1. Buschke-Löwenstein tumor in childhood: a case report.
- Author
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Ambriz-González G, Escobedo-Zavala LC, Carrillo de la Mora F, Ortiz-Arriaga A, Cordero-Zamora A, Corona-Nakamura A, López Ramírez MK, and Velázquez Ramírez GA
- Subjects
- Antimetabolites, Antineoplastic therapeutic use, Anus Neoplasms surgery, Carcinoma, Verrucous surgery, Child, Condylomata Acuminata surgery, Female, Fluorouracil therapeutic use, Humans, Treatment Outcome, Anus Neoplasms drug therapy, Carcinoma, Verrucous drug therapy, Condylomata Acuminata drug therapy
- Abstract
Buschke-Löwenstein tumor or giant condyloma is a warty verrucous lesion, characterized by slow growth, locally infiltrating and disfiguring lesions. Despite its benign histological appearance and low risk of metastasis, Buschke-Löwenstein tumor is an intermediate lesion between condyloma acuminatum and verrucous carcinoma. It has been linked to human papilloma virus, mainly subtypes 6 and 11. Other factors implicated in this disease include poor hygiene, chronic irritation, promiscuity, and cellular immunocompromised states. It rarely occurs in children. The first line of treatment is radical surgical excision with or without adjuvant chemotherapy. We report the case of a 12-year-old girl with a giant perianal condyloma that was treated with surgical excision and a 6-week course of 5-fluorouracil beginning 6 weeks after surgery, with excellent functional and cosmetic results.
- Published
- 2005
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