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Background/aim: There is limited information on the pathologic changes in the small airways among obese and nonobese patients with obstructive sleep apnea syndrome (OSAS). Impulse oscillometry (IOS) measures airway resistance and reactance independently of patient effort. This study aimed to compare airway resistance in small airways using IOS between obese and nonobese patients with OSAS. Materials and methods: In this real-life cross-sectional study, demographic information was collected from obese and nonobese subjects diagnosed with moderate and severe OSAS without any other underlying diseases. Spirometry and IOS measurements were conducted, and the values of both groups were statistically analyzed. Results: The nonobese group had a mean age of 45.6 ± 11.7 years (median 45), while the obese group had a mean age of 48.4 ± 9.5 years (median 47.5). The mean body mass index (BMI) for the nonobese group was 26.2 ± 2.1 kg/m2 (median 27 kg/m2), and for the obese group, it was 35.6 ± 6.4 kg/m2 (median 33 kg/m2). Statistically significant differences were observed between the two groups in R5 - R20 percentage, reactance area (AX), and resonant frequency (Fres) values (p < 0.05). Conclusion: Among obese OSAS patients, there is an increase in resistance in small airways as indicated by IOS values. IOS shows promise as a potential screening tool for diagnosing OSAS. [ABSTRACT FROM AUTHOR]

Background: Psoriasis is a common, chronic, inflammatory skin disorder affecting almost 2-3% of the population. Studies on the epidemiological data and the course of the disease have generally been published in pediatric and middle-aged patients, where the disease is more common. This study aimed to provide more insight into the disease and treatment characteristics of psoriasis patients over 65. Materials and Methods: In this retrospective, cross-sectional, single-center, hospital-based study, patients over 65 who visited our department between 01.06.2017 and 01.06.2020 were included. Results: Ninety six patients with psoriasis were admitted to our outpatient clinic during the study period. The mean age of the patients was 69.92±4.73 years. Women and men were equally affected. Almost 9.4% of the patients had psoriatic arthritis. The patients’ mean Psoriasis Area Severity Index score was 8.39±7.11, and the disease duration was 13.76±12.71 years. Nail involvement was detected in 43.8% of the patients. Family history was positive in 19.8% of the patients. Smoking was positive in 28.1% of the patients, and regular alcohol use was positive in 6.3%. Conclusion: The clinical course of psoriasis is usually milder in elderly onset patients. Further studies are warranted to determine the best management of psoriasis in elderly patients. Drug interactions and metabolism should be carefully managed in these patients. [ABSTRACT FROM AUTHOR]