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Your search keyword '"Ewe, See H."' showing total 16 results
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16 results on '"Ewe, See H."'

15. Global Longitudinal Strain Predicts Long-Term Survival in Patients With Chronic Ischemic Cardiomyopathy.

Author

Bertini, Matteo, Ng, Arnold C. T., Antoni, M. Louisa, Nucifora, Gaetano, Ewe, See H., Auger, Dominique, Marsan, Nina Ajmone, Schalij, Martin J., Bax, Jeroen J., and Delgado, Victoria

Subjects
PROGNOSIS, LEFT heart ventricle, CARDIAC contraction, CARDIOMYOPATHIES, ECHOCARDIOGRAPHY
Abstract

The article evaluates the prognostic value of left ventricular (LV) global longitudinal strain (GLS) as a new index of LV systolic function in chronic ischemic cardiomyopathy and to determine the incremental value of GLS in predicting long term outcomes in patients. The study involved 1,060 patients who underwent transthoracic echocardiography. Results indicated that LV GLS assessment is significantly related to long term outcomes in ischemic cardiomyopathy patients.

Published
2012
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16. Global longitudinal strain predicts left ventricular dysfunction after mitral valve repair.

Author

Witkowski TG, Thomas JD, Debonnaire PJ, Delgado V, Hoke U, Ewe SH, Versteegh MI, Holman ER, Schalij MJ, Bax JJ, Klautz RJ, and Marsan NA

Subjects
Aged, Algorithms, Cardiac Surgical Procedures adverse effects, Disease Progression, Echocardiography methods, Female, Follow-Up Studies, Heart Valve Prosthesis Implantation methods, Hemodynamics, Humans, Male, Middle Aged, Mitral Valve diagnostic imaging, Mitral Valve surgery, Mitral Valve Insufficiency complications, Mitral Valve Insufficiency physiopathology, Predictive Value of Tests, Prognosis, Prospective Studies, Reproducibility of Results, Sensitivity and Specificity, Severity of Illness Index, Stroke Volume, Ventricular Dysfunction, Left etiology, Mitral Valve Insufficiency diagnostic imaging, Mitral Valve Insufficiency surgery, Ventricular Dysfunction, Left diagnostic imaging, Ventricular Dysfunction, Left surgery
Abstract

Aims: Despite a successful surgical procedure and adherence to current recommendations, postoperative left ventricular (LV) dysfunction after mitral valve repair (MVr) for organic mitral regurgitation (MR) may still occur. New approaches are therefore needed to detect subclinical preoperative LV dysfunction. LV global longitudinal strain (GLS), assessed with speckle-tracking echocardiographic analysis, has been proposed as a novel measure to better depict latent LV dysfunction. The aim of this study was to investigate the value of GLS to predict long-term LV dysfunction after MVr., Methods and Results: A total of 233 patients (61% men, 61 ± 12 years) with moderate-severe organic MR who underwent successful MVr between 2000 and 2009 were included. Echocardiography was performed at baseline and long-term follow-up (34 ± 20 months) after MVr. LV dysfunction at follow-up was defined as LV ejection fraction (EF) <50% and was present in 29 (12%) patients. A cut-off value of -19.9% of GLS showed a sensitivity and specificity of 90 and 79% to predict long-term LV dysfunction. By univariate logistic regression analysis, baseline LVEF ≤60%, LV end-systolic diameter (ESD) ≥40 mm, atrial fibrillation, presence of symptoms, and GLS >-19.9% were predictors of long-term LV dysfunction. By multivariate analysis, GLS remained an independent predictor of LV dysfunction (odds ratio 23.16, 95% confidence interval: 6.53-82.10, P < 0.001), together with LVESD., Conclusion: In a large series of patients operated within the last decade, MVr resulted in a low incidence of long-term LV dysfunction. A GLS of >-19.9% demonstrated to be a major independent predictor of long-term LV dysfunction after adjustment for parameters currently implemented into guidelines.

Published
2013
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