cox, B. Hirosky, R. Imlay, R. Ledovskoy, A. Phillips Ii, D. Powell, H. Ronquest, M. Smith, D. Baek, Y.W. Bellinger, J.N. Bradley, D. Carlsmith, D. Crotty, I. Dasu, S. Feyzi, F. Gorski, T. Grothe, M. Hogg, W. Jaworski, M. Klabbers, P. Lanaro, A. Loveless, R. De Magrans Abril, M. Reeder, D. Smith, W.H. Wenman, D. Atoyan, G.S. Dhawan, S. Issakov, V. Neal, H. Poblaguev, A. Zeller, M.E. Yuldashev, B.S. more...
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High Energy Physics::Phenomenology ,High Energy Physics::Experiment - Abstract
CMS is a general purpose experiment, designed to study the physics of pp collisions at 14 TeV at the Large Hadron Collider (LHC). It currently involves more than 2000 physicists from more than 150 institutes and 37 countries. The LHC will provide extraordinary opportunities for particle physics based on its unprecedented collision energy and luminosity when it begins operation in 2007. The principal aim of this report is to present the strategy of CMS to explore the rich physics programme offered by the LHC. This volume demonstrates the physics capability of the CMS experiment. The prime goals of CMS are to explore physics at the TeV scale and to study the mechanism of electroweak symmetry breaking - through the discovery of the Higgs particle or otherwise. To carry out this task, CMS must be prepared to search for new particles, such as the Higgs boson or supersymmetric partners of the Standard Model particles, from the start-up of the LHC since new physics at the TeV scale may manifest itself with modest data samples of the order of a few fb-1 or less. The analysis tools that have been developed are applied to study in great detail and with all the methodology of performing an analysis on CMS data specific benchmark processes upon which to gauge the performance of CMS. These processes cover several Higgs boson decay channels, the production and decay of new particles such as Z′ and supersymmetric particles, Bs production and processes in heavy ion collisions. The simulation of these benchmark processes includes subtle effects such as possible detector miscalibration and misalignment. Besides these benchmark processes, the physics reach of CMS is studied for a large number of signatures arising in the Standard Model and also in theories beyond the Standard Model for integrated luminosities ranging from 1 fb-1 to 30 fb-1. The Standard Model processes include QCD, B-physics, diffraction, detailed studies of the top quark properties, and electroweak physics topics such as the W and Z0 boson properties. The production and decay of the Higgs particle is studied for many observable decays, and the precision with which the Higgs boson properties can be derived is determined. About ten different supersymmetry benchmark points are analysed using full simulation. The CMS discovery reach is evaluated in the SUSY parameter space covering a large variety of decay signatures. Furthermore, the discovery reach for a plethora of alternative models for new physics is explored, notably extra dimensions, new vector boson high mass states, little Higgs models, technicolour and others. Methods to discriminate between models have been investigated. This report is organized as follows. Chapter 1, the Introduction, describes the context of this document. Chapters 2-6 describe examples of full analyses, with photons, electrons, muons, jets, missing E T, B-mesons and τ's, and for quarkonia in heavy ion collisions. Chapters 7-15 describe the physics reach for Standard Model processes, Higgs discovery and searches for new physics beyond the Standard Model. © 2007 IOP Publishing Ltd. more...
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- 2007
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