25 results on '"Estrade, G."'
Search Results
2. Developing an integrated petrogenetic model for understanding REE deportment of the Ampasibitika Intrusion and associated ion adsorption deposits
- Author
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Marquis, E., Goodenough, K.M., Smith, M.P., Estrade, G., Rasolonirina, F., Rakotoson, R.L., Marquis, E., Goodenough, K.M., Smith, M.P., Estrade, G., Rasolonirina, F., and Rakotoson, R.L.
- Abstract
Alkaline–peralkaline igneous systems are promising sources of rare earth elements (REEs). Preservation bias has resulted in a gap in the geological record for alkaline–peralkaline magmatic systems, with the hypabyssal plumbing system linking magma chambers to extrusive volcanic rocks poorly represented. Large plutonic varieties of these systems are often proposed to have fed (now eroded) volcanoes, and current peralkaline volcanic systems obscure the plutonic system at depth. The alkaline to peralkaline Ampasibitika Intrusion in Madagascar is a rare example where the magmatic–volcanic interface between a deeper level magma reservoir and its genetically related caldera volcano is exposed. This c. 24 Ma sub-volcanic intrusive system comprises silica-undersaturated to silica-oversaturated units, of peralkaline to metaluminous and peraluminous characters, with varying styles of REE mineralisation, including supergene ion adsorption-style REE occurrences in the overlying weather profiles. There are two main intrusive suites: (1) the concentric Marginal Dyke Swarm (MDS) formed of quartz–microsyenite and peralkaline granite dykes (PGDs), and (2) the Ampasibitika Ring Dyke (ARD) comprising alkali feldspar syenites and subordinate nepheline syenites, trachytes and phonolites. We present new field observations and geochemical data to indicate that the MDS was emplaced as a series of low-viscosity, volatile-rich melt batches, which coalesced in the magma reservoir roof zone and intruded prior to caldera collapse, whereas the ARD was emplaced into the ring fault as a heterogeneous mix of variably evolved syenitic crystal mushes and phonolitic to trachytic-melt batches. As such, we suggest the MDS represents the residual melt fraction of the magma reservoir, whereas the ARD contains portions of the fractionating, silica-neutral to silica-undersaturated syenite, cumulate assemblage. In this revised framework, we assess the major and trace element geochemistry of amphibole- and cl
- Published
- 2023
3. Facteurs de risque de l'infarctus du myocarde du sujet jeune : registre prospectif sur un an
- Author
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Joussein-Remacle, S., Delarche, N., Bader, H., Lasserre, R., and Estrade, G.
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- 2006
- Full Text
- View/download PDF
4. Prise en charge préhospitalière de l'infarctus du myocarde à la phase aiguë dans la région sanitaire VI. Évaluation prospective sur l'année 2002
- Author
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Iriart, X., Delarche, N., Auzon, P., Denard, M., and Estrade, G.
- Published
- 2005
- Full Text
- View/download PDF
5. Hyperthyroïdie néonatale sévère, révélatrice d’une maladie de basedow maternelle
- Author
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Guérin, B., Vautier, V., Boin-Gay, V., Estrade, G., Choulot, J.-J., and Doireau, V.
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- 2004
- Full Text
- View/download PDF
6. Dorsalgies révélant une maladie de Takayasu
- Author
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Noyer, B., primary, Guérin, B., additional, Delarche, N., additional, Estrade, G., additional, Monlun, E., additional, and Doireau, V., additional
- Published
- 2004
- Full Text
- View/download PDF
7. From magma reservoir to regolith: controls on the distribution of ion adsorption rare earth element ores.
- Author
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Marquis E., Estrade G., Goodenough K., Smith M., Villanova-de-Benavent C., Marquis E., Estrade G., Goodenough K., Smith M., and Villanova-de-Benavent C.
- Abstract
Ion adsorption deposits are the main source of heavy REE, which include Dy, to global markets. Although low grade, these regolith-hosted REE deposits host over 50% of their REE in an ion exchangeable form, and so the REE can be liberated using in-situ or heap leaching techniques with weak electrolyte solutions The Ambohimirahavavy alkaline to peralkaline complex in Madagascar has undergone extensive tropical weathering that has developed thick regolith profiles hosting ion adsorption ores. Its southern portion comprises a caldera complex, eroded to expose a sub-volcanic nepheline and alkali feldspar syenite ring dyke and marginal concentric dyke swarm of peralkaline granite and microsyenite, which are variably REE-enriched. It is suggested that silica-saturation was triggered by accumulation of volatile-rich melts in the upper portions of the magma reservoir underlying the caldera, which resulted in (re-)melting of previously crystallised cumulates and/or minor assimilation of crustal material. Extraction of these silica-saturated melts during doming, associated with magma reservoir inflation, would account for the concentric outcrop expression of the marginal dyke swarm. Thus, the most REE-enriched protoliths are concentrated on the outer flanks of the AAC’s southern caldera, which correspond with higher-grade ion adsorption ores in the regolith., 6 refs., Ion adsorption deposits are the main source of heavy REE, which include Dy, to global markets. Although low grade, these regolith-hosted REE deposits host over 50% of their REE in an ion exchangeable form, and so the REE can be liberated using in-situ or heap leaching techniques with weak electrolyte solutions The Ambohimirahavavy alkaline to peralkaline complex in Madagascar has undergone extensive tropical weathering that has developed thick regolith profiles hosting ion adsorption ores. Its southern portion comprises a caldera complex, eroded to expose a sub-volcanic nepheline and alkali feldspar syenite ring dyke and marginal concentric dyke swarm of peralkaline granite and microsyenite, which are variably REE-enriched. It is suggested that silica-saturation was triggered by accumulation of volatile-rich melts in the upper portions of the magma reservoir underlying the caldera, which resulted in (re-)melting of previously crystallised cumulates and/or minor assimilation of crustal material. Extraction of these silica-saturated melts during doming, associated with magma reservoir inflation, would account for the concentric outcrop expression of the marginal dyke swarm. Thus, the most REE-enriched protoliths are concentrated on the outer flanks of the AAC’s southern caldera, which correspond with higher-grade ion adsorption ores in the regolith.
8. Late- to post-magmatic alteration of syenitic rocks of the Ambohimirahavavy complex: insights into fluids potentially mobilising REE.
- Author
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Marquis E., Estrade G., Goodenough K., Smith M., Marquis E., Estrade G., Goodenough K., and Smith M.
- Abstract
Although late-magmatic alteration is a consistent feature for the development of HREE-enriched granites in southern China, there has been little investigation into the characteristics of the fluid phases associated with this alteration. Tantalus Rare Earths' prospect in northwest Madagascar is currently unique as it encompasses both peralkaline igneous and regolith deposits, the regolith profiles containing REE having developed upon alkaline to peralkaline igneous and volcanic parent rocks of the Ambohimirahavavy complex. Major intrusive rocks of the complex include alkali feldspar and nepheline syenites, which form the main ring dyke and a marginal dyke swarm comprised of quartz microsyenite and peralkaline granite sheets. Petrographic observations in the ring-dyke syenites indicate that alteration of REE minerals and REE mobilisation occurred at late stages in the magmatic evolution of some of the syenites at Ambohimirahavavy. In some cases, such as within the alkali feldspar syenites, this resulted in the development of REE-fluorcarbonates which are amenable to breakdown during weathering; however, within the nepheline syenites typical late-stage REE-minerals include zirconosilicates and REE-phosphates that are relatively resistant to dissolution at low temperatures. Thus, the late- to post magmatic mineral assemblages have had important implications for the release of REE into the regolith, and hence for the grade of the deposit., Although late-magmatic alteration is a consistent feature for the development of HREE-enriched granites in southern China, there has been little investigation into the characteristics of the fluid phases associated with this alteration. Tantalus Rare Earths' prospect in northwest Madagascar is currently unique as it encompasses both peralkaline igneous and regolith deposits, the regolith profiles containing REE having developed upon alkaline to peralkaline igneous and volcanic parent rocks of the Ambohimirahavavy complex. Major intrusive rocks of the complex include alkali feldspar and nepheline syenites, which form the main ring dyke and a marginal dyke swarm comprised of quartz microsyenite and peralkaline granite sheets. Petrographic observations in the ring-dyke syenites indicate that alteration of REE minerals and REE mobilisation occurred at late stages in the magmatic evolution of some of the syenites at Ambohimirahavavy. In some cases, such as within the alkali feldspar syenites, this resulted in the development of REE-fluorcarbonates which are amenable to breakdown during weathering; however, within the nepheline syenites typical late-stage REE-minerals include zirconosilicates and REE-phosphates that are relatively resistant to dissolution at low temperatures. Thus, the late- to post magmatic mineral assemblages have had important implications for the release of REE into the regolith, and hence for the grade of the deposit.
9. The origin of skarn-hosted rare-metal mineralisation in the Ambohimirahavavy alkaline complex, Madagascar.
- Author
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Estrade G., Beziat D., Salvi S., Williams-Jones A.E., Estrade G., Beziat D., Salvi S., and Williams-Jones A.E.
- Abstract
The Cainozoic Ambohimirahavavy alkaline complex consists of several syenitic to granitic intrusions (24.2 +/- 0.6 Ma) the largest of which, the Ampasibitika intrusion, is characterised by the presence in its outer flanks of late peralkaline granitic dykes intruding mudstone and limestone of the Isalo Group. A network of dykelets and veinlets propagates from these dykes, and at the contact between these and a limestone, a reaction zone enriched in rare metals forms a rare example of skarn resulting from peralkaline igneous activity. Much of the rare-metal mineralisation (REE, Zr, Nb, Th, Sn, and Ti) occurs as secondary phases in the dykelets and endoskarn; high field strength element (HFSE)-rich phases consist mainly of zircon, bastnaesite-(Ce), and Ca-REE-, and Ca-HFSE-rich phases in pseudomorphs after aegirine-augite. In the exoskarn, the main HFSE-rich phases are bastnaesite-(Ce), zircon, pyrochlore, Nb-rich titanite, and an unidentified F-rich Ca-zirconosilicate finely disseminated in a matrix composed of calcite, diopside, andradite, phlogopite, quartz, fluorite, and fluorapatite. The secondary zircon is characterised by a low Zr content and by the presence of REE, Ca, Al, and Fe. Three types of primary fluid inclusions were observed in dykelets and skarn in quartz, calcite, and diopside. A model is proposed in which rare metals were transported by a Cl-, F- and HFSE-rich orthomagmatic fluid exsolved at 400 to 450 degrees C and about 20 MPa. At these conditions, the fluid was in the two-phase region and vapour dominated. The rare metals were deposited as a result of the interaction of this fluid with limestone and mixing with an external fluid., The Cainozoic Ambohimirahavavy alkaline complex consists of several syenitic to granitic intrusions (24.2 +/- 0.6 Ma) the largest of which, the Ampasibitika intrusion, is characterised by the presence in its outer flanks of late peralkaline granitic dykes intruding mudstone and limestone of the Isalo Group. A network of dykelets and veinlets propagates from these dykes, and at the contact between these and a limestone, a reaction zone enriched in rare metals forms a rare example of skarn resulting from peralkaline igneous activity. Much of the rare-metal mineralisation (REE, Zr, Nb, Th, Sn, and Ti) occurs as secondary phases in the dykelets and endoskarn; high field strength element (HFSE)-rich phases consist mainly of zircon, bastnaesite-(Ce), and Ca-REE-, and Ca-HFSE-rich phases in pseudomorphs after aegirine-augite. In the exoskarn, the main HFSE-rich phases are bastnaesite-(Ce), zircon, pyrochlore, Nb-rich titanite, and an unidentified F-rich Ca-zirconosilicate finely disseminated in a matrix composed of calcite, diopside, andradite, phlogopite, quartz, fluorite, and fluorapatite. The secondary zircon is characterised by a low Zr content and by the presence of REE, Ca, Al, and Fe. Three types of primary fluid inclusions were observed in dykelets and skarn in quartz, calcite, and diopside. A model is proposed in which rare metals were transported by a Cl-, F- and HFSE-rich orthomagmatic fluid exsolved at 400 to 450 degrees C and about 20 MPa. At these conditions, the fluid was in the two-phase region and vapour dominated. The rare metals were deposited as a result of the interaction of this fluid with limestone and mixing with an external fluid.
10. Adsorption of rare earth elements in regolith-hosted clay deposits.
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Borst AM, Smith MP, Finch AA, Estrade G, Villanova-de-Benavent C, Nason P, Marquis E, Horsburgh NJ, Goodenough KM, Xu C, Kynický J, and Geraki K
- Abstract
Global resources of heavy Rare Earth Elements (REE) are dominantly sourced from Chinese regolith-hosted ion-adsorption deposits in which the REE are inferred to be weakly adsorbed onto clay minerals. Similar deposits elsewhere might provide alternative supply for these high-tech metals, but the adsorption mechanisms remain unclear and the adsorbed state of REE to clays has never been demonstrated in situ. This study compares the mineralogy and speciation of REE in economic weathering profiles from China to prospective regoliths developed on peralkaline rocks from Madagascar. We use synchrotron X-ray absorption spectroscopy to study the distribution and local bonding environment of Y and Nd, as proxies for heavy and light REE, in the deposits. Our results show that REE are truly adsorbed as easily leachable 8- to 9-coordinated outer-sphere hydrated complexes, dominantly onto kaolinite. Hence, at the atomic level, the Malagasy clays are genuine mineralogical analogues to those currently exploited in China.
- Published
- 2020
- Full Text
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11. Importance of anterograde visualization of the coronary venous network by selective left coronary angiography prior to resynchronization.
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Delarche N, Bader H, Lasserre R, Derval N, Debeugny S, Denard M, and Estrade G
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- Aged, Female, Humans, Male, Coronary Angiography, Coronary Vessels anatomy & histology, Pacemaker, Artificial
- Abstract
Background: Understanding of coronary anatomy is essential to the advancement of cardiac resynchronization therapy (CRT) techniques. We determined whether the difficulties associated with catheterization of the coronary sinus (CS) and its lateral branches could be overcome by a preliminary angiographical study of the coronary venous system carried out during a pre-operative coronary angiography with examination of venous return., Methods and Results: All patients were scheduled for an exploratory angiography procedure and indicated for CRT. Group A patients were implanted with a CRT device after a right arterial angiographical procedure while group B patients had a selective left angiogram including examination of venous return. Data analyzed in group B were: position of CS ostium, number and distribution of lateral branches, and ability to preselect a marginal vein suitable for catheterization. Subsequent device implantation was guided by these parameters. A total of 96 and 89 patients were included in groups A and B, respectively. Implantation success rates were not different (98% and 100%, respectively), but CS catheterization time was reduced in group B (6 minutes vs 4 minutes; P < 10(-6)) as well as total time required to position the left ventricular lead (25 minutes vs 15 minutes; P < 10(-6)), fluoroscopy exposure (7 minutes vs 5 minutes; P < 10(-6)), and volume of contrast medium required (45 mL vs 15 mL; P < 10(-6))., Conclusion: A coronary angiographical study, including examination of the coronary venous return prior to implantation of a CRT device, can simplify the device implant and allows patient-specific preselection of appropriate tools for the procedure.
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- 2007
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12. [Risk factors in a young population with acute myocardial infarction: one year prospective study].
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Joussein-Remacle S, Delarche N, Bader H, Lasserre R, and Estrade G
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- Adult, Age Factors, Cardiovascular Diseases complications, Dyslipidemias complications, Female, Humans, Male, Middle Aged, Myocardial Infarction prevention & control, Prognosis, Prospective Studies, Risk Factors, Smoking adverse effects, Myocardial Infarction epidemiology, Myocardial Infarction etiology
- Abstract
Objective: The objective of this work is to give epidemiological data, established in a prospective way, on the myocardial infarction in young and its risk factors., Methods: All patients admitted to the CHG of Pau for myocardial infarction, old, for the men of less than 45 years and for the women of less than 55 years, of November the 1st 2002 to October 31st, 2003, are included., Results: Twenty-seven patients (11.2%) do a myocardial infarction including 44.4% women. The found traditional risk factors are: smoking (92.6%), absence of regular physical activity (81.5%), dyslipidaemia (66.7%), family history of cardiovascular disease (48.2%), hypertension (37.0%), obesity (18.5%), oral contraception (11.1%), diabetes (7.4%), personal thrombotic history (7.4%). The principal emergent risk factors highlighted are: stress (66.7%), inhibitor of the activation of the plasminogene (57.1%), C-reactive protein (50%), lipoprotein a (41.7%), fibrinogen (33.3%), elevated plasma homocysteine (25%), excessive alcohol use (22.2%). None patients does not have an absolute cardiovascular risk > 20%. The clinical characteristics, coronarographic data and the acute treatments were also listed. The prognosis is worse for the women with more risk factors, more complications, and risk of more significant ventricular replanning., Conclusion: The principal risk factors of the myocardial infarction in young can be modifiable. The prevention is of primary importance. The therapeutic education of the patients corresponds to the total assumption of responsibility required by this pathology.
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- 2006
- Full Text
- View/download PDF
13. [Takayasu disease revealed by dorsalgia].
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Noyer B, Guérin B, Delarche N, Estrade G, Monlun E, and Doireau V
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- Aorta, Thoracic diagnostic imaging, Aortography, Child, Diagnosis, Differential, Humans, Male, Takayasu Arteritis radiotherapy, Takayasu Arteritis diagnosis, Takayasu Arteritis diagnostic imaging
- Abstract
Unlabelled: Takayasu arteritis is an uncommon inflammatory arteritis especially in children. We report a case., Case Report: A 11-year-old boy presented dorsalgia with inflammatory syndrome. One year later, the investigation of an hypertension with asymmetric blood pressure revealed an aortic coarctation and a bilateral renal arteries stenosis leading to Takayasu's arteritis diagnosis., Conclusion: Takayasu's arteritis must be evokated in young children in case of associated hypertension and inflammatory syndrome.
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- 2004
- Full Text
- View/download PDF
14. [Severe neonatal hyperthyroidism which reveals a maternal Graves' disease].
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Guérin B, Vautier V, Boin-Gay V, Estrade G, Choulot JJ, and Doireau V
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- Antithyroid Agents therapeutic use, Carbimazole therapeutic use, Female, Humans, Hyperthyroidism drug therapy, Infant, Newborn, Pregnancy, Graves Disease physiopathology, Hyperthyroidism congenital, Hyperthyroidism etiology, Pregnancy Complications physiopathology
- Abstract
Two of every thousand pregnancies are complicated by Graves' disease. Diagnosis is suggested by maternal disorders (tachycardia, exophthalmia, weight loss.) or fetal disorders (tachycardia, intra-uterine growth retardation, preterm birth.). Due to transfer into the fetal compartment of maternal antibodies which stimulate the fetal thyroid by binding to the thyroid thyrotropin (TSH) receptor, only 1% of children born to these mothers are described as having hyperthyroidism. Neonatal thyrotoxicosis disappears with clearance of the maternal antibodies; clinical signs usually disappear during the first four Months of life. The most frequent neonatal clinical signs of thyrotoxicosis are tachycardia, goiter, hyperexcitability, poor weight gain, hepatosplenomegaly, stare and eyelid retraction. Diagnosis is based on determination of the blood level of triiodothyronine (T3), thyroxine (T4) and TSH. To confirm the nature of hyperthyroidism, thyroid-stimulating immunoglobulins (TSI) should be assayed. The kinetics of TSI provides a guide for therapeutic adaptation and disappearance of TSI is a sign of recovery. Rare cases of familial non-autoimmune hyperthyroidism have been shown to be caused by germline mutation of the thyrotropin receptor. We report a case of severe neonatal hyperthyroidism which led to the diagnosis of maternal Graves' disease.
- Published
- 2004
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15. [Value of eptifibatide during salvage angioplasty with coronary stenting after failure of thrombolysis. Report of a series of 41 patients].
- Author
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Idir M, Delarche N, Banos JL, Milandou A, Ache Papillon C, and Estrade G
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- Adult, Aged, Drug Resistance, Eptifibatide, Female, Humans, Male, Middle Aged, Peptides administration & dosage, Platelet Aggregation Inhibitors administration & dosage, Risk Factors, Salvage Therapy, Stents, Treatment Outcome, Angioplasty, Fibrinolytic Agents therapeutic use, Myocardial Infarction therapy, Peptides pharmacology, Platelet Aggregation Inhibitors pharmacology, Prosthesis Implantation, Recombinant Proteins therapeutic use, Tissue Plasminogen Activator therapeutic use
- Abstract
Aim: To evaluate the risks and the significance of the use of an anti-GPIIb/IIIa, in this case Eptifibatide, during angioplasty following presumed failure of thrombolysis in the acute phase of myocardial infarction., Method: Patients thrombolyzed following MI < 6 hours. Presumed failure of reperfusion with full dose thrombolysis. Analysis evaluated the success of angioplasty associated with anti-GPIIb/IIIa treatment and the hospital phase outcome., Results: 41 consecutive patients, 32 male (78%) and 9 female (22%), were included. Infarction concerned the anterior region in 22 cases (54%) and inferior in 19 cases (46%). Fibrinolysis was performed using Alteplase in 28 patients (68%) and Reteplase in 13 patients (32%). Radial access was performed in 32 cases (78%). All of the patients received Eptifibatide with a bolus then infusion from their admission to the haemodynamic suite, on average 1 h 30 after the start of thrombolytic treatment. A total of 49 stents were implanted in 41 patients. A flux of TIMI 3 was obtained in 37 patients (90.2%). TIMI 2 in 2 patients (4.9%) and no reflow in 2 patients (4.9%). Four counter-pulsions by intra-aortic balloon were necessary (9.8%) for cardiogenic shock. No decrease in TIMI flux was observed after the angioplasty procedure. The main complications were a death from cardiogenic shock in one patients (2.4%), a non-fatal digestive tract haemorrhage in 2 cases (4.9%) and a single femoral haematoma requiring transfusion., Conclusion: The initial results were encouraging: high success rates, rare vascular complications, a probable consequence of the radial approach. The association of an anti-GPIIb/IIIa, Eptifibatide, therefore appears achievable during angioplasty with the positioning of a coronary endoprosthesis following the presumed failure of full dose thrombolysis.
- Published
- 2002
16. Direct Angioplasty for Acute Myocardial Infarction in Elderly Patients Using Transradial Approach.
- Author
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Delarche N, Idir M, Estrade G, and Leblay M
- Abstract
BACKGROUND: In acute myocardial infarction (AMI), immediate outcome seems to be better after direct coronary angioplasty (DCA) than thrombolysis. Right transradial approach (RTRA) has been currently advocated as an alternative catheterization method for coronary angioplasty, but it is an exceptional technique in the treatment of AMI. PURPOSE: The goal of this prospective study was to evaluate feasibility and safety of DCA using the RTRA in elderly patients. METHODS: All patients, 70 years or older with AMI (less than 6 hours after the onset of symptoms), were included in this study. Exclusion criteria were ischemic Allen Test, and previous thrombolytic treatment. Left heart catheterization, with selective coronary angiograms were realized in all of them, using RTRA. RESULTS: Forty six patients, (mean age 76Â+/-5, range 70-85), (31 men, 15 women), were included. Coronary catheterization using RTRA was not possible in 4 patients, (9.1%), and DCA was not necessary in 2 other patients with two distal lesions (4.5%). In the 40 remaining patients, transradial coronary angioplasty of the infarct related vessel could be successfully achieved in 40 patients, (100%) with balloon alone in 21 patients, (52.5%), or stents in 19 patients, (47.5%). Two patients with cardiogenic shock died (in hospital mortality: 4.5%). In 2 patients, recurrent angina needed new angioplasty using the same RTRA (4.5%), and in 2 other patients, asymptomatic postprocedural right radial artery occlusion was observed. Before the 24th hr, 30/40 patients (75%) could stand up with an early discharge, (7Â+/-4 days). CONCLUSION: DCA using RTRA for AMI in elderly patients can be easily realized, with a high rate of success, without any more major local complications than using the usual femoral route, allowing earlier getting up and discharge.
- Published
- 1999
17. [Double aneurysm occurring on a venous aortocoronary graft].
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Zely P, Delarche N, Estrade G, Blay ML, Ledoyer G, and Laborde N
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- Coronary Aneurysm diagnosis, Coronary Aneurysm surgery, Coronary Angiography, Coronary Artery Bypass methods, Follow-Up Studies, Humans, Male, Middle Aged, Radiography, Thoracic, Reoperation, Saphenous Vein transplantation, Tomography, X-Ray Computed, Coronary Aneurysm etiology, Coronary Artery Bypass adverse effects
- Abstract
The authors report the case of a 48-year old patient admitted to hospital for unstable angina 13 years after primary myocardial revascularisation by a saphenous vein aorto-coronary bypass graft. Routine chest X-ray showed a left para-hilar opacity which CT scan and angiography confirmed to be aneurysmal and pseudoaneurysmal dilatations of the saphenous vein bypass graft.
- Published
- 1996
18. [The association of ankylosing spondylitis and Takayasu's disease. 3 new cases].
- Author
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Cherin P, Blétry O, Ziza JM, Kieffer E, Arfi S, Estrade G, and Godeau P
- Subjects
- Adult, Aortic Valve Insufficiency etiology, Female, HLA Antigens analysis, Humans, In Vitro Techniques, Male, Middle Aged, Spondylitis, Ankylosing immunology, Takayasu Arteritis immunology, Aortic Arch Syndromes complications, Spondylitis, Ankylosing complications, Takayasu Arteritis complications
- Published
- 1990
19. [Congenital diverticulum of the right ventricle apropos of a case complicated by pulmonary endocarditis].
- Author
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Garnier D, Estrade G, Bernasconi F, Guilmet D, Glaudon G, and Donatien Y
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- Child, Diverticulum complications, Heart Ventricles, Humans, Male, Diverticulum congenital, Endocarditis etiology, Heart Defects, Congenital etiology, Pulmonary Valve
- Abstract
Congenital diverticulum of the right ventricle is an extremely rare abnormality, usually discovered by chance during evaluation of a more complex cardiac malformation. We report a case of isolated diverticulum of the right ventricle in a 14-year old boy who also had pulmonary valve endocarditis secondary to acute osteomyelitis. Owing to the evolutive risks inherent in the diverticulum and to the persistence of highly mobile pulmonary valve vegetations 5 years after the initial infectious episode, surgical treatment of the lesions had to be performed. The diagnostic, evolutive and therapeutic problems raised by right ventricular diverticula are discussed.
- Published
- 1988
20. Radiological exploration of the facial canal.
- Author
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Dulac GL, Estrade G, and Doyon D
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- Ear Diseases diagnostic imaging, Humans, Cranial Nerve Neoplasms diagnostic imaging, Facial Nerve, Temporal Bone diagnostic imaging, Tomography, X-Ray
- Published
- 1980
21. [Thrombosis of a mitral valve prosthesis in thrombopenia induced by heparin. Fibrinolytic treatment].
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Bernasconi F, Metivet F, Estrade G, Garnier D, and Donatien Y
- Subjects
- Adult, Female, Humans, Mitral Valve, Streptokinase therapeutic use, Thrombosis drug therapy, Heart Valve Prosthesis, Heparin adverse effects, Thrombocytopenia chemically induced, Thrombosis etiology
- Published
- 1988
22. [Left ventricule function and sickle-cell anemia. Echocardiographic study].
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Estrade G, Poitrineau O, Bernasconi F, Garnier D, and Donatien Y
- Subjects
- Adolescent, Adult, Anemia, Sickle Cell diagnosis, Anemia, Sickle Cell genetics, Cardiomegaly diagnosis, Echocardiography, Heterozygote, Homozygote, Humans, Sickle Cell Trait, Anemia, Sickle Cell physiopathology, Heart Ventricles physiopathology
- Abstract
The dimensions of the cardiac chambers and left ventricular function were studied by echocardiography in 40 patients with homozygous sickle cell disease (SS) and 25 patients with heterozygous sickle cell trait (12 AS, 10 SC, 3 BS) and compared with the same parameters in 30 normal subjects. Patients with homozygous SS disease had significantly larger left atrial (32.2 +/- 6.47 mm vs 26.62 +/- 5.64 mm; p less than 0.001), left ventricular (46.4 +/- 8.49 mm vs 39.97 +/- 5.29 mm; p less than 0.001) and right ventricular (17.95 +/- 5.08 mm vs 15.5 +/- 3.17 mm; p less than 0.02) dimensions: they also had higher indexed myocardial surfaces (11.48 +/- 2.36 cm2/m2 vs 8.21 +/- 1.97 cm2/m2; p less than 0.001) and indexed end diastolic left ventricular volumes (101.84 +/- 22.74 ml/m2 vs 65.05 +/- 10.81 ml/m2; p less than 0.001), a higher cardiac index (4.77 +/- 1.33 l/mn/m2 vs 3.58 +/- 1.08 l/mn/m2; p less than 0.001) and stroke volume (71.77 +/- 32.86 ml vs 49.56 +/- 13.39 ml; p less than 0.001). Peripheral resistances were significantly lower (1341 +/- 469 vs 1626 +/- 368 dynes/s/cm-5; p less than 0.01) as were the velocities of circumferential fibre shortening (VCF) (1.11 +/- 0.20 circ/s vs 1.28 +/- 0.24 circ/s; p less than 0.01). Two thirds of homozygous SS disease patients (27/40) had appearances of an anaemic heart with eccentric left ventricular hypertrophy, normal left ventricular systolic function, an increased cardiac index (5.01 +/- 1.19 l/mn/m2) and low peripheral arterial resistances.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1989
23. [Chloroquine neuromyopathy. One case in prophylactic maleriatherapy (author's transl)].
- Author
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Lhermitte F, Marteau R, Chedru F, Mallecourt J, Estrade G, Godet-Guillain J, and Chevallay M
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- Adult, Chloroquine administration & dosage, Humans, Male, Muscles pathology, Muscular Diseases pathology, Chloroquine adverse effects, Malaria prevention & control, Muscular Diseases chemically induced, Peripheral Nervous System Diseases chemically induced
- Abstract
A case of neuromyopathy due to chronic chloroquine intoxication is reported. The neuromyopathy developped 9 months after malaria suppression therapy with chloroquine was started. The clinical picture was that of a peripherical neuropathy in the lower limbs and of a generalized myasthenic syndrome. Muscular biopsy showed typical pictures of "vacuolar myopathy". The metabolism of the drug was normal. The patient improved soon after chloroquine was discontinued.
- Published
- 1977
24. [Pulmonary embolism and disseminated intravascular coagulation after being bitten by a Bothrops lanceolatus snake. Apropos of a case].
- Author
-
Estrade G, Garnier D, Bernasconi F, and Donatien Y
- Subjects
- Adult, Antivenins therapeutic use, Blood Coagulation drug effects, Contraceptives, Oral, Hormonal, Disseminated Intravascular Coagulation drug therapy, Drug Synergism, Female, Heparin therapeutic use, Humans, Pulmonary Embolism drug therapy, Disseminated Intravascular Coagulation etiology, Pulmonary Embolism etiology, Snake Bites complications, Snake Venoms pharmacokinetics
- Abstract
The authors report the case of a Bothrops lanceolatus snake bite complicated by severe pulmonary embolism a few hours after admission. This thromboembolic complication developed despite heparin therapy and was followed by disseminated intravascular coagulation (DIC). Vascular thrombosis and pulmonary embolism are rare after Bothrops lanceolatus snake bite as patients are usually hypocoagulable due to DIC. In this case, the thromboembolism was probably caused by the procoagulant effect of the thrombin-like enzymes of the snake venom which may have been injected directly into the vein of a young woman taking a contraceptive pill. A specific antivenin which has recently become available fort treatment may decrease the complications of Bothrops lanceolatus snake bite.
- Published
- 1989
25. [Notes on the clinical aspects of embryonic sympathomas in children].
- Author
-
FONTAN A, VERGER P, LEGER H, and ESTRADE G
- Subjects
- Child, Humans, Infant, Neuroblastoma
- Published
- 1959
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