95 results on '"Eze, U"'
Search Results
2. Effects of Controlled Generator Fume Emissions on the Levels of Troponin I, C-Reactive Protein and Oxidative Stress Markers in Dogs: Exploring Air Pollution-Induced Cardiovascular Disease in a Low-Resource Country
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Eze, U. U., Eke, I. G., Anakwue, R. C., Oguejiofor, C. F., Onyejekwe, O. B., Udeani, I. J., Onunze, C. J., Obed, U. J., Eze, A. A., Anaga, A. O., and Anene, B. M.
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- 2021
- Full Text
- View/download PDF
3. Development of a Blockchain System for Licensing Services for Nigerian Communications Commission
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Iwuala, Chibueze, primary, Eze, U. F., additional, Chukwudebe, G., additional, and Etus, C., additional
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- 2024
- Full Text
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4. Perception of Substance Use Disorder Training: a Survey of General Psychiatry Residents in Nigeria
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Chikezie, Eze U., Ebuenyi, Ikenna D., Allagoa, Erefagha Leonardo P., and Onyeka, Ifeoma N.
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- 2021
- Full Text
- View/download PDF
5. Assessment of the knowledge of healthcare workers on monkeypox in Nigeria
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Eze, U, Okafor, N, Ozota, G, Nworie, K, Asogwa, C, Richard, I, Ilochonwu, AP, Ezeasor, S, Okorie, C, Ben-Umeh, K, Ezeh, A, Aboh, M, Isah, A, Eze, U, Okafor, N, Ozota, G, Nworie, K, Asogwa, C, Richard, I, Ilochonwu, AP, Ezeasor, S, Okorie, C, Ben-Umeh, K, Ezeh, A, Aboh, M, and Isah, A
- Abstract
Background: Monkeypox, a re-emerging zoonotic disease caused by the monkeypox virus (MPXV), poses a public health challenge in Nigeria. To effectively combat this disease, it is essential to assess the knowledge of healthcare workers (HCWs) in Nigeria concerning monkeypox outbreak.Methods: A cross-sectional web-based survey with 609 healthcare workers in Nigeria was conducted using a structured questionnaire to assess their knowledge of monkeypox. Data were coded and analyzed with Microsoft Excel and Python in Anaconda Jupyter Notebook.Results: The majority of respondents (n=318, 52.2%) had good knowledge of MPXV but also had knowledge gaps regarding certain symptoms and disease similarities. Interestingly, respondents were completely unaware of the possibility of sexual transmission of the disease. However, they recognized the possible significant impact of monkeypox on the social and economic lifestyle of Nigerians (n=582, 95.6%, adjOR=21.181, 95% CI: 14.450-31.051). Respondents had mixed knowledge regarding the use of smallpox vaccines and antiviral agents for monkeypox prevention and treatment. Furthermore, a significant proportion (n=526, 86.4%, adjOR=0.159, 95% CI: 0.126-0.201) attributed the outbreak to bioterrorism. The logistic regression highlighted a strong influence of academic qualification, type of healthcare provider, years of experience, and geopolitical zone of practice, on monkeypox knowledge in Nigeria.Conclusion: The study highlights the importance of continuous education for healthcare professionals in Nigeria to improve monkeypox outbreak management. Despite their moderate performance, there are knowledge gaps in critical areas among HCWs, necessitating further research to explore reasons and influencing factors for knowledge levels., Hintergrund: Affenpocken, eine wiederaufgetretende Zoonose, die durch das Affenpockenvirus (MPXV) verursacht wird, stellt eine Herausforderung für die öffentliche Gesundheit in Nigeria dar. Um diese Krankheit wirksam zu bekämpfen, ist es wichtig, das Wissen der Beschäftigten im Gesundheitswesen in Nigeria über den Ausbruch der Affenpocken zu bewerten.Methode: Anhand eines strukturierten Fragebogens wurde eine webbasierte Querschnittserhebung bei 609 Beschäftigten des Gesundheitswesens in Nigeria durchgeführt, um ihr Wissen über Affenpocken zu ermitteln. Die Daten wurden mit Microsoft Excel und Python in Anaconda Jupyter Notebook kodiert und analysiert.Ergebnisse: Die Mehrheit der Befragten (n=318, 52,2%) verfügte über gute Kenntnisse über MPXV, hatte aber Wissenslücken in Bezug auf bestimmte Symptome und Ähnlichkeiten mit anderen Krankheiten. Interessanterweise waren sich die Befragten der Möglichkeit einer sexuellen Übertragung der Krankheit überhaupt nicht bewusst. Sie erkannten jedoch die möglichen erheblichen Auswirkungen der Affenpocken auf die soziale und wirtschaftliche Lebensweise der Nigerianer (n=582, 95,6%, adjOR=21.181, 95% CI: 14.450-31.051). Die Befragten hatten unterschiedliche Kenntnisse über die Verwendung von Pockenimpfstoffen und antiviralen Mitteln zur Vorbeugung und Behandlung von Affenpocken. Außerdem führte ein signifikanter Anteil (n=526, 86,4%, adjOR=0.159, 95% CI: 0.126-0.201) den Ausbruch auf Bioterrorismus zurück. Die logistische Regression zeigte einen starken Einfluss der akademischen Qualifikation, der Art des Gesundheitsdienstleisters, der Jahre an Erfahrung und der geopolitischen Zone, in der man praktiziert, auf das Wissen über Windpocken in Nigeria.Schlussfolgerung: Die Studie unterstreicht, wie wichtig eine kontinuierliche Fortbildung des Gesundheitspersonals in Nigeria ist, um den Umgang mit dem Ausbruch der Affenpocken zu verbessern. Trotz ihrer mäßigen Fortschritte gibt es bei den Beschäftigten des Gesundheitswesens Wissenslück
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- 2024
6. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic : a comprehensive demographic analysis for the Global Burden of Disease Study 2021
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Schumacher, A. E., Kyu, H. H., Antony, C. M., Aravkin, A. Y., Azhar, G. S., Bisignano, C., Burkart, K., Cercy, K. M., Chung, E., Coberly, K., Comfort, H., Cousin, E., Culbreth, G. T., Cunningham, M., Weaver, N. D., Degenhardt, L., Deitesfeld, L., Dirac, M. A., Estep, K., Feigin, V. L., Flaxman, A. D., Flor, L. S., Force, L. M., Fuller, J. E., Gakidou, E., Hay, S. I., Ikuta, K. S., Jones, D. P., Kassebaum, N. J., Kassel, M. B., Keller, C., Kinzel, K. E., Krohn, K. J., Lozano, R., May, E. A., McKowen, A. W., McLaughlin, S. A., Mehlman, M. L., Mestrovic, T., Mokdad, A. H., Mosser, J. F., Mougin, V., Naghavi, M., Nesbit, O. D., Novotney, A., Ozten, Y., Pease, S. A., Pigott, D. M., Reiner, R. C., Robinson-Oden, H. E., Shaw, D. H., Slepak, E. L. N., Sorensen, R. J. D., Verghese, N. A., Vollset, S., Vongpradith, A., Vos, T., Wang, D., Watson, S., Weaver, M. R., Wells, K. M., Wilson, S., Wool, E. E., Zheng, P., Lim, S. S., Murray, C. J. L., Boyko, E. J., Chahine, Y., Kalani, R., Krishnamoorthy, V., Khalil, I. A., Minja, N. W., Morrison, S. D., Nafukho, F. M., Olivas-Martinez, A., Orellana, E., Tram, K., Aali, A., Rahnavard, N., Ahmadzade, A., Mohammad-Pour, S., Morovatdar, N., Pourali, G., Zafari, N., Abbafati, C., Cattaruzza, M. S., Abbas, J., Phillips, M. R., Abbasgholizadeh, R., Emamverdi, M., Friedman, J., Abbasi, M. A., Daneshvar, S., Dashti, M., Ghasemzadeh, A., Mirza-Aghazadeh-Attari, M., Doshmangir, L., Ghafourifard, M., Lotfi, M., Hosseini, M., Jadidi-Niaragh, F., Kalankesh, L. R., Karimi, S., Mohammad-Alizadeh-Charandabi, S., Khalafi, M., Mirghafourvand, M., Mirinezhad, S., Heris, R. M., Mousavi, S., Kafil, H. S., Abbasian, M., Momenzadeh, K., Santos, F. C. D., Carr, S., Chi, G., Elgendy, I. Y., Feroze, A. H., Kempen, J. H., Kubeisy, C. M., Li, Z., Rohloff, P., Liu, X., Natto, Z. S., Olanipekun, T. O., Pigeolet, M., Pradhan, P. M. S., Zweck, E., Sharfaei, S., Sheikh, A., Abtahi, D., Salimi, S., Shakeri, A., Tajbakhsh, A., Aghamiri, S., Ahmadzade, M., Hashemi, M. B., Ajami, M., Asgary, S., Ghasemi, M., Hassanian-Moghaddam, H., Kolahi, A., Nikoobar, A., Heidari-Foroozan, M., Montazeri, F., Nejadghaderi, S., Rahmani, S., Ziaeefar, P., Hesami, H., Zahir, M., Jahankhani, K., Rasouli-Saravani, A., Jahanmehr, N., Kashani, H. K., Nasiri, M., Raee, P., Rezaee, M., Safi, S., Shool, S., Tabatabai, S., ElHafeez, S. A., Tantawi, M. E., Elmeligy, O. A. A., Ghazy, R. M., Talaat, I. M., Abdelmasseh, M., Sanabria, J., Abd-Elsalam, S., Abdelwahab, A., Abdollahi, M., Abolhassani, H., Rezaei, N., Saghazadeh, A., Ala, M., Noroozi, N., Bahri, R. A., Khatami, F., Ayyoubzadeh, S., Azadnajafabad, S., Keykhaei, M., Momtazmanesh, S., Mousavi, P., Behnoush, A., Farrokhpour, H., Karimi, H., Khalaji, A., Khanmohammadi, S., Mayeli, M., Mohammadi, S., Eskandarieh, S., Sahraian, M., Fahimi, S., Malekzadeh, R., Mansouri, V., Sepanlou, S. G., Ghassemi, F., Haddadi, M., Kazemian, S., Khadembashiri, M., Khamesipour, F., Khavandegar, A., Khormali, M., Salamati, P., Kompani, F., Larijani, B., Mirdamadi, N., Seyedi, S., Malazy, O. T., Mahmoudi, E., Rashedi, S., Rad, E. M., Mansournia, M., Nasab, E. M., Mohammadshahi, M., Mostafavi, H., SeyedAlinaghi, S., Shafie, M., Shahbandi, A., Vahdani, A. M., Sharifan, A., Shirkoohi, R., Sohrabi, H., Tavangar, S., Heidari-Soureshjani, R., Abdoun, M., Abdullahi, A., Awotidebe, A. W., Borodo, S. B., Gadanya, M. A., Ladan, M., Ali, M. U., Tyrovolas, S., Abdurehman, A. M., Debele, A. T., Getachew, T., Gudeta, M. D., Misgana, T., Sertsu, A., Abebe, M., Ayele, G. M., Afework, A., Lerango, T. L., Tebeje, T. M., Sibhat, M. M., Tesfaye, S. H., Abedi, A., Gholamrezanezhad, A., Salehi, S., Athari, S., Hanifi, N., Abegaz, T. M., Kifle, Z. D., Zuñiga, R. A. A., Abhilash, E. S., Abiodun, O. O., Aboagye, R. G., Amu, H., Ayanore, M. A., Dowou, R. K., Immurana, M., Klu, D., Orish, V. N., Carrero, J. J., Cederroth, C. R., Deuba, K., Laflamme, L., Fereshtehnejad, S., Kauppila, J. H., Abouzid, M., Abreu, L. G., Malta, D. C., Prates, E. J. S., Nascimento, B. R., Abrha, W. A., Weldemariam, A. H., Girmay, A., Abrigo, M. R. M., Rumeileh, S. A., Abu-Rmeileh, N. M., Aburuz, S., Ahmed, L. A., Alam, Z., Elbarazi, I., Grivna, M., Nauman, J., Khan, G., Khan, M. A., Zaki, N., Ahmad, M. M., Abu-Zaid, A., Temsah, R. M. H., Zand, R., Acuna, J. M., Gautam, P., Chowdhury, R., Adair, T., Jiang, H., Babu, A. S., Borschmann, R., Meretoja, A., Wijeratne, T., Addo, I. Y., Okeke, S. R., Dai, Z., Xu, X., Huda, M., Mitchell, P. B., Peden, A. E., Resnikoff, S., Sharma, S., Si, Y., Sitas, F., Ye, P., Adebayo, O. M., Aladelusi, T. O., Salami, A. A., Ilesanmi, O. S., Owolabi, M. O., Adegboye, O. A., Adekanmbi, V., AlBataineh, M. T., Almahmeed, W., Aden, B., Adepoju, A. V., Adetunji, C. O., Adeyeoluwa, T. E., Oyeyemi, I. T., Oyeyemi, O. T., Udoakang, A. J., Adeyomoye, O. I., Anuoluwa, I. A., Bello, O. O., Oluwafemi, Y. D., Ekundayo, T. C., Idowu, O. O., Oluwatunase, G. O., Afolabi, A. A., Ekholuenetale, M., Fagbamigbe, A. F., Olufadewa, I. I., Ibitoye, S. E., Okekunle, A. P., Adha, R., Adikusuma, W., Adibi, A., Chen, M., Hossain, M., Rasali, D. P., Pashaei, A., Adnani, Q. E. S., Postma, M. J., Adra, S., Barqawi, H. J., Dash, N. R., Halwani, R., Maghazachi, A. A., Saber-Ayad, M. M., Sharif-Askari, N. S., Ahmad, F., Saddik, B., Saleh, M. A., Alzoubi, K. H., Omar, H. A., Arumugam, A., Bustanji, Y., Elemam, N. M., Faris, M. E. M., Karim, A., Qaisar, R., Semreen, M. H., Soliman, S. S. M., Altirkawi, K. A., Afraz, A., Ilaghi, M., Nematollahi, M., Afyouni, S., Amindarolzarbi, A., Zandieh, G. G. Z., Columbus, A., Kamireddy, A., Shafaat, O., Kazemi, F., Vervoort, D., Zhang, H., Jamshidi, E., Afzal, S., Agasthi, P., Agodi, A., Barchitta, M., D'Amico, E., Maugeri, A., Veroux, M., Biondi, A., Isola, G., Vacante, M., Falzone, L., Libra, M., Agyemang-Duah, W., Nikpoor, A., Ahinkorah, B. O., Demant, D., Ahmad, A., Mustafa, G., Pathan, A. R., Tabish, M., Ahmad, D., Bagheri, N., Burns, R. A., Cherbuin, N., Ahmad, T., Ahmadi, K., Saxena, S., Beaney, T., Palladino, R., Rawaf, S., Mossialos, E., Rawaf, D. L., Ahmed, A., Siddig, E. E., Ahmed, H., Ahmed, M. B., Shiferaw, D., Ashemo, M. Y., Gerema, U., Getachew, M. E., Bayileyegn, N. S., Mohamed, A. I., Eshetie, T. C., Tiruye, T. Y., Ahmed, S., Ali, H., Bodunrin, A. O., Tumurkhuu, M., Tung, K., Ubah, C. S., Aruleba, R. T., Aji, B., Ajumobi, O., Akalu, G. T., Beyene, H. B., Deribe, K., Ijo, D., Kassaw, N. A., Akara, E., Akinosoglou, K., Akkala, S., Asaad, M., Hassan, A. M., Bleyer, A., Akyirem, S., Bell, M. L., Song, Y., Etaee, F., Goldust, M., Li, W., Pawar, S., Hamad, H. A., Sathian, B., Hasan, S. A., Homsi, A. A., Almidani, O., Göbölös, L., Qadire, M. A., AL-Ahdal, T. M. A., Chen, S., Moazen, B., Alalalmeh, S. O., Hegazi, O. E., Shahwan, M. J., Shamsi, M. A., Zyoud, S. H., Al-Aly, Z., Wang, C., Alam, K., Alam, M., Al-Amer, R. M., Naik, G. R., Alanzi, T. M., Bah, S., Menezes, R. G., Alanezi, F. M., Albashtawy, M., Aldridge, R. W., Chung, S., Hossain, S., Kim, J., Kivimäki, M., Sunkersing, D., Umar, T., Zumla, A., Alemi, S., Al-Eyadhy, A., Temsah, M., Alhabib, K. F., ElGohary, G. M. T., Meo, S. A., Al-Gheethi, A. A. S., Kiross, G. T., Alhalaiqa, F. A. N., Al-Maweri, S. A. A., Alomari, M. A., Mohammed, M., Al-Hanawi, M. K., Binmadi, N., Malik, A. A., Samargandy, S., Ali, A., Khan, I., Sawyer, S. M., Ali, B. A., Ali, R., Ali, S. S., Ali, Z., Samakkhah, S. A., Alicandro, G., Alif, S. M., Maharjan, P., Rai, P., Hasan, M., Thapa, R., Thrift, A. G., Aligol, M., Alimi, R., Aliyi, A. A., Jema, A., Al-Jumaily, A., Hankey, G. J., Kujan, O., Mansour, A., Aljunid, S. M., Al-Sabah, S. K., Al-Marwani, S., Almazan, J. U., Poddighe, D., Al-Mekhlafi, H. M., Ariffin, H., Lim, L., Bandyopadhyay, S., Basnyat, B., Maude, R. J., Bennett, D. A., Browne, A. J., Dolecek, C., Dunachie, S. J., Newton, C. R. J., Rodriguez, J. A. B., Kheirallah, K. A., Alonso, N., Bensenor, I. M., Brunoni, A. R., Castaldelli-Maia, J., Peres, M. F. P., Wang, Y., Alqahtani, J. S., Alqutaibi, A., Altaf, A., Alvi, F. J., Nargus, S., Arooj, M., Latif, M., Shahid, S., Shahid, W., Ashraf, M., Riaz, M. A., Al-Tawfiq, J. A., Alwafi, H., Rehman, F., Al-Worafi, Y. M., Aly, H., Ali, A. H., Amare, A., Gill, T. K., Yadav, L., Noubiap, J., Opio, J., Mengesha, E. W., Ameyaw, E. K., Amhare, A., Lin, S., Amin, T. T., Elhabashy, H. R., Hassan, A., Dehkordi, J. A., Kabir, H., Amiri, S., Amugsi, D. A., Wado, Y. D., Amzat, J., Bello, M. B., Shittu, A., Aruleba, I. T., Ancuceanu, R., Andrei, C., Florin, B. T., Negoi, I., Serban, D., Hostiuc, M., Hostiuc, S., Matei, C. N., Negoi, R. I., Anderlini, D., Begum, T., Kanmiki, E., Maravilla, J. C., Khan, A., Moni, M., Lalloo, R., McGrath, J. J., Veerman, L. J., Andrade, P. P., Busse, R., Mohammed, S., Andrei, T., Herteliu, C., Mirica, A., Otoiu, A., Petcu, I., Dima, A., Stefan, S., Angappan, D., Anil, A., Charan, J., Shamim, M., Singh, S., Varthya, S. B., Baskaran, P., Bhardwaj, P., Bhardwaj, N., Dixit, S. G., Krishna, H., Nayyar, A. K., Choudhary, R., Dixit, A., Misra, S., Mittal, M., Saravanan, A., Singh, M., Ram, P., Anjum, A., Antriyandarti, E., Anwar, S., Anyasodor, A. E., Appiah, S., Boampong, M. S., Aqeel, M., Arabloo, J., Eghdami, S., Panahi, P., Kabir, A., Salahi, S., Behnagh, A. K., Kasraei, H., Khodadoust, E., Latifinaibin, K., Moradi-Lakeh, M., Toroudi, H. P., Sarveazad, A., Zahedi, M., Moradi, M., Arab-Zozani, M., Ghalibaf, A. M., Rajabpour-Sanati, A., Arafat, M., Araújo, A. M., Belo, L., Carvalho, F., Costa, V. M., da Silva, D. D., Silva, J. P., Carvalho, M., Cruz-Martins, N., Freitas, A., Vieira, R. J., Pinheiro, M., Ribeiro, A., Aremu, A., Odetokun, I. A., Aripov, T., Armocida, B., Unim, B., Sabbatucci, M., Artamonov, A. A., Artanti, K. D., Efendi, F., Purnobasuki, H., Wulandari, R. D., Arulappan, J., Chavula, M. P., Edvardsson, D., Orru, H., Fattahi, H., Asika, M. O., Onwujekwe, O. E., Atout, M. M. W., Atreya, A., Attia, S., Aujayeb, A., Avan, A., Hachinski, V., Stranges, S., Bolarinwa, O. A., Ginindza, T. G., Ogunsakin, R. E., Quintanilla, B. A., Rahman, M., Ayuso-Mateos, J. L., Ortiz, A., Soriano, J. B., Catalá-López, F., Aziz, S., Azzam, A. Y., Babashahi, M., Bayati, M., Kouhanjani, M. F., Fazeli, P., Karajizadeh, M., Ghahramani, S., Sarikhani, Y., Shahabi, S., Iravanpour, F., Jafarinia, M., Oliaee, R. T., Ravangard, R., Razeghian-Jahromi, I., Roshanzamir, S., Mansoori, Y., Bakkannavar, S. M., Nayak, V. C., Holla, R., Kamath, A., Rao, M., Ligade, V. S., Rao, C. R., Shetty, R. S., Rao, I., Reshmi, B., Badar, M., Badawi, A., Bhutta, Z. A., Chattu, V., Malhotra, A. K., Mostofinejad, A., Shakil, H., Badiye, A. D., Bansal, H., Kapoor, N., Baghdadi, S., Bagherieh, S., Fatehizadeh, A., Mehrabani-Zeinabad, K., Sadeghi, M., Mirmosayyeb, O., Saber, K., Shafaat, A., Bahadorikhalili, S., Bai, J., Yu, C., Bai, R., Baker, J. L., Bako, A. T., Makram, O. M., Balakrishnan, S., Balogun, S. A., Singh, A., Tian, J., Jatau, A., Baltatu, O. C., Baltatu, O., Campos, L. A., Bam, K., Olaiya, M. T., Bhandari, D., Dalli, L. L., Banach, M., Banik, B., Banik, P. C., Barati, S., Saeedi, M., Bardhan, M., Barker-Collo, S. L., Beyene, K. A., Barone-Adesi, F., Barr, R. D., Kurmi, O. P., Mannan, F., Olagunju, A. T., Barrero, L. H., Basharat, Z., Bashir, A. I. J., Bashiru, H. A., Folayan, M. O., Bassat, Q., Basso, J. D., Silva, S., Rodrigues, M., Basu, S., Batra, K., Batra, R., Sharma, M., Baune, B. T., Bedi, N., Ghailan, K. Y., Khan, M., Halboub, E. S., Shanawaz, M., Sayeed, A., Siraj, M., Behboudi, E., Soleimani, H., Beiranvand, M., Ramirez, D. F. B., Malagón-Rojas, J. N., Belgaumi, U. I., Bello, A. K., Ebenezer, O., Eboreime, E., Umair, M., Beloukas, A., Lunevicius, R., Bendak, S., Benzian, H., Friedman, S. D., Peprah, E. K., Berezvai, Z., Berman, A. E., Bermudez, A. C., Loreche, A., Liu, S., Mohamed, M. F. H., Bettencourt, P. J. G., Bhagat, D. S., Bhagavathula, A. S., Bhala, N., Dehbandi, R., Glasbey, J. C., Bhalla, A., Marasini, B. P., Paudel, U., Poudel, L., Bhardwaj, P. V., Bhargava, A., Kahe, F., Bhaskar, S., Bhat, V., Bhatti, G. K., Kalra, S., Bhatti, J. S., Senapati, S., Bhatti, M. S., Bhatti, R., Das, J. K., Bikbov, B., Bintoro, B., Bisulli, F., Golinelli, D., Guicciardi, S., Lenzi, J., Mazzotti, A., Muccioli, L., Sanmarchi, F., Violante, F. S., Biswas, A., Dhali, A., Biswas, R., Chen, L., Driscoll, T. R., Tang, H. K., Islam, S., Kandel, H., You, Y., Leigh, J., Singh, B. B., Visontay, R., Bitaraf, S., Kaydi, N., Eini, E., Khafaie, M. A., Sadeghian, S., Bjørge, T., Dadras, O., Wojewodzic, M. W., Bodolica, V., Bonny, A., Bora, K., Basara, B. B., Francis, K. L., Kerr, J. A., Carvajal, A. B., Bouaoud, S., Ouyahia, A., Boudalia, S., Lanfranchi, F., Bragazzi, N. L., Braithwaite, D., Ding, D. D., Karanth, S. D., Naghavi, P., Brenner, H., Britton, G., Bulamu, N. B., Bulto, L. N., Foley, K. M., Jemere, D., Kaambwa, B., Mpundu-Kaambwa, C., Buonsenso, D., Villani, L., Nagaraja, S. B., Butt, Z. A., Cai, T., Calina, D., Cámera, L. A., Campos-Nonato, I. R., Denova-Gutiérrez, E., Ortega-Altamirano, D. V., Rios-Blancas, M., Pando-Robles, V., Cao, C., Cardenas, C. A., Cárdenas, R., Carreras, G., Carugno, A., Castañeda-Orjuela, C. A., Castelpietra, G., Catapano, A. L., Damiani, G., Vecchia, C. L., Caye, A., Duncan, B. B., Schmidt, M. I., Hugo, F. N., Cembranel, F., Cenderadewi, M., Emeto, T. I., Obamiro, K. O., Cerin, E., Poudel, G. R., Guo, C., Sarkar, C., Yip, P., Cevik, M., Chacón-Uscamaita, P. R., Chirinos-Caceres, J. L., Chakraborty, C., Chan, J., Chang, C., Douiri, A., Wafa, H. 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- Abstract
Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, ant
- Published
- 2024
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7. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
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Mirza-Aghazadeh-Attari, Mohammad, Mirzaei, Maryam, Misgana, Tadesse, Misra, Sanjeev, Mitchell, Philip B, Mithra, Prasanna, Mittal, Chaitanya, Mittal, Madhukar, Moazen, Babak, Mohamed, Ahmed Ismail, Mohamed, Jama, Mohamed, Mouhand F H, Mohamed, Nouh Saad, Mohammad-Alizadeh-Charandabi, Sakineh, Mohammadi, Soheil, Mohammadian-Hafshejani, Abdollah, Mohammad-pour, Saeed, Mohammadshahi, Marita, Mohammed, Mustapha, Mohammed, Salahuddin, Mohammed, Shafiu, Mojiri-forushani, Hoda, Mokdad, Ali H, Mokhtarzadehazar, Peyman, Momenzadeh, Kaveh, Momtazmanesh, Sara, Monasta, Lorenzo, Moni, Mohammad Ali, Montazeri, Fateme, Moodi Ghalibaf, AmirAli, Moradi, Maryam, Moradi, Yousef, Moradi-Lakeh, Maziar, Moradinazar, Mehdi, Moradpour, Farhad, Moraga, Paula, Morawska, Lidia, Moreira, Rafael Silveira, Morovatdar, Negar, Morrison, Shane Douglas, Morze, Jakub, Mosaddeghi Heris, Reza, Mosser, Jonathan F, Mossialos, Elias, Mostafavi, Hakimeh, Mostofinejad, Amirmahdi, Mougin, Vincent, Mouodi, Simin, Mousavi, Parsa, Mousavi, Seyed Ehsan, Mousavi Khaneghah, Amin, Mpundu-Kaambwa, Christine, Mrejen, Matías, Mubarik, Sumaira, Muccioli, Lorenzo, Mueller, Ulrich Otto, Mughal, Faraz, Mukherjee, Sumoni, Mukoro, George Duke, Mulita, Admir, Mulita, Francesk, Muniyandi, Malaisamy, Munjal, Kavita, Musaigwa, Fungai, Musallam, Khaled M, Mustafa, Ghulam, Muthu, Sathish, Muthupandian, Saravanan, Myung, Woojae, Nabhan, Ashraf F, Nafukho, Fredrick Muyia, Nagarajan, Ahamarshan Jayaraman, Naghavi, Mohsen, Naghavi, Pirouz, Naik, Ganesh R, Naik, Gurudatta, Naimzada, Mukhammad David, Nair, Sanjeev, Nair, Tapas Sadasivan, Najmuldeen, Hastyar Hama Rashid, Naldi, Luigi, Nangia, Vinay, Nargus, Shumaila, Nascimento, Bruno Ramos, Nascimento, Gustavo G, Naser, Abdallah Y, Nasiri, Mohammad Javad, Natto, Zuhair S, Nauman, Javaid, Naveed, Muhammad, Nayak, Biswa Prakash, Nayak, Vinod C, Nayyar, Ashish Kumar, Nazri-Panjaki, Athare, Negash, Hadush, Negero, Amayu Kumesa, Negoi, Ionut, Negoi, Ruxandra Irina, Negru, Serban Mircea, Nejadghaderi, Seyed Aria, Nejjari, Chakib, Nematollahi, Mohammad Hadi, Nena, Evangelia, Nepal, Samata, Nesbit, Olivia D, Newton, Charles Richard James, Ngunjiri, Josephine W, Nguyen, Dang H, Nguyen, Phat Tuan, Nguyen, Phuong The, Nguyen, Tuan Thanh, Nguyen, Van Thanh, Nigatu, Yeshambel T, Nikolouzakis, Taxiarchis Konstantinos, Nikoobar, Ali, Nikpoor, Amin Reza, Nizam, Muhammad A, Nomura, Shuhei, Noreen, Mamoona, Noroozi, Nafise, Norouzian Baghani, Abbas, Norrving, Bo, Noubiap, Jean Jacques, Novotney, Amanda, Nri-Ezedi, Chisom Adaobi, Ntaios, George, Ntsekhe, Mpiko, Nuñez-Samudio, Virginia, Nurrika, Dieta, Oancea, Bogdan, Obamiro, Kehinde O, Odetokun, Ismail A, Ofakunrin, Akinyemi O D, Ogunsakin, Ropo Ebenezer, Oguta, James Odhiambo, Oh, In-Hwan, Okati-Aliabad, Hassan, Okeke, Sylvester Reuben, Okekunle, Akinkunmi Paul, Okidi, Lawrence, Okonji, Osaretin Christabel, Okwute, Patrick Godwin, Olagunju, Andrew T, Olaiya, Muideen Tunbosun, Olanipekun, Titilope O, Olatubi, Matthew Idowu, Olivas-Martinez, Antonio, Oliveira, Gláucia Maria Moraes, Oliver, Susan, Olorukooba, Abdulhakeem Abayomi, Olufadewa, Isaac Iyinoluwa, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oluwafemi, Yinka Doris, Oluwatunase, Gideon Olamilekan, Omar, Hany A, Omer, Goran Latif, Ong, Sokking, Onwujekwe, Obinna E, Onyedibe, Kenneth Ikenna, Opio, John Nelson, Ordak, Michal, Orellana, E Roberto, Orisakwe, Orish Ebere, Orish, Verner N, Orru, Hans, Ortega-Altamirano, Doris V, Ortiz, Alberto, Ortiz-Brizuela, Edgar, Ortiz-Prado, Esteban, Osuagwu, Uchechukwu Levi, Otoiu, Adrian, Otstavnov, Nikita, Ouyahia, Amel, Ouyang, Guoqing, Owolabi, Mayowa O, Oyeyemi, Ifeoluwa Temitayo, Oyeyemi, Oyetunde T, Ozten, Yaz, P A, Mahesh Padukudru, Padubidri, Jagadish Rao, Pahlavikhah Varnosfaderani, Mahsa, Pal, Pramod Kumar, Palicz, Tamás, Palladino, Claudia, Palladino, Raffaele, Palma-Alvarez, Raul Felipe, Pana, Adrian, Panahi, Parsa, Pandey, Ashok, Pandi-Perumal, Seithikurippu R, Pando-Robles, Victoria, Pangaribuan, Helena Ullyartha, Panos, Georgios D, Pantazopoulos, Ioannis, Papadopoulou, Paraskevi, Pardhan, Shahina, Parikh, Romil R, Park, Seoyeon, Parthasarathi, Ashwaghosha, Pashaei, Ava, Pasupula, Deepak Kumar, Patel, Jenil R, Patel, Sangram Kishor, Pathan, Aslam Ramjan, Patil, Ashlesh, Patil, Shankargouda, Patoulias, Dimitrios, Patthipati, Venkata Suresh, Paudel, Uttam, Pawar, Shrikant, Pazoki Toroudi, Hamidreza, Pease, Spencer A, Peden, Amy E, Pedersini, Paolo, Peng, Minjin, Pensato, Umberto, Pepito, Veincent Christian Filipino, Peprah, Emmanuel K, Pereira, Gavin, Pereira, Jeevan, Pereira, Marcos, Peres, Mario F P, Perianayagam, Arokiasamy, Perico, Norberto, Petcu, Ionela-Roxana, Petermann-Rocha, Fanny Emily, Pezzani, Raffaele, Pham, Hoang Tran, Phillips, Michael R, Pierannunzio, Daniela, Pigeolet, Manon, Pigott, David M, Pilgrim, Thomas, Pinheiro, Marina, Piradov, Michael A, Plakkal, Nishad, Plotnikov, Evgenii, Poddighe, Dimitri, Pollner, Peter, Poluru, Ramesh, Pond, Constance Dimity, Postma, Maarten J, Poudel, Govinda Raj, Poudel, Lisasha, Pourali, Ghazaleh, Pourtaheri, Naeimeh, Prada, Sergio I, Pradhan, Pranil Man Singh, Prajapati, Vijay Kumar, Prasad, Chandra P, Prasad, Manya, Prashant, Akila, Prates, Elton Junio Sady, Purnobasuki, Hery, Purohit, Bharathi M, Puvvula, Jagadeesh, Qaisar, Rizwan, Qasim, Nameer Hashim, Qattea, Ibrahim, Qian, Gangzhen, Quan, Nguyen Khoi, Radfar, Amir, Radhakrishnan, Venkatraman, Raee, Pourya, Raeisi Shahraki, Hadi, Rafiei Alavi, Seyedeh Niloufar, Rafique, Ibrar, Raggi, Alberto, Rahim, Fakher, Rahman, Md Mosfequr, Rahman, Mosiur, Rahman, Muhammad Aziz, Rahman, Tafhimur, Rahmani, Amir Masoud, Rahmani, Shayan, Rahnavard, Niloufar, Rai, Pramila, Rajaa, Sathish, Rajabpour-Sanati, Ali, Rajput, Prashant, Ram, Prasanna, Ramadan, Hazem, Ramasamy, Shakthi Kumaran, Ramazanu, Sheena, Rana, Juwel, Rana, Kritika, Ranabhat, Chhabi Lal, Rancic, Nemanja, Rani, Smitha, Ranjan, Shubham, Rao, Chythra R, Rao, Indu Ramachandra, Rao, Mithun, Rao, Sowmya J, Rasali, Drona Prakash, Rasella, Davide, Rashedi, Sina, Rashedi, Vahid, Rashid, Ahmed Mustafa, Rasouli-Saravani, Ashkan, Rastogi, Prateek, Rasul, Azad, Ravangard, Ramin, Ravikumar, Nakul, Rawaf, David Laith, Rawaf, Salman, Rawassizadeh, Reza, Razeghian-Jahromi, Iman, Reddy, Murali Mohan Rama Krishna, Redwan, Elrashdy Moustafa Mohamed, Rehman, Faizan Ur, Reiner Jr, Robert C, Remuzzi, Giuseppe, Reshmi, Bhageerathy, Resnikoff, Serge, Reyes, Luis Felipe, Rezaee, Malihe, Rezaei, Negar, Rezaei, Nima, Rezaeian, Mohsen, Riaz, Mavra A, Ribeiro, Ana Isabel, Ribeiro, Daniel Cury, Rickard, Jennifer, Rios-Blancas, Maria Jesus, Robinson-Oden, Hannah Elizabeth, Rodrigues, Mónica, Rodriguez, Jefferson Antonio Buendia, Roever, Leonardo, Rohilla, Ravi, Rohloff, Peter, Romadlon, Debby Syahru, Ronfani, Luca, Roshandel, Gholamreza, Roshanzamir, Sharareh, Rostamian, Morteza, Roy, Bedanta, Roy, Priyanka, Rubagotti, Enrico, Rumisha, Susan Fred, Rwegerera, Godfrey M, Rynkiewicz, Andrzej, S, Manjula, S N, Chandan, S Sunnerhagen, Katharina, Saad, Aly M A, Sabbatucci, Michela, Saber, Korosh, Saber-Ayad, Maha Mohamed, Sacco, Simona, Saddik, Basema, Saddler, Adam, Sadee, Bashdar Abuzed, Sadeghi, Ehsan, Sadeghi, Masoumeh, Sadeghian, Saeid, Saeed, Umar, Saeedi, Maryam, Safi, Sare, Sagar, Rajesh, Saghazadeh, Amene, Saheb Sharif-Askari, Narjes, Sahoo, Soumya Swaroop, Sahraian, Mohammad Ali, Sajedi, Seyed Aidin, Sajid, Mirza Rizwan, Sakshaug, Joseph W, Salahi, Saina, Salahi, Sarvenaz, Salamati, Payman, Salami, Afeez Abolarinwa, Salaroli, Luciane B, Saleh, Mohamed A, Salehi, Sana, Salem, Marwa Rashad, Salem, Mohammed Z Y, Salimi, Sohrab, Samadi Kafil, Hossein, Samadzadeh, Sara, Samara, Kamel A, Samargandy, Saad, Samodra, Yoseph Leonardo, Samuel, Vijaya Paul, Samy, Abdallah M, Sanabria, Juan, Sanadgol, Nima, Sanganyado, Edmond, Sanjeev, Rama Krishna, Sanmarchi, Francesco, Sanna, Francesca, Santri, Ichtiarini Nurullita, Santric-Milicevic, Milena M, Sarasmita, Made Ary, Saravanan, Aswini, Saravi, Babak, Sarikhani, Yaser, Sarkar, Chinmoy, Sarmiento-Suárez, Rodrigo, Sarode, Gargi Sachin, Sarode, Sachin C, Sarveazad, Arash, Sathian, Brijesh, Sathish, Thirunavukkarasu, Sattin, Davide, Saulam, Jennifer, Sawyer, Susan M, Saxena, Sonia, Saya, Ganesh Kumar, Sayadi, Yaser, Sayeed, Abu, Sayeed, Md Abu, Saylan, Mete, Scarmeas, Nikolaos, Schaarschmidt, Benedikt Michael, Schlee, Winfried, Schmidt, Maria Inês, Schuermans, Art, Schwebel, David C, Schwendicke, Falk, Šekerija, Mario, Selvaraj, Siddharthan, Semreen, Mohammad H, Senapati, Sabyasachi, Sengupta, Pallav, Senthilkumaran, Subramanian, Sepanlou, Sadaf G, Serban, Dragos, Sertsu, Addisu, Sethi, Yashendra, SeyedAlinaghi, SeyedAhmad, Seyedi, Seyed Arsalan, Shafaat, Amir, Shafaat, Omid, Shafie, Mahan, Shafiee, Arman, Shah, Nilay S, Shah, Pritik A, Shahabi, Saeed, Shahbandi, Ataollah, Shahid, Izza, Shahid, Samiah, Shahid, Wajeehah, Shahwan, Moyad Jamal, Shaikh, Masood Ali, Shakeri, Alireza, Shakil, Husain, Sham, Sunder, Shamim, Muhammad Aaqib, Shams-Beyranvand, Mehran, Shamshad, Hina, Shamshirgaran, Mohammad Ali, Shamsi, Mohammad Anas, Shanawaz, Mohd, Shankar, Abhishek, Sharfaei, Sadaf, Sharifan, Amin, Shariff, Mariam, Sharifi-Rad, Javad, Sharma, Manoj, Sharma, Rajesh, Sharma, Saurab, Sharma, Vishal, Shastry, Rajesh P, Shavandi, Amin, Shaw, David H, Shayan, Amir Mehdi, Shehabeldine, Amr Mohamed Elsayed, Sheikh, Aziz, Sheikhi, Rahim Ali, Shen, Jiabin, Shenoy, Manjunath Mala, Shetty, B Suresh Kumar, Shetty, Ranjitha S, Shey, Robert Adamu, Shiani, Amir, Shibuya, Kenji, Shiferaw, Desalegn, Shigematsu, Mika, Shin, Jae Il, Shin, Min-Jeong, Shiri, Rahman, Shirkoohi, Reza, Shittu, Aminu, Shiue, Ivy, Shivakumar, K M, Shivarov, Velizar, Shool, Sina, Shrestha, Sunil, Shuja, Kanwar Hamza, Shuval, Kerem, Si, Yafei, Sibhat, Migbar Mekonnen, Siddig, Emmanuel Edwar, Sigfusdottir, Inga Dora, Silva, João Pedro, Silva, Luís Manuel Lopes Rodrigues, Silva, Soraia, Simões, Jorge Piano, Simpson, Colin R, Singal, Anjali, Singh, Abhinav, Singh, Aditya, Singh, Ambrish, Singh, Balbir Bagicha, Singh, Baljinder, Singh, Mahendra, Singh, Mayank, Singh, Narinder Pal, Singh, Paramdeep, Singh, Surjit, Siraj, Md Shahjahan, Sitas, Freddy, Sivakumar, Shravan, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Sleet, David A, Slepak, Erica Leigh N, Sohrabi, Hanye, Soleimani, Hamidreza, Soliman, Sameh S M, Solmi, Marco, Solomon, Yonatan, Song, Yimeng, Sorensen, Reed J D, Soriano, Joan B, Soyiri, Ireneous N, Spartalis, Michael, Sreeramareddy, Chandrashekhar T, Starnes, Joseph R, Starodubov, Vladimir I, Starodubova, Antonina V, Stefan, Simona Cătălina, Stein, Dan J, Steinbeis, Fridolin, Steiropoulos, Paschalis, Stockfelt, Leo, Stokes, Mark A, Stortecky, Stefan, Stranges, Saverio, Stroumpoulis, Konstantinos, Suleman, Muhammad, Suliankatchi Abdulkader, Rizwan, Sultana, Abida, Sun, Jing, Sunkersing, David, Susanty, Sri, Swain, Chandan Kumar, Sykes, Bryan L, Szarpak, Lukasz, Szeto, Mindy D, Szócska, Miklós, Tabaee Damavandi, Payam, Tabatabaei Malazy, Ozra, Tabatabaeizadeh, Seyed-Amir, Tabatabai, Shima, Tabb, Karen M, Tabish, Mohammad, Taborda-Barata, Luis M, Tabuchi, Takahiro, Tadesse, Birkneh Tilahun, Taheri, Amirmasoud, Taheri Abkenar, Yasaman, Taheri Soodejani, Moslem, Taherkhani, Amir, Taiba, Jabeen, Tajbakhsh, Ardeshir, Talaat, Iman M, Talukder, Ashis, Tamuzi, Jacques Lukenze, Tan, Ker-Kan, Tang, Haosu, Tang, Hong K, Tat, Nathan Y, Tat, Vivian Y, Tavakoli Oliaee, Razieh, Tavangar, Seyed Mohammad, Taveira, Nuno, Tebeje, Tsion Mulat, Tefera, Yibekal Manaye, Teimoori, Mojtaba, Temsah, Mohamad-Hani, Temsah, Reem Mohamad Hani, Teramoto, Masayuki, Tesfaye, Solomon Hailemariam, Thangaraju, Pugazhenthan, Thankappan, Kavumpurathu Raman, Thapa, Rajshree, Thapar, Rekha, Thomas, Nihal, Thrift, Amanda G, Thum, Chern Choong Chern, Tian, Jing, Tichopad, Ales, Ticoalu, Jansje Henny Vera, Tiruye, Tenaw Yimer, Tohidast, Seyed Abolfazl, Tonelli, Marcello, Touvier, Mathilde, Tovani-Palone, Marcos Roberto, Tram, Khai Hoan, Tran, Nghia Minh, Trico, Domenico, Trihandini, Indang, Tromans, Samuel Joseph, Truong, Vien T, Truyen, Thien Tan Tri Tai, Tsermpini, Evangelia Eirini, Tumurkhuu, Munkhtuya, Tung, Kang, Tyrovolas, Stefanos, Ubah, Chukwudi S, Udoakang, Aniefiok John, Udoh, Arit, Ulhaq, Inam, Ullah, Saeed, Ullah, Sana, Umair, Muhammad, Umar, Tungki Pratama, Umeokonkwo, Chukwuma David, Umesh, Anushri, Unim, Brigid, Unnikrishnan, Bhaskaran, Upadhyay, Era, Urso, Daniele, Vacante, Marco, Vahdani, Amir Mohammad, Vaithinathan, Asokan Govindaraj, Valadan Tahbaz, Sahel, Valizadeh, Rohollah, Van den Eynde, Jef, Varavikova, Elena, Varga, Orsolya, Varma, Siddhartha Alluri, Vart, Priya, Varthya, Shoban Babu, Vasankari, Tommi Juhani, Veerman, Lennert J, Venketasubramanian, Narayanaswamy, Venugopal, Deneshkumar, Verghese, Nicholas Alexander, Verma, Madhur, Verma, Pratibha, Veroux, Massimiliano, Verras, Georgios-Ioannis, Vervoort, Dominique, Vieira, Rafael José, Villafañe, Jorge Hugo, Villani, Leonardo, Villanueva, Gabriela Ines, Villeneuve, Paul J, Violante, Francesco S, Visontay, Rachel, Vlassov, Vasily, Vo, Bay, Vollset, Stein Emil, Volovat, Simona Ruxandra, Volovici, Victor, Vongpradith, Avina, Vos, Theo, Vujcic, Isidora S, Vukovic, Rade, Wado, Yohannes Dibaba, Wafa, Hatem A, Waheed, Yasir, Wamai, Richard G, Wang, Cong, Wang, Denny, Wang, Fang, Wang, Shu, Wang, Song, Wang, Yanzhong, Wang, Yuan-Pang, Ward, Paul, Watson, Stefanie, Weaver, Marcia R, Weerakoon, Kosala Gayan, Weiss, Daniel J, Weldemariam, Abrha Hailay, Wells, Katherine M, Wen, Yi Feng, Werdecker, Andrea, Westerman, Ronny, Wickramasinghe, Dakshitha Praneeth, Wickramasinghe, Nuwan Darshana, Wijeratne, Tissa, Wilson, Shadrach, Wojewodzic, Marcin W, Wool, Eve E, Woolf, Anthony D, Wu, Dongze, Wulandari, Ratna Dwi, Xiao, Hong, Xu, Bin, Xu, Xiaoyue, Yadav, Lalit, Yaghoubi, Sajad, Yang, Lin, Yano, Yuichiro, Yao, Yao, Ye, Pengpeng, Yesera, Gesila Endashaw, Yesodharan, Renjulal, Yesuf, Subah Abderehim, Yiğit, Arzu, Yiğit, Vahit, Yip, Paul, Yon, Dong Keon, Yonemoto, Naohiro, You, Yuyi, Younis, Mustafa Z, Yu, Chuanhua, Zadey, Siddhesh, Zadnik, Vesna, Zafari, Nima, Zahedi, Mohammad, Zahid, Muhammad Nauman, Zahir, Mazyar, Zakham, Fathiah, Zaki, Nazar, Zakzuk, Josefina, Zamagni, Giulia, Zaman, Burhan Abdullah, Zaman, Sojib Bin, Zamora, Nelson, Zand, Ramin, Zandi, Milad, Zandieh, Ghazal G Z, Zanghì, Aurora, Zare, Iman, Zastrozhin, Mikhail Sergeevich, Zeariya, Mohammed G M, Zeng, Youjie, Zhai, Chunxia, Zhang, Chen, Zhang, Haijun, Zhang, Hongwei, Zhang, Yunquan, Zhang, Zhaofeng, Zhang, Zhenyu, Zhao, Hanqing, Zhao, Yang, Zhao, Yong, Zheng, Peng, Zhong, Chenwen, Zhou, Juexiao, Zhu, Bin, Zhu, Zhaohua, Ziaeefar, Pardis, Zielińska, Magdalena, Zou, Zhiyong, Zumla, Alimuddin, Zweck, Elric, Zyoud, Samer H, Lim, Stephen S, and Murray, Christopher J L
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- 2024
8. Quantification of Phytochemical Constituents of Ethanol Yellow Spondias mombin Leaf Extract in Ogba/Ebgema/Ndoni Local Government Area of Rivers State, Nigeria.
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EZE, U. S., OBI, C., and JAMES, A. O.
- Abstract
Phytochemicals are naturally occurring compounds in plants that have been shown to possess various medicinal activities, making them of great interest for their potential health benefits. Hence, the objective of this paper was to investigate by quantifying the phytochemical constituents of ethanol leaf extract of yellow mombin fruit (Spondias Mombin) collected from Omoku, in Ogba/Ebgema/Ndoni Local Government Area of Rivers State, Nigeria using appropriated standard methods. The data obtained show that the concentration flavonoid in the ethanol leaf extract of yellow mombin fruit (Spondias Mombin) was 144.34 mg/100g, while Alkaloid, Cyanogenic glycosides and Phenolic content were 169.42 mg/100g, 123.74 mg/100g and 218.06 mg/100g respectively. These results indicate that Spondias mombin leaves are rich in bioactive compounds, particularly phenols, which are known for their potent antioxidant properties. The significant presence of alkaloids suggests potential antimicrobial activity, while the flavonoids contribute to anti-inflammatory benefits. Cyanogenic glycosides, although present in lower concentration, necessitate careful consideration due to their potential toxicity. Overall, this quantitative analysis supports the traditional use of Spondias mombin in herbal medicine and underscores the need for further research to explore its full pharmacological potential and ensure safe usage. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Synthesis, characterization, DFT studies and molecular docking investigation of 2-oxo-ethyl piperidine pentanamide-derived sulfonamides as anti-diabetic agents
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Fredrick C. Asogwa, Ekoh C. Ogechi, H. Louis, Ugwu D. Izuchukwu, Chioma G. Apebende, Eze U. Florence, Martins C. Ekeleme, Ezugwu A. James, Onyinye J. Ikenyirimba, Alexander I. Ikeuba, Aniekan E. Owen, and Okoro U. Chris
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Anti-diabetic ,Synthesis ,Sulfonamides ,Piperidine ,DFT ,Molecular docking ,Chemistry ,QD1-999 - Abstract
The present study is focused on the synthesis, characterization, DFT Studies, and in silico biological evaluation of novel benzenesulfonamides as antidiabetic agents. The compounds were synthesized and characterized experimentally using the NMR, FT-IR and HRMS while the molecular electronic structure properties were investigated using DFT-based theoretical methods at the M06-2X/6–311++G (d, p) level of theory. The results of the calculated vibrational energies were in perfect agreement with those of the experimental frequencies for different functional groups. The natural bond orbital (NBO) analysis was also carried out to study the intramolecular charge transfer interactions and energies of stabilization. Molecular docking simulation showed that the compounds; 3-Methyl-2-(4-methylphenylsulfonamido)-N-(2-oxo-2(piperidin-1-yl) ethyl) pentanamide (MMOPEP), 3-Methyl-N-(2-oxo-2-(piperidin-1-yl)ethyl))-2-(phenylsulfonamido)pentanamide (MOPEPP) and, 3-Methyl-2-(4-nitrophenylsulfonamido)-N-(2-oxo-2-(piperidin-1-yl)ethyl)pentanamide (MNOPEP) fitted tightly to the amino acid residues binding sites of insulin inhibiting protein receptors (7m17) with an average binding affinity of −6.9 kcal/mol, −6.6 kcal/mol, −6.7 kcal/mol respectively, thereby stimulating the release of insulin from functioning pancreatic beta cells which will in turn, lower blood glucose. This study provides a platform for scrutiny and clinical trials of benzenesulfonamide-based drugs as antidiabetic agents.
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- 2022
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10. A-035 Association between Obesity and Prostate Specific Antigen level in Diabetes Mellitus Type2
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Ugwunna, O C, primary, Okafor, E N, additional, Ugwunna, N C, additional, Chukwukelu, E E, additional, Eze, U A, additional, Uzoigwe, S O, additional, and Aniogo, E C, additional
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- 2023
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11. Economic and feasibility comparison of the dRIT and DFA for decentralized rabies diagnosis in resource-limited settings: The use of Nigerian dog meat markets as a case study.
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Eze U Ukamaka, Andre Coetzer, Terence P Scott, Boniface M Anene, Romanus C Ezeokonkwo, Chika I Nwosuh, Louis H Nel, and Claude T Sabeta
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Arctic medicine. Tropical medicine ,RC955-962 ,Public aspects of medicine ,RA1-1270 - Abstract
BACKGROUND:Rabies lyssavirus (RABV) is the aetiologic agent of rabies, a disease that is severely underreported in Nigeria as well as elsewhere in Africa and Asia. Despite the role that rabies diagnosis plays towards elucidating the true burden of the disease, Nigeria-a country of 180 million inhabitants-has a limited number of diagnostic facilities. In this study, we sought to investigate two of the World Organization for Animal Health (OIE)-recommended diagnostic assays for rabies-viz; the direct fluorescent antibody test (DFA) and the direct rapid immunohistochemical test (dRIT) in terms of their relative suitability in resource-limited settings. Our primary considerations were (1) the financial feasibility for implementation and (2) the diagnostic efficacy. As a case study, we used suspect rabies samples from dog meat markets in Nigeria. METHODS/PRINCIPAL FINDINGS:By developing a simple simulation framework, we suggested that the assay with the lowest cost to implement and routinely use was the dRIT assay. The costs associated with the dRIT were lower in all simulated scenarios, irrespective of the number of samples tested per year. In addition to the cost analysis, the diagnostic efficacies of the two assays were evaluated. To do this, a cohort of DFA-positive and -negative samples collected from dog meat markets in Nigeria were initially diagnosed using the DFA in Nigeria and subsequently sent to South Africa for diagnostic confirmation. In South Africa, all the specimens were re-tested with the DFA, the dRIT and a quantitative real-time polymerase chain reaction (qRT-PCR). In our investigation, discrepancies were observed between the three diagnostic assays; with the incongruent results being resolved by means of confirmatory testing using the heminested reverse transcription polymerase reaction and sequencing to confirm that they were not contamination. CONCLUSIONS/SIGNIFICANCE:The data obtained from this study suggested that the dRIT was not only an effective diagnostic assay that could be used to routinely diagnose rabies, but that the assay was also the most cost-effective option among all of the OIE recommended methods. In addition, the results of our investigation confirmed that some of the dogs slaughtered in dog markets were rabies-positive and that the markets posed a potential public health threat. Lastly, our data showed that the DFA, although regarded as the gold standard test for rabies, has some limitations-particularly at low antigen levels. Based on the results reported here and the current challenges faced in Nigeria, we believe that the dRIT assay would be the most suitable laboratory test for decentralized or confirmatory rabies diagnosis in Nigeria, given its relative speed, accuracy, cost and ease of use.
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- 2020
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12. Antioxidant, antibacterial and antibiofilm activities of ethanol extract of Zapotecca portoricensis roots.
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Eze, U. A., Nwankwuo, I. U., Apeh, O. G., Ezeh, G. C., and Onoja, S. O.
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GAS chromatography/Mass spectrometry (GC-MS) ,PHYTOCHEMICALS ,ANTIOXIDANTS ,PLANT extracts ,REPRODUCTIVE isolation - Abstract
This study evaluated the phytochemical composition, antioxidant, antibacterial and antibiofilm activities of ethanol extract of Zapotecca portoricensis root. The extract was prepared via cold maceration method and gas chromatography-mass spectrometry (GC-MS) was used to determine the phytochemical composition of the extract. The antioxidant activity was evaluated using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and ferric reducing antioxidant power (FRAP) procedures. The antibacterial and antibiofilm activities of the extract were evaluated against clinical isolates of Eschericia coli, Staphylococcus aureus and Salmonella typhi using agar well diffusion technique. The GC-MS analysis showed the presence of seven (7) bioactive compounds. The extract produced concentration dependent increase in the antioxidant values in both the DPPH and FRAP assay protocols. The extract produced concentration-dependent increase in the zone of inhibition against the tested organisms. At 62.5 mg/mL and below concentrations, the zones of inhibition of Z. portoricensis root extract against E. coli and S. aureus were significantly (p < 0.05) lower when compared with the zone of inhibition of Z. portoricensis root extract against S. typhi. The minimum inhibitory concentration (MIC) of Z. portoricensis root extract against E. coil, S. aureus and S. typhi were 31.25, 15.63 and 62.50 mg/mL concentration, respectively. The extract produced concentration-dependent increase in antibiofilm activity. At 7.5 mg/kg, the extract produced 28.87, 34.01 and 66.45% inhibition of biofilm production against S. typhi, E. coli and S. aureus, respectively. The extract possess antioxidant, antibacterial and antibiofilm activities which could be linked to the presence ethyl iso allocholate and hexadecanoic acid. [ABSTRACT FROM AUTHOR]
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- 2023
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13. 1410 Single-cell RNA sequencing reveals POUF51 and HES3 as regulators of the stem cell population in psoriasis
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Eze, U., primary, Cheng, J., additional, Cho, R., additional, and Ghadially, R., additional
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- 2023
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14. Application of 2-D and 3-D Geo-electrical Resistivity Tomography and Geotechnical soil Evaluation for Engineering site Investigation: A Case Study of Okerenkoko Primary School, Warri-Southwest, Delta State, Nigeria
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Eze, U. Stanley, primary, Okiotor, M. Edirin, additional, Ighadalo, J. E., additional, Owonaro, B. Jennife, additional, Saleh, A. Saleh, additional, and Jamiu, A. Sikiru, additional
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- 2023
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15. Factors That Contribute to Research and Publication Output Among Librarians in Nigerian University Libraries
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Ibegbulam, Ijeoma J. and Jacintha, Eze U.
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- 2016
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16. Effect of Processing Methods on Proximate Composition of Cassava Varieties Manihot esculenta (Crantz) Before and After Infestation by Prostephanus truncatus (Horn)
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Eze U. Miriam, N. J. Okonkwo, and Iroka F. Chisom
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Horticulture ,biology ,Manihot ,French horn ,Infestation ,Manihot esculenta ,medicine ,biology.organism_classification ,medicine.disease_cause ,Proximate composition ,Prostephanus truncatus ,Processing methods - Abstract
In Africa, Prostephanus truncatus is a destructive pest of economic importance which has assumed a serious pest status on stored maize and dry cassava chips. This study investigates the effect of processing methods of cassava varieties Manihot esculenta on the proximate composition before and after exposure to P. truncatus. The four cassava varieties used for this study were; TMS 0505, TME 419, NR 8082 and TMS 0581 subjected to two processing method parboiling and plain sun-drying at temperature 28-34oC and relative humidity of 65-75%. The experiment was carried out in a Complete Randomized Design. Proximate composition was carried out to determine the Moisture, Ash, Crude fibre, Fat, Crude Protein and Carbohydrate of the different samples. Analysis of Variance was used for the statistical analysis of the data obtained. The result reveals that the proximate composition of the sundried chips are significant at P
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- 2021
17. Assessment of the Burden and Factors Associated with Missed Opportunities for Vaccination in a South-Western State of Nigeria: Toward Immunization Agenda 2030.
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Eze, U. T., Tanimowo, S. O., Ajadi, A. E., Okeke, C., Ohazurike, C., and Uzochukwu, B. S. C.
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- 2023
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18. Impact of hand washing training on pharmacy students; a quasi-experimental study
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Ogbonna, B.O, Nwanga, K, Maduekwe, H.N, Okpalanma, N.N, Eze, U, Ovwighose, S.O, Okeke, A, Anetoh, M.U, Adenola, U.A, Umeh, I.B, Ejieh, L.I, Nduka, J.I, and Ajagu, N.N
- Subjects
hand washing, impact, assessment, survey, educational workshop, students - Abstract
Background: Globally, poor hand washing practiceshave led to a remarkable increase in the rate ofinfection and spread of infectious diseases. Hands arethe main route of germ transmission during medicalmanagement. Hence, hand washing is an effectivemeasure to prevent the transmission of infectiousdiseases in healthcare. Objective: The study assessed the impact of handwashing training on pharmacy students’ knowledgeof hand washing. Methods: The study employed quasi-experimentalstudy design. Pre-test data collection was carried outwith a structured questionnaire to assess thestudent’s knowledge of hand washing technique atbaseline. This was followed by an educationalworkshop on proper hand washing technique andpost-test data collection using the samequestionnaire. All the students (299) who gave theirinformed consent participated in the study. Meanscore of individual response was computed for thedifferent sections of the questionnaire. Data analysiswas performed using SPSS version 22 computersoftware. Statistical analysis was done using Paired ttest.A value of p4.However, the educational workshop had significantimpact on the students’ hand washing technique inall the three domains assessed with p-values of 0.000for each domain. Conclusion: This study suggests that handwashingtraining had a positive impact on the students’handwashing knowledge.
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- 2022
19. 652 Short cell cycle duration is a phenotype of human epidermal stem cells
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Abegaze, B.H., Eze, U., Xiao, T., Schwab, G., and Ghadially, R.
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- 2024
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20. SA55 Efficacy and Tolerability of Contingency Management and Cognitive-Behavioral Therapy With Pharmacotherapy or Placebo in Managing Stimulant Use Disorder: A Systematic Review and Meta-Analysis
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Eze, U, Ologunowa, A, Ozota, O, Ufuah, U, Oguguo, V, Onyia, I, Sabastine, R, Ifeanyi, R, Salim, J, Obi, O, Asogwa, C, Ononuju, U, Ben-Umeh, K, and Amorha, K
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- 2024
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21. Prevalence and Determinants of Depression among Caregivers of Children with Heart Diseases in Nigeria
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Chika O. Duru, Frances Sam Okpokowuruk, and Eze U. Chikezie
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Community and Home Care ,medicine.medical_specialty ,business.industry ,Medicine ,business ,Psychiatry ,Depression (differential diagnoses) - Abstract
Context: Caregivers of children with heart diseases are faced with the long term care of these children and may suffer psychological illnesses as a result. Aims: To determine the prevalence and determinants of depression among caregivers of children with heart diseases attending two Out-patient clinics in South-South Nigeria. Materials and Methods: It was a cross-sectional study involving the use of the revised Center for Epidemiological Studies Depression (CESD-R) questionnaire. Data were entered into an Excel spreadsheet and analyzed using SPSS 22.0. Results: Ages of the participants ranged from 24 to 59 years with a mean age of 37.49 years (SD 6.973) and majority were female (79.9%). The overall mean CESD-R score was 8.61 (SD 16.18), ranging from 0 to 60. There was a significant difference in the CESD-R scores between male and female participants (t=2.362, p=0.02) with females scoring higher than males (10.24± 17.69 and 2.15± 3.13) respectively. Overall, depression was found among 23(17.1%) participants. Depression was significantly associated with the female sex (x2=7.006, p=0.009), a history of a mental health illness in the past (x2=66.496, p=0.029) and the marital status of the participants (x2=19.776, p=0.05). No significant relationship was found between depression and age, religion, tribe and educational status (p>0.05), history of medical illnesses (x2=53.006, p=0.538) or type of heart disease the children/wards of the participants were being managed for (x2=8.274, p=0.902). Conclusion: The rate of depression among caregivers of children being managed for congenital and acquired heart diseases in this study is significant. It is recommended that caregivers of children with congenital and acquired heart diseases are routinely given relevant psychosocial support to prevent the development of depression. Routine screening for depression and appropriate intervention for those who meet the criteria is also recommended.
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- 2020
22. Effect of Processing Methods on Proximate Composition of Cassava Varieties Manihot esculenta (Crantz) Before and After Infestation by Prostephanus truncatus (Horn)
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Miriam, Eze U., primary, Okonkwo, N. J., primary, and Chisom, Iroka F., primary
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- 2021
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23. Correlation of Intraoperative Cytological and Final Histological Diagnoses: A Retrospective 10-Year Study of Neurosurgical Cases From Ibadan, Nigeria
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Salami, A., Azeez, A., Malomo, A., Oluwasola, A., Adeleye, A., Ogun, G., Adeoye, A., Adeolu, A., Okolo, C., Eze, U., Abdullahi, Y., Lawan, A., Ogunbiyi, J., Akang, E., and Shokunbi, M.
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- 2015
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24. Haematology and serum biochemistry of dogs naturally infected with canine parvovirus-2.
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Ogbu, K. I., Chukwudi, C. I., Tion, M. T., Eze, U. U., Nwosuh, I. C., and Anene, B. M.
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LEUKOCYTE count ,BLOOD cell count ,BONE marrow cells ,INTESTINAL physiology ,BIOCHEMISTRY ,ERYTHROCYTES ,LYMPHOCYTE count - Abstract
Canine parvovirus is a deadly virus affecting the Canid family, causing virus-induced destruction of rapidly dividing haemopoietic precursor cells such as crypts of intestinal epithelial cells, thymus, lymph nodes, bone marrow precursor cells, blood cells and cardiac cells leading to multi-organ dysfunctions. The aim of this study was to determine the haematological, serum biochemical and electrolytic changes associated with canine parvovirus (CPV) -2 infection. An immunochromatographic test was used to differentiate the virus-positive and negative dogs using faecal samples. One hundred and sixty whole blood and serum samples were collected from apparently healthy and CPV-2-positive dogs in Plateau State, Nigeria. Haematological, serum biochemical and electrolytic analyses were done using standard methods. The data obtained were analyzed using descriptive statistics and a student t-test. Significance was accepted at probability values of p < 0.05. The haematological effect of CPV-2 showed a significant (P < 0.05) decrease in mean Packed Cell Volume (PCV), total red blood cell count, haemoglobin concentration, total white blood cell count, neutrophils, lymphocytes and platelet count. In addition, the CPV-2 significantly (P < 0.05) increased the mean aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, urea, creatinine, triglyceride and malondialdehyde, while the mean total protein, sodium, potassium, chloride and cholesterol significantly (P < 0.05) decreased in the infected dogs. From the findings, CPV infection variably and significantly affected some haematological and serum biochemical parameters of infected dogs. Therefore, clinicians should endeavour to incorporate haematinics, haptatonics and immunemodulators during the management of canine parvoviral infection as supportive drugs with fluid therapy to improve the survivability of infected animals. [ABSTRACT FROM AUTHOR]
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- 2022
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25. Assessment of the knowledge of healthcare workers on monkeypox in Nigeria
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Eze, Uche, Okafor, Nnenna, Ozota, Gerald, Nworie, Kelechi, Asogwa, Christian, Richard, Ifeanyi, Ilochonwu, Ann-Pearl, Ezeasor, Samuel, Okorie, Chineye, Ben-Umeh, Kenechukwu, Ezeh, Adaeze, Aboh, Mercy, and Isah, Abdulmuminu
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monkeypox ,healthcare workers ,knowledge ,nigeria ,Medicine ,Public aspects of medicine ,RA1-1270 ,Microbiology ,QR1-502 - Abstract
Background: Monkeypox, a re-emerging zoonotic disease caused by the monkeypox virus (MPXV), poses a public health challenge in Nigeria. To effectively combat this disease, it is essential to assess the knowledge of healthcare workers (HCWs) in Nigeria concerning monkeypox outbreak.Methods: A cross-sectional web-based survey with 609 healthcare workers in Nigeria was conducted using a structured questionnaire to assess their knowledge of monkeypox. Data were coded and analyzed with Microsoft Excel and Python in Anaconda Jupyter Notebook.Results: The majority of respondents (n=318, 52.2%) had good knowledge of MPXV but also had knowledge gaps regarding certain symptoms and disease similarities. Interestingly, respondents were completely unaware of the possibility of sexual transmission of the disease. However, they recognized the possible significant impact of monkeypox on the social and economic lifestyle of Nigerians (n=582, 95.6%, R=21.181, 95% CI: 14.450–31.051). Respondents had mixed knowledge regarding the use of smallpox vaccines and antiviral agents for monkeypox prevention and treatment. Furthermore, a significant proportion (n=526, 86.4%, adjOR=0.159, 95% CI: 0.126–0.201) attributed the outbreak to bioterrorism. The logistic regression highlighted a strong influence of academic qualification, type of healthcare provider, years of experience, and geopolitical zone of practice, on monkeypox knowledge in Nigeria.Conclusion: The study highlights the importance of continuous education for healthcare professionals in Nigeria to improve monkeypox outbreak management. Despite their moderate performance, there are knowledge gaps in critical areas among HCWs, necessitating further research to explore reasons and influencing factors for knowledge levels.
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- 2024
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26. Economic and feasibility comparison of the dRIT and DFA for decentralized rabies diagnosis in resource-limited settings: The use of Nigerian dog meat markets as a case study
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R. C. Ezeokonkwo, Boniface M. Anene, Andre Coetzer, Louis Hendrik Nel, Eze U. Ukamaka, CI Nwosuh, Claude T. Sabeta, and Terence Peter Scott
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RNA viruses ,0301 basic medicine ,Viral Diseases ,RC955-962 ,Artificial Gene Amplification and Extension ,Antibodies, Viral ,Pathology and Laboratory Medicine ,Polymerase Chain Reaction ,Geographical Locations ,0302 clinical medicine ,Animal Products ,Zoonoses ,Arctic medicine. Tropical medicine ,Medicine and Health Sciences ,Medicine ,Dog Diseases ,Mammals ,biology ,Animal health ,Eukaryota ,Agriculture ,Immunohistochemistry ,Veterinary Diagnostics ,Infectious Diseases ,Veterinary Diseases ,Fluorescent Antibody Technique, Direct ,Medical Microbiology ,Viral Pathogens ,Vertebrates ,Viruses ,Costs and Cost Analysis ,Cost analysis ,Pathogens ,Public aspects of medicine ,RA1-1270 ,Research Article ,Neglected Tropical Diseases ,Veterinary Medicine ,Meat ,Rabies ,Financial feasibility ,030231 tropical medicine ,Nigeria ,Research and Analysis Methods ,Rabies lyssavirus ,Sensitivity and Specificity ,Microbiology ,03 medical and health sciences ,Dogs ,Environmental health ,Animals ,Humans ,Molecular Biology Techniques ,Microbial Pathogens ,Molecular Biology ,Lyssavirus ,Direct fluorescent antibody ,Nutrition ,Diagnostic Tests, Routine ,business.industry ,Organisms ,Public Health, Environmental and Occupational Health ,Biology and Life Sciences ,Tropical Diseases ,biology.organism_classification ,medicine.disease ,Diet ,030104 developmental biology ,Rabies virus ,Food ,Amniotes ,People and Places ,Africa ,Veterinary Science ,business ,Limited resources - Abstract
Background Rabies lyssavirus (RABV) is the aetiologic agent of rabies, a disease that is severely underreported in Nigeria as well as elsewhere in Africa and Asia. Despite the role that rabies diagnosis plays towards elucidating the true burden of the disease, Nigeria–a country of 180 million inhabitants–has a limited number of diagnostic facilities. In this study, we sought to investigate two of the World Organization for Animal Health (OIE)-recommended diagnostic assays for rabies–viz; the direct fluorescent antibody test (DFA) and the direct rapid immunohistochemical test (dRIT) in terms of their relative suitability in resource-limited settings. Our primary considerations were (1) the financial feasibility for implementation and (2) the diagnostic efficacy. As a case study, we used suspect rabies samples from dog meat markets in Nigeria. Methods/Principal findings By developing a simple simulation framework, we suggested that the assay with the lowest cost to implement and routinely use was the dRIT assay. The costs associated with the dRIT were lower in all simulated scenarios, irrespective of the number of samples tested per year. In addition to the cost analysis, the diagnostic efficacies of the two assays were evaluated. To do this, a cohort of DFA-positive and -negative samples collected from dog meat markets in Nigeria were initially diagnosed using the DFA in Nigeria and subsequently sent to South Africa for diagnostic confirmation. In South Africa, all the specimens were re-tested with the DFA, the dRIT and a quantitative real-time polymerase chain reaction (qRT-PCR). In our investigation, discrepancies were observed between the three diagnostic assays; with the incongruent results being resolved by means of confirmatory testing using the heminested reverse transcription polymerase reaction and sequencing to confirm that they were not contamination. Conclusions/Significance The data obtained from this study suggested that the dRIT was not only an effective diagnostic assay that could be used to routinely diagnose rabies, but that the assay was also the most cost-effective option among all of the OIE recommended methods. In addition, the results of our investigation confirmed that some of the dogs slaughtered in dog markets were rabies-positive and that the markets posed a potential public health threat. Lastly, our data showed that the DFA, although regarded as the gold standard test for rabies, has some limitations—particularly at low antigen levels. Based on the results reported here and the current challenges faced in Nigeria, we believe that the dRIT assay would be the most suitable laboratory test for decentralized or confirmatory rabies diagnosis in Nigeria, given its relative speed, accuracy, cost and ease of use., Author summary The under-reporting of rabies in Nigeria may partly be attributed to a lack of adequate diagnostic facilities, which in turn leads to its neglect. The role that dog meat markets play in the epidemiology of rabies in Nigeria remains poorly defined as the activities in these markets are neither properly regulated nor reported to appropriate veterinary and public health authorities. Several diagnostic assays have recently been recommended for rabies diagnosis by the OIE. However, challenges faced in resource-limited countries like Nigeria make the use of some of the recommended assays challenging or impractical. During this study, we evaluated the most feasible OIE-recommended diagnostic assay (based on both diagnostic efficacy and cost) for decentralized laboratory diagnosis of rabies in Nigeria using dog meat markets as a case study. Our findings suggest that the dRIT is best suited for implementation in Nigeria. In addition, our results highlight the importance of confirmatory testing at a central veterinary laboratory, ensuring accurate diagnosis to facilitate improved surveillance for the progression of Nigeria towards eliminating dog rabies.
- Published
- 2020
27. Assessment of some traditional cardiovascular risk factors in medical doctors in Southern Nigeria
- Author
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Tamaraemumoemi Emmanuella Ambakederemo and Eze U. Chikezie
- Subjects
cardiovascular risk factors ,Male ,Health Status ,Endocrinology, Diabetes and Metabolism ,medical doctors ,030204 cardiovascular system & hematology ,Overweight ,Tertiary Care Centers ,0302 clinical medicine ,Health facility ,Risk Factors ,Prevalence ,Pharmacology (medical) ,030212 general & internal medicine ,Original Research ,Hematology ,General Medicine ,Middle Aged ,Cardiovascular Diseases ,Hypertension ,Female ,Diet, Healthy ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,Adult ,Nigeria ,Prehypertension ,Young Adult ,03 medical and health sciences ,Physicians ,Environmental health ,medicine ,Humans ,Aerobic exercise ,Obesity ,Risk factor ,Exercise ,Life Style ,Occupational Health ,lifestyle choices ,business.industry ,Public Health, Environmental and Occupational Health ,Anthropometry ,medicine.disease ,Health Surveys ,Vascular Health and Risk Management ,Cross-Sectional Studies ,Blood pressure ,Fruit ,Fast Foods ,Sedentary Behavior ,business - Abstract
Tamaraemumoemi Emmanuella Ambakederemo,1 Eze Uzoechi Chikezie2 1Department of Internal Medicine, Niger Delta University Teaching Hospital, Okolobiri, Bayelsa, Nigeria; 2Department of Mental Health, Niger Delta University Teaching Hospital, Okolobiri, Bayelsa, Nigeria Introduction: Almost one third of deaths globally are caused by cardiovascular diseases (CVDs). Certain occupations may promote the development and worsening of risk factor for CVDs. We assessed some traditional cardiovascular risk factors and lifestyle choices that may predispose to CVDs in medical doctors in a tertiary health facility in Southern Nigeria. Study design: Cross-sectional study Participants and methods: One hundred sixty-nine apparently healthy medical doctors were recruited. A structured self-administered questionnaire was used to gather data on CVD risk factors. Anthropometric and blood pressure (BP) measurements were taken. Results: Majority were males (68.0%), aged 20–39 years (43.8%), single (62.7%), and house officers (58.0%) with
- Published
- 2018
28. Investigation of 2019 measles outbreak in Yobe state, North-East Nigeria
- Author
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Eze, U., primary, Adewuyi, O., additional, and Abubakar, M., additional
- Published
- 2020
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29. Prevalence and Determinants of Depression among Caregivers of Children with Heart Diseases in Nigeria
- Author
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Chikezie, Eze U., primary, Duru, Chika O., primary, and Okpokowuruk, Frances S., primary
- Published
- 2020
- Full Text
- View/download PDF
30. Economic and feasibility comparison of the dRIT and DFA for decentralized rabies diagnosis in resource-limited settings: The use of Nigerian dog meat markets as a case study
- Author
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Ukamaka, Eze U., primary, Coetzer, Andre, additional, Scott, Terence P., additional, Anene, Boniface M., additional, Ezeokonkwo, Romanus C., additional, Nwosuh, Chika I., additional, Nel, Louis H., additional, and Sabeta, Claude T., additional
- Published
- 2020
- Full Text
- View/download PDF
31. Analytical Prediction of Reservoir Fluids from Rock Physics Models: A Case Study of 'X'- Field Offshore Niger Delta.
- Author
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Ekom, Essien E., Stanley, Eze U., and Saleh, Saleh A.
- Subjects
- *
HYDROCARBON reservoirs , *POISSON'S ratio , *PHYSICS , *GAS condensate reservoirs , *MINERAL properties , *ROCK properties , *ELASTICITY - Abstract
The significance of rock physics analysis in litho-fluid discrimination within a hydrocarbon reservoir using elastic rock properties can never be overstressed in reservoir characterization and hydrocarbon production. The aim of this study is to predict reservoir fluids within a hydrocarbon reservoir using elastic rock properties estimated from well log data from "X-Field" offshore Niger Delta. The reservoir intervals were identified from X-002 as HD1000 and HD2000 at depths of 5740-5780 ft and 5795-5935 ft respectively, which corresponds to the time gate 1345.00-1355.00 ms and 1355-1385 ms respectively on the seismic data. Elastic rock properties estimated within the reservoir window includes P-impedance (Ip), Vp/Vs ratio (velocity ratio), Poisson's ratio (σ), Lambda rho (λρ) and Mu rho (µρ). Cross plot indicators for these properties were colour coded with density and resistivity to give a 3D picture of the attribute response. The cluster pattern on the crossplot space gives a qualitative measure of the discriminative capacity of the attributes under consideration. Cross plot of P-impedance against λρ clearly delineated two zones, indicative of hydrocarbon sands and brine sands. Hydrocarbon zone (HC Sand) was identified by its low values on both Acoustic Impedance and λρ axis. Theoretically, hydrocarbon sands are characterized by low density and high resistivity values, while brine sands are characterized by high density and low resistivity values. Cross plot of µρ versus λρ, showed little or no separation of the reservoir fluids on the µρ axis, as low value of the attribute predominates. However, there is good separation in the λρ axis, making it a more fluid-sensitive attribute. Hydrocarbon zone delineated in this crossplot is suggestive of a gas filled zone based on density and resistivity values on the colour codes, as gas sand facies show lower values of λρ and higher values of µρ. All other attributes cross plots gave seemingly cluster pattern expected for hydrocarbon sands and brine sands at depths of 5758-5791 ft for brine sands, and 5904-5920 ft for hydrocarbon sands judging from the depth colour code in density versus λρ cross plot. These observations are possible because each lithology responds differently to rock properties, depending on the rock fluid content and mineral properties. The results obtained shows that for detailed lithofluid prediction during hydrocarbon exploration and production, it is absolutely necessary to characterize the hydrocarbon reservoir using cross plot indicators with heightened fluid sensitivity. [ABSTRACT FROM AUTHOR]
- Published
- 2021
32. Factors That Contribute to Research and Publication Output Among Librarians in Nigerian University Libraries
- Author
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Eze U. Jacintha and Ijeoma J. Ibegbulam
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education.field_of_study ,business.industry ,020209 energy ,media_common.quotation_subject ,Professional development ,Population ,Attendance ,Library science ,Sample (statistics) ,02 engineering and technology ,Library and Information Sciences ,Education ,Nonprobability sampling ,Promotion (rank) ,Political science ,0202 electrical engineering, electronic engineering, information engineering ,business ,education ,Productivity ,Publication ,media_common - Abstract
Considering the relevance of research and publication in the career and professional development and growth of academic librarians especially in Nigerian Universities, this paper was used to find out the factors which contribute to high publication output among librarians in Nigerian University libraries. The main objectives of the study were to find out librarians' motivation for research and publication; find out the factors that contribute to high research productivity among librarians; find out the barriers to research and publication among librarians; and determine the strategies that will enhance research and publication among librarians. The population of the study comprised of 146 librarians of the university libraries in South-East Nigeria. Purposive sampling based on the level of publication output was used to select about 85 librarians as the sample of the study. The data were collected using a questionnaire and analyzed using frequency counts and mean scores and presented in tables. Major findings showed that the desire to earn promotion and to develop one's self among others motivated the librarians to write and publish while collaboration and attendance to conferences among other factors contributed to high publication output. Lack of a research grant and a tight work schedule hinder research and publication while partnering with research funders and issuance of grants enhanced the opportunities for research and publication.
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- 2016
33. PDG100 PARENTERAL PREPARATIONS STEWARDSHIP IN A TEACHING HOSPITAL IN NIGERIA
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Ogbonna, B.O., primary, Amagba, C., additional, Obiorah, P., additional, Ezenagu, C., additional, Onwuchuluba, E., additional, Eze, U., additional, and Okoli, C., additional
- Published
- 2019
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34. PMU33 ASSESSING NIGERIAN PHARMACISTS' FAMILIARITY AND EDUCATIONAL NEEDS REGARDING DISASTER EMERGENCY PREPAREDNESS COMPETENCIES
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Eze, U., primary, Femi-Oyewo, M.N., additional, and O, O., additional
- Published
- 2019
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35. Isolation and characterization of a bacterial thermostable Protease from poultry dung
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Eze, U N, Okonji, R E, Ibraheem, O, and Shonukan, O O
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Poultry dungs, Bacteria, Thermostable protease, Thermophiles, Klebsiella species - Abstract
Thermophilic bacteria identified as Klebsiella species was isolated from poultry dung using nutrient broth inoculated with pure colonies. The species were grown between temperatures of 45oC to 65oC and was found to be most thermotolerant at 62oC. Protease enzyme was isolated from Klebsiella species and was further purified and characterized through ammonium sulphate precipitation and gel filtration on Sephadex G-100 column chromatography. The specific activity obtained for the partially purified enzyme was 0.1 units/mg protein with 4.2 % protein recovery. The apparent molecular weight as estimated by gel filtration on Sephadex G-100 column was 21.5kDa. The enzyme has optimum activity at pH 9.0 and at temperature of 35 C. An apparent k for the m hydrolysis of casein was found to be approximately 0.75 mg/ml with 0.6 % (w/v) casein.Key words: Poultry dungs, Bacteria, Thermostable protease, Thermophiles, Klebsiella species
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- 2016
36. Mycotoxin exposure and adverse reproductive health outcomes in Africa: a review.
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Eze, U. A., Routledge, M. N., Okonofua, F. E., Huntriss, J., and Gong, Y. Y.
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- 2018
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37. Diminazene aceturate residues in tissues of dogs treated with secnidazole-diminazene aceturate combination and with diminazene aceturate alone.
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Eke, I. G., Eze, U. U., Ezeudu, T. A., Ezeh, I. O., Anaga, A. O., and Onyeyili, P. A.
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DIMINAZENE aceturate ,TISSUES ,DOGS ,MYOCARDIUM ,SKELETAL muscle - Abstract
Dimninazene aceturate concentration in plasma and residues in tissues of dogs treated with secnidazolediminazene aceturate combination and with diminazene aceturate alone was investigated in apparently healthy dogs. Fourteen apparently healthy dogs were randomly assigned to 3 groups. The first group consisted of 6 dogs pre-treated with 100 mg/kg secnidazole (SEC) orally 30 min before administration of 3.5 mg/kg diminazene aceturate (DA) im. The second group consisted of 6 dogs treated with 3.5 mg/kg DA im alone, while the third group had 2 dogs untreated and used to prepare the control tissues and standards. Blood samples were collected at 24, 48 and 72 h post-administration of DA and serum harvested for estimation of DA concentrations in the serum. For estimation of DA residues in tissues, 2 dogs were sacrificed in each group at 240, 360 and 480 h post-administration of the drugs. Ten grams of tissue samples (liver, kidney, brain, heart and skeletal muscle) were collected in triplicate. Intramuscular administration of DA, led to detectable and measurable levels of DA up to 72 h in the serum of both groups of dogs. However, there was no significant difference in the serum concentration of DA in both groups of dogs from 24-72 h. The concentration of DA was significantly (p < 0.05) higher in the brain of SEC pre-treated dogs at 240 h. In the kidney and liver, DA concentration was significantly (p < 0.05) higher in SEC pre-treated dogs at 480 h. There was no significant difference in the DA concentration in the myocardium and skeletal muscles of both groups of dogs. We therefore concluded that DA persists in the tissues of treated dogs beyond 20 days post-treatment and that SEC alters the elimination pattern of DA in SEC pre-treated dogs. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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38. BACTERIAL CONTAMINATION OF DOOR HANDLES/KNOBS IN SELECTED PUBLIC CONVENIENCES IN ABUJA METROPOLIS, NIGERIA: A PUBLIC HEALTH THREAT
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Nworie .A, Ayeni .J. A, Eze .U., A., and Azi .S., O.
- Subjects
parasitic diseases - Abstract
The increasing incidence of epidemic outbreaks of certain diseases and its rate of spread from one community to the other has become a major public health concern. Door handles/knobs of public conveniences of selected public offices, motor parks, and markets in Abuja metropolis were investigated for bacteria contamination. Out of the 180 swab samples cultured, 156 (86.7%) were positive. They were more positive samples from female toilet handles/knobs (41.7%) and bathroom door handles/knobs (11.5%) than males. The study also found that toilet door handles/knobs in markets, motor parks and restaurants had higher rate of contamination compared to Government offices, and banks. Contamination was also higher in toilet door handles/knobs (87.2%) than in bathroom door handles/knobs (85%). Most of the bacteria contaminants were Coliforms. The isolated bacterial contaminants were Staphylococcus aureus (30.1%), Klebsiella Pneumoniae (25.7%), Escherichia coli (16 community health superintendents, sanitary officers and Environmental Protection Board as well as private organizations to educate the populace on personal and environmental hygiene. 1%), Enterobacter species (11.2%), Citrobacter species (7.1%), Pseudomonas aeruginosa (5.9%), and Proteus Species (4.5%). This shows that the city’s convenient places habours highly pathogenic bacteria which have the potentials of causing epidemics in the near future. Therefore, community health superintendents, sanitary officers and Environmental Protection Board as well as private organizations should educate the populace on personal and environmental hygiene. 
- Published
- 2012
- Full Text
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39. PREVALENCE AND AETIOLOGIC AGENTS OF URINARY TRACT INFECTION IN PREGNANCY IN ABAKALIKI METROPOLIS
- Author
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Nworie A and Eze U. A
- Abstract
Urinary tract infections are common in pregnancy and are associated with complications such as abortion, prematurity, low birth weight, stillbirth, maternal anemia, preterm labour, hypertension, thrombosis, phlebitis, pre-eclampsia, chronic pyelonephritis, and rarely, kidney failure. A total of two hundred (200) urine samples were randomly collected from pregnant women attending the antenatal clinics of Ebonyi State University Teaching Hospital and Mile 4 Hospital, both in Abakaliki Metropolis to determine the prevalence of urinary tract infections in pregnancy, aetiologic agents and assess some predisposing factors. Using > 105 colony forming unit per milliliter as significant level of bacteriuria, the prevalence was found to be 48. 0%. There was no significant difference between age and rate of infection (P> 0.05). There was a high incidence in 21 – 25 age group (41.7%). There was also high incidence of infection in the third trimester (82.3%) while the second trimester was (17.7%). Multiparty is associated with increased urinary tract infection in pregnancy. Staphylococcus aureus was the most frequently isolated pathogen (44.8%), followed by Klebsiella pneumonia (15.2%), Escherichia coli (10.5%), Enterococus faecalis (9.5%), Coagulase – Negative Staphylococci (8.6%). Pseudomonas aeruginosa (6.7%), Streptococcus pyogenes and Candida spp. (1.9%) each, and Proteus mirabilis (0.9%). These findings underscore the importance of screening all pregnant women for significant bacteriuria so that positive cases should be treated subsequently with antibiotics in order to reduce the adverse effects on both maternal and fetal health.  
- Published
- 2010
- Full Text
- View/download PDF
40. Correlation of intraoperative cytological and final histological diagnoses: A retrospective 10-year study of neurosurgical cases from Ibadan, Nigeria
- Author
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Salami, A., primary, Azeez, A., additional, Malomo, A., additional, Oluwasola, A., additional, Adeleye, A., additional, Ogun, G., additional, Adeoye, A., additional, Adeolu, A., additional, Okolo, C., additional, Eze, U., additional, Abdullahi, Y., additional, Lawan, A., additional, Ogunbiyi, J., additional, Akang, E., additional, and Shokunbi, M., additional
- Published
- 2014
- Full Text
- View/download PDF
41. Photonic crystal fiber based sensor
- Author
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Ademgil, H., primary, Eze, U. F., additional, Akowuah, E. K., additional, and Haxha, S., additional
- Published
- 2013
- Full Text
- View/download PDF
42. Pattern of gunshot deaths in a Nigerian Tertiary Health Institution.
- Author
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Eze, U. O., Akang, E. E. U., and Odesanmi, W. O.
- Abstract
The present study was aimed to determine the pattern of injuries, manner of death, and demographic parameters of gunshot deaths in a Nigerian teaching hospital. This was a prospective descriptive autopsy study of gunshot deaths seen in the University College Hospital (UCH), Ibadan, over a period of twelve months from January to December 2006. All the coroner autopsies for the period involving gunshot deaths were reviewed with emphasis on the sex, age, occupation, circumstances surrounding the event, manner of death, likely motive in cases of homicidal or suicidal gunshot, type of gun used and site(s) of injury. Gunshot deaths formed eleven (1.6%) of the 697 coroner cases performed at UCH in 2006. Ten of the 11 cases were male, and the overall age range was 10-60 years. The manner of death in ten of such cases was homicide, and unascertained in one case. Rifled weapons were used in 64% of the cases and shotguns, illegally acquired, accounted for the remaining 36%. Most were victims of armed robbery attacks. The head, abdomen, chest and lower limbs were sites of injuries in descending order of frequency. Gunshot deaths were the commonest form of homicide in the period under review. Young males and victims of armed robbery attacks are most susceptible. It is important to note the absence of suicidal gunshot deaths in this study. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
43. Barriers in total productive maintenance implementation in a semiconductor manufacturing firm: A case study
- Author
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Ng, K. C., primary, Goh, G. G. G., additional, and Eze, U. C., additional
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- 2012
- Full Text
- View/download PDF
44. Total productive maintenance in a semiconductor manufacturing firm: an empirical analysis
- Author
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Ng, K. C., primary, Goh, G. G. G., additional, and Eze, U. C., additional
- Published
- 2011
- Full Text
- View/download PDF
45. Critical success factors of total productive maintenance implementation: A review
- Author
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Ng, K. C., primary, Goh, G. G. G., additional, and Eze, U. C., additional
- Published
- 2011
- Full Text
- View/download PDF
46. Pattern of homicide coroner's autopsies at University College Hospital, Ibadan, Nigeria: 1997–2006
- Author
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Eze, U O, primary, Akang, E E U, additional, and Odesanmi, W O, additional
- Published
- 2011
- Full Text
- View/download PDF
47. The influence of total quality management, concurrent engineering and knowledge management in a semiconductor manufacturing firm
- Author
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Ng, P. K., primary, Goh, G. G. G., additional, and Eze, U. C., additional
- Published
- 2010
- Full Text
- View/download PDF
48. Knowledge sharing and Total Quality Management: A conceptual framework
- Author
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Chua, J. L. Y., primary, Eze, U. C., additional, and Goh, G. G. G., additional
- Published
- 2010
- Full Text
- View/download PDF
49. Trends of Polypharmacy Among Elderly Patients Attending An out Patient Clinic.
- Author
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Eze, U, primary and Babalola, M, additional
- Published
- 2010
- Full Text
- View/download PDF
50. Total productive maintenance in a semiconductor manufacturing firm: an empirical analysis.
- Author
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Ng, K. C., Goh, G. G. G., and Eze, U. C.
- Published
- 2011
- Full Text
- View/download PDF
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