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937 results on '"Esteves, M."'

1. First light of the Integral Field Unit of GRIS on the GREGOR solar telescope

Author

Dominguez-Tagle, C., Collados, M., Lopez, R., Cedillo, J. J. Vaz, Esteves, M. A., Grassin, O., Vega, N., Mato, A., Quintero, J., Rodriguez, H., Regalado, S., and Gonzalez, F.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract

An Integral Field Unit (IFU) based on image-slicers has been added to the GREGOR Infrared Spectrograph (GRIS). This upgrade to the instrument makes possible 2D spectropolarimetry in the near-infrared by simultaneously recording the full Stokes profiles of spectral lines (in a given spectral interval) at all the points in the field of view. It provides high-cadence spectropolarimetric observations at the instrument's high spatial resolution and high polarization sensitivity at the GREGOR solar telescope. The IFU is ideal for observing the polarized spectrum of fast-evolving solar features at high spatial and spectral resolutions. The high observing cadence opens the possibility of time-series observations. The analysis of observations to this level of accuracy is essential for understanding the complex dynamics and interactions of solar plasma and magnetic fields. The image slicer of the IFU has eight slices of width 100 micron, covering a total field of view of 6" x 3". It was designed and built within the framework of the European projects SOLARNET and GREST, as a prototype for future instruments of the European Solar Telescope (EST) and was integrated into GRIS. After two commissioning campaigns in 2017 and 2018, the IFU was finally installed at the end of September 2018 and offered to all observers who use the telescope.

Published
2022
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2. Team-Based Learning to Enhance Student’ Competencies in a Fluid Mechanics Module

Author

Sena-Esteves, M. Teresa, Ribeiro, Margarida, Morais, Cristina, Brás-Pereira, Isabel, Guedes, Anabela, Soares, Filomena, Leão, Celina P., Huang, Ronghuai, Series Editor, Kinshuk, Series Editor, Jemni, Mohamed, Series Editor, Chen, Nian-Shing, Series Editor, Spector, J. Michael, Series Editor, García-Peñalvo, Francisco José, editor, and García-Holgado, Alicia, editor

Published
2023
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4. An Assessment of the Weight of the Experimental Component in Physics and Chemistry Classes

Author

Figueiredo, Margarida, Esteves, M. Lurdes, Chaves, Humberto, Neves, José, Vicente, Henrique, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Le Thi, Hoai An, editor, Pham Dinh, Tao, editor, and Le, Hoai Minh, editor

Published
2022
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5. Florid cutaneous papillomatosis as a marker of neoplastic recurrence

Author

Esteves, M, Antunes, I, and Azevedo, F

Subjects
florid cutaneous papillomatosis, paraneoplastic dermatosis, gastric adenocarcinoma
Abstract

Florid cutaneous papillomatosis is a rare paraneoplastic dermatosis, most commonly associated with gastric adenocarcinoma. It is characterized by a sudden onset of hyperkeratotic papules, clinically indistinguishable from viral warts. We report an 80-year-old man who presented to our department with a two-month history of multiple verrucous lesions affecting the face, perioral region, and hands. Two years before, he was treated for a gastric adenocarcinoma with a subtotal gastrectomy, but showed no evidence of residual disease or recurrence. Given the clinical background, a diagnosis of florid cutaneous papillomatosis was considered. Skin biopsy excluded a viral origin, and tumour recurrence was later identified through an abdominal ultrasound. The onset of this entity is typically prior or concurrent with the diagnosis of the internal malignancy, but it may also represent the first sign of recurrence of a previously treated neoplasm. Its early recognition is essential to ensure a thorough investigation and prompt treatment.

Published
2018

21. Lab Classes in Chemistry Learning an Artificial Intelligence View

Author

Figueiredo, Margarida, Esteves, M. Lurdes, Neves, José, Vicente, Henrique, Kacprzyk, Janusz, Series editor, de la Puerta, José Gaviria, editor, Ferreira, Iván García, editor, Bringas, Pablo Garcia, editor, Klett, Fanny, editor, Abraham, Ajith, editor, de Carvalho, André C.P.L.F., editor, Herrero, Álvaro, editor, Baruque, Bruno, editor, Quintián, Héctor, editor, and Corchado, Emilio, editor

Published
2014
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31. Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis

Author

Medinas, D. B. (Danilo Bilches), Malik, S. (Sajid), Yıldız-Bölükbaşı, E. (Esra), Borgonovo, J. (Janina), Saaranen, M. J. (Mirva J), Urra, H. (Hery), Pulgar, E. (Eduardo), Afzal, M. (Muhammad), Contreras, D. (Darwin), Wright, M. T. (Madison T), Bodaleo, F. (Felipe), Quiroz, G. (Gabriel), Rozas, P. (Pablo), Mumtaz, S. (Sara), Díaz, R. (Rodrigo), Rozas, C. (Carlos), Cabral-Miranda, F. (Felipe), Piña, R. (Ricardo), Valenzuela, V. (Vicente), Uyan, O. (Ozgun), Reardon, C. (Christopher), Woehlbier, U. (Ute), Brown, R. H. (Robert H), Sena-Esteves, M. (Miguel), Gonzalez-Billault, C. (Christian), Morales, B. (Bernardo), Plate, L. (Lars), Ruddock, L. W. (Lloyd W), Concha, M. L. (Miguel L), Hetz, C. (Claudio), Tolun, A. (Aslıhan), Medinas, D. B. (Danilo Bilches), Malik, S. (Sajid), Yıldız-Bölükbaşı, E. (Esra), Borgonovo, J. (Janina), Saaranen, M. J. (Mirva J), Urra, H. (Hery), Pulgar, E. (Eduardo), Afzal, M. (Muhammad), Contreras, D. (Darwin), Wright, M. T. (Madison T), Bodaleo, F. (Felipe), Quiroz, G. (Gabriel), Rozas, P. (Pablo), Mumtaz, S. (Sara), Díaz, R. (Rodrigo), Rozas, C. (Carlos), Cabral-Miranda, F. (Felipe), Piña, R. (Ricardo), Valenzuela, V. (Vicente), Uyan, O. (Ozgun), Reardon, C. (Christopher), Woehlbier, U. (Ute), Brown, R. H. (Robert H), Sena-Esteves, M. (Miguel), Gonzalez-Billault, C. (Christian), Morales, B. (Bernardo), Plate, L. (Lars), Ruddock, L. W. (Lloyd W), Concha, M. L. (Miguel L), Hetz, C. (Claudio), and Tolun, A. (Aslıhan)

Abstract

Recessive gene mutations underlie many developmental disorders and often lead to disabling neurological problems. Here, we report identification of a homozygous c.170G>A (p.Cys57Tyr or C57Y) mutation in the gene coding for protein disulfide isomerase A3 (PDIA3, also known as ERp57), an enzyme that catalyzes formation of disulfide bonds in the endoplasmic reticulum, to be associated with syndromic intellectual disability. Experiments in zebrafish embryos show that PDIA3C57Y expression is pathogenic and causes developmental defects such as axonal disorganization as well as skeletal abnormalities. Expression of PDIA3C57Y in the mouse hippocampus results in impaired synaptic plasticity and memory consolidation. Proteomic and functional analyses reveal that PDIA3C57Y expression leads to dysregulation of cell adhesion and actin cytoskeleton dynamics, associated with altered integrin biogenesis and reduced neuritogenesis. Biochemical studies show that PDIA3C57Y has decreased catalytic activity and forms disulfide-crosslinked aggregates that abnormally interact with chaperones in the endoplasmic reticulum. Thus, rare disease gene variant can provide insight into how perturbations of neuronal proteostasis can affect the function of the nervous system.

Published
2022

32. The role of ocean and atmospheric dynamics in the marine-based collapse of the last Eurasian Ice Sheet

Author

Sejrup, H. P. (Hans Petter), Hjelstuen, B. O. (Berit Oline), Patton, H. (Henry), Esteves, M. (Mariana), Winsborrow, M. (Monica), Rasmussen, T. L. (Tine Lander), Andreassen, K. (Karin), Hubbard, A. (Alun), Sejrup, H. P. (Hans Petter), Hjelstuen, B. O. (Berit Oline), Patton, H. (Henry), Esteves, M. (Mariana), Winsborrow, M. (Monica), Rasmussen, T. L. (Tine Lander), Andreassen, K. (Karin), and Hubbard, A. (Alun)

Abstract

Information from former ice sheets may provide important context for understanding the response of today’s ice sheets to forcing mechanisms. Here we present a reconstruction of the last deglaciation of marine sectors of the Eurasian Ice Sheet, emphasising how the retreat of the Norwegian Channel and the Barents Sea ice streams led to separation of the British-Irish and Fennoscandian ice sheets at c. 18.700 and of the Kara-Barents Sea-Svalbard and Fennoscandian ice sheets between 16.000 and 15.000 years ago. Combined with ice sheet modelling and palaeoceanographic data, our reconstruction shows that the deglaciation, from a peak volume of 20 m of sea-level rise equivalent, was mainly driven by temperature forced surface mass balance in the south, and by Nordic Seas oceanic conditions in the north. Our results highlight the nonlinearity in the response of an ice sheet to forcing and the significance of ocean-ice-atmosphere dynamics in assessing the fate of contemporary ice sheets.

Published
2022

33. Leptospirosis porcina: prevalencia serológica en establecimientos productores de la República Argentina

Author

Jessica Petrakovsky M., Julio Tinao, and Jorge Esteves M.

Subjects
Cerdo, epidemiología, leptospira, leptospirosis, Veterinary medicine, SF600-1100
Abstract

Objetivo. Detectar la presencia de anticuerpos contra Leptospira sp en cerdos que no presentaban sintomatología clínica, pertenecientes a establecimientos de producción porcina ubicados en todo el territorio de la República Argentina. Materiales y métodos. La asignación de predios y muestras se realizó en forma proporcional a los registrados en cada provincia a lo largo de todo el país. En total se estudiaron 1.524 predios, de los cuales se tomaron 19.872 muestras de suero y en la primera etapa se procesaron 3.631 de los mismos. Este estudio toma en consideración zonas identificadas por provincia, municipio y predios. Los sueros fueron analizados por la técnica de MAT (prueba de microaglutinación). Resultados. El 30% de las muestras resultaron positivas a la prueba tamiz empleada (primera etapa del MAT). La mayoría presentó coaglutininas a dos o a tres serovariedades. Al realizar la titulación de los sueros (segunda etapa del MAT), el porcentaje de positividad se mantuvo, siendo los serovares de mayor prevalencia Castellonis e Icterohaemorrhagiae. El 90% de las muestras presentó un título final de 1:200. Conclusiones. La existencia de sueros positivos en todas las provincias indica el contacto de los animales con la leptospira a lo largo de todo el país.

Published
2013

41. P.0515 Amygdala size associates with stress perception

Author

Caetano, I., primary, Amorim, L., additional, Soares, J.M., additional, Ferreira, S., additional, Coelho, A., additional, Reis, J., additional, Santos, N. Correia, additional, Moreira, P. Silva, additional, Marques, P., additional, Magalhães, R., additional, Esteves, M., additional, Picó-Pérez, M., additional, and Sousa, N., additional

Published
2021
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49. Novo modelo de integração de sistemas avançados de energia renovável nos edifícios

Author

Aelenei, Laura Elena, Brites, Maria João, Joyce, A, Esteves, M. Alexandra, Rodrigues, Carlos, Barros, Helio, and Valente, D.

Subjects
Energy storage, Solar energy, Building integration, NZEB, Zero Energy Buildings
Abstract

CIES2020 - XVII Congresso Ibérico e XIII Congresso Ibero-americano de Energia Solar RESUMO: O projeto IDEAS “Novel building Integration Designs for increased Efficiencies in Advanced climatically tunable renewable energy Systems” é um projeto financiado pelo Programa HORIZON2020, multidisciplinar que reúne várias temáticas científicas e competências para o desenvolvimento e demonstração de um novo conceito de design para integração de edifícios. O modelo combina várias tecnologias de energia renovável, incluindo solar fotovoltaica, solar térmica, armazenamento de energia térmica e bombas de calor (aerotérmica e geotérmica) acopladas a piso radiante. No presente trabalho os autores querem partilhar a visão e descrição geral do projeto IDEAS, alguns trabalhos que foram desenvolvidos nas primeiras atividades e tarefas do projeto relativamente à fabricação e testes de camadas luminescentes downshifting (LDS) para o módulo fotovoltaico híbrido PVT com concentrador parabólico composto (CPC), bem como apresentar o modelo numérico de todo o sistema IDEAS que se encontra em desenvolvimento para a análise técnico económica do sistema IDEAS. ABSTRACT: IDEAS project “Novel building Integration Designs for increased Efficiencies in Advanced climatically tunable renewable energy Systems” [1] is a project funded by the HORIZON2020 Program, a multidisciplinary project that brings together various scientific themes and competencies for the development and demonstration of a novel design concept for building integration. The model combines several renewable energy technologies including solar photovoltaic, solar thermal, thermal energy storage, geothermal and air source HP technology coupled with underfloor heating. In this work the authors want to share the vision and the general description of the IDEAS project, work developed in the first activities and tasks of the project regarding the manufacture and testing of luminescent downshifting layers (LDS) for the luminescent compound parabolic concentrator integrated in the IDEAS system, as well as ongoing work on the construction of the numerical model for the technical economic analysis of the IDEAS system info:eu-repo/semantics/publishedVersion

Published
2020

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