1. PATTERN OF PRESENTATION AND MICROBIAL ISOLATES OF CORNEAL ULCERS AT ALEX EKWUEME FEDERAL UNIVERSITY TEACHING HOSPITAL ABAKALIKI.
- Author
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Ogbonnaya, C. E., Ezeanosike, E., Ekpe, V. U., Ojide, C. K., Ezisi, C. N., Joe-Akunne, K. K., and Ginger-Eke, H. A.
- Subjects
CORNEAL ulcer ,ACADEMIC medical centers ,RESEARCH methodology ,SEVERITY of illness index ,OCULAR injuries ,SELF medication ,TREATMENT effectiveness ,EYE infections ,STAPHYLOCOCCUS aureus ,CORNEAL transplantation ,VISUAL acuity ,BACTERIAL diseases ,DATA analysis software ,PSEUDOMONAS ,VISION disorders ,DISEASE management ,LONGITUDINAL method ,EVALUATION - Abstract
Background: Corneal ulceration is sight-threatening. Accurate determination of the pattern, causative organisms and factors affecting severity and outcome will guide management. Objectives: To determine the pattern and microbiological diagnosis of corneal ulcers seen at Alex Ekwueme Federal University Teaching Hospital Abakaliki (AEFUTHA). Materials and Methods: This was a longitudinal descriptive study of all consenting consecutive corneal ulcer patients managed at AEFUTHA from December 2018 to December 2019. Socio-demographic data, relevant history, clinical and laboratory findings were documented. Data was analysed using Statistical Package for Social Sciences (SPSS) version 22. Findings: There were 18 corneal ulcer patients among the 3853 consecutive new patients seen within the study period (a hospital prevalence rate of 0.47%). All 18 patients were recruited. They were aged 23 to 84 years; mean age was 50.4 ± 15.7. Majority were females 11(61.1%); 50% were farmers; 50% had preceding eye injury; 94% practiced prior self-medication; 72.2% presented ≥ 2 weeks after onset of symptoms. The ulcers were mostly central (61.1%); wide (>5 mm) 77.8% and deep (posterior stromal) 77.8%. Microorganisms isolated from 11(61.1%) specimens were: bacteria 6 (54.5%); fungi 4 (36.4%); acanthamoeba 1 (9.1%). Bacterial isolates were: staphylococcus aureus (5.6%) and pseudomonas aeruginosa (5.6%). Conclusion: Corneal ulcers presenting at AEFUTHA were severe (centrallylocated, wide and deep) with poor visual outcome after treatment. The microbial isolates were bacteria, fungi and acanthamoeba. Late presentation after prior self-medication was common. Public education on early hospital presentation is necessary. Corneal transplant services are also needed for visual rehabilitation. [ABSTRACT FROM AUTHOR]
- Published
- 2023