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5. Congenital Heart Defects and Outcome in a Large Cohort of Down Syndrome: A Single-Center Experience from Turkey.

Author

Alkaya, Dilek Uludağ, Öztürk, Birol, Ülker, Aylin Yüksel, Bozlak, Serdar, Öztürk, Esra, Dedeoğlu, Reyhan, Eroğlu, Ayşe Güler, Öztunç, Funda, and Tüysüz, Beyhan

Subjects
PATENT ductus arteriosus, DOWN syndrome, TETRALOGY of Fallot, CONGENITAL heart disease, MANN Whitney U Test, DESCRIPTIVE statistics, CHI-squared test, KAPLAN-Meier estimator, PROGRESSION-free survival, DATA analysis software, VENTRICULAR septal defects, DISEASE risk factors
Abstract

Objective: Congenital heart defects occur in approximately 50% of children with Down syndrome and they contribute considerably to morbidity and mortality. The aim of this study is to investigate the prevalence, classification, and survival of congenital heart defects in Down syndrome. Materials and Methods: About 1731 Down syndrome patients who underwent echocardiography between 1986 and 2022 were evaluated. The median follow-up duration was 8.7 years (range 1-35.8 years). Congenital heart defect was grouped as cyanotic and acyanotic. Results: Among the 1731 patients, 52.1% had congenital heart defects. Congenital heart defect was significantly more common in females than males. The most common cardiac defect was ventricular septal defect (35%), followed by atrial septal defect (31.8%), atrioventricular septal defect (23.4%), tetralogy of Fallot (5%), and patent ductus arteriosus (3.6%). In the follow-up, 43.2% of atrial septal defect, 17.8% of ventricular septal defect, and a total of 20% of congenital heart defects were closed spontaneously. About 34.4% of congenital heart defect was corrected by cardiac surgery/intervention. Five-year survival rate was 97.4% in patients without congenital heart defects, whereas it was 95.6% in mild congenital heart defects and 86.1% in moderate to severe congenital heart defects. There was no relationship between consanguinity, parental age, maternal disease, folic acid supplementation before/during pregnancy, gestational age, birth weight, and congenital heart defects. Neuromotor development was similar in patients with and without congenital heart defects. Conclusion: We demonstrated that almost half of the patients had congenital heart defects; ventricular septal defect was the most common congenital heart defect type. This study is valuable in terms of the largest single-center study describing the classification, prognostic factors, and survival of Down syndrome patients with congenital heart defect from Turkey. [ABSTRACT FROM AUTHOR]

Published
2023
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7. Evaluation of left ventricular function and myocardial deformation in children with beta‐thalassemia major by real‐time three‐dimensional (four‐dimensional) and speckle tracking echocardiography

Author

Eroğlu, Ayşe Güler, primary, Uluğ, Nujin, additional, Karakaş, Hasan, additional, Yüksel, Esra Karabıyık, additional, Akyel, Nazlı Gülsüm, additional, Çığ, Gülnaz, additional, Adaletli, İbrahim, additional, Özdemir, Gül Nihal, additional, Türkkan, Emine, additional, and Celkan, Tülin Tiraje, additional

Published
2022
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8. Early and Mid-Term Follow-Up Results After Transcatheter Closure of Secundum Atrial Septal Defect.

Author

Kılınç, Burcu, Eroğlu, Ayşe Güler, and Saltık, İrfan Levent

Subjects
*CARDIAC catheterization, *CARDIAC surgery, *ECHOCARDIOGRAPHY, *RETROSPECTIVE studies, *QUANTITATIVE research, *SURGERY, *PATIENTS, *SURGICAL complications, *ATRIAL septal defects, *TREATMENT effectiveness, *DOPPLER echocardiography, *T-test (Statistics), *DESCRIPTIVE statistics, *SOCIODEMOGRAPHIC factors, *THERAPEUTIC complications, *LONGITUDINAL method, *EVALUATION
Abstract

Objective: Transcatheter secundum type atrial septal defect closure is an alternative to surgical closure in many cases when conditions are appropriate. In this study, the demographic data and follow-up results of patients with secundum atrial septal defect undergoing transcatheter closure were discussed. Materials and Methods: Data of patients who underwent transcatheter closure of secundum atrial septal defect between 2004 and 2017 were investigated retrospectively. Gender, age at intervention, defect size, procedure duration, fluoroscopy time, periprocedural complications, residual shunt existence, and early and mid-term follow-up results were collected. Results: A total of 179 patients [41% males; 10% adults, median age: 8.1 years (1.3-58.6); weight: 28 kg (11-90)] were admitted to catheterization for atrial septal defect closure and their median atrial septal defect size was 13 mm (6-30); 74 (41%) patients had a large atrial septal defect (≥12 mm). Suitable defects for closure were observed in 165 of 179 patients. The procedural success rate was 95.7%. No death was observed; however, minor complications occurred in 3 patients during the procedure (1.6%). The rate of residual shunt after 1 year was 1.3%, and all shunts were mild. After a median follow-up of 2.8 years (range, 6 months to 13.6 years), delayed major complications such as death, cardiac erosion, and infective endocarditis were not experienced. The delayed minor complication was supraventricular extrasystole in 1 patient. Conclusion: Transcatheter atrial septal defect closure is safe in children and adults with a minimal rate of periprocedural and delayed complications. It has a favorable early and mid-term outcome in our study, especially with no death or major complications. [ABSTRACT FROM AUTHOR]

Published
2022
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18. Cardiovascular side effects related with use of synthetic cannabinoids 'bonzai' : two case reports

Author

Atik, Sezen Ugan, Dedeoğlu, Reyhan, Varol, Fatih, Çam, Halit, Eroğlu, Ayşe Güler, and Saltık, Levent

Subjects
digestive, oral, and skin physiology, lipids (amino acids, peptides, and proteins), Case Report
Abstract

Information about the effects of synthetic cannabinoids “bonzai” on the cardiovascular system is limited. In this article, two patients in whom different cardiological side effects were observed following use of synthetic cannabinoids ‘bonzai’ were presented.

Published
2015

19. Kendiliğinden gelişen pnömomediyastinum olgusu

Author

ŞAHİN, Sezgin, MASOOM, Mohammed Ajmal, EROĞLU, Ayşe Güler, and TAŞTAN, Yücel

Subjects
Cilt altı amfizemi,göğüs ağrısı,göğüs filmi,Hamman belirtisi,kendiliğinden pnömomediyastinum,nefes darlığı, Chest film,chest pain,dyspnea,Hamman’s sign,spontaneous pneumomediyastinum,subcutaneous emphysema
Abstract

Spontaneous pneumomediastinum is the presence of free air in the mediastinum without any identifiable etiology like trauma or invasive procedure Hower thoracic pain is the major complaint The symptom triad of thoracic pain dyspnea and subcutaneous emphysema is typical We present a 13 year old young male presenting to the emergency room with a complaint of thoracic pain Physical examination was unremarkable except for Hamman rsquo;s sign Examinations including chest x ray revealed pneumomediastinum In this case when evaluating thoracic pain we aimed to emphasize the importance of pyhsical examination particulary the cardiac auscultation Turk Arch Ped 2013; 48: 336 8, Kendiliğinden pnömomediyastinum travma ve girişim öyküsü olmayan bir kişide mediyastende serbest hava bulunmasıdır Göğüs ağrısı ile birlikte nefes darlığı ve cilt altı amfizemi tipik bulgulardır Acil polikliniğimize göğüs ağrısı yakınmasıyla getirilen 13 yaşında erkek hastada Hamman belirtisinin saptanması üzerine pnömomediyastinum düşünülen ve toraks grafisiyle doğrulanan bir olguyu sunmak istedik Amacımız göğüs ağrısıyla gelen hastalarda dikkatli bir dinleme ve dolayısıyla ayrıntılı fizik muayenenin önemini vurgulamaktır Türk Ped Arfl 2013; 48: 336 8

Published
2014

20. Bebeklik döneminde siyanotik kalp hastalığı nedeniyle açık kalp cerrahisi uygulanmış ergenlerde kendilik algısı ve yaşam niteliği

Author

Yıldız, Cenk Eray, Zahmacıoğlu, Oğuzhan, Koca, Bülent, Oktay, Veysel, Gökalp, Selman, Eroğlu, Ayşe Güler, Çetin, Gürkan, and Öztunç, Funda

Subjects
Health Care Sciences and Services, Sağlık Bilimleri ve Hizmetleri, Doğuştan kalp hastalığı,ergen,kendilik algısı profili,siyanoz,yaşam niteliği
Abstract

Aim: To assess the quality of life of the teenage patients who had undergone open heart surgery because of cyanotic heart disease during their infancy together with their parents and to compare their self perception to that of the physically healthy control group Material and Method: This study includes 53 patients who had undergone operation for cyanotic congenital heart disease in İstanbul University Institute of Cardiology between 1989 and 1994 The relatives and the patients were informed with a consent form approved by İstanbul University Cerrahpaşa Medical Faculty Clinical Studies Ethics Commitee Decree no D 005 Date: 11 10 2009 Group 1 was the healthy control group 15 patients median age: 19 years 8 months Group 2 included patients with single ventricle who had undergone Fontan procedure 20 patients median age: 19 years 6 months; 10 of them had tricuspid atresia 5 of them had pulmonary atresia with intact ventricular septum 3 of them had double inlet left ventricle 1 of them had double outlet right ventricle 1 of them had ventricular septal defect and pulmonary atresia group 3 included patients who had undergone operation for congenital cyanotic heart disease 33 patients median age: 19 years 2 months; 18 of them had transposition of the great arteries 10 of them had tetralogy of Fallot 2 of them had complete atrioventricular canal defect and pulmonary stenosis 2 of them had double outlet right ventricle 1 of them had pentalogy of Fallot In this study the quality of life and self perception inventories were used The quality of life inventory was completed by patients healthy adolescents and their parents seperately The self perception inventory was completed only by the patients and healthy adolescents The comparison of age and self perception scores between the groups was carried out with unidirectional analysis of variance ANOVA and the multicomparisons with LSD Least Significant Difference Since the quality of life variable did not have a normal distribution the comparions were carried out with Kruskal Wallis nonparametric ANOVA test and the multicomparisons were carried out with Dunn 39;s test Results: There was not a significant difference between the groups in terms of age and sex In the quality of life scale QOLS for the replies to related questions a significant difference was determined between the groups The replies of group 2 and 3 about quality of life of both the children and the parents were far more negative when compared to those of the control group When the groups were compared via multiple comparison tests there was no significant difference between group 2 and 3 The replies of the parents regarding their children 39;s quality of life were statistically more negative than those of their children p lt;0 001 Within the self perception scale there were significant differences in terms of social acceptance behaviours in relationships and general self perception p=0 03 p=0 03 and p=0 01; repectively between group 1 and 3 The most significant difference that was detected between group 1 and 2 was about behaviours in relationships p=0 04 Conclusions: With the help of developing technology and surgical experience many complex cyanotic heart diseases are treated successfully and most patients reach puberty However the responses for quality of life and self perception paremeters of this group of patients are more negative than those of the control group Therefore these adolescents and especially their parents may need psychosocial support Turk Arch Ped 2011; 46: 212 9, Amaç: Bebeklik döneminde siyanotik kalp hastalığı nedeniyle açık kalp ameliyatı geçiren hastaların, ergenlik dönemindeki yaşam niteliği ölçeğini ebeveynleriyle beraber değerlendirmek ve kendilik algılarıyla birlikte fiziksel olarak sağlıklı kontrol grubuyla karşılaştırmaktır. Gereç ve Yöntem: Bu çalışmaya 1989-1994 yılları arasında İstanbul Üniversitesi Kardiyoloji Enstitüsü’nde doğuştan siyanotik kalp hastalığı nedeniyle ameliyat edilmiş 53 hasta alındı. İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Klinik Araştırmalar Etik Kurulu’ndan (Karar numarası: D-005, Tarih: 10-11-2009) onay alınarak, hasta ve yakınları onam formuyla bilgilendirildi. Grup 1 fiziksel olarak sağlıklı kontrol grubu (15 kişi, ort. yaş: 19 yıl, 8 ay), grup 2 Fontan ameliyatı uygulanan tek ventriküllü hastalar (20 hasta, ort. yaş: 19 yıl, 6 ay; 10’unda triküspit atrezisi, beşinde intakt ventriküler septumlu pulmoner atrezi, üçünde çift girişli sol ventrikül, birinde çift çıkışlı sağ ventrikül, birinde ventriküler septal defekt ve pulmoner atrezi), grup 3 ise diğer doğuştan siyanotik kalp hastalığı nedeniyle ameliyat olmuş hastalardı (33 hasta, ort. yaş: 19 yıl, 2 ay; 18’inde büyük arterlerin transpozisyonu, 10’unda Fallot tetralojisi, ikisinde tam atriyoventriküler kanal defekti, pulmoner darlık, ikisinde çift çıkışlı sağ ventrikül, birinde Fallot pentalojisi). Çalışmada yaşam niteliği ve kendilik algısı ölçekleri kullanıldı. Yaşam niteliği ölçeğini hasta ve fiziksel olarak sağlıklı ergenler ile ebeveynleri ayrı ayrı doldurdu. Kendilik algısı ölçeğini sadece hasta ve fiziksel olarak sağlıklı ergenler doldurdu. Yaş ve kendilik algısı puanlarının gruplar arasındaki karşılaştırmaları tek yönlü varyans analizi (ANOVA) ile; çoklu karşılaştırılmaları ise LSD (Least Significant Difference) ile yapıldı. Yaşam niteliği değişkeni normal dağılıma sahip olmadığı için karşılaştırmalar Kruskal-Wallis nonparametrik ANOVA testi ile, çoklu karşılaştırmalar ise Dunn testi ile yapıldı. Bulgular: Yaş ve cinsiyet açısından gruplar arasında anlamlı fark yoktu. Yaşam niteliği ölçeğinde, ilgili sorulara verilen yanıtlarda gruplar arasında ileri derecede anlamlı fark saptandı. Grup 2 ve 3 için yaşam niteliğine yönelik yanıtlar hem ebeveynlerde hem de çocuklarda kontrol grubuna göre çok daha olumsuzdu. Çoklu karşılaştırma testi ile gruplar kıyaslandığında, grup 2 ve 3 arasında anlamlı fark saptanmadı. Ebeveynlerin çocuklarının yaşam niteliği ile ilişkili yanıtları, çocuklarınınkinden istatistiksel olarak daha olumsuzdu (p

Published
2014

21. Ani kalp durmasının nadir bir nedeni: Katekolaminerjik polimorfik ventriküler taşikardi.

Author

Atik, Sezen Ugan, Alp, Firuze Erbek, Dedeoğlu, Reyhan, Koka, Aida, Öztunç, Funda, and Eroğlu, Ayşe Güler

Subjects
AMIODARONE, CALCIUM, CARDIAC arrest, CARDIOPULMONARY resuscitation, DOBUTAMINE, GENE expression, GENETIC polymorphisms, HYPOTENSION, INTENSIVE care units, GENETIC mutation, NORADRENALINE, SYNCOPE, VENTRICULAR fibrillation, GENETIC testing, VENTRICULAR tachycardia, TERMINATION of treatment, GENETIC carriers, GENETICS, THERAPEUTICS
Abstract

Copyright of Türk Pediatri Arşivi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018
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24. Primer mitral kapak prolapsusu olan çocuklarda QT dispersiyonu ve ventriküler aritmiler.

Author

İmamoğlu, Ebru Yalın and Eroğlu, Ayşe Güler

Abstract

Aim: To investigate ventricular arrhythmias in children with primary mitral valve prolapse and to evaluate its relation with QT length, QT dispersion, autonomic function tests and heart rate variability measurements. Material and Methods: Fourty two children with mitral valve prolapse and 32 healthy children were enrolled into the study. Twelve-lead electrocardiograms, autonomic function tests, echocardiography and 24-hour rhythm Holter tests were performed. Electrocardiograms were magnified digitally. The QT length was corrected according to heart rate. The patients were grouped according to the number of premature ventricular contractions and presence of complex ventricular arhythmia in the 24-hour rhythm Holter monitor test. Heart rate variability measurements were calculated automatically from the 24-hour rhythm Holter monitor test. Orthostatic hypotension and resting heart rate were used as autonomic function tests. Results: The mean age was 13.9±3.3 years in the patient group and 14.6±3.1 years in the control group (p>0.05). Thirty four of the patients (81%) were female and eight (19%) were male. Twenty five of the control subjects (78%) were female and seven (22%) were male. The QT dispersion and heart rate corrected QT interval were found to be significantly increased in the children with primary mitral valve prolapse when compared with the control group (56±16 ms vs. 43±11 ms, p=0.001; 426±25 ms vs. 407±26 ms, p=0.002, respectively). In 24-hour rhythm Holter monitor tests, ventricular arrhythmias were found in 21 out of 42 patients (50%) and 6 out of 32 control subjects (18.8%) (p=0.006). QT dispersion was found to be significantly increased in patients with premature ventricular contractions > 10/day and/or complex ventricular arrhythmias compared to the control group without ventricular premature beats (p=0.002). There was no significant difference in autonomic function tests and heart rate variability measurements between the patient and control groups. Conclusions: The noted increase in QT dispersion may be a useful indicator for the clinician in the evaluation of impending ventricular arrhythmias in children with primary mitral valve prolapse. [ABSTRACT FROM AUTHOR]

Published
2016
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25. Akut romatizmal ateş tanısında güncelleme: 2015 Jones ölçütleri.

Author

Eroğlu, Ayşe Güler

Subjects
*RHEUMATIC fever diagnosis, *PENICILLIN G, *BLOOD sedimentation, *ECHOCARDIOGRAPHY, *CARDIOMYOPATHIES, *RHEUMATIC fever, *RHEUMATIC heart disease, *JOINT pain, *ANTIBIOTIC prophylaxis, *THERAPEUTICS
Abstract

In the final Jones criteria, different diagnostic criteria were established for the diagnosis of acute rheumatic fever for low risk and moderate-high risk populations. Turkey was found to be compatible with moderate-high risk populations as a result of regional screenings performed in terms of acute rheumatic fever and rheumatic heart disease. The changes in the diagnostic criteria for low-risk populations include subclinical carditis found on echocardiogram as a major criterion in addition to carditis found clinically and a body temperature of 38.5°C and above as a minor criterion. In moderate-high risk populations including Turkey, subclinical carditis found on echocardiogram in addition to clinical carditis is used as a major criterion as a new amendment. In addition, aseptic monoarthritis and polyarthralgia are used as major criteria in addition to migratory arthritis and monoarhtralgia is used as a minor criterion among joint findings. However, differentiation of subclinical carditis from physiological valve regurgitation found in healthy individuals and exclusion of other diseases involving joints when aseptic monoarthritis and polyarthralgia are used as major criteria are very important. In addition, a body temperature of 38°C and above and an erythrocyte sedimentation rate of 30 mm/h and above have been accepted as minor criteria. The diagnostic criteria for the first attack have not been changed; three minor findings have been accepted in presence of previous sterptococcal infection in addition to the old cirteria for recurrent attacks. In the final Jones criteria, it has been recommended that patients who do not fully meet the diagnostic criteria of acute rheumatic fever should be treated as acute rheumatic fever if another diagnosis is not considered and should be followed up with benzathine penicilin prophylaxis for 12 months. It has been decided that these patients be evaluated 12 months later and a decision for continuation or discontinuation of prophylaxis should be made. In countries where the disease is prevalent, it is very important for physicians to make an accurate diagnosis of acute rheumatic fever with their own logic and assessment in addition to the criteria proposed. [ABSTRACT FROM AUTHOR]

Published
2016
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26. Tam düzeltme ameliyatı yapılan fallot tetralojili hastalarda ameliyat tekniğinin sağ ventrikül diyastolik fonksiyonlarına etkisi

Author

Eroğlu, Ayşe Güler, Sarıoğlu, Ayşe, and Diğer

Subjects
Çocuk Sağlığı ve Hastalıkları, Child Health and Diseases
Abstract

Çocukluk çağında en sık görülen doğumsal siyanotik kalp hastalığı olan Fallot tetralojisinin cerrahi tedavisinde değişik ameliyat teknikleri kullanılmaktadır. Son yıllarda Doppler ekokardiyografi ile kateter laboratuvarına girmeden ve karmaşık hesaplamalar yapmadan çeşitli kalp hastalıklarında ventriküllerin diyastolik fonksiyonları çalışılmaya başlanmıştır. Çalışmamızda ameliyat tekniğinin klinik bulgular, ventriküllerin büyüklükleri, sağ ventrikül diyastolik fonksiyonları üzerine etkisini aydınlatmak amacıyla transanüler yama kullanılan hastalar ile, transatriyal düzeltme yapılan veya infindübüler yama kullanılan hastalar klinik özellikleri, 2-B ekokardiyografik ölçümleri, sağ ventrikül diyastolik fonksiyonları açısından, birbirleri ile ve sağlıklı çocuklarla karşılaştırıldı. Hastalar ayrıca sağ ventrikül restriksiyonunun bir bulgusu olarak kabul edilen pulmoner arterde geç diyastolde öne akımın artıp artmadığına göre 2 gruba ayrılarak klinik özellikleri, 2-B ekokardiyografik ölçümleri ve sağ ventrikül diyastolik fonksiyonları karşılaştırıldı. Diğer taraftan hasta gruplarında solunumun sağ ventrikül diyastolik fonksiyonları üzerine etkisi araştırıldı.Transanüler yama kullanılan hastaların hepsinde pulmoner yetersizlik üfürümü duyulurken transtatriyal düzeltme yapılan veya infindübüler yama kullanılan hastaların %64'ünde duyuldu. Telegrafide kalp-toraks indeksi transanüler yama kullanılan hastalarda anlamlı olarak artmıştı. Elektrokardiyografide sağ dal bloğu saptanması açısından gruplar arasından farklılık bulunmadı.2-B ekokardiyografik incelemede transanüler yama kullanılan hastalarda sağ ventrikül volümü, boyu ve triküspit anülüsünün normal çocuklara göre artmış olduğunu, buna karşılık transatriyal düzeltme yapılan veya infindübüler yama kullanılan grupta ise sağ ventrikül volümü ve triküspit anülüsünün normal çocuklardan farklı olmadığı tespit edildi.Transanüler yama kullanılan hastalarda triküspit pulsed Doppler özelliklerinin incelenmesinde sağ ventrikül relaksasyon bozukluğunu gösterir şekilde erken hızlı doluşun azaldığı ve atriyal sistole bağlı geç doluşun arttığı; E/A hız, E/A hız-zaman integrali ve E/toplam hız-zaman integralinin azaldığı, A/toplam hız-zaman integralinin arttığı gösterildi. Transatriyal düzeltme yapılan veya infindübüler yama kullanılan hastalarda ise relaksasyon bozukluğunu gösteren bulgulardan sadece E/A hızın azaldığı, A/toplam hız-zaman integralinin arttığı saptandı. Diğer taraftan transanüler yama kullanılan hastalarda E/A hız ve E/toplam hız-zaman integrallerinin transatriyal düzeltme yapılan veya infindübüler yama kullanılan hastalara göre anlamlı olarak az bulundu.Transatriyal düzeltme yapılan veya infindübüler yama kullanılan hastalarda vena kava superiyor Doppler akımlarının incelenmesinde sağ ventrikül kompliyansının azaldığını gösteren sistolik akımın azaldığı, transanüler yama kullanılan hastalarda ise sistoldeki akımın azalmasının yanısıra kompliyans azalmasının en önemli bulgularından biri kabul edilen geri akımların da arttığı saptandı.Pulmoner arterde geç diyastolde öne akımı artan hastalarda kalp-toraks indeksinin geç diyastolde öne akımı artmayan hastalara göre arttığı; sağ ventrikül genişliğinin farklı olmadığı gösterildi. Pulmoner yetersizlik akımının süresi ve triküspit pulsed Doppler ölçümleri açısından gruplar arasında farklılık saptanmadı. Vena kava süperiyor pulsed Doppler ölçümlerinin pulmoner arterde geç diyastolde öne akımı artan hastalarda daha belirgin olmak üzere her iki grupta sağ ventrikül restriksiyonu gösterir yönde olduğu; pulmoner arterde öne akımı artan hastaların vene kava superiyor pulsed Doppler ölçümlerinin öne akımı artmayan hastalar ile karşılaştırılmasında relaksasyon bozukluğunda saptanan sistolik akımın arttığı, diyastolik akımın azaldığı; restriksiyonda saptanan geri akımların arttığı saptanarak geri akımların pulmoner arterde diyastolde artan öne akımın sadece restriksiyonu göstermediği belirlendi. Pulmoner arter sistolik akımlarının transatriyal düzeltme yapılan veya infindübüler yama kullanılan hastalarda, diyastolik öne akımların ise transanüler yama kullanılan hastalarda daha belirgin olmak üzere arttığı tespit edildi.Triküspit kapakta inspiryumda erken hızlı doluş ve atriyal sistole bağlı geç doluş dönemindeki akımların ve bunların oranlarının arttığı; ancak inspiryumda ve ekspiryumda normal solunumda olduğu gibi farklı parametrelerle de olsa relaksayonun transanüler yama kullanılan hastalarda daha belirgin olmak üzere tüm hastalarda azaldığı belirlendi.Transanüler yama kullanılan hastalarda ve transatriyal düzeltme yapılan veya infindübüler yama kullanılan hastalarda inspiryumda ölçülen pulmoner arter sistolik akım, erken ve geç öne doğru diyastolik akımların ekspiryuma göre anlamlı olarak arttığı; ancak sonuçların değerlendirilmesinde normal solunum sırasında gruplar arasında saptanan farklılıkları inspiryum ve ekspiryumun etkilenmediği belirlendi.Sonuç olarak transanüler yama kullanılan hastalarda transatriyal düzeltme yapılan veya infindübüler yama kullanılan hastalara göre daha fazla pulmoner yetersizlik oluşması, sağ kalp boşluklarının genişlemesi ve sağ ventrikül relaksayonunun bozulup kopliyansın azalması; transanüler yama kullanımının sağ ventrikül diyastolik fonksiyonlarını kötü yönde etkilediğini düşündürmüştür. Different surgical techniques are used in the surgical treatment of Fallot tetralogy, which is the most common congenital cyanotic heart disease in childhood. In recent years, diastolic functions of the ventricles have been studied in various heart diseases without entering the catheter laboratory with Doppler echocardiography and without making complex calculations. In this study, we compared patients with transannular patch and patients with transatrial correction and infindubular patch to clarify the effect of surgery technique on right ventricular diastolic functions with respect to clinical features, 2-D echocardiographic measurements and right ventricular diastolic functions with each other and with healthy children. Patients were divided into two groups according to the pulmonary arterial late diastolic forward flow which is accepted as a finding of restriction; clinical features, 2-D echocardiographic measurements and right ventricular diastolic functions were compared. On the other hand, the effects of respiration on right ventricular diastolic functions were investigated in patient groups.Pulmonary insufficiency murmur was heard in all patients with transannular patch and in 64% of patients with transtatrial correction or infindubular patch. The cardiothoracic ratio in telecardiogram was significantly increased in patients with transannular patch. There was no difference between the groups in terms of right bundle branch block in electrocardiography.In 2-D echocardiographic examination, right ventricular volume, lenght and tricuspid anulus increased in patients with transannular patch compared to normal children, in contrast, , right ventricular volume, and tricuspid anulus were similar in patients with transatrial repair or infindubular patch and normal children.In patients with transannular patch, tricuspid pulsed Doppler properties were evaluated, early rapid filling was decreased and late filling due to atrial systole was increased, E/A velocity, E/A velocity-time integral and E/total velocity-time integral were decreased; A/total velocity-time Integral was increased. In patients with transatrial correction or infindubular patch, only E/A velocity decreased and A/total velocity-time integral increased. On the other hand, E/A velocity and E/total velocity-time integrals were significantly less in patients with transatrial correction or infindubular patch.In patients with transatrial correction or infindubular patch, superior vena cava Doppler flow was examined and systolic flow which indicates decreased right ventricular compliancy was decreased; in patients with transannular patch, retrograde flow which is considered one of the most important findings of compliancy reduction, was also increased.It was shown that the cardiothoracic index in patients with increased forward flow in the pulmonary artery in late diastole was increased compared to patients with normal flow; the right ventricular width was not different. There were no differences between the groups in terms of duration of pulmonary insufficiency flow and tricuspid pulsed Doppler measurements. In patients with increased and normal forward flow in the pulmonary artery in late diastole, superior vena cava pulsed Doppler measurements indicate right ventricular restriction; it was determined that systolic flow in relaxation disorder increased, diastolic flow decreased, and retrograde flow in restriction increased in diastolic flow in pulmonary artery did not show only restriction in comparison of patients. Pulmonary arterial systolic flow was found to increase in patients with transatrial correction or infindubular patch, while diastolic forward flow was found to be increased in patients with transannular patch.Tricuspid early diastolic rapid filling and atrial filling late was increase during inspirationin altitude on the cover on the currents and their rates increased in the period; but in normal breathing during inspiration and expiration relaxation was decreased in all patients more pronounced in patients with transznular patch.In patients with transannular patch, transatrial repaired and infindubular patchpulmonary arterial systolic, early and late diastolic forward flow were increased during inspiration compared with expiration; however, the results during normal breathing inspiration and expiration did not effect the differences.As a result, patients with transannular patch had more pulmonary insufficiency, wider right heart cavities, more impaired right ventricular relaxation and more decreased compliance right ventricular relaxation impaired and decreased compliance compared with patients with transatrial repair or infindubular patch; the use of transannular patch effects badly the right ventricular diastolic function. 59

Published
1997

30. Thrombosis in the Vena Cava Inferior and Right Atrium in a Patient with Wilms Tumor.

Author

Kılınç, Burcu, Eroğlu, Ayşe Güler, Emir, Haluk, Emre, Şenol, and Celkan, Tiraje

Subjects
*THROMBOLYTIC therapy, *THERAPEUTIC use of antineoplastic agents, *THROMBOSIS, *ECHOCARDIOGRAPHY, *CONSTIPATION, *METASTASIS, *RENAL veins, *NEPHROBLASTOMA, *TREATMENT effectiveness, *VEIN surgery, *THROMBECTOMY, *VENA cava inferior, *ABDOMINAL pain, *COMBINED modality therapy, *RIGHT heart atrium, *DISEASE complications
Published
2021
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31. Coronary Events and Anatomy After Arterial Switch Operation for Transposition of the Great Arteries: Detection by 16-Row Multislice Computed Tomography Angiography in Pediatric Patients

Author

Öztunç, Funda, primary, Barış, Safa, additional, Adaletli, İbrahim, additional, Önol, Nurper Önder, additional, Olgun, Deniz Cebi, additional, Güzeltaş, Alper, additional, Özyilmaz, İsa, additional, Özdil, Mine, additional, Kurugoğlu, Sebuh, additional, and Eroğlu, Ayşe Güler, additional

Published
2008
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33. Cardiovascular side effects related with use of synthetic cannabinoids “bonzai” : two case reports.

Author

Ugan Atik, Sezen, Dedeoğlu, Reyhan, Varol, Fatih, Çam, Halit, Eroğlu, Ayşe Güler, and Saltık, Levent

Subjects
CARDIOVASCULAR disease diagnosis, DOPAMINE, MYOCARDIAL infarction diagnosis, BRADYCARDIA, CANNABIS (Genus), CARDIAC catheterization, CHEST pain, CONSCIOUSNESS, ELECTROCARDIOGRAPHY, HYPERTENSION, INTENSIVE care units, PEDIATRICS, PULSE measurement, THERAPEUTICS
Abstract

Information about the effects of synthetic cannabinoids “bonzai” on the cardiovascular system is limited. In this article, two patients in whom different cardiological side effects were observed following use of synthetic cannabinoids ‘bonzai' were presented. Our first patient who was a 16-year old boy presented to pediatric emergency department with severe chest pain which had started one hour before. On electrocardiographic examination, ST segment elevations greater than 3 mm were observed in DII, DIII, AVF and V5-V6 derivations which caused to suspicious myocardial infarction. Cardiac catheterization was performed and coronary angiographic findings were found to be normal. When the patient was questioned again, it was learned that he used synthetic cannabinoid ‘bonzai'. The second patient who was aged 18 years and addicted to synthetic cannabinoid ‘bonzai' was brought to our emergency department by his friends because of clouding of consciousness. Dopamine treatment was started in the patient whose cardiac apical beat reduced to 40/min and who was found to develop hypertension, because bradycardia worsened. However, the blood pressure increased rapidly and dopamine treatment was stopped. Heart rate and blood pressure monitoring was continued. Use of synthetic cannabinoids ‘bonzai' should be kept in mind in patients who present to emergency departments with chest pain and complaints related with the cardiovascular system. [ABSTRACT FROM AUTHOR]

Published
2015
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35. Anomalous left coronary artery from pulmonary artery (ALCAPA) in asymptomatic 11-year-old case.

Author

Koca, Bülent, Saltık, Levent, and Eroğlu, Ayşe Güler

Abstract

Origin of the left coronary artery from the pulmonary trunk [Anomalous origin of the Left Coronary Artery from the Pulmonary Artery (ALCAPA)] is a rare congenital heart defect. ALCAPA is one of the common causes of myocardial ischemia or infarction in infants and children. In this report, we present an eleven-years-old patient presenting with murmur and accompanied by echocardiographic findings of dilated cardiomyopathy and angiocardiographic investigation that revealed left coronary artery originating from the pulmonary artery. [ABSTRACT FROM AUTHOR]

Published
2012
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36. Pulmoner arterden kaynaklanan sol koroner arter anomalisi (ALCAPA) olan 11 yaşında yakınmasız olgu.

Author

Koca, Bülent, Saltık, Levent, and Eroğlu, Ayşe Güler

Subjects
CORONARY artery abnormalities
Abstract

Copyright of Türk Pediatri Arşivi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2012
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37. P Wave Dispersion in Juvenile Idiopathic Arthritis Patients With Diastolic Dysfunction.

Author

Koca, Bülent, Bakari, Süleyman, Kasapçopur, Özgür, Çelik, Emre, Öztunç, Funda, Eroğlu, Ayşe Güler, and Saltik, Levent

Subjects
ARRHYTHMIA, CHI-squared test, STATISTICAL correlation, ECHOCARDIOGRAPHY, JUVENILE idiopathic arthritis, T-test (Statistics), CROSS-sectional method, DATA analysis software
Abstract

Objective: Cardiac involvement as pericarditis, myocarditis and valvular disease is common in juvenile idiopathic arthritis (JIA). However, there are few studies concerning systolic and diastolic functions of the left ventricle in children with JIA. P wave dispersion is a sign for the prediction of atrial fibrillation. A recent study found that rheumatoid arthritis patients had an abnormally high P wave duration and P wave dispersion, markers for supraventricular arrhythmogenicity. In this study, we aimed to evaluate P wave dispersion and its relation with diastolic dysfunction of the left ventricle in patients with JIA. Methods: We performed electrocardiography and Doppler echocardiography on patients and controls. Maximum and minimum P wave duration were obtained from electrocardiographic measurements. P wave dispersion defined as the difference between maximum and minimum P wave duration was also calculated. Findings: No statistically significant differences were found between the patients and controls in minimum, maximum P wave duration and P wave dispersion. Among the diastolic parameters in patients group, increased late flow velocity, decreased early flow velocity and prolonged isovolumic relaxation time reflected diastolic dysfunction. Conclusion: During 12 months of follow-up, no supraventricular arrhythmias were documented in JIA with diastolic dysfunction. JIA with diastolic dysfunction has normal atrial conduction parameters and therefore seemingly do not have an increased risk of atrial fibrillation. [ABSTRACT FROM AUTHOR]

Published
2012

40. Üfürümlü çocuğa yaklaşım.

Author

Eroğlu, Ayşe Güler

Subjects
*CHILDREN'S health, *HEART murmurs, *CONGENITAL heart disease, *PERIODIC health examinations, *TESTING laboratories, *ELECTROCARDIOGRAPHY, *MEDICAL sciences, *PATHOLOGICAL physiology, *HEALTH risk assessment
Abstract

Heart murmur is a common finding in children. Fortunately, most of these murmurs are innocent murmurs. Innocent murmurs can be detected in 70-85% of healthy children. In contrast, the incidence of congenital heart disease is 0.8% and acquired heart disease is rare in children. Therefore, distinguishing innocent from pathologic murmur is a frequent and an important task for the physician. Heart murmurs of children can usually be diagnosed through a careful history and physical examination. If an abnormality is detected; electrocardiogram, telecardiogram and echocardigram should be ordered to diagnose the cause of the murmur. In this report, the features of murmurs, innocent murmurs, how to evalute a murmur, use of laboratory studies in diagnosis and management of a child with a murmur were reviewed. [ABSTRACT FROM AUTHOR]

Published
2009

42. A case with spontan pneumomediastinum.

Author

Şahin, Sezgin, Masoom, Mohammed Ajmal, Eroğlu, Ayşe Güler, and Taştan, Yücel

Abstract

Spontaneous pneumomediastinum is the presence of free air in the mediastinum without any identifiable etiology like trauma or invasive procedure. Hower thoracic pain is the major complaint. The symptom triad of thoracic pain, dyspnea and subcutaneous emphysema is typical. We present a 13- year old young male presenting to the emergency room with a complaint of thoracic pain. Physical examination was unremarkable except for Hamman's sign. Examinations including chest x-ray revealed pneumomediastinum. In this case, when evaluating thoracic pain, we aimed to emphasize the importance of physical examination particulary the cardiac auscultation. [ABSTRACT FROM AUTHOR]

Published
2013
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43. Kendiliğinden gelişen pnömomediyastinum olgusu.

Author

Şahin, Sezgin, Masoom, Mohammed Ajmal, Eroğlu, Ayşe Güler, and Taştan, Yücel

Subjects
PNEUMOMEDIASTINUM
Abstract

Copyright of Türk Pediatri Arşivi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2013
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44. Voriconazole Induced Bradycardia.

Author

Uluda, Dilek, Özdemir, Nihal, Tüysüz, Gülen, Eroğlu, Ayşe Güler, and Celkan, Tiraje

Subjects
BRADYCARDIA, ANTIFUNGAL agents, COMMUNICABLE disease treatment, MYCOSES, ACUTE leukemia, HEART rate monitoring, DIAGNOSTIC microbiology, PEDIATRICS
Abstract

Voriconazole is a triazole antifungal drug that is used to treat invasive fungal infections, especially aspergillus. Here, we report two children who had severe bradycardia associated with voriconazole at a dose of 12 mg/kg per day. Bradycardia resolved in 24 hours in both after decreasing the dose to 10 mg/kg per day. Heart rates were in normal limits on follow-up. Bradycardia may be a side effect of voriconazole treatment in children under immunosuppressive treatment. Heart rate should be monitored in patients receiving voriconazole and other triazole treatments. [ABSTRACT FROM AUTHOR]

Published
2013
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45. Intractable atrial flutter presented with severe bradycardia in an infant.

Author

Barış, Safa, Güzeltaş, Alper, Seymen, Gülcan, Özyılmaz, Isa, Eroğlu, Ayşe Güler, and Öztunç, Funda

Subjects
ARRHYTHMIA in children, BRADYCARDIA diagnosis, ELECTROCARDIOGRAPHY, KARYOTYPES, TACHYCARDIA
Abstract

The article presents a case study of a 3 months old infant with bilateral congenital cataract. Electrocardiography revealed bradycardia with a ventricular rate of 57 bpm and intraventricular conduction block. Several tests included etiology of the cataract, genetic karyotype and infectious analysis. It concludes that atrial flutter is a rare tachycardia in the newborn and young infant and usually has an excellent prognosis and it can be the reason for persistent bradycardia.

Published
2009

47. Editörden.

Author

Eroğlu, Ayşe Güler

Subjects
*PEDIATRICS
Published
2017

49. Angiography findings after late bidirectional cavopulmonary shunt operation at mid-term follow-up.

Author

Koca, Bülent, Eroğlu, Ayşe Güler, Gökalp, Selman, Saltık, Levent, and Öztunç, Funda

Subjects
*SURGICAL anastomosis, *HEMODYNAMICS, *OPERATIVE surgery, *PULMONARY artery, *PULMONARY blood vessels, *ARTERIES
Abstract

This article discusses a study which examined the hemodynamic data of patients after late bidirectional cavopulmonary shunt. The study investigated the suitability of older patients for modified Fontan operation. It identified the mean pulmonary artery pressure of the patients. It showed the suitability of 73.9 percent of the patients for modified Fontan operation.

Published
2011
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