1. Neoplastic and pre-neoplastic lesions of the oesophagus and gastro-oesophageal junction
- Author
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Irene Gullo, Alessandro Vanoli, Luca Mastracci, Paola Parente, Michele Paudice, Jacopo Ferro, Francesco Limarzi, Matteo Fassan, Luca Saragoni, Federica Grillo, and Instituto de Investigação e Inovação em Saúde
- Subjects
Tumour regression ,Esophageal Neoplasms ,Precancerous Conditions / diagnosis ,Oesophageal adenocarcinoma ,Review ,Adenocarcinoma / pathology ,tumour regression grade ,Gastroenterology ,Risk Factors ,Daily practice ,Stomach Neoplasms / epidemiology ,Medicine ,Esophageal Neoplasms / pathology ,Tumour regression grade ,Barrett Esophagus / pathology ,medicine.diagnostic_test ,Esophageal Neoplasms / therapy ,Incidence (epidemiology) ,Incidence ,Barrett's dysplasia ,Gastro oesophageal junction ,Adenocarcinoma / epidemiology ,Esophageal Neoplasms / epidemiology ,oesophageal squamous cell carcinoma ,oesophageal dysplasia ,Oesophageal dysplasia ,medicine.medical_specialty ,Barrett’s dysplasia ,oesophageal adenocarcinoma ,Esophagus / pathology ,Stomach Neoplasms / diagnosis ,Adenocarcinoma ,Pathology and Forensic Medicine ,Barrett Esophagus ,Adenocarcinoma / diagnosis ,Esophagus ,Stomach Neoplasms ,Internal medicine ,Biopsy ,Humans ,Metaplasia ,Esophageal Neoplasms / diagnosis ,business.industry ,Oesophageal squamous cell carcinoma ,Barrett Esophagus / epidemiology ,Metaplasia / pathology ,Precancerous Conditions / pathology ,Stomach Neoplasms / therapy ,Neoplasm Grading ,business ,Barrett Esophagus / diagnosis ,Stomach Neoplasms / pathology ,Precancerous Conditions - Abstract
Summary Oesophageal and gastro-oesophageal junction (GOJ) neoplasms, and their predisposing conditions, may be encountered by the practicing pathologist both as biopsy samples and as surgical specimens in daily practice. Changes in incidence of oesophageal squamous cell carcinomas (such as a decrease in western countries) and in oesophageal and GOJ adenocarcinomas (such as a sharp increase in western countries) are being reported globally. New modes of treatment have changed our histologic reports as specific aspects must be detailed such as in post endoscopic resections or with regards to post neo-adjuvant therapy tumour regression grades. The main aim of this overview is therefore to provide an up-to-date, easily available and clear diagnostic approach to neoplastic and pre-neoplastic conditions of the oesophagus and GOJ, based on the most recent available guidelines and literature.
- Published
- 2020