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1. Site-specific fluorescence double-labeling of proteins and analysis of structural changes in solution by Fluorescence Resonance Energy Transfer (FRET)

Author

Meera J. Patel, Gulden Yilmaz, Lavesh Bhatia, Esther E. Biswas-Fiss, and Subhasis B. Biswas

Subjects
Science
Abstract

Fluorescence Resonance Energy Transfer (FRET) is a well-known methodology for detection and quantitation of structural changes of proteins in solution. FRET requires site-specific protein labeling with two fluorophores, one of which functions as an energy donor and the other one as an energy acceptor. However, the site-specific labeling of protein is often complex and difficult, particularly when inserting two fluorophores in specific sites. We have examined several protein labeling approaches with a varying degree of success. Described here is a dual labeling strategy that worked reproducibly in a number of protein targets and we believe will be applicable to a variety of proteins, which have few or no native cysteine (Cys) residues. We have successfully double-labeled DnaA protein of Bacillus anthracis, which lacks intrinsic Cys residues. A cysteine residue was inserted at the N-terminus by in vitro mutagenesis and a Cys-Cys-Phe-Gly-Cys-Cys (CCPGCC) sequence at the C-terminus by PCR. This protein was labeled site-specifically with a fluorescein derivative, FlAsH, at the CCPGCC sequence followed by Alexa568 maleimide at the N-terminus Cys residue. Structural changes of the protein with nucleotide, DNA and an inhibitor protein binding were determined by FRET analysis of the double-labeled protein. This comprehensive novel methodology for site-specific protein labeling with different fluorophores is applicable for understanding different in vitro proteomic structural studies. Here, we describe a verified technique used for FRET spectral analysis and quantitative evaluation of structural changes using fluorophore labeled DnaA protein constructs as an example. Method name: Site-specific fluorescence labeling of proteins and analysis of structural changes in solution by Fluorescence Resonance Energy Transfer (FRET), Keywords: FRET analysis, FlAsH, Alexa568 maleimide, steady-state photon counting spectrofluorometer, Site-specific labeling, intramolecular distance determination, conformational changes

Published
2018
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2. Protein–DNA Interactions Regulate Human Papillomavirus DNA Replication, Transcription, and Oncogenesis

Author

Roxanne Evande, Anshul Rana, Esther E. Biswas-Fiss, and Subhasis B. Biswas

Subjects
Inorganic Chemistry, Organic Chemistry, General Medicine, Physical and Theoretical Chemistry, Molecular Biology, Spectroscopy, Catalysis, Computer Science Applications
Abstract

Human papillomavirus (HPV) is a group of alpha papillomaviruses that cause various illnesses, including cancer. There are more than 160 types of HPV, with many being “high-risk” types that have been clinically linked to cervical and other types of cancer. “Low-risk” types of HPV cause less severe conditions, such as genital warts. Over the past few decades, numerous studies have shed light on how HPV induces carcinogenesis. The HPV genome is a circular double-stranded DNA molecule that is approximately 8 kilobases in size. Replication of this genome is strictly regulated and requires two virus-encoded proteins, E1 and E2. E1 is a DNA helicase that is necessary for replisome assembly and replication of the HPV genome. On the other hand, E2 is responsible for initiating DNA replication and regulating the transcription of HPV-encoded genes, most importantly the E6 and E7 oncogenes. This article explores the genetic characteristics of high-risk HPV types, the roles of HPV-encoded proteins in HPV DNA replication, the regulation of transcription of E6 and E7 oncogenes, and the development of oncogenesis.

Published
2023
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3. Structural and Pathogenic Impacts of ABCA4 Variants in Retinal Degenerations—An In-Silico Study

Author

Senem Cevik, Subhasis B. Biswas, and Esther E. Biswas-Fiss

Subjects
Inorganic Chemistry, ABCA4, missense variant, VUS, protein modeling, pathogenicity prediction, AlphaFold2, Organic Chemistry, General Medicine, Physical and Theoretical Chemistry, Molecular Biology, Spectroscopy, Catalysis, Computer Science Applications
Abstract

The retina-specific ATP-binding cassette transporter protein ABCA4 is responsible for properly continuing the visual cycle by removing toxic retinoid byproducts of phototransduction. Functional impairment caused by ABCA4 sequence variations is the leading cause of autosomal recessive inherited retinal disorders, including Stargardt disease, retinitis pigmentosa, and cone-rod dystrophy. To date, more than 3000 ABCA4 genetic variants have been identified, approximately 40 percent of which have not been able to be classified for pathogenicity assessments. This study examined 30 missense ABCA4 variants using AlphaFold2 protein modeling and computational structure analysis for pathogenicity prediction. All variants classified as pathogenic (n = 10) were found to have deleterious structural consequences. Eight of the ten benign variants were structurally neutral, while the remaining two resulted in mild structural changes. This study’s results provided multiple lines of computational pathogenicity evidence for eight ABCA4 variants of uncertain clinical significance. Overall, in silico analyses of ABCA4 can provide a valuable tool for understanding the molecular mechanisms of retinal degeneration and their pathogenic impact.

Published
2023
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5. Functional significance of the conserved C-Terminal VFVNFA motif in the retina-specific ABC transporter, ABCA4, and its role in inherited visual disease

Author

Meera J. Patel, Esther E. Biswas-Fiss, and Subhasis B. Biswas

Subjects
0301 basic medicine, genetic structures, Amino Acid Motifs, Vision Disorders, Biophysics, ABCA4, ATP-binding cassette transporter, Biology, Biochemistry, Retina, Structure-Activity Relationship, 03 medical and health sciences, Adenosine Triphosphate, 0302 clinical medicine, Protein Domains, medicine, Humans, Amino Acid Sequence, Molecular Biology, Gene, Conserved Sequence, Genetics, chemistry.chemical_classification, Hydrolysis, Genetic Diseases, Inborn, Dystrophy, Cell Biology, Macular dystrophy, medicine.disease, eye diseases, Amino acid, Stargardt disease, Kinetics, 030104 developmental biology, chemistry, Organ Specificity, 030220 oncology & carcinogenesis, biology.protein, ATP-Binding Cassette Transporters, Visual phototransduction
Abstract

The human retina-specific ATP binding cassette transporter, ABCA4, plays a significant role in the visual cycle. Mutations in the ABCA4 gene result in a broad spectrum of severe, blinding, retinal degenerative diseases, including Stargardt macular dystrophy, fundus flavimaculatus, autosomal recessive (ar)-retinitis pigmentosa, and ar-cone-rod dystrophy. Genetic testing frequently yields novel variants of unknown significance, making accurate prognosis and therapeutic approaches difficult. Recently, we have reported a novel variant of ABCA4 corresponding to a four-nucleotide deletion which led to a premature stop codon and loss of the last 161 amino acids, including the highly-conserved VFVNFA motif. Despite the presence of this motif among other ABCA proteins, knowledge of the functional significance of this sequence remains limited. In this study, we have conducted structural and functional analyses of recombinant ABCA4 polypeptides with altered VFVNFA motifs to evaluate the importance of this sequence. Further investigation of ABCA4 subdomain interactions, using Fluorescence Resonance Energy Transfer, demonstrated a loss of interaction between nucleotide binding domains in the absence of the VFVNFA motif.

Published
2019
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6. Genetic variations in the DNA replication origins of human papillomavirus family correlate with their oncogenic potential

Author

Subhasis B. Biswas, Esther E. Biswas-Fiss, and Gulden Yilmaz

Subjects
DNA Replication, 0301 basic medicine, Carcinogenesis, Viral protein, viruses, Cell, Biophysics, Replication Origin, Biology, medicine.disease_cause, Biochemistry, DNA-binding protein, Viral Proteins, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Neoplasms, Sequence Homology, Nucleic Acid, medicine, Humans, Electrophoretic mobility shift assay, Binding site, Papillomaviridae, Molecular Biology, Genetics, Base Sequence, Virulence, DNA replication, Genetic Variation, virus diseases, Oncogene Proteins, Viral, female genital diseases and pregnancy complications, DNA replication origin, DNA-Binding Proteins, 030104 developmental biology, medicine.anatomical_structure, Replication Initiation, 030220 oncology & carcinogenesis, Host-Pathogen Interactions
Abstract

Human papillomaviruses (HPVs) encompass a large family of viruses that range from benign to highly carcinogenic. The crucial differences between benign and carcinogenic types of HPV remain unknown, except that the two HPV types differ in the frequency of DNA replication. We have systematically analyzed the mechanism of HPV DNA replication initiation in low-risk and high-risk HPVs. Our results demonstrate that HPV-encoded E2 initiator protein and its four binding sites in the replication origin play pivotal roles in determining the destiny of the HPV-infected cell. We have identified strain-specific single nucleotide variations in E2 binding sites found only in the high-risk HPVs. We have demonstrated that these variations result in attenuated formation of the E2-DNA complex. E2 binding to these sites is linked to the activation of the DNA replication origin as well as initiation of DNA replication. Both electrophoretic mobility shift assay and atomic force microscopy studies demonstrated that binding of E2 from either low- or high-risk HPVs with variant binding sequences lacked multimeric E2-DNA complex formation in vitro. These results provided a molecular basis of differential DNA replication in the two types of HPVs and pointed to a correlation with the development of cancer.

Published
2018
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7. Site-specific fluorescence double-labeling of proteins and analysis of structural changes in solution by Fluorescence Resonance Energy Transfer (FRET)

Author

Lavesh Bhatia, Subhasis B. Biswas, Meera J. Patel, Esther E. Biswas-Fiss, and Gulden Yilmaz

Subjects
0301 basic medicine, Fluorophore, Clinical Biochemistry, FRET analysis, 7. Clean energy, 03 medical and health sciences, Residue (chemistry), chemistry.chemical_compound, 0302 clinical medicine, Biochemistry, Genetics and Molecular Biology, lcsh:Science, FlAsH, ComputingMethodologies_COMPUTERGRAPHICS, Alexa568 maleimide, Chemistry, Mutagenesis, Inhibitor protein, DnaA, 3. Good health, Medical Laboratory Technology, 030104 developmental biology, Förster resonance energy transfer, Site-specific labeling, intramolecular distance determination, conformational changes, Biophysics, lcsh:Q, steady-state photon counting spectrofluorometer, 030217 neurology & neurosurgery, DNA, Site-specific fluorescence labeling of proteins and analysis of structural changes in solution by Fluorescence Resonance Energy Transfer (FRET), Cysteine
Abstract

Graphical abstract, Highlights • Insertion of a Cys4 sequence and single Cys motif allowedsite-specific labeling with FlAsH and Alexa568 of a protein. • FRET is a well-known technique useful for analysis of structural changes of proteins labeled with donor and accepter fluorophores. • Inter-fluorophore distances and proximity ratios of the peakintensities are used to understand structural changes., Fluorescence Resonance Energy Transfer (FRET) is a well-known methodology for detection and quantitation of structural changes of proteins in solution. FRET requires site-specific protein labeling with two fluorophores, one of which functions as an energy donor and the other one as an energy acceptor. However, the site-specific labeling of protein is often complex and difficult, particularly when inserting two fluorophores in specific sites. We have examined several protein labeling approaches with a varying degree of success. Described here is a dual labeling strategy that worked reproducibly in a number of protein targets and we believe will be applicable to a variety of proteins, which have few or no native cysteine (Cys) residues. We have successfully double-labeled DnaA protein of Bacillus anthracis, which lacks intrinsic Cys residues. A cysteine residue was inserted at the N-terminus by in vitro mutagenesis and a Cys-Cys-Phe-Gly-Cys-Cys (CCPGCC) sequence at the C-terminus by PCR. This protein was labeled site-specifically with a fluorescein derivative, FlAsH, at the CCPGCC sequence followed by Alexa568 maleimide at the N-terminus Cys residue. Structural changes of the protein with nucleotide, DNA and an inhibitor protein binding were determined by FRET analysis of the double-labeled protein. This comprehensive novel methodology for site-specific protein labeling with different fluorophores is applicable for understanding different in vitro proteomic structural studies. Here, we describe a verified technique used for FRET spectral analysis and quantitative evaluation of structural changes using fluorophore labeled DnaA protein constructs as an example.

Published
2018
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8. Aurora Kinases

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, Claude Prigent, Institut de Génétique et Développement de Rennes (IGDR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
0303 health sciences, 03 medical and health sciences, 0302 clinical medicine, [SDV]Life Sciences [q-bio], 030220 oncology & carcinogenesis, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology
Abstract

International audience

Published
2018
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9. ABCA Transporters

Author

Esther E. Biswas-Fiss, Albtool Alturkestani, Jazzlyn Jones, Joscelyn Korth, Stephanie Affet, Malissa Ha, and Subhasis Biswas

Subjects
0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030217 neurology & neurosurgery
Published
2018
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10. Multiple conformational states of DnaA protein regulate its interaction with DnaA boxes in the initiation of DNA replication

Author

S. B. Biswas, Lavesh Bhatia, Meera J. Patel, Esther E. Biswas-Fiss, and Gulden Yilmaz

Subjects
0301 basic medicine, DNA Replication, Models, Molecular, genetic processes, 030106 microbiology, Biophysics, Biology, Pre-replication complex, Biochemistry, 03 medical and health sciences, Adenosine Triphosphate, Bacterial Proteins, Fluorescence Resonance Energy Transfer, Molecular Biology, dnaB helicase, DNA replication, DNA, DnaA, Cell biology, Protein Structure, Tertiary, DNA-Binding Proteins, 030104 developmental biology, Prokaryotic DNA replication, Replication Initiation, health occupations, bacteria, Replisome, Origin recognition complex
Abstract

DnaA protein is the initiator of genomic DNA replication in prokaryotes. It binds to specific DNA sequences in the origin of DNA replication and unwinds small AT-rich sequences downstream for the assembly of the replisome. The mechanism of activation of DnaA that enables it to bind and organize the origin DNA and leads to replication initiation remains unclear. In this study, we have developed double-labeled fluorescent DnaA probes to analyze conformational states of DnaA protein upon binding DNA, nucleotide, and Soj sporulation protein using Fluorescence Resonance Energy Transfer (FRET). Our studies demonstrate that DnaA protein undergoes large conformational changes upon binding to substrates and there are multiple distinct conformational states that enable it to initiate DNA replication. DnaA protein adopted a relaxed conformation by expanding ~15A upon binding ATP and DNA to form the ATP·DnaA·DNA complex. Hydrolysis of bound ATP to ADP led to a contraction of DnaA within the complex. The relaxed conformation of DnaA is likely required for the formation of the multi-protein ATP·DnaA·DNA complex. In the initiation of sporulation, Soj binding to DnaA prevented relaxation of its conformation. Soj·ADP appeared to block the activation of DnaA, suggesting a mechanism for Soj·ADP in switching initiation of DNA replication to sporulation. Our studies demonstrate that multiple conformational states of DnaA protein regulate its binding to DNA in the initiation of DNA replication.

Published
2017

11. Retinoid Binding Properties of Nucleotide Binding Domain 1 of the Stargardt Disease-associated ATP Binding Cassette (ABC) Transporter, ABCA4

Author

Stephanie Affet, Malissa Ha, Esther E. Biswas-Fiss, and Subhasis B. Biswas

Subjects
genetic structures, Retinoid binding, Molecular Sequence Data, ABCA4, ATP-binding cassette transporter, Plasma protein binding, Biology, Biochemistry, Macular Degeneration, Retinoids, Adenosine Triphosphate, Protein structure, Isomerism, medicine, Humans, Amino Acid Sequence, Molecular Biology, Nucleotides, Molecular Bases of Disease, Cell Biology, medicine.disease, Protein Structure, Tertiary, Stargardt disease, Kinetics, Cyclic nucleotide-binding domain, biology.protein, ATP-Binding Cassette Transporters, sense organs, Sequence Alignment, Protein Binding, Binding domain
Abstract

The retina-specific ATP binding cassette transporter, ABCA4 protein, is associated with a broad range of inherited macular degenerations, including Stargardt disease, autosomal recessive cone rod dystrophy, and fundus flavimaculatus. In order to understand its role in retinal transport in rod out segment discs, we have investigated the interactions of the soluble domains of ABCA4 with both 11-cis- and all-trans-retinal. Using fluorescence anisotropy-based binding analysis and recombinant polypeptides derived from the amino acid sequences of the four soluble domains of ABCA4, we demonstrated that the nucleotide binding domain 1 (NBD1) specifically bound 11-cis-retinal. Its affinity for all-trans-retinal was markedly reduced. Stargardt disease-associated mutations in this domain resulted in attenuation of 11-cis-retinal binding. Significant differences in 11-cis-retinal binding affinities were observed between NBD1 and other cytoplasmic and lumenal domains of ABCA4. The results suggest a possible role of ABCA4 and, in particular, the NBD1 domain in 11-cis-retinal binding. These results also correlate well with a recent report on the in vivo role of ABCA4 in 11-cis-retinal transport.

Published
2012
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12. Quantitative analysis of the mechanism of DNA binding by Bacillus DnaA protein

Author

Shawna M. Rotoli, Subhasis B. Biswas, and Esther E. Biswas-Fiss

Subjects
DNA Replication, DNA, Bacterial, Molecular Sequence Data, genetic processes, Fluorescence Polarization, Replication Origin, Biology, Microscopy, Atomic Force, Origin of replication, Pre-replication complex, Biochemistry, Adenosine Triphosphate, Bacterial Proteins, SeqA protein domain, Amino Acid Sequence, dnaB helicase, Binding Sites, Sequence Homology, Amino Acid, Circular bacterial chromosome, DNA replication, General Medicine, Molecular biology, DnaA, Adenosine Diphosphate, DNA-Binding Proteins, Kinetics, Prokaryotic DNA replication, Bacillus anthracis, health occupations, Thermodynamics, bacteria, Hydrophobic and Hydrophilic Interactions, Algorithms, Protein Binding
Abstract

DnaA protein has the sole responsibility of initiating a new round of DNA replication in prokaryotic organisms. It recognizes the origin of DNA replication, and initiates chromosomal DNA replication in the bacterial genome. In Gram-negative Escherichia coli, a large number of DnaA molecules bind to specific DNA sequences (known as DnaA boxes) in the origin of DNA replication, oriC, leading to the activation of the origin. We have cloned, expressed, and purified full-length DnaA protein in large quantity from Gram-positive pathogen Bacillus anthracis (DnaA(BA)). DnaA(BA) was a highly soluble monomeric protein making it amenable to quantitative analysis of its origin recognition mechanisms. DnaA(BA) bound DnaA boxes with widely divergent affinities in sequence and ATP-dependent manner. In the presence of ATP, the K(D) ranged from 3.8 × 10(-8) M for a specific DnaA box sequence to 4.1 × 10(-7) M for a non-specific DNA sequence and decreased significantly in the presence of ADP. Thermodynamic analyses of temperature and salt dependence of DNA binding indicated that hydrophobic (entropic) and ionic bonds contributed to the DnaA(BA)·DNA complex formation. DnaA(BA) had a DNA-dependent ATPase activity. DNA sequences acted as positive effectors and modulated the rate (V(max)) of ATP hydrolysis without any significant change in ATP binding affinity.

Published
2012
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13. Quantitative Analysis of Binding of Single-Stranded DNA by Escherichia coli DnaB Helicase and the DnaB·DnaC Complex

Author

Esther E. Biswas-Fiss and Subhasis B. Biswas

Subjects
Protein Conformation, DNA, Single-Stranded, medicine.disease_cause, Biochemistry, Cofactor, Substrate Specificity, chemistry.chemical_compound, Adenosine Triphosphate, Bacterial Proteins, Escherichia coli, medicine, Nucleotide, dnaB helicase, chemistry.chemical_classification, Base Sequence, biology, Escherichia coli Proteins, Osmolar Concentration, DNA Helicases, Temperature, DNA replication, Adenosine Diphosphate, Crystallography, chemistry, biology.protein, Biophysics, Nucleic Acid Conformation, bacteria, Fluorescein, Primase, DnaB Helicases, dnaC, DNA, Protein Binding
Abstract

DnaB helicase is responsible for unwinding duplex DNA during chromosomal DNA replication and is an essential component of the DNA replication apparatus in Escherichia coli. We have analyzed the mechanism of binding of single-stranded DNA (ssDNA) by the DnaB x DnaC complex and DnaB helicase. Binding of ssDNA to DnaB helicase was significantly modulated by nucleotide cofactors, and the modulation was distinctly different for its complex with DnaC. DnaB helicase bound ssDNA with a high affinity [Kd = (5.09 +/- 0.32) x 10(-8) M] only in the presence of ATPgammaS, a nonhydrolyzable analogue of ATP, but not other nucleotides. The binding was sensitive to ionic strength but not to changes in temperature in the range of 30-37 degrees C. On the other hand, ssDNA binding in the presence of ADP was weaker than that observed with ATPgammaS, and the binding was insensitive to ionic strength. DnaC protein hexamerizes to form a 1:1 complex with the DnaB hexamer and loads it onto the ssDNA by forming a DnaB6 x DnaC6 dodecameric complex. Our results demonstrate that the DnaB6 x DnaC6 complex bound ssDNA with a high affinity [Kd = (6.26 +/- 0.65) x 10(-8) M] in the presence of ATP, unlike the DnaB hexamer. In the presence of ATPgammaS or ADP, binding of ssDNA by the DnaB6 x DnaC6 complex was a lower-affinity process. In summary, our results suggest that in the presence of ATP in vivo, the DnaB6 x DnaC6 complex should be more efficient in binding DNA as well as in loading DnaB onto the ssDNA than DnaB helicase itself.

Published
2006
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14. The Mcm467 Complex of Saccharomyces cerevisiae Is Preferentially Activated by Autonomously Replicating DNA Sequences

Author

Subhasis B. Biswas, Esther E. Biswas-Fiss, and Sujata M. Khopde

Subjects
DNA Replication, Saccharomyces cerevisiae Proteins, Chromosomal Proteins, Non-Histone, ATPase, Deoxyribonucleotides, Molecular Sequence Data, Saccharomyces cerevisiae, Cell Cycle Proteins, Replication Origin, Biochemistry, chemistry.chemical_compound, Adenosine Triphosphate, Replication Protein A, DNA, Fungal, Replication protein A, DNA Primers, Base Sequence, biology, Oligonucleotide, DNA replication, Nuclear Proteins, Helicase, Minichromosome Maintenance Complex Component 7, biology.organism_classification, Minichromosome Maintenance Complex Component 6, Minichromosome Maintenance Complex Component 4, DNA-Binding Proteins, Kinetics, DNA helicase activity, chemistry, biology.protein, DNA
Abstract

We have analyzed the role of single-stranded DNA (ssDNA) in the modulation of the ATPase activity of Mcm467 helicase of the yeast Saccharomyces cerevisiae. The ATPase activity of the Mcm467 complex is modulated in a sequence-specific manner and that the ssDNA sequences derived from the origin of DNA replication of S. cerevisiae autonomously replicating sequence 1 (ARS1) are the most effective stimulators. Synthetic oligonucleotides, such as oligo(dA) and oligo(dT), also stimulated the ATPase activity of the Mcm467 complex, where oligo(dT) was more effective than oligo(dA). However, the preference of a thymidine stretch appeared unimportant, because with yeast ARS1 derived sequences, the A-rich strand was as effective in stimulating the ATPase activity, as was the T-rich strand. Both of these strands were more effective stimulators than either oligo(dA)( )()or oligo(dT). The DNA helicase activity of Mcm467 complex is also significantly stimulated by the ARS1-derived sequences. These results indicate that the ssDNA sequences containing A and B1 motifs of ARS1, activate the Mcm467 complex and stimulate its ATPase and DNA helicase activities. Our results also indicate that the yeast replication protein A stimulated the ATPase activity of the Mcm467 complex.

Published
2005
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15. Modulation of DNA Synthesis in Saccharomyces cerevisiae Nuclear Extract by DNA Polymerases and the Origin Recognition Complex

Author

Atanaska V. Mitkova, Esther E. Biswas-Fiss, and Subhasis B. Biswas

Subjects
DNA Replication, Saccharomyces cerevisiae Proteins, DNA polymerase, DNA polymerase II, Origin Recognition Complex, DNA-Directed DNA Polymerase, Saccharomyces cerevisiae, Biochemistry, Molecular Biology, DNA Polymerase III, DNA clamp, Cell-Free System, biology, DNA, Superhelical, DNA replication, Cell Biology, Processivity, Minichromosome Maintenance 1 Protein, DNA Polymerase I, Molecular biology, DNA-Binding Proteins, DNA Topoisomerases, Type I, biology.protein, DNA supercoil, Primase, DNA Topoisomerases, In vitro recombination, Transcription Factors
Abstract

We have analyzed the modulation of DNA synthesis on a supercoiled plasmid DNA template by DNA polymerases (pol), minichromosome maintenance protein complex (Mcm), topoisomerases, and the origin recognition complex (ORC) using an in vitro assay system. Antisera specific against the four-subunit pol alpha, the catalytic subunit of pol delta, and the Mcm467 complex each inhibited DNA synthesis. However, DNA synthesis in this system appeared to be independent of polepsilon. Consequently, DNA synthesis in the in vitro system appeared to depend only on two polymerases, alpha and delta, as well as the Mcm467 DNA helicase. This system requires supercoiled plasmid DNA template and DNA synthesis absolutely required DNA topoisomerase I. In addition, we also report here a novel finding that purified recombinant six subunit ORC significantly stimulated the DNA synthesis on a supercoiled plasmid DNA template containing an autonomously replicating sequence, ARS1.

Published
2005
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16. Quantitative analysis of nucleotide modulation of DNA binding by DnaC protein of Escherichia coli

Author

Subhasis B. Biswas, Stephen Flowers, and Esther E. Biswas-Fiss

Subjects
DNA, Single-Stranded, Biosensing Techniques, Biology, Models, Biological, Biochemistry, Fluorescence, chemistry.chemical_compound, Adenosine Triphosphate, Bacterial Proteins, Escherichia coli, Nucleotide, Molecular Biology, dnaB helicase, chemistry.chemical_classification, Escherichia coli Proteins, DNA Helicases, Temperature, DNA replication, Helicase, Cell Biology, DnaA, Adenosine Diphosphate, Kinetics, chemistry, Replication Initiation, biology.protein, Anisotropy, Thermodynamics, DnaB Helicases, dnaC, DNA, Research Article
Abstract

In this study, we have presented the first report of Escherichia coli DnaC protein binding to ssDNA (single stranded DNA) in an apparent hexameric form. DnaC protein transfers DnaB helicase onto a nascent chromosomal DNA replication fork at oriC, the origin of E. coli DNA replication. In eukaryotes, Cdc6 protein may play a similar role in the DNA helicase loading in the replication fork during replication initiation at the origin. We have analysed the DNA-binding properties of DnaC protein and a quantitative analysis of the nucleotide regulation of DnaC–DNA and DnaC–DnaB interactions using fluorescence anisotropy and affinity sensor analysis. DnaC protein bound to ssDNA with low to moderate affinity and the affinity was strictly modulated by nucleotides. DnaC bound ssDNA in the complete absence of nucleotides. The DNA-binding affinity was significantly increased in the presence of ATP, but not ATP[S]. In the presence of ADP, the binding affinity decreased approximately fifty-fold. Both anisotropy and biosensor analyses demonstrated that with DnaC protein, ATP facilitated ssDNA binding, whereas ADP facilitated its dissociation from ssDNA, which is a characteristic of an ATP/ADP switch. Both ssDNA and nucleotides modulate DnaB6•DnaC6 complex formation, which has significant implications in DnaC protein function. Based on the thermodynamic data provided in this study, we have proposed a mechanism of DnaB loading on to ssDNA by DnaC protein.

Published
2004
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17. Adaptor-Related Protein Complex 4

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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18. Apolipoprotein Receptor (APR)

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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19. Alpha E Integrin

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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20. ACK1

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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21. Alpha v Integrin

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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22. ADP Ribosylation Factor GTPase-Activating Protein 1

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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23. A-Kinase Anchoring Protein (AKAP)

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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24. Adenylate Cyclase 9

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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25. AIFM1 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1)

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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26. Angiotensin II Type 2 Receptor Interacting Protein (ATIP)

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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27. ADP-Ribosyl Cyclase

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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28. Adenomatous Polyposis Coli

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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29. ABCR and Rim Protein (for ABCA4)

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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30. ADP-Ribosylation Factor-Like 10C

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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31. ADP/ATP carrier

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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32. ARF-GAP, RHO-GAP, Ankyrin Repeat, and Plekstrin Homology Domains Containing Protein 3

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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33. ADP-Ribosylation Factor-Like 8B

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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34. Adenine Nucleotide Translocase

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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35. ATP Diphosphohydrolase

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

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2012
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36. AP-3

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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37. Angiotensin Type 2 Receptor

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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38. ASK (Activator of S Phase Kinase)/huDbf4 (Human)

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

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2012
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39. Acidic FGF

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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40. Arf-Domain Protein

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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41. ABCA Transporters

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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42. Arf-Like Protein 8B

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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43. Angiotensin II Receptor Type 2

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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44. A1 (BCL2-Related Protein A1), BFL-1, BCL2L5 (BCL-2 like 5)

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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45. Activators of G-Protein Signaling (AGS)

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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46. AbaA (Aspergillus nidulans)

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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47. Adhesion GPCRs

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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48. A-Protein

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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49. ADP-Ribosylation Factor

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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50. Arachidonic Acid

Author

Esther E. Biswas-Fiss, Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, Benjamin J. Gosney, Venkateswarlu Kanamarlapudi, Ferenc András Antoni, Carmen W. Dessauer, Rachna Sadana, Christiane Kirchhoff, Ben Davies, Nazanine Modjtahedi, Guido Kroemer, Graeme K. Carnegie, John D. Scott, Bryan A. Anthony, Gregg A. Hadley, Hatice Zeynep Kirli, Martina Tesikova, Fahri Saatcioglu, Søren Paludan Sheikh, Grégory Tufo, Lorenzo Galluzzi, Catherine Brenner, Andrew A. Peden, Shinji Matsuda, Michisuke Yuzaki, Luis Martinez-Lostao, Alberto Anel, Javier Naval, Jens Rauch, Walter Kolch, Siân-Eleri Owens, Joel Moss, Martha Vaughan, Moran Rawet-Slobodkin, Deike Hesse, Alexander Jaschke, Annette Schürmann, Katherine Figella, Brad Allen Bryan, Mingyao Liu, Aiysha Thompson, Tsonwin Hai, Johnna Dominick, Kun Huang, David Reboutier, and Claude Prigent

Published
2012
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