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4 results on '"Eusuff SI"'

1. Tuberculous infection in Saharia, a primitive tribal community of Central India

Author

Rajpal S. Yadav, M.K. Bhondeley, K. Sadacharam, R. Subramani, G.P. Shukla, V. G. Rao, Jyothi Bhat, P G Gopi, Eusuff Si, Vijay Gadge, M. Vasantha, Balkrishna Tiwari, and Anupkumar R. Anvikar

Subjects
Male, medicine.medical_specialty, Tuberculosis, Cross-sectional study, Population, India, Tuberculin, Rural Health, Risk Assessment, Internal medicine, Epidemiology, Prevalence, medicine, Humans, Child, education, Tuberculina, education.field_of_study, biology, Tuberculin Test, business.industry, Public Health, Environmental and Occupational Health, Infant, General Medicine, biology.organism_classification, medicine.disease, Mycobacterium bovis, Surgery, Cross-Sectional Studies, Infectious Diseases, Clinical research, Child, Preschool, Tropical medicine, Female, Parasitology, business
Abstract

A cross-sectional tuberculin survey was carried out to estimate the prevalence of tuberculous infection and the annual risk of tuberculosis infection (ARTI) among children of Saharia, a primitive ethnic group in Madhya Pradesh, Central India. A total of 1341 children aged 1—9 years were subjected to tuberculin testing with 1 TU of PPD RT 23 and the reaction sizes were read after 72 h. The proportion of BCG scar-positive children was 34.6%. The frequency distribution of children by reaction sizes indicated a clear-cut anti-mode at 11mm and a mode at 18mm at the right-hand side of the distribution. The prevalence of infection among children irrespective of BCG scar was estimated as 20.4% (95% CI 18.2—22.5%) and the ARTI was 3.9% (95% CI 3.5—4.3%). The corresponding figures were 21.1% (95% CI 18.3—23.8%) and 3.9% (95% CI 3.4—4.5%) among BCG scar-negative children and 19.0% (95% CI 15.4—22.5%) and 4.0% (95% CI 3.2—4.8%) among BCG scar-positive children. The findings of the present study show a high prevalence of tuberculous infection and high ARTI in this primitive ethnic group. There is an urgent need to further intensify tuberculosis control measures on a sustained and long-term basis in this area.

Published
2008
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2. Status of smear-positive TB patients at 2-3 years after initiation of treatment under a DOTS programme.

Author

Sadacharam K, Gopi PG, Chandrasekaran V, Eusuff SI, Subramani R, Santha T, and Narayanan PR

Subjects
Adult, Aged, Female, Follow-Up Studies, Humans, India, Male, Middle Aged, Risk Factors, Rural Population, Time Factors, Treatment Outcome, Tuberculosis mortality, Directly Observed Therapy, Health Status, Tuberculosis therapy
Abstract

Objective: To describe the status of cases 2-3 years after the initiation of treatment under DOTS., Setting: After DOTS implementation in Tiruvallur district, south India, we followed up a cohort of smear-positive TB patients registered during 2002-03 after initiation of treatment., Results: The overall mortality rate was 15.0% and among the remaining 18.6% had active disease. In multivariate analysis, a higher mortality rate was independently associated with age, sex, occupation, treatment outcome and initial body weight of patients., Conclusion: The mortality and morbidity rates are still high during follow-up and needs to be curtailed by addressing these issues effectively in TB control programme.

Published
2007

3. Predictors of relapse among pulmonary tuberculosis patients treated in a DOTS programme in South India.

Author

Thomas A, Gopi PG, Santha T, Chandrasekaran V, Subramani R, Selvakumar N, Eusuff SI, Sadacharam K, and Narayanan PR

Subjects
Adult, Directly Observed Therapy, Female, Humans, India epidemiology, Male, Middle Aged, Recurrence, Risk Factors, Smoking epidemiology, Smoking Cessation, Tuberculosis, Pulmonary drug therapy, Tuberculosis, Pulmonary epidemiology
Abstract

Objective: To identify risk factors associated with relapse among cured tuberculosis (TB) patients in a DOTS programme in South India., Design: Sputum samples collected from a cohort of TB patients registered between April 2000 and December 2001 were examined by fluorescence microscopy for acid-fast bacilli and by culture for Mycobacterium tuberculosis at 6, 12 and 18 months after treatment completion., Results: Of the 534 cured patients, 503 (94%) were followed up for 18 months after treatment completion. Of these, 62 (12%) relapsed during the 18-month period; 48 (77%) of the 62 relapses occurred during the first 6 months of follow-up. Patients who took treatment irregularly were twice more likely to have a relapse than adherent patients (20% vs. 9%; adjusted odds ratio [aOR] 2.5; 95% CI 1.4-4.6). Other independent predictors of relapse were initial drug resistance to isoniazid and/or rifampicin (aOR 4.8; 95% CI 2.0-11.6) and smoking (aOR 3.1; 95% CI 1.6-6.0). The relapse rate among non-smoking, treatment adherent patients with drug-sensitive organisms was 4.8%., Conclusions: The relapse rate under the DOTS programme may be reduced by ensuring that patients take their treatment regularly and are counselled effectively about quitting smoking.

Published
2005

4. Smear examination of two specimens for diagnosis of pulmonary tuberculosis in Tiruvallur District, south India.

Author

Gopi PG, Subramani R, Selvakumar N, Santha T, Eusuff SI, and Narayanan PR

Subjects
Humans, India, Microscopy, Retrospective Studies, Sensitivity and Specificity, Specimen Handling, Time Factors, Sputum cytology, Tuberculosis, Pulmonary diagnosis
Abstract

Settings: A general hospital and three peripheral health institutions (PHI) in Tiruvallur District, south India., Objective: To validate the case detection strategy for diagnosis of pulmonary tuberculosis by smear microscopy of two sputum specimens versus three., Methods: In the Revised National Tuberculosis Control Programme (RNTCP), three smears from every symptomatic patient attending the PHI were examined for acid-fast bacilli (AFB) by Ziehl-Neelsen (ZN) microscopy. The data from the Tuberculosis Laboratory Registers from the above centres were analysed., Results: Of 7843 chest symptomatics who had provided three sputum specimens for examination, 895 (11.4%) were smear-positive on at least two specimens. Examination of two specimens--first spot and early morning specimens (837, 93.5%) or early morning and second spot specimens (843, 94.2%)--yielded the highest number of cases., Conclusion: The examination of two sputum smears (one spot and an early morning) is as effective as examination of three smears.

Published
2004

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