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786 results on '"Ettinger M"'

8. Network dynamics predict improvement in working memory performance following donepezil administration in healthy young adults

Author

Reches, A, Laufer, I, Ziv, K, Cukierman, G, McEvoy, K, Ettinger, M, Knight, RT, Gazzaley, A, and Geva, AB

Subjects
Biomedical and Clinical Sciences, Mental Health, Acquired Cognitive Impairment, Clinical Research, Neurodegenerative, Neurosciences, Behavioral and Social Science, Brain Disorders, Dementia, Basic Behavioral and Social Science, 1.2 Psychological and socioeconomic processes, 6.1 Pharmaceuticals, Underpinning research, Evaluation of treatments and therapeutic interventions, Neurological, Mental health, Adult, Brain Mapping, Brain Waves, Cholinesterase Inhibitors, Donepezil, Evoked Potentials, Female, Humans, Indans, Male, Memory, Short-Term, Mental Recall, Pattern Recognition, Visual, Performance-Enhancing Substances, Piperidines, Young Adult, BNA, Working memory, Cognitive enhancement, EEG, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery, Biomedical and clinical sciences, Health sciences
Abstract

Attentional selection in the context of goal-directed behavior involves top-down modulation to enhance the contrast between relevant and irrelevant stimuli via enhancement and suppression of sensory cortical activity. Acetylcholine (ACh) is believed to be involved mechanistically in such attention processes. The objective of the current study was to examine the effects of donepezil, a cholinesterase inhibitor that increases synaptic levels of ACh, on the relationship between performance and network dynamics during a visual working memory (WM) task involving relevant and irrelevant stimuli. Electroencephalogram (EEG) activity was recorded in 14 healthy young adults while they performed a selective face/scene working memory task. Each participant received either placebo or donepezil (5mg, orally) on two different visits in a double-blinded study. To investigate the effects of donepezil on brain network dynamics we utilized a novel EEG-based Brain Network Activation (BNA) analysis method that isolates location-time-frequency interrelations among event-related potential (ERP) peaks and extracts condition-specific networks. The activation level of the network modulated by donepezil, reflected in terms of the degree of its dynamical organization, was positively correlated with WM performance. Further analyses revealed that the frontal-posterior theta-alpha sub-network comprised the critical regions whose activation level correlated with beneficial effects on cognitive performance. These results indicate that condition-specific EEG network analysis could potentially serve to predict beneficial effects of therapeutic treatment in working memory.

Published
2014

26. A pilot study: Image-less robotic-assisted revision arthroplasty shows comparable surgery time, alignment accuracy, bone preserving and early revision rate compared to robotic-assisted primary TKA

Author

Tuecking, LR, Savov, P, Windhagen, H, and Ettinger, M

Subjects
surgery time, ddc: 610, accuracy, robotic assisted revision TKA, Medicine and health, Robot assisted TKA, alignment
Abstract

Objectives: The number of revision arthroplasty operations is rising recently. Robotic arthroplasty is increasingly being used in primary arthroplasty and is already showing promising results in terms of accuracy and revision rates. The purpose of this pilot study is to investigate the operation time, [for full text, please go to the a.m. URL]

Published
2021
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27. Die Anwendung roboterassistierter Verfahren senkt überdurchschnittliche Versorgungskosten für die Implantation primärer Knie-Totalendoprothesen in komplexen Fällen

Author

Stauß, R, Savov, P, Tücking, LR, Windhagen, H, and Ettinger, M

Subjects
total knee arthroplasty, episode of care costs, ddc: 610, TKA, Medicine and health, case complexity, complex knee, readmission rate
Abstract

Fragestellung: Ökonomische Studien zeigten überhöhte Versorgungskosten (90-day Episode of Care Costs, EOC) für die Implantation primärer Knie-Totalendoprothesen (KTEP) in einem Patientenkollektiv mit größerer Fallkomplexität. Der Einfluss roboterassistierter Verfahren [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2021
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49. Wieviel Mehraufwand bedeuten computergestützte Operationsverfahren zur Knie TEP Implantation? Eine multizentrische Analyse von 5 aktuellen Technologien

Author

Calliess, T, Tanner, L, Ettinger, M, and Christen, B

Subjects
ddc: 610, Kosten, Kniepxrothetik, PSI, 610 Medical sciences, Medicine, Navigation, Robotic
Abstract

Fragestellung: In den vergangenen Jahren sind zahlreiche neue Technologien zur Verbesserung der Präzision bei Knie-TEPs vorgestellt worden. Trotz des Nachweises einer erhöhten Genauigkeit stehen diese Therapien weiterhin in der Kritik, da bis heute der klinische Nutzen nicht eindeutig bewiesen[zum vollständigen Text gelangen Sie über die oben angegebene URL], Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2019)

Published
2019
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