851 results on '"Ernst, Beat"'
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2. Analogues of the pan-selectin antagonist rivipansel (GMI-1070)
3. Does size matter? – Comparing pyranoses with septanoses as ligands of the bacterial lectin FimH
4. Thermodynamics-Guided Design Reveals a Cooperative Hydrogen Bond in DC-SIGN-targeted Glycomimetics
5. Strengthening an Intramolecular Non‐Classical Hydrogen Bond to Get in Shape for Binding.
6. Does targeting Arg98 of FimH lead to high affinity antagonists?
7. Antiadhesive natural products against uropathogenic E. coli: What can we learn from cranberry extract?
8. Combating DC‐SIGN‐mediated SARS‐CoV‐2 dissemination by glycan‐mimicking polymers
9. Tetra‐ and Hexavalent Siglec‐8 Ligands Modulate Immune Cell Activation
10. FimH antagonists prevent biofilm formation on catheter surfaces
11. Combating DC‐SIGN‐mediated SARS‐CoV‐2 dissemination by glycan‐mimicking polymers.
12. Selective in vivo removal of pathogenic anti-MAG autoantibodies, an antigen-specific treatment option for anti-MAG neuropathy
13. 2-C-Branched mannosides as a novel family of FimH antagonists—Synthesis and biological evaluation
14. SIGLEC-4 (MAG) Antagonists: From the Natural Carbohydrate Epitope to Glycomimetics
15. Nature of the Interaction of Alpha-D-Mannose and Escherichia coli Bacteria, and Implications for Its Regulatory Classification. A Delphi Panel European Consensus Based on Chemistry and Legal Evidence
16. A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewisx Mimetics
17. Nature of the Interaction of Alpha-D-Mannose and Escherichia coli Bacteria, and Implications for its Regulatory Classification. A Delphi Panel European Consensus Based on Chemistry and Legal Evidence
18. Tetra- and Hexavalent Siglec-8 Ligands Modulate Immune Cell Activation
19. Quantitative profiling of prostaglandins as oxidative stress biomarkers in vitro and in vivo by negative ion online solid phase extraction – Liquid chromatography–tandem mass spectrometry
20. Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8
21. Prodruggability of carbohydrates--oral FimH antagonists
22. pKa determination by 1H NMR spectroscopy – An old methodology revisited
23. Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth
24. Chemical Development of Intracellular Protein Heterodimerizers
25. A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewis x Mimetics.
26. Substrate and donor specificity of glycosyl transferases
27. Design, synthesis and biological evaluation of mannosyl triazoles as FimH antagonists
28. Prodrugs of E‐selectin Antagonists with Enhanced Pharmacokinetic Properties
29. A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN
30. E-selectin ligand complexes adopt an extended high-affinity conformation
31. GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice
32. Kinetic and thermodynamic properties of MAG antagonists
33. Design, synthesis, biological evaluation, and modeling of a non-carbohydrate antagonist of the myelin-associated glycoprotein
34. Probing the carbohydrate recognition domain of E-selectin: The importance of the acid orientation in sLe x mimetics
35. Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2
36. The intrinsic conformation of a Lewis antigen: The Lewis × trisaccharide
37. Design, synthesis and evaluation of monovalent ligands for the asialoglycoprotein receptor (ASGP-R)
38. Poly‐l‐lysine Glycoconjugates Inhibit DC‐SIGN‐mediated Attachment of Pandemic Viruses
39. Differential recognition of oligomannose isomers by glycan-binding proteins involved in innate and adaptive immunity
40. Prediction and Validation of a Druggable Site on Virulence Factor of Drug Resistant Burkholderia cenocepacia**
41. Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2
42. E-selectin ligand complexes adopt an extended high-affinity conformation
43. Epitope Structure of the Carbohydrate Recognition Domain of Asialoglycoprotein Receptor to a Monoclonal Antibody Revealed by High-Resolution Proteolytic Excision Mass Spectrometry
44. New sialyl Lewis x mimic containing an α-substituted β 3-amino acid spacer
45. Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists?
46. Trivalent, Gal/Gal NAc-containing ligands designed for the asialoglycoprotein receptor
47. Tarsal contact chemoreceptors of the cherry fruit fly, Rhagoletis cerasi: specificity, correlation with oviposition behaviour, and response to the synthetic pheromone
48. Implications of the E-selectin S128R mutation for drug discovery
49. Biochemical characterization of Helicobacter pylori α-1,4 fucosyltransferase: metal ion requirement, donor substrate specificity and organic solvent stability
50. From carbohydrate leads to glycomimetic drugs
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