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2. Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

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Wright, Naomi Jane, Leather, Andrew J.M., Ade-Ajayi, Niyi, Sevdalis, Nick, Davies, Justine, Poenaru, Dan, Ameh, Emmanuel, Ademuyiwa, Adesoji, Lakhoo, Kokila, Smith, Emily Rose, Douiri, Abdel, Elstad, Maria, Sim, Marcus, Riboni, Cristiana, Martinez-Leo, Bruno, Akhbari, Melika, Tabiri, Stephen, Mitul, Ashrarur, Aziz, Dayang Anita Abdul, Fachin, Camila, Niyukuri, Alliance, Arshad, Muhammad, Ibrahim, Fowzia, Moitt, Natalie, Doheim, Mohamed Fahmy, Thompson, Hannah, Ubhi, Harmony, Williams, Isabelle, Hashim, Sophia, Philipo, Godfrey Sama, Herrera, Laura, Yunus, Aayenah, Vervoort, Dominique, Parker, Samuel, Benaskeur, Yousra-Imane, Alser, Osaid H., Adofo-Ansong, Nana, Alhamid, Ahmad, Salem, Hosni khairy, Saleh, Mahmoud, Elrais, Safa Abdal, Abukhalaf, Sadi, Shinondo, Patricia, Nour, Ibrahim, Aydin, Emrah, Vaitkiene, Agota, Naranjo, Kelly, Dube, Andile Maqhawe, Ngwenya, Sodumisa, Yacoub, Mina A., Kwasau, Henang, Hyman, Gabriella, Elghazaly, Shrouk Mahmoud, Al-Slaibi, Ibrahim, Hisham, Intisar, Franco, Helena, Arbab, Hana, Samad, Lubna, Soomro, Aqil, Chaudhry, Muhammad Amjad, Karim, Safina, Khattak, Muhammad Adnan Khan, Nah, Shireen Anne, Dimatatac, Doris Mae, Choo, Candy SC, Maistry, Niveshni, Mitul, Ashrarur Rahman, Hasan, Samiul, Karim, Sabbir, Yousuf, Hina, Qureshi, Taimur, Nour, Ibrahim Rabi, Al-Taher, Raed Nael, Sarhan, Osama Abdul Kareem, Garcia-Aparicio, Luis, Prat, Jordi, Blazquez-Gomez, Eva, Tarrado, Xavier, Iriondo, Martí, Bragagnini, Paolo, Rite, Segundo, Hagander, Lars, Svensson, Emma, Owusu, Sheila, Abdul-Mumin, Alhassan, Bagbio, Dominic, Ismavel, Vijay Anand, Miriam, Ann, T, Shajin, Anaya Dominguez, Marlene, Ivanov, Monica, Serban, Andreea Madalina, Derbew, Miliard, Elfiky, Mahmoud, Olivos Perez, Maricarmen, Abrunhosa Matias, Marcia, Arnaud, Alexis P, Negida, Ahmed, King, Sebastian, Fazli, Mohamad Rafi, Hamidi, Nadia, Touabti, Souhem, Chipalavela, Rossana Francisco, Lobos, Pablo, Jones, Brendan, Ljuhar, Damir, Singer, Georg, Cordonnier, Annelien, Jáuregui, Lorena, Zvizdic, Zlatan, Wong, Janice, St-Louis, Etienne, Shu, Qiang, Lui, Yang, Correa, Catalina, Pos, Lucie, Alcántara, Elvyn, Féliz, Erick, Zea-Salazar, Luis Enrique, Ali, Liza, Peycelon, Matthieu, Anatole, Nzanzu Kipata, Jallow, Cherno S., Lindert, Judith, Ghosh, Dhruv, Adhiwidjaja, Cathline Freya, Tabari, Ahmad Khaleghnejad, Lotfollahzadeh, Saran, Mussein, Haidar Mohammad, Vatta, Fabrizio, Pasqua, Noemi, Kihiko, David, Gohil, Hetal, Nour, Ibrahim R., Elhadi, Muhammed, Almada, Suad Ahmed, Verkauskas, Gilvydas, Risteski, Toni, Peñarrieta Daher, Alejandro, Outani, Oumaima, Hamill, James, Lawal, Taiwo, Mulu, Jack, Yapo, Benjamin, Saldaña, Lily, Espineda, Beda, Toczewski, Krystian, Tuyishime, Eugene, Ndayishimiye, Isaac, Raboe, Enaam, Hammond, Philip, Walker, Gregor, Djordjevic, Ivona, Chitnis, Milind, Son, Joonhyuk, Lee, Sanghoon, Hussien, Muaad, Malik, Sawazen, Ismail, Enas Musa, Boonthai, Ampaipan, Dahman, Nesrine Ben Hadj, Hall, Nigel, Castedo Camacho, Fabiola Ruth, Sobrero, Helena, Butler, Marilyn, Makhmud, Aliev, Novotny, Nathan, Hammouri, Ahmad G., Al-Rayyes, Maisara, Bvulani, Bruce, Muraveji, Qais, Murzaie, Muhammad Yousuf, Sherzad, Ajmal, Haidari, Sayed Aman, Monawar, Abdul Baqi, Samadi, Dr. Ahmad Zia, Thiessen, Jesh, Venant, Ntakarutimana, Hospital, Sonia Inamuco, Jérémie, Niyonkuru, Mbonicura, Jean Claude, Vianney, Butoyi Jean Marie, Tadesse, Amezene, Negash, Samuel, Roberts, Charles A., Jabang, John N., Bah, Abdoulie, Camamra, Kajali, Correa, Armandou, Sowe, Babucarr, Gai, A., Jaiteh, Musa, Raymond, Kwizera Jean, Mvukiyehe, Jean Paul, Itangishaka, Innocent, Kayibanda, Emmanuel, Manirambona, Emery, Lule, Joseph, Costas-Chavarri, Ainhoa, Shyaka Gashugi, Ian, Ndata, Albert, Gasana, Georges, Nezerwa, Yves Castar, Simeon, Turatsinze, Muragijimana, Jean De Dieu, Rashid, Sakina, Msuya, David, Elisante, Joseph, Solanki, Meghna, Manjira, Emmanuel, Lodhia, Jay, Jusabani, Mubashir, Tarmohamed, Murad, Koipapi, Sengua, Souhem, Touabti, Sara, Nabti, Sihem, Brahimi, Dania, Bouguermouh, Toufik, Iaiche Achour, Mounira, Baghdadi Nour el islam, Habiba, Alouani, Aragão, Liliana, Gonçalves, Victor, Lino Urquizo, Marcelo Mauricio, Varela, Maria Florencia, Mercado, Pedro, Horacio, Bonavia, Damiani, Andrea, Mac, Carlos, Putruele, Daniel, Liljesthrom, Karen, Bernaus, Marianela, Jauri, Cesar, Cripovich, Alejandrina, Bianchin, Ezequiel, Puig, Maria Gabriela, Andreussi, Lorna, Iracelay, Susana, Marcos, Dolores, Herrera, Carina, Palacios, Nelly, Avile, Romina, Serezo, Belen, Montoya, Debora, Cepeda, Rodrigo, Vaquila, Justo, Veronica, Sofficci, Pardo, Liliana, Valeria, Pelussi, Julio, Lapalma, Martin, Aranda Diego, Lucio, Palazzi, Gabriel, Comba, Marianella, Depetrini, Calderón Arancibia, José Alfredo, Huespe, Enrique, Losa, Gabriela Natalia, Arancibia Gutiérrez, Elsa, Scherl, Humberto, Gonzalez, Daniel Emilio, Baistrocchi, Valentina, Silva, Yanina, Galdeano, Marcelo, Medard, Pablo, Sueiras, Ines, Romero Manteola, Enrique, Defago, Victor Hugo, Mieres, Carlos, Alberto, Carlos, Cornelli, Fabio, Molina, Marcelo, Ravetta, Pablo, Patiño Gonzalez, Celeste Carolina, Dallegre, Maria Belen, Szklarz, Maria Tatiana, Leyba, Marcos Federico, Rivarola, Nahuel Ignacio, Charras, Maria Delia, Morales, Adriana, Caseb, Paloma, Toselli, Luzia, Millán, Carolina, Junes, Maria del Carmen, Di Siervi, Oscar, Gilardi, Jose, Simon, Soledad, Contreras, Carla Sofia, Rojas, Nair, Arnoletto, Lucia Beatriz, Blain, Otilia Eva, Bravo, Mauro Nicolas, Sanchez, Nancy, Herrera Pesara, Luciana Martina, Moreno, Maria Eugenia, Sferco, Carlos Ariel, Huq, Umama, Ferdousi, Tamanna, Al-Mamun, Abdullah, Sultana, Sadia, Mahmud, Refoyez, Mahmud, Khalid, Sayeed, Fatema, Svirsky, Alexander, Sempertegui, Denisse, Negrete, Amalia, Teran, Araceli, Sadagurschi, Mariana, Popovic, Nusret, Karavdic, Kenan, Milisic, Emir, Jonuzi, Asmir, Mesic, Amira, Terzic, Sabina, Dendusic, Nejra, Biber, Elna, Sehic, Anesa, Zvizdic, Nada, Letic, Emina, Saracevic, Adna, Hamidovic, Ajla, Selak, Nejra, Horozic, Dzan, Hukic, Lamija, Muhic, Amila, Vanis, Nedim, Sokolovic, Emir, Sabic, Adnan, Becker, Karin, Novochadlo Klüppel, Elis, dos Santos Dias, André Iván Bradley, Agulham, Miguel Angelo, Bischoff, Cristiano, Sabbatini, Stella, Fernandes de Souza, Rachel, Souza Machado, Ana Beatriz, Werneck Raposo, Juliana, da Silva Augusto, Maria Lucia, Martins, Bianca M.R., de Souza Santos Ferreira, Mariana, Fernandes de Oliveira, Darli, Silva dos Santos, Carla, Ribeiro de Fernández y Alcázar, Fernanda, Alves Dutra da Silva, Érika, Furtado, Mariana, Tamada, Horácio, Silva Ferreira dos Santos, Marília, Lopes de Almeida, Thayná, Oliveira de Andrade, Susy, Gurgel do Amaral, Antonio Cipriano, Jr, Sartori Giovanoni, Lais, de Deus Passos Leles, Kamila, Corrêa Costa, Eduardo, Feldens, Leticia, Ferraz Schopf, Luciano, Soares de Fraga, José Carlos, Colombo de Holanda, Felipe, Brolin Santis Isolan, Paola Maria, Loyola Ferreira, Julia, Bruxel, Carla Luisa, Lopes Teixeira Ferdinando, Danielle, Zottis Barcelos, Fabricio, Baseggio, Natalia, Knorr Brenner, Nicole, Trindade Deyl, Rafael, Dure, Carolina, Nunes Kist, Iuri, Bueno Mazzuca, Rafael, Bueno Motter, Sarah, Ramos, Yna, Suzana Trein, Cristine, Rezende Rosa, Bianca, de Assis Silva, Murilo, Menin, Flavio Augusto, Semensato Carloni, Isabela Cristina, Norberto da Silva, Juliana Antinarelli, Gomes, Adriano Luis, Girão Tauffer, Mariana, Bassan Gonçalves, Paulo César, Nogueira Marques, Geraldo Magela, Moriya, Eliane, Labonia, Carla, Carrasco, Ana Lucia, Furtado Meyer, Karine, Farion-Aguiar, Luiz, Amado, Fernando, Antunes, Amanda, Silva, Elisângela, Telles, Leila, Almeida, Giovana, Belmino Gadelha, Aluísio Augusto, de Azevedo Belesa, Flavia, Gonçalves da Cunha, Jr, Acimar, Souza Barros, Beatriz, Zanellato, Josiane Bernartt, Guimarães, Patricia, Silva, Karina Ilheu da, Ribas, Bianca, Reuter, Cristina, Casado, Francis Tanise, Correa Leite, Mila Torii, Testoni, Daniela, Guinsburg, Ruth, de Campos Vieira Abib, Simone, Khodor Cury, Edson, Dornellas do Nascimento, Suely, Almeida Aguiar, Arthur, Melo Gallindo, Rodrigo, Gonçalves Borges, Carolina, Liu, Yang, Duote, Cai, Wang, Jinhu, Gao, Zhigang, Liang, Liang, Luo, Wenjuan, Zhao, Xiaoxia, Chen, Rui, Wang, Peng, Han, Yijiang, Huang, Ting, Donglai, Hu, Xiaodong, Guo, Junjie, Chen, Zhu, Libin, Wu, Guowei, Bao, Xiaozhou, Li, Haijing, Lv, Junying, Li, Zhongrong, Yong, Feng, Gao, Zhou Chong, Bai, Qiang, Tang, Weibing, Xie, Hua, Motee, Jethishka, Zhu, Jianming, Wen, Gang, Ruan, Weiwei, Li, Shungen, Chen, Lulu, Huang, Shungen, Lv, Zhibao, Lu, Jinjing, Huang, Liuming, Yu, Mengnan, Dajia, Wang, Bai, Yu Zuo, Rincon, Luis Carlos, Mancera, Juliana, Alzate Gallego, Edgar, Torres-Canchala, Laura, Silva Beltrán, Nathalia, Osorio Fory, Ghordana, Castaño Avila, Daniela, Forero Ladino, Angelica Maria, Gomez, Juanita, Jaramillo, Martha, Morales, Otto, Sanchez, Beatriz, Tinoco Guzmán, Nestor Julien, Castañeda Espinosa, Sergio, Prieto Vargas, Osbaldo, Pardo, Lina Maria, Toral, Eliana, Cáceres Aucatoma, Freud, Hinostroza, Daniel, Valencia, Santiago, Salinas, Vicente, Landivar Cino, Enrique, Ponce Fajardo, Gabriela Yulissa, Astudillo, Miguel, Garcia, Virginia, Muñoz, Guillermo, Verduga, Leonardo, Verduga, Ivan, Murillo, Ericka, Bucaram, Elena, Guayelema, Marisol, Marmol, Monica, Sanchez, Janina, Vergara, Carolina, Mena, Adriana, Velaña, Junior, Salazar, Karla, Lara, Sandra, Chiriboga, Elena, Silva, Julian, Gad, Dalia, Samy, Doaa, Elsadek, Menan Ahmed, Mohammed, Hanan Mahmoud, Abouheba, Mohamed, Ali, Karim Osamy, Rashwan, Hayssam, Fawzy, Omar Moustafa, Kamel, Tarek mohamed, Nemer, Rawan, Hassan, Mohamed Abada, Falah, Eyad Hassan, Abdelhady, Dina Sobhy, Zain, Mostafa, Ibrahim, Eman Abouzeid Abouzeid, Elsiraffy, Omar Ossama, Aboelela, Ahmed, Farag, Eman mohamed, Oshiba, Ahmed Mohamed, Emam, Omar Sameh, Attia, Alaa Mobarak, Laymouna, Moustafa A., Ghorab, Islam Abdelmonem, Mohammed, Mansour Mkayed, Soliman, Nourhan Akram, Ghaly, Khaled Abd elrahman, Sadek, Kareem, Elsherbiny, Mohamed, Saleh, Amr, Sheir, Hesham, Wafa, Tamer, Elmenam, Mohamed Abd, Abdelmaksoud, Sherif, Reda, Ahmed, Mansour, Islam, Elzohiri, Mohamed, Waseem, Basma, Elewaily, Mohamed, El-Ghazaly, Mohammed, Elhattab, Ahmad, Shalaby, Amr, Elsaied, Adham, Adawy, Ahmad, Sadek, Mirna, Ahmed, Mahmoud Abdelfattah, Herdan, Mohamed Omar, Elassall, Gena Mohamed Hamed, Mohammed, Azhar Arabi, Takrouney, Mohammed Hamada, Essa, Tarek Mohamed, Mahmoud, Ahmed Mokhtar, Saad, Alshaimaa M., Fouly, Mariam Albatoul Nageh, Ibrahim, Mahmoud abdelshakour, Nageh, Mohammad, Saad, Mahmoud M., Badr, Helmy, Fouda, Mohamed Fayez, Nofal, Ahmed Hassan, Almohamady, Hisham, Arafa, Mohamed Ahmed, Amad, Mohamed, Mansour, Mohamed Awad, O'Connor, Jennifer, O'Connor, Zachary, Anatole, Nzanzu, Nkunzimana, Elysé, Machemedze, Solomon, Dieudonné, Lemfuka, Appeadu-Mensah, William, Anyomih, Theophilus Teddy Kojo, Alhassan, Priscilla, Abantanga, Francis A., Michael, Vishal, Mary Koshy, Roshine, Raj, Ankit, Kumar, Vijay, PT, Sundeep, Prabhu, P Santosh, Vosoughi, Armin, Al-Mayoof, Ali Farooq, Fadhle, Muhamed Jassim, Joda, Ali Egab, Algabri, Hayder Nadhim Obaid, Abdelhamid, Sultan S., Al-Momani, Hashem M., Amarin, Marzouq, Zaghlol, Louay Y., Alsaadi, Nijmeh Nasser, Qwaider, Yasmeen Z., Qutishat, Hibah, Aliwisat, Ahmad Hasan, Arabiat, Esraa, Bsisu, Isam, Murshidi, Raghad M., Jabaiti, Mohammad S., Bataineh, Ziad A., Abuhayyeh, Husam Aldean, Quran, Thekraiat M. Al, Za'nouneh, Faris J. Abu, Alebbini, Mohanad Mutasem, Qudah, Hamzah Abullah, Hussein, Omar Ghazi, Murad, Amir M.I., Amarin, Justin Z., Suradi, Haya H., Alzraikat, Sayel H., Omari, Rand Y., Matour, Bashar M., Al-Halbouni, Layana, Zurikat, Rajai O., Yanis, Ahmad H., Hussein, Sara Al, Shoubaki, Ali, Ghanem, Waleed H., David, Kuria, Chitiavi, Soita Wycliffe, Mose, Moraa, Mugo, Robert, Ndungu, James, Mwai, Timothy, Shahbal, Swaleh, Malik, Janan, Chauhan, Nirav, Syovata, Francisa, Ochieng, Kevin, Omendo Liyenzero, Polycarp, Hussain, Syeda Ra'ana, Mugambi, Stanley, Ochieng, Roseline, Elkhazmi, Ebtesam Othman Abdulsalam, Khaled, Ala, Albozidi, Aya, Enbaya, Manal Ben, Elgammudi, Mala, Soula, Enas, Khalel, Wegden ibrahim almabrouk, Elhajjaji, Yasmine Ali, Alwaggaa, Nouriyah Ali, Ghayth, Sumayyah, Zreeg, Dafer abdulhakim .S., Tantush, Sara Abobaker, Bibas, Fatma, Layas, Tesneem, Sharif, Randa Alamen M, Aljadidi, Wesal Omar F. Saied, Tarek, Ahmed, Ahmed, Hazem, Essamilghi, Kamila Almabrouk Mohammed, Alfoghi, Mabroka, Abuhlega, Ma'aly A., Arrmali, Saddam, Abduljawad, Fatima Mousa, Alosta, Hasan Mustafa, Abuajaila, Abdulsalam, Abdelmutalib, Fakereldeen, Bashir, Fatma, Almengar, Inas, Annajjar, Mohammad hasan, Deyab, Abdelaziz, Elzowawi, Fathi, Krayem, Yousef, Drah, Weam, Meftah, Asma, Mohammed, Abobaker, Arrmalli, Lina Ali, Aljaboo, Hajir, Elayeb, Abdallah, Altomi, Mohamed, Altaweel, Ahmed, Tumi, Mohamed, Bazozi, Hana Milad, Shaklawoon, Aisha, Alglaib, Mohammed Meftah, Elkaloush, Abdullahn Abdousalam, Trainba, Sara, Swessi, Hisham, Alnaeri, Ali, Shnishah, Aya Essam, Mustufa, Hamassat, Gargum, Sondas Ali, Tarniba, Sara Ali, Shalluf, Hawa Ahmed, Shokri, Hajer Ali, Sarkaz, Taher L., Tababa, Osama, Elhadi, Ahmed, Naunova, Vesna Cvetanovska, Jovcheski, Laze, Kamilovski, Marjan, Gavrilovska-Brzanov, Aleksandra, Latiff, Zarina Abdul, Pauzi, Siti Farhan Moh, Osman, Marjmin, Lim, Felicia, Bakar, Ainal Huda Abu, Zaman, Azrina SK, Ishak, Shareena, Teo, Rufinah, Qi, Dr. Tammy Teoh Han, Othman, Mohd Yusran Bin, Zahari, Dato' Dr Zakaria bin, Hassan, Zulfitri bin Md, Shan, Cheah Hui, Lechmiannandan, Abhirrami, Tamaddun, Hafatin Fairos bt, Adanan, Mohd Fitri Shukri bin Mohamed, Abdullah, Mohd Yusof bin, Junyi, Wang, Nor, Mohd. Tarmizi Mohd, Noor, Wan Ruzaimie, Hassan, Mohd Razin bin, Dalek, Noor Fa'izatul Rahil Ambok, Hashim, Hidayah Hayati binti, Zarwawi, Ahmad Zulhisyam bin, Vellusamy, V Muthualhagi M, Yuen, Quah Soong, Kannessan, Hemasutha a/p, Ramli, Najua binti, Bujarimin, Ahmad Shafiee bin, Anntinea, Jessmine, Dass, Anthony, Khalid, Hazlina Mohd., Hanifah, Nur Atiqah binti Mohd, Jyun, Keily Wong Yue, Razak, Rahilah binti Abd, Naim, Nur Atifah binti Mohd, Hamzah, Siti Nur Aien binti Hamid, Vidal, Cristian R. Zalles, Bracho Blanchet, Eduardo, Dávila Perez, Roberto, Fernandez Portilla, Emilio, Villegas Silva, Raúl, Ibarra, Daniel, Calderon Moore, Antonio, Carrasco-Ortega, Cesar, Noguez Castillo, Monica, Herappe Mellado, Dorihela, Yanowsky Reyes, Guillermo, Gonzalez Cortez, Luis Fernando, Santana Ortiz, Rafael, Orozco Perez, Jamie, Corona C.Rivera, Jorge Román, Cardenas Ruiz Velasco, Juan Jose, Quiles Corona, Moises, Peña Padilla, Christian, Bobadilla Morales, Lucina, Corona Rivera, Alfredo, Rios Flores, Izabel Maryalexandra, Aranda Sánchez, Cristian Irela, Ambriz-González, Gabriela, Martínez Hernández Magro, Nestor, León Frutos, Francisco Javier, Cárdenas Barón, José de Jesús, González Ojeda, Alejandro, Yarza Fernández, Jessica, Porras, Juan Domingo, Aguirre-Lopez, Pastor, Sánchez Paredes, Vicente, Montalvo Marin, Arturo, Diaz Gomez, Jose Manuel, Caamal, Lorenzo Juvencio, Bulnes Mendizabal, David, Sanchez Valladares, Pablo, Garcia Martinez, Humberto, Adesanya, Opeoluwa, Olanrewaju, Moses, Adegboyega, Rilwan, Abdulraheem, Nurudeen, Aremo, Anuoluwapo, Dedeke, Florence, Chukwuemeka, Anyanwu Lofty-John, Mohammad, Mohammad Aminu, Lawalbarau, Abdullahi, Collins, Nwokoro, Ibukunolu, Ogundele, Shonubi, Amo, Ladipo-Ajayi, Oluwaseun, Elebute, Olumide Abiodun, Seyi-Olajide, Justina, Alakaloko, Felix, Ihediwa, George, Olayade, Kayode, Bode, Christopher, Ogundoyin, Olakayode, Olulana, Dare I., Egbuchulem, Ifeanyichukwu Kelvin, Kumolalo, Felix O., Ulasi, Ikechukwu, Ezomike, Uchechukwu Obiora, Ekenze, Sebastian Okwuchukwu, Nwankwo, Elochukwu Perpetua, Nwangwu, Emmanuel Ifeanyi, Chukwu, Isaac, Amah, Christopher Chim, Obianyo, Nene Elsie, Williams, Omolara, Osuoji, Roland Iheanyichukwu, Faboya, Omolara Moronkeji, Ajai, Olalekan Temitope, Abdulsalam, Moruf Adekunle, Agboola, Titiloye Hannah, Temilade, Bolarinwa Bolanle, Osazuwa, Maryrose, Salawu, Morayo Monsurat, Ejinkeonye, Eze Chukwuemeka, Yola, Mariya Mukhtar, Mairami, Amsa B., Otuneye, Adekunle T., Igoche, Matthias, Tanimola, Adebayo Gbenga, Ajao, Emmanuel Akinlabi, Agelebe, Efeturi, Olori, Samson, Mshelbwala, Philip Mari, Osagie, Olabisi, Oyinloye, Adewale, Abubakar, Auwal M, Oyebanji, Lateef, Shehu, Ibrahim, Cletus, Cyril, Bamanga, Ahmed, Suleiman, Faruk, Adamu, Sani, C.Nwosu, David, S.Alkali, Yahya, Jalo, Iliya, Rasaki, Aliu, T.Sambo, Yusuf, A.Mohammed, Kalakwa, M.Ballah, Abubakar, Modekwe, Victor, Ekwunife, Okechukwu Hyginus, Ezidiegwu, Ugochukwu S, Osuigwe, Andrew N, Ugwu, Jideofor O, Ugwunne, Chuka A, Akhter, Nadeem, Gondal, Mudassir Fayaz, Raza, Rafee, Chaudary, Ali Raza, Ali, Hassan, Nisar, Muhammad Umar, Jamal, Muhammad Umer, Pandit, Ghuri Shankar, Mumtaz, Uzma, Amjad, Muhammad Bin, Talat, Nabila, Rehman, Wajeeh ur, Saleem, Muhammad, Mirza, Muhammad Bilal, Hashim, Imran, Haider, Naveed, Hameed, Soban, Saleem, Ayesha, Dogar, Sohail, Sharif, Muhammad, Bashir, Muhammad Kashif, Naumeri, Fatima, Rani, Zarqa, Baniowda, Muath A.M., Ba'baa', Basheer, Hassan, Majd Yousef Mohammed, Darwish, Ammar, Sehwiel, Abrar Shaheen, Shehada, Mohammed, Balousha, Abrar ghassan, Ajrami, Yara, Alzamari, Ainaa Ata Mohammad, Yaghi, Bashar, Al-saleem, Hasan Subhi Hasan Abu, Farha, Mervat Sufian Abu, Abdelhafez, Mohammad Omar Mohammad, Anaya, Firas, Qadomi, Asef belal, Odi, Abd Al-Naser Bany, Assi, Muath Abdelrahem Fuad, Sharabati, Fadwa, Abueideh, Ahmad, Beshtawi, Doha mustafa saleh, Arafat, Hasan, Khatatba, Lara Zahi Adel, Abatli, Safa' Jamal, Al-Tammam, Hiba, Jaber, Dania, Kayed, Yara Imad Omar, Abumunshar, Ali Abdelhay, Misk, Rami Anwar, Alzeer, Asmahan Mohammad Suliman, Sharabati, Mutassem, Ghazzawi, Ihsan, Darras, Osama Majed, M.Qabaja, Mahmoud, Hajajreh, Ma'alem sameer, Samarah, Yasmeen Ahmad, Yaghi, Dua Hasan, Qunaibi, Moradallah Asad Fahmi, Mayaleh, Abdelrazzaq Abu, Joubeh, Sharehan, Ebeido, Annan, Adawi, Samer, Adawi, Ihda, Alqor, Mohammad Omar Ibrahim, Arar, Ahmad Samih, Awad, Hadeel, Abu-Nejmah, Fawzi, Shabana, Osaid Shaher, Alqarajeh, Firas, Alzughayyar, Tareq Z., Madieh, Jomana, Sbaih, Mahmoud Fuad, Alkareem, Raghad mohammad abdu, Lahlooh, Raghad abdullateef, Halabi, Yasmeen Adly, Baker, Wisam, Almusleh, Tasneem Fathi Hasan, Tahyneh, Abdulraheem Adnan Abdulraheem, Atatri, Yazid yousef mahmoud, Jamie, Najlaa Abu, Massry, Nasrallah Ashraf Al, Lubbad, Walaa, A.Nemer, Ayoub, Alser, Mohammed, Salha, Aya Azmi Shehda, Alnahhal, Khaled, Elmzyyen, Aya Mahmoud, Ghabayen, Amir Talat Sheda, Alamrain, Abdulwhhab Ayman Abu, Al-Shwaikh, Samar H., Elshaer, Omar Adly, Shaheen, Nureddin, Fares, Jehad, Dalloul, Hisham, Qawwash, Anas, Jayyab, Mustafa abu, Ashour, Dina Ayman, Shaheen, Ahmad Ashraf, Naim, Samy Rafat Ramadan, Shiha, Eman Abu, Dammagh, Nagham Mohammed Al, Almadhoun, Walaa, Al-Salhi, Ashraf Ayman, Hammato, Abdalkarim Yhya, Salim, Jamal Mohammed, Hasanain, Doaa Khalil, Alwadia, Soha Marwan Salem, Nassar, Ismail, Al-Attar, Hala M., Alshaikhkhalil, Haya Abdulnasser Ali, Jamie, Yasmin Mohammed Khalil Abu, Ashour, Yara shareef, Alijla, Sharif S., Tallaa, Mohamed Anwer El, Abuattaya, Adham Ashraf, Wishah, Bisan D.M., ALDIRAWI, MOHAMMED A.M., Darwish, Ahmed S, Alzerei, Sulaiman T., Wishah, Nidal, Alijla, Sharif, Garcia, Isidora, Diaz Echegaray, Marlene, Cañapataña Sahuanay, Veronica Raquel, Trigoso Mori, Fernando, Alvarado Zelada, Jackelyne, Salinas Barreto, Juan Jose, Rivera Altamirano, Porfirio, Torres Miranda, Cesar, Anicama Elias, Rocio, Rivera Alvarez, Julio, Vasquez Matos, Juan Pedro, Ayque Rosas, Fernando, Ledesma Peraza, Jesmarina, Gutarra Palomino, Andrea, Vega Centen, Stephany, Casquero, Victor, Ortiz Argomedo, María Rosa, Lapouble, Francisco, Llap Unchón, Genaro, Delgado Malaga, Florangel Patricia, Ortega Sotelo, Luis, Gamboa Kcomt, Segundo, Villalba Villalba, Araceli, Mendoza Leon, Nancy Rossana, Cardenas Alva, Loreley Raquel, Loo Neyra, Maria Susana, Alanguia Chipana, Cathy Lee, Torres Picón, Cintya Maria de Jesus, Huaytalla Quiroz, Natalia, Dominguez, Danny, Segura Calle, Carlos, Arauco, Jenny, Ormeño Calderón, Luis, Ghilardi Silva, Ximena, Fernandez Wilson, Miriam Daniela, Gutierrez Maldonado, Joan Elizabeth, Diaz Leon, Cesar, Berrocal Anaya, Waldo, Chavez Galvez, Patricia, Aguilar Gargurevich, Prince Pamela, Diaz Castañeda, Flor de Maria, Guisse, Carmen, Ramos Paredes, Erika, Apaza Leon, Jose Luis, Aguilar Aguilar, Faye, Ramirez De La Cruz, Raul, Flores Carbajal, Lenny, Mendoza Chiroque, Carlos, Sulca Cruzado, Gladys Johana, Tovar Gutierrez, Natalia, Sotelo Sanchez, Jennifer, Paz Soldan, Carolina, Hernández Córdova, Karina, Delgado Quinteros, Edgar Fernando, Brito Quevedo, Luz Mery, Mendoza Oviedo, Juan Jose, Samanez Obeso, Angel, Paredes Espinoza, Patricia, de Guzman, Johann, Yu, Raisa, Cosoreanu, Vlad, Ionescu, Sebastian, Mironescu, Aurel, Vida, Lucian, Papa, Adrian, Verdeata, Roxana, Gavrila, Bogdan, Muntean, Liviu, Lukac, Marija, Stojanovic, Miona, Toplicic, Djordje, Slavkovic, Milan, Slavkovi, Andjelka, Zivanovic, Dragoljub, Kostic, Ana, Raicevic, Maja, Nkuliza, Delphine, Sidler, Daniel, Vos, Corné de, Merwe, Elmarie vd, Tasker, David, Khamag, Omar, Rengura, Cecilia, Siyotula, Thozama, Jooma, Uzair, Delft, Dirk von, Arnold, Marion, Mangray, Hansraj, Harilal, Shamaman, Madziba, Sanele, Wijekoon, Naveen, Gamage, Tharanga, Bright, Benedict Paul, Abdulrahman, Alaa, Mohammed, Ola Ahmed Abdulmjeed, Salah, Mohammed, Ajwa, Ahmad Elian Abu, Morjan, Mohammed, Batal, Mohammad Mohannad, Faks, Vivian, Mouti, Mohamad Bassel, Assi, Ahmadfateh, Al-Mouakeh, Ahmad, Tarabishi, Ahmad Sankari, Aljarad, Ziad, Alhamid, Aos, Khorana, Jiraporn, Poocharoen, Wannisa, Liukitithara, Sirima, Sriniworn, Anan, Nuntasunti, Wasun, Ngerncham, Monawat, Phannua, Ratiyaporn, Thaiwatcharamas, Kanokrat, Tanming, Patchareeporn, Sahnoun, Lassaad, Kchiche, Nahla, Abdelmoumen, Roua, Eroğlu, Egemen, Ozen, Mehmet Ali, Cömert, Hatice Sonay Yalçın, İmamoğlu, Mustafa, Sarıhan, Haluk, Kader, Şebnem, Mutlu, Mehmet, Aslan, Yakup, Beşir, Ahmet, Geze, Şükran, Çekiç, Bahanur, Yalcinkaya, Ali, Sönmez, Kaan, Karabulut, Ramazan, Türkyılmaz, Zafer, Şeref, Kıvanç, Altın, Merve, Aykut, Merve, Akan, M.Eren, Erdem, Melisa, Ergenekon, Ebru, Türkyılmaz, Canan, Keleş, Elif, Canözer, Ali, Yeniay, Aslı Öztürk, Eren, Elif, Cesur, İlknur Banlı, Özçelik, Zerrin, Kurt, Gökmen, Mert, Mustafa Kurthan, Kaya, Hatice, Çelik, Müge, Karakus, Suleyman Cuneyt, Erturk, Nazile, Suzen, Alev, Hakan, Nilay, Akova, Fatih, Pasaoglu, Mehmet, Eshkabilov, Shukurali, Yuldashev, Rustam Z., Abdunomonovich, Dekhkonboev Avazjon, Muslimovich, Aliev Makhmudjan, Patel, Azad, Kapihya, Chisengo, Ensar, Nicholas, Nataraja, Ramesh M, Sivasubramaniam, Mithila, Jones, Matthew, Teague, Warwick, Tanny, Sharman Tan, Thomas, Gordon, Roberts, Kiera, Venkatraman, Soundappan Sannappa, Till, Holger, Pigeolet, Manon, Dassonville, Martine, Shikha, Anas, Win, Win Sabai Phyu, Ahmad, Zahidah Adlynee Haji, Meloche-Dumas, Léamarie, Caouette-Laberge, Louise, St-Vil, Dickens, Aspirot, Ann, Piché, Nelson, Joharifard, Shahrzad, Safa, Nadia, Laberge, Jean-Martin, Emil, Sherif, Puligandla, Pramod, Shaw, Kenneth, Wissanji, Hussein, Duggan, Eileen, Guadagno, Elena, Puentes, Maria Consuelo, Leal, Paola Osses, Mendez Benavente, Carolina, Rygl, Michal, Trojanová, Barbora, Berková, Klára, Racková, Tereza, Planka, Ladislav, Škvařil, Jan, Štichhauer, Radek, Sabti, Shahad, Macdonald, Alex, Bouhadiba, Nordeen, Kufeji, Dorothy, Pardy, Caroline, Mccluney, Simon, Keshtgar, Alireza, Roberts, Rebecca, Rhodes, Hannah, Burns, Kate, Garrett-Cox, Robin, Ford, Kat, Cornwall, Hannah, Ravi, Krithi, Arthur, Felicity, Losty, Paul, Lander, Tony, Jester, Ingo, Arul, Suren, Gee, Oliver, Soccorso, Giampiero, Singh, Michael, Pachl, Max, Martin, Benjamin, Alzubair, Afnan, Kelay, Arun, Sutcliffe, Jonathan, Middleton, Thomas, Thomas, Amy Hughes, Kurian, Merina, Cameron, Fraser, Sivaraj, Jayaram, Thomas, Mark C, Rex, Dean, Jones, Ceri, Bradshaw, Kate, Bonnard, Arnaud, Delforge, Xavier, Duchesne, Camille, Gall, Caroline Le, Defert, Coralie, Laraqui Hossini, Samia, Guerin, Florent, Hery, Géraldine, Fouquet-Languillat, Virginie, Kohaut, Jules, Broch, Aline, Blanc, Thomas, Harper, Luke, Delefortrie, Thomas, Ballouhey, Quentin, Fourcade, Laurent, Grosos, Céline, Parmentier, Benoit, Levard, Guillaume, Grella, Maria Giovanna, Renaux Petel, Mariette, Grynberg, Lucie, Abbo, Olivier, Mouttalib, Sofia, Juricic, Mélodie, Scalabre, Aurelien, Haraux, Elodie, Rissmann, Anke, Krause, Hardy, Goebel, Peter, Patzer, Ludwig, Rolle, Udo, Schmedding, Andrea, Antunez-Mora, Alexandra, Tillig, Bernd, Bismarck, Sylvester von, Barbosa, Patricia Reis, Knorr, Christian, Stark, Domitille, Brunero, Marco, Avolio, Luigi, Manni, Francesco, Molinelli, Matilde, Guazzotti, Marinella, Raffaele, Alessandro, Romano, Piero Giovanni, Cavaiuolo, Silvia, Parigi, Gian Battista, Juhasz, Laszlo, Rieth, Anna, Strumila, Arunas, Dagilytė, Rūta, Liubsys, Arunas, Gurskas, Pranas, Malcius, Dalius, Mikneviciute, Agne, Vinskaite, Asta, Barauskas, Vidmantas, Vierboom, Liam, Hall, Timothy, Beasley, Spencer, Goddard, Lucy, Stringer, Mark, Weeratunga, Naveen, Adams, Stephen, Cama, Jitoko, Wong, Marilyn, Jayaratnam, Sridharan, Kukkady, Askar, Samarakkody, Udaya, Gerus, Sylwester, Patkowski, Dariusz, Wolny, Agnieszka, Koszutski, Tomasz, Tobor, Szymon, Osowicka, Marta, Czauderna, Piotr, Wyrzykowski, Dariusz, Garnier, Hanna, Anzelewicz, Stefan, Marta, Osowicka, Knurowska, Agata, Weiszewsk, Alicja, Grabowski, Andrzej, Korlacki, Wojciech, Pasierbek, Michal, Wolak, Przemyslaw, Piotrowska, Aneta, Roszkiewicz, Anna, Kalicińsk, Piotr, Trypens, Agata, Kowalewsk, Grzegorz, Sigalet, David, Alsaied, Amer, Ali, Mansour, Alsaggaf, Ameen, Ghallab, Alaa, Owiwi, Yazeed, Zeinelabdeen, Ali, Fayez, Mohamed, Atta, Ahmed, Zidan, Mazen, Radwan, Asaad saleh, Shalaby, Hanin, Abdelbaqi, Reem, Alattas, Khalid, Kano, Yar, Sindi, Omar, Alshehri, Abdullah, Altokhais, Tariq, Alturki, Fahad, Almosaibli, Mohammad, Krisanova, Dasha, Abbas, Wisam, Yang, Hee-Beom, Kim, Hyun-Young, Youn, Joong Kee, Chung, Jae Hee, Cho, Seok Hyeon, Hwang, In ji, Lee, Ju yeon, Song, Eung song, Arboleda, Jenny, Ruiz de Temiño Bravo, Mercedes, Siles Hinojosa, Alexander, García, Miriam, Casal Beloy, Isabel, Oliu San Miguel, Detlef, Molina Vazquez, Maria Elena, Alonso, Verónica, Sanchez, Alberto, Gomez, Oscar, Carrillo, Isabel, Wester, Tomas, Mesas Burgos, Carmen, Salö, Martin, Omling, Erik, Rudolfson, Niclas, Granéli, Christina, Arnadóttir, Helena, Grottling, Emma, Abrahamsson, Kate, Gatzinsky, Vladimir, Dellenmark Blom, Michaela, Borbonet, Daniel, Puglia, Paul, Jimenez Morejon, Vinicio, Acuna, Gaston, Moraes, Mario, Chan, Jonathan, Brahmamdam, Pavan, Tom, Alan, Sherer, Karen, Gonzales, Brandy, Cunningham, Aaron, Krishnaswami, Sanjay, Baertschiger, Reto, Leech, Mary, Williams, Regan, Camp, Lauren, Gosain, Ankush, Mora, Maria, Lyttle, Bailey D., Chang, Jeremy, McColl Makepeace, Lydia, Fowler, Kathryn L, Mansfield, Sara, Hodgman, Erica, Amaechi, Chukwubinyelum, Beres, Alana, Pernik, Mark N., Dosselman, Luke J., Almasri, Murad, Jain, Sunil, Modi, Varun, Fernandez Ferrer, Marianelly, Coon, John, Gonzalez, Joann, Honhar, Medhavi, Ruzgar, Nensi, Coghill, Griffin, Ullrich, Sarah, Cheung, Maija, Løfberg, Katrine, Greenberg, Jodie, Davenport, Kate, Gadepalli, Samir, Fox, Sarah, Johnson, Stephanie, Pilkington, Mercedes, Hamilton, April, Lin, Nicole, Sola, Juan, Yao, Yang, Davis, Jenna Kylene, Langer, Monica, Vacek, Jonathan, Abdullah, Fizan, Khlevner, Julie, Middlesworth, William, Levitt, Marc, Ahmad, Hira, Siddiqui, Sabina M, Bowder, Alex, Derks, Terry, Amoabin, Afua Amoabin, Pinar, Brooke, Owusu-Sekyere, Frank, Saousen, Benmanseur, Naidoo, Rasika, Karamustafic, Azra, Oliveira, Danielle Paula de, Motter, Sarah Bueno, Andrade, Jerhy, Šafus, Antonín, Langley, Jason, Wilke, Alexandra, Deya, Corazone, Murtadi, Habib Mansour, Berzanskis, Mindaugas, Calistus, Nwachukwu, Ajiboye, Olalekan S., Felix, Michael, Olabisi, Osagie O, Erçin, Seçil, Muradi, Teymursha, Burks, Stephen S., Lerma, Sergio, Jacobson, Jillian, Calancea, Calin, Valerio-Vazquez, Rafael, Sikwete, Guigui, Sekyere, Owusu, Mbonisweni, Akhona, Syed, Shahnoor, Hyeon, Cho Seok, Pajouhandeh, Fatemeh, and Kunfah, Sheba Mary Pognaa

Published
2021
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9. A novel and simple machine learning algorithm for preoperative diagnosis of acute appendicitis in children

Author

Aydın, Emrah (ORCID 0000-0001-7776-9684 & YÖK ID 32059); Eroğlu, Egemen, Türkmen, İnan Utku; Namlı, Gözde; Özturk, Çiğdem; Esen, Ayşe B.; Eray, Y. Nur; Akova, Fatih, School of Medicine, Aydın, Emrah (ORCID 0000-0001-7776-9684 & YÖK ID 32059); Eroğlu, Egemen, Türkmen, İnan Utku; Namlı, Gözde; Özturk, Çiğdem; Esen, Ayşe B.; Eray, Y. Nur; Akova, Fatih, and School of Medicine

Abstract

Introduction: there is a tendency toward nonoperative management of appendicitis resulting in an increasing need for preoperative diagnosis and classification. For medical purposes, simple conceptual decision-making models that can learn are widely used. Decision trees are reliable and effective techniques which provide high classification accuracy. We tested if we could detect appendicitis and differentiate uncomplicated from complicated cases using machine learning algorithms. Materials and methods: we analyzed all cases admitted between 2010 and 2016 that fell into the following categories: healthy controls (Group 1); sham controls (Group 2); sham disease (Group 3), and acute abdomen (Group 4). The latter group was further divided into four groups: false laparotomy; uncomplicated appendicitis; complicated appendicitis without abscess, and complicated appendicitis with abscess. Patients with comorbidities and whose complete blood count and/or pathology results were lacking were excluded. Data were collected for demographics, preoperative blood analysis, and postoperative diagnosis. Various machine learning algorithms were applied to detect appendicitis patients. Results: there were 7244 patients with a mean age of 6.84 +/- 5.31 years, of whom 82.3% (5960/7244) were male. Most algorithms tested, especially linear methods, provided similar performance measures. We preferred the decision tree model due to its easier interpretability. With this algorithm, we detected appendicitis patients with 93.97% area under the curve (AUC), 94.69% accuracy, 93.55% sensitivity, and 96.55% specificity, and uncomplicated appendicitis with 79.47% AUC, 70.83% accuracy, 66.81% sensitivity, and 81.88% specificity. Conclusions: machine learning is a novel approach to prevent unnecessary operations and decrease the burden of appendicitis both for patients and health systems., NA

Published
2020

12. Reevaluation of recurrence mechanisms after Nissen fundoplication

Author

Özen, Mehmet Ali, Uzuner, Selçuk, Gökçe, Selim, Tekin, Mehmet, Eroğlu, Egemen, Gündoğdu, Gökhan, and Tıp Fakültesi

Subjects
Gastroözofageal Reflü, Orofaringeal Semp- Tomlar, Recurrence, Nörolojik Bozukluk, Nüks, Gastroesophageal Reflux, Orophary- Ngeal Symptoms, Fundoplication, Fundoplikasyon, Neurologically Impairment
Abstract

Amaç: Nissen fundoplikasyon, gastroözofageal reflü hastalığı (GÖRH) tedavisinde en sık uygulanan cerrahi yöntem olmakla birlikte özellikle nörolojik engelli hastalarda nüks gelişimi sıktır. Manşonun anatomik olarak bozulması klasik tanımlanan şeklidir. Nüks oluşumu için öngörülen risk faktörleri olgu- ların birçoğunda var olmakla birlikte, başarısızlığın patolojisini net olarak açıklayamamaktadır. Çalışmamızda, fundoplikasyon sonrası başarısızlık mekanizmalarını analiz etmeyi amaçladık. Yöntem: Çalışmaya, Ocak 2011 ile Şubat 2014 arasında fundoplikasyon yapılan GÖRH’li çocuklar dahil edildi. Ameliyat sonrası devam eden reflü semptomları, nüks gastroözofageal reflü hastalığı (nGÖRH) olarak kabul edildi. Cinsiyet, yaş, gelişme geriliği, nörolojik durum, hiatus hernisi, skolyoz, ameliyat yöntemleri, gastrostomi ve orofaringeal semptomlar ile nüks oluşumu arasındaki ilişki araştırıldı. Değişkenler lojistik regresyon analizi ile incelendi. Bulgular: Çalışmaya 67 çocuk (erkek 40, kız 27) dahil edildi. Ortalama ameliyat yaşı 57,10±52,22 ay, takip süresi 19,64±7,75 ay idi. On altı (%23,8) çocukta nüks reflü saptandı. Nüks olguların baryumlu calışmalarında yalnızca 1 olguda (%6,2) fundoplikasyon manşonu bozulmuş idi. Manşonu sağlam olan 15 hastadan 10’una endoskopik inceleme yapılabildi. Nüks nedeni olarak, 7 olguda gevşek manşon, 3 olguda aralıklı manşon gevşemesi aktiviteleri gözlendi. Gevşek manşon ve aralıklı gevşemenin, sırasıyla ciddi yutma bozukluğu ve öğürme gibi orofarengeal semptomlar ile ilişkili oldugu saptandı. Sonuç: Nörolojik engeli olan bir kısım hastada anatomik olarak sağlam fundoplikasyon yapıya rağmen, alt özofagus sfinkter relaksasyonlarının devam etmesinin veya gevşek manşon yapısının, hastalarda nüks nedeni olabilecegini varsaymaktayız. Ayrıca bu endoskopik bulguların farklı orofarengeal semp- tomlar ile ilişkisi altta yatan baska bir kompleks nüks mekanizmasını düşündürmektedir. Orofarengeal semptomlar ameliyat öncesinde nüks gelişim riskini öngörmede yararlı olabilir., Objective: Nissen fundoplication is the most frequently performed surgery for the gastroesophageal reflux disease (GERD), however recurrence is frequent in neurologically impaired patients. Anatomic deformation of the fundoplication wrap is the classically defined presentation. The putative risk factors exist in most of cases and but they are unable to define the pathology of failure. We aimed to analyze failure mechanisms after fundoplication. Method: Children with GERD who had undergone fundoplication between January 2011 and February 2014 were included in the study. Ongoing reflux symptoms after surgery were considered as recurrence of gastroesophageal reflux disease (rGERD). Correlation between development of disease recurrence and gender, age, failure to thrive, neurological status, hiatus hernia, scoliosis, surgical methods, gastrostomy and oropharyngeal symptoms was investigated. Variables were studied by logistic regression analysis. P

Published
2019

16. Does voiding cystourethrogram exclude posterior urethral valves in late presenting cases?

Author

Özen, Mehmet Ali; Taşdemir, Mehmet (ORCID 0000-0002-5579-6339 & YÖK ID 175867); Gündoğdu, Gökhan; Bilge, İlmay (ORCID 0000-0002-4852-989X & YÖK ID 198907); Eroğlu, Egemen, Büyükünal, Cenk, School of Medicine, Department of Pediatric Surgery; Department of Pediatric Nephrology, Özen, Mehmet Ali; Taşdemir, Mehmet (ORCID 0000-0002-5579-6339 & YÖK ID 175867); Gündoğdu, Gökhan; Bilge, İlmay (ORCID 0000-0002-4852-989X & YÖK ID 198907); Eroğlu, Egemen, Büyükünal, Cenk, School of Medicine, and Department of Pediatric Surgery; Department of Pediatric Nephrology

Abstract

Introduction: delayed presentation of posterior urethral valves (PUVs) is a rare condition. Presentation and diagnosis of the patients with late PUVs are challenging. Voiding cystourethrogram (VCUG) is mainly practiced. In this study, we aimed to evaluate the children with late-presented PUVs, and the reliability of VCUG in this group. Materials and methods: between January 2003 and December 2017 records of patients who were diagnosed with late-presented PUVs were analyzed. Delayed presentation of PUV was defined as patients who were diagnosed and treated after infancy. Cases were examined in terms of age at diagnosis, presenting symptoms, urinalysis, urinary ultrasound, urodynamic studies, VCUG, and dimercaptosuccinic acid scintigraphy findings. Postoperative follow-up conditions were also assessed. Results: seventeen boys were diagnosed with late-presented PUVs (mean age was 7.35 years). The most common symptoms at presentation were frequency (58.8%), day and nighttime incontinence (47%), and febrile urinary infection (41%). PUV was noted by VCUG in 10 patients alone. The classical sign of dilated posterior urethra was detected in 9 patients. The 10th patient had posterior urethral irregularity. Urethra could not be evaluated due to unsuccessful voiding in one patient. Six patients had normally appearing urethra on VCUG. Reflux was detected in nine (52.9%) patients. Conclusion: late-presented PUVs may be missed on VCUG. Whether a PUV might be present is crucial in boys with a history of recurrent urinary infection, persistent reflux, and repetitive daytime incontinence. Based on our results, we conclude that cystoscopic examination should be preferred for those cases to diagnose PUVs regardless of VCUG results., NA

Published
2019

18. Is there a unique symptom in lower urinary tract dysfunction in children?

Author

Özen, Mehmet A., Taşdemir, Mehmet, Aygün, Murat S., Necef, Işıl, Aydın, Emrah, Bilge, Ilmay, and Eroğlu, Egemen

Subjects
URINARY organs, MEDICAL personnel, SYMPTOMS, URINATION disorders, OVERACTIVE bladder, VESICO-ureteral reflux, RHEUMATIC heart disease
Abstract

Objectives: Lower urinary tract symptoms (LUTS), particularly urgency, incontinence and intermittency are common in children and it is suggested that the specific symptoms may be used for definite diagnosis for LUT dysfunction (LUTD). This study was performed to investigate the relationship between each LUTD and its associated symptoms, using uroflowmetry/electromyography (UF/EMG) as a diagnostic tool. Methods: Each patient was categorized into one of four LUT conditions which were overactive bladder (OAB), dysfunctional voiding (DV), underactive bladder and primary bladder neck dysfunction (PBND), according to UF/EMG results. Patients' complaints and findings were documented by using voiding dysfunction symptom score, bladder diary, urine analysis and ultrasonography. In addition, a detailed history of bowel habits (including use of Rome III criteria) was obtained. Results: There were 189 children of which 106 were female. The OAB was the largest group including 91 patients, followed by the DV group which had 61 patients. The symptoms specific to any LUTD group were constipation and hesitancy (P <.05). Hesitancy was present in 89.4% with PBND and constipation was present in 78.6% of patients with DV. None of other symptoms were able to differentiate any LUTD group from the other. Conclusions: While certain symptoms are often presumed by clinicians to imply specific diagnoses, the main outcome of this study is that there is a generally weak correlation between the specificity of symptoms and LUTD. Symptoms‐based approach may lead to misdiagnosis in LUTD. Thus, it may be essential to focus on the underlying pathologies and UF/EMG test may help this. [ABSTRACT FROM AUTHOR]

Published
2021
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26. Does Voiding Cystourethrogram Exclude Posterior Urethral Valves in Late Presenting Cases?

Author

Özen, Mehmet Ali, Taşdemir, Mehmet, Gündoğdu, Gökhan, Bilge, Ilmay, Büyükünal, Cenk, and Eroğlu, Egemen

Subjects
URETHRA, URETHRAL obstruction, INFECTION, DIAGNOSTIC imaging, URETHRA abnormalities, BOYS, URINATION disorders, URETHRA surgery, RESEARCH evaluation, URETHRA stricture, URINARY tract infections, URINATION, DISEASE relapse, RETROSPECTIVE studies
Abstract

Introduction:  Delayed presentation of posterior urethral valves (PUVs) is a rare condition. Presentation and diagnosis of the patients with late PUVs are challenging. Voiding cystourethrogram (VCUG) is mainly practiced. In this study, we aimed to evaluate the children with late-presented PUVs, and the reliability of VCUG in this group.Materials and Methods:  Between January 2003 and December 2017 records of patients who were diagnosed with late-presented PUVs were analyzed. Delayed presentation of PUV was defined as patients who were diagnosed and treated after infancy. Cases were examined in terms of age at diagnosis, presenting symptoms, urinalysis, urinary ultrasound, urodynamic studies, VCUG, and dimercaptosuccinic acid scintigraphy findings. Postoperative follow-up conditions were also assessed.Results:  Seventeen boys were diagnosed with late-presented PUVs (mean age was 7.35 years). The most common symptoms at presentation were frequency (58.8%), day and nighttime incontinence (47%), and febrile urinary infection (41%). PUV was noted by VCUG in 10 patients alone. The classical sign of dilated posterior urethra was detected in 9 patients. The 10th patient had posterior urethral irregularity. Urethra could not be evaluated due to unsuccessful voiding in one patient. Six patients had normally appearing urethra on VCUG. Reflux was detected in nine (52.9%) patients.Conclusion:  Late-presented PUVs may be missed on VCUG. Whether a PUV might be present is crucial in boys with a history of recurrent urinary infection, persistent reflux, and repetitive daytime incontinence. Based on our results, we conclude that cystoscopic examination should be preferred for those cases to diagnose PUVs regardless of VCUG results. [ABSTRACT FROM AUTHOR]

Published
2019
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27. Complication of newborn circumcision: meatal stenosis or meatal web?

Author

Özen, Mehmet Ali; Eroğlu, Egemen, Gündoğdu, Gökhan; Taşdemir, Mehmet, Koç University Hospital, School of Medicine, Department of Pediatric Surgery, Özen, Mehmet Ali; Eroğlu, Egemen, Gündoğdu, Gökhan; Taşdemir, Mehmet, Koç University Hospital, School of Medicine, and Department of Pediatric Surgery

Abstract

Introduction: Meatal stenosis (MS) is a known complication of newborn circumcision. Symptoms are usually masked in young kids with a diaper. Deflation of urinary stream, dysuria, urinary frequency, and incontinence are the most common reported symptoms. Diagnosis of MS is still controversial. A narrow pinpoint urethral meatus is the current accepted diagnostic criteria. Objective: In our practice, we observed that our cases do not overlap to the classic definition and presentation of MS. In this study, we presented our cases and aimed to share our observations. Materials and methods: Records of children who had meatoplasty between 2014 with 2016 were analyzed retrospectively. Only children with MS who had had newborn circumcision performed in our clinic were included in the study. Over 500 newborn circumcisions are performed per year in our clinic using the Gomco Clamp technique. Age at diagnosis, presenting complaints, penile anomalies including urethral meatus configuration, urinary symptoms, operation methods, and postoperative follow-up were gathered. Results: A total of 13 boys who were circumcised in the newborn period had undergone meatoplasty with the diagnosis of MS. The mean age at the time of meatoplasty was 52.5 +/- 17.9 (range 37e93 months). All children were examined before and during the circumcision. There were no associated penile anomalies, including MS. The only presenting complaint was upward deflation of urinary stream instead of other lower urinary tract symptoms. Although the appearance of the meatus was pinpoint in all cases (Figure); it was easy to calibrate with an 8-10 Fr feeding tube. There was no stenosis, but a ventral web was detected. Meato-plasty with removal of this web was performed under general anesthesia. Two sutures were applied at 5 and 7 o'clock with 7/ 0 PDS. Mean postoperative follow-up time was 16.9 +/- 7.5 months. Children were pleased with direction of urinary stream. Discussion: Both the diagnosis and morphological defi, NA

Published
2017

28. Maternal stres yenidoğan nöroblastomu nedenlerinden birisi midir?

Author

EROĞLU, Egemen, ŞARMAN, Gülnihal, DAYANIKLI, Pınar, DANİŞMEND, Nur, KEBUDİ, Rejin, and YILDIZ, İnci

Abstract

Introduction and Aim: Previous studies have investigated the association between several perinatal factors and the risk of newborn neuroblastoma, but none of these studies have investigated the effect of maternal emotional experiences. The aim of this study is to attract attention to the possible relation between the fear induced maternal stress and newborn neuroblastoma. Material and Methods: The files of three newborn neuroblastoma patients were analyzed and the mothers were questioned to investigate the presence of emotional stress during the pregnancy period. Results: Diagnosis of all babies was discovered in the first two weeks of life. The babies were normal during the prenatal sonographic examinations. Just one month prior to delivery, all mothers experienced severe stress. Two of the mothers were involved in a car accident, and the other experienced severe distress because she was involved in an accident where her son was hurt. In two cases the tumor was surgically removed. These infants are disease free two and three years after the surgery. Complete removal was not successful in the third case, and chemotherapy had to be performed. Four years after chemotherapy, the patient was diagnosed with myelodysplastic syndrome and then secondary leukemia and is now undergoing treatment. Conclusion: Because of the rarity of neonatal neuroblastomas, it is clear that multicenter studies are necessary to understand the epidemiologic background and to develop optimal treatment protocols., Giriş ve Amaç: Daha önce yapılan çalışmalarda çeşitli perinatal faktörlerle yenidoğan nöroblastom riski arasındaki bağlantı araştırılmış, ancak bu çalışmaların hiçbirisi annenin duygusal deneyimlerinin etkisini araştırmamıştır. Bu çalışmanın amacı annenin çok korkmasına bağlı oluşan stresle yenidoğan nöroblastomu arasındaki olası bağlantıya dikkat çekmektir. Gereç ve yöntem: Yenidoğan nöroblastomlu üç olgunun dosyaları incelenmiş, annelerinin perinatolojik dönemde yaşadıkları duygusal deneyimler sorgulanmıştır. Bulgular: Bebeklerin hepsinin tanısı ilk iki hafta içerisinde konulmuştur. Perinatolojik takipleri tamamen normal olan hastaların anneleri son gebelik ayında ciddi bir korkma anı yaşayarak strese maruz kalmışlardır, iki anne trafik kazasına uğramış, diğer annenin ise çocuğu bisikletle annenin gözü önünde kaza geçirmiştir. İki hastada tümör tamamen çıkarılabilmiştir. Bu iki hasta ameliyattan sonra ikinci ve dördüncü yıllarında sorunsuz takip edilmektedir. Üçüncü hastada cerrahi olarak tam çıkarlamamış, ve kemoterapi uygulanmak zorunda kalınmıştır. Kemoterapiden dört yıl sonra myelodisplastik sendrome ve ikincil lösemi tanıları konulmuştur. Hasta halen tedavi altındadır. Sonuç: Çok nadir tümörler olduklarından etkin kemoterapi protokollerini oluşturmak ve epidemiyolojik tabanı saptayabilmek için daha çok merkezli çalışmalara ihtiyaç duyulmaktadır.

Published
2014

29. Kortikosteroidli Kremlerin Yenidoğan Sünneti Sonrası Penil Yapışıklıkların Tedavisinde Yeri Var Mıdır?

Author

EROĞLU, Egemen and OKTAR, Tayfun

Abstract

Obejective and Aim: The objective ofthis study is to analyze the effectiveness of corticosteroid creams in treatment ofmucosal preputial adhesions after neonatal circumcision. Material and Methods: The treatment modalities ofpreputial adhesions in children, who have been circumcised in the newbom period in our hospital by the Gomco Clamp technique, were reviewed and the results after using corticosteroid creams were analysed. The patients with skin bridges were not included in the study. Results: 181 patients with preputial adhesions were admitted in the last three years. Topical steroid was used for three weeks in 41 of them. Steroid creams were not effective in any of the patients, and the adhesions were simply lysed after EMLA erearn anesthesia. .. Conclusion: Although commonly seen after circumcision, it is stil/ not clear how to approach and how to treat penile adehsions when necessary. Topical steroid application does not have a role in treatment ofmucosal adhesions after circumcision., Giriş ve Amaç: Bu çalışmanın amacı, kortikosteroidli kremlerin yenidoğan sünnetinden sonra gelişebilen mukoza/ prepusyum yapışık/ık/arındaki etkinliğini araştırmaktır. Gereç ve yöntem: Hastanemize yenidoğan sünneti sonrası penil yapışıklıkla başvuran olguların dosyaları incelenmiş, kortikosteroidli krem kullanılanlarda etkinlik araştırılmıştır. Cilt köprüsü olan çocuklar çalışmaya dahil edilmemiştir. Bulgular: Son üç yıl içerisinde 181 hasta prepusyal yapışıklıka başvurmuştur. 41 tanesinde üç hafta boyunca topikal steroid uygulanmıştır. Steroidli kremler hiçbir yapışıklıkta etkili olamamıştır, yapışıklık/ar EMLA krem ile uygulanan fokal anestezi yardımıyla elle açılmıştır. Tartışma: Sünnetten sonra oldukça sık görülmelerine rağmen, gerektiği taktirde penil yapışıklık/ara nasıl yak/aşılacağı ve nasıl tedavi edilmesi gerektiği net değildir. Topikal steroid kullanımının sünnet sonrası mukoza! yapışıklık/arın tedavisinde rolü yoktur.

Published
2014

33. Obstrüksiyona karşı mesane boşaltımının düz kas fizyolojisinde oluşturduğu değişiklikler ve nitrik oksit donörü nitroprussitin mesane düz kas aktivitesine etkisi

Author

Eroğlu, Egemen, Danişmend, Nur, and Çocuk Cerrahisi Ana Bilim Dalı

Subjects
Pediatric Surgery, Çocuk Cerrahisi
Abstract

ÖZET Amaç: Bu çalışmadaki amacımız mesane düz kasının parsiyel obstrüksiyon karşısındaki fizyolojik değişikliklerini incelemek, sistometrik çalışmalarla obstrüksiyon öncesi ve sonrası farklılıkları değerlendirmek ve NO donörü nitroprussid'in detrusor üzerindeki etkisini araştırmaktır. Gereç ve Yöntem: Çalışmada toplam 12 adet erişkin tavşan kullanılmış, 6 tanesi 3 hafta süreyle parsiyel mesane çıkışı obstrüksiyonuna maruz bırakılmış, 6 tanesi ise kontrol grubunu oluşturmuştur. Obstrüksiyonlu tavşanlara, obstrüksiyonlu oldukları 3 hafta öncesinde ve sonrasında sistometri yapılarak değerleri karşılaştırılmıştır. Üç hafta sonunda mesaneden alınan dokuların bir kısmı histolojik değerlendirilmiş, bir kısmı ise deneysel çalışmada kullanılmıştır. Deneysel çalışma için hazırlanan detrusor şeritlerinin elektriksel uyarı ve asetilkolin uyarısıyla kasılmaları kayıt edilmiş, asetilkolin ve neostigmin ile kasılmaları sağlanmış dokuların, NO vericisi olan nitroprussid karşısındaki gevşeme değerleri ölçülerek, kontrol grubundaki değerlerle karşılaştırılmıştır. Detrusor şeritlerinin ayrıca artan ağırlık uygulamaları karşısında boy uzamaları ölçülmüş ve elastik limitleri saptanmıştır. Sonuçlar: Dokuların histolojik değerlendirilmesinde obstrüksiyonlu grupta detrusor kasında hipertrofı, duvar içindeki damarlarda hiperemi ve seyrek mononükleer hücre infiltrasyonu bulunmuştur. Sistometrik değerlendirme sonucunda obstrüksiyonlu tavşanların mesane kapasitelerinde %32.5 kadar azalma saptanmış, ortalama kompliyans değerleri kontrol grubunda 4.3±1.8 iken, obstrüksiyonlu grupta 1.6±0.3 hesaplanmıştır. Detrusor şerit çalışmalarında, kasılma için gerekli eşik voltaj değerleri obstrüksiyon grubunda 57.5'dan 93.3V değerine çıkmış, elektriksel uyarıya yanıt artmış, asetilkolin uyarısında ise belirgin bir fark gözlenmemiştir. Kasılma sağlanmış detrusor 32üzerine nitroprussidin herhangi bir etkisi olmadığı saptanmıştır. Artan ağırlık uygulamaları ile saptanan elastik limit değerinin, obstrüksiyonlu grupta daha yüksek olduğu bulunmuştur. Tartışma: Obsrüksiyona maruz kalan detrusor kendisini obstrüksiyona karşı adapte etmeye çalışmakta, bunun için de hipertrofiye uğramaktadır. Bu adaptasyon süresi içerisinde mesane kapasitesinde azalma, hipertrofiye uğramış detrusor elastisite yeteneğinde kaybolma, dolayısıyla daha küçük hacimlerde daha yüksek basınçlara ulaşılmasına sebep olmaktadır, yani mesanenin kompliyansı düşmektedir. Obstrüksiyon nedeniyle oluşan nörojenik hasar, eşik voltaj değerindeki yükselmeyle gösterilebilmekte ve uyarının başlayabilmesi için daha yüksek voltaj değerleri gerekmektedir. NO donörü nitroprussid, detrusor düz kası üzerinde gevşetme etkisine sahip değildir. 33 36

Published
2001

36. Hepatobiliary mucinous cystadenoma in a child

Author

Şenyüz, Osman Faruk, primary, Numan, Firuzan, additional, Eroğlu, Egemen, additional, Sarımurat, Nüvit, additional, Bozkurt, Pervin, additional, Cantaşdemir, Murat, additional, and Dervişoğlu, Sergülen, additional

Published
2004
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37. Meconium/Stool and Urinary Patterns of Healthy Newborns.

Author

Kayiran, Sinan Mahir, EroĞlu, Egemen, Kayiran, Petek, Sazak, Soner, and Gürakan, Berkan

Subjects
*ACADEMIC medical centers, *CHI-squared test, *DEFECATION, *FISHER exact test, *NEWBORN screening, *STATISTICS, *U-statistics, *URINATION, *DATA analysis, *DATA analysis software, *DESCRIPTIVE statistics
Abstract

Objective: The time of passage of the newborn’s first meconium/stool is an indicator of health and is used to screen for normal gastrointestinal tract function. Most newborns urinate after birth, and this is an indication of normal renal function. The aim of this study is to investigate the meconium/stool and urinary patterns of healthy neonates, and to determine whether they correlate with delivery mode, birth weight, feeding method and its frequency. Patients and Methods: Newborns with a gestational age of ≥ 34 week delivered by normal vaginal delivery (NVD) or cesarean section (CS) were included. The newborns were fed either breast milk exclusively or a combination of breast milk and formula. The frequency of meconium/stool and urine passage and the delivery type, birth weight, and feeding method and its frequency were recorded throughout their hospital stay. Results: A total of 1095 newborns were included. By the first 24 h after birth, 986 (90%) newborns had passed their first meconium or stool and 1084 (99%) newborns had passed their first urine. The mean number of meconium/stool and urine passages was higher in neonates delivered by CS. The mean number of meconium/stools within the first 24 h was higher in newborns fed breast milk exclusively. Combination-fed newborns and newborns with a lower birth weight had a higher mean number of urine passages. The number of meconium passages in the first 24 h was significantly lower in newborns weighing < 2500 g. Conclusion: The mode of delivery, birth weight, and feeding method and its frequency may influence meconium/stool and urinary patterns in newborns. [ABSTRACT FROM AUTHOR]

Published
2012
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39. A novel and simple machine learning algorithm for preoperative diagnosis of acute appendicitis in children

Author

Egemen Eroğlu, Gozde Namli, Emrah Aydin, Ayse B. Esen, Cigdem Ozturk, İnan Utku Türkmen, Yasar N. Eray, Fatih Akova, Aydın, Emrah (ORCID 0000-0001-7776-9684 & YÖK ID 32059), Eroğlu, Egemen, Türkmen, İnan Utku, Namlı, Gözde, Özturk, Çiğdem, Esen, Ayşe B., Eray, Y. Nur, Akova, Fatih, School of Medicine, and Tıp Fakültesi

Subjects
Male, Artificial intelligence, medicine.medical_specialty, Nonoperative management, Artifcial Intelligence, Pediatrics, Surgery, medicine.medical_treatment, Decision tree, Diagnosis, Differential, Machine Learning, 03 medical and health sciences, 0302 clinical medicine, Nonoperative Management, 030225 pediatrics, Laparotomy, Machine learning, Pediatric surgery, medicine, Appendectomy, Humans, Abscess, Child, Children, medicine.diagnostic_test, business.industry, Area under the curve, Complete blood count, General Medicine, Institutional review board, medicine.disease, Appendicitis, Acute abdomen, Child, Preschool, Pediatrics, Perinatology and Child Health, Acute Disease, Preoperative Period, 030211 gastroenterology & hepatology, Female, medicine.symptom, business, Algorithm, Algorithms
Abstract

Introduction: there is a tendency toward nonoperative management of appendicitis resulting in an increasing need for preoperative diagnosis and classification. For medical purposes, simple conceptual decision-making models that can learn are widely used. Decision trees are reliable and effective techniques which provide high classification accuracy. We tested if we could detect appendicitis and differentiate uncomplicated from complicated cases using machine learning algorithms. Materials and methods: we analyzed all cases admitted between 2010 and 2016 that fell into the following categories: healthy controls (Group 1); sham controls (Group 2); sham disease (Group 3), and acute abdomen (Group 4). The latter group was further divided into four groups: false laparotomy; uncomplicated appendicitis; complicated appendicitis without abscess, and complicated appendicitis with abscess. Patients with comorbidities and whose complete blood count and/or pathology results were lacking were excluded. Data were collected for demographics, preoperative blood analysis, and postoperative diagnosis. Various machine learning algorithms were applied to detect appendicitis patients. Results: there were 7244 patients with a mean age of 6.84 +/- 5.31 years, of whom 82.3% (5960/7244) were male. Most algorithms tested, especially linear methods, provided similar performance measures. We preferred the decision tree model due to its easier interpretability. With this algorithm, we detected appendicitis patients with 93.97% area under the curve (AUC), 94.69% accuracy, 93.55% sensitivity, and 96.55% specificity, and uncomplicated appendicitis with 79.47% AUC, 70.83% accuracy, 66.81% sensitivity, and 81.88% specificity. Conclusions: machine learning is a novel approach to prevent unnecessary operations and decrease the burden of appendicitis both for patients and health systems., NA

Published
2020

40. Complication of newborn circumcision: meatal stenosis or meatal web?

Author

Gokhan Gundogdu, Egemen Eroğlu, Mehmet Ali Özen, Mehmet Taşdemir, Özen, Mehmet Ali, Eroğlu, Egemen, Gündoğdu, Gökhan, Taşdemir, Mehmet, Koç University Hospital, School of Medicine, and Department of Pediatric Surgery

Subjects
Male, medicine.medical_specialty, Meatus, Pediatrics, Urology and nephrology, Urology, Urinary system, 030232 urology & nephrology, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, Lower urinary tract symptoms, 030225 pediatrics, Medicine, Dysuria, Humans, Child, Feeding tube, Retrospective Studies, Urethral Stricture, business.industry, Newborn, Circumcision, Stenosis, Web, Infant, Newborn, medicine.disease, Meatal stenosis, Surgery, Circumcision, Male, Child, Preschool, Pediatrics, Perinatology and Child Health, medicine.symptom, business, Complication
Abstract

Introduction: Meatal stenosis (MS) is a known complication of newborn circumcision. Symptoms are usually masked in young kids with a diaper. Deflation of urinary stream, dysuria, urinary frequency, and incontinence are the most common reported symptoms. Diagnosis of MS is still controversial. A narrow pinpoint urethral meatus is the current accepted diagnostic criteria. Objective: In our practice, we observed that our cases do not overlap to the classic definition and presentation of MS. In this study, we presented our cases and aimed to share our observations. Materials and methods: Records of children who had meatoplasty between 2014 with 2016 were analyzed retrospectively. Only children with MS who had had newborn circumcision performed in our clinic were included in the study. Over 500 newborn circumcisions are performed per year in our clinic using the Gomco Clamp technique. Age at diagnosis, presenting complaints, penile anomalies including urethral meatus configuration, urinary symptoms, operation methods, and postoperative follow-up were gathered. Results: A total of 13 boys who were circumcised in the newborn period had undergone meatoplasty with the diagnosis of MS. The mean age at the time of meatoplasty was 52.5 +/- 17.9 (range 37e93 months). All children were examined before and during the circumcision. There were no associated penile anomalies, including MS. The only presenting complaint was upward deflation of urinary stream instead of other lower urinary tract symptoms. Although the appearance of the meatus was pinpoint in all cases (Figure); it was easy to calibrate with an 8-10 Fr feeding tube. There was no stenosis, but a ventral web was detected. Meato-plasty with removal of this web was performed under general anesthesia. Two sutures were applied at 5 and 7 o'clock with 7/ 0 PDS. Mean postoperative follow-up time was 16.9 +/- 7.5 months. Children were pleased with direction of urinary stream. Discussion: Both the diagnosis and morphological definition of MS have some controversies. To our knowledge, there is no similar reported study with pinpoint appearance and normal calibration of the meatus. There was no stenosis in any of them. Unlike classical MS presentations, upward deflation of urinary stream resulting from ventral web was a single presenting complaint. Conclusions: Upward deflation of urinary stream can develop after neonatal circumcision because of a meatal web without stenosis, and can be cured easily with meatoplasty. Instead of 'meatal stenosis', 'meatal web' may be a more appropriate term to explain the pathology in these patients., NA

Published
2017

41. Effectiveness of extracorporeal shock wave lithotripsy on intrahepatic biliary calculi developing after choledochal cyst surgery: A case report.

Author

Şenyüz OF, Gülşen F, Gökhan O, Emre Ş, and Eroğlu E

Subjects
Adolescent, Bile Ducts, Intrahepatic, Choledochal Cyst surgery, Gallstones etiology, Humans, Liver surgery, Male, Postoperative Complications etiology, Anastomosis, Roux-en-Y adverse effects, Gallstones therapy, Jejunostomy adverse effects, Lithotripsy methods, Postoperative Complications therapy
Abstract

The development of intra- and extrahepatic bile duct stones has been reported as one of the most serious complications after choledochal cyst excision with biliary-enteric reconstruction through Roux-en-Y hepaticojejunostomy (HJ). Here, we report our experience with extracorporeal shock wave lithotripsy (ESWL) in a case of giant intrahepatic stones developing after choledochal cyst surgery. ESWL is an excellent therapeutic modality for large intrahepatic biliary calculi, and after dilating the HJ anastomosis percutaneously, it can be offered as first-line therapy to these patients.

Published
2015
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