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27 results on '"Ewing, Nadia"'

1. A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A

Author

Peyvandi, Flora, Mannucci, Pier M., Garagiola, Isabella, El-Beshlawy, Amal, Elalfy, Mohsen, Ramanan, Vijay, Eshghi, Peyman, Hanagavadi, Suresh, Varadarajan, Ramabadran, Karimi, Mehran, Manglani, Mamta V., Ross, Cecil, Young, Guy, Seth, Tulika, Apte, Shashikant, Nayak, Dinesh M., Santagostino, Elena, Mancuso, Maria Elisa, Sandoval Gonzalez, Adriana C., Mahlangu, Johnny N., Boix, Santiago Bonanad, Cerqueira, Monica, Ewing, Nadia P., Male, Christoph, Owaidah, Tarek, Arellano, Veronica Soto, Kobrinsky, Nathan L., Majumdar, Suvankar, Garrido, Rosario Perez, Sachdeva, Anupam, Simpson, Mindy, Thomas, Mathew, Zanon, Ezio, Antmen, Bulent, Kavakli, Kaan, Manco-Johnson, Marilyn J., Martinez, Monica, Marzouka, Esperanza, Mazzucconi, Maria G., Neme, Daniela, Bravo, Angeles Palomo, Aguilera, Rogelio Paredes, Prezotti, Alessandra, Schmitt, Klaus, Wicklund, Brian M., Zulfikar, Bulent, and Rosendaal, Frits R.

Published
2016
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5. Prediction of Anti-FVIII Inhibitor Persistence By Anti-FVIII IgG Subclasses in Patients with Severe Hemophilia — A in the Sippet Cohort Study

Author

Peyvandi, Flora, primary, Bucciarelli, Paolo, additional, Valsecchi, Carla, additional, Boscarino, Marco, additional, Palla, Roberta, additional, Santagostino, Elena, additional, El-Beshlawy, Amal, additional, Elalfy, Mohsen Saleh, additional, Ramanan, Vijay M., additional, Eshghi, Peyman, additional, Hanagavadi, Suresh, additional, Karimi, Mehran, additional, Ross, Cecil, additional, Manglani, Mamta V, additional, Young, Guy, additional, Seth, Tulika, additional, Apte, Shashikant, additional, Nayak, Dinesh M, additional, Mancuso, Maria Elisa, additional, Mahlangu, Johnny, additional, Santiago, Bonanad, additional, Cerqueira, Monica H, additional, Ewing, Nadia P, additional, Male, Christoph, additional, Owaidah, Tarek, additional, Soto Arellano, Veronica, additional, Majumdar, Suvankar, additional, Simpson, Mindy, additional, Thomas, Mathew, additional, Zanon, Ezio, additional, Manco-Johnson, Marilyn J, additional, Martinez, Monica, additional, Mazzucconi, Maria Gabriella, additional, Neme, Daniela, additional, Paredes-Aguilera, Rogelio Alejandro, additional, Prezotti, Alessandra N L, additional, Schmitt, Klaus, additional, Zulfikar, Bulent, additional, Mannucci, Pier Mannuccio, additional, and Rosendaal, Frits Richard, additional

Published
2018
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7. Source of Factor VIII Replacement (PLASMATIC OR RECOMBINANT) and Incidence of Inhibitory Alloantibodies in Previously Untreated Patients with Severe Hemophilia a: The Multicenter Randomized Sippet Study

Author

Peyvandi, Flora, primary, Mannucci, Pier Mannuccio, additional, Garagiola, Isabella, additional, Elalfy, Mohsen, additional, El-Beshlawy, Amal, additional, Ramanan, Madatha V., additional, Eshghi, Peyman, additional, Hanagavadi, Suresh, additional, Varadarajan, Ramabadran, additional, Karimi, Mehran, additional, Manglani, Mamta V., additional, Ross, Cecil, additional, Young, Guy, additional, Seth, Tulika, additional, Apte, Shashikant, additional, Nayak, Dinesh M., additional, Sandoval Gonzales, Adriana C., additional, Santagostino, Elena, additional, Mancuso, Maria Elisa, additional, Mahlangu, Johnny N., additional, Bonanad, Santiago, additional, Cerqueira, Monica, additional, Ewing, Nadia P., additional, Male, Christoph, additional, Owaidah, Tarek, additional, Soto Arellano, Veronica, additional, Kobrinsky, Nathan L., additional, Majumdar, Suvankar, additional, Perez Garrido, Rosario, additional, Sachdeva, Anupam, additional, Simpson, Mindy, additional, Thomas, Mathew, additional, Zanon, Ezio, additional, Antmen, ALI Bulent, additional, Kavakli, Kaan, additional, Manco-Johnson, Marilyn, additional, Martinez, Monica, additional, Marzouka, Esperanza, additional, Mazzucconi, Maria Gabriella, additional, Neme, Daniela, additional, Palomo Bravo, Angeles, additional, Paredes Aguilera, Rogelio, additional, Prezotti, Alessandra Nunes Loureiro, additional, Klaus, Schmitt, additional, Wicklund, Brian M., additional, Zulfikar, Bulent, additional, and Frits, Rosendaal R., additional

Published
2015
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8. Identifying Nonresponsive Bleeding Episodes in Patients With Haemophilia and Inhibitors: A Consensus Definition

Author

Berntorp, Erik, Collins, Peter, D'Oiron, Roseline, Ewing, Nadia, Gringeri, Alessandro, Negrier, Claude, Department of Coagulation Disorders, Department of Medicine, University Hospital of Wales, Arthur Bloom Haemophilia Centre, Hematology, 3Centre de Traitement pour Hémophiles, AP-HP Hôpital Bicêtre, Université Paris XI, Division of Pediatrics, City of Hope National Medical Center, Department of Internal Medicine, University of Milan, Hôpital Edouard Herriot-Pavillon E, and Ctr. Reg. Traitement Hemophille

Subjects
Medicine
Abstract

International audience; Introduction: Assessing response to treatment with bypassing agents presents a substantial challenge in the treatment of patients with haemophilia and inhibitors. Rapid and accurate identification of bleeding episodes that are nonresponsive to bypassing therapy with either Factor Eight Inhibitor Bypassing Activity (FEIBA; Baxter AG, Vienna, Austria) or recombinant activated factor VII (rFVIIa; NovoSeven®, Novo Nordisk A/S, Bagsvaerd, Denmark) is essential to guide treatment decisions and optimise patient outcomes through early intervention. Although both bypassing agents are effective, differential responses to therapy necessitate multiple therapeutic options. Aim: This paper provides a consensus definition for non-life-threatening joint and muscle bleeds that are nonresponsive to bypassing agents. Methods: An international panel of 7 physicians met in December 2008 to develop the consensus definition using a modified National Institutes of Health Consensus Development Conference method. Results: The consequent definition of non-life-threatening bleeding episodes that are nonresponsive to bypassing treatment provides a global picture of the condition of the patient during such an event. Identification of nonresponsiveness is based on various criteria: pain, swelling/tension, mobility, patient perception, and laboratory parameters. Criteria can be assessed subjectively by the patient/parent, and/or objectively by the clinician. Although the precise timing of each determination should be at the discretion of the physician, bleeds should be considered nonresponsive if the clinical situation meets the specified criteria 24 hours from the start of treatment. Conclusion: Although it is not intended to replace clinical judgment, this definition can guide the optimal course of treatment for patients with haemophilia and inhibitors.

Published
2010
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13. International Consortium for the Study of Clinical and Molecular Aspects of Bernard-Soulier Syndrome

Author

Savoia, Anna, primary, Kunishima, Shinji, additional, Noris, Patrizia, additional, Pujol-Moix, Nuria, additional, Kenny, Dermot, additional, Rosenberg, Nurit, additional, Rand, Margaret L., additional, Zieger, Barbara, additional, Gargouri, Ali F., additional, Beltrame, Miriam P, additional, Molinas, Felisa C., additional, Karimi, Mehran, additional, Ward, Christopher, additional, Kuriakose, Philip, additional, Ewing, Nadia, additional, Diamond, Carol, additional, Srivastava, Alok, additional, Balduini, Carlo Luigi, additional, and Lanza, Francois, additional

Published
2011
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14. A Phase II Open-Label Study Evaluating Hemostatic Activity, Pharmacokinetics and Safety of Recombinant Porcine Factor VIII (OBI-1) in Hemophilia A Patients with Alloantibody Inhibitors Directed Against Human FVIII.

Author

Mahlangu, Johnny, primary, Andreeva, Tatiana A., additional, Macfarlane, Donald, additional, Reding, Mark T., additional, Walsh, Christopher, additional, Ritchie, Bruce, additional, Ewing, Nadia, additional, Kessler, Craig M., additional, Kempton, Christine, additional, Libby, Edward, additional, Zozulya, Nadezda, additional, Shapiro, Amy D., additional, St-Louis, Jean, additional, Warrier, Indira, additional, Hoots, W. Keith, additional, Gruppo, Ralph A., additional, and Mueksch, Josef N., additional

Published
2007
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15. Therapeutic choices for patients with hemophilia and high-titer inhibitors

Author

Kulkarni, Roshni, primary, Aledort, Louis M., additional, Berntorp, Erik, additional, Brackman, Hans H., additional, Brown, Deborah, additional, Cohen, Alan R., additional, Ewing, Nadia P., additional, Gringeri, Alessandro, additional, Gruppo, Ralph, additional, Hoots, Keith, additional, Leissenger, Cindy, additional, Peerlinck, Katheliijne, additional, Poon, Man-Chiu, additional, and Wong, Wing-Yen, additional

Published
2002
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16. Therapeutic choices for patients with hemophilia and high‐titer inhibitors

Author

Kulkarni, Roshni, primary, Aledort, Louis M., additional, Berntorp, Erik, additional, Brackman, Hans H., additional, Brown, Deborah, additional, Cohen, Alan R., additional, Ewing, Nadia P., additional, Gringeri, Alessandro, additional, Gruppo, Ralph, additional, Hoots, Keith, additional, Leissenger, Cindy, additional, Peerlinck, Katheliijne, additional, Poon, Man‐Chiu, additional, and Wong, Wing‐Yen, additional

Published
2001
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20. Hematologic Management of Hemophilia A for Surgery

Author

Kasper, Carol K., Boylen, A. Lois, Ewing, Nadia P., Luck, James V., and Dietrich, Shelby L.

Abstract

From mid-1967 to mid-1983, three hundred fifty surgical operations were performed on 163 patients with hemophilia A, without factor VIII inhibitor. One death occurred, in a patient with a serious head injury. Postoperative hemorrhages occurred after 23% of operations, but the incidence after surgery on the knee, 40%, was decidedly higher than the 15% incidence after operations at other sites. Concurrent plasma factor VIII levels were over 0.40 units/mL in 72% of instances and under 0.30 units/mL in only 15% of instances. The incidence of postoperative hemorrhage did not change over the study period despite a threefold increase in typical dosage of factor VIII (from 600 to 2,000 units/kg per operation) and doubling of typical trough factor VIII levels (from 0.37 units/mL to 0.70 units/mL). Circulating factor VIII levels apparently are not the sole determinants of postoperative bleeding in hemophilia A.(JAMA 1985;253:1279-1283)

Published
1985
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21. Newborn Diagnosis of Abnormal Hemoglobins from a Large Municipal Hospital in Los Angeles.

Author

Ewing, Nadia, Powars, Darleen, Hilburn, Jean, and Schroeder, Walter A.

Subjects
*HEMOGLOBINOPATHY, *SICKLE cell anemia, *NEWBORN infants
Abstract

Cord blood samples from 29,611 infants born in Los Angeles over a 7 1/2 year period were examined for hemoglobinopathies. Among 4,134 Black newborns, the frequency of sickle cell anemia (SS) was 0.3 per cent of sickle cell trait (AS) 8 per cent, and of Hb-C trait (AC) 2 per cent, Of 17,781 Spanish surnamed (Mexican) newborn, 0.5 per cent had sickle cell trait, and 0.1 per cent had Hb-C trait. Of the 5,541 Caucasian infants, 0.7 per cent had sickle cell trait, and 0.15 per cent had Hb-C trait. Twenty-three Black children with major hemoglobinopathies included 16 with sickle cell anemia, two with hemoglobin C disease (CC), and five with SC disease. [ABSTRACT FROM AUTHOR]

Published
1981
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26. Issues Surrounding Genetic Screening Programs.

Author

Ewing, Nadia P.

Subjects
*LETTERS to the editor, *MEDICAL screening
Abstract

A response by Nadia Ewing on a letter to the editor about her article on genetic screening programs in the June 1981 issue of the Journal.

Published
1981

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