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This work presents a study of the processes of digitalization of the economy in the context of assessing the role of investments in the development of digital technologies as the key drivers of the development of information systems management. Theoretical aspects of the formation and development of information systems are considered, their classification and general characteristics are given, general trends of transformation of information systems under the influence of digital technologies are established, and directions and volumes of investments in the digital economy from the position of their impact on the development of information systems are determined. The research methodology is based on the systemic approach and is characterised by the "blurring of the boundaries" of certain research spheres within such concepts as "digital economy", "information system", and "venture investment and start-ups". The methodological tools of this study include analysis and synthesis, specific historical methods, expert analyses, observation, and generalisation. This research is a stage in substantiating the connection between the factors of investments in the digital economy and the reflection of their impact on the management and development of information systems. The empirical study of the connection between the considered processes and justification of the key trends and directions for their development form a theoretical basis for mathematical models that are aimed at determining concrete sets of factors of investment effect on the designated range of the elements of the digital economy with further reflection of this effect in the form of economic results of companies' activities. [ABSTRACT FROM AUTHOR]