9 results on '"Eurenius, Lars"'
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2. Risk Factors and Markers for Acute Myocardial Infarction With Angiographically Normal Coronary Arteries
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Daniel, Maria, Ekenbäck, Christina, Agewall, Stefan, Brolin, Elin B., Caidahl, Kenneth, Cederlund, Kerstin, Collste, Olov, Eurenius, Lars, Frick, Mats, Younis-Hassan, Shams, Henareh, Loghman, Jernberg, Tomas, Malmqvist, Karin, Spaak, Jonas, Sörensson, Peder, Hofman-Bang, Claes, and Tornvall, Per
- Published
- 2015
- Full Text
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3. Clinical Frailty Scale classes are independently associated with 6-month mortality for patients after acute myocardial infarction
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Ekerstad, Niklas, Javadzadeh, Dariush, Alexander, Karen P., Bergström, Olle, Eurenius, Lars, Fredrikson, Mats, Gudnadottir, Gudny, Held, Claes, Ängerud, Karin Hellström, Jahjah, Radwan, Jernberg, Tomas, Mattsson, Ewa, Melander, Kjell, Mellbin, Linda, Ohlsson, Monica, Ravn-Fischer, Annica, Svennberg, Lars, Yndigegn, Troels, Alfredsson, Joakim, Ekerstad, Niklas, Javadzadeh, Dariush, Alexander, Karen P., Bergström, Olle, Eurenius, Lars, Fredrikson, Mats, Gudnadottir, Gudny, Held, Claes, Ängerud, Karin Hellström, Jahjah, Radwan, Jernberg, Tomas, Mattsson, Ewa, Melander, Kjell, Mellbin, Linda, Ohlsson, Monica, Ravn-Fischer, Annica, Svennberg, Lars, Yndigegn, Troels, and Alfredsson, Joakim
- Abstract
Aims Data on the prognostic value of frailty to guide clinical decision-making for patients with myocardial infarction (MI) are scarce. To analyse the association between frailty classification, treatment patterns, in-hospital outcomes, and 6-month mortality in a large population of patients with MI. Methods and results An observational, multicentre study with a retrospective analysis of prospectively collected data using the SWEDEHEART registry. In total, 3381 MI patients with a level of frailty assessed using the Clinical Frailty Scale (CFS-9) were included. Of these patients, 2509 (74.2%) were classified as non-vulnerable non-frail (CFS 1-3), 446 (13.2%) were vulnerable non-frail (CFS 4), and 426 (12.6%) were frail (CFS 5-9). Frailty and non-frail vulnerability were associated with worse in-hospital outcomes compared with non-frailty, i.e. higher rates of mortality (13.4% vs. 4.0% vs. 1.8%), cardiogenic shock (4.7% vs. 2.5% vs. 1.9%), and major bleeding (4.5% vs. 2.7% vs. 1.1%) (all P < 0.001), and less frequent use of evidence-based therapies. In Cox regression analyses, frailty was strongly and independently associated with 6-month mortality compared with non-frailty, after adjustment for age, sex, the GRACE risk score components, and other potential risk factors [hazard ratio (HR) 3.32, 95% confidence interval (CI) 2.30-4.79]. A similar pattern was seen for vulnerable non-frail patients (fully adjusted HR 2.07, 95% CI 1.41-3.02). Conclusion Frailty assessed with the CFS was independently and strongly associated with all-cause 6-month mortality, also after comprehensive adjustment for baseline differences in other risk factors. Similarly, non-frail vulnerability was independently associated with higher mortality compared with those with preserved functional ability.
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- 2022
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4. Clinical Frailty Scale classes are independently associated with 6-month mortality for patients after acute myocardial infarction
- Author
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Ekerstad, Niklas, primary, Javadzadeh, Dariush, additional, Alexander, Karen P, additional, Bergström, Olle, additional, Eurenius, Lars, additional, Fredrikson, Mats, additional, Gudnadottir, Gudny, additional, Held, Claes, additional, Ängerud, Karin Hellström, additional, Jahjah, Radwan, additional, Jernberg, Tomas, additional, Mattsson, Ewa, additional, Melander, Kjell, additional, Mellbin, Linda, additional, Ohlsson, Monica, additional, Ravn-Fischer, Annica, additional, Svennberg, Lars, additional, Yndigegn, Troels, additional, and Alfredsson, Joakim, additional
- Published
- 2021
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5. Clinical Frailty Scale classes are independently associated with 6-month mortality for patients after acute myocardial infarction
- Author
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Ekerstad, Niklas, Javadzadeh, Dariush, Alexander, Karen P, Bergström, Olle, Eurenius, Lars, Fredrikson, Mats, Gudnadottir, Gudny, Held, Claes, Ängerud, Karin Hellström, Jahjah, Radwan, Jernberg, Tomas, Mattsson, Ewa, Melander, Kjell, Mellbin, Linda, Ohlsson, Monica, Ravn-Fischer, Annica, Svennberg, Lars, Yndigegn, Troels, Alfredsson, Joakim, Ekerstad, Niklas, Javadzadeh, Dariush, Alexander, Karen P, Bergström, Olle, Eurenius, Lars, Fredrikson, Mats, Gudnadottir, Gudny, Held, Claes, Ängerud, Karin Hellström, Jahjah, Radwan, Jernberg, Tomas, Mattsson, Ewa, Melander, Kjell, Mellbin, Linda, Ohlsson, Monica, Ravn-Fischer, Annica, Svennberg, Lars, Yndigegn, Troels, and Alfredsson, Joakim
- Abstract
Aims: Data on the prognostic value of frailty to guide clinical decision-making for patients with myocardial infarction (MI) are scarce. To analyse the association between frailty classification, treatment patterns, in-hospital outcomes, and 6-month mortality in a large population of patients with MI. Methods and Results: An observational, multicentre study with a retrospective analysis of prospectively collected data using the SWEDEHEART registry. In total, 3381 MI patients with a level of frailty assessed using the Clinical Frailty Scale (CFS-9) were included. Of these patients, 2509 (74.2%) were classified as non-vulnerable non-frail (CFS 1-3), 446 (13.2%) were vulnerable non-frail (CFS 4), and 426 (12.6%) were frail (CFS 5-9). Frailty and non-frail vulnerability were associated with worse in-hospital outcomes compared with non-frailty, i.e. higher rates of mortality (13.4% vs. 4.0% vs. 1.8%), cardiogenic shock (4.7% vs. 2.5% vs. 1.9%), and major bleeding (4.5% vs. 2.7% vs. 1.1%) (all P < 0.001), and less frequent use of evidence-based therapies. In Cox regression analyses, frailty was strongly and independently associated with 6-month mortality compared with non-frailty, after adjustment for age, sex, the GRACE risk score components, and other potential risk factors [hazard ratio (HR) 3.32, 95% confidence interval (CI) 2.30-4.79]. A similar pattern was seen for vulnerable non-frail patients (fully adjusted HR 2.07, 95% CI 1.41-3.02). Conclusion: Frailty assessed with the CFS was independently and strongly associated with all-cause 6-month mortality, also after comprehensive adjustment for baseline differences in other risk factors. Similarly, non-frail vulnerability was independently associated with higher mortality compared with those with preserved functional ability.
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- 2021
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6. Clinical Frailty Scale classes are independently associated with 6-month mortality for patients after acutemyocardial infarction.
- Author
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Ekerstad, Niklas, Javadzadeh, Dariush, Alexander, Karen P., Bergström, Olle, Eurenius, Lars, Fredrikson, Mats, Gudnadottir, Gudny, Held, Claes, Hellström Ängerud, Karin, Jahjah, Radwan, Jernberg, Tomas, Mattsson, Ewa, Melander, Kjell, Mellbin, Linda, Ohlsson, Monica, Ravn-Fischer, Annica, Svennberg, Lars, Yndigegn, Troels, and Alfredsson, Joakim
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- 2022
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7. Cross-professional improvement actions to reduce time from first ECG to primary PCI in patients with ST-elevation myocardial infarction
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Eurenius, Lars, primary, Cedergren, Ewa, additional, Östlund-Papadogeorgos, Nikolaos, additional, and Persson, Jonas, additional
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- 2016
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8. Annual report SWEDEHEART 2012
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Wahlberg, Anna-Maria, primary, Alenström, Magdalena, additional, Udin, Stina, additional, Johansson, Tore, additional, Lundgren, Anna, additional, Romany Johansson, Birgitta, additional, Ekström, Carin, additional, Eriksson, Nils, additional, Andersson, Lisbeth, additional, Eklund, Hanna, additional, Robertsson, Lotta, additional, Bjerhag, Gunilla, additional, Gustavsson, Ann-Charlotte, additional, Israelsson, Madelene, additional, Karlsson, Sofia, additional, Westerlund, Maria, additional, Ek, Yvonne, additional, Stenbäck, Birgitta, additional, Andersson, Barbro, additional, Andersson, Elisabeth, additional, Leppämäki, Kristina, additional, Ramirez, Anette, additional, Wallin, Victoria, additional, Lundberg, Alexandra, additional, Sahlin, Benny, additional, Mälberg, Hasse, additional, Liljeroos, Maria, additional, Gustafsson, Caroline, additional, Nyström, Kerstin, additional, Siklo, Susanne, additional, Zelleroth, Eva, additional, Hjortevang, Finn, additional, Mohammed, Kamaran, additional, Hellblad, Agneta, additional, Schön, Iwona, additional, Carlsson, Kristina, additional, Ole´rs, Marita, additional, Ågren, Pär Lennart, additional, Sjögren, Iwar, additional, Zedigh, Crister, additional, Eriksson, Kristina, additional, Sundkvist, Kristina, additional, Thorsell, Anna-Karin, additional, Kuoljok, Ann-Kristin, additional, Liinanki, Linda, additional, Liljergren, Mona, additional, Turtola, Sara, additional, Nylander, Britt-Marie, additional, Nordvall, Lena, additional, Nilsson, Malin, additional, Blomqvist, Annelie, additional, Sjöberg, Håkan, additional, Nylander, Jenny, additional, Berglund, Linda, additional, Mossberg, Linda, additional, Svennberg, Lars, additional, Haugen, Espen, additional, Hellsten, Lars, additional, Johansson, Staffan, additional, Johansson, Birgitta, additional, Larsson, Pethra, additional, Kellerth, Susanne, additional, Bergström, Monika, additional, Gustafsson, Carola, additional, Nährström, Cecilia, additional, Evenås, Eva, additional, Sundin, Hanna, additional, Lönn, Helena, additional, Svensson, Johan, additional, Kihlgren, Moa, additional, Larsson, Per, additional, Palosaari, Pirjo, additional, Johansson, Susann, additional, Cedermark magnusson, Malin, additional, Ravn-Fischer, Annica, additional, Wittfeldt, Ann, additional, Perers, Elisabeth, additional, Hellberg, Nina, additional, Holmberg, Mikael, additional, Andersson, Bert, additional, Jangsten, Berit, additional, Selimovic, Nedim, additional, Enström, Anna, additional, Dellgren, Göran, additional, Scherstén, Henrik, additional, Biveby-Nilsson, Anna, additional, Lundberg, Johan, additional, Omerovic, Elmir, additional, Petursson, Petur, additional, Albertsson, Per, additional, Ankarstrand, Carina, additional, Flinck, Agneta, additional, Larsson, Titti, additional, Samuelsson, Maria, additional, Bergman, Peter, additional, Nyström, Lotten, additional, Bågenholm, Magnus, additional, Linnér, Anneli, additional, Hornestam, Björn, additional, Sjöland, Helén, additional, Kirkhoff, Anne-Marie, additional, Månsson, Hugo, additional, Karlsson, Ida, additional, Olausson, Maria, additional, Berne, Charlotte, additional, Backe, Christina, additional, Tabandeh, Ali, additional, Karlsson, Ann-Charlotte, additional, Hårdhammar, Peter, additional, Olsson, Sven-Erik, additional, Persson, Henrik, additional, Wagner, Ole, additional, Wagner, Henrik, additional, Sandhall, Lennart, additional, Wåhlander, Carina, additional, Rova, Kristina, additional, Fischer, Lina, additional, Nilsson, Maria, additional, Stjernberg, Mari, additional, Gustavsson, Sylvia, additional, Hedberg, Camilla, additional, Thollander, Jan, additional, Collberg, Katarina, additional, Lauermann, Jörg, additional, Puskar, Werner, additional, Larsson, Margareta, additional, Johansson, Ann, additional, Brindstedt, Lina, additional, Olofsson, Marina, additional, Carlsson, Jörg, additional, Månsson, Katarina, additional, Jeppsson, Ulla, additional, Söderlind, Ingbritt, additional, Hultman, Malinn, additional, Ronnelin, Sara, additional, Fredriksson, Carina, additional, Skogman, Gerd, additional, Ågren, Ingela, additional, Almroth, Inger, additional, Trege Nilsson, Sara, additional, Pettersson, Gerd, additional, Åkesson, Ing-Marie, additional, Carlfelter, Sofia, additional, Medin, Jan, additional, Mokhtar, Karim, additional, Pripp, Carl-Magnus, additional, Malmsten, Linda, additional, Karlsson, Annelie, additional, Lenberg, Anna, additional, Lettenström, Annika, additional, Jost-Widén, Anna, additional, Johnson, Gunilla, additional, Ahlmark, Håkan, additional, Brevik, Hannah, additional, Nordberg, IngaLill, additional, Österberg-Persson, Jessica, additional, Smedberg, Jeanette, additional, Eklund, Maria, additional, Haaga, Urban, additional, Henriksson, Anne-Marie, additional, Allared, Mats, additional, Olsson, Hans, additional, Nilsson, Tage, additional, Juhlin, Lisa, additional, Eriksson, Karin, additional, Hedquist, Leif, additional, Lundin, Ulla, additional, Jonsson, Christin, additional, Pedersen, Monica, additional, Marainen, Julia, additional, Bylund, Moa, additional, Alsterdal, Monica, additional, Sjöberg, Anna, additional, Wigenstorp, Ewa, additional, Peterzen, Gunilla, additional, Skeppstedt, Kerstin, additional, Berlin, Anette, additional, Wikström, Helena, additional, Pihl, Kerstin, additional, Ferm, Lehna, additional, Larsson, Petra, additional, Johansson, Vanja, additional, Finnas, Gunvor, additional, Ahlm, Helen, additional, Ekelind, Anders, additional, Larsson, Eva, additional, Eriksson, Gull-Britt, additional, Sass, Veronica, additional, Johansson, Åsa, additional, Malmqvist, Lennart, additional, Westin, Lars, additional, Sigurjonsdottir, Eydis, additional, Skuladottir, Frida, additional, Ottesen, Maria, additional, Bjarnadottir, Olga Birgitta, additional, Myrdal, Gunnar, additional, Traustadottir, Edda, additional, Sigvaldadóttir, Friðrika, additional, Garðarsdóttir, Gerður, additional, Valgeirsdottir, Gudrun, additional, Magnusdottir, Sigurlaug, additional, Bjornsdottir, Thora, additional, Gudnason, Thorarinn, additional, Matthiasdottir, Svava, additional, Jonsson, Maria, additional, Pettersson, Ulrika, additional, Peterson, Magnus, additional, Molander, Karin, additional, Larsson, Micael, additional, Samuelsson, Berit, additional, Svensson, Catarina, additional, Augustsson, Elisabeth, additional, BertilssonFröjd, Evelin, additional, Alfredsson, Joakim, additional, Freter, Wolfgang, additional, Lilja, Linda, additional, Andersson, Gunnel, additional, Venetsanos, Dimitrios, additional, Björkholm, Anders, additional, Tödt, Tim, additional, Berglund, Ulf, additional, Nielsen, Niels Erik, additional, Johansson, Jenny, additional, Svensson, Johanna, additional, Larsson, Rosie-Marie, additional, Lundmark, Liselotte, additional, Brolin, Gunilla, additional, Westergren, Annika, additional, Duckert, Anna, additional, Steffan, Vesna, additional, Götberg, Matthias, additional, Erlinge, David, additional, Scherstén, Fredrik, additional, Olivecrona, Göran, additional, Harnek, Jan, additional, Bondesson, Per, additional, Knutsson, Pernilla, additional, Stenlund, Evy, additional, Thorén, Peter, additional, Algotsson, Siv, additional, Durakovic, Enisa, additional, Gustafsson, Lisa, additional, Nilsson, Marie, additional, Nilson, Margareta, additional, Bhiladvala, Pallonji, additional, Håkansson, Monica, additional, Svensson, Carina, additional, Olsson, Ingela, additional, Kjellstenius, Amelie, additional, Åslund, Jenny, additional, Alledal, Linnéa, additional, Varblane, Nina, additional, Nilsson, Victoria, additional, Thudén, Maria, additional, Jensen, Siv-Britt, additional, Svensson, Elisabet, additional, Pettersson, Maria, additional, Lindgren, Sanna, additional, Pehrsson, Anita, additional, Olsson, Maria, additional, Rudenäs, Anneli, additional, Öhman, Eva, additional, Falk, Stig-Åke, additional, Jaensson, Annelie, additional, Thell, Lena, additional, Billqvist, Annette, additional, Efraimsson-Nilsson, Barbro, additional, Allansson, Ingalill, additional, Jansson, Malin, additional, Ingström, Ann, additional, Lundqvist, Christina, additional, Nyström, Ingela, additional, Bergman, Ingrid, additional, Ekman, Johan, additional, Carlson, Lena, additional, Person, Solveig, additional, Lindberg, Ingrid, additional, Thuesen, Leif, additional, Lindberg, Erik, additional, Lundberg, Gunnilla, additional, Hedberg, Kerstin, additional, Kotka, Inga-Lill, additional, Fogelberg, Anja, additional, Johansson, Anna, additional, Ståhl, Lis, additional, Kallryd, Anders, additional, Ramén, Agneta, additional, Löfmark, Henrik, additional, Fessahaie, Senait, additional, Brandrup-Wognsen, Malin, additional, Salomonsson, Claire, additional, Ardin, Petra, additional, Balcker, Eva, additional, Högberg, Filippa, additional, Högberg, Fredrik, additional, Hultin Ånnegård, Eva, additional, Svensson, Marcus, additional, Tornestedt, Marie, additional, Björkander, Inge, additional, Edström, Cathrine, additional, Eurenius, Lars, additional, Samnegård, Ann, additional, Persson, Jonas, additional, Östlund Papadogeorgos, Nikolaos, additional, Mir-Akbari, Habib, additional, Stengård, Görel, additional, Bacsovics Brolin, Elin, additional, Brehmer, Katarina, additional, Osman, Fauzia, additional, Törnblom, Marie, additional, Sundkvist, Katja, additional, Kumhala, Caroline, additional, Jonsson, Ellinor, additional, Yazar, Alexandra, additional, Siddiqui, Anwar, additional, Rück, Andreas, additional, Henareh, Loghman, additional, Cederlund, Kerstin, additional, Lemberg, Ewa, additional, Larsson, Elin, additional, Persson, Amanda, additional, Andersson, Karolin, additional, Svensson, Per, additional, A - Moalim, Fauzia, additional, Lundgren, Ann, additional, Gustavsson-segerhag, Ellen, additional, Nordvall, Agneta, additional, Söderlund, Gunnel, additional, Jarnert, Christina, additional, Mellbin, Linda, additional, Ivert, Torbjörn, additional, Linder, Rikard, additional, Törnerud, Mattias, additional, Edén, Birgit, additional, Lockne, Kristina, additional, Rennerskog, Sebastian, additional, Kosmack, Jan, additional, Erlandsson, Marianne, additional, Lindroos, Pontus, additional, Peltonen, Armi, additional, Creutziger, Christine, additional, Berglund, Ellinor, additional, Henriksson, Marie, additional, Ingeborn, Carina, additional, Collste, Olov, additional, Aasa, Mikael, additional, Karlsson, Karin, additional, Andersson, Ulla, additional, Kohlström Englund, Lis, additional, Henning, Mia, additional, Vinblad v Walter, Anna-Greta, additional, Nilsson, Christina, additional, Schilken, Helena, additional, Johansson, Inger, additional, Wallgren, Ingrid, additional, Niemi, Kristina, additional, Niva, Oili, additional, Dofs, Margareta, additional, Johansson, Agneta, additional, Haupt, Jan, additional, Näslund, Christina, additional, Drewsen, Henrik, additional, Söderlund, Maria, additional, Berts, Birgitta, additional, Lindvall, Bo, additional, Wadell, Daniel, additional, Jensen, Jens, additional, Hedh, Åsa, additional, Johnson, Karin, additional, Nikitin, Cecilia, additional, Eriksson, Eva-Lena, additional, Westlund, Elisabeth, additional, Karlsson, Inger, additional, Björkdahl, Peter, additional, Uher, Radim, additional, Nyman, Ulf, additional, Yndigegn, Troels, additional, Broberg, Anette, additional, Lamreus, Linda, additional, Söderström, Alexandra, additional, Lång, Marianne, additional, Olsson, Henrik, additional, Hussien Al-Saadi, Madhat, additional, Landén, Emma, additional, Holmgren, Maria, additional, Rivera San Martin, Tomas, additional, Nyström, Karin, additional, Wahlin, Magnus, additional, Angerås, Oskar, additional, Nilsson, Johan, additional, Eriksson, Peter, additional, Sundberg, Anna, additional, Sandström, Inger, additional, Duvernoy, Olov, additional, Andreasson, Maria, additional, Ekström, Johanna, additional, Essermark, Marie, additional, Wall, Helena, additional, Marklund, Elisabeth, additional, Östlund, Cecilia, additional, Willehadson, Maria, additional, Björklund, Christina, additional, Dimberg, Axel, additional, Zemgulis, Vitas, additional, Olsson, Agneta, additional, Hagström, Susanne, additional, Bergman, Carina, additional, Gunnarsson, Annika, additional, Huhta, My, additional, Svensson, Christina, additional, Hultman, Per, additional, Varenhorst, Christoph, additional, Kvidal, Per, additional, Stener Bengtsson, Annika, additional, Wännman, Ann-Lis, additional, Nilsson, Lisbeth, additional, Andersson, Tomas, additional, Josefsson, Maritha, additional, Morén, Maria, additional, Hultman-Berg, Lena, additional, Almqwist, Anna-Karin, additional, Cederblad, Monica, additional, Ekberg, Katarina, additional, Kvarnvik, Gunilla, additional, Jönsson, Eston, additional, Hammerman, Annelie, additional, Claesson, Pia, additional, Widerström, Gith, additional, Pettersson Olsson, Sandra, additional, Hofvander, Åsa, additional, Lindholm, Martin, additional, Saidi, Saman, additional, Grimfjärd, Per, additional, Kåregren, Amra, additional, Runesson, Madeleine, additional, Josefsson, Anders, additional, Henriksson-Fri, Lena, additional, Johansson, Miriam, additional, Gustavsson, Solgärd, additional, Markljung, Minna, additional, Bergström, Olle, additional, Aronsson, Thomas, additional, Karlsson, Ewa, additional, Boström, Pernilla, additional, Hansson, Sofia, additional, Andreasson, Inger, additional, Palmqvist, Lena, additional, Kähäri, Anders, additional, Lidén, Mats, additional, Oskarsson, Frida, additional, Östman, Ingela, additional, Kronberg, Johanna, additional, Johansson, Marie, additional, Thuresson, Marie, additional, Geijer, Håkan, additional, Fröbert, Ole, additional, Kellerth, Thomas, additional, Tillkvist, Maud, additional, Ajax, Kirsti, additional, Björklund, Fredrik, additional, and Björklund, Anna, additional
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- 2014
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9. Clinical Frailty Scale classes are independently associated with 6-month mortality for patients after acute myocardial infarction.
- Author
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Ekerstad N, Javadzadeh D, Alexander KP, Bergström O, Eurenius L, Fredrikson M, Gudnadottir G, Held C, Ängerud KH, Jahjah R, Jernberg T, Mattsson E, Melander K, Mellbin L, Ohlsson M, Ravn-Fischer A, Svennberg L, Yndigegn T, and Alfredsson J
- Subjects
- Aged, Frail Elderly, Humans, Prognosis, Prospective Studies, Retrospective Studies, Frailty, Myocardial Infarction
- Abstract
Aims: Data on the prognostic value of frailty to guide clinical decision-making for patients with myocardial infarction (MI) are scarce. To analyse the association between frailty classification, treatment patterns, in-hospital outcomes, and 6-month mortality in a large population of patients with MI., Methods and Results: An observational, multicentre study with a retrospective analysis of prospectively collected data using the SWEDEHEART registry. In total, 3381 MI patients with a level of frailty assessed using the Clinical Frailty Scale (CFS-9) were included. Of these patients, 2509 (74.2%) were classified as non-vulnerable non-frail (CFS 1-3), 446 (13.2%) were vulnerable non-frail (CFS 4), and 426 (12.6%) were frail (CFS 5-9). Frailty and non-frail vulnerability were associated with worse in-hospital outcomes compared with non-frailty, i.e. higher rates of mortality (13.4% vs. 4.0% vs. 1.8%), cardiogenic shock (4.7% vs. 2.5% vs. 1.9%), and major bleeding (4.5% vs. 2.7% vs. 1.1%) (all P < 0.001), and less frequent use of evidence-based therapies. In Cox regression analyses, frailty was strongly and independently associated with 6-month mortality compared with non-frailty, after adjustment for age, sex, the GRACE risk score components, and other potential risk factors [hazard ratio (HR) 3.32, 95% confidence interval (CI) 2.30-4.79]. A similar pattern was seen for vulnerable non-frail patients (fully adjusted HR 2.07, 95% CI 1.41-3.02)., Conclusion: Frailty assessed with the CFS was independently and strongly associated with all-cause 6-month mortality, also after comprehensive adjustment for baseline differences in other risk factors. Similarly, non-frail vulnerability was independently associated with higher mortality compared with those with preserved functional ability., (© The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.)
- Published
- 2022
- Full Text
- View/download PDF
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